LOCUS       c00017_JAHRBG0..       18484 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHRBG010000024.1 Streptococcus thermophilus strain Roque89
            Contig_24, whole genome shotgun sequence.
ACCESSION   JAHRBG010000024
VERSION     JAHRBG010000024
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:51:41
            Original ID  :: JAHRBG010000024.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 42429
            Orig. end    :: 60913
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18484
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[52429:55656]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..18484
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18484
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             418..1761
                     /locus_tag="ctg17_50"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIREEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
     CDS             complement(1831..2271)
                     /locus_tag="ctg17_51"
                     /transl_table=11
                     /translation="LVKAEAGDEDTKQTIWGPAHAYTKLAIFDRLAVPGQVYETNEELK
                     KGLINAYKEFLDEYKAVGGKIVQFDDCLWELFVPSNPASFYSDGNGDLAELADEFVAIN
                     NEVVDYTHELGLTLWTHNCRGNYESRSAAEGTYEDIAKKFFG"
     CDS             complement(2434..2664)
                     /locus_tag="ctg17_52"
                     /transl_table=11
                     /translation="MTKSKFQLVGSLLRPADLRKYKDEIEHRDDIQYPFYDALSGYQET
                     ETASIKRIVADQKANGIDILTDGEFGRSMWH"
     CDS             2817..3245
                     /locus_tag="ctg17_53"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESASREIKIWFGE"
     CDS             3247..3537
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 60.7;
                     E-value: 2e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_54"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLTPHTQFFTAD
                     IPAKKDDSIYLYCKMGSRAEFAAGVLKERGYTKVTNLGGLDDMEALGFEIV"
     CDS             3635..4438
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091:glutamine-binding lipoprotein glnH (Score: 159.1;
                     E-value: 1.7e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_55"
                     /transl_table=11
                     /translation="MKKIVYSITMALAIVLLVACQSNSKHNVNTKKVVVATAGNIRPFS
                     YQDNGKLTGYDIEVIRAASKYIKGYDISFKITAWDSIFVGMDSGKFQIAANNLSYTKER
                     ASKYLYSIPIATNPLVLVVPKNSSISKLDDIAGKTTQDDTGTSTAKLVDEWNSKHKATP
                     STIEYSGEDVSKRLLDLSNGEFDYLIFDKVSVETIIKQNRYDFKVIELDTGSNPNNYIL
                     FSNENNELQRQFNQAVKKLYSDGTLKKLSEKYLGGDYIPEKKEMK"
     CDS             4786..5481
                     /NRPS_PKS="Domain: PKS_KR (3-119). E-value: 9.2e-12. Score:
                     37.0. Matches aSDomain: nrpspksdomains_ctg17_56_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     196.5; E-value: 8.7e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_56"
                     /sec_met_domain="adh_short (E-value: 3.1e-35, bitscore:
                     113.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAIAKRLVEDGFRVGVLDYNAETAEKAVAE
                     LSADKAFAVVADVSKQAEVAAAFQKVVDHFGDLNVVINNAGVAPTTPLDTITEEQFQRT
                     FNINVGGVIWGAQAAQAQFKALGHGGKIINATSQAGVVGNPNLTVYGGTKFVVRGITQT
                     LARDLADSGITVNAYAPGIVKTPMMFDISHEVGKMLVKMMSRVCKLLLKILPSNVCQNL
                     KMLQQPLAS"
     aSDomain        4795..5142
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg17_56_PKS_KR.1"
                     /evalue="9.20E-12"
                     /label="ctg17_56_PKS_KR.1"
                     /locus_tag="ctg17_56"
                     /protein_end="119"
                     /protein_start="3"
                     /score="37.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAIAKRLVEDGFRVGVLDYNAETAEKAVAELSA
                     DKAFAVVADVSKQAEVAAAFQKVVDHFGDLNVVINNAGVAPTTPLDTITEEQFQRTFNI
                     NVGGVIWGAQAA"
     aSModule        4795..5142
