LOCUS       c00003_JAIEWK0..       13532 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIEWK010000003.1 Alkalihalobacillus clausii strain ZBGE1
            contig_0000003, whole genome shotgun sequence.
ACCESSION   JAIEWK010000003
VERSION     JAIEWK010000003
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 05:09:03
            Original ID  :: JAIEWK010000003.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 373384
            Orig. end    :: 386916
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13532
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[378384:381916]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8532
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
     cand_cluster    1..13532
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13532
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     CDS             25..777
                     /locus_tag="ctg3_396"
                     /transl_table=11
                     /translation="MLLLYQLLVWLTVLGLGLYVFASWRWEEETKKRLPIIRRLWYAWF
                     VTGAAFTWTFYPESIFTEWNHYLIVALLFVVVDAFVFLSAYVQRIGSNVFTIDTGQLIE
                     ANDQVLKAQQDRLKAFFRLLKSDSINVYYGGQRAYITGVREILARLADKTEIQASVFPF
                     MTQGDKDHLLVHFKDRTTVRATLERQDVYYGEKDKLVFIPVILQGESHVIKLSSEERLT
                     EFDALLFASLVAIYDLLSQGGDEEQYEE"
     CDS             1110..2114
                     /gene_functions="other (smcogs) SMCOG1251:luciferase family
                     protein (Score: 109; E-value: 4.8e-33)"
                     /gene_kind="other"
                     /locus_tag="ctg3_397"
                     /transl_table=11
                     /translation="VIKLSVLDQVPRSSETTNEIALKETADLAQAAESMGYFRYWVAEH
                     HDLHGLLSPSPEILLAYIGAKTNSIRLGAGAILLPHYAPFKVAESFHMLANLFPGRIDL
                     GLGRSPGGSAEAAEALSGNFIERIHTMDERMTELMHFLKRDFPEGHKYASLQAVPLPYE
                     QPAVYMLGTSKKSAALAAKHNLQYVYGHFMDDQNGQDVIAHYRKRANQATKPIVCVFVL
                     CAESNEKARQLYRSVRLWQTANQQGRMMAAIPTEAETAYFLTQLNEEDRAAVMNVPSTA
                     IVGDKQHVKERLDAIANSLHVDELMVLTHAPELSDRLHSYRLLAEIYPQLVSL"
     CDS             2234..3160
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 333; E-value:
                     2.4e-101)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_398"
                     /transl_table=11
                     /translation="MEVYRHIHELIGSTPMLELTAFPLPRRVRLFAKLEYTNPGGSIKD
                     RLGIKLLKEAIATGKITPKGTLIEPTAGNTGIALALAAIGTDVKVICVVPKAFSIEKQQ
                     LMRALGAVIVHTPSEHGMKGAIAKAKALEQELDDAYCPQQFSNKANPLAYYETLGPEIV
                     HELDGKVDVFVAGAGTGGTFSGTAAYLKEVIPGIRTVVVEPEGSILNGGEPGPHRTEGI
                     GMEFIPDFVNRSLFEAIYTISDNQAFKRTRELAEHQGVLVGSSSGAALEAALREAEMAD
                     EGARIVTVFPDGAERYLSKGIYEEEPL"
     CDS             3157..4293
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168:O-succinylhomoserine sulfhydrylase (Score: 414.7;
                     E-value: 4.9e-126)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_399"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.4e-08,
