LOCUS       c00049_JAHRBH0..       22425 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHRBH010000049.1 Streptococcus thermophilus strain Douc24
            Contig_049, whole genome shotgun sequence.
ACCESSION   JAHRBH010000049
VERSION     JAHRBH010000049
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:01:38
            Original ID  :: JAHRBH010000049.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 34816
            Orig. end    :: 57241
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22425
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[44816:47241]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12425
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..22425
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22425
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(457..1551)
                     /NRPS_PKS="Domain: Aminotran_5 (2-349). E-value: 2.9e-44.
                     Score: 143.2. Matches aSDomain:
                     nrpspksdomains_ctg49_40_Aminotran_5.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg49_40"
                     /transl_table=11
                     /translation="MTIYNFSAGPATLPKPVLEKAQAELLNYQDSGMSVLEMSHRSPEF
                     DKIIKDAEATLRELMAIPDNYKVIFLQGGASTQFTMVPLNLAQGKKAYYLVGGSWGKKA
                     YTEAVKLSKTIPFEPILLASSEDTVYDHIPSFDPSTIDPEAAYVHLTTNNTIEGTSIYD
                     LPDTNGVPIVADMSSNILAARYNVEDFALIYAGAQKNIGPAGVTVVIVREDFLNDQPQL
                     SAMLDYRIQAEAGSLYNTPPCFNIYISKLVFDWVKNEIGGVDKMAEIQREKSGLLYDYI
                     ESSDFYTNPVKDAKDRSVCNIPFVTPSKDLDAKFVAEADALGFKNIKGHRSVGGMRASV
                     YNAFPRQGVLDLIDFMKKFEDENK"
     aSDomain        complement(505..1545)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg49_40_Aminotran_5.1"
                     /evalue="2.90E-44"
                     /label="ctg49_40_Aminotran_5.1"
                     /locus_tag="ctg49_40"
                     /protein_end="349"
                     /protein_start="2"
                     /score="143.2"
                     /tool="antismash"
                     /translation="IYNFSAGPATLPKPVLEKAQAELLNYQDSGMSVLEMSHRSPEFDK
                     IIKDAEATLRELMAIPDNYKVIFLQGGASTQFTMVPLNLAQGKKAYYLVGGSWGKKAYT
                     EAVKLSKTIPFEPILLASSEDTVYDHIPSFDPSTIDPEAAYVHLTTNNTIEGTSIYDLP
                     DTNGVPIVADMSSNILAARYNVEDFALIYAGAQKNIGPAGVTVVIVREDFLNDQPQLSA
                     MLDYRIQAEAGSLYNTPPCFNIYISKLVFDWVKNEIGGVDKMAEIQREKSGLLYDYIES
                     SDFYTNPVKDAKDRSVCNIPFVTPSKDLDAKFVAEADALGFKNIKGHRSVGGMRASVYN
                     AFPRQGV"
     CDS             complement(1706..2140)
                     /locus_tag="ctg49_41"
                     /transl_table=11
                     /translation="LTFLLPLQMEKLDLSLMQGTTLSAVGLITKVNEILASLDLKDGLL
                     AFKAINAKKEAVYPIFETYCRNLAITILNLQTIFDMETFVLGGGISAQSILIEEVNRQF
                     DKVHHEIDFIGKIIKRPKIVACHHHNGANLIGAAYFLKQG"
     CDS             complement(2103..2375)
                     /locus_tag="ctg49_42"
                     /transl_table=11
                     /translation="VIYHGGLLRFFHGFRVKETLQAKYHFPVAALNDGKAAALAELATG
                     HLKGVTNGAALVLGSGLGGGIIINGKLFQGGRRVDLSPSSSNGKT"
     CDS             2647..3042
                     /locus_tag="ctg49_43"
                     /transl_table=11
                     /translation="MTKFLHTCVRVKDLEASLQFYQEALGFKEVRRNDFPEYKFTLVYM
                     QLEDDPDYELELTYNYDHEVYDLGNGYGHIAVGVDDLEATHQAHKEAGYNVTDLSGLPG
                     KPKMYYFITDPDGYKIEVIRLAQFLEK"
     CDS             complement(3086..3532)
                     /locus_tag="ctg49_44"
                     /transl_table=11
                     /translation="MTAYGYIIVKTLITKVEPDAEVKQSTNEINAAQRKRVAAQELAEA
                     DKIKIVTAAEAEAEKDRLHGVGIVQQRKAIVDGLAESIAELKEANVGMSEGHIMSILLT
                     NQYLDTLNTFADKGNQTLFLPNNPNGVDDIHTQILSSLKVDNKK"
     CDS             complement(3948..4388)
                     /locus_tag="ctg49_45"
                     /transl_table=11
                     /translation="MTPQEMWNAYKKINSSIGDEIDAWAFGVEADLLADLVLKGEKTAT
                     ASAYDLYALADEALPQEGTFDIILDSQDQAVCIVEITKVSVQPFHQVSADHAFKEGEGD
                     KSLAYWRQVHEDCFAEWLREAGMTFTPNSKVVLEEFRKVYPL"
     CDS             complement(4400..4564)
                     /locus_tag="ctg49_46"
                     /transl_table=11
                     /translation="MNLQAFVNDNYDVLDISTGQTEIIQDFISIQEISETLNYYMENML
                     KLNCKGKFS"
     CDS             5053..5418
                     /locus_tag="ctg49_47"
                     /transl_table=11
                     /translation="MKKPKFEFYTRLNGHTEFLEFLQTIPIKDKQKLLATIATMQEHGL
                     LVAQRMEWVKKLDDDIFEIRSKVASNIQRALYFHVINERYIITHGFTKKTQKTPQSEIK
                     HAKDLKKEFEDNNHDHN"
     CDS             5405..5680
                     /locus_tag="ctg49_48"
                     /transl_table=11
                     /translation="MTTIKFDDFLENELADKNFKEGFLTEKAILESAIAVSDARQTAGL
                     TQRELASLSHVPQSTIARIERGHNTSIETMSKIALALNKNLTIKIS"
     CDS             complement(5750..6052)
                     /locus_tag="ctg49_49"
                     /transl_table=11
                     /translation="MSQKYTKEFKETIVQLHETGYPVSDLVKEYGVANQTIYKWLQLYG
                     KSGKSKAENVSLHELQQMRKEMAQFLIKLYQSDEVVGLVDVKNFEFHLSGPLFNH"
     CDS             complement(6639..7901)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 105.6; E-value: 4.4e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_50"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNSYGVSLLLACPIVLSSNVLAHFLSDEITSNIIPLTLYT
