LOCUS       c00018_JAHDUT0..       13581 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHDUT010000025.1 Streptococcus thermophilus strain Nect13
            Contig_25, whole genome shotgun sequence.
ACCESSION   JAHDUT010000025
VERSION     JAHDUT010000025
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:39:36
            Original ID  :: JAHDUT010000025.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13581
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13581
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[231:8581]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      232..8581
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13581
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13581
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(232..486)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.6e-14,
                     bitscore: 46.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENLNTLDLETLASVEGGGCSWGGAGGATVQGAIGGAIGG
                     AFGGNVVLPVVGSVPGYLAGGVLGGAGGTVAYGATCWWS"
     CDS             complement(737..1138)
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLTV
                     GALAFVVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFPVITFLVLSVEFYTLLTFSDTT
                     DRIVLAVLMLLLILCDFLSYLQVKKYFKQ"
     CDS             complement(1468..1635)
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIVMGLANLFRSLDAVHHTINLLGLTVLLYSL
                     LFKKWVQFQK"
     CDS             complement(1993..2097)
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MAVMSFLDKPIMSFLEKHKATNSVKKKSSVKKKS"
     CDS             complement(2143..2373)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_5"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.2e-18,
                     bitscore: 60.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGVCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             complement(2548..2703)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MKKYLIIFSTIAMIYLYSKVLLSSGNIYQLLLASIGFFFFLFGVY
                     RQYRKN"
     CDS             complement(2729..2929)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_7"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.3e-08,
                     bitscore: 28.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKQLERFKKLDTNALSNVSGQGYGAQCVIGTTGMTIVGAAFFG
                     IAGAGAGFAGGSTAFCYDTAK"
     CDS             complement(2948..3124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_8"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.9e-11,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGLSCDEGMLAVGGLGAVGGPWGA
                     VGGVLVGAALYCF"
     CDS             3380..4111
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="LKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLS
                     AITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNNPYAIIAFVTTHIEFMPQAFGVTAY
                     KYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLSTSDI
                     KHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQ
                     VLPVSRMKIGKIAQIVEERGR"
     CDS             4108..5451
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MMLTTLWLLFLTLLSAGLEIILFLYLMGQKIRLRYFFLLLIFNLA
                     FNFIYNHSSWFIIKFWGEDIYYLLLSFLLSTKTKKPLKIKIFNGLFPDILNNLSLRLIT
                     FFIFPFFNISITDYKSSLLISIPSSIAPLCLSFLFIKLFKESFTILQKQKSNSPIQHII
                     IVANFFMFGYTLLLQSLMYLENTTHSSTLELRKLCIVISLVLFFIMIVFLERNIREMIQ