                     bitscore: 28.4, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRKKTQLIHGGIGMDAETGAVTPPIHPASTFKQKGIGNFQYEYGR
                     TGNPTRHALESLLADIESGTHGFAFASGLAAITAVMKLFSSGDHIIVTDDVYGGTYRLF
                     TKILQREGIAATFVDTEDQAAVARARTSKTKAIFIETPTNPLLKVTDIRKLASYAQAEE
                     LLLIVDNTFATPYWQNPLVLGADIVVHSATKYLGGHSDVVAGAVVVKDEKLAETLAFIQ
                     NATGAVLGPTDSWLLMRGIKTLGVRMEEIETNARMLVKFLLGHPNVSRIYYPGLVEHPG
                     HATHALQARGFGGIISFEAASEEIADNVLNKTTYFTLAESLGAVESLISLPAKMTHASI
                     PEDRRSALGITNTLVRLSVGLEDFEDLAEDLEIGLTVF"
     CDS             4535..4876
                     /locus_tag="ctg3_400"
                     /transl_table=11
                     /translation="MFFLQTKTLIVEEGHGDKMVAKFAADGIIEEQPGFIDLQVMKQKP
                     RKGQEEILVLIRWDSEESWKAWEKSDAHLAGHRANRGKPKPSFIIDSNQKVYNHLAGKS
                     SRKPVKHES"
     CDS             5001..6818
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_401"
                     /sec_met_domain="IucA_IucC (E-value: 2.5e-64, bitscore:
                     212.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPSTKHIAESASFQAFVNGFIRETGAGCIKALTTVDEVELQQKM
                     HGPFIMELHLPLQKTTLWIDVPYRSLVGRHTFGDVFRIKQGGKWQQEEPFSAMILLVQE
                     LHAQAKSNPEKRSSCFEECLLRMIDSLQTMHSYIEVRQKDGEKLYESKQCFIDSEQSLL
                     YGHWFHPTPKSRQGMAYWQHSLYAPELKGRFQLHYFLVHHDLVEHGSLLESSACELVAQ
                     DVGAPSFRNNDQNWIVFPMHPLQAQYLLKHTSVIKAMEQGLIKDIGPAGKLFSATSSIR
                     TVTSESGKWMYKFSIPVKVTNSLRLNRRHELQAGMLVATLLHHSETLRINKGFHMIGDP
                     AYMTVRLPGMEESGFETIIRENPFQDGGAGVTSIAALTQDPLPGYDSKLAGLMKKVAVR
                     ECLPVSTVSIHWFKHYIDVAVRPLIHLYDELGLALEAHQQNSLINIYSGYPSAFYYRDN
                     QGYYLANSYKDALLAKEPKLKDVDGLFYKDALIDDRFAYYLILNQVFSLICRFGVDGLQ
                     EEAVLLEVLRSALAELEVTLVGAGKRFVQGLLGNEQLACKANLLTRFHDVDELAEELEQ
                     AVYTSIKNPFKSTGKKEGVAYAHAGSAIF"
     CDS             6790..8532
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_402"
                     /sec_met_domain="IucA_IucC (E-value: 5.5e-75, bitscore:
                     247.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHMQAAPYSKAALRVRRQLMEAILFEKLLDVEETNKSNGDTVFTV
                     YGRSCLFQCIGKRSAFGRIRLRQGPYRLIGERQVRLARIEEIVNELTAEETRKQALIEE
                     LFQTIKLSDWNETKLRKTVSRRGLAYEQLEAALIEGHPYHPCFKARKGFSFDDHDRYGP
                     EAQQSFHLVWLGVRKQDAIVHYPQEAGSFLQQELGAPVWQALVKALSEAGGQLSEYEFV
                     PVHPWQWQALNEHLLQQAIKRGDVLYLGQFGDAYCATQSLRTVMNVEHGTKAQLKLPLN
                     VVNTSSVRTIPPHLIAAAPAISVWLQRIIDSDPFLKDEIGVERLAEYAGVAYEPKGKQW
                     NKAILGQIGCIWRESVPSKLRPGEQAIPMNALPLIEEDGALFIAPFIERFGIEAWLMQL
                     FRISVIPVIHFLAEHGIALEAHGQNVILVTEKGWPKRVILRDFHESIEYKESFVKERAW
                     IPHFSTLHQAFQSGKTDEYYWMSSLEALRELVMDTVFVYQLTELSWQLEQHFHFSEQQF
                     WSLVDCVIRDYAARELVPPERLQALRLAAPVIATESLLTSKVTGKENCRHLVNNELGRE
                     SRTC"
     CDS             8526..9764
                     /NRPS_PKS="Domain: AMP-binding (31-272). E-value: 8.3e-22.
