LOCUS       c00015_JAHRBF0..       12859 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHRBF010000022.1 Streptococcus thermophilus strain FDL17 Contig_22,
            whole genome shotgun sequence.
ACCESSION   JAHRBF010000022
VERSION     JAHRBF010000022
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:58:41
            Original ID  :: JAHRBF010000022.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1646
            Orig. end    :: 14505
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..912)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 99; E-value: 4.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg15_1"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNS"
     protocluster    1..12859
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[4658:7083]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3013..5437
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..12859
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12859
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(1142..1231)
                     /locus_tag="ctg15_2"
                     /transl_table=11
                     /translation="MKEHFVIRGKRDFIVNKVADEYIGYDLLD"
     CDS             complement(1228..1665)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_3"
                     /sec_met_domain="TIGR04085 (E-value: 3e-15, bitscore: 51.0,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.1e-12, bitscore: 42.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVMFFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAG
                     VRACSINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLRSITFDDISGKC
                     SECPLPWCGGGCRCSALELDGTLLGSDLACFYEQKGGGVVV"
     CDS             complement(1616..1831)
                     /locus_tag="ctg15_4"
                     /transl_table=11
                     /translation="MLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERISKGE
                     FKVKFKIVPPNESDVFFDTLFSACIL"
     CDS             complement(1925..3016)
                     /locus_tag="ctg15_5"
                     /transl_table=11
                     /translation="MSKKIFNLYGMNMFLSGLPYYFVGILLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSYISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESL
                     SSGVLISYNFEIIDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVF
                     VIFSLLYLIGLPEIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLL
                     MRVLNSNYNNHFYYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNY
                     LIFGIVALCCLVSYSFSNREKRT"
     CDS             complement(3013..4332)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_6"
                     /sec_met_domain="PF04055 (E-value: 2e-18, bitscore: 62.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.8e-13, bitscore:
                     43.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 6.3e-24, bitscore:
                     79.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEIATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQNARKHVAKLKKHNILS
                     FPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGKPT
                     RYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDPKLNFEL
                     MGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEV
                     TGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEF
                     GEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSF
