LOCUS       c00016_JAHBRO0..       22160 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHBRO010000023.1 Streptococcus thermophilus strain Brie16
            Contig_23, whole genome shotgun sequence.
ACCESSION   JAHBRO010000023
VERSION     JAHBRO010000023
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:26:25
            Original ID  :: JAHBRO010000023.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 21234
            Orig. end    :: 43394
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22160
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[31234:33394](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12160
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..22160
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22160
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(1263..1673)
                     /locus_tag="ctg16_39"
                     /transl_table=11
                     /translation="MNFKQLKNFDFKNIDINRNQFEHITVGLIILCALSLLLVTIKTQH
                     SIKIDGTKITYKGQMQNHRLNGQGTLTYDNGDTYTGGFKNGSFNGQGTFKSHEGWTYEG
                     EFKSGQADGQGKLTTENKVIYKGKFTQGIFKG"
     CDS             complement(1670..2104)
                     /locus_tag="ctg16_40"
                     /transl_table=11
                     /translation="MNKVVFVCLGNICRSPMAEFIMKALDQDGSLHIESRATSSWEHGN
                     PVHQGTQKILRKYGVSFDSSKGSQQISQSDFEFFDLIVGMDESNVEDLLQVSAGRYDDK
                     IKLFRPGGVPDPWYTGDFEETYNLVTAACQDWLQWIRDRQ"
     CDS             complement(2387..3679)
                     /locus_tag="ctg16_41"
                     /transl_table=11
                     /translation="MTSVVVIGTQWGDEGKGKITDFLSQDAEVIARYQGGDNAGHTIVI
                     DGKKFKLHLIPSGVFFPEKISVIGNGVVVNPKSLVKELEYLHTEGVSTENLRISDRAHV
                     ILPYHIKLDQLQEAAKGDNKIGTTNKGIGPAYMDKAARVGIRIADLLDKEIFASRLKTN
                     LAEKNRLFSKMYESEELSFDEIFEEYYAYGQQIKQYVTDTSVILNDALDAGKRVLFEGA
                     QGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTEL
                     FDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNCIDVLSGLDTV
                     KICVAYDLDGERIDYYPASLEQLKRCKPIYEELPGWEEDITGCRSLDELPENARNYVRR
                     IGELVGIRISTFSVGPGREQTNILESVWSNI"
     CDS             complement(3933..4451)
                     /locus_tag="ctg16_42"
                     /transl_table=11
                     /translation="VLKIAIIGYSGSGKSTLANFLGQHYNCEVLHLDKIHFTSNWQERT
                     VDEMTDDISTFMLQSDWIIEGNYSACLYEERMREADCIVYFNFNRVNCLYRAFRRYLTY
                     RGKTRPSMAEGCNEKFDFAFVKWILLDGRSKKYVEQYNAVVKNYSDKTIVLKNQKQLNN
                     YMKKVKKLL"
     CDS             complement(4738..5907)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 67.6; E-value: 1.7e-20)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_43"
                     /transl_table=11
                     /translation="MIKKQIFHYLFATFLVTVAYTLPHSILTVLLLEKGLSISQILIIQ
                     SAYSLAIILFEFPSGMLSDNWSRKYLYLSSRVLLIIMFLIVLISSNFYFLYLAWFIYGI
                     AAAFESGTLDSYLINKLKRSSNDKLIESFISKDNKIQFASMIIGSGIGGILYFMIGIKI
                     YIIAIILVCLSIFDIGFFFQEDRDYYKEKINIDTFKKQISISFKELKENSILRVIIVFD
                     LLTQLFFQAHFQLWQSFLLEKGIDKRYFTAFYFLFQIISILSYSIHTDKLQKLVNYRLF
                     LLLVIALPLFFLSNLPVVYLIAYILYVFIFYIIQFVLNIYFNKQVSTKTISSLISLKST
                     ISRISGLLILYALSFLLNYMSVSLVISLAFILSLLSILLLLNYFIKNYI"
     CDS             complement(5900..6955)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_44"
                     /sec_met_domain="ThiF (E-value: 1.5e-36, bitscore: 119.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKTSLTATTLKSNENLIGIGSKQYTVNDDEFNLSLKILEFLLT
                     EKDEDEILNWLDSNNIDKSIFKKLVANKLITTSKAVFQKEDTMEFKNGLYLDLIINNVQ
                     DVLTKFKETTFVVIGCGGIGNFMSYALSVYSPKKLVLIDGDKIERSNLNRQFLFTINDI
                     GKYKSEVIADALKLRNPNLDIEVYTEFISTNNINNILEGKDTNSMFGILSGDDDTAVSI
                     SSKYFLTNNVPFVNIGYLNDIAVISPFVIPHKTSCPFCYGTFSINGEINSNDETMAQLH
                     KQYASPSSIINNSLACDLALSDIIQYFAGNNDSIKSLNARVGINSNSFEKYVLPNTKDP
                     NCSICGGTLDD"
     CDS             7485..8660
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 412.1; E-value: 2.9e-125)"
                     /gene_kind="other"
                     /locus_tag="ctg16_45"
                     /transl_table=11
                     /translation="MTQFTTELLNFLAQKQDIDEFFRTSLETAMNDLLQAELSAFLGYE
                     PYDKLGYNSGNSRNGSYARKFETKYGTVQLSIPRDRNGNFSPALLPAYGRRYDHLEEMV
                     IKLYQTGVTTREISDIIERMYGHHYSPATISNISKATQENVATFHERSLEANYSVLFLD
                     GTYLPLRRGTVSKECIHIALGITPEGQKAVLGYEIAPNENNASWSTLLDKLQNQGIQQV
                     SLVVTDGFKRLEEIINQAYPLAKQQRCLIHISRNLASKVKRADRAVILEQFKTIYRAEN
                     LEMAVQALENFIAEWKPKYRKVMESLENTDNLLTFYQFPYQIWHSIYSTTLIESLNKEI
                     KRQTKKKVLFPNEEALERYLVTLFEDYNFKQNQRIHKGFGQCADTLESLFD"
     CDS             8794..8883
                     /locus_tag="ctg16_46"
                     /transl_table=11
                     /translation="MTTQNLNKLPGTIAVPMDKIRITIYCPSF"
     CDS             9044..9916