                     Score: 69.0. Matches aSDomain:
                     nrpspksdomains_ctg3_403_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     101.3; E-value: 7.4e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_403"
                     /sec_met_domain="AMP-binding (E-value: 7.1e-18, bitscore:
                     59.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTVNDCTYTKDDLKRCEQQFAMHSIWKTAEQWRIAVCPQEIEKW
                     IALLLYVKKRGGSIVPIHPSTPLAAAKKIAVQARCAYLFFHTFETPLTLSNPVSTFPPG
                     LVQFSSGTTGVPKQLERSWSSIDEELAAYTERMARVDVDTVVVACPVTHSYGLISGVLA
                     GLSQDKEVVVLTAQNPKYVLKKLTDYPNHLLYGAPPLLYALAKLSNGDTLQAVMTSGTR
                     LPEEWFQSIQSNSQMLLQQYGCSEAGCISIAMPLRFSEELGVPLRHVQAKAGTARNNPS
                     EIQVTIGRRTINTGDLGYIDQDGALCFRERLDDMINVAGLNVYPHEVEHVLREHPSVED
                     AVVYKKADSYAGERVCAQVSARTETLSLHELRSYCISRLAPHQVPHEMTIVEEIAKSAN
                     GKVSRVKLGEAKG"
     aSDomain        8619..9341
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg3_403_AMP-binding.1"
                     /evalue="8.30E-22"
                     /label="ctg3_403_AMP-binding.1"
                     /locus_tag="ctg3_403"
                     /protein_end="272"
                     /protein_start="31"
                     /score="69.0"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="QWRIAVCPQEIEKWIALLLYVKKRGGSIVPIHPSTPLAAAKKIAV
                     QARCAYLFFHTFETPLTLSNPVSTFPPGLVQFSSGTTGVPKQLERSWSSIDEELAAYTE
                     RMARVDVDTVVVACPVTHSYGLISGVLAGLSQDKEVVVLTAQNPKYVLKKLTDYPNHLL
                     YGAPPLLYALAKLSNGDTLQAVMTSGTRLPEEWFQSIQSNSQMLLQQYGCSEAGCISIA
                     MPLRFSEELGVPLRHVQAK"
     aSModule        8619..9341
                     /domains="nrpspksdomains_ctg3_403_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg3_403"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9375..9413
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_403_0001"
                     /evalue="4.30E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg3_403"
                     /protein_end="296"
                     /protein_start="283"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="QVTIGRRTINTGD"
     CDS_motif       9453..9512
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_403_0002"
                     /evalue="4.30E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg3_403"
                     /protein_end="329"
                     /protein_start="309"
                     /score="13.1"
                     /tool="antismash"
                     /translation="ERLDDMINVAGLNVYPHEVE"
     CDS             9761..10027
                     /NRPS_PKS="Domain: PP-binding (8-78). E-value: 8.6e-12.
                     Score: 37.2. Matches aSDomain:
                     nrpspksdomains_ctg3_404_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_404"