                     /domains="nrpspksdomains_ctg17_56_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg17_56"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       4801..4863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg17_56_0001"
                     /evalue="9.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg17_56"
                     /protein_end="26"
                     /protein_start="5"
                     /score="11.9"
                     /tool="antismash"
                     /translation="IVTGAGQGIGFAIAKRLVEDG"
     CDS             5937..7769
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 550.4; E-value:
                     9.1e-167)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_57"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDAIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             8176..8517
                     /locus_tag="ctg17_58"
                     /transl_table=11
                     /translation="MDITNFIPSQRQAMLERFQQVEALGLGAVRIELKVANPVGIIYEC
                     YIMSGENYFSDQAVVSFRILYEKDLDRISLDVVDIPGRSSLSNYLQLLEIFEGLQHYLN
                     REFAKVKNT"
     CDS             8777..9223
                     /locus_tag="ctg17_59"
                     /transl_table=11
                     /translation="LASLCLFCFIFLCFITFSLSNKAPSKLTFIYYDEDEFAAFLDSLP
                     LTVASKVIARIREVSAIGIAEAMALKLVRKVDRKKDIFELRINTEGIFARSLFFRLEKA
                     NEEEDNVASPTYIITNSFKKKTNKTPSKELKKAIKRKSNYKNKR"
     CDS             9338..9667
                     /locus_tag="ctg17_60"
                     /transl_table=11
                     /translation="MKEIKLTPLDKVDRNGFLASYLAERSKKEPEILQHYNNEIECIKL
                     SHKIKQLRENINLTQQELADRMGKSQASIGRIENGTTNPTYKTLEEIAAATNTRLVVDF
                     VPIKN"
     CDS             10001..10858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_61"
                     /sec_met_domain="TIGR01716 (E-value: 9.4e-45, bitscore:
                     145.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSIEMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFYYSKNLYELKKNRSNKAILEMKKCIAAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             10918..11718
                     /locus_tag="ctg17_62"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKIISKHFQLNFIDKE"
     CDS             11778..11927
                     /locus_tag="ctg17_63"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGRC
                     PPSV"
     CDS             12010..13227
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_64"
                     /sec_met_domain="PF04055 (E-value: 9.3e-22, bitscore: 70.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3e-10, bitscore: 32.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.8e-12, bitscore:
                     37.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.6e-09, bitscore: 29.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 2.1e-16, bitscore:
                     52.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNVYSIFFNWYNKQGILRNNRNNKLFSLNLATFLALKFMYQFS
                     LKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKIPLKVIQIEVTNKCNLRCMH
                     CYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLLQGLSEIIEEVLKEGMCTTI
                     FTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGV
                     PVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFERNNRLSISDEEFNNAILCIP
                     NIQANCNNVSESTFESFYCGAGNSYVFINSSGDVGFCPTLSSTKFCGGNINEKTLNDIW
                     INSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGSIGSPDIQECKLAYNLTGIK
                     PKSMSL"
     CDS             13224..13967
                     /locus_tag="ctg17_65"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             13974..15146
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg17_66"
                     /transl_table=11
                     /translation="LKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             15399..17075
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 501.8;