                     FIIMGIFPIYESSKMLLQGTENEKFVLQVSIWINLICVAIMILFQFLRVQTYFSLYFIY
                     GLSLTVLSIIFLQHASSEKII"
     CDS             complement(8131..8220)
                     /locus_tag="ctg49_51"
                     /transl_table=11
                     /translation="MKEHFVIRGKRDFIVNKVADEYIGYDLLD"
     CDS             complement(8217..8828)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_52"
                     /sec_met_domain="TIGR04085 (E-value: 1.7e-15, bitscore:
                     49.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5.1e-13, bitscore: 41.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNDMLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERIS
                     KGEFKVKFKIVPPNESDVFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAGV
                     RACSINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLRSITFDDISGKCS
                     ECPLPWCGGGCRCSALELDGTLLGSDLACFYEQKGGGVVV"
     CDS             complement(8913..9968)
                     /locus_tag="ctg49_53"
                     /transl_table=11
                     /translation="MFLSGLPYYFVGILLLKHLGFSFTEIATLSVITELCGSVFDIPLS
                     YISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESLSSGVLISYNFEI
                     IDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVFVIFSLLYLIGLP
                     EIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFLNEQGLSLDMLGI
                     ILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLLMRVLNSNYNNHF
                     YYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNYLIFGIVALCCLV
                     SYSFSNREKRT"
     CDS             complement(10001..11320)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_54"
                     /sec_met_domain="PF04055 (E-value: 7e-20, bitscore: 64.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.8e-07, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2e-13, bitscore: 43.1,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 1.4e-24, bitscore:
                     79.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEIATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQNARKHVAKLKKHNILS
                     FPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGEPT
                     RYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDPKLNFEL
                     MGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEV
                     TGYTKIKKKYDLDDLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEF
                     GEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSF
                     RTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             complement(11390..11482)
                     /locus_tag="ctg49_55"
                     /transl_table=11
                     /translation="MSKELEKVLESSSMAKGDGWKVMAKGDGWE"
     CDS             complement(11565..12425)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_56"
                     /sec_met_domain="TIGR01716 (E-value: 5e-51, bitscore:
                     165.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGEIFKKFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMELED
                     RREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYYELLIFSNTLDVL
                     NHDVFMVLAREMFRRSDFYNEIPNNRRLISTMLLNGYITCVEREKFMDALYFEKQLNQC
                     FFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSHHLAKTYEGHLEK
                     ILASS"
     CDS             complement(12665..13501)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 266.7; E-value: 3.2e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg49_57"
                     /transl_table=11
                     /translation="LVTEFSLDMLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIF
                     TEHKGNYGYRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAE
                     NLIQRQFEASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQV
                     KAMLEQAFTEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESF
                     FGILKSEMFYGYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             complement(13495..14061)
                     /locus_tag="ctg49_58"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYTIVEKTRGRLSKMGRKPKKKLEEMERLQAENEYLRAENAV
                     LKKLRELRLREEKEQEEKRKLSEDW"
     CDS             complement(14240..14398)
                     /locus_tag="ctg49_59"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             complement(14551..15192)
                     /locus_tag="ctg49_60"
                     /transl_table=11
                     /translation="MLNKVKTKALISVGAVATTSFILMMGYTAGQHSTAKQSRKEIELA
                     AAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTSQN
                     DAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTETRT
                     VNLNYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPSLPNTTTK"
     CDS             complement(15291..15869)
                     /locus_tag="ctg49_61"
                     /transl_table=11
                     /translation="MYNEVKRFYLFRRRRWADTLFDTLYHVIFILGFYSLLRGNSDFQL
                     SYFYYYFILTHVVSLGNEELEYEIRSGQSFGTQYALQSVYRIYLQRAVVYFVWLSLIFW
                     IALLLIRQDLLPHFSLKVISFQELLVVLVAFLIFIGYYFVMIRLTIRFQRISVLVDFLN
