LOCUS       c00007_JAHRBE0..       13578 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHRBE010000015.1 Streptococcus thermophilus strain FDL19 Contig_15,
            whole genome shotgun sequence.
ACCESSION   JAHRBE010000015
VERSION     JAHRBE010000015
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:54:07
            Original ID  :: JAHRBE010000015.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 206053
            Orig. end    :: 219631
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13578
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[216053:218213](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12160)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..13578
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13578
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             193..1461
                     /locus_tag="ctg7_226"
                     /transl_table=11
                     /translation="MPDNLALRMRPRSISEVIGQKHLVGEGKIIRRMVEANMLSSMILY
                     GPPGIGKTSIASAIAGTTKFAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHRLD
                     KAKQDFLLPLLENGNIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKEAILNVL
                     GDKERGFAFEVHLDDDALDFIATATNGDLRSAYNSLDLAVMSTPASGNGQHHITLDIVE
                     NSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLARRLTVI
                     AYEDIGLANPDAQVHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYKAMDAAL
                     ADLRKSGNLPIPRHLRDGHYAGSKALGNAQDYKYPHAYPEKWVKQQYLPDKLRGVNYFQ
                     PNETGKYERALGANKERIDKLSR"
     CDS             complement(1903..2727)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 80.9; E-value: 2.4e-24)"
                     /gene_kind="other"
                     /locus_tag="ctg7_227"
                     /transl_table=11
                     /translation="VWTRARDEPDVKSGEVLQAAVQTISSQAKAGYSNSQQKGTLIDDF
                     TQHVELFSSKEQQMTEEKYLHTEKDYLDLLLAVKRKFDYQRSIVPYIVYFLLKTGMRFG
                     ELVALTWNEVDFDRGLLKTYRRYNTLSHKFVPPKNKTSIRMVPIDEECIKILRLLQTEQ
                     ERANMELGIKNRYRMIFQHFGYIHSVPDIASVNKALSVLLNELDIYPIITTKGARHTYG
                     SYLWHKGFDLGVIAKILGHRDISMLVEVYGHTLEEKIFEEFNQIRDIWKDCS"
     CDS             2923..3435
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 59.3; E-value: 1e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg7_228"
                     /transl_table=11
                     /translation="MTFIIQNFGPNLARLRIEKGVSQTQLAEDLGIGKQSISDYEKQKS
                     YPTFANLDKIAEYFNATPTQLFGTSKEIELEKSVLESNEYSDKVSEILKAVKYIENFLE
                     TDGQYLEDLLYLTRGKQLYTEDGDELYTDPTSQKRTFHNQYEPGFIVARDKSPLELLIE
                     NKELFDK"
     CDS             complement(3839..5380)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 149.9; E-value:
                     1.8e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_229"
                     /transl_table=11
                     /translation="MLRSYVTKKHLTFYFLAIVITWLEAIITPALIQYIVASFTNRQLH
                     LLWQILLWGIGGNLVLVLGLAGKRYYYARLMTDFKVGIKRAIFRTFLYSRQIPDEEVLS
                     DLENDVQQLENSYIEPTVIIVSSLGFTVVSIAYALWTNFYLGLLFIIFYSVPVLCSGLG