                     E-value: 4.1e-152)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_67"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLGTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALTQAVDGPVLIDVPIDYKDNIKLGETILPDEFY"
     CDS             17091..17810
                     /locus_tag="ctg17_68"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRFEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSTPDTKFAEVATHQPEYESDNISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(17862..18482)
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 182.9; E-value: 1.6e-55)"
                     /gene_kind="other"
                     /locus_tag="ctg17_69"
                     /transl_table=11
                     /translation="SGAYIPLARKLFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQFDK
                     KSLPYRALKNHWRLFQKDSCKLSLNSFYSKTFRQTLAPHEVVKKTLVFSKELTDYYTLY
                     QLLLFHFQEKRVGEFFDLIEENRSKVNHYFQTVFRTFLRHKQYIQNALETDYSNAKLEA
                     TNKLIKDIKRLGFGFRNFINFKKRVFITLNIHKKRTYPVLSRC"
ORIGIN
        1 ttgtttcaaa tgccgtagag catacaccca gtggcagtca gttgctcctg accgctaggg
       61 tagaagaaga tgaattcaag tttatatgcc ttgattctgg tcctggattt tcccttgaat
      121 ctcttgaaaa cgctactcag ctattttatc aagaggataa aagcagacag agtcgcaatc
      181 atagtggcct tggtctgact attgccaatg atattattcg tttacactat ggtagtcttt
      241 ctcttgcaaa tgacaatggc acgggtagtg ctaaagtgac tatcatttta ccccttttaa
      301 atacagatga ctcctagtcg ccagatgagg agttttttgc tatactacta agagtaaaaa
      361 tgaagaaaga tttgtgggag caggatttca tcttgtttcc gaagaggtat tagtgtcatg
      421 tctcaatcaa aagcagatta tattaacgtg attggagctg gtttggccgg atccgaggcg
      481 gcttatcaga ttgccaaacg tggtattcca gtaaaacttt atgaaatgcg tggggtcaaa
      541 gcaacaccac agcataagac aacaaatttt gcagaattgg tttgctctaa ctctttccgt
      601 ggagatagct tgaccaatgc tgtagggctt ctaaaagaag aaatgcgtcg tttggactct
      661 atcattatgc gtaatggaga agctcaccgt gtgccagcag gtggtgccat ggcggtggac
      721 cgtgaaggct atgcagaagc agtgacagct gaaattgaaa gtcatccctt aattgaagtt
      781 atccgtgaag aaatcacaga aattcctgat gatgctatta cagttattgc ttcaggtccc
      841 ctaacttctg atgctttagc tgaaaagatt catgagctta acggtggaga cgggttctat
      901 ttctatgatg ccgctgcacc aatcgttgat aaagcaacta tcgacatgaa caaggtttac
      961 cttaagtcac gctatgacaa gggtgaagca gcttatctaa actgtccaat gaccaaggaa
     1021 gagttcatgg cctttcatga ggccttgact acagctgaag aagctccttt gaattctttt
     1081 gaaaaagaaa agtatttcga agggtgtatg cctatcgagg ttatggctaa acgtggtatt
     1141 aaaacaatgc tctacggtcc tatgaaacca gttggtttgg agtatcctga agattatatg
     1201 ggtccacgtg atggtgactt caagacacct tatgcggttg ttcagcttcg tcaggacaat
     1261 gcggctggta gcctctacaa tatcgttggt ttccaaaccc acctcaaatg gggagagcaa
     1321 aaacgtgtct tccaaatgat tccaggtctt gaaaatgcag aatttgttcg ttatggggta
     1381 atgcaccgta actcttacat ggattcgcca aacttgctta aacagacctt ccaatcaaaa
     1441 tcaaacccta atttgttctt tgctggacaa atgactggtg ttgaaggtta tgttgaatca
     1501 gctgcctcag gtttggttgc tggaatcaat gcagcccgtc tctttaaggg tgaagatgaa
     1561 gttattttcc ctcatacaac agcaatcggt agccttccat attatgtgac acatgctgaa
     1621 agcaaacatt tccaaccaat gaatgttaac tttggtatta tcaaagaatt agaaggccca
     1681 cgtattcgtg acaagaaaga gcgttatgaa aaaatcgcag aaagagctct taaggatttg
     1741 caaactttta tagatgcttg atgctaacat aaaaagccct cacaagagtg aaggcttttc
     1801 gttttagaga ggagcgaata gaaatatcga ttagccaaag aatttcttag cgatgtcttc
     1861 gtaagttcct tcagcagcag aacggctttc ataattacca cgacagttgt gtgtccaaag
     1921 cgttaaacca agttcgtgag tatagtcaac aacctcgtta ttgatagcaa caaattcatc
     1981 ggccaattct gccaaatcac cattgccgtc tgagtagaaa cttgcagggt ttgatgggac
     2041 aaaaagttcc cagaggcagt cgtcaaattg aacgatttta ccaccaacag ccttgtattc
     2101 atccaagaat tctttatagg cattaatcaa accttttttg agttcttcgt ttgtttcata
     2161 gacttgtcca ggaacagcca atcgatcaaa gatagcaagt ttagtgtagg catgagcagg
     2221 tccccagata gtttgtttgg tatcttcatc accagcttca gccttaacca atttgtaaat
     2281 atctaggtag tggtgttttt tacctgagag aggctcagtg atacgaatac cgatatcttt
     2341 acgtgtttca tattgaccac catcatggtc ttaaaaagta taaccatgct cagcaatgta