                     TVLLFYSGLVFPVVSFGNLKKLFDWLIRN"
     CDS             complement(16155..16430)
                     /locus_tag="ctg49_62"
                     /transl_table=11
                     /translation="MHLPFGIDKIAARIQLRLLQSEIVVETKTKDNVFVMMNVATQYRV
                     NEQNVTDAYYCFAWLPWFSRLPFLLTGSLHLLPFFCPLWLLRPFMV"
     CDS             complement(16484..16588)
                     /locus_tag="ctg49_63"
                     /transl_table=11
                     /translation="MQAAFLFLLILFLIILGILISMLYVVRQQSVASQ"
     CDS             complement(16778..17845)
                     /locus_tag="ctg49_64"
                     /transl_table=11
                     /translation="MRKLYQFLSGILAIIFFLWGISAYMQSRTGSASDKLVIYNWGDYI
                     DPDLLTKFTKETGIKVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMVKEDLLVK
                     LDKSKIHGFDQIGSSFKGLSFDPNNDYSIPYFWGTVGIVYNTKLVKKAPQHWNDLWSPE
                     YRNQIMMVDGAREVIGFSLNSLGYSLNTKNMTELRLAETKLNSLTPNIKAIVGDEMKGY
                     MIQGDAAIGVTFSGEASEMLDKNEDLRYVVPSEGSNLWFDNLVIPKTVKHEKEAYAFIN
                     FMLKPENAAQNAEYIGYATPNEAAKTLLPKSITNDKAFYPSESTIKNLEVYNNLGKKWL
                     GIYNDIYLQDKMYRK"
     CDS             complement(17838..18617)
                     /gene_functions="transport (smcogs) SMCOG1069:putative ABC
                     transporter permease protein (Score: 156.4; E-value:
                     1.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_65"
                     /transl_table=11
                     /translation="MKKFANLYLALVFVIIYLPIFYLIAFSFNSGGDMNSFTGFTLDNY
                     QSMFSDSRLMLILAQTFFLAFLSALLATIIGTFGSIFIYESKQKQQTGILSLNNVLMVA
                     PDVMIGASFLILFTWIGFQLGFVSVLLSHIAFSIPIVVLMVLPRLKEMNRDMVNAAYDL
                     GATQWQMLREVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLAVEIYSRARK
                     GISLEINALSTVVFLFSILLVIGYYMITQERKEEHDA"
     CDS             complement(18614..19408)
                     /gene_functions="transport (smcogs) SMCOG1067:putative ABC
                     transporter permease protein (Score: 200.3; E-value:
                     6.4e-61)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_66"
                     /transl_table=11
                     /translation="MKKTASLFSVPYLLWLLLFVVAPVLMLLYQSFFDISGNFTLDNYG
                     TFFSSWTYLRMSFNSVLYAAIITLVTLLISYPTAYLLTRLKHKQLWLMLVILPTWVNLL
                     LKAYAFMGIFGQQGGINAFLGFFGIAPMQILFTDFSFIFVASYIEIPFMILPIFNALDD
                     LDENIVNASKDLGANDWQTFTKIIFPLSLNGVRSGVQSVFIPSLSLFMLTRLIGGNRVI
                     TLGTAIEQHFLTTQNWGMGATIGVVLIVTMIAIMWLTKERRQ"
     CDS             complement(19392..20546)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 235.2; E-value:
                     1.3e-71)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_67"
                     /transl_table=11
                     /translation="LTNPIIAFQNVSKVFEDSGTQVLKDINFELEEGKFYTLLGASGSG
                     KSTILNIIAGLLDATSGDVLLDGKRINDIPINKRDVHTVFQSYALFPHMNVFDNVAFAL
                     KLKKVPKKEIEERVKEALKMVQLDGYQKRSIQKLSGGQRQRVAIARAIINQPRVVLLDE
                     PLSALDLKLRTEMQYELRELQKRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQSGTP
                     VDIYDEPINHFVATFIGESNILPGVMIEDYLVEFNGKRFESVDGGMRPNEPVEVVIRPE
                     DLQITLPEEGKLQVRVETQLFRGVHYEIIAYDNLGNEWMIHSTRKAIEGEIIGLDFTPE
                     DIHIMRLNETEEEFDARIEEYVEMEEPEDGLINAIEEERHEENS"
     CDS             complement(20591..21493)
                     /locus_tag="ctg49_68"
                     /transl_table=11
                     /translation="MLDELKEDLVGIDIRFDEPLKRYTYTKVGGPADYLAFPRNRYELS
                     RIVKFANKHNIPWMVLGNASNLIVRDGGIRGFVIMFDKLNGIAVNGYQVEAEAGANLIA
                     TTKVACFHSLTGFEFAAGIPGSIGGAVFMNAGAYGGEIAHILVSAQVLTKDGDIRTIDA
                     RDMRFGYRRSVLQETGEVIISAKFNLKPGDYEQIKHEMNRLNHLRELKQPLEYPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSTKHAGFMVNVDQGTAKDYEDLIADVIAKVK
                     ENSGVTLEPEVRIIGDKLN"
     CDS             complement(21682..22173)
                     /locus_tag="ctg49_69"
                     /transl_table=11
                     /translation="MTKVYLSLGSNMGNRQDYLKKAVESLDRLLETEVKAVSSYYETAA
                     WGLTDQADFLNLALALDTQLPAESLLSACQAIEKDLDRVRHEHWGPRTVDIDILLYGQE
                     IWGTEHLKVPHPLMTQRAFVLVPLLEIAENLVEPQTGQAYKKYLSQIDTSDVRKLEQVD
                     "
ORIGIN
        1 aatagacata gccaagtttc tccaaaatgt gctgcatgac aagattcttt tcatgcgtgt
       61 cgcaacgaaa atcatgagcg tcagttccct caataagacc ttgaataaag gtttgagcat
      121 ttttctgtcc cgtaaattct cttaaaaccg caattcgatg aaaggtaaca tagcgcttat
      181 tatgatgctt ccaatctcca tcatagattt tttcgtaggc gggctctcca tcagtaacca
      241 ccgcagcata agaaacaatt tgaccgtcaa tgataccgac ataggcctgt cctttaagaa
      301 catcatcaaa gatgatttct tctgtaggat aaccatcagc cccttgccat tgagaactac
      361 cagcttccgc taaagcaatt ctagcactct caatcacggt catgatagca ccaatttcat
      421 ttgggaaagc ttgtctaatt tccatctctt tcctaattat ttattttcat cttcaaattt
      481 cttcataaag tcaatcaaat caagcacacc ttgacgcggg aaggcgttat aaacactggc
      541 acgcatacca cccactgaac ggtgtccctt gatatttttg aaaccaagag catctgcttc
      601 tgctacaaat ttggcatcca agtctttact tggtgtgaca aatggaatgt tgcagacaga
      661 acgatccttg gcatctttaa caggattggt gtagaaatca gatgattcga tatagtcata
      721 aagaagacct gatttttcac gttgaatttc cgccatctta tctacgccac caatctcatt
      781 ttttacccag tcaaaaacga gttttgaaat atagatattg aaacatggtg gtgtattgta