                     RTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             complement(4402..4494)
                     /locus_tag="ctg15_7"
                     /transl_table=11
                     /translation="MSKELEKVLESSSMAKGDGWKVMAKGDGWE"
     CDS             complement(4577..5437)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_8"
                     /sec_met_domain="TIGR01716 (E-value: 3.1e-50, bitscore:
                     165.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGEIFKKFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMELED
                     RREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYYELLIFSNTLDVL
                     NHDVFMVLAREMFRRSDFYKEIPNNRRLISTMLLNGYITCVEREKFMDALYFEKQLNQC
                     FFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSHHLAKTYEGHLEK
                     ILASS"
     CDS             complement(5677..6489)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 266.8; E-value: 2.9e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg15_9"
                     /transl_table=11
                     /translation="MLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIFTEHKGNYG
                     YRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAENLIQRQFE
                     ASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQVKAMLEQAF
                     TEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESFFGILKSEM
                     FYGYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             complement(6507..7073)
                     /locus_tag="ctg15_10"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYTIVEKTRGRLSKMGRKPKKKLEEMERLQAENEYLRAENAV
                     LKKLRELRLREEKEQEEKRKLSEDW"
     CDS             complement(7252..7410)
                     /locus_tag="ctg15_11"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             complement(7563..8075)
                     /locus_tag="ctg15_12"
                     /transl_table=11
                     /translation="LAAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQ
                     PYMTESAYSQELTSQNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSD
                     LKNANQSKTNQTETRTVNLNYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPS
                     LPNTTTK"
     CDS             complement(8475..11654)
                     /gene_functions="other (smcogs) SMCOG1218:Exonuclease
                     (Score: 492.8; E-value: 3.7e-149)"
                     /gene_kind="other"
                     /locus_tag="ctg15_13"
                     /transl_table=11
                     /translation="MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFD
                     AMTVALFATTSGDRNVEEMRSTFAGPEDDLTKVTFYFQQGNHLYRIDRVLQQERAKQGG
                     GTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFS
                     RFLKEDSKTKTQILKKIFGTGIFDHFQKSLEERLRQSNKDMEKRQAQLDGHFASQVWSE
                     EELSVLEQTPASEKLTRLEEFLSQRQENVTKQKSILKAAHEDLAQLQKSLQTAQDLAKI
                     FQEVEQAKERYRLEIEEGAQGQAEAKVHLEELQFAQGLQETIRTLKQYRKQLMQLEQDL
                     DIAQEVLSEKRQAFEDVKAQKEELAVQSKDFLQKEEELETWKEDIIYAQSLAQEQEKIK
                     RSMTNYKQLEETYQQARKEIEMLNKSLSDLEANRLSLESLHEAEKLFQIVGYSVENQLA
                     QDLKEIENLNQELTKTEKRHQTLSFDIDQAQEILKELEEELRRTLVSRRQLIIVQLQAE
                     LEEGHPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQATLSEV
                     ASKRQDLLDQVAKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQYYQE
                     LQKRYDKEETDYIRYQDELGKAQKKATDLAKTYQEAKAVLDQAQERLEDLQEAHPELES