                     SKRLDRIAEQKSLANQNYIARVNNMIAGIAPIRHYQGQNLFFKRFSKDLEQALQEEVSY
                     EKQRSLNSLFINSIDAFCSVAPIVIGGFMTYQNYLSAASFVGIYLVSHNIGYQFQELSY
                     FINTRKSAKSLCDKYQDLFGNKLATDSIFDQSVFPIQLEQVSVEKDGETILAPCDLTIH
                     AGEKIAIIGESGAGKTTLLNILYGEIHPSQGQIRYQGRELTSCQLYQAGAYILQSSHVF
                     DDLSVEENIALGQEIDQQRMDNILQETGLLSLKGKVPSNQTLSGGEKQRLEIARALYHK
                     RQFILADEVKANLDAKNQEKINQLLFSLPQAVVEVIHHYTKEDLKRYDKVIHLKK"
     CDS             complement(5373..6200)
                     /locus_tag="ctg7_230"
                     /transl_table=11
                     /translation="VKIETVTNGTVLNKRVKEMLVKFHPYLTISLDGPEIVHDRLRGRG
                     SHRKTLRFINYLKNIDYENFEIASTYTRLHQKNGLSREDIFQYFTDMDVHFNINDVFTK
                     NKVLIVKEMEKSLAERKQFIDKSIQHVINNNEKAFISPILYDVLISMIYKSTNRTFCDD
                     IDPSNTLTYDVDGSKKLCFRFWGTHNSPKAESFNNKDNFEKCKNCWCRGMCLECVANVI
                     DGYSSVISEDGEFLECSKPELMEYCIKQIIYLSKDREKLSRLVNNFRGFIRYA"
     CDS             complement(6190..6573)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_231"
                     /sec_met_domain="Fer4_12 (E-value: 6e-10, bitscore: 33.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTIETDIGTYYFDSVNFTLSLSPISKQSSPTLDSVEDGVLKKV
                     VINISNSCNLSCSYCYADGGNYGMDNRIMDLTTADNIIQEIASKGVTQINRLILFGGEP
                     FFKYRIIYIFYRKIIYIIKCSEN"
     CDS             complement(6630..6737)
                     /locus_tag="ctg7_232"
                     /transl_table=11
                     /translation="MEKLQVIDLEELLEFDQGYVINASCGPSHSCGGGR"
     CDS             complement(6815..7513)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_233"
                     /sec_met_domain="TIGR01716 (E-value: 2.1e-47, bitscore:
                     155.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIEEFVYAVRDFRRDDFNELLEKIRYLVSNRDIDGMKKLLISQM
                     EKKDKKEPFASFNTILIKIRLQDLSGETYVTDQEIVTISDYLFSAEYWGYYELLLFMNT
                     IDALNHNTMMILAKEMCHRLDFYRDIPNNRRLLATMSLNAYITCIERNEWMDALYFEKQ
                     LKYCNFSETEMYEKLVLHYANNLYDLKKNNNRHAVLEMRKCIAATKLVDSNQISIKFEN
                     YLQKVLDDMR"
     CDS             complement(8428..9996)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 125; E-value: 6e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_234"
                     /transl_table=11
                     /translation="MKKYILKYKLLNLIHIILIGFSSAFLVGASVTLSIMLNKLVESDF
                     KGFLIWLGIEFGVYLLFLADTYLIRVNQTKLIQKMTLSLRDDYINSLTRKSFSEFKNKT
                     VGEHLSILNNDIKIIEESGFESFYSLVSTVFTTFFSIIALFSYDYRIVLLSILLTLILT
                     YLPRSFAHKMEKAMKRFSIGNETFISSLTDQLLGYDTLYYSNKKEMLSIKCGEVIKKFI
                     FEKIVFIKTSSLIEIIMSLFSIISQMLVLLLTGYLIILKQVSIGSISSVGQISGNIFNS
                     LTTFNQLQVSISSVNIIFEKFGAFEKSSHYRYIDKDIEEIKLTNVGYSFKDKEIFKNIN
                     CSFEKGKNYAIVGESGSGKSTLINIILGNNKQYSGSVKYNDVEISDIEESQLFKSVSYI
                     GNITHIYHDSLRNNLTLWDNKINESEIINILKQVNLIDLIPRLDDEVSMSFLSEGQKQR
                     LGIARAYLTKTNVIIMDESMANLDRDNAFLIENQLLNDPTRMYITVSHHLQEKLLDRFH
                     SIITL"
     CDS             complement(10001..12160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_235"