      841 gagtgatcct gcttcagctt gaatacggta gtccaacatg gcagacaatt gtggttggtc
      901 gttaaggaag tcttcacgga cgataaccac cgtcacaccc gcaggtccaa tatttttctg
      961 agcaccagca tagataagag caaaatcctc aacattatag cgagctgcta agatatttga
     1021 agacatatct gctacaattg gcacaccatt agtatcaggc aaatcataga tagatgttcc
     1081 ctcaattgta ttattggtag tcaagtgaac ataagcggct tctggatcaa tcgttgaagg
     1141 atcaaaactt gggatatgat cgtaaacagt atcctcagat gacgccaaaa gaattggttc
     1201 aaaaggaata gtttttgaaa gcttgacagc ttcagtatag gcttttttac cccatgaacc
     1261 acctacaagg tagtaagctt tcttaccttg agcaaggttc agtggaacca ttgtgaattg
     1321 cgttgaagcg cccccttgca agaaaataac cttatagtta tcaggaatgg ccataagctc
     1381 gcgaagtgtc gcttccgcat ctttaatgat tttgtcaaat tctggagaac ggtgggacat
     1441 ttctagcacg gacataccgg aatcttgata gttaagcaat tcagcttgtg ctttttcgag
     1501 cacaggtttt ggtaatgtag caggtcctgc tgagaaatta taaattgtca taaagacacc
     1561 tccaaaattt taatgggccc attatagcta attttctgaa tattgtaaag tgttaatagt
     1621 aaaaaacgaa cggaattgcc cgttcatcac aaaaaaagtt aggtatttta tatatatttt
     1681 tgcaagtaat cagatttact atccgttatc cttgcttaag aaaataggct gcaccgatta
     1741 gatttgctcc attatgatga tgacaggcta caatctttgg acgtttaata attttaccga
     1801 taaaatcaat ctcatggtga accttatcaa actggcggtt gacttcttct atcagaatag
     1861 actgagctga aataccacct ccaagaacaa aggtttccat atcaaagata gtttgaagat
     1921 tcaatatagt aatagctaga tttcgacaat aggtctcaaa gattggataa actgcttcct
     1981 ttttagcatt aattgcctta aaggctagca aaccatcttt taaatcaaga ctagctaaaa
     2041 tttcattaac tttagtaatc aaaccaacag ctgaaagagt tgttccttgc atcaatgaaa
     2101 gatcaagttt ttccatttga agaggaagga gaaaggtcaa ctctcctgcc tccctgaaaa
     2161 agtttaccat tgattattat acctccacca aggcctgacc ctaaaacaag agcagcaccg
     2221 ttagtcactc ctttcagatg acctgtggct agttcagcca aggctgctgc tttaccatca
     2281 ttaagcgccg ctactggaaa atgatactta gcttgcaggg tttctttgac acgaaaacca
     2341 tgaaaaaatc tcaacaaacc gccgtgataa atcacaccct ccttccgtat caacagtttc
     2401 aggaacacta attgcactgc ctgataaagc tacttcaacc gaagttacta aatgatcaat
     2461 aacatcgaga gccttatcca aggtatgagg ggatgattgc gttggcaaac tcttttcgag
     2521 gacaaggtcc tctgaaacaa gagcagactt tacctgagtc cctccaaaat caattgctaa
     2581 aactagaaaa aacgctatca aaatgctatc atggttttag aaaactagat aaaaggagtc
     2641 tctcacatga ctaaatttct acacacttgt gtccgtgtta aagacctaga agcttcacta
     2701 caattttatc aagaagcgct tggttttaag gaagtccgtc gtaacgattt cccagaatat
     2761 aagttcactc ttgtctacat gcaactagaa gatgatcctg attacgagtt ggaattgaca
     2821 tacaactacg atcatgaagt ttatgatctt gggaatggtt atggacacat cgctgttggt
     2881 gttgatgacc tagaggccac acaccaagcc cacaaagagg ctggctataa tgttactgat
     2941 ctctcaggtc tacctggtaa accaaaaatg tactacttta ttactgatcc agatggctat
     3001 aaaatcgagg tcatccgttt agctcagttc ttggaaaaat aatgaaaaag aagtcagatt
     3061 atctcaactc tggctccttt tttatttatt ttttattatc gacctttaag gatgacaaaa
     3121 tttgggtatg aatatcatcc acgccatttg gattatttgg caagaataaa gtttgattac
     3181 ctttatccgc aaaagtatta agggtatcta gatattggtt ggtcaagagg atagacataa
     3241 tatgtccctc agacatacca acattggctt ctttaagttc tgcaatagat tcagctaaac
     3301 catcaacgat ggctttacgt tgttggacaa taccaacacc atgaagacgg tctttttcgg
     3361 cttcggcttc agcagctgtg acaatcttaa ttttatcagc ttctgccaat tcttgggctg
     3421 ctacacgctt acgttgagca gcattaattt cgttcgtaga ctgcttaact tcagcatctg
     3481 gctcaacctt ggtaatcaag gtcttaacaa tgatgtatcc ataagctgtc atttcttagg
     3541 ctacttgatg ttgaacctca agagcgattt catctttctt ctcaaaaagc tcatcaagcg
     3601 tcaatttagg aactgatgaa cgaagggcat caatgtatga tttaatttga gcctctggtc
     3661 gcatgagttt gttgtctctt gtgccgatga cagctcttct ttcgaaatct taagtagccc
     3721 cttttttatg atatcatatc tcaaaagagc ctattcaaaa gccaaatctc tgtcactttt
     3781 agaattaaaa cgcatctcga atatcccctt taaaaagaga ctgggacaaa agtcctagcc
     3841 tctcaattgt ctttggattg ccgagcaaga cgcaatggtt gagtgggctc tactacgctg
     3901 atttcatcag cttttacagt cctactcaac tgtcccactc tcatgttcta taatggataa
     3961 accttgcgaa attcttctaa aacaaccttg ctattaggtg taaaagtcat tcctgcctct
     4021 ctcagccact cagcgaaaca gtcctcatga acctgacgcc aataggctag ggatttgtca
     4081 ccttcccctt ccttgaaggc atggtcagct gacacttgat gaaaaggctg aacagaaacc
     4141 tttgttattt cgacaatgca gacagcctga tcttggctat ctaaaatgat atcaaaggtc
     4201 ccttcttgtg gaagggcttc atccgctaga gcgtaaagat cgtaagctga agcagttgcc
     4261 gtcttttcac cttttaaaac caagtctgcc aagagatcag cttccacccc aaaagcccag
     4321 gcatctatct catctccgat agaggagtta attttcttgt atgcattcca catttcttgc
     4381 ggtgtcatga gtgctccttt cagctaaatt tgcctttaca atttaacttt aacatatttt
     4441 ccatgtaata atttagtgtc tctgaaatct cttgtataga aatgaaatcc tgtataattt
     4501 cagtttgacc tgtactgata tctaaaacat catagttgtc attaacaaaa gcttgtaaat
     4561 tcatcttatc aatgtttcaa aatcaggttt taacaactgc tttctagcaa aacgagaaaa
     4621 gtttgaaaaa acatcttgct tcatttgctc taacagtttt tgattttcga tactgtcaat
     4681 aattttcaag ttatacataa aattactgtg cagtgaattc aattactatt ataccaaatc
     4741 caattctact ttagttataa tttccattta tttagtgaca tactacaaca ctatccgaat
     4801 atagaaatta atctaaaatt acaagaaata cccaaagtgt tcctttggca tacatatatg
     4861 tcacttagag tttatctcaa ccgtcaacag atggaataaa tttactacta ttttcgcaac
     4921 tattttcaca accaaaacta agattaagaa taaaaaatac ataattacta tatgattgca
     4981 acatagcatt tggataaagt tcacaccatt attcttgaag aaaagaacaa tatatgctat
     5041 catggagata caatgaaaaa gccaaaattt gagttttata ctcggttaaa tggacacacc
     5101 gagttcctag aatttttaca aactatacca attaaagaca aacaaaaatt actggcaact