                     VEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDVKR
                     LSAELEQSLKAEGALANDLEQVELWLIEVNNQAIPMLQAKLTTYATLKQELQAQIHKGQ
                     ELLQNQEQPDLDSLAQAVQNCQEIYDRQLAQFSVMEKGLKDATATYQAAKTLQDSNQEA
                     FKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLTDNRYSFV
                     LSEKGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGA
                     VVEALFIDEGFGSLDKEALTKAISVLEQIGENRMVGVISHVDDMKEGIAQQLVIIKSHD
                     GSSRIKIVDKG"
     CDS             complement(11651..12859)
                     /gene_functions="other (smcogs) SMCOG1230:Nuclease SbcCD, D
                     subunit (Score: 253.5; E-value: 8.1e-77)"
                     /gene_kind="other"
                     /locus_tag="ctg15_14"
                     /transl_table=11
                     /translation="MKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEKVDGVII
                     SGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFFQHQGLH
                     LSTRLEEAFEPIELENCQIFLLPFIDPIDARIYYKDDEGKEIQGIGDALTYILEDMEKA
                     FDPDKAHVLVTHFAVSKKDDSDGQGLRELMLSETSNTVGGLTNVTSDLFKSFDYVALGH
                     IHTRFASPTKRVQYSGSPVAFNVKEAKRKEEKGVYILELDASGDMSQTFHTLEVKRPIV
                     ALQESFETLMSPEFYKNQPCQKAWFAFDIQLSSRKELEGINVRARLEEIYGTDIVEITF
                     SRLGDVREENLTVDQHLKDLEMQSPQEIVFDFYQTVTGGDVLSERQTALVESVFEEIER
                     SRQ"
ORIGIN
        1 ttatgaattt ttaaatatgt tttttaaaaa tacgttaacc tctcctattt tctctgcttc
       61 aggtaaatag atagaaacgg ttgtcgaata aacaaaagaa ggtacactca caattgaaag
      121 caattgacta ataactgcat aaatagccaa caattctact cctaatctcg acatcaaggc
      181 atcaaacacc ataataaaca aaacactctc cagaatttct tgaccaacca aaggaatacc
      241 aaatgttatt aattcaaatt tagttgtaga tgtaatggat aaagccttca aaatcattgg
      301 ataaaccata aacaagtaac taagcgatat gaaagctaag gatacaatcg ttgatatggc
      361 tgctccctta attccgattt gtggtaccag tacataattt aacacaacat ctattaatga
      421 actgataagt ccaacccaca taattggttt tgttttcttt tgaactctta ataaatttgt
      481 cagcgaaaag tttaataatg tcaatccgat atatggagac atgaagacta aataaatggt
      541 ggataaggac aatagttgcc ctttaaatcc atagagctgc ttcaagatta catttccaaa
      601 aataatgaca aaaaccgcaa aggcaactcc gataattaaa tctaaggtta gatttgattt
      661 caataaatca tcaaacctgt tagtttgccg attagagtac gccttagagc ttttaatatt
      721 aaatgacaaa ctgaatgctc ctaaaagtcc accaaaagca aataagagat tctgaataat
      781 ggaaattcct gacagagcaa ttgaggaatt gttcacagca aaatgcaatg ctatctgccc
      841 aataattact tgaccaatat ttgttaaaac taagggaaag gcaaatttgt taatttcttt
      901 tgaatctatc atttttcctc tctaaaaggc ttcaaatgta agtaaagatc agatttaact
      961 aaatttgcat aaataatatg caaaatagga gtttcttcta aaaatgaaat aattgcctgc
     1021 ttacaatcat tagcagatac ctcataatct tgctgtaata gttctacaat cttgtctaaa
     1081 gaaaaatttt tagaaatgca ataaagtatt tctgctccta tttcatcaaa tgaatagtac
     1141 tctaatcaag tagatcgtat cctatgtatt catctgctac tttatttaca atgaaatctc
     1201 tcttacctct tatcacaaaa tgttctttca tacgactact ccacctcctt tttgttcata
     1261 aaagcaggct aaatcagagc ccagtaacgt tccatctaat tccaaggcac tgcatcgaca
     1321 tcccccacca caccatggta ggggacattc tgaacatttc ccagaaatat catcaaatgt
     1381 aattgatctt agtttattaa atacagcaga atggtgccaa atttcgctaa acttttgttc
     1441 tttaacattt ccagcaacta attcatctat accattcatc aagtcacacc cgtatacatc
     1501 tcctttatga ttaattgaac atgctctaac tccagcttga caagatattt cccttggctt
     1561 atcaaaattt atatctactt tttgatgcca aacattttct aataaatctg atctattata