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_47"
                     /sec_met_domain="TIGR01716 (E-value: 9.2e-31, bitscore:
                     100.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTIDIGSLTKKIRLSKKLSLKDVAGDYLSVSFLSKFERGESEI
                     SLSRFLCILENLDVSIEEIYGILSKDNPTRTEELLARVSKAFQQNNIPALKKYYYEEIE
                     KFNSTHKKIFLYNSILIDSFLISITGKKMNKKHIEVISDYLFDVDQWGKRELVILGNSM
                     SAVPTNTLNLLIKEIIYKTTLFGNNEENKKIKIDLILNGISIFLERKELNYAKFYIDLF
                     DTLTIPEVYLYERVEYNILIGTYWILIGKIEVGKKKIELALESLKNLGAENLLLMRENE
                     YEELLNSII"
     CDS             10001..12160
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_48"
                     /sec_met_domain="LANC_like (E-value: 7.8e-08, bitscore:
                     24.7, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.6e-14, bitscore: 45.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELITPSEKRIINRKKGEIYDYISYSNAFVPYQGWKIHISANLI
                     DYQSILDNVYHVCSIFQTPFKYINKISELFRILSKHVSQLEIGKFITIYPKNKETFLLL
                     LEELYDKIPKYTGVQILTDRSYKDSEIIFYRYGVMNARLINNERPKLKFNGTFYEDITE
                     PYYTCPPFVEDIIFNKVVDDYNIESLFHDRYQMESIIHKSGAGNVYIAIDTINEEKVII
                     KEARKKVYITEKILAIDLLLNEKCILKKLKGKVDIPNYIECFTIEGNLYLVEEFIDGQR
                     LDILKPEYNLLIKRNSSELGRYNKKVKKIISNLFLSLYKIHQEGIILEDISSSNILLTN
                     DDRVFFIDLETAYNKNDGIIVETTNECYPKNISQKNEQRDIVKMWYCIIDLLTNSTSLL
                     KYDNTGVSTLNLFYKMSLENNLPKSLRKKFINDFSIVDFKNTFIIKFIEMGLNIEKIVR
                     MQQDLTETILSHNTFEIYGKTILESIDNYKHISNMDLKFSSDPSFSSLYDNCNKSIDDL
                     IGIAILDNNFELFLNCNLDELLHNMSYYQKYYLLRLFNDTKICDRVYFIKVLNSIIKND
                     IKCIDGVKYIKSNEYFSPYLITGNSGLIIELIKFSKNNNTMKFDEWIRSLSEGISYTYA
                     KGTSLYYGLAGLGLANAWLYYYFKETSFLKTSIKICEHIFDFSIKQNTKTILIDPMSEE
                     IDYTYSKGMLGQLYFINELLNIIKE"
     CDS             12165..13733
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 125; E-value: 6e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_49"
                     /transl_table=11
                     /translation="MKKYILKYKLLNLIHIILIGFSSAFLVGASVTLSIMLNKLVESDF
                     KGFLIWLGIEFGVYLLFLADTYLIRVNQTKLIQKMTLSLRDDYINSLTRKSFSEFKNKT
                     VGEHLSILNNDIKIIEESGFESFYSLVSTVFTTFFSIIALFSYDYRIVLLSILLTLILT
                     YLPRSFAHKMEKAMKRFSIGNETFISSLTDQLLGYDTLYYSNKKEMLSIKCGEVIKKFI
                     FEKIVFIKTSSLIEIIMSLFSIISQMLVLLLTGYLIILKQVSIGSISSVGQISGNIFNS
                     LTTFNQLQVSISSVNIIFEKFGAFEKSSHYRYIDKDIEEIKLTNVGYSFKDKEIFKNIN
                     CSFEKGKNYAIVGESGSGKSTLINIILGNNKQYSGSVKYNDVEISDIEESQLFKSVSYI
                     GNITHIYHDSLRNNLTLWDNKINESEIINILKQVNLIDLIPRLDDEVSMSFLSEGQKQR
                     LGIARAYLTKTNVIIMDESMANLDRDNAFLIENQLLNDPTRMYITVSHHLQEKLLDRFH
                     SIITL"
     CDS             14648..15346
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_50"
                     /sec_met_domain="TIGR01716 (E-value: 2e-47, bitscore:
                     154.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIEEFVYAVRDFRRDDFNELLEKIRYLVSNRDIDGMKKLLISQM
                     EKKDKKEPFASFNTILIKIRLQDLSGETYVTDQEIVTISDYLFSAEYWGYYELLLFMNT
                     IDALNHNTMMILAKEMCHRLDFYRDIPNNRRLLATMLLNAYITCIERNEWMDALYFEKQ
                     PKYCNFSETEMYEKLVLHYANNLYDLKKNNNRHAVLEMRKCIAATKLVDSNQISIKFEN
                     YLQKVLDDMR"
     CDS             15424..15531
                     /locus_tag="ctg16_51"
                     /transl_table=11
                     /translation="MEKLQVIDLEELLEFDQGYVINASCGPSHSCGGGR"
     CDS             15588..15722
                     /locus_tag="ctg16_52"
                     /transl_table=11
                     /translation="MIKTIETDIGTYYFDSVNFTLSLSPISKQSSPTLDSVEDGVLKK"
     CDS             15791..16786
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_53"
                     /sec_met_domain="Fer4_12 (E-value: 1.7e-08, bitscore: 28.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNRIMDLTTADNIIQEIASKGVTQINRLILFGGEPFLNIELFIY
                     FIEKLSTLLNVVKIETVTNGTVLNKRVKEMLVKFHPYLTISLDGPEIVHDRLRGRGSHR
                     KTLRFINYLKNIDYENFEIASTYTRLHQKNGLSREDIFQYFTDMDVHFNINDVFTKNKV
                     LIVKEMEKSLAERKQFIDKSIQHVINNNEKAFISPILYDVLISMIYKSTNRTFCDDIDP
                     SNTLTYDVDGSKKLCFRFWGTHNSPKAESFNNKDNFEKCKNCWCRGMCLECVANVIDGY
                     SSVISEDGEFLECSKPELMEYCIKQIIYLSKDREKLSRLVNNFRGFIRYA"
     CDS             16779..18320
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 150.2; E-value:
                     1.4e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_54"
                     /transl_table=11
                     /translation="MLRSYVTKKHLTFYFLAIVITWLEAIITPALIQYIVASFTNRQLH
                     LLWQILLWGIGGNLVLVLGLAGKRYYYARLMTDFKVGIKRAIFRTFLYSRQIPDEEVLS
                     DLENDVQQLENSYIEPTVIIVSSLGFTVVSIAYALWTNFYLGLLFIIFYSVPVLCSGLG
                     SKRLDRIAEQKSLANQNYIARVNNMIAGVAPIRHYQGQNLFFKRFSKDLEQALQEEVSY
                     EKQRSLNSLFINSIDAFCSVAPIVIGGFMTYQNYLSAASFVGIYLVSHNIGYQFQELSY