                     /sec_met_domain="PP-binding (E-value: 8e-11, bitscore:
                     37.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKKEAMDAIYTILEHELKLPTLEQFHQDARMNEDLALDSIMILQ
                     LLLELEMKYGVAIPDEHIDIKAFYTVGALAAFVADKQEDPLYD"
     aSDomain        9785..9994
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg3_404_PP-binding.1"
                     /evalue="8.60E-12"
                     /label="ctg3_404_PP-binding.1"
                     /locus_tag="ctg3_404"
                     /protein_end="78"
                     /protein_start="8"
                     /score="37.2"
                     /tool="antismash"
                     /translation="AIYTILEHELKLPTLEQFHQDARMNEDLALDSIMILQLLLELEMK
                     YGVAIPDEHIDIKAFYTVGALAAFV"
     aSModule        9785..9994
                     /domains="nrpspksdomains_ctg3_404_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg3_404"
                     /tool="antismash"
                     /type="unknown"
     CDS             10020..10994
                     /locus_tag="ctg3_405"
                     /transl_table=11
                     /translation="MIKVHCFVSCICEVLKKRGIDHRPYYFGVWDADFAIDDSYALAYH
                     SETIDHSFLKNWYRHLYGIDMHEWYKKEQTKEANIAKLETLLETRPSFRNVMVMLDLAL
                     LPERENKFHQKPFPHYVLLEKTGTESQWLMLDPDYRWEGVIEKERILEAIRSPDVGGGF
                     YFDAKQIHQPTPETVEAYFQTCMKLHSNPLTEGVRTIVEAYVNGSEKARCSALAVALKQ
                     LPVLAIRKYAYEHAFAYFWKELGFKEAEFEEWCDEIEKLAKGYTTIHYRAMKLSRTKHE
                     RDYQAVLAQLEKQDLRERRIKHRLYDYFRGWKQLQEMARGVNA"
     CDS             10991..11821
                     /locus_tag="ctg3_406"
                     /transl_table=11
                     /translation="MNVSICTISFRHALVSIEQLADWAKAHDVDGIELWAPHARHLFAT
                     PSYNGDWLKKQGLIVPMVSDYFPLYEEWNTLIEAAKQASRLLTRWNTNHIRTFAGAKGS
                     KDTTKAERAYLVKRLACLCDYFFDKGHYVLVETHPHTLCDTVPSTLQLLAEVDHPGLAI
                     NFDVLHVWESGADVNDAFKQLQPHIRHLHVKNIRSPEDLDVFAPENVYAAAGSREGMAG
                     LFNGSVDYESFLSANQLDGVNVSIEWFGNDPFHVLEQDCKQLMKWKTVPNRVGH"
     CDS             complement(11832..12395)
                     /locus_tag="ctg3_407"
                     /transl_table=11
                     /translation="MKGRINLKQAVFLDRDGVINEVLSKRVKFVNDANDFHLLDGVAEA
                     IRFFNKAGFLVFVVTNQGGIGLGYMKEKKLELIHKKMEADLKAQGATIDDIAYCPHKPN
                     EGCPCRKPKAYLLKKLADKHYVDLPASVMVGDREPDIRAGQKAGCQTVLVHARTEDDFQ
                     ADARFPDLRAAVPWIIAQKRAAAR"
ORIGIN
        1 catgcaaaaa tagggggtga gcacatgctt ctgctgtacc aattgcttgt gtggttgacc
       61 gtattagggc tggggctata tgtatttgcg tcttggcggt gggaagagga gacgaaaaaa
      121 cggctcccga tcatacgaag attatggtat gcatggtttg tcactggagc agcatttaca
      181 tggacgtttt acccggaaag tatttttact gaatggaatc actatctgat tgttgctttg
      241 cttttcgttg ttgtcgatgc ctttgtgttt ttgagcgcgt acgtgcaacg aattggttcc
      301 aatgtgttta caatcgatac cggccaactg attgaagcaa acgaccaagt gctcaaagcg