     1621 aaatgcaagc ggaaaataat gtgtcaaaaa aaacatcact ttcattagga ggaacaattt
     1681 taaatttaac tttgaactct cctttagaaa tccgctctgt taaatcaaga aaaacaggat
     1741 accattgttt tttatctgct aaaatactac cgtcattagc cctaccagta ggacaaataa
     1801 ccataactga catatactca ataccaagca tatcattcaa tcttatactc taaagaaaat
     1861 atctgctaaa tttgcaaaca attgtgctat caataatttg gcaaatgaat tagaaataca
     1921 acttttaagt tcttttctct ctgttagaaa atgaataaga tactaagcaa caaagagcta
     1981 ctataccaaa tattaaataa ttgctcctaa tactaaagtt atcagcaaaa ataccagcta
     2041 ggaaatcagc taacataaaa ctaatcgaaa taaacaaatt atatactgac catgatactg
     2101 ctctattttt ttctattgac atattaaatt tataataaaa atgattattg tagttggaat
     2161 taagaacacg cattaataaa aggattataa tttggatgat tagattagtt tgaaaaaaca
     2221 tgagtatagc taatactggt aacatcaagc ttacttcaaa cttaattttt agataactcc
     2281 ccaaagccat agatatatta aacataaata gtataattcc cagcatatct agtgaaagtc
     2341 cctgttcatt taagaatatc cctgcataag aattgctaat cataattaga gttgagaatg
     2401 ctactcctaa tattattaat aaccatggaa tattttgaat attatcgagg ctaaaaaatt
     2461 tttgtttatt attttgttcc tttttaatct cgggtaatcc tattaaatat aataaactga
     2521 aaattacaaa tacaatggat ataataatag gataaatata attcctatgc aataaaggtg
     2581 gagatataat cgtaataata gcaataaaaa tatattttaa tgtgttgaga tttttcaaaa
     2641 atgatttata tacaacttcg tcatcaatta tttcaaaatt ataagaaata agaactcctg
     2701 aagataatga ttctgacaat ccaaaaaata tcgctgaaat atatattata tttgattttc
     2761 caaacaatag gccccataat gctaaaatta ataataaatt tgaaatagcc aaaattttct
     2821 tgtaaccaat cttacttgaa atataactta aaggaatatc aaaaactgag ccacatagct
     2881 cagtaataac tgataaagta gctatttctg tgaacgaaaa acctaagtgc tttaatagta
     2941 aaattcctac aaagtagtac ggtaatccag atagaaacat attcattccg tataaattaa
     3001 aaatcttctt actcataagt tacaaactgg gtctctaaaa tattttggac tcttctcctt
     3061 aatcaagtta acatagcagc caccctcgca aatttttaac aatccacaag ataaacactt
     3121 agaattcttc gttctaaaag aacgaatccc tccatacaac ggatcatcat accaaacatc
     3181 taacaaatct ttttcaaagg cattctgctt agtttgatta actcctaaaa aagcaatgca
     3241 aggcaagata tccccattag acattatttc catcttagta tattttgcac gacatccata
     3301 atacatttcg ccaaactctg aaaattcaat tgaattattt atcaactccg gataagcggt
     3361 gaaaagatga catccctcag tagcaaaatt taaattagct tcccgttgag ttatataatc
     3421 tgtaacatac tcattcaacc ttctcaaatc agctaaatcg tattttttct ttattttcgt
     3481 atatcctgtt acctcagaat aattagctac tgaaaatcta tctattttat tctctataca
     3541 aaaatcaacc aattctataa tctgctcata gctttgcttt gtatacactg cattaattct
     3601 acattttttt ccaacctctt taaagtactt cgctaattta atttgtctat caggtctcac
     3661 ccccattaat tcaaaattta atttaggatc taaagtctgc aaagataaaa ccggtgtaat
     3721 atatttagat ttagctagaa tttccactgt acttttcttt attaattggg cattagttgt
     3781 tatagtagtc tttatcttca gttcttcaca agctatcaac aaattatcaa tatcaaaata
     3841 tctagtcggt ttccctccta aaattgaaac acttaacact ccattatctt ttgcttggcg
     3901 caaaattctt tcccaatctt tagcaggttt ggcatttcta tcttcacgat ttgctaaaaa
     3961 acaaaaacca cattttaaat cacagtacat actggggtat attactagtt caagcggaaa
     4021 actcaatatg ttatgttttt ttaattttgc tacatgcttt ctcgcatttt gaagagtctc
     4081 gtcaggattt ttcgatgatc cctcaatatt attatcagaa tagatattta ataagagtac
     4141 tcgctctagt ttccctgctt ttatttcttt cttaaaaaag gacgtagcaa tttcaaaacc
     4201 atgattttga accaaataaa gaaaataagc ttcactctca tctaactcaa ttcggtcaaa
     4261 agttacttta tttatcaaaa ttccaccaaa cttttctagt ctaaataaaa aatcttctga
     4321 aattgtcatc atattgaata cctttctaaa aaagcagagg aaaatatagc ctctgcttaa
     4381 cttatgggat aaattacttt atcactccca gccgtcacct tttgccatca ccttccagcc