                     /sec_met_domain="LANC_like (E-value: 1.2e-07, bitscore:
                     24.7, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 8.9e-14, bitscore: 45.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELITPSEKRIINRKKGEIYDYISYSNAFVPYQGWKIHISANLI
                     DYQSILDNVYHVCSIFQTPFKYINKISELFRILSKHVSQLEIGKFITIYPKNKETFLLL
                     LEELYDKIPKYTGVQILTDRSYKDSEIIFYRYGVMNARLINNERPKLKFNGTFYEDITE
                     PYYTCPPFVEDIIFNKVVDDYNIESLFHDRYQMESIIHKSGAGNVYIAIDTINEEKVII
                     KEARKKVYITEKILAIDLLLNEKCILKKLKGKVDIPNYIECFTIEGNLYLVEEFIDGQR
                     LDILKPEYNLLIKRNSSELGRYNKKVKKIISNLFLSLYKIHQEGIILEDISSSNILLTN
                     DDRVFFIDLETAYNKNDGIIVETTNECYPKNISQKNEQRDIVKMWYCIIDLLTNSTSLL
                     KYDNTGVSTLNLFYKMSLENNLPKSLRKKFINDFSIVDFKNTFIIKFIEMGLNIEKIVR
                     MQQDLTETILSHNTFEIYGKTILESIDNYKHISNMDLKFSSDPSFSSLYDNCNKSIDDL
                     IGIAILDNNFELFLNCNLDELLHNMSYYQKYYLLRLFNDTKICDRVYFIKVLNSIIKND
                     IKCIDGVKYIKSNEYFSPYLITGNSGLIIELIKFSKNNNTMKFDEWIRSLSEGISYTYA
                     KGTSLYYGLAGLGLANAWLYYYFKETSFLKTSIKICEHIFDFSIKQNTKTILIDPMSEE
                     IDYTYSKGMLGQLYFINELLNIIKE"
     CDS             complement(12245..13117)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_236"
                     /sec_met_domain="TIGR01716 (E-value: 1.5e-30, bitscore:
                     100.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTIDIGSLTKKIRLSKKLSLKDVAGDYLSVSFLSKFERGESEI
                     SLSRFLCILENLDVSIEEIYGILSKDNPTRTEELLARVSKAFQQNNIPALKKYYYEEIE
                     KFNSTHKKIFLYNSILIDSFLISITGKKMNKKHIEVISDYLFDVDQWGKRELVILGNSM
                     SAVPTNTLNLLIKEIIYKTTLFGNNEENKKIKIDLILNGISIFLERKELNYAKFYIDLF
                     DTLTIPEVYLYERVEYNILIGTYWILIGKIEVGKKKIELALESLKNLGAENLLLMRENE
                     YEELLNSII"
     CDS             complement(13278..13367)
                     /locus_tag="ctg7_237"
                     /transl_table=11
                     /translation="MTTQNLNKLPGTIAVPMDKIRITIYCPSF"
ORIGIN
        1 gtaaagtaac atactttagc catttcgtgt tttcctccta ggtagaattt attacggatg
       61 tgctagcacc acataccaaa atattctatc ataagaattt aggtttgaca agaactattt
      121 ataatttctt tttacagaaa aatagtatat tcttattata agaagaataa atagttaaaa
      181 aaaggagaga agatgccaga taatcttgcc ttacgcatgc gtccacgttc aatttcagag
      241 gtgattggtc agaaacattt agttggtgaa ggtaaaatta ttcgccgtat ggtagaggcg
      301 aatatgctgt cgtcaatgat tctctacgga cctccaggaa tcgggaaaac ctcgatagcc
      361 agtgctattg caggaacaac aaaatttgct tttagaactt ttaatgccac tgtcgatagc
      421 aaaaaacgtc tacaggaaat tgcagaagag gctaaatttt caggtggttt agttctactt
      481 ctagatgaga tccatcgttt ggataaagcg aaacaagatt ttttgttacc attattagag
      541 aacggaaata ttatcatgat tggtgccaca accgagaatc cgtttttttc tgtaacacca
      601 gccatccgta gccgtgtaca aatatttgag ttggaaccac tctctaatga agatatcaag
      661 gaagctattt tgaatgttct aggggacaag gagcgtggct tcgcctttga ggttcactta
      721 gatgatgatg ctctagattt tattgcgaca gctactaatg gtgatttacg atcggcatat
      781 aattctttgg atctggctgt catgtcgaca ccagcttcag gaaatggtca gcatcatatt
      841 accctagaca tagtggaaaa tagcttacaa cgcagttata ttactatgga taaagacggt