                     FINTRKSAKSLCDKYQDLFGNKLATDSIFDQSVFPIQLEQVSVEKDGETILAPCDLTIH
                     AGEKIAIIGESGAGKTTLLNILYGEIHPSQGQIRYQGRELTSCQLYQAGAYILQSSHVF
                     DDLSVEENIALGQEIDQQRMDNILQETGLLSLKGKVPSNQTLSGGEKQRLEIARALYHK
                     RQFILADEVKANLDAKNQEKINQLLFSLPQAVVEVIHHYTKEDLKRYDKVIHLKK"
     CDS             complement(18724..19236)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 59.3; E-value: 1e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg16_55"
                     /transl_table=11
                     /translation="MTFIIQNFGPNLARLRIEKGVSQTQLAEDLGIGKQSISDYEKQKS
                     YPTFANLDKIAEYFNATPTQLFGTSKEIELEKSVLESNEYSDKVSEILKAVKYIENFLE
                     TDGQYLEDLLYLTRGKQLYTEDGDELYTDPTSQKRTFHNQYEPGFIVARDKSPLELLIE
                     NKELFDK"
     CDS             19645..20001
                     /locus_tag="ctg16_56"
                     /transl_table=11
                     /translation="LLISIQDLRSIQERCEIGELVQRLDVSIDRLTVIWDTDTGPLRRI
                     FKNLKQAISTRVDSFEIHDNVRDDVFTLAKDFNEYDSINIIFFQLSTYGGEQLIRIDFN
                     PNTLKEFDGMKVWR"
     CDS             20005..20622
                     /locus_tag="ctg16_57"
                     /transl_table=11
                     /translation="MYFARLNSLTVRLSRFDLAFDIFNRPEIVNLQHIKGGVTHKVFYG
                     RGGELETKYWGSSGSNVQVRLYDKNKEIIAHKHEEKLDLGVNPFWWRLEFQLRTKAIGE
                     DMVQDIMNRLDNFGFYKLEHIRVDQRAFTIIFLSNPELLSLAFPNLKSDSIKKKKTRVR
                     KLLREETNQFAEELKEVLIQNLPKLNTELQLLVGEFLTLENQ"
     CDS             20634..20822
                     /locus_tag="ctg16_58"
                     /transl_table=11
                     /translation="MDNNLISNKELIEMGYRPHTANDIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVNEILGTEVA"
     CDS             20824..21963
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 86.3; E-value: 5.4e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg16_59"
                     /transl_table=11
                     /translation="MASVLYRKRGDSNLWTYEIRNEGKTVAHNSGFKTKKLAESEAEPI
                     LQELRLGKRISRDISLADLYQEWLELKILPSSRSEETKKKYLLRKNTIERLFGNKKVTQ
                     IRASEYQRIMNKYGQTVGRNFLGRLNTGIHQSIQMAIADKVLIDDFTQHVELFSSKEQQ
                     MTEEKYLHTEKDYLDLLLAVKRKFDYQRSIVPYIVYFLLKTGMRFGELVALTWNEVDFD
                     RGLLKTYRRYNTLSHKFVPPKNKTSIRMVPIDEECIKILRLLQTEQERANMELGIKNRY
                     RMIFQHFGYIHSVPDIASVNKALSVLLNELDIYPIITTKGARHTYGSYLWHKGFDLGVI
                     AKILGHRDISMLVEVYGHTLEEKIFEEFNQIRDIWKDCS"
ORIGIN
        1 ttgactgttt tcagcattgg tacgtgttaa tttcatcttc gtctgagctt gtgacaatcc
       61 cttagctacc aaatctttct caaagttccc aacagctggc gcaaagagag aaatgagcac
      121 tgtaattaag gtgagcccac tgaagatata gagcacaata tgtcggtaag gtgtcaagtc
      181 caaatctatt ccaaagagac ttccctttct tcccgcaata aacggctcta ttatatagta
      241 ggaaagtgtt gcaaaaacga ttgacaaaat tgttgtcagt atgactgcaa tgatattatt
      301 ggttaattgg ctgaagataa tatatagcgg ccagtggaac aaataaacgc tgtaactgat
      361 ttccgccaaa taactaataa aagcaggctc tgatttgcca ggtagcttct catggagaat
      421 acgtgcggag taaatcatga cagctgtaaa caaactagcc aaaacaaacc caaatagata
      481 ggtaatacgt tcttcaaaat gaaggactaa gcccaacaat aagagcagag caaagctacc
      541 aaccatataa agaactgtct ttttaagttc ccataggtga acatttttct taaacctagc
      601 agtcgtctca tgtacacctg aaagtgtcgc aagaatcgaa cctaaaaaga aaggataagc
      661 gtgcgtgatt gaagaaaaat acaagcgaga aaaaccatca acaaagaaag cactaataaa
      721 cattgatagg aaactcaccg taaagcaggt aagagatacc atgaaaacta ggcctctaaa
      781 ttgattttga tgcttaacaa gctttgctag gaaccaaagt aaggcacccc agagaatata
      841 ataatgaacc tcaatagcca gactccatgt atggaggtag atatgctggt taaactgatt
      901 ctcataattc cccccagtta aaatttcata atagttagtt acaaaaccaa taacagaggt
      961 gatctgatgc ccgatgcctg caatgaaatc atttcgaacc aagagtgcta aaggggtaca
     1021 gataagaacc atcagtacaa gtgggggtac tatacggtaa aagcgtcgtc gcataaaacc
     1081 aagataatca atgcgatgtg tcctagacat ctcatcaatc aaaagtgccg taatcagata
     1141 gcctgaaaag gtaaagaaga catcaacacc aatgaatccc ccaggaagaa cgcttggaaa
     1201 aaaatgatag acaagaacta aaaggagccc tgtcacacga atataagaaa accagttaat
     1261 tctcatcctt taaaaatccc ttgtgtaaat tttcctttgt agataacctt attttcagta
     1321 gtcaattttc cttggccatc tgcttgacca gacttgaact ctccttcata agtccaacct
     1381 tcgtgagatt taaaagttcc ttgaccatta aaagaaccat ttttaaatcc acccgtatag
     1441 gtatcaccat tatcataggt cagagttcct tgaccgttta aacgatggtt ctgcatctga
     1501 cctttatagg tgattttagt cccatcaatt ttaatagaat gttgcgtttt tatagtcacc
     1561 aacaacaagg acagagcgca taaaataata agccctaccg tgatatgctc aaattgatta
     1621 cgattaatat caatattttt gaaatcaaaa ttctttagct gtttaaaatt cattgtctat
     1681 ccctaatcca ctgtagccaa tcttggcaag ctgcagttac caaattgtat gtttcttcaa
     1741 aatcacctgt gtaccatggg tctggaaccc caccaggtct aaagagctta attttatcgt
     1801 cataacgacc cgcagatact tgtaggagat cctcaacatt tgactcatcc atccccacaa
     1861 tcagatcaaa gaattcaaaa tctgactgac ttatctgttg tgagcctttg gaagaatcaa
     1921 aagaaacccc atatttcctt aaaatctttt gagttccttg gtgaactgga tttccatgtt