                     GQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHAYSNLLVTLRLGIDKDDMDIVKEVYD
                     SVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
                     ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFE
                     RGVSNKGRERGIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA"
     CDS             complement(5469..5630)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_11"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.1e-08,
                     bitscore: 27.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNTINNFETLDNHALEQVVGGSGWMDYINGFLKGFGGQRTLPT
                     KDYNIPQA"
     CDS             complement(5645..7012)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEV
                     TVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKVVKKGDTLVQYSETMEASQKEGLQK
                     QLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKTNTE
                     VNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQ
                     YATTPDASVTDQYLSQVNTNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQF
                     LQNAGQQLSSVETQINDTESKINQADVLLTNTLIQSPEDGILHLSQADKKATMAATGTE
                     LAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSA
                     TETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ"
     CDS             complement(7028..8581)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 295.4; E-value:
                     1.5e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_13"
                     /sec_met_domain="TIGR01193 (E-value: 2.7e-245, bitscore:
                     809.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRLTIDVILSY
                     IRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQN
                     SNLFKLVLCSVPIYTLIVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSE
                     KVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQLILNVLILWTGAQLVMGNTISIG
                     QLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIAD
                     GDITVTDLSYKYGFGRDTLTDVCLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGH
                     IDFNGQNISRIDKKTLRQHINYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAE
                     IRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKQ
                     VIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK
                     "
     CDS             complement(8578..9180)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_14"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.5e-46, bitscore:
                     149.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTN
                     KEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDVPYPFIAHVNKDGKLQHYYVIYKST
                     KDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPLIFK
                     QRSLIANIVFASLLVTLINILGSYYLQGILDEYVLIK"
     CDS             complement(9777..9887)
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MTQFTTELLNFGSIISVVGKTTVEIIELFEMVPPQG"
     CDS             complement(10194..11939)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     287.7; E-value: 1.1e-87)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 313.2; E-value: 6e-95)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALTFLLSTTVIKSIIPLVA
                     SYFIDHYLHDMNQAASMILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGTLSSFISAIFIFVTTLYTMMILDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVAIIEKTRALLSDINAKLSESIEGIHIIQAFNQEKRL