      361 cagcaagaca ggctaaaagc tttttttcgt ttactaaaaa gtgactcgat taacgtctat
      421 tacggagggc agcgtgcata tattaccggt gtgagagaaa ttctagcaag gttggccgac
      481 aagacggaaa tccaagcaag cgtctttcct ttcatgacac aaggcgataa agatcatttg
      541 cttgtgcatt tcaaagaccg cacgacggta agagcgacac tggaaagaca ggatgtttac
      601 tacggagaaa aagataaact tgttttcatt cctgtgattt tacaagggga gagccatgtc
      661 attaaactgt cttctgaaga gcggcttacc gaattcgatg cactcttgtt tgcctcactt
      721 gtggccattt atgatcttct gtctcaaggc ggggatgaag agcagtatga agaatgattg
      781 ggaaaaaata ggcatagcca ttctcaccga tgaaagcatg caggaatagt ctatcttata
      841 atgagttgag tgggtgaagg gttgatgaag aagacgacaa agaaatcaac taacagcgtg
      901 cttcctgggt ttgctacctc tccgtacacg gctgatttgc aaaaaaagaa caaagaagcg
      961 attcagctat ttaagaaatg gaaatcggac aaaaaacgga aagcgcgcta ggcagaatgg
     1021 gatcgtccat tctgcttttt tgtgtttaag ttgccaatcc ctacaaaatt cgatacggta
     1081 aaggaagact aaatgaaaga aggattcttg tgataaaact tagtgtccta gaccaagttc
     1141 ctcgctccag tgagacaaca aatgaaattg ccttaaagga aacagccgac ttggctcaag
     1201 cagctgaaag catgggctat ttccgttact gggtggccga acaccacgat ttgcatggct
     1261 tgctttcgcc aagccccgaa attttactag cctacatcgg tgctaaaacc aactcaatcc
     1321 gcttaggggc tggagcaatc ttgcttcctc attatgcccc ttttaaagtg gcagagtctt
     1381 ttcacatgct tgccaacctt tttccagggc ggatcgacct tggcttgggc cgttcgccag
     1441 ggggttcggc agaggctgcg gaagcccttt ctggcaactt tatcgaacgc attcatacga
     1501 tggacgagcg tatgacggag ctcatgcact ttctgaaacg tgactttcca gaagggcata
     1561 aatacgcttc cttacaagct gtgcctcttc cttatgaaca gccggcggtg tatatgcttg
     1621 gaacgtctaa gaagagcgct gccttagcgg ctaaacataa cctccagtat gtttatggcc
     1681 attttatgga tgatcaaaac ggccaagatg tcattgccca ctatcggaag cgtgcgaatc
     1741 aggctacgaa gccaattgtt tgtgtgtttg ttttatgcgc cgaatcgaac gaaaaagcga
     1801 ggcagcttta ccgctctgtg cggctgtggc aaacagccaa tcaacaaggg aggatgatgg
     1861 ccgcgatccc gactgaagcg gaaacggctt attttctcac ccaattgaac gaagaagacc
     1921 gtgctgctgt aatgaatgtg ccatcaaccg ccattgtggg cgacaaacag catgtgaaag
     1981 aacgcctgga tgccattgct aattcgcttc atgtcgatga gttgatggtg ttgacgcatg
     2041 cgcctgagct tagcgatcgc cttcattcat accggctatt ggctgaaatt tacccacaac
     2101 ttgtttcctt ataggccccc tataagcgct gcccatgtgt cctggcggcg ctttttctct
     2161 tcttcaaaag taggcaccaa tccaaatttg cgacatacgt tgaaataaac ggcattgcaa
     2221 atgaggtggt tagatggaag tgtaccgcca tatccatgaa ctcataggtt caacccccat
     2281 gcttgaactg acggcctttc cgctcccgcg ccgtgtgcgt ttatttgcaa agttggagta
     2341 taccaatcct ggaggaagca ttaaagaccg tttaggcatc aaactcctca aggaagcaat
     2401 tgccaccggt aaaatcacac cgaagggcac attgattgag ccaacggctg gaaatacagg
     2461 gattgctctt gcgctcgcag cgattggcac ggatgtaaag gtcatttgtg tcgtgccaaa
     2521 ggcatttagc atcgaaaagc agcagctgat gcgcgccctt ggagctgtca ttgtccatac
     2581 accgagtgaa catgggatga agggagcaat tgcaaaagca aaagcgttag aacaagagct