     1981 cccaagacga agttgcacga ctttcaatat gcaaagaccc atcttggtca agcgctttca
     2041 ttataaactc cgccataggg cttcgacaaa tatttcccag acaaacaaat acaaccttat
     2101 tcattactca cctcttaccc caaagctatt aagaaatttg ctcacttatt ctcttggtta
     2161 caattgttgc tatactccta aatcatgaaa gtaggttctc gttaattttc atttaatcaa
     2221 accatattat accgaaaaac taatcaaata gaaagatttc tcttctaata ctatcgaaaa
     2281 attgacacgc gtttttttta acagttacca agtcatttag gaccttatta tgtttactga
     2341 ctaaagaaaa aaagaaccta gtttcctaga ttctttatct tcattattag atatttgacc
     2401 aaacactctc aagaatgttt gtttgttcac gtccaggtcc tacagagaag gtagagatac
     2461 gtataccgac caactcacca atacgacgaa cataattacg ggcattttca ggaagctcat
     2521 ctaaactacg gcaacctgta atatcctctt cccaacctgg caattcttca taaattggtt
     2581 tacaacgttt caattgctca aggctagccg gatagtaatc aatgcgctca ccatcaagat
     2641 cgtaggctac acaaattttc acagtatcaa gaccagaaag aacatcgata cagttcaagc
     2701 taaggtttgt aatacctgat acacgacggc tatgacgcat taccactgag tcaaaccatc
     2761 ccacacgacg tggacgtccc gttgttgttc catattcatg gccaacttca cggatacgtt
     2821 cacccacttc atcaaacaac tcagttggga aaggaccatc gccgacacga cttgtatagg
     2881 ccttacatac acccacaacc ttattaattt tagatggccc aacaccagaa ccaattgtaa
     2941 caccaccagc aactgggttt gatgacgtta caaatgggta tgttccttgg tcaatatcaa
     3001 gcataactcc ttgagctcct tcaaagagga cacgtttacc tgcatcaaga gcatcattca
     3061 agataacaga tgtatctgtg acgtattgtt taatttgttg tccgtaggcg tagtattctt
     3121 cgaaaatctc atcgaatgat aactcttcag actcatacat cttactgaaa agacggtttt
     3181 tctcagccag gtttgtcttc aagcgactag caaagatttc tttgtccaaa agatcggcaa
     3241 tacggatacc aacacgcgca gccttatcca tataggccgg accgatacct ttgttagttg
     3301 taccaatttt attgtcacct ttagcagctt cttgcagttg atcaagttta atatggtatg
     3361 gcaagataac atgtgcgcgg tcagaaatgc gaagattctc tgttgataca ccttctgtat
     3421 gaagatattc caactctttg acaagtgatt taggattcac tacgacacca ttaccaatga
     3481 cagagatttt ctctgggaag aaaacacctg atggaatcaa gtgcaatttg aatttcttac
     3541 catcgataac aatcgtgtga cctgcattgt ccccaccttg ataacgtgca attacttcgg
     3601 catcttgact taggaagtct gtgattttcc ctttaccttc atcaccccac tgggtaccta
     3661 taacaactac tgatgtcata ttattttgat aacggacagc tccatcttta cgagactgtc
     3721 cccacctttc ttgaaaaact tcacggtggg aatttcaccc acaagttttg cgttacagtt
     3781 tattatatca gaaaagagac taattgttca acgatgaaat cttttatatc aaaatattct
     3841 gacagttaca atccagattg caactaatta cttactatat tttttaatct cttatcttat
     3901 atagagctat caactatttt atgagtaaat agttatagca gttttttaac cttcttcata
     3961 taattgttta actgcttttg attctttaaa actattgttt tgtcagaata atttttaaca
     4021 actgcattat attgctctac atatttttta gaacgtccgt ctaataaaat ccatttcaca
     4081 aatgcaaaat caaatttttc attacagcct tctgccatgc taggacgtgt ctttccccta
     4141 tatgttaaat aacgcctaaa cgcccgatag agacaattaa ctctgttaaa gttgaaatag
     4201 acaatacagt cagcttccct catacgttct tcataaagac aggccgagta attcccttca
     4261 ataatccaat cactttgtag cataaatgtt gatatatcgt cagtcatttc atcaactgtt
     4321 cgctcttgcc aatttgatgt aaaatgaatt ttatctaaat gaagaacctc acaattgtag
     4381 tgttgaccta aaaagtttgc caaagtagac tttccagagc cactatagcc aatgattgca
     4441 attttcaaca catgcctcct tcttcaattc tattgcttga ctgatattat aacataaagc
     4501 agatatctta cgaggcaata attcatgttt aaacaagcaa aaaaagcctt gtaaatcaag
     4561 gcttttcctg ttgtatttag atgcccccta caggtagttt atagagattt atacatatag
     4621 agaaaaggat ttttattgat tttatgcgat tttagtatct ttatatttta aaagaatttt
     4681 tgtttcgcaa caaattcgca acaagttttg tttcatattt tatcttatac tacatagtta
     4741 aatataattt ttaataaagt aatttaataa caataatata gataaaaggg agagaatgaa
     4801 tgctaagctt atcacaagac taacgctcat ataattcagt aaaaaactta aagcatataa
     4861 aattaataat ccacttatcc tagagattgt tgacttgaga gatattaacg aagatattgt
     4921 tttcgttgat acctgtttat taaaatatat atttaggaca aattgaatta tataaaatat
     4981 aaagacatat aaaatatagg ctataagata aactacgggc aagtttgata agaaaaataa
     5041 aggcaaggca ataactaata agagaaataa tcgatagtta actaactttt gtagtttgtc
     5101 tgtatgtata gaataggata ggatactgat tatttgaaaa agaaaataga aagctgtgaa
     5161 atatcgttta tcaatacctt tttccaataa aaaggattgc cacaattgaa aatgtgcttg
     5221 aaaaaataac tgtgttaata agtcaaaaac aataataact ctaagaatac tattttcttt
     5281 tagctcttta aaacttatag aaatttgttt cttaaaagta tctatattta ttttttcttt
     5341 atagtaatct ctatcttctt ggaagaaaaa gccaatatca aaaatagata aacaaactaa
     5401 tattatagca ataatatata tttttatacc tatcataaaa tatagaatac cacctatacc
     5461 actaccgata atcatagatg caaattgaat tttattatct ttagaaataa aagattcaat
     5521 aagtttatca ttagatgaac gtttcaattt atttattaaa taggaatcca aagtaccgct
     5581 ttcaaatgct gctgcaatcc catatataaa ccaagctaaa tataaaaaat agaagttgga
     5641 agatataagg acaataagaa acataattat taataaaact cttgatgata agtataaata
     5701 ctttcttgac caattgtctg atagcattcc acttggaaat tcaaacaata taattgctag
     5761 actgtatgca gactgtatta ttaatatttg agaaattgat agtccttttt ctagtaataa
     5821 gactgtaagt attgaatgag gtagtgtata ggcaactgta actaagaaag ttgcaaatag
     5881 ataatgaaaa atttgttttt taatcatcta gtgtgccacc acatatacta cagttagggt
     5941 ccttggtatt aggtaggaca tacttttcaa aggagttact attaataccc actcgagcat
     6001 taagggattt tatactatca ttattacctg caaaatattg aataatatcc gatagcgcta