      901 gatgggcact atgatgtcct ttctgccttg caaaaatcta ttcgaggatc tgatgttaat
      961 gccagtcttc actatgcggc acgtttggtt gaggcagggg atttgcctag tctagcacgt
     1021 cgcttgactg tgattgccta tgaggatatt ggtttagcta atccagatgc acaagttcac
     1081 acggtcacag ccttggaagc tgcacagaaa ataggttttc cggaggcacg tattttgatt
     1141 gccaacgtag ttattgactt agcattatca cctaagtcga attcggctta taaggcaatg
     1201 gatgctgccc tggcggatct tagaaagtct gggaatttac ctattccgcg tcatctgaga
     1261 gatggacact atgctggaag taaggcactg ggtaatgcac aagattataa gtatccacat
     1321 gcctatcctg aaaagtgggt taagcaacaa taccttccag ataaattaag aggagtcaat
     1381 tatttccaac ctaatgaaac tgggaaatac gaaagagctc ttggagctaa taaagaacga
     1441 atcgataagt tatctagata atacgagaag aatcaacgaa aacgattgca aaaaaaatga
     1501 tttttcctct tgcaataatt ttcaaaagtg gtattataaa aacatagaaa ttgctgtggt
     1561 atacgaatcc acatataagt gttgaccgac taatttttgt attatcggga gacagaggtc
     1621 tattaacagt gtgcaggctg gctcacccag aagcaactga agttagtagc gagtcgccca
     1681 cctgcttttt tacgtcgcgg gttcaataca aactgtggat catcggtacc aatacagcat
     1741 ccagcctcct tagctcagtt ggtagagcag tggactctta atccatgggt cacaggttcg
     1801 agccctgtag ggggcatcaa acttcaacag taaaagcctt gataaccaag gcttttttgc
     1861 ttgtcttaag agcatttgcc ccatcgtttg ccccacattt ttttatgagc aatctttcca
     1921 gatatctctg atttgattaa attcctcaaa aattttctct tctaaagtgt gtccatatac
     1981 ttctaccaac attgaaatat ctctatgccc tagaattttt gcaataactc caaggtcaaa
     2041 ccctttgtgc cagaggtagc ttccataggt gtgacgtgct ccttttgtcg tgataattgg
     2101 ataaatgtcc aactcattta agagaacact caaagcttta ttgacgcttg caatatctgg
     2161 aactgaatga atatatccaa aatgttgaaa gatcattcga tatcgatttt tgattcctaa
     2221 ctccatgttt gctctttctt gctccgtttg taaaaggcgc aaaattttga tacactcttc
     2281 gtctattgga accatccgaa tagacgtttt attttttggt ggaacaaact tatgagagag
     2341 agtattatac ctcctgtatg tttttaacaa tcctctgtca aaatcaacct cattccaagt
     2401 taacgctact aactctccaa acctcatgcc tgtttttaat agaaaataga cgatataagg
     2461 aacaattgaa cgttggtaat cgaattttct ctttactgct aaaagtaaat ccagatagtc
     2521 cttttctgta tgtaaatatt tctcttctgt catctgttgt tctttggatg aaaacaactc
     2581 gacatgttgt gtaaaatcat ctattagtgt acctttttgc tggctgttag aatagccagc
     2641 ttttgcttgg ctagaaattg tctggacggc agcctgcagg acttcgcctg acttcacgtc
     2701 aggctcgtcc cttgctcttg tccacacaat ttctagctcc aaggcttcga atagtcatca
     2761 gtcatagtca tagtctcatc ctcaaattcc tcctcactca ctattcctaa acatatgagc
     2821 tatttgtatc atttaaaaaa tattttgagc agtcaactaa aaacttgatt tgtaagttta
     2881 taggtgatag aataagttta aaatacaaca taggagttta tcatgacctt tattattcag
     2941 aattttggac ccaatttggc acgactacgc atagaaaaag gagtaagtca aactcaactt
     3001 gcggaagatt taggaatcgg taaacaatcc atctctgact acgaaaaaca aaaaagctat
     3061 cctacctttg caaatttgga taagatagca gaatatttta atgcaactcc aacccaacta
     3121 tttggaacta gtaaagagat tgaattagaa aagagtgttc ttgaatcgaa tgaatactct
     3181 gataaagtaa gtgagatctt aaaggctgtc aaatacatcg aaaattttct agaaactgat
     3241 ggacagtact tagaggattt actttaccta acaagaggca aacaactata cacagaagat
     3301 ggagacgagt tgtatactga tccaacttct cagaaaagaa catttcataa ccaatatgaa
     3361 cctggtttta ttgtagcaag agacaaatct ccactagaac tcttgattga aaataaggaa