     5161 atcgccacta tgcaagagca tggtctttta gttgctcaac gtatggaatg ggtgaaaaag
     5221 ctagatgacg acatctttga aatccgctca aaggttgctt ctaacattca aagggcactt
     5281 tattttcatg ttatcaatga acgctacatc atcacccatg gctttaccaa aaaaacacaa
     5341 aaaacacccc agagtgagat aaaacacgct aaggatttaa agaaagaatt tgaggacaac
     5401 aaccatgacc acaattaaat ttgatgattt tttagaaaac gaactagcag acaaaaattt
     5461 taaagaaggc tttttaactg aaaaagctat tttggaaagt gctattgcag tttctgacgc
     5521 acgacaaaca gcaggtctca cccaaaggga actagcttcc ctatctcatg tcccacagtc
     5581 taccattgct cgcattgaac gtggacataa cacaagcatt gaaacaatga gcaaaattgc
     5641 acttgctctg aataaaaatc taactatcaa aataagctaa taatcaaatt aagctctcaa
     5701 aaaagctgat gaaatataaa ttcatcagct tttttatcac atgtaacaat caatggttaa
     5761 acaatggccc actaaggtgg aactcaaagt ttttaacatc aactaaacca acaacttcgt
     5821 cactttgata taattttatc aaaaattgtg ccatctcttt gcgcatttgt tggagttcat
     5881 gaagggatac attttcagct ttagatttgc cagacttccc gtatagttga agccatttgt
     5941 atatagtttg gttggcaact ccgtactctt tgactagatc tgaaacagga tagcctgttt
     6001 catgtaattg aacaatagtt tccttgaact ctttggtata tttttggctc atttggacat
     6061 ctcctttagg tagatactat tctaccaaaa cgtgtccata aaatcatact aacatcagct
     6121 tgaaagtttt cgtctctgtc tgagtacttt tctgcgcctt ttcactcaca tcagacacat
     6181 aaacaacttg ataagaaact tctgcgagag cttcattatt ctccgtatta acatagatac
     6241 gagctgtatc aaagcgataa tctaaaatat agtccttgct tttccttggt gtaatactga
     6301 gtgagaaact tttttaacca gatcatcaga taagacgtct gccttttcct tttgtttctc
     6361 ttttgtcagt agtttgtgag cctatgactg gatttgctta tgcgtatgac tggtcacaga
     6421 ctgagaacca atggtatagc caatcattac gataaaactg gttacagcta gtccacccaa
     6481 gccaattaaa agcctagctt ttattttatt taacatgatt gttgctatct cctttatatt
     6541 aagatagccc catcataaca agattaactt ggaaaagtta tcacaagaaa aaaagattta
     6601 gcctgtaatt ttaagactaa atcttattat attatcattt atataatttt ttctgaagaa
     6661 gcatgttgta aaaatattat agataaaacg gtcagactta aaccatagat aaagtacaat
     6721 gaaaaatatg tctgtactct taaaaattga aataaaatca ttattgcaac acaaataaga
     6781 tttatccaaa tcgatacctg caaaacaaat ttctcatttt ctgtgccttg taataacatt
     6841 ttagaacttt cataaattgg aaatattccc ataataataa atgtgtacaa agttaaagga
     6901 ataatatttg aggttatttc atctgaaaga aaatgagcta agacatttga tgataaaaca
     6961 ataggacaag ctaataacag actaacacca tatgaatttt taaatatgtt ttttaaaaat
     7021 acgttaacct ctcctatttt ctctgcttca ggtaaataga tagaaacggt tgtcgaataa
     7081 acaaaagaag gtacactcac aattgaaagc aattgactaa taactgcata aatagccaac
     7141 aattctactc ctaatctcga catcaaggca tcaaacacca taataaacaa aacactctcc
     7201 agaatttctt gaccaaccaa aggaatacca aatgttatta attcaaattt agttgtagat
     7261 gtaatggata aagccttcaa aatcattgga taaaccataa acaagtaact aagcgatatg
     7321 aaagctaagg atacaatcgt tgatatggct gctcccttaa ttccgatttg tggtaccagt
     7381 acataattta acacaacatc tattaatgaa ctgataagtc caacccacat aattggtttt
     7441 gttttctttt gaactcttaa taaatttgtc agcgaaaagt ttaataatgt caatccgata
     7501 tatggagaca tgaagactaa ataaatggtg gataaggaca atagttgccc tttaaatcca
     7561 tagagctgct tcaagattac atttccaaaa ataatgacaa aaaccgcaaa ggcaactccg
     7621 ataattaaat ctaaggttag atttgatttc aataaatcat caaacctgtt agtttgccga
     7681 ttagagtacg ccttagagct tttaatatta aatgacaaac tgaatgctcc taaaagtcca
     7741 ccaaaagcaa ataagagatt ctgaataatg gaaattcctg acagagcaat tgaggaattg
     7801 ttcacagcaa aatgcaatgc tatctgccca ataattactt gaccaatatt tgttaaaact
     7861 aagggaaagg caaatttgtt aatttctttt gaatctatca tttttcctct ctaaaaggct
     7921 tcaaatgtaa gtaaagatca gatttaacta aatttgcata aataatatgc aaaataggag
     7981 tttcttctaa aaatgaaata attgcctgct tacaatcatt agcagatacc tcataatctt
     8041 gctgtaatag ttctacaatc ttgtctaaag aaaaattttt agaaatgcaa taaagtattt
     8101 ctgctcctat ttcatcaaat gaatagtact ctaatcaagt agatcgtatc ctatgtattc
     8161 atctgctact ttatttacaa tgaaatctct cttacctctt atcacaaaat gttctttcat
     8221 acgactactc cacctccttt ttgttcataa aagcaggcta aatcagagcc cagtaacgtt
     8281 ccatctaatt ccaaggcact gcatcgacat cccccaccac accatggtag gggacattct
     8341 gaacatttcc cagaaatatc atcaaatgta attgatctta gtttattaaa tacagcagaa
     8401 tggtgccaaa tttcgctaaa cttttgttct ttaacatttc cagcaactaa ttcatctata
     8461 ccattcatca agtcacaccc gtatacatct cctttatgat taattgaaca tgctctaact
     8521 ccagcttgac aagatatttc ccttggctta tcaaaattta tatctacttt ttgatgccaa
     8581 acattttcta ataaatctga tctattataa aatgcaagcg gaaaataatg tgtcaaaaaa
     8641 acatcacttt cattaggagg aacaatttta aatttaactt tgaactctcc tttagaaatc
     8701 cgctctgtta aatcaagaaa aacaggatac cattgttttt tatctgctaa aatactaccg
     8761 tcattagccc taccagtagg acaaataacc ataactgaca tatactcaat accaagcata
     8821 tcattcaatc ttatactcta aagaaaatat ctgctaaatt tgcaaacaat tgtgctatca
     8881 ataatttggc aaatgaatta gaaatacaac ttttaagttc ttttctctct gttagaaaat
     8941 gaataagata ctaagcaaca aagagctact ataccaaata ttaaataatt gctcctaata
     9001 ctaaagttat cagcaaaaat accagctagg aaatcagcta acataaaact aatcgaaata
     9061 aacaaattat atactgacca tgatactgct ctattttttt ctattgacat attaaattta
     9121 taataaaaat gattattgta gttggaatta agaacacgca ttaataaaag gattataatt
     9181 tggatgatta gattagtttg aaaaaacatg agtatagcta atactggtaa catcaagctt
     9241 acttcaaact taatttttag ataactcccc aaagccatag atatattaaa cataaatagt
     9301 ataattccca gcatatctag tgaaagtccc tgttcattta agaatatccc tgcataagaa
     9361 ttgctaatca taattagagt tgagaatgct actcctaata ttattaataa ccatggaata
     9421 ttttgaatat tatcgaggct aaaaaatttt tgtttattat tttgttcctt tttaatctcg