     2401 gcgttcaata cctttgagtc cccagacaaa gtcctagtgc cacatagaac gtccaaactc
     2461 cccatcggta aggatgtcaa ttccgttagc tttttggtca gccacaattc gcttaataga
     2521 tgcagtttca gtttcttgat aaccagaaag ggcatcatag aaaggatact ggatgtcgtc
     2581 acgatgctcg atttcgtcct tgtatttacg gagatccgca ggacgaagaa gagaaccgac
     2641 taattggaat ttagattttg tcattaaatt tacctcgaaa tgtctattta catctatatt
     2701 atttcttatg ggaactaatg aaaaatagtt aatttcttgc tgtggatata attttagact
     2761 atataaggtt tagctctgca aaatgatact tcttatgata aaatggaaag aaaacgatga
     2821 aggttgggaa tatgcaaaaa acattcttta ttattaaacc agatgctgtt aaacgccatc
     2881 taattggtca agtgcttgat cgaattgagc gacgtggctt cgttattgag cgtatggaga
     2941 tgctgatgct tgacgaagaa cgtcttaaag aacattatgc ccaattggct gataaacctt
     3001 ttttccctag tatttctgaa ttcatgatga gtggtccagc agttattggt attatgtccg
     3061 gcccaggtgt tattaagtca tggcgtgata tgatgggagc aactaatcct ggggatgctg
     3121 ctcctggaac gattcgtgga gactttgcaa cagcaccaga tggtgacatg attccaaata
     3181 tcgttcatgg ctctgattca gaagaatctg cgtctcgaga aattaagatt tggtttggtg
     3241 agtaggatgg atatagcaca gattcaatca gaattagctc aggatggact attaattgat
     3301 gtcaggactc cagaagaata cgcagaaggt catgttaagg atgctttatt aacacctcac
     3361 acgcagtttt tcacagctga cattccagct aaaaaagacg attcaattta tctttattgt
     3421 aaaatgggat ctcgtgctga atttgctgca ggagtactga aagaacgagg atatactaag
     3481 gtgactaatc taggtggctt ggacgatatg gaagcactag gttttgaaat tgtttgatag
     3541 atattgttta tcagttaata aaaaatctgt aatttacact gcttcattct aatgataaaa
     3601 taatttccaa ttttaagatt ttggaggttt tagaatgaaa aaaatagttt atagtatcac
     3661 aatggcttta gccatcgttt tattagttgc ttgtcaatct aatagtaagc ataatgttaa
     3721 cacaaaaaag gtagtggtag cgactgctgg taatataaga ccattttctt atcaagacaa
     3781 tggaaaatta acaggttatg atattgaggt cattagagcg gcaagtaagt atattaaagg
     3841 atatgacatt tcgtttaaaa taactgcctg ggattccatt tttgttggta tggatagtgg
     3901 aaagtttcaa attgcagcaa ataatctctc ttatactaaa gagagagcaa gtaaatatct
     3961 gtattctatt ccgattgcga ccaatccttt agtcttagtt gttccaaaga attctagtat
     4021 ttctaaacta gacgatattg cgggaaagac aacgcaagac gatacaggga cttctacagc
     4081 gaaattagtt gatgaatgga atagtaagca taaagcgact ccttcaacta ttgagtattc
     4141 aggtgaagat gtctctaaac gtttacttga tctatccaat ggtgagtttg actacttaat
     4201 ttttgataaa gtttcagtag aaacaattat taaacagaat agatatgatt ttaaagttat
     4261 tgaactagac actggatcaa atcctaataa ttatatctta ttttcgaacg aaaacaatga
     4321 attacaaaga cagtttaacc aagccgttaa aaagctctat tcagatggaa ctttgaaaaa
     4381 actaagtgaa aaatatcttg gaggagatta tattccagaa aagaaggaaa tgaagtaggc
     4441 ttatcttaat ccatcaacta ttttattgtt gcgtttaggg attatctcga gtatctaata
     4501 gagacttttc ttactcggga aatttgagac tcatatctga atcttgagta gggactatca
     4561 aaaagacttt gtcatcattc aaagactacc ttaaggtggt cttatttgct ttcaaaaagc
     4621 atgacaaatt attaacaacg ctttcataaa gtggtaagat tctaaatgag ttaagacaaa
     4681 gcctatgaaa atgactttgc cagaacttga ctaacttagc gtattccaat tgagataagg
     4741 cttcttacta agcttgtgac tccaattggt agagggggat ttcgtatgtc aaaagttgct
     4801 attgttacag gtgcaggtca aggtattggt tttgcgattg caaaacgttt ggttgaagat
     4861 ggttttagag tcggagtatt ggactacaac gctgaaactg cagaaaaagc tgttgctgaa
     4921 ttgtcagcag ataaagcatt tgcagttgta gctgatgtat ctaaacaagc tgaagtagca
     4981 gctgctttcc aaaaagttgt tgatcacttt ggtgatttga atgttgttat taataatgcc
     5041 ggtgtggctc caacaacacc tctcgataca attactgaag aacagttcca acgtacattt
     5101 aacatcaatg tcggtggtgt tatctggggt gctcaagctg cacaagcaca atttaaagca
     5161 cttggtcatg gtggtaaaat tatcaatgca acttctcaag ctggtgtcgt tggtaaccct
     5221 aacttaactg tatatggtgg aactaaattc gtagttcgtg gtattactca aactttggcg
     5281 cgtgacttag ctgattcagg tataactgta aatgcttatg caccaggtat cgttaagact
     5341 ccaatgatgt ttgacatttc ccacgaagtt ggtaaaatgc tggtaaagat gatgagtagg
     5401 gtatgcaaac ttttgctaaa gatattaccc tcaaacgttt gtcagaacct gaagatgttg
     5461 cagcagccgt tagcttccta gctggacctg actcaaacta catcacaggt caaacaacca
     5521 tcgttgatgg tggtatgcaa ttccattaag gttaaaaggg agagcgaatg gctctctttt
     5581 tttgcttgat aaaacataat gtttctgata atatagttat aaataattat gtttttaaag