     3421 ttatttgata aatagaaaaa gcgagtttga actcgctttt tctgttatga aagaaataac
     3481 ttattttcta gttttttaga taaatcctct ctccaaatat ccgtcacggt cgcttcttac
     3541 cagttctttg ggcttacgca agattttaat caattttgag ttaaaaataa atactctaaa
     3601 tactcattca attcattaat tatttagtca atggttgctt tgtatccaca attccaaata
     3661 gttctaaatg agattttagg aactttgaaa actttaaaaa acgcattctt atcactttga
     3721 agataagaaa agagagaacg aattgtgtcc tctctcgatg ttagcttttc atcaactcaa
     3781 gacagttgac aaagagcctt tcagatatac aatttgtcta tagacactat tggcataact
     3841 actttttcaa atgaatcact ttatcatagc gcttcaagtc ttccttggtg tagtggtgaa
     3901 tgacctccac cacagcttga ggaagtgaaa agagcagctg gttgattttt tcttgatttt
     3961 tggcgtccag gttagccttg acctcatctg ctaggataaa ctgtcgcttg tgatagagag
     4021 cacgggcgat ttcaaggcgc tgtttttcac cgcctgataa agtttggttg ctgggtacct
     4081 tgccttttag gctgaggagc cctgtttctt gcaagatgtt atccattctt tgctggtcaa
     4141 tttcctgtcc cagagcgatg ttttcctcca cagataaatc gtcaaaaaca tgactagatt
     4201 gcaagatata ggcaccagcc tgatagagtt gacagctggt tagttcccgt ccttgataac
     4261 gaatttgccc ctgactagga tggatttccc cgtataggat gttgagcagg gtggttttgc
     4321 ccgctccgct ttctccgatg atagcaatct tttccccagc gtggatagtc agatcacaag
     4381 gagctagaat ggtctcccca tccttctcca cactgacctg ctccaactgg ataggaaaga
     4441 cagattggtc aaatatgctg tcagtagcca acttatttcc aaacaagtct tgatacttat
     4501 cgcagaggga cttggcagac ttgcgggtat tgataaagta ggacagttct tgaaactggt
     4561 agccgatgtt gtgggagacc agataaatgc cgacaaaact agccgcagaa aggtagttct
     4621 ggtaggtcat gaatccgcca atcacaatgg gcgccacaga gcaaaatgca tctatactgt
     4681 tgataaataa actgtttagt gaccgttgct tttcgtagga cacttcttct tgcaacgcct
     4741 gttctaggtc tttagaaaat ctcttgaaaa acaaattctg gccctgataa tgacgaatag
     4801 gagcaatacc tgcaatcata ttgttgacac gggcgatata attctgattt gccagggatt
     4861 tttgctccgc aatcctatcc aaacgcttcg aacccagtcc gctacacaaa actggtaccg
     4921 agtaaaagat gataaacaat aaccccagat agaaattggt ccagagggca tatgcgatgg
     4981 aaacgactgt aaaacctagc gaggatacga taatgacggt cggttctata tagctatttt
     5041 ccaactgttg gacatcattt tccagatcag acagcacctc ctcatcagga atctgacggc
     5101 tgtataaaaa agtccgaaaa atagcgcgtt ttatcccaac cttaaagtca gtcatcaaac
     5161 gagcatagta atagcgcttc ccagccaagc ccaggacaag caccagattg cccccaatcc
     5221 cccagagcaa aatctgccag aggagatgca actggcggtt ggtaaaacta gcgacgatat
     5281 actggataag ggcaggggtg ataatggcct ctaaccaagt gatgacgatg gctagaaaat
     5341 agaaggtgag atgttttttc gttacataac tcctaagcat agcgtataaa ccccctaaaa
     5401 ttatttacca acctagataa tttttctctg tccttggata aatatataat ctgtttaata
     5461 cagtattcca tcagttctgg tttagagcat tcaagaaatt ccccatcttc actaattaca
     5521 gaagaatatc catcaataac attggcaaca cattccaagc acatacctct acaccagcag
     5581 tttttacact tttcaaagtt atctttgttg ttaaatgatt ccgctttagg actgttgtga
     5641 gttccccaaa atctgaaaca tagtttctta ctaccatcta catcataagt taatgtattc
     5701 gaagggtcaa tatcatcaca aaatgtacga ttcgtactct tgtatatcat tgatattaat
     5761 acatcatata aaataggact gataaatgcc ttctcattgt tgttgattac atgttgaatg
     5821 gatttatcta tgaactgttt tctttcagcc aaactttttt ccatctcttt cacaattagc
     5881 actttatttt tagtaaaaac atcatttata ttaaaatgca catccatatc agtaaaatat
     5941 tgaaagatat cttctctact tagaccattt ttttgatgaa gtctagtata tgtcgaggct