     4441 gtcacctttt gccattgaac tagactcaag gactttttca agctctttag acatatttgg
     4501 tactcctttc gaatatgata ctgtgattat atttcttttc aacacttaca ataaaatatt
     4561 cccatatttg cattttctaa ctactagcta aaattttttc taaatgtcct tcataagtct
     4621 ttgctaagtg atgacttcct gctaatttca tcgctccaac acacttcttc atttcaataa
     4681 ttgctttcac atttccatcc tctttatatt gataaagatt ttgtgcatac ttaaagacta
     4741 aacgttcata tacttctgtc tcaataaaaa agcattgatt tagctgcttt tcaaaatata
     4801 aagcatccat aaatttttct ctttcaacac atgtaatata tccatttaaa agcatcgttg
     4861 aaattaatcg tctgttattt ggaatttctt tgtaaaaatc agaacgccta aacatttctc
     4921 ttgctaagac catgaaaaca tcatgattta atacatctaa agtattcgag aaaatcaata
     4981 actcatagta cccccagtat tctacactaa agagataatc tgttaaatat gtcaaatcat
     5041 cctttgtata gtaagtttct cctgataaat cctgtagacg aattttcaat aaaataatat
     5101 tgatttgatg aaatttttct cgcctatctt ccagttccat ctgagaataa agtaattttt
     5161 tcataccttc tacgtcacgt gttgacacaa aatgacgtac tttcgataac agttcgttta
     5221 actcatctct atgaaaatca tggaccgcat acataaattc atctattggc atattgattt
     5281 catctaaaat aaacatgaac tttgaaatcg ttaaatctgt ttctcctttc tcaaatcgag
     5341 agagctgaga cgttgatata ccagcctttg cgacgtcttt taatcgtaat cctctcgatt
     5401 ctcgaaactt tttaaaaatt tctccaaatt ttttcatact acacctccat cacgcatata
     5461 tgggaataat tttcatttgc tttcatcata tcatacaata aagaaaaaca aaagtgagga
     5521 ttatcacatg aaaaagcaaa ttttactaac acttcttctt gtcgtatttg aaggcattat
     5581 cgttatcgtc gtgggataaa gagtctggga caaaagtcct ttagctccaa aaagcaacgg
     5641 cataatgtac tgaccccaaa aagttagaca aataatttaa gtaaaggatt tagttctgta
     5701 ttgtacagga ctgagtcctt ttagttttac cttaatgcgt ttgttgttgt aataattaat
     5761 atagtctgca attgcttgtt ccaaatgctc aattgactta aacgtcttct cataaccata
     5821 aaacatctca gacttaagaa tgccaaagaa ggattccatc atgccgttgt ctggactatt
     5881 gcctttacgt gacatggatg gttggattcc tttctcctct aaaaaatgat gatagaaatc
     5941 atgttgatat tgccatccct ggtcactatg gagaattgta tttttgtaat gtttctctgt
     6001 aaaggcttgt tctaacatag ctttcacttg tatcaagttc ggtgacttag aaagattgta
     6061 ggcgataatt tcactattga agccatctaa aattggcgac aaatagagtt tttggctgct
     6121 tgctggaatg gcaaattctg ttacatctgt gtagcatttt tccaatggtt tggatgcttc
     6181 gaactggcgt tggatgagat tctctgcttt cataccaacc tctccttgat atgaagaata
     6241 cttacgttta cggcgaattc tagcggttaa accaagtact ttcataagac gttgaactct
     6301 cttatgatta atcacaattc ctcgatttct caattcaaga gtcattcgac gatagccgta
     6361 atttccttta tgctcagtaa aaatggcttg aatttcagct ttaatgtcat aatccttatc
     6421 attttgatcc agctgtttta agtggtaata ataggttgaa cgagcaagct taataatctt
     6481 tagaagcata tctaaagaaa actcagttac caatcctcgg acaatttccg tttttcttct
     6541 tgctcttttt cttccctcaa tcggagttct ctcaactttt taagaactgc attctccgct
     6601 ctaaggtact cattttctgc ttgaagacgt tccatttctt ccagtttttt ctttggctta
     6661 cgtcccattt tagataacct tcctcttgtt ttctcaacaa tagtataccc gtttttctta
     6721 tagtgtgcga gccagttagg aagcgtccca cgatttggga gagcatattc aagagaaact
     6781 ctatcttgag aatagccttt atataggact ttatcaatca tttcttgttt taattcagga
     6841 gagtagtaac gattctttcc ttttttagcg atttctattc cgtatcgatc aatcaattta
     6901 atcatgtagc taagattaga aatgtttatc ccaaatttat ttgaaagctg atctaagcta
     6961 tatccttggt ttctaagttc atagatttga accttatctt cataagtcaa tttcataata
     7021 aaaacacccc gaaagttaga ttttttctgt ctaacttttg gggtgcagtt cataaaaccg
     7081 ttgctttttg catgattgtg atagacttgg tgaaatagaa ttgaccaaaa atcttctgaa
     7141 atataacaag agagtgactc gaatttaaaa agctagagtt ccacaattgg aaatctctag
     7201 cttttttgtg actgagaact ttttgtccca gcctctactt tctactgact actatcctgc