                     KKEFDAINEEHLIYASRSISLDSLFLRPAMSLLKLLAYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTAAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSSIINVLMRFYEFQSGRVLI
                     DGVDIRDYSQAELRKNIGLVLQDPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFI
                     DKLPEGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIEHGSHEELLALGGTYHKMYSLQAG
                     AMEGE"
ORIGIN
        1 acatctattt ttacaatcat caacgttttc aagagcgcaa taacggcctt gcccctcttg
       61 aaatgaggaa caaggccgtc gcctaatatt ttattatttc attgtccact tgacagggag
      121 ctattcaata tatgttcaag attatttttt atgtttattt ttattgacct ttttgaaaaa
      181 gatattacct aacaaagcaa caacaaaacc tataataaaa tataccatag attagctcca
      241 ccagcaggtt gctccatagg caacagtacc acctgcacca cctagaacac caccagctag
      301 ataaccagga actgagccta caactggtaa aactacatta cctccaaacg ctcctccgat
      361 agctcctccg atagctcctt gaacagtcgc tccacctgcg cctccccagc tacatccacc
      421 accttcaaca ctagcaagtg tttcgaggtc aagggtgtta aggttttcaa ttgtttgagt
      481 tgccatggca actaccccct aaaattttta tcgtgtgatc tctcaatcac atctttagta
      541 tagcattcaa gtgtctctat cagagctagc gtcccaaaaa gtggctatat gtcccgaatg
      601 gtaattccta aagaacatcc ttcaatcatt ggaaatcttc ctctaatttt cacatattta
      661 cttaatcact ttcttattat aacactttta tgcaaatatc ttatagattg cttacagaat
      721 aatcaagcaa atgcgtttat tgtttaaaat attttttgac ttgaaggtaa gatagaaaat
      781 cacagaggat taacaaaagc attaatacgg ctagtactat acggtctgtg gtatcactga
      841 atgttagtaa tgtgtaaaac tctacactaa gcactagaaa tgtgatgaca ggaaagacaa
      901 tgaaggactg ccgtattgtt aacagattta ctgaatctgg acgcttctta agcatacggt
      961 agagcagtcc attaacaaaa atgactacga aagctagtgc tccgactgtt agccaagttc
     1021 ctggcgagat cttgcttttg tagagagaaa ggctgatact tataaggaaa actgccaacg
     1081 cagcagtgat ggttctaaaa gatcgcaata cactcgaact aatattcttt aacttcatga
     1141 taaaacacct aaactatgaa taacctcagt cagtcttgca aacctaataa gctattacat
     1201 ttaactctat tcctctctgt attttattat acagctgtaa gatttcaagt aagcccttag
     1261 cgattaaatt ctactggaga tgtaatacag tagtgtcatt agtactgata ctttaaatag
     1321 gcgaatatac atatctttgt tttctctatt acaaagatat gcaatcaaat ataatataat
     1381 ctccgctatc attagcaaga ataattttac ttcgggaaca tcaaaaataa gcatttgcaa
     1441 gcatcttacg ttcaaagtga ccaaaggtta cttttgaaac tgtacccact ttttaaaaag
     1501 taagctataa agaagcaccg ttagccctag caagttaatg gtatggtgaa ctgcatccaa
     1561 gcttctaaat agattagcga ggcccattac gatgagaatg gtagccagta aatacggttt
     1621 tgagttttta aacatacttt tctccttaaa gtgtttttag ctagtctgtg cataatctat
     1681 gaattttatt atagattgga agccgataaa aaagtagtga cataaatgtc actacttgtc
     1741 tgaccttata tccttgataa ccgtacacat aagaaagaga aataaacata acccgataag
     1801 atttaggcat tgaagtccaa aattcagttt ttctccaaag ttatgtaagg caacaaggac
     1861 gaagcccata gacatcatta gagacactag gcgttttttg gtcatgatta caaataactc
     1921 ttctcttata tcgaaatttt caatcataat tcacatgcta ttcacagacc agcaattgac
     1981 aagacatttc agttaggatt tcttcttaac ggaagatttc ttcttaacgg aattggtagc
     2041 cttgtgtttt tcaagaaatg acataattgg cttatctaaa aaactcataa cagccatgga
     2101 aaccatccct aaaatataac ttttcaaatc aaacataatc catcaccacc agcatgttgc
     2161 tccataacca acaccaccta cgatagcacc tccagctgct cctgcgacag caccttgcca
     2221 agtacgtgtt ttgataccta gtcgtaaacc attaccaact cctgtagcta ctccttgttt
     2281 agcaaaacct ccccagctac atacaccacc ttcaacacta gcaagtgttt cgaggtcaag
     2341 ggtgttaaag ttttcaattg tttgagttgc catggcaact acctcctaaa atttttatcg
     2401 tgtgatctct caatcacatc tttagtatag catacaagtg tctctatcag agctagcgtc