     6001 atttcaaaat tttcataatc aatattcttt aaataattaa taaaacgtaa tgtttttcga
     6061 tggctccctc ttcctctgag tctatcatga acaatttctg gtccatctaa acttatggtt
     6121 aaataaggat gaaatttaac aagcatttct ttaacacgct tatttaaaac agtaccatta
     6181 gtaactgttt caattttcac tacatttaat aatgtagata atttttctat aaaatatata
     6241 aataattcta tatttaaaaa aaggttctcc cccgaaaagt atgagacggt tgatttgtgt
     6301 aactccttta cttgctatct cttggataat attatcagca gtagttaaat ccataatacg
     6361 attatccata ccatagttac caccatctgc ataacaatac gaacaagata aattacaact
     6421 attagaaata tttataacta ctttttttaa tacaccatct tcaacagaat ctagagttgg
     6481 tgaactttgt tttgaaatag gtgacaaaga taaagtaaaa ttaacagaat caaaataata
     6541 tgttcctata tctgtttcta ttgtctttat cataattatc ctccagacta aaaactgaga
     6601 tgaggaatca ctcctcatct cggaagaagc tatcgaccac cgccacaaga atgacttgga
     6661 ccacagctag cattaattac atacccttga tcaaactcta aaagttcttc aaggtcaatc
     6721 acctgaagtt tttccatggt tttcacctcc tttatttgat agtttcatta tataacctta
     6781 tcagaagagg ataatatttt cccttatacg caattcacct catgtcatct aatacttttt
     6841 gtaaataatt ttcaaatttt atagatattt gattgctatc taccaatttc gtggcagcaa
     6901 tacattttct catttccaaa acagcatgtc gattattatt tttctttaga tcatataaat
     6961 tattagcata atggagcact agtttttcat acatttcagt ctctgaaaag ttacaatatt
     7021 ttagctgttt ttcaaaataa agagcgtcca tccattcatt gcgttcaata caggtgatat
     7081 aagcattgag cgacatagtt gccaataaac gtctattatt tggaatatct ctataaaaat
     7141 ccaaacgatg acacatttct ttggctaaaa tcatcattgt gttatgattt aaagcgtcta
     7201 ttgtattcat aaacagtagc aattcataat aaccccagta ttccgcagaa aacaagtaat
     7261 cactgatagt aacaatctct tggtctgtta cataagtttc tcctgataaa tcctgtaatc
     7321 ttattttaat caaaattgtg ttaaatgaag cgaaaggttc ctttttatcc ttcttttcca
     7381 tttggctaat taatagcttt ttcattccgt ctatatcacg atttgatact aaataccgaa
     7441 tcttttctaa aagttcatta aagtcatctc tgcggaaatc acgtacagcg taaacaaatt
     7501 cttcgatagg catatgtatt gcatctaacg ctaaaaaaat tgctgatggt taaatcagcc
     7561 tcatcatttt caaatcttga gagatgggaa cttgaaagac ctgattttgc aacatttttt
     7621 aaagataaac ctcgagattc tctaaatttt ttaaaaattt ttccatattt cattctagtc
     7681 acctcctaaa ttgcttataa gggaaatttc ttcacaaata ttaaaaatat tatatcatat
     7741 aagaaaacga aaagaggtat ttaccatgaa taaaaaagca ttgtttagtt tgttgtttgt
     7801 aatacttgaa ggtattatcg ttatcggagt aggttagcca aatgataaag agattaggca
     7861 agaaacctta aaaataaaaa atagcttaga attgcgtcat tataaacgtt gattccaagc
     7921 tatttttggt tattaaaatt ttaatcagaa gggtaaactt gtagtttttg cccaacctct
     7981 cttgatttta tggaaaaaga atcccgtatt ttggatacga aatgctttca ataagtgtaa
     8041 atcagtttta acgtttacta aatttcgatg ctttacgagc ctttttcaag cctggttttc
     8101 aaagcaagtt ggaaaccttt atgagtcatt cgtttttgcc ccacttttgc cccattttga
     8161 aataattata tttaaaaatg ctccaagtat cttctaaaaa taacttatat ttcaacattt
     8221 ttgattattt tcaatatgaa aaattcatac aaattcatgt agggggcatc atactataca
     8281 taaaaaagcc tttaaataaa ggctttctta cttgtctaaa gaggaaatgt cccatcattt
     8341 gtccccgaaa taatttccaa acttttgata aatattattt ttgtataaat taatttttgt
     8401 tgtgtatagt aacattgaat tctcaattta aagtgtaata atactatgaa atctatctag
     8461 tagtttttcc tgtaagtgat gagagacagt aatgtacatc cttgtaggat cgtttaatag