     2641 tgatgatgct tattgcccgc agcagttcag caataaagcg aatccactcg cttattatga
     2701 gacgcttggc ccagaaatcg ttcacgagct tgatggcaaa gttgatgttt ttgttgcagg
     2761 cgctggaaca ggagggacgt tttcaggaac agccgcttat ttaaaagaag tgatccctgg
     2821 cattcgcact gttgtggtgg aaccagaggg ttcgatttta aatggtgggg agccaggacc
     2881 gcaccggact gagggaattg ggatggaatt catcccagac tttgtaaaca ggtctttatt
     2941 tgaagccatt tatacgattt cagacaacca agcgtttaag cggacacgcg aactcgctga
     3001 acatcaaggt gtgcttgtcg gcagttcttc aggtgctgct cttgaagctg ccttgcgaga
     3061 ggctgaaatg gccgacgaag gtgcccgtat cgtcactgtc tttcctgacg gggcggaacg
     3121 gtatttgagc aaaggcattt atgaggagga acctttgtga ggaaaaagac acagcttatc
     3181 catggtggca ttggaatgga tgctgaaaca ggcgcagtca cgccaccgat ccatccagcc
     3241 agcacattta aacaaaaagg aattggcaac tttcaatatg agtatgggcg aacgggcaac
     3301 ccgacgcgcc atgcgcttga gtctttgctt gctgatatag aaagtgggac ccatgggttt
     3361 gcctttgcct caggattggc tgcgatcacc gcagtgatga agcttttttc atctggtgat
     3421 catatcattg taaccgacga tgtgtatggc gggacatacc ggctatttac aaagattttg
     3481 caaagggaag ggattgcagc tacttttgtc gatacggagg atcaagcggc tgtcgcaagg
     3541 gcaagaacaa gcaaaacgaa agcgattttt attgaaacgc caacaaatcc attgctgaaa
     3601 gtaacggata tacggaaact ggccagctat gcgcaagcgg aagaattgct tcttattgtt
     3661 gataatacgt ttgccacccc ttattggcaa aaccctcttg tattaggagc ggatatcgtc
     3721 gtccatagcg ctacaaaata tttaggcggc catagtgacg ttgttgctgg cgcggtagtc
     3781 gttaaagacg aaaaactagc tgaaacgctc gcttttattc aaaatgcgac aggcgctgtt
     3841 cttggcccga ctgacagttg gctattgatg cggggcatca aaacgctcgg tgtaagaatg
     3901 gaagaaattg aaacgaatgc gcgtatgctc gtgaaatttt tgcttggcca tccaaatgtc
     3961 agccggattt actatccagg tttagttgaa catcctggcc atgcaacgca tgctttgcaa
     4021 gcgagagggt ttggcggcat tatttctttt gaggctgcga gtgaagaaat tgctgacaat
     4081 gtgttaaaca aaacgaccta ttttacttta gcagagagtc tcggagcagt tgaaagcctg
     4141 atttcattgc cagctaaaat gactcatgcc tcgatcccag aagacaggcg cagtgccctt
     4201 ggcattacaa atacactcgt tcgtttgtct gttggtttag aagactttga ggacctggcc
     4261 gaagatttgg aaatagggct tacagtgttt taaacacgtg cgatacgcgc gtgttttttt
     4321 atgtaactag gacgtttgtc gcgttttgag gaagcaaaaa tgagaggata agaacgacaa
     4381 tgtgtgtttt tcaggttaat cgtggaaaac aaaaggctag tgttcgtcat cggagtcgct
     4441 ctgctatgag caaatggaag caatttcaaa aaagaagttg aaaatgagaa tcgttatcaa
     4501 tataatgaga atagagaaga cgaggaggga ttgaatgttt tttttgcaaa cgaaaacgct
     4561 cattgtcgaa gaaggacatg gagacaagat ggtcgcaaaa ttcgctgctg acggaatcat
     4621 tgaagagcag ccagggttta ttgatttaca agtaatgaaa caaaaaccac gaaaaggcca
     4681 agaagagatt ttggtgctga ttcgctggga ttcagaagag tcgtggaagg cttgggaaaa
     4741 aagtgatgcc catctggctg gccatcgtgc caatcgtggc aagcctaaac cttcatttat
     4801 cattgattcc aaccaaaaag tatacaacca cttagctggc aaatcgtctc gcaaacctgt
     4861 taaacacgaa agctaatgga ctattggaac gttaaaaaga gacgcgatga aacggtgttg
     4921 tacaagtata acggggcaac ccgttttttt aaaacataat tgagaataaa tctcattaga