     2461 ccaaaaagtg gctatatgtc ccgagtagta aaaaaaagac tgaatatcat ttttgattca
     2521 gtccatgtct tattgaaaaa gctttaacta attctttcta tactgcctat agactccaaa
     2581 taaaaagaaa aagaatccta ttgatgctaa caaaagttga tagatatttc ctgatgacaa
     2641 tagtactttg ctatataaat atatcatcgc aatagtcgaa aaaatgatta ggtatttctt
     2701 catttgtatc acctatctca aatgaagatt atttagctgt atcataacaa aatgctgtgc
     2761 taccgcctgc aaatccagct cctgcacctg cgatgccaaa gaaagctgca ccgacaatcg
     2821 tcattccggt agtaccaata acacattgag caccatagcc ttgaccactt acattagaca
     2881 atgcatttgt atccagtttt ttaaatcttt caagttgttt attattcata aattcctccc
     2941 atacaaatta gaaacagtat aaggctgcac ctactaacac cccaccgaca gctccccacg
     3001 ggccacctac tgcaccaagt cctcctactg ccagcatccc ctcatcacag gacaacccac
     3061 cctcaacact agcaagtgtt tcgaggtcga gggtgttaaa gttttcaatt gtttgagttg
     3121 ccatggcaac tacctcctaa aatttttatc gtgtgatctc tcaatcacat ctttagtata
     3181 gcattcaagt gtctctatca gagctagcgt cccaaaaagt ggctatatgt cccgaatggt
     3241 aattcctaat gtatattatt tctaaaattc agaaaaaaaa aaaaatctca ttttatactc
     3301 ataaaaaatt gaaaaaccgt tttctttatg ttacaatttt tcaataaaca gtattcgtca
     3361 taaaagagag gactagacct tgaagattta cctattagaa gataattcta ttcagatggg
     3421 tcgcttggaa gaggctgtgg cacatgaact taaatccttc ggaaaagatc tatcttgtgt
     3481 ccagtctttt gacaaacctg accagttgtt atcagctatc acttctaata caagcgatca
     3541 gattttcttt cttgatattg aaattaaagg tgaagataag aagggacttg atatcgctaa
     3601 aatcatacgt caaaataacc cttatgctat cattgccttt gtcactacac atatagagtt
     3661 catgcctcaa gcttttggcg ttacagccta taaatacatc aataaaacct tagatgaagc
     3721 tagctttaga aaagaaatag gggaaaccat tgctcaagtc ttccctatta acgcaactac
     3781 cacggatgag ttttttctct acaaaacaga gtctcaatta ataaaccttc ctatggatca
     3841 aattctatac ctatccacat cagatatcaa acaccatgtt cacctccaga ctatccatac
     3901 cctcatggat atccgagcaa atctggcaga ctttaaaaag atacacaaaa agctctaccc
     3961 atgccatcgg tcctatatcg tcaatacaga tatgatcatc tctgtcaaca agaccaatta
     4021 tgaagctacc ttaattaatg gtcaagttct accagtatcc cgtatgaaga taggaaagat
     4081 tgcacagatt gttgaggaaa gaggcagatg atgttaacaa cgttatggct actttttctc
     4141 acccttttaa gtgcaggcct agaaattatt cttttccttt atttaatggg acagaagatt
     4201 cgtctgaggt attttttcct actccttatt tttaatttag cctttaattt tatttataac
     4261 cactcttctt ggtttatcat taaattctgg ggtgaggata tctactatct tctgctctcc
     4321 ttccttttat ccactaagac taaaaaacca ttaaaaataa agattttcaa tggtctcttc
     4381 cctgatatcc tcaacaacct tagtttaaga ctgattactt tttttatctt tccttttttt
     4441 aatattagta tcaccgatta taaaagctct ctattaatat ccatcccttc atctatcgca
     4501 cctctttgtc tatcatttct ctttattaaa ttattcaagg agagttttac catacttcaa
     4561 aagcagaaat caaattctcc gattcaacat attattatag ttgctaactt ttttatgttt
     4621 gggtacaccc tactgttaca gtccctcatg tatcttgaaa acactactca ctcttcaact
     4681 ttggagcttc gaaaactctg tattgttatt tcacttgtcc tcttcttcat tatgattgtc
     4741 tttttagaaa gaaacattcg tgaaatgatt caaggacaat tggacttcca gaaaaatctc
     4801 cagctagaga atctctacac ctacaataaa catattgaat gtctctacaa ttctgttcgt
     4861 agttttagac acgcttatag taatctctta gtcacattac gattggggat agataaagac
     4921 gatatggata ttgtcaaaga agtctatgat agtgtgcttc aagaatccga taaacgatta
     4981 aatacaagaa actttgactt agctagactc gttaatattc aggataatac tttgaaaagc
     5041 cttctgtccg caaaagtttt acaagcagaa gaagaaggta ttgaagctca gattagcatc
     5101 ccagaaccca tccacttgat tgggatggag actctggact tcattatcgt cacttctatt
     5161 tttttagata acgctattga aggtgccatt caaactcaaa accctaaaat tactattagc