     5641 gtggattccc atatcagaca tcttacacta tattgctgag cacccgtttt ttagtcttat
     5701 tctattggga attattgtac taacccttgg tttagctcca ttttcaagta gttcaataga
     5761 gaacaagcgt tcagctatta ttaataagca ctacaatgat aattttaaga aataagaagg
     5821 attaaatgca gtcataaagc agatattaga gataggcaaa tgcctatctt ttttgtataa
     5881 taggaggtaa cggttcgttt tttaacaatc acaagtaaga actaggaaag aataaaatgc
     5941 caaatattga agaattaaaa caaagacagg agaagattcg caacttctcg attattgctc
     6001 atattgacca tggtaaatca acgcttgctg accgtatctt ggaaaagact gagactgtat
     6061 caagtcgtga gatgcaggca caactccttg atagtatgga tcttgagcgc gaacgtggta
     6121 tcactatcaa actgaatgcc attgagctta actacaaagc taaagacggc gagacttata
     6181 ttttccacct tatcgacaca ccgggacatg tggactttac ttatgaggtg tcacgttccc
     6241 ttgccgcctg tgagggtgct atcttggtgg tagatgcagc tcaagggatt gaagcacaaa
     6301 cacttgccaa tgtttacttg gcacttgata atgacttgga aatcttacca gttatcaata
     6361 aaatcgacct tccagcggca gatcctgagc gtgtacgtac agagattgaa gatgttatcg
     6421 gattagatgc ctcggaagct gtgcttgcat cagctaaggc tggcattggt atcgaagaga
     6481 ttctcgaaca aattgttgag aaagttcctg cgccccaagg tgatgtggaa gcacctctcc
     6541 aagcccttat ctttgactct gtttatgatg cgtatcgtgg cgtcatactc caagtgcgtg
     6601 tggttaacgg aatggttaaa acgggcgata agattcaaat gatgtctaat ggcaagacct
     6661 ttgacgttac tgaggttggt attttcactc ctaaagctgt tggccgtgac taccttgcga
     6721 ctggagatgt tggttatgta gcagcttcaa ttaagacagt tgcggatact cgtgtcggtg
     6781 atacagtgac acttgcggat aatccagccg cagaaccact tcatggttat aagcaaatga
     6841 acccaatggt ctttgctggt ctttatccaa ttgagtcaaa taaatataac gacttgcgtg
     6901 aggctcttga aaagctccaa ttgaatgatg ccagtcttca atttgagcct gaaacgtctc
     6961 aagcccttgg ttttggtttc cgttgtggtt tcttgggcct tcttcacatg gatgttatcc
     7021 aagagcgttt ggaacgtgag tttaacatcg atctcatcat gactgcacca tcagtagttt
     7081 accatgttaa cactactgac ggtgaaatgc ttgaagtgtc caacccatct gaatttccag
     7141 atcctacacg tattgatgcc attgaagagc cttatgtcaa agctcaaatt atggttcctc
     7201 aagagtatgt tggtgctgtt atggagttgg cgcaacgtaa acgtggtgat tttgaaacca
     7261 tggaatatat tgatgataat cgtgttaacg ttatctatca aattccactt gctgaaatcg
     7321 tctttgactt ctttgataaa ttgaagtcat caactcgtgg ttatgcaagt tttgactatg
     7381 aattgtcaga gtaccgtcgt tcacaattgg tgaaaatgga tattctcctt aatggtgata
     7441 aggtcgatgc ccttagcttt attgtccata gagaatttgc ctacgaacgt ggaaaactta
     7501 tcgttgataa acttaagaaa attattccac gtcaacaatt tgaagttcct atccaagcgg
     7561 ctattggtca aaaaattgtt gcccgtacag atatcaaagc tcttcgtaaa aacgtcttgg
     7621 ctaaatgtta cggtggtgac gtttcacgta aacgtaaact cctcgaaaaa caaaaagctg
     7681 gtaagaaacg tatgaaagcc attggttcgg tggaggtacc acaagaagcc ttcttgtctg
     7741 tgctttcaat ggacgaagat gagaaataag aatgatagtc agaatgtgat gttctggcta
     7801 ttttagtaaa aagttatgat aaagaggatt ttaaaattta ccttctcaaa gtgtggaagg
     7861 atttatgcta cgatcatact aaatactttt ctttttaggg aatggcgata caaagcatgt
     7921 agcagaatta tagactgacc taaaagcaga taaggtaact tccaatgaga tttttggtag
     7981 tcgtcaacaa tatgttgtac ttagtcatgt agaacacact tactacatta cgataaacac
     8041 tataaaatca gactttagag aatataaaga agctagatga ggattcatgg ggggtagtct
     8101 tatcaggaat cccttcgcaa gcatttttct cagctttagg ctataatata caaaaggaaa
     8161 gtcgggaggg ccactatgga tatcacaaat tttattccta gtcagcgaca ggctatgttg
     8221 gaacgttttc agcaagtgga ggccttgggc ttaggcgcag ttcgtattga gttgaaggtt
     8281 gcgaatcctg ttggcatcat ttatgagtgc tacattatgt caggagagaa ttatttttct
     8341 gatcaagcag tggtatcctt ccgtattctt tacgaaaagg acttggaccg catttctttg
     8401 gatgtggtag atatccctgg tcgctcaagt ttgtctaatt atctccagtt actagagatt
     8461 tttgaaggct tgcaacatta tcttaatcga gagtttgcta aggtaaaaaa tacataaaca
     8521 tctgattgta atcaggtgtt tctttttgtg ctggaagttc aaaatttcac aatagtcaac
     8581 ctccatttga taataattcc accaatcgtt acgattttcg tcgaagaagt aactagtagg
     8641 aatatgtgca aacgtctcag caattaaccg aatttgcaaa gggttcaaaa aaccaactgc
     8701 ttggaaccgc tttaaataca taaaatatcg tttagcgatt agttctcctg gctcacctga
     8761 tacattctta cgttctttgg ctagtttatg ccttttttgc ttcatttttt tatgtttcat