     4981 tttccagaag ggatgaaaac atggctccat caacgaaaca tattgccgaa agtgcgtcat
     5041 ttcaagcatt tgtaaacggc tttattcgtg agacgggggc agggtgcata aaggcattaa
     5101 caaccgtcga tgaagtcgaa ttacaacaaa agatgcacgg ccctttcatc atggaactgc
     5161 atttgccact acagaaaact acgttatgga tcgatgtgcc ttacaggtcc cttgtcggcc
     5221 gccacacgtt tggggatgtt tttcgaatta agcaaggagg aaagtggcag caagaagagc
     5281 ctttttcagc catgattttg cttgtacaag agttgcatgc acaagcgaaa tcaaatccgg
     5341 aaaagcgaag ctcttgtttt gaagaatgct tgttgcgcat gatcgatagt cttcaaacga
     5401 tgcactccta tatcgaagta cgtcaaaaag acggggaaaa actatacgaa agtaaacaat
     5461 gttttattga ttcggaacag tcgctcttgt atggccattg gttccatcca acaccgaaaa
     5521 gtaggcaggg tatggcttat tggcaacatt cattatatgc accggagtta aaaggacggt
     5581 ttcagctcca ttattttctt gtccaccatg accttgttga acacggctcg ttgcttgaga
     5641 gcagcgcctg tgaattggtg gcacaagacg ttggcgctcc gtcatttcga aataacgatc
     5701 aaaattggat tgtctttccg atgcatccgc tccaagccca atacttgcta aagcacactt
     5761 ctgttataaa ggcaatggaa caagggttga taaaagacat aggaccagcg gggaagcttt
     5821 ttagcgcaac ctcttcgata cgaacggtta caagtgaatc aggaaaatgg atgtataagt
     5881 tttcgattcc agtaaaagtc accaattcac tccgattgaa ccggcgtcat gaacttcaag
     5941 caggaatgtt ggtagcaacg ttgctccacc actcggagac gctccggata aataaggggt
     6001 ttcacatgat cggggatcca gcttatatga cggtacgttt gcctggaatg gaagaaagcg
     6061 ggtttgaaac gatcattcgt gaaaatccgt ttcaagatgg cggtgccggc gtcacttcta
     6121 ttgctgctct tacccaagat ccattgcctg gctatgattc aaagcttgcg ggcttaatga
     6181 aaaaggtcgc ggtgcgcgaa tgcctaccag tctccacagt tagcattcat tggtttaaac
     6241 actatattga cgtggctgtt cggccactta tccatttgta cgacgaactt ggtttggcac
     6301 ttgaagcaca tcaacaaaat agcctaatca acatttatag cggctacccg agcgcttttt
     6361 attaccgtga caatcaaggc tattacttgg caaattctta taaagacgct ctgttggcaa
     6421 aagagcctaa attaaaggac gtcgatggac tattttacaa ggacgccctc attgacgacc
     6481 gatttgcgta ctatttgatc ttgaaccaag tgttttcatt aatctgccgt tttggtgttg
     6541 acggtctcca ggaagaagcg gttttgcttg aagtgttgcg ttcagcgctc gctgaactgg
     6601 aggttacttt agttggagca ggcaagcgtt ttgtacaagg gttactggga aacgaacagc
     6661 ttgcttgcaa agcaaattta ctaacgcgct tccacgatgt cgatgaacta gccgaagagt
     6721 tagaacaagc ggtctatacg tcaatcaaaa acccgtttaa aagcacgggt aaaaaagaag
     6781 gtgtcgccta tgcacatgca ggcagcgcca tattctaagg cagcgttgcg ggtacgacgt
     6841 caattgatgg aagcgatcct atttgaaaag ttgctggacg tcgaggaaac gaataaaagc
     6901 aatggggata cggtatttac cgtgtacggt cgttcgtgtt tgttccaatg cataggaaag
     6961 cggtctgctt ttgggcggat tcgtttgcgg caaggaccgt accgactcat aggcgaacgc
     7021 caagtgcggc tggcgagaat agaggaaatc gtcaatgaac tgactgccga agaaacgaga
     7081 aaacaagcgc tgatagaaga acttttccaa acgataaagc taagtgattg gaatgaaacg
     7141 aagcttagaa agacagtatc gagaagggga ttggcttatg aacaattgga agcagcgcta
     7201 atcgaaggcc atccttacca tccttgtttt aaagcacgaa aagggttttc gtttgacgat