     5221 ttttgggaag atcattgttc acagctatta tctattagca ataccataag tgaagaaaaa
     5281 acagaaacca aaaccatatt tgaaagaggt gtctccaaca agggacgaga gcgaggcatt
     5341 ggccttgcta atgtcacaga aatcttagat aactatatca atgtaaactt agaaacacag
     5401 agtaacaatt tctcattcac acaacaatta acaataacta aaaaggccta acagcctttt
     5461 ttctatacct aagcttgagg aatgttatag tcttttgttg gaagcgttct ttgccctccg
     5521 aatcctttta ggaaaccatt tatataatcc atccacccac ttccacctac gacttgttca
     5581 agagcgtggt tatcaagtgt ttcaaagtta ttaatcgtat tgttagccat cagtaattct
     5641 cctcctattg gtcttgcaag tttagtaact tgtctttaaa gtaattgaag taggtctttt
     5701 ggtcaataac gcttgtcaca cgaccttcta gaccgtaacg tagattttgg gcttcttttt
     5761 ctgaaatact tgccctagca gttactctaa acacattccc cctttctgtt tccgtggcag
     5821 aattatcaat actctcaagt tttccaataa ttgtggtacc gtgattacca accttatcca
     5881 aggtcagtcg aactgactgg cctttttgca gttttggcac ataatccgaa ttcacataat
     5941 aagtaatggc aacttcctgg gtttgagtca tatcgggata aagctgggcc aactcagttc
     6001 ctgtcgcagc catggttgct tttttatcag cttgactcaa gtgtaagatt ccatcttctg
     6061 gtgactggat gagggtatta gtcagaagga catctgcctg attgatttta ctctcggtat
     6121 cgttaatttg tgtttccact gagctcaatt gctgtcctgc attttgcaag aattgatttt
     6181 ttagagcttc ttttttagtg ctatcactat tgtcataagt tacaactgtg cctgtcccag
     6241 ccttttggat ttctagatta cctatggaag cattcaagct cgaaatattg gtattaactt
     6301 gagataggta ttggtctgtt acactggcat ccggtgtcgt agcatactga ctgttatagg
     6361 catttaaggt tgcctgatga ggattgcctt caggtaaagt cgtttcatga ttggtaatag
     6421 cttgagagag cgcctcatac tctgagacct gagtctgcaa ttgactaatc tggttatcaa
     6481 tagcagaacc ggtattactc gcaattgctg cttggttatt aacctctgta tttgttttag
     6541 ccacacccaa gtcaatatcc tgtgcctgac ttaggtaggt gttaaaagta ctctgataac
     6601 caaactcgtc ttcctgttct tggaaaagat tggttccctg cgttaggcta gattgcaagg
     6661 tcttcaaacc tgattcctgt ctttttaaaa gttctagttg cttttgaagc ccctcttttt
     6721 gcgatgcctc catggtctct gaatactgaa ctaaggtgtc ccctttttta acaaccttat
     6781 tagcaaccag ttgattatct atgatggtat tgtcactggt tgattggatt actgcgataa
     6841 ccttggttgg ctctatactt cctctagacg tgactgtaac ttccttctta gcaaaaaaag
     6901 cgaaaagaaa aaggaaaata actaacaaaa tcaagggagt aatcaaaaca gtagacatat
     6961 tgtggtagcg acgatggtaa aactctgtgc ttttaaacaa ctgtggattc atcgtgtttc
     7021 cttttcctca ctttctaaat aattgataat agaaacctgg ataagacatt aggtcttgat
     7081 gagaacctgt ctccactacg cgtccgtgat caatgactac gatacggtcg gtccgctcag
     7141 cgatactaag cctgtgtgct acaaagatga tcgttttatc ttttagtgct aggaggttat
     7201 caataacctg cttttctgtc aaaacatcca atccgctagt tgcttcatct aagattagta
     7261 caggagattt cgttagtagt gcacgcgcca aagcgatacg ttgcttttgc cctccagaca
     7321 gacctgctcc atcagacagc tctgtctgaa accccatagg catgttttca atatcttgac
     7381 gaatttctgc tatttcacaa gctttcaaaa tatcagcttg cgtaataccc cgtgctgcac
     7441 ctaaagtaag attttctaaa acactaccac taaatatata ggattgctga gggagatagt
     7501 taatatgttg acgaagagtt ttcttgtcta tgcgactaat attttgacca ttaaaatcta
     7561 tgtgcccctt atatggttga taaaaattga ccaacatttt agctagagta gtcttaccag
     7621 atccactgac accaacaaaa ctgatttttt ctccttgtct aatcgtcaaa cagacatcag
     7681 tcaaagtatc acgaccaaaa ccatatttat aagataaatc cgtaacagtg atatctccat
     7741 ccgcaatgcc ttcttgatag gtatcatcac tttgtccaaa ctctgattca atcagataga
     7801 cctcattgag cctagtatta gctaccttag cagactgtaa cttggtttgc aggttaatga
     7861 tattttccaa aggattcgtg aagtaagaaa gcaacatatt aaaagtaatc aattgtccta
     7921 tcgaaatggt atttcccatc accaactgag cacctgtcca gaggataagt acatttaaaa
     7981 taagttgagc accttgtttc aatgatgttt gtagtataga taacttagaa aggcgaaaag