     9481 ggtaatccta ttaaatataa taaactgaaa attacaaata caatggatat aataatagga
     9541 taaatataat tcctatgcaa taaaggtgga gatataatcg taataatagc aataaaaata
     9601 tattttaatg tgttgagatt tttcaaaaat gatttatata caacttcgtc atcaattatt
     9661 tcaaaattat aagaaataag aactcctgaa gataatgatt ctgacaatcc aaaaaatatc
     9721 gctgaaatat atattatatt tgattttcca aacaataggc cccataatgc taaaattaat
     9781 aataaatttg aaatagccaa aattttcttg taaccaatct tacttgaaat ataacttaaa
     9841 ggaatatcaa aaactgagcc acatagctca gtaataactg ataaagtagc tatttctgtg
     9901 aacgaaaaac ctaagtgctt taatagtaaa attcctacaa agtagtacgg taatccagat
     9961 agaaacatat tcattccgta taaattaaaa atcttcttac tcataagtta caaactgggt
    10021 ctctaaaata ttttggactc ttctccttaa tcaagttaac atagcagcca ccctcgcaaa
    10081 tttttaacaa tccacaagat aaacacttag aattcttcgt tctaaaagaa cgaatccctc
    10141 catacaacgg atcatcatac caaacatcta acaaatcttt ttcaaaggca ttctgcttag
    10201 tttgattaac tcctaaaaaa gcaatgcaag gcaagatatc cccattagac attatttcca
    10261 tcttagtata ttttgcacga catccataat acatttcgcc aaactctgaa aattcaattg
    10321 aattatttat caactccgga taagcggtga aaagatgaca tccctcagta gcaaaattta
    10381 aattagcttc ccgttgagtt atataatctg taacatactc attcaacctt ctcaaatcat
    10441 ctaaatcgta ttttttcttt attttcgtat atcctgttac ctcagaataa ttagctactg
    10501 aaaatctatc tattttattc tctatacaaa aatcaaccaa ttctataatc tgctcatagc
    10561 tttgctttgt atacactgca ttaattctac atttttttcc aacctcttta aagtacttcg
    10621 ctaatttaat ttgtctatca ggtctcaccc ccattaattc aaaatttaat ttaggatcta
    10681 aagtctgcaa agataaaacc ggtgtaatat atttagattt agctagaatt tccactgtac
    10741 ttttctttat taattgggca ttagttgtta tagtagtctt tatcttcagt tcttcacaag
    10801 ctatcaacaa attatcaata tcaaaatatc tagtcggttc ccctcctaaa attgaaacac
    10861 ttaacactcc attatctttt gcttggcgca aaattctttc ccaatcttta gcaggtttgg
    10921 catttctatc ttcacgattt gctaaaaaac aaaaaccaca ttttaaatca cagtacatac
    10981 tggggtatat tactagttca agcggaaaac tcaatatgtt atgttttttt aattttgcta
    11041 catgctttct cgcattttga agagtctcgt caggattttt cgatgatccc tcaatattat
    11101 tatcagaata gatatttaat aagagtactc gctctagttt ccctgctttt atttctttct
    11161 taaaaaagga cgtagcaatt tcaaaaccat gattttgaac caaataaaga aaataagctt
    11221 cactctcatc taactcaatt cggtcaaaag ttactttatt tatcaaaatt ccaccaaact
    11281 tttctagtct aaataaaaaa tcttctgaaa ttgtcatcat attgaatacc tttctaaaaa
    11341 agcagaggaa aatatagcct ctgcttaact tatgggataa attactttat cactcccagc
    11401 cgtcaccttt tgccatcacc ttccagccgt caccttttgc cattgaacta gactcaagga
    11461 ctttttcaag ctctttagac atatttggta ctcctttcga atatgatact gtgattatat
    11521 ttcttttcaa cacttacaat aaaatattcc catatttgca ttttctaact actagctaaa
    11581 attttttcta aatgtccttc ataagtcttt gctaagtgat gacttcctgc taatttcatc
    11641 gctccaacac acttcttcat ttcaataatt gctttcacat ttccatcctc tttatattga
    11701 taaagatttt gtgcatactt aaagactaaa cgttcatata cttctgtctc aataaaaaag
    11761 cattgattta gctgcttttc aaaatataaa gcatccataa atttttctct ttcaacacat
    11821 gtaatatatc catttaaaag catcgttgaa attaatcgtc tgttatttgg aatttcattg
    11881 taaaaatcag aacgcctaaa catttctctt gctaagacca tgaaaacatc atgatttaat
    11941 acatctaaag tattcgagaa aatcaataac tcatagtacc cccagtattc tacactaaag
    12001 agataatctg ttaaatatgt caaatcatcc tttgtatagt aagtttctcc tgataaatcc
    12061 tgtagacgaa ttttcaataa aataatattg atttgatgaa atttttctcg cctatcttcc
    12121 agttccatct gagaataaag taattttttc ataccttcta cgtcacgtgt tgacacaaaa
    12181 tgacgtactt tcgataacag ttcgtttaac tcatctctat gaaaatcatg gaccgcatac
    12241 ataaattcat ctattggcat attgatttca tctaaaataa acatgaactt tgaaatcgtt
    12301 aaatctgttt ctcctttctc aaatcgagag agctgagacg ttgatatacc agcctttgcg
    12361 acgtctttta atcgtaatcc tctcgattct cgaaactttt taaaaatttc tccaaatttt
    12421 ttcatactac acctccatca cgcatatatg ggaataattt tcatttgctt tcatcatatc
    12481 atacaataaa gaaaaacaaa agtgaggatt atcacataaa aaagcaaatt ttactaacac
    12541 ttcttcttgt cgtatttgaa ggcattatcg ttatcgtcgt gggataaaga gtctgggaca
    12601 aaagtccttt agctccaaaa agcaacggca taatgtactg accccaaaaa gttagacaaa
    12661 taatttaagt aaaggattta gttctgtatt gtacaggact gagtcctttt agttttacct
    12721 taatgcgttt gttgttgtaa taattaatat agtctgcaat tgcttgttcc aaatgctcaa
    12781 ttgacttaaa cgtcttctca taaccataaa acatctcaga cttaagaatg ccaaagaagg
    12841 attccatcat gccgttgtct ggactattgc ctttacgtga catggatggt tggattcctt
    12901 tctcctctaa aaaatgatga tagaaatcat gttgatattg ccatccctgg tcactatgga
    12961 gaattgtatt tttgtaatgt ttctctgtaa aggcttgttc taacatagct ttcacttgta
    13021 tcaagttcgg tgacttagaa agattgtagg cgataatttc actattgaag ccatctaaaa
    13081 ttggcgacaa atagagtttt tggctgcttg ctggaatggc aaattctgtt acatctgtgt
    13141 agcatttttc caatggtttg gatgcttcga actggcgttg gatgagattc tctgctttca
    13201 taccaacctc tccttgatat gaagaatact tacgtttacg gcgaattcta gcggttaaac
    13261 caagtacttt cataagacgt tgaactctct tatgattaat cacaattcct cgatttctca
    13321 attcaagagt cattcgacga tagccgtaat ttcctttatg ctcagtaaaa atggcttgaa
    13381 tttcagcttt aatgtcataa tccttatcat tttgatccag ctgttttaag tggtaataat
    13441 aggttgaacg agcaagctta ataatcttta gaagcatatc taaagaaaac tcagttacca
    13501 atcctcggac aatttccgtt tttcttcttg ctctttttct tccctcaatc ggagttctct
    13561 caacttttta agaactgcat tctccgctct aaggtactca ttttctgctt gaagacgttc
    13621 catttcttcc agttttttct ttggcttacg tcccatttta gataaccttc ctcttgtttt
    13681 ctcaacaata gtatacccgt ttttcttata gtgtgcgagc cagttaggaa gcgtcccacg
    13741 atttgggaga gcatattcaa gagaaactct atcttgagaa tagcctttat ataggacttt