     7261 atgccctaag tcgagataga gaatatctcg cttagtggca tactctagcg catgttcaac
     7321 agcctcaaat aaatctgaag ctagaaacct tttcgtaaag acggtttcgt ctttacgctt
     7381 aaatttcgca acataactat gtttagtcat tttttctcct tctaatattc atattgtcct
     7441 ttaacaccac tatagatcca gtaaactgct ttatcataaa cttgtttaaa ggagatacct
     7501 aatcgattgg ctacatcaag aattgaaatt tgcttacatt cctctatatt cataaaatat
     7561 catcattttg tcgtagtatt cggcaatgat ggaacagatg aggattcttc taaagtttta
     7621 ggagttgcct tatctagatc atctaaccca gatttccaaa cctgtacttg gttgaccaat
     7681 aacttaccag gtagtttcga atagttcaaa ttaaccgttc tggtttctgt ttggtttgtc
     7741 tttgattggt tggcattctt taaatcagat acataagtta cattataaga gaccatggca
     7801 atggcttgat tcgtagtctg attgacaaag atatctgctt tttcaaaatg ataatccaaa
     7861 atatagtcct tatacacttg gttcatggca tcattttgac ttgtcaattc ttgagaatag
     7921 gccgattcag tcatataagg ttgaatacgt gtattatttt cccctagttt ttctttcgta
     7981 tagtactgtg tcaaaaattc ttttacagta tctgatgata aaatacttgc tttatcttct
     8041 gcttgtttgt cctctacaag tttagctgca gccaattcga tttcttttcg actttgtttg
     8101 gcagtagaat gttgaccaat agaattagca gtaagttgtg gtgttgatga ggtggatata
     8161 ctaaaaaatg aggaggaaat tgataattac ttcacctagc taaaagttca acgaattagg
     8221 gagacattag gtagcctcat attactttga ttagtttttg ctataacatt gtcaaatatg
     8281 atgacaaaaa aatccgtccg cactttttta cgagtaggac gaattaaata tgttatacaa
     8341 accatcagct ttttaacaat tctacataag gtagttgttg atgcaactac cttttttcta
     8401 tgctgattag aacaaatttg acatggctac aactgcgatt atctgatata gagtattata
     8461 taaactgatt cctcctaccc cttatccaca attttaatac ggctactgcc atcgtgcgac
     8521 ttgatgataa ctagttgctg agcaatacct tctttcatat cgtctacgtg gctgatgaca
     8581 ccgaccatgc ggttttcacc gatttgttcc agaacagaaa tggccttggt cagggcttcc
     8641 ttatccagtg agccaaaccc ttcatcgatg aagagagctt caacaacggc acccttgctg
     8701 gtattttgga caacttctga gagggatagg gcaatggcca gtgcagcgat aaaggtttca
     8761 ccaccagaca aggatttaac ggagcgttca ctacctgtca gctggtcata gacgttgata
     8821 tccaaaccga agtgatcacg cgccctgcgt cctttctcac ttagaacaaa ggaatagcgg
     8881 ttatccgtta atagtccgat gtagttagca ttggcatagt ccaagatttg ttggaaatac
     8941 tgacggataa cgtagacctc aagattaaga cgaccagtta gagcagtatt ttctccctta
     9001 accaccttaa ccaaatcact gagttcttgg tgggccttaa aggcctcttg gttactgtct
     9061 tgaagggttt tagccgcttg gtaggtagcc gtcgcatcct taagtccctt ttccatgaca
     9121 gaaaactgag cgagctgcct atcatagatt tcctgacaat tctgtactgc ttgcgctaga
     9181 ctatcgagat ctggttgttc ttgattttgg agaagctctt gccccttatg aatctgcgcc
     9241 tgtaattctt gtttgagcgt tgcataggtc gttaatttgg cctgaagcat aggaatagct
     9301 tgattattta cctcaataag ccagagttcg acctgctcta agtcattagc gagggctcct
     9361 tcagccttga gactttgctc taattcagca gataatcgct taacatcttg atttacctta
     9421 tctttagact tagttatact ctcaatctgc ccctttattc ctttaatgtc ggcatgaagt
     9481 tggttgtagg cttcgctatt ttccttgact tgcttattgt agaggttcag ctcctgatga
     9541 gcaagggaaa tccgttcttg atatacctca acagactcaa gttctggatg agcttcctgc
     9601 aggtcctcta ggcgttcttg agcttggtca agcactgcct tggcctcttg ataggtttta
     9661 gccaaatctg tcgctttttt ttgagcctta cctagctcat cttgatatcg gatataatct
     9721 gtctcttcct tatcataacg tttttgtaac tcttgataat actgctcaac cttcaggagt
     9781 agggcttgcc cacggtcagt ttcatagtct atcgaaaaat caaaatcaaa ccgtccctta
     9841 acgtgctctt ctaattcttg atagtgcttt tcaagagttg ccttgacttt agccacttgg
     9901 tcaagcaaat cctgacgttt agatgcaact tcactcaagg tagcctgacg atttgataaa
     9961 gtagcgactt gcttttcttt ttgagcttga agcttctcca cctgatccat gagatttttc
    10021 aaggccactt catcagcctg tgctccacca acattagggt gttccagagc accacaaacc