     8821 aactttttcc ttaagtaata aagccccctc taaactaacc tttatttatt atgacgaaga
     8881 cgaatttgca gcgtttttag attccctccc cttaactgta gcgtcaaagg ttatcgcaag
     8941 gatacgagag gtttctgcta tcggtatagc agaagccatg gctctaaagt tagtcagaaa
     9001 agtagataga aaaaaagata tctttgagct tagaattaat acggaaggca ttttcgcccg
     9061 ttcattattt ttccgtttag aaaaagctaa cgaagaagaa gacaatgtgg cttcacctac
     9121 ttatatcatc acaaactcct ttaagaaaaa aacaaataaa acaccatcta aggaattgaa
     9181 gaaagctatc aaacgaaaat cgaactataa gaacaagcga tgacacaaac tggattctcg
     9241 caatccagtt ttaagggctg aaaaagattc aacctttaaa actggactgt aaagtttagt
     9301 atggatattg actatatttt attaaggaga gatgcacatg aaggaaatca aacttacacc
     9361 acttgataaa gtggatagaa acgggtttct tgcttcatac ttggcagaaa ggagtaaaaa
     9421 ggaacctgaa attctacagc actataacaa tgaaatcgag tgtataaagc tatcgcataa
     9481 aattaaacaa ttaagagaga atatcaattt aactcagcaa gaacttgctg atcgtatggg
     9541 aaaaagtcag gctagtatcg gacgtataga gaatggcacc actaatccaa catataaaac
     9601 attggaagaa attgccgctg caaccaatac tagattagtt gttgactttg ttccaataaa
     9661 gaactagttt ttgtatacac tcaaaaagct ctataatctc tatagtggtt ttacctatta
     9721 cagaaatcat agagtctttt ttatattata cccttattag agaacaacat cataccttaa
     9781 ctacaccaca aaagttagac atcgaaagtc taacttttgt ggtgtcttta ttttctattt
     9841 gtttagccaa cagcaattac aataatgctt tcaaaaatta gaagtaagat agctaaaaaa
     9901 ctttctttat tcatagaaat taacctccta tctcactata tgatataata cttttaagtt
     9961 tatctgggaa attctcgtat atgcaaaaga ggtgcttttt atgaaagatt atggaaaatt
    10021 atttaagaaa tttagagagt ctaggggatt agtcttaaaa gatatcgcaa agttaggcgt
    10081 atcagtatct catatttccc gctttgaacg tgaaaataca gatttgacaa ttagtaagtt
    10141 tatgtcagct ttaaatgcga taaatatgcc tattgatgag tttatgtatg cagcaaacga
    10201 ctttcagaga gatgagttta atgaaatctt agaaaagatt agtttatttg tttcagcaag
    10261 gaacgtgtca ggtatggaaa agttattaat ctctcaagta gaaaaaatcg aaaagcgtga
    10321 gactttttat actctaaata ctattttaat aaaaattcgt ttacaggact tatcagacaa
    10381 aagttactat gatgaatctg atatccaata tttatcagac tacctattct ctgtagaata
    10441 ttggggttgt tacgaactac tgttatttgc gaatactgta gatgtattga atcatcaaac
    10501 aatgatgctt ttatcaatag aaatgtgtaa acgttcagaa ttttacaagg atttaccaaa
    10561 ctaccgaagg ttacactcaa caatgctatt aaattgttat atcataagta ttgaaagaga
    10621 tgagtatatt gatgcgttgt attttgaaaa acagttaaat catagttgtt ttacggaaac
    10681 tgagatttac gagaaattag tgttttatta ttcaaaaaat ttatatgaat taaagaagaa
    10741 taggagcaat aaagctattc tagaaatgaa gaagtgtatt gctgcaatga agctggctaa
    10801 tagtgagaat ttagctataa aatttgaaaa tcatttatct ggagtgttaa aaatgtagtt
    10861 ggatttgtgt atatggtata aattatcagt gtcaaaatta aatgatatat tattgatatg
    10921 agaattatta aatttcctga acagatttca gaagatatca ttcattatac gtttctagat
    10981 gatattatct cttataattg tgaaaagtgt agaggatctt gttgtcatgt gaataattct
    11041 ttattacttg atgcaaagac agcaagtttt ctaaaacgca cgtatcttaa agattttatt
    11101 gttagtgatg atagtgtttc attgttgagt tgtggtaaaa agtgctggtt tcattctgaa
    11161 ttgggttgta cgataaatga tttaggcttg aacaagccat taacttgtga attatatcct
    11221 tttcatatta agaaaattca gaacttctat attgtttctt ttactccttg tccgacattt
    11281 caactgaacc ttggtgaggg gcagaggtac aaggatatag aggatgtagt tttacgatat
    11341 attaaaactg gggtgccagt ttttagtccg tctttgcatg tttcagagga aaggctgaaa
    11401 tatgagattg agtatcaaaa caattttaaa aacactttat cagagtatta tcgaacaaag
    11461 actgccgatg gcactacaga gtttaaagaa tatgaaaaat ggtatatata ttatttagat
    11521 tttagatggg gaagtatacc cttatcttat acaagttcac aagcaaatca attttggaat
    11581 ctttacaaga gagtttgtga agatgtttat aaaaaaatat catatatacg aacagataac
    11641 atatacttta ttattgcaaa tcagtttaat aagataattt caaagcattt tcagctaaat
    11701 tttatagata aagaatgatt tctatgattt gttatgggta cttattgatt cttaaataaa
    11761 taatggagga tattacgatg caagttagtg atgctattgc acaaattgaa ttagcagaag
    11821 aagaagttgt ttctagcggt ctatctattg acattatgga aattaaacct tctgttgcta
    11881 cagagttgat tgatggactc aaaggtcgtt gcccaccgtc tgtctaatag aactgattgt
    11941 aggattagag tctatttcta atcctttggt ttttatatta atatttttgg aagattgcag
    12001 ggaattaata tgacgagcaa tgtttactcg atttttttta attggtacaa taagcaagga