     8041 aattgtctag atagtcaata aactcaccat caatcttttg atagcatact ttttcgctgg
     8101 ttagtgactt tatggtttca atcccattaa tgtcctcaat gatggctgaa ttaaccatag
     8161 cattactctg catgacgtca tgattcattc gctcaaaagg tttcataaag gcaaagacga
     8221 taagggtata aattggaacc gaacaaagaa ctagcttgaa gagattgcta ttttgtatca
     8281 ataacacgcc tcctacgata atcacaatag agaaatcaag gaaaagtgat aatatcgtcg
     8341 aagccagagc atcgataata gagttagcat cactaaaacg tgagataacc tcccctgtac
     8401 gtcttgtggc aaaaaaagac attgggagtt caaagatatg tcgtatgtag gacaagataa
     8461 cgtcaatggt caatcgctga ctcagtatgg ttaagagata atctcttgca aaagtcatca
     8521 tttgttgtaa aacataggtc acaactaatc caattgagat aattcctaag gtagacttca
     8581 tttgattagg acatattcgt ctagaatacc ttgtaaataa taggaaccta aaatatttat
     8641 taaagtaacc aagagactgg caaagacaat attagctatc aaggaccttt gtttaaagat
     8701 caaagggaga aagtcccaga gtccattttt cttatcctta tgtggtttat aactgggttc
     8761 cggtcccata aaaagagtaa cacctgtcca ctctttctca aaacgctctt tagtcatttt
     8821 agttactttt acacttggat cagggtctcc aattatcaga taatccttgg tgcttttata
     8881 aataacataa taatgttgaa gcttcccatc tttattaaca tgagcaataa aaggataagg
     8941 aacatcttcc atctcaaaga gcgacatttc agcctttata gctctcgttt caaagccaat
     9001 ttttttagca gcctctacaa gacctaaggc agttgtccct tctttattgg tcttcgccaa
     9061 ctcacgcaga tgtgctaatg aataatctga accatagtac ttggccactg atgccaaggc
     9121 agcaactcca caatccctca tatctatttg agggacaaaa gtcctacgaa aacgaaacat
     9181 accaaaccct ttcatcacaa attatcatat gattagtatg tcatattttc aggataaaaa
     9241 gagccagcgt cccaaaaagt tgccatacgt cccaaacggt aagaaaaatc ttaaagtcat
     9301 ctccactatt accatttaag ccgtatttgg ggtcatttag gacaagttca ttgaaatcga
     9361 tttcaaagtt atacaatagt tattagaagg aaacattcta aaatagtcct acaagcatac
     9421 gtatttgatc taaccattat tactgtgcca gccctggtat ttccaaagga aaccatgact
     9481 gctgatagcc tcggagccta tctctatcgt atgatgtcat aatttgatta tttttattcc
     9541 gaaaagggat aacattatga aaaacgtcaa tccatatctc aaaaaatcct atcaaaaaag
     9601 gctaaatcag cctcttgaga ttcgattact caattatcgg tttaattttc cttagctttg
     9661 taagtgtatt tgttatcact gtcaatgcta tttttagcgt cactagaggg gttcccttcc
     9721 ttaatgccca ccttatttcc accttgagta attgtgcctt ctatcttttg atttactcaa
     9781 ccttgaggtg gcaccatctc aaaaagctct ataatctcta cagtggtttt tcccactaca
     9841 gaaattatag agccgaagtt aagtagttct gtggtaaact gagtcatagg aataaatctc
     9901 tttctagtaa tgttttgcaa ctctactata acggatttat tcctttttgt gtttacacaa
     9961 cttattttac actacctcaa cgtttgcaag tacctcgaga tcgagtgttt caaatgtatt
    10021 atttgtttgc cttgtcattc taacaacctc ctaaattatt tttagctttt tctctcaagc
    10081 tatgatttta ttatagggtg gtagccaaca aaaaagtagt gacataaatg tcactactcg
    10141 attttgattt ttaagaaatc ttttcgaata tagaagctat ggtctagatt agcttactct
    10201 ccttccatgg cgcctgcttg taggctgtac atcttgtgat aggtgccgcc gagggctagg
    10261 agctcttcgt ggctaccatg ttcaatgatg cggcccttgt ctaagacata gatgcagtta
    10321 gcatcttgga ttgttgatag gcggtgggca atggcaatgg ttgtacggcc ttgacgcatt
    10381 tttgcaagag agttttgaac aatagcctct gtctccgaat caatattggc tgtcgcttca
    10441 tccaaaatca agattttagg ctggctagca acggttctag caaaggctag aagctggcgt
    10501 tgaccggttg agaaacttga accacgttcg gaaactgggg aatcatagcc ttcaggaagt
    10561 ttatcaataa agtgattggc atcgacaaac tcagcagcag ctttaatctc ttcatcagtt
    10621 aaatcttgat acatggcaat attggatttg attgtgccat gatagaggaa ggggtcctga
    10681 aggacaagac caatattctt gcgcagctct gcctgactat aatcacgaat atccacaccg
    10741 tctatgagaa ctcgtcctga ttggaattca tagaatcgca tgagcacgtt gataatagag