    10081 atacaaggat gcccctcctc taactctgcc tgcagttgga caataatgag ttgacggcgt
    10141 gaaaccaaag tccttcttaa ctcctcttcc aattctttga gaatttcttg agcttgatca
    10201 atatcaaaag ataacgtttg atgacgtttt tcggtctttg tcaactcctg attcaagttc
    10261 tctatttctt tcaggtcctg agcaagttga ttctccacac tgtagcccac aatctggaag
    10321 agtttttcgg cctcatgtaa actctctaaa ctaagacgat tagcctccaa gtcagacaag
    10381 gacttgttaa gcatctcaat ctcttttcta gcctgctgat aggtttcttc caactgcttg
    10441 tagttagtca ttgaacgttt gattttctcc tgttcttggg caagactctg ggcatagata
    10501 atatcctctt tccaagtttc aagctcctct tctttttgaa gaaaatcctt agattgaact
    10561 gcgagttcct ctttttgagc cttaacatcc tcaaacgcct gacgcttttc acttaatact
    10621 tcttgagcaa tgtcaaggtc ctgctctaat tgcatcaact gtttccgata ctgcttcaag
    10681 gtccgaatgg tttcctgcag accttgagca aactgtaatt cctccagatg cacttttgcc
    10741 tctgcctgtc cttgagcccc ctcctcaatt tccagacggt aacgttcctt ggcttgctcc
    10801 acttcttgaa aaatctttgc caaatcttgg gcagtttgca agctcttctg cagttgtgcc
    10861 aaatcctcgt gggcagcctt caagatactt ttttgcttcg taacattttc ttgacgctga
    10921 gacaaaaact cttcaagacg tgtcaatttt tcagaggctg gcgtttgctc caagacggat
    10981 aattcttcct cagaccaaac ctgactggca aaatgaccat ctagctgagc ctgacgcttt
    11041 tccatatcct tattactctg acgaagacgc tcttccaagc tcttttgaaa atggtcaaaa
    11101 atacccgttc caaagatttt ctttaaaatt tgagtcttgg tcttagaatc ttctttcaag
    11161 aaacggctga aatcattttg tggaaggaga ataatctgtt tgaactgctc agcattgagc
    11221 cccaaaatct gctcaatctg gtcactcact tccttgatct tatccccaag cttttcaatt
    11281 tcctgaccac caatcttatc cacaatgact agagaagccg tcgccttttg catggtagtg
    11341 cccccaccct gcttggccct ctcttgctgg agaactcggt caatgcgata aaggtgattg
    11401 ccttgttgga aatagaaagt caccttggtc aaatcatcct ctggaccagc gaaagttgac
    11461 cgcatctcct caacattacg atcaccactg gtcgtagcaa acaaggctac cgtcatggca
    11521 tcaaagagag tactcttacc agcccctgta tcccctccaa tcaaaaagag gggagcatgg
    11581 tcaaactgag tgaaattaat aacttcctta cgatatggtc caaaattggt caattctaac
    11641 tggactggtc tcattgtcga ctcctctcaa tctcctcaaa aacactttcc acaagggcag
    11701 tctgtctctc agataagaca tcgcccccag ttactgtctg gtaaaaatca aatacgattt
    11761 cctggggcga ctgcatttcc aaatctttta agtgctgatc aacggtcaag ttttcttccc
    11821 taacatcacc cagacgactg aaagtaattt ctacaatgtc tgtcccataa atctcttcca
    11881 gtcgggcacg cacattgata ccctctaatt ccttacgact agacagttga atatcaaagg
    11941 cgaaccaggc tttttgacaa ggttgattct tataaaattc aggtgacatc aaggtttcaa
    12001 aagattcctg taaagccaca atcggccgtt taacctctag agtatggaag gtctgagaca
    12061 tatcaccaga cgcatccaat tcaagaatat agacaccctt ttcttcctta cgcttggctt
    12121 ctttgacatt aaaggcgact ggactgcctg aatattgcac gcgcttggta ggactagcaa
    12181 aacgcgtatg gatatgccct aaggcaacat aatcgaaaga cttgaaaagg tcactggtca
    12241 cattggtaag accacctacc gtattactgg tttcagacaa catcaattct cgaagaccct
    12301 gaccatcgct atcatccttc ttagaaaccg caaaatgcgt caccaagaca tgagctttgt
    12361 caggatcaaa agctttttcc atatcctcaa gaatgtaggt caaggcatca ccaatcccct
    12421 gaatttcctt tccctcatca tccttatagt aaatacgagc atcaatagga tcgataaaag
    12481 gcagcagaaa aatctggcaa ttctccaact caatgggctc aaaagcctcc tccaaacgtg
    12541 tacttaaatg aaggccctga tgttgaaaga agtcacgccc aaaatgtaaa cgttcagccc
    12601 catcgtgatt accactaatc gcatagacag gaatctgctc ctccagtacc aagcgggcca
    12661 aggtcttatt aaaaagctta atcgcatcca cagggggcac cgcacggtca tagaggtccc
    12721 cagaaatgat aaccccatcc actttttcgc taatagccaa atccacaatt tgttgaaaag
    12781 cccactcctg ctcctccaac aaagaccagc cattgagggt tcgtcctaca tgccaatctg
    12841 acgtatgtaa aaacttcat
//