    13801 atcaatcatt tcttgtttta attcaggaga gtagtaacga ttctttcctt ttttagcgat
    13861 ttctattccg tatcgatcaa tcaatttaat catgtagcta agattagaaa tgtttatccc
    13921 aaatttattt gaaagctgat ctaagctata tccttggttt ctaagttcat agatttgaac
    13981 cttatcttca taagtcaatt tcataataaa aacaccccga aagttagatt ttttctgtct
    14041 aacttttggg gtgcagttca taaaaccgtt gctttttgca tgattgtgat agacttggtg
    14101 aaatagaatt gaccaaaaat cttctgaaat ataacaagag agtgactcga atttaaaaag
    14161 ctagagttcc acaattggaa atctctagct tttttgtgac tgagaacttt ttgtcccagc
    14221 ctctactttc tactgactac tatcctgcat gccctaagtc gagatagaga atatctcgct
    14281 tagtggcata ctctagcgca tgttcaacag cctcaaataa atctgaagct agaaaccttt
    14341 tcgtaaagac ggtttcgtct ttacgcttaa atttcgcaac ataactatgt ttagtcattt
    14401 tttctccttc taatattcat attgtccttt aacaccacta tagatccagt aaactgcttt
    14461 atcataaact tgtttaaagg agatacctaa tcgattggct acatcaagaa ttgaaatttg
    14521 cttacattcc tctatattca taaaatatca tcattttgtc gtagtattcg gcaatgatgg
    14581 aacagatgag gattcttcta aagttttagg agttgcctta tctagatcat ctaacccaga
    14641 tttccaaacc tgtacttggt tgaccaataa cttaccaggt agtttcgaat agttcaaatt
    14701 aaccgttctg gtttctgttt ggtttgtctt tgattggttg gcattcttta aatcagatac
    14761 ataagttaca ttataagaga ccatggcaat ggcttgattc gtagtctgat tgacaaagat
    14821 atctgctttt tcaaaatgat aatccaaaat atagtcctta tacacttggt tcatggcatc
    14881 attttgactt gtcaattctt gagaataggc cgattcagtc atataaggtt gaatacgtgt
    14941 attattttcc cctagttttt ctttcgtata gtactgtgtc aaaaattctt ttacagtatc
    15001 tgatgataaa atacttgctt tatcttctgc ttgtttgtcc tctacaagtt tagctgcagc
    15061 caattcgatt tcttttcgac tttgtttggc agtagaatgt tgaccagcag tatatcccat
    15121 catgagaata aagctagttg tggctactgc tccaacacta attaaggctt tagttttgac
    15181 tttatttaac atcttagacc ttctttctat aaaaactagg tcaagcataa cagataaatc
    15241 ttgaaaaaag tatcacaata gaaaaaggac tctgtattga aaaagaatcc ttaatttctt
    15301 ataagccaat caaataattt cttcaaattc ccaaaactca ccactggaaa tacgagccct
    15361 gagtagaata agagcacggt gtttagaaaa tctaccaaga ctgaaatccg ttgaaagcgg
    15421 atagtaagtc gaatcatgac aaagtaatag ccgatgaaaa tcaggaaagc aaccaatacc
    15481 acgagcagtt cctggaaact gatgaccttc aaagaaaagt ggggtagtaa atcctgacga
    15541 atcaacaata gggcaatcca gaagatcaaa gacaaccaaa caaagtaaac cactgctcgt
    15601 tgcaggtaaa ttctatacac tgattgcaaa gcatactggg tgccaaaaga ttgcccagac
    15661 cgaatctcgt actccaactc ttcatttccc aaggaaacca catgggtcaa gatgaaataa
    15721 taatagaaat aggacaactg aaagtcagaa tttcccctca aaaggctata aaaaccaaga
    15781 atgaaaatga cgtggtagag ggtgtcaaac agggtatccg cccagcgtct cctgcgaaag
    15841 agataaaatc gcttcacttc attatacatg gaacaaactt cccttctttt tggcataggt
    15901 caaacaagtt tgaaagcaca agtaacccaa gagccagtaa atcaaaccgt atcccagtaa
    15961 taataaaaga acgaaccaac ttggctggcg gataaaactc accaagagat ggaaaggcaa
    16021 gaaacgagtt aaagtagcaa tcaaatgact cgattgttcc tgaaaaccaa ccaaaaagag
    16081 aatcccgtaa gcaaggaggc tagtaatact ggaaattttt gtaaagacaa aggaaaaact
    16141 ggcaaagaga aagcctagac cataaaggga cgcaataacc acaaaggaca gaagaaaggt
    16201 aacaaatgta acgacccagt cagtaggaaa ggcaatctgc tgaaccaagg caaccaagca
    16261 aaacaatagt aagcatctgt aacattttgt tcatttacac gatactgagt agccacattc
    16321 atcataacaa agacattgtc ctttgttttg gtttcaacca caatctcact ttgaagcaaa
    16381 cgtagttgaa tacgagctgc aattttatcg ataccgaatg gcaaatgcat atgaatacca
    16441 ctcgttgcga ttttttgata gcgtccaaaa cgttcaacga tggctactga ctggctactg
    16501 actgttgacg tacgacataa agcatactga tgagaattcc caagataatc aagaataaaa
    16561 tcagtaaaaa gagaaatgct gcctgcatgt taagtcctcc aaaataaaca ttaaagattt
    16621 ctttgcttta ttatagcaca gtaatacaac tattcaagaa aaatagtata tctttttcaa
    16681 gagctttgac aatcataaaa gaggctgaaa cactagcgtt tcagcctctt gtattttgtg
    16741 actaagctta aaacccaaca gtccaaaagg aaacttttta tttacgatac atcttatctt
    16801 gaaggtaaat gtcattataa atcccaagcc attttttacc taagttatta tagacttcaa
    16861 ggtttttgat ggttgattct gatgggtaaa aggctttatc attagtaata ctctttggaa
    16921 gtaaggtttt agctgcctcg ttaggtgtgg catagccgat atattcagcg ttttgcgctg
    16981 cattttccgg tttaagcatg aagttgataa aagcataagc ttctttttca tgcttcactg
    17041 ttttaggaat gaccagatta tcaaaccaca gatttgagcc ttcagatgga acaacataac
    17101 gaagatcttc atttttatca agcatctcac tggcttcccc tgagaaggtt actccaatag
    17161 ctgcatcacc ttgaatcatg tagcccttca tctcatcacc cacaatagcc ttaatattcg
    17221 gtgtaaggct attaagttta gtttcagcca gacgcaattc cgtcatgttc ttggtattca
    17281 aactgtaacc caagctattg agagaaaaac caatgacttc acgcgcacca tcaaccatca
    17341 taatctggtt tctgtattca ggtgaccaaa gatcattcca gtgctgaggt gcttttttca
    17401 ccaatttcgt attatagaca attccgactg tcccccagaa ataaggaata gaatagtcat
    17461 tattgggatc gaaactaaga cccttaaaac ttgagccaat ctgatcgaag ccatggattt
    17521 tagatttatc caacttcacc aaaaggtctt ccttgaccat cttatcaatg gtgtagtccg
    17581 aaggtacagc gatgtcgtaa gtcgtaccac cttgcttaat tttagtatac atagcttcgt
    17641 tagaatcaaa ggtttcatac tggactttta ttcctgtctc tttagtgaac ttggtcaaga
    17701 gatcagggtc aatgtagtca ccccaattat aaataaccag tttgtccgaa gcacttccgg
    17761 tgcgactttg catgtaggca gaaattcccc aaaggaagaa aataattgct aaaatccctg
    17821 acagaaattg atagagttta cgcatcatgc tcctcctttc tctcctgggt aatcatataa
    17881 tatccaatga ctagaagaat agagaagagg aagacaaccg ttgatagggc attgatttcc
    17941 aaggaaatcc ctttacgagc acgtgagtaa atttccacag caagtgttga aaaaccatta
    18001 cccgttacaa agaaggttac tgcgaagtca tccaaagaat aggtaaaggc catgaaataa
    18061 ccagcgataa taccaggtgt caagtatggc aacatgacct cgcgtaacat ctgccattgg