    12061 atactcagga ataataggaa taataaacta ttttcattaa atttagctac atttttagct
    12121 ttaaaattta tgtaccaatt ttcattgaaa aagttttctg attcaaagag tcaggtaata
    12181 aaaaatgtta tagattttct aaataacaat gaaatatcac tctctaagac caacactaaa
    12241 attgttgaat tttcaacgaa aataccatta aaagtgatac agattgaggt cacgaacaaa
    12301 tgtaacctaa gatgtatgca ttgttattta cctgattatt caaaggagct cgatagaaag
    12361 aaaatttcaa gtatagtata tgaagctaag cagctaggag taatggatgt tgatttcact
    12421 ggaggcgaac cattattatt acagggatta agtgaaatta tcgaggaagt attaaaagag
    12481 ggaatgtgta caacaatttt tacaaatgct gtatatattc ctgaagattt taaaatattg
    12541 attcaaagat atgatggtat aagactaaaa gttagtttag atggttggaa tgaaacaata
    12601 catgattcaa ttagaggaag aggtacattt aagagaacaa ttaagaatat tgaatatttt
    12661 aggagtttag gagtacctgt tactgttaat gttgttttga ataacaagaa tattagtgga
    12721 gtgaagtatt ttttggagtt gtttgatcga ttagatgtga aatatgcttt tgataggttt
    12781 ttaccttttg aaaggaataa tcgactatca attagtgatg aagaattcaa taatgctatt
    12841 ttgtgtattc ccaatattca agcaaattgt aataatgtat ccgaatccac atttgaatca
    12901 ttttattgtg gtgctggcaa ttcttatgtg tttataaatt cgtcaggtga tgttggattt
    12961 tgtccgacat tatcctccac taaattttgt ggaggtaaca ttaatgaaaa gactttaaat
    13021 gatatttgga ttaattcgaa gttcttcaat catattcgaa atgtacgatg taagtattat
    13081 aatgaatgcc ctgcaaatta tgtttgtcaa ggtgggtgta gaagtcgagc tcagtttttc
    13141 ggaggttcta ttgggagtcc cgatatacag gagtgcaagt tagcatataa tttaactggg
    13201 attaagccaa agtcaatgag tttatgaaaa tattatctat tatttatgat ggtggaagta
    13261 gaattccagg agcgagattt gctcccacaa aatattatca agaagcgatg ttatatgata
    13321 ggaaagattc tgatataatt acaattaatt taggtaatca agatttattt tctattgatt
    13381 tagaaagtct aagtcgaact attgctgaat ctaaagttca gattgcttta ggaggagatc
    13441 attcagttac ttatctatta gcaaaggcca ctgttcgaga gggagcatat ttaattgttt
    13501 tagatgctca tttagattac ttcaaagact ttgaaagtgt tgtaaaaaat tggaattttt
    13561 taagtttttt aaccgatatt tttgaaaaaa taattatcat tggggaaagg aattttgagt
    13621 ttcctagttc atttgataat aaaataatca tcctctcaat ggaggagtat tggttaaata
    13681 agagtagagt tttgaaaaag ttagatagtt atattgatga gtcaaaagat atttacttat
    13741 caatagacat tgatgttttg gatccatctg tttttgattc agtatcatat cctattattg
    13801 gaggatttca aatgaacgat tttcttggaa taatttccaa aattttatgt tctgataagg
    13861 tatatttttg tgatatagtt gagtacaatc cgatggttgg aagtgataat gctcacattt
    13921 tttaccaaat gattcaattt gttaaatcaa aattaaggag gatataggaa atattgaaaa
    13981 taaaaaaata tgcagcattg agtatttatt ttaatcgttt ctcatcgtta atctcagagt
    14041 atggttatac tatcttgatc aacattctat tgtctagaat ttctgtgcaa ttagttatgt
    14101 atttttgggt ggtaaagtgt ttagctgcaa tagttacaaa taggattaat atctcaaata
    14161 gtaaactgag cagaaaatac ctgcttattc tgttagaaat tacaaaggca atcttacttt
    14221 tcttactagg ttttggatta aaccatataa ttgtcctatt agttgtattc ataattgagg
    14281 ttgtcaatgt attgttttcc agtttattat atagttgtgt accaattatt atagacaagg
    14341 attcattgat taagtttaac gctaggtata caagcattgg ttcagtatct tattttttag
    14401 caccgttgtt tgttggttta tttattaata aaagtcactt tttattgttt gcagtttatg
    14461 ctcttctttt gatagtggga gctactagtc ttttattttt accaaatatt tcgactttaa
    14521 atttgaaaga agaaagaaaa aaacaaaatt taaacattac attatttaac attctgagat
    14581 ccaaaaaaat tgcattagtt ctattatctg gagttattgt gggatcaatt ggagttgttt
    14641 atgatactta tgaagttgtt tatttaacaa agtatctcgg tattagtgat tctatgtatt
    14701 ccttttcctt atcattttta gcagtttcat tcttagtaat gagcttcctt cttagcttcg
    14761 tgaaacaaat aagttctcat atgaaagctt tcgccttagg tctttcattt tatgttctat
    14821 atctactttt atttagtaca tcttcgaaca tttatacagt actaatgagt tatgtttttc
    14881 tagcgatagg tcagacaatg atggggataa tcgaaaccaa ttattttcag ttgtcactta
    14941 acatgaaaga attacagaaa ctatatattt actcggagac cttacattct gtattttcag
    15001 gcattgctgt tttagtaata ggaagttttg cctttttaag tagtcatctt gttttagttt
    15061 tcagaagtct tgctgttttt gctctgttta ttcttctgtg ttattgtgtg tttgtaaacc
    15121 tcaaaaaact aagcattgat aagtaatatt tataaatcag aaaacaagca aatgagatag
    15181 ttaatttata aagtagacaa acgctatttt gagtgtttgt cttttttagt cacctagtct
    15241 gccttttttc acaagattgt ctgaaaactg tgctataatg ataacagaat tgtgaattga