    10801 gattttccag agcctgtaga tcccacaaag gcgatggttt cacctttatt gacagagaag
    10861 gaaatattat ccaaaatctg gtgcttgcca tcataggaga aggagacatt ctcaaagcga
    10921 atattcccct cagtaacctt ggcagctgtg tctctctgtt caggctcata ggtacgctcg
    10981 tcaatcaagg caaagacccg acctgctgag accatagagg tttgtagagt cgagaagttt
    11041 tgtgtcactt caatcaaggg atcaaagagg cgattaatat actggataaa ggcatacatg
    11101 gtacctgctg tgatacccag atagatacct cggtagccaa aataggccat gagaacagca
    11161 taagccagga gcttcagtag actcatggct gggcgtagaa agagagaatc cagtgatata
    11221 gaacggctgg cataaatcag gtgttcctca ttaatggcat caaactcttt tttaagacgc
    11281 ttctcctggt taaaggcctg aatgatgtga atcccttcga tactctctga cagtttggca
    11341 tttatatctg aaagcaaggc tctggtcttt tcaatgatgg ccactgattt tttgcgataa
    11401 aggttaacca aaaggacaat cagaggaaga aagaggacaa taagcccggt cagacgaatg
    11461 tccaagatca tcatggtgta aagggtggta acaaagataa agatagccga aataaaacta
    11521 gacagagttc ctgagaacat ctcgctaatg gtctcagtat cattggtcaa gcgggaaacg
    11581 atggaacctg ctggggtctt gtcaaagtaa gacataccca gtttttccat attggcaaag
    11641 gcatctcgac gaatatctct gacaatgcta taggacacac gcgcaaagaa gagatttccc
    11701 agatactgga ctagtgtctg caagaggtag agaccatagt agccaatcag aatcatactt
    11761 gccgcctgat tcatatcatg aagatagtga tcaataaaat aagaggccac caagggaatg
    11821 atactcttga taaccgttgt ggacaagagg aaggtcaaag ctagaaaggt caagaacttg
    11881 taaggcttga gataggtcaa gagacgctta aacacagacc attggttttg attaggcatg
    11941 agcttctcct ccttccattt ctaactgttg agactcatag gtcttggcat accaaccacc
    12001 ttgagctagt aagtcgtcat gacgcccacg ttcaatgata cgaccatctt gcatgaccag
    12061 gatgaggtca gcgtgcacca ccgcactgag acggtgggcg gtaataatag ttgttttgtc
    12121 cttgcgagta tgcttaagat tatcaataat ggcatgttct gtcttagcat caaccgcaga
    12181 taaggagtca tccaaaatca aaatttctgg attcaaaatc atggcccggc tcatagccag
    12241 acgttgtttt tgaccacctg ataggctgac acccttttca ccaatgattg tttcaaagcc
    12301 ttcaggcata tccttgatat catcataaac ttgagctaac ttagtcgctt cttccacctt
    12361 atcaatggag aaatctggat taccaaagcg gatattgtct aaaatagaac tggcaaagag
    12421 aaactggtct tgaggaacat aaccaatcaa gctacgcaag tctgataggc gatagtctcg
    12481 gatgtcatgt ccattcaaat agatggctcc tttattgaca tcgtgctccc gcaagagcaa
    12541 cttgacaaga gccgtctttc ctgagccagt cggtccaacc aaaccaaggg tttgcccctt
    12601 gtccaaggtg aaatgaatat ctcgcaaagt atcctcatcc tcaaaagcaa agcggtcaat
    12661 cgcaaagtct aaacgaccat tttcaatgct tggaagagga taagcgggat cttgaacatc
    12721 tgattcctgc tctaaaagag tctcgatacg ttggtaggac acatttcccc tctgcgtgat
    12781 attaaagagg aagccaatgg ccattagggg ccaaaccagc atgtccaaat aggtaataaa
    12841 ggttaccaaa tttccgaccg ttatctgacc ggcctgaatc ataaaggccc cgacaaggag
    12901 ggtcaaaaca taagatgagc caacaaagag caagaccaaa ggatcaaaaa ggctgtcata
    12961 cttcatggta tgcatattct tttcaaaagt catcttattg gtctcttgga aggactggag
    13021 ctcagcctcc tgatagccaa aagacttggt taccttgata cctgacaccg attcttgtac
    13081 cttattatta agttcagaaa aagctgcctg ggattctcca aaagctttgt gggtcttacg
    13141 tcccaaacga ctagtcgcaa aagccatgaa aggtagaggt aagactgcca tcagggtcat
    13201 ctgccaggaa atgctgaaga acatggtgat taaagtcacc aaggctgtga tagacgcatc
    13261 cacggctgac atgacacccc caccagccaa acgggttaga gagttgatat cattggtggc
    13321 atgggccatg agatcaccag ttcggtactt ttggtaaaaa gaaggcgaca tcttggtaaa
    13381 atgctcaaaa agccgcgaac gcataatctg tcccaagcga taagacgttg ccaagatata
    13441 catccgccaa acatagcgca aatagtacat tcctaaagcc gccaaaagca aataaacgag
    13501 attcaaaagc aagatctgat tggtcaattt tcccgatgtg atagcatcaa tgacccgacc
    13561 cataaccata ggaggaatca g
//