     8521 ctggttctca attagaaaag cgttatctct atctaaattt gccatagatt catccattat
     8581 tattacgtta gttttagtaa gataggcacg tgcaatacct aatctttgct tttgcccttc
     8641 tgataaaaaa gacatactta cttcatcatc taatcgtgga attaaatcta ttaaattaac
     8701 ttgtttaagg atattgataa tttctgattc atttatttta ttatcccaaa gtgttaaatt
     8761 atttctaaga gaatcatgat aaatatgagt aatatttcct atatatgaaa cgcttttaaa
     8821 caattgagat tcttcaatat cagatatctc tacatcattg tattttacac ttccactata
     8881 ttgcttatta tttcctaaaa ttatatttat taaagttgat tttccactac ctgactctcc
     8941 aactatggca taattttttc ctttttcaaa actacaattt atatttttga aaatttcctt
     9001 atctttgaag gaatacccga cattagttaa cttgatttct tcaatatctt tatcaatata
     9061 tctataatgg gaactcttct caaaagctcc aaatttttca aatataatat ttactgatga
     9121 tattgatacc tgtaattgat taaacgtagt taatgagtta aatatatttc cggaaatttg
     9181 tccgactgat gatattgaac caattgaaac ttgttttaaa atgataagat aacctgttaa
     9241 aagtagtact aacatttgag aaataattga aaataaactc attattattt caattaagct
     9301 actagtttta ataaatacta ttttttcaaa aataaatttt tttattacct ctccacattt
     9361 aattgataac atctcttttt tatttgaata atatagcgta tcatatccca gtaattgatc
     9421 tgttagtgat gaaataaatg tttcattacc tatagaaaat cttttcatag ctttttccat
     9481 cttatgggca aaacttcgtg gaaggtaagt taggatcaaa gtaagtagta tagataaaag
     9541 cactattcta taatcataac taaacagagc aataattgaa aaaaaagttg tgaaaactgt
     9601 tgaaactaat gaataaaaac tttcaaatcc gctttcttcg ataattttta tatcgttatt
     9661 taaaattgac aagtgttctc caacagtctt atttttaaat tcactaaacg attttctagt
     9721 tagactgtta atataatcat ctctgagaga aagagtcatt ttttgaatta atttagtctg
     9781 atttactcta attaagtatg tatctgccaa aaataacaaa taaactccaa attcaatgcc
     9841 taaccatatg aggaagcctt taaaatcact ttcaaccaat ttatttaaca tgattgagag
     9901 tgtgactgat gctccaacta aaaatgcaga actaaatcct attaatatta tatgtataag
     9961 atttagcagt ttatatttta gtatatattt tttcattatg ttattcctta attatattta
    10021 gcaactcatt aataaagtac aactgcccca acattccttt tgaatatgta taatcaattt
    10081 cttcggacat cgggtctatc aatatagttt ttgtattttg tttaatagaa aaatcaaaaa
    10141 tatgttcgca aatcttaata ctcgttttaa gaaatgaagt ttctttaaaa taataataaa
    10201 gccaagcatt tgccaaaccc aatcctgcta atccataata caatgaggtt cccttagcat
    10261 atgtataact aattccttct gataaacttc taatccattc atcgaacttc attgtattgt
    10321 tatttttact gaacttaata agttcaatga ttaacccaga gttaccagtt attaaatatg
    10381 ggctaaaata ctcattggat tttatatatt tcactccatc aatacactta atatcatttt
    10441 tgatgattga atttaggacc tttataaagt agactctatc acatatttta gtgtcattga
    10501 aaagtctgag tagataatat ttttgatagt agctcatatt atgtagtagt tcatctaaat
    10561 tacaatttaa aaaaagttca aaattattat caagtatagc gattccgatt aagtcatcta
    10621 tacttttatt acaattatca taaagagaag agaaactggg atcgctagaa aattttaaat
    10681 ccatattact aatatgttta taattatcaa ttgactctaa tattgttttt ccataaattt
    10741 caaaagtatt atgggaaagt atagtttctg ttaaatcttg ttgcattcta actatttttt
    10801 ctatatttaa acccatttca ataaatttta ttataaatgt attcttaaag tccactatac
    10861 taaaatcatt aataaatttt tttcttaaag atttaggtaa attattctct aaactcattt
    10921 tataaaataa atttaaggta ctcactcctg tattatcata ttttaaaaga ctagtagaat
    10981 tagttaataa atcaattata caataccaca ttttaacaat atctcgctgt tcattttttt