     6061 aatcacatgc tagtgaatta ttaataatac ttgatggtga ggcatattgt ttatgcaact
     6121 gtgccattgt ttcatcatta gaattaatct cgccgttgat tgaaaatgtt ccataacaga
     6181 aaggacaaga agttttgtga ggaataacaa aaggactgat tacagcaata tcatttaaat
     6241 aaccaatatt tacaaatgga acattattgg tgagaaagta ttttgatgat attgaaacag
     6301 cagtatcgtc atctccagat aatatcccaa acattgaatt agtatctttg ccctcaagaa
     6361 tattattgat attattagta cttataaact ctgtatatac ttcaatatca agattaggat
     6421 tacgtaattt tagtgcatca gcaattactt ctgacttgta ttttccgata tcgtttatcg
     6481 taaatagaaa ttgtctattt aagttacttc tttcaatttt atcaccgtcg ataagaacta
     6541 attttttagg agagtagacc gataaagcat aactcataaa gtttccaatg ccaccacaac
     6601 caataacgac aaaggttgtt tctttaaatt tagttagaac atcttgaacg ttatttatta
     6661 ttaggtccag ataaagtccg tttttaaatt ccatagtatc ttctttttgg aaaacagctt
     6721 tactagtagt gattaattta ttagctacta attttttaaa aatcgactta tcaatattat
     6781 tactatctaa ccagtttaag atttcatctt catctttttc tgtaagtaga aattctagaa
     6841 tctttagtga taaattgaat tcatcatcat taactgtata ttgtttactg ccaataccaa
     6901 ttaagttttc attagatttt agtgtagtag cggttaagct tgttttgtat ttcataaatt
     6961 aatccttccc atttataata aaaaaatcta tttaactata tcaagagata tagccaaata
     7021 gattaaaccg attaaccaag tgtggttagt tcaagattgt ccctttcata ttgggtacct
     7081 ccttcatatt tttagacaat tatacgccgc atgaaaaata atgtcaattc aaaaaattct
     7141 gaactttact ttttttaatt tttgttattt ttttattttc atattggttg aattatattg
     7201 tatctaaagt attaaattat attctcatag gattctagtt attgaactta ggggtggttt
     7261 tcattggtta cttttaggtt actacctttt ttatttgctt cccaccacct caactgacgt
     7321 tcattactat ctatcatttc caaaataaaa tagagctcat ctttcattga ttgagggaat
     7381 tctattgctt gtatgggtag tgtaaaataa gttgtgtaaa cacaaaaagg aataaatccg
     7441 ttatagtaga gttgcaaaac attactagaa agagatttat tcctatgact cagtttacca
     7501 cagaactact taacttccta gcccaaaagc aagatattga tgaatttttc cgtacttctc
     7561 ttgaaacagc tatgaatgat ctgcttcaag cagagttatc agccttttta gggtatgaac
     7621 cttacgataa attaggctat aattctggga atagtcgtaa cggaagctat gcacggaaat
     7681 tcgaaaccaa atatgggact gttcagttga gtattcctag agatcgtaat gggaacttta
     7741 gtccagcttt gcttcccgct tatggacgtc gatatgacca cttggaagag atggttatca
     7801 aactctatca aaccggtgta acgactcgag aaattagtga tatcatcgag cgaatgtatg
     7861 gtcatcacta tagtcctgcc acaatttcta atatctcaaa agcaactcag gagaatgtcg
     7921 ctacttttca tgagcgaagc ttagaagcca attactctgt tttatttctt gacggaacct
     7981 atcttccatt aagacgtgga accgttagta aagaatgtat tcatatcgca cttggcatta
     8041 caccagaagg acagaaggct gttcttggat atgaaatcgc cccaaatgaa aacaatgctt
     8101 cttggtccac cctgttagac aagcttcaaa accaaggaat ccaacaggtt tctcttgtag
     8161 tgaccgatgg cttcaagagg cttgaagaga ttatcaatca ggcttaccca ttagctaaac
     8221 aacaacgttg cttaattcat attagtcgaa atctagctag taaagtgaaa cgagcagata
     8281 gagcggttat tctggagcaa tttaaaacga tttatcgtgc tgaaaattta gaaatggcag
     8341 tgcaagcttt agagaacttt atcgccgaat ggaaaccaaa gtataggaaa gtcatggaaa
     8401 gtctggagaa tacggataat cttttaactt tttatcagtt tccctaccag atttggcata
     8461 gtatttattc gacaaccctc attgagtctc ttaacaaaga aatcaaacgt caaacgaaaa
     8521 agaaggtcct ttttcctaac gaggaggctc tggaacgtta tttagttacc ctgtttgaag
     8581 attataattt caagcaaaat caacgcatcc ataaagggtt tggccaatgt gctgacacac
     8641 ttgaaagctt atttgattaa cattcttcaa ctctacttga gtgtttacac ataattattg
     8701 acagtatcgg gcaattccta tatatgaaaa tattaatact taattattgc aaaaatatat
     8761 aatatgtcta taagatttag aaaggagaaa aaaatgacta ctcaaaacct aaataagtta
     8821 ccaggaacaa ttgcagttcc aatggataaa attcgtatta cgatttactg tccaagtttt
     8881 taaggagaaa aatgattatt caaattttga acagtttacc aagtgattct tttgaattta
     8941 aagatagact tcgtattaca atatactcct aatattcaaa aggttaacgc agactgcact
     9001 atgtttgcgt tttttgttat aattgtataa aaggagttat tttatgattg atactattga
     9061 cataggttct ttaacgaaaa aaattagatt atcaaaaaaa ctttcattaa aagatgttgc
     9121 tggtgattat ctttcggttt cgtttttatc taagtttgaa cgtggcgagt ctgagatttc
     9181 actttctcgt tttctttgta tattggaaaa tttggatgta agtatcgaag aaatttacgg
     9241 aattttatcg aaagataatc ctacaagaac tgaggaatta ctagcaaggg tcagtaaggc
     9301 atttcaacaa aataacatac ctgctctaaa aaaatattat tatgaagaaa tagaaaagtt
     9361 taattcaaca cacaaaaaaa tatttttata taattctatt ttgattgatt catttttaat
     9421 atcgataaca ggtaaaaaaa tgaataaaaa acatattgaa gttatttctg attatctttt
     9481 cgatgtagat caatggggga aaagagagtt agtaatatta ggtaatagta tgtcagcggt
     9541 gcctacaaat acattaaatt tattaataaa agaaattatt tataagacta ctttatttgg
     9601 taataatgag gaaaataaaa aaataaaaat tgatcttatt ttaaacggaa tctcaatatt
     9661 tttagagagg aaagaactaa attatgccaa gttctatatt gatctttttg atacacttac
     9721 cattcctgaa gtttatctct atgagcgagt ggaatataat atattaatag gtacatattg
     9781 gatacttata ggtaaaatag aagtcggcaa gaagaaaatt gaactagctt tggaatccct
     9841 caaaaattta ggtgctgaga atttactgct aatgagagaa aatgaatatg aagaattatt
     9901 gaattctatt atatgacact ttttactaaa aataaaatac tgctgttaca ctagttatat
     9961 agttatacag cagtatttta tttttaatag gagatttatc atggaagaac taattacacc
    10021 aagtgaaaag agaatcatta atagaaaaaa aggggaaata tatgattata tttcatattc