    15301 tgaaagtttg tgaaaaaacg agcagacttt gacactttgt gacttatact tgaaaggaaa
    15361 gttggctcta ccattttagg gctagaagga ctgtgttcat gtcagaagaa aagcaattgt
    15421 atggtgcaga tttagtggtt gatagtttga tcaaccatga tgttgagtat gtctttggga
    15481 ttccaggcgc aaaaatcgat agggtttttg ataccttgga agataaggga cctgaattga
    15541 ttgttgcccg tcatgagcaa aatgctgctt ttatggctca aggtgttgga cgtattactg
    15601 ggaaaccagg tgtagtattg ggaacatctg gtccaggtgt ctccaatttg gctactggtt
    15661 tggtaacagc gacggatgaa ggagaccctg ttcttgctat tggtggtcag gttaagcgtg
    15721 cagatctctt gaaacgtgcc caccaatcaa tgaataacgt tgctatgctt gagccaatta
    15781 ccaaatatgc tgctgaagta catgatgcta acaccctttc tgaaacggtt gctaatgcct
    15841 atcgtcacgc taagtcaggg aaaccaggtg caagcttcat ttcaattcct caagacgtga
    15901 cggatgctcc ggtcagtgtt aaggctatta agcctatgac agatccaaaa cttggttcag
    15961 catctgtttc tgatattaac tatctagcac aagccattaa aaatgcagtg ttgccagtct
    16021 ttcttttggg aaatggtgcc tcatcagaag ccgtaactta ctctattcgc caaattttga
    16081 agcatgttaa attgccagtt gttgaaactt tccaaggtgc cggtatcgtg tcacgtgacc
    16141 ttgaagaaga tactttcttt ggtcgtgtag gtcttttccg taaccaaccc ggagacatgt
    16201 tgcttaaaaa atccgactta gttattgcca ttggttatga cccaatcgaa tatgaagcac
    16261 gtaactggaa tgctgaaatt tcagcacgta tcatcgttat tgatgttgag ccggccgagg
    16321 tggacactta cttccaaccg gaacgtgaat tgattggtaa tgtagaagcg agcttaaact
    16381 tgcttttgcc cgctattcaa ggttataaat tgcctgaagg ttcggttgaa tatcttaaag
    16441 gtttgaaaaa caatgttgtt gaggatgtta agtttgaccg tcagcctgat gaaggtacgg
    16501 tgcatccgct agatttaatc gaagttttgc aagaacaaac agatgatgat atgactgtta
    16561 cggttgatgt tggtagtcac tatatttgga tggcacgtta tttcaaatcg tatgaaccac
    16621 gtcatttgct tttctcaaat gggatgcaaa cgctaggtgt tgctcttcca tgggctatct
    16681 ctgcagcttt ggttcgtcct aagacaaaag tgatttctgt ttctggtgat ggtggtttcc
    16741 tcttctcagc acaagaattg gaaacagcag ttcgtttgaa attgccaatt gtccatatta
    16801 tctggaacga tggtcattac aatatggtgg aattccagga agaaatgaag tacggtcgtt
    16861 catctggggt tgactttggt cctgtagatt ttgtaaaata tgctgagagc tttggagcca
    16921 aaggttatcg tgcaacaagt aaagcagcgt ttgctagctt gcttcaagag gctttgactc
    16981 aggctgtaga tggaccagtc cttattgatg ttccaattga ctataaagat aacattaaac
    17041 tcggcgaaac tattttgcca gatgaatttt actaaaaaga gggtgtagac atgtctgaag
    17101 ccataaaatt atttcaatat aatactttgg gagccttgat ggctgggctt tatggaggta
    17161 ctttaaccgt tggagagttg ttagagcatg gagacttggg tctcggaaca ttagattcta
    17221 tcgatggtga gttgattgtt cttgacggta aagcctatca agctaaaggc tctgaaggta
    17281 aagtcgaagt ggtagaagtt tctccagatg aaaaagttcc ctatgcagca gtcgtacctc
    17341 accaagctga agttatcttc cgtcaacgtt ttgaaatgac tgataaagaa cttgaggatc
    17401 gtattgaatc ttactatgat ggggttaatc tcttccgttc catcaagatt aaagggcatt
    17461 ttaagcacat gcatgtccgc atgataccta agtctactcc tgatacgaaa tttgctgaag
    17521 ttgcgactca tcaaccagag tatgaatctg ataatatttc aggtacaatc gttggtatct
    17581 ggacacctga aatgttccac ggtgtgagtg ttgctggtta ccatctccat tttatttcag
    17641 atgacttgac attcggtggt cacgttatgg attttgttat cgagaatggt attattgaag
    17701 ttggaccagt tgaccaactc gatcaacgct tcccagttca agaccgtcaa tatctctttg
    17761 ctaaattcaa tgttgatgaa atgcgtaaag atattactaa ggctgaataa gcatataaat
    17821 aagatactgt ctctttgtca actgtagtgg gtgacgaaaa gctaacatct agagaggacc
    17881 ggataggtcc tctttttatg tatgttcagt gtgatgaaga cacgtttctt aaagttgatg
    17941 aagtttctaa aaccgaagcc caagcgttta atgtctttaa ttaacttatt agtagcttcc
    18001 agttttgcgt ttgaatagtc tgtttctagt gcattttgga tgtattgctt gtgtctaaga
    18061 aaagtcctaa agaccgtttg aaaatagtga ttgaccttgc ttctattttc ctctatcagg
    18121 tcaaagaact cacctactct cttctcctga aagtgaaaaa gcaaaagctg ataaagtgta
    18181 tagtagtcag taagctcttt tgaaaagact agtgtcttct taacaacttc atgtggtgct
    18241 aaagtttggc ggaaagtctt tgaataaaaa gagttgagag ataacttaca gctgtccttt
    18301 tggaagagtc gccagtgatt tttcaaggct cgatagggta gtgacttttt atcgaattgg
    18361 ttcataattg caattcttgt ctttaaaaag gcacgtccaa ggtgctggat gatgtggaaa
    18421 cgatcaagaa cgatttttgc gtttggaaag agcttgcgag ccagtggaat ataagctcca
    18481 gaca
//