    18121 gtcgcaccca ggtcataagc tgcattcacc atgtctcgat tcatttcctt gaggcgcggc
    18181 aaaaccatga gaaccacgat tgggattgag aaggcaatgt gactcaacaa aaccgataca
    18241 aagccaagtt ggaaaccaat ccaggtaaag agaatcaaga aactcgcacc aatcataacg
    18301 tccggtgcaa ccattagcac gttatttagg gataagattc cagtctgctg cttctgcttg
    18361 ctctcataga taaaaattga cccaaaggta ccaataatcg tcgccaagag ggcactaaga
    18421 aaagctaaaa agaaggtttg agctaaaatc aacatgagtc gactatctga aaacatgctc
    18481 tgatagttat caagagtaaa tcctgtgaaa ctattcatat cgccaccact attgaaagaa
    18541 aaggcgatta gataaaagat tggcaggtag atgataacaa agactagagc taaatagaga
    18601 tttgcaaatt ttttcattga cgtctctcct ttgttaacca catgattgca atcatagtaa
    18661 caataagcac aacaccaatg gtcgcaccca ttccccagtt ttgtgttgtg aggaaatgct
    18721 gttcgatagc cgttcctagt gtaataactc ggttcccacc aatcaaacgt gttagcatga
    18781 agaggctaag actaggaatg aagaccgatt gtacacccga gcgtacccca ttaagcgaca
    18841 aaggaaagat aatcttggta aaggtctgcc aatcattagc tcctaaatcc ttacttgcat
    18901 tgacaatatt ttcatccaaa tcatccagag cattaaaaat cggtagaatc ataaatggaa
    18961 tttcaatata actggctaca aaaatgaaag aaaaatctgt aaagagaatt tgcatgggag
    19021 caatcccaaa gaaaccaaga aaggcgttaa ttccaccttg ttggccaaaa atccccataa
    19081 aggcataagc ttttagaaga aggttgaccc aggttggtaa aataactaac atcaaccaaa
    19141 gttgtttatg cttcagtctg gttaggagat atgcggtcgg ataagagatg aggagtgtca
    19201 ctaaggttat gatggccgca taaaggaccg agttaaagct catcctcaag taagtccaac
    19261 tggaaaagaa ggttccatag ttgtccaaag taaaattgcc actgatgtca aaaaatgact
    19321 ggtagagcag catgagtact ggagcaacta cgaaaagtag aagccaaaga aggtatggta
    19381 ccgagaagag gctagctgtt ttcttcatga cgctcctcct caatggcatt aatcaagcca
    19441 tcctcaggct cttccatttc cacatattct tcaatacgag catcgaattc ttcctctgtc
    19501 tcattaagac gcatgatatg aatatcttca ggcgtaaaat caaggccaat aatctcaccc
    19561 tcaatcgcct tacgggttga atgaatcatc cattcattgc caagattatc ataggcaatg
    19621 atttcatagt ggaccccacg gaaaagctgt gtttctacac gaacctgaag cttaccttcc
    19681 tcaggaagcg tgatttgtaa atcttcagga cggataacca cttcgacagg ttcatttgga
    19741 cgcattcctc catcaacaga ttcgaaacgt tttccgttga actcgaccaa atagtcctca
    19801 atcatgactc ctggtaggat attagattct ccgataaagg ttgcaacgaa atggttgata
    19861 ggctcgtcat agatatcaac aggcgttcct gattgaacaa tttcaccatc gttcataaca
    19921 aaaatccagt ctgacatggc caaggcttct tcctggtcgt gggtgacaaa gacaaaagta
    19981 atccctagac gtttctgtag ttcacgcaac tcgtattgca tttcagtacg taacttcaaa
    20041 tccagtgctg acaagggctc atccaaaagg accacacgtg gctgattgat aatcgcacgg
    20101 gcaatagcta cacgttggcg ttgaccaccc gataattttt gaatcgagcg cttttgataa
    20161 ccatctagtt gaaccatttt caatgcttct tttacacgct cttcaatttc cttcttaggc
    20221 acttttttta acttaagcgc aaaagccaca ttgtcaaaga cattcatgtg tggaaagagg
    20281 gcataagatt ggaaaacggt gtgaacatcc cttttattga tagggatatc attaatacgc
    20341 tttccatcca aaagaacgtc accactggtc gcatctaaga gaccagcaat gatgttcaag
    20401 atagttgatt taccagaacc agaagcccca agcagggtat agaacttacc ttcttccagt
    20461 tcaaagttga tgtcttttaa aacttgtgtg ccactgtctt caaatacttt cgagacgttt
    20521 tgaaaggcaa taatcggatt agtcaattgt cataaatcct ccatggatat caaaaatagg
    20581 gttagtatta ttaatttaat ttgtcgccaa tgatgcgaac ttcaggctct agtgtaacac
    20641 ccgaattttc cttaacctta gcgataacat ctgcaataag atcttcatag tctttcgctg
    20701 ttccttgatc gacattgacc atgaaaccag cgtgcttggt tgaaacctca acaccaccga
    20761 tacgatgtcc cttgaggtta gcttccataa taagctgacc agcaaaatga cctggcggac
    20821 gtttgaagac cgaaccacat gatgggtatt cgagaggttg tttaagttct cgtaagtgat
    20881 taaggcggtt catctcatgt ttgatttgtt cgtagtctcc tggtttgagg ttaaattttg
    20941 ctgaaataat cacttcacct gtttcttgga gcaccgaacg acgataacca aaacgcatat
    21001 ctcttgcatc aatcgtacga atatcaccat cttttgtaag aacctgagca gaaaccaaga
    21061 tatgtgcaat ctcgccacca taggcacccg cattcataaa gacagcacca ccaatactac
    21121 ctggaattcc cgccgcaaat tcaaaaccgg tcaaactatg gaaacaagcc accttggttg
    21181 ttgcaatcaa attagctccc gcttctgctt caacttgata accattgaca gcgataccat
    21241 taagcttgtc aaacataatc acaaaacctc ggataccacc gtcacgaaca atcaaattac
    21301 tggcattacc aagcaccatc catggaatgt tgtgcttgtt ggcaaatttg acaatacgag
    21361 aaagctcata tcggttacgt ggaaaggcca aataatccgc tggacctcca accttggtgt
    21421 aagtataacg ttttaagggt tcgtcgaaac gaatatcaat cccaactaaa tcttctttaa
    21481 gttcatctaa catgttaatt cccatacttt ttctatacat ttatttcttt gtaggtattg
    21541 tgaaaaattt ccccttatta ctatcacaac ctaaaaatga gttagtattt tccctaacaa
    21601 ttaaaagaaa aataccacaa aaagccaaaa ttaattatag caaaaaatcc ctatcttgac
    21661 gacaaggaat tttagtaaaa actagtccac ttgctccaat ttgcggacat cactagtgtc
    21721 tatttgactc aaatattttt tgtaggcttg accagtttga ggctcaacta aattctcggc
    21781 aatttctagc agaggaacca aaacaaaggc cctttgagtc atgagaggat gaggcacttt
    21841 aaggtgctca gtcccccaga tttcctgccc atataaaaga atatcaatat ccacagttcg
    21901 agggccccaa tgctcatggc gaacgcggtc taaatctttc tcaattgcct gacaagcact
    21961 cagcaagctt tcagccggca actgagtgtc aagtgctaaa gcgagattca aaaaatcagc
    22021 ctggtcagtt aatccccaag cagccgtctc ataataagag gacactgctt taacttccgt
    22081 ctcaagcaag cgatccaatg actccaccgc ttttttaaga tagtcttgac gatttcccat
    22141 attagatccc aaacttaaat aaacttttgt catcgactac gctccaattc aattccaaca
    22201 cttctatagt gcccattaat tggtggattt tctttaataa ttcgaatttt aatagattgg
    22261 attggcacaa attgatcaaa caagtcctca caaatagcac cagctaaacg ctcaatcaaa
    22321 atatactttt cttcttccac ctgtctctgt acggcttcaa aaactaaacc ataatgaacc
    22381 gtatctgcta gattgtcact ttgtgaagcc ctggtcaaat caaca
//