    10081 aaatgctttt gttccttatc aaggttggaa aattcatata tctgctaatt taatagatta
    10141 tcagtctatt ttagataatg tttaccatgt ttgttctatt tttcaaacgc catttaagta
    10201 tatcaataaa atatctgagt tattccgtat tttatcaaaa cacgtttcgc aattagagat
    10261 tggaaaattt ataactatat atcctaaaaa caaagaaact tttttattat tattggaaga
    10321 actatatgat aagataccca aatatactgg agttcaaatt ttgacagata gaagttataa
    10381 agactcagaa ataatttttt atagatatgg agtaatgaat gcacgtttaa ttaataatga
    10441 gcgaccaaaa cttaaattta atggaacctt ttatgaagat ataacggaac catactatac
    10501 atgtccccca tttgttgaag atatcatatt taataaagtt gtagatgact ataatattga
    10561 atctttattc catgatagat atcaaatgga atctattatt cataaatcag gagcaggtaa
    10621 tgtatatatt gcgattgata ctattaatga agaaaaggtt attataaaag aagctagaaa
    10681 aaaagtatat attacagaaa agattttagc aatagatctc cttttaaatg aaaaatgtat
    10741 tctaaaaaaa ttgaaaggta aagtcgatat tccaaattac attgagtgct ttacaattga
    10801 gggaaattta tatcttgttg aggaattcat tgatggacaa agattggata ttttaaagcc
    10861 tgaatataat ttgttgataa aacgaaattc tagcgagtta ggaagatata ataaaaaagt
    10921 aaaaaaaata atttctaatc tatttttaag tttatataaa atccatcagg agggaataat
    10981 attagaggat atatcttcaa gtaatattct tttaacaaat gatgatagag tattttttat
    11041 tgatctcgaa accgcatata ataagaatga tggaattatt gttgagacga caaatgaatg
    11101 ctatcccaaa aacatttctc aaaaaaatga acagcgagat attgttaaaa tgtggtattg
    11161 tataattgat ttattaacta attctactag tcttttaaaa tatgataata caggagtgag
    11221 taccttaaat ttattttata aaatgagttt agagaataat ttacctaaat ctttaagaaa
    11281 aaaatttatt aatgatttta gtatagtgga ctttaagaat acatttataa taaaatttat
    11341 tgaaatgggt ttaaatatag aaaaaatagt tagaatgcaa caagatttaa cagaaactat
    11401 actttcccat aatacttttg aaatttatgg aaaaacaata ttagagtcaa ttgataatta
    11461 taaacatatt agtaatatgg atttaaaatt ttctagcgat cccagtttct cttctcttta
    11521 tgataattgt aataaaagta tagatgactt aatcggaatc gctatacttg ataataattt
    11581 tgaacttttt ttaaattgta atttagatga actactacat aatatgagct actatcaaaa
    11641 atattatcta ctcagacttt tcaatgacac taaaatatgt gatagagtct actttataaa
    11701 ggtcctaaat tcaatcatca aaaatgatat taagtgtatt gatggagtga aatatataaa
    11761 atccaatgag tattttagcc catatttaat aactggtaac tctgggttaa tcattgaact
    11821 tattaagttc agtaaaaata acaatacaat gaagttcgat gaatggatta gaagtttatc
    11881 agaaggaatt agttatacat atgctaaggg aacctcattg tattatggat tagcaggatt
    11941 gggtttggca aatgcttggc tttattatta ttttaaagaa acttcatttc ttaaaacgag
    12001 tattaagatt tgcgaacata tttttgattt ttctattaaa caaaatacaa aaactatatt
    12061 gatagacccg atgtccgaag aaattgatta tacatattca aaaggaatgt tggggcagtt
    12121 gtactttatt aatgagttgc taaatataat taaggaataa cataatgaaa aaatatatac
    12181 taaaatataa actgctaaat cttatacata taatattaat aggatttagt tctgcatttt
    12241 tagttggagc atcagtcaca ctctcaatca tgttaaataa attggttgaa agtgatttta
    12301 aaggcttcct catatggtta ggcattgaat ttggagttta tttgttattt ttggcagata
    12361 catacttaat tagagtaaat cagactaaat taattcaaaa aatgactctt tctctcagag
    12421 atgattatat taacagtcta actagaaaat cgtttagtga atttaaaaat aagactgttg
    12481 gagaacactt gtcaatttta aataacgata taaaaattat cgaagaaagc ggatttgaaa
    12541 gtttttattc attagtttca acagttttca caactttttt ttcaattatt gctctgttta
    12601 gttatgatta tagaatagtg cttttatcta tactacttac tttgatccta acttaccttc
    12661 cacgaagttt tgcccataag atggaaaaag ctatgaaaag attttctata ggtaatgaaa
    12721 catttatttc atcactaaca gatcaattac tgggatatga tacgctatat tattcaaata
    12781 aaaaagagat gttatcaatt aaatgtggag aggtaataaa aaaatttatt tttgaaaaaa
    12841 tagtatttat taaaactagt agcttaattg aaataataat gagtttattt tcaattattt
    12901 ctcaaatgtt agtactactt ttaacaggtt atcttatcat tttaaaacaa gtttcaattg
    12961 gttcaatatc atcagtcgga caaatttccg gaaatatatt taactcatta actacgttta
    13021 atcaattaca ggtatcaata tcatcagtaa atattatatt tgaaaaattt ggagcttttg
    13081 agaagagttc ccattataga tatattgata aagatattga agaaatcaag ttaactaatg
    13141 tcgggtattc cttcaaagat aaggaaattt tcaaaaatat aaattgtagt tttgaaaaag
    13201 gaaaaaatta tgccatagtt ggagagtcag gtagtggaaa atcaacttta ataaatataa
    13261 ttttaggaaa taataagcaa tatagtggaa gtgtaaaata caatgatgta gagatatctg
    13321 atattgaaga atctcaattg tttaaaagcg tttcatatat aggaaatatt actcatattt
    13381 atcatgattc tcttagaaat aatttaacac tttgggataa taaaataaat gaatcagaaa
    13441 ttatcaatat ccttaaacaa gttaatttaa tagatttaat tccacgatta gatgatgaag
    13501 taagtatgtc ttttttatca gaagggcaaa agcaaagatt aggtattgca cgtgcctatc
    13561 ttactaaaac taacgtaata ataatggatg aatctatggc aaatttagat agagataacg
    13621 cttttctaat tgagaaccag ctattaaacg atcctacaag gatgtacatt actgtctctc
    13681 atcacttaca ggaaaaacta ctagatagat ttcatagtat tattacactt taaattgaga
    13741 attcaatgtt actatacaca acaaaaatta atttatacaa aaataatatt tatcaaaagt
    13801 ttggaaatta tttcggggac aaatgatggg acatttcctc tttagacaag taagaaagcc
    13861 tttatttaaa ggctttttta tgtatagtat gatgccccct acatgaattt gtatgaattt
    13921 ttcatattga aaataatcaa aaatgttgaa atataagtta tttttagaag atacttggag
    13981 catttttaaa tataattatt tcaaaatggg gcaaaagtgg ggcaaaaacg aatgactcat
    14041 aaaggtttcc aacttgcttt gaaaaccagg cttgaaaaag gctcgtaaag catcgaaatt