    11041 gagaaatgtt tttgggatag cattcatttg tcgtctcaac aataattcca tcattcttat
    11101 tatatgcggt ttcgagatca ataaaaaata ctctatcatc atttgttaaa agaatattac
    11161 ttgaagatat atcctctaat attattccct cctgatggat tttatataaa cttaaaaata
    11221 gattagaaat tatttttttt acttttttat tatatcttcc taactcgcta gaatttcgtt
    11281 ttatcaacaa attatattca ggctttaaaa tatccaatct ttgtccatca atgaattcct
    11341 caacaagata taaatttccc tcaattgtaa agcactcaat gtaatttgga atatcgactt
    11401 tacctttcaa tttttttaga atacattttt catttaaaag gagatctatt gctaaaatct
    11461 tttctgtaat atatactttt tttctagctt cttttataat aaccttttct tcattaatag
    11521 tatcaatcgc aatatataca ttacctgctc ctgatttatg aataatagat tccatttgat
    11581 atctatcatg gaataaagat tcaatattat agtcatctac aactttatta aatatgatat
    11641 cttcaacaaa tgggggacat gtatagtatg gttccgttat atcttcataa aaggttccat
    11701 taaatttaag ttttggtcgc tcattattaa ttaaacgtgc attcattact ccatatctat
    11761 aaaaaattat ttctgagtct ttataacttc tatctgtcaa aatttgaact ccagtatatt
    11821 tgggtatctt atcatatagt tcttccaata ataataaaaa agtttctttg tttttaggat
    11881 atatagttat aaattttcca atctctaatt gcgaaacgtg ttttgataaa atacggaata
    11941 actcagatat tttattgata tacttaaatg gcgtttgaaa aatagaacaa acatggtaaa
    12001 cattatctaa aatagactga taatctatta aattagcaga tatatgaatt ttccaacctt
    12061 gataaggaac aaaagcattt gaatatgaaa tataatcata tatttcccct ttttttctat
    12121 taatgattct cttttcactt ggtgtaatta gttcttccat gataaatctc ctattaaaaa
    12181 taaaatactg ctgtataact atataactag tgtaacagca gtattttatt tttagtaaaa
    12241 agtgtcatat aatagaattc aataattctt catattcatt ttctctcatt agcagtaaat
    12301 tctcagcacc taaatttttg agggattcca aagctagttc aattttcttc ttgccgactt
    12361 ctattttacc tataagtatc caatatgtac ctattaatat attatattcc actcgctcat
    12421 agagataaac ttcaggaatg gtaagtgtat caaaaagatc aatatagaac ttggcataat
    12481 ttagttcttt cctctctaaa aatattgaga ttccgtttaa aataagatca atttttattt
    12541 ttttattttc ctcattatta ccaaataaag tagtcttata aataatttct tttattaata
    12601 aatttaatgt atttgtaggc accgctgaca tactattacc taatattact aactctcttt
    12661 tcccccattg atctacatcg aaaagataat cagaaataac ttcaatatgt tttttattca
    12721 tttttttacc tgttatcgat attaaaaatg aatcaatcaa aatagaatta tataaaaata
    12781 tttttttgtg tgttgaatta aacttttcta tttcttcata ataatatttt tttagagcag
    12841 gtatgttatt ttgttgaaat gccttactga cccttgctag taattcctca gttcttgtag
    12901 gattatcttt cgataaaatt ccgtaaattt cttcgatact tacatccaaa ttttccaata
    12961 tacaaagaaa acgagaaagt gaaatctcag actcgccacg ttcaaactta gataaaaacg
    13021 aaaccgaaag ataatcacca gcaacatctt ttaatgaaag tttttttgat aatctaattt
    13081 ttttcgttaa agaacctatg tcaatagtat caatcataaa ataactcctt ttatacaatt
    13141 ataacaaaaa acgcaaacat agtgcagtct gcgttaacct tttgaatatt aggagtatat
    13201 tgtaatacga agtctatctt taaattcaaa agaatcactt ggtaaactgt tcaaaatttg
    13261 aataatcatt tttctcctta aaaacttgga cagtaaatcg taatacgaat tttatccatt
    13321 ggaactgcaa ttgttcctgg taacttattt aggttttgag tagtcatttt tttctccttt
    13381 ctaaatctta tagacatatt atatattttt gcaataatta agtattaata ttttcatata
    13441 taggaattgc ccgatactgt caataattat gtgtaaacac tcaagtagag ttgaagaatg
    13501 ttaatcaaat aagctttcaa gtgtgtcagc acattggcca aaccctttat ggatgcgttg
    13561 attttgcttg aaattata
//