    14101 tagtaaacgt taaaactgat ttacacttat tgaaagcatt tcgtatccaa aatacgggat
    14161 tctttttcca taaaatcaag agaggttggg caaaaactac aagtttaccc ttctgattaa
    14221 aattttaata accaaaaata gcttggaatc aacgtttata atgacgcaat tctaagctat
    14281 tttttatttt taaggtttct tgcctaatct ctttatcatt tggctaacct actccgataa
    14341 cgataatacc ttcaagtatt acaaacaaca aactaaacaa tgctttttta ttcatggtaa
    14401 atacctcttt tcgttttctt atatgatata atatttttaa tatttgtgaa gaaatttccc
    14461 ttataagcaa tttaggaggt gactagaatg aaatatggaa aaatttttaa aaaatttaga
    14521 gaatctcgag gtttatcttt aaaaaatgtt gcaaaatcag gtctttcaag ttcccatctc
    14581 tcaagatttg aaaatgatga ggctgattta accatcagca atttttttag cgttagatgc
    14641 aatacatatg cctatcgaag aatttgttta cgctgtacgt gatttccgca gagatgactt
    14701 taatgaactt ttagaaaaga ttcggtattt agtatcaaat cgtgatatag acggaatgaa
    14761 aaagctatta attagccaaa tggaaaagaa ggataaaaag gaacctttcg cttcatttaa
    14821 cacaattttg attaaaataa gattacagga tttatcagga gaaacttatg taacagacca
    14881 agagattgtt actatcagtg attacttgtt ttctgcggaa tactggggtt attatgaatt
    14941 gctactgttt atgaatacaa tagacgcttt aaatcataac acaatgatga ttttagccaa
    15001 agaaatgtgt catcgtttgg atttttatag agatattcca aataatagac gtttattggc
    15061 aactatgttg ctcaatgctt atatcacctg tattgaacgc aatgaatgga tggacgctct
    15121 ttattttgaa aaacagccaa aatattgtaa cttttcagag actgaaatgt atgaaaaact
    15181 agtgctccat tatgctaata atttatatga tctaaagaaa aataataatc gacatgctgt
    15241 tttggaaatg agaaaatgta ttgctgccac gaaattggta gatagcaatc aaatatctat
    15301 aaaatttgaa aattatttac aaaaagtatt agatgacatg aggtgaattg cgtataaggg
    15361 aaaatattat cctcttctga taaggttata taatgaaact atcaaataaa ggaggtaaaa
    15421 accatggaaa aacttcaggt gattgacctt gaagaacttt tagagtttga tcaagggtat
    15481 gtaattaatg ctagctgtgg tccaagtcat tcttgtggcg gtggtcgata gcttcttccg
    15541 agatgaggag tgattcctca tctcagtttt tagtctggag gataattatg ataaagacaa
    15601 tagaaacaga tataggaaca tattattttg attctgttaa ttttacttta tctttgtcac
    15661 ctatttcaaa acaaagttca ccaactctag attctgttga agatggtgta ttaaaaaagt
    15721 agttataaat atttctaata gttgtaattt atcttgttcg tattgttatg cagatggtgg
    15781 taactatggt atggataatc gtattatgga tttaactact gctgataata ttatccaaga
    15841 gatagcaagt aaaggagtta cacaaatcaa ccgtctcata cttttcgggg gagaaccttt
    15901 tttaaatata gaattattta tatattttat agaaaaatta tctacattat taaatgtagt
    15961 gaaaattgaa acagttacta atggtactgt tttaaataag cgtgttaaag aaatgcttgt
    16021 taaatttcat ccttatttaa ccataagttt agatggacca gaaattgttc atgatagact
    16081 cagaggaaga gggagccatc gaaaaacatt acgttttatt aattatttaa agaatattga
    16141 ttatgaaaat tttgaaatag cctcgacata tactagactt catcaaaaaa atggtctaag
    16201 tagagaagat atctttcaat attttactga tatggatgtg cattttaata taaatgatgt
    16261 ttttactaaa aataaagtgc taattgtgaa agaaatggaa aaaagtttgg ctgaaagaaa
    16321 acagttcata gataaatcca ttcaacatgt aatcaacaac aatgagaagg catttatcag
    16381 tcctatttta tatgatgtat taatatcaat gatatacaag agtacgaatc gtacattttg
    16441 tgatgatatt gacccttcga atacattaac ttatgatgta gatggtagta agaaactatg
    16501 tttcagattt tggggaactc acaacagtcc taaagcggaa tcatttaaca acaaagataa
    16561 ctttgaaaag tgtaaaaact gctggtgtag aggtatgtgc ttggaatgtg ttgccaatgt
    16621 tattgatgga tattcttctg taattagtga agatggggaa tttcttgaat gctctaaacc
    16681 agaactgatg gaatactgta ttaaacagat tatatattta tccaaggaca gagaaaaatt
    16741 atctaggttg gtaaataatt ttagggggtt tatacgctat gcttaggagt tatgtaacga
    16801 aaaaacatct caccttctat tttctagcca tcgtcatcac ttggttagag gccattatca
    16861 cccctgccct tatccagtat atcgtcgcta gttttaccaa ccgccagttg catctcctct
    16921 ggcagatttt gctctggggg attgggggca atctggtgct tgtcctgggc ttggctggga
    16981 agcgctatta ctatgctcgt ttgatgactg actttaaggt tgggataaaa cgcgctattt
    17041 ttcggacttt tttatacagc cgtcagattc ctgatgagga ggtgctgtct gatctggaaa
    17101 atgatgtcca acagttggaa aatagctata tagagccgac cgtcattatc gtatcctcgc
    17161 taggttttac agtcgtttcc atcgcatatg ccctctggac caatttctat ctggggttat
    17221 tgtttatcat cttttactcg gtaccagttt tgtgtagcgg actgggttcg aagcgtttgg
    17281 ataggattgc ggagcaaaaa tccctagcaa atcagaatta tatcgcccgt gtcaacaata
    17341 tgattgcagg tgttgctcct attcgtcatt atcagggcca gaatttgttt ttcaagagat
    17401 tttctaaaga cctagaacag gcgttgcaag aagaagtgtc ctacgaaaag caacggtcac
    17461 tgaacagttt atttatcaac agtatagatg cattttgctc tgtggcgccc attgtgattg
    17521 gcggattcat gacctaccag aactaccttt ctgcggctag ttttgtcggc atttatctgg
    17581 tctcccacaa catcggctac cagtttcaag aactgtccta ctttatcaat acccgcaagt
    17641 ctgccaagtc cctctgcgat aagtatcaag acttgtttgg aaataagttg gctactgaca
    17701 gcatatttga ccaatctgtc tttcctatcc agttggagca ggtcagtgtg gagaaggatg
    17761 gggagaccat tctagctcct tgtgatctga ctatccacgc tggggaaaag attgctatca
    17821 tcggagaaag cggagcgggc aaaaccaccc tgctcaacat cctatacggg gaaatccatc
    17881 ctagtcaggg gcaaattcgt tatcaaggac gggaactaac cagctgtcaa ctctatcagg
    17941 ctggtgccta tatcttgcaa tctagtcatg tttttgacga tttatctgtg gaggaaaaca
    18001 tcgctctggg acaggaaatt gaccagcaaa gaatggataa catcttgcaa gaaacagggc
    18061 tcctcagcct aaaaggcaag gtacccagca accaaacttt atcaggcggt gaaaaacagc
    18121 gccttgaaat cgcccgtgct ctctatcaca agcgacagtt tatcctagca gatgaggtca
    18181 aggctaacct ggacgccaaa aatcaagaaa aaatcaacca gctgctcttt tcacttcctc
    18241 aagctgtggt ggaggtcatt caccactaca ccaaggaaga cttgaagcgc tatgataaag
    18301 tgattcattt gaaaaagtag ttatgccaat agtgtctata gacaaattgt atatctgaaa
    18361 ggctctttgt caactgtctt gagttgatga aaagctaaca tcgagagagg acacaattcg
    18421 ttctctcttt tcttatcttc aaagtgataa gaatgcgttt tttaaagttt tcaaagttcc
    18481 taaaatctca tttagaacta tttggaattg tggatacaaa gcaaccattg actaaataat
    18541 taatgaattg aatgagtatt tagagtattt atttttaact caaaattgat taaaatcttg
    18601 cgtaagccca aagaactggg aagaagcgac cgtgacggat atttggagag aggatttatc
    18661 taaaaaacta gaaaataagt tatttctttc ataacagaaa aagcgagttc aaactcgctt
    18721 tttctattta tcaaataatt ccttattttc aatcaagagt tctagtggag atttgtctct
    18781 tgctacaata aaaccaggtt catattggtt atgaaatgtt cttttctgag aagttggatc
    18841 agtatacaac tcgtctccat cttctgtgta tagttgtttg cctcttgtta ggtaaagtaa
    18901 atcctctaag tactgtccat cagtttctag aaaattttcg atgtatttga cagcctttaa
    18961 gatctcactt actttatcag agtattcatt cgattcaaga acactctttt ctaattcaat
    19021 ctctttacta gttccaaata gttgggttgg agttgcatta aaatattctg ctatcttatc
    19081 caaatttgca aaggtaggat agcttttttg tttttcgtag tcagagatgg attgtttacc
    19141 gattcctaaa tcttccgcaa gttgagtttg acttactcct ttttctatgc gtagtcgtgc
    19201 caaattgggt ccaaaattct gaataataaa ggtcatgata aactcctatg ttgtgtttta
    19261 aacttattct atcacctata aacttacaaa tcaagttttt agttgactgc tcaaaatatt
    19321 ttttaaatga tacaaatagc tcatatgttt aggaatagtg agtgaggagg aatttgagga
    19381 cgagactatg actatgactg atgactattc gaagccttgg agctagaaat tgtgtggaca
    19441 agggcaaggg acgagcctga cgtgaagtca ggcgaagtcc tgcaggctgc cgtccagaca
    19501 atttctagcc aagcaaaagc tggctattct aacagccagc aaaaaggtac acttaggaca
    19561 acgtccaaag aacgacggaa cgagcaaacg ttgatttgac ggtgtttctg aggcctaaaa
    19621 aatctaaaag aaggggggac aattttgttg atttctatac aagatttaag aagcattcaa
    19681 gaacgatgtg aaataggaga attagtacag aggttagatg tcagtattga tagattaacg
    19741 gttatctggg atacagacac tggtccccta agacgaattt tcaaaaatct gaaacaggca
    19801 ataagtacaa gagttgactc atttgaaata catgataacg tgcgagatga tgtctttact
    19861 ttagctaagg attttaatga gtatgattca atcaatatta tatttttcca attatccact
    19921 tatggaggtg aacaattgat tcggattgat ttcaatccta acactttaaa agaatttgat
    19981 ggaatgaaag tatggaggta attaatgtac tttgccagat tgaattcatt gacggtacgt
    20041 ttgtctcgtt ttgatttggc atttgacatt ttcaacaggc ctgaaatcgt taatttgcaa
    20101 catattaaag gtggtgttac ccataaggtc ttctatggta gagggggcga attagagacg
    20161 aaatattggg gttctagcgg tagtaatgta caagttaggt tatatgataa gaataaagaa
    20221 atcattgctc ataagcacga agagaagcta gatttgggtg taaatccgtt ttggtggaga
    20281 ctagagttcc aactcagaac taaagcgatt ggggaggata tggtgcaaga tattatgaat
    20341 cgacttgata atttcggatt ttataagcta gaacatattc gagtggatca aagagccttt
    20401 acaattatct ttctaagcaa tcctgaactg ttatcattag cttttccaaa tttaaaatca
    20461 gacagcatca aaaagaaaaa aacaagagtc cgcaaactat tgagagaaga aacgaatcaa
    20521 tttgcggaag aattaaaaga agtattaata cagaatctcc ctaaattaaa tacagaatta
    20581 caactacttg taggtgagtt tctgacttta gaaaatcaat aaggaggata actatggata
    20641 ataatttaat tagcaacaaa gaattaattg aaatgggcta tcgccctcac actgcaaatg
    20701 atatcatcca tcaggcaaga gaattacttg tatcacgagg ctatacattt tataatcgca
    20761 aacgtttgat ggttgttcca aaaagtgttg taaatgagat tctaggaaca gaggtggcgt
    20821 aatatggcaa gtgttcttta ccgaaagcga ggagatagta atttatggac ctatgaaatt
    20881 cgtaacgaag gaaaaactgt tgctcataat agcggtttta aaacaaaaaa acttgcagag
    20941 tcagaagctg aaccgattct gcaagaactt cgtttaggaa aaagaatttc tagagatatt
    21001 tctcttgccg atctatatca agaatggctt gaactaaaaa ttttaccaag tagtaggtcg
    21061 gaagaaacaa agaaaaaata tcttctccgt aaaaacacaa ttgaaagatt atttggaaat
    21121 aaaaaagtca ctcaaattcg tgcgagtgaa taccaaagaa ttatgaataa gtatgggcaa
    21181 acagttggta gaaattttct tggtagattg aatacgggga ttcatcagag catccaaatg
    21241 gcaattgctg acaaagttct aatagatgat tttacacaac atgtcgagtt gttttcatcc
    21301 aaagaacaac agatgacaga agagaaatat ttacatacag aaaaggacta tctggattta
    21361 cttttagcag taaagagaaa attcgattac caacgttcaa ttgttcctta tatcgtctat
    21421 tttctattaa aaacaggcat gaggtttgga gagttagtag cgttaacttg gaatgaggtt
    21481 gattttgaca gaggattgtt aaaaacatac aggaggtata atactctctc tcataagttt
    21541 gttccaccaa aaaataaaac gtctattcgg atggttccaa tagacgaaga gtgtatcaaa
    21601 attttgcgcc ttttacaaac ggagcaagaa agagcaaaca tggagttagg aatcaaaaat
    21661 cgatatcgaa tgatctttca acattttgga tatattcatt cagttccaga tattgcaagc
    21721 gtcaataaag ctttgagtgt tctcttaaat gagttggaca tttatccaat tatcacgaca
    21781 aaaggagcac gtcacaccta tggaagctac ctctggcaca aagggtttga ccttggagtt
    21841 attgcaaaaa ttctagggca tagagatatt tcaatgttgg tagaagtata tggacacact
    21901 ttagaagaga aaatttttga ggaatttaat caaatcagag atatctggaa agattgctca
    21961 taaaaaaatg tggggcaaac gatggggcaa atgctcttaa gacaagcaaa aaagccttgg
    22021 ttatcaaggc ttttactgtt gaagtttgat gccccctaca gggctcgaac ctgtgaccca
    22081 tggattaaga gtccactgct ctaccaactg agctaaggag gctggatgct gtattggtac
    22141 cgatgatcca cagtttgtat
//