     7261 catgatcgtt atgggcccga agctcaacaa tcatttcacc ttgtctggct tggcgttcgc
     7321 aagcaagacg cgattgtcca ttatcctcag gaagcaggtt cctttttgca gcaggaatta
     7381 ggcgctcccg tctggcaagc gctcgtaaaa gcattatctg aagcgggcgg ccaacttagt
     7441 gaatacgagt tcgtccctgt tcatccgtgg caatggcaag cgcttaatga acatttgctc
     7501 caacaagcga tcaaaagggg agacgtgttg tacttaggcc aatttggcga cgcatactgt
     7561 gcgactcaat ctttaagaac agtcatgaat gtcgagcatg gaacgaaagc gcaattaaaa
     7621 ttgccgttaa atgtcgtcaa tacctcttcg gttcgtacaa tcccgcctca tttgattgca
     7681 gcggctccag ctatttccgt gtggttacaa cgcatcattg acagtgaccc gtttttaaaa
     7741 gacgaaatcg gcgttgagcg cctagcagag tatgccgggg tggcgtacga acctaaaggc
     7801 aaacaatgga acaaagcgat ccttggccag atcggttgta tttggcgcga aagcgttccc
     7861 tccaaactga ggccagggga gcaggcgatt ccaatgaacg ctttaccact gatagaagaa
     7921 gacggcgcgt tgtttatcgc cccttttata gagcggtttg ggatagaggc gtggcttatg
     7981 cagttattca gaataagcgt aatccctgta atccatttcc tagctgagca tggaatcgct
     8041 ctcgaagcac atgggcaaaa tgtcattctt gtaactgaaa aagggtggcc aaaacgcgtg
     8101 attttgcgtg actttcatga aagtatcgaa tacaaagaga gttttgtgaa agaacgtgct
     8161 tggatcccgc acttttccac attgcatcaa gcatttcaat cagggaaaac cgacgagtat
     8221 tattggatgt cttcccttga agcactaagg gaactagtga tggatactgt ttttgtttat
     8281 cagctcacag aactatcgtg gcaactggaa caacattttc actttagcga gcagcaattt
     8341 tggtcattgg tcgattgcgt catccgtgat tacgctgcca gggaactcgt accgccagag
     8401 cgtttgcaag ctttacggtt agctgctcct gttatcgcta cagagtcact gctaacgagc
     8461 aaggtgacag ggaaggagaa ctgtcgccat ttggtcaaca atgaacttgg gagggaaagc
     8521 cgtacatgtt aactgtaaac gattgcacct atacaaaaga tgatttgaag cggtgcgaac
     8581 aacagtttgc tatgcactcc atctggaaaa cagctgaaca atggcggatt gctgtctgcc
     8641 cacaagaaat tgaaaaatgg attgcactcc tgttatacgt caaaaaaaga ggcggcagta
     8701 tagtaccgat ccatccaagt acgcctcttg ctgcagcgaa gaagattgct gtgcaagctc
     8761 gttgtgctta cttatttttt catacgtttg aaacgccatt gacgctctca aacccggtca
     8821 gcacctttcc tccagggctt gtccagttta gttcaggcac gaccggggta ccaaaacaat
     8881 tggagcgcag ttggtcatcg attgatgagg agctagctgc ttacaccgag cgtatggctc
     8941 gtgtggacgt cgatacggtc gtggttgcct gtccagtcac ccattcctat ggactcatta
     9001 gtggggtgtt agccggactg tcccaggata aggaggtagt tgtgttaact gcgcaaaatc
     9061 caaaatatgt acttaaaaaa ctaaccgatt atcccaacca tttgttgtat ggtgccccgc
     9121 cacttctgta cgcattggca aagctaagca atggggacac gcttcaggcc gtcatgacct
     9181 cgggaacacg tttgccagag gaatggtttc agtcaatcca atcaaacagc caaatgctgc
     9241 tgcaacaata tggttgctcg gaagctggct gtattagcat cgctatgcca cttcgttttt
     9301 ctgaagaatt gggcgtgccc cttcgccatg tacaggccaa agcagggacg gcgagaaaca
     9361 atcctagcga gattcaagtc accattggca gacgcacaat caacacaggc gatctaggct
     9421 acatcgatca agatggagct ctttgctttc gggaacgact ggacgacatg attaatgtcg
     9481 cgggtttgaa tgtttatcct cacgaagtcg aacacgtatt gcgcgaacat cctagcgtag
     9541 aagatgcggt cgtctataaa aaggcagatt cctatgcagg agagcgtgtt tgcgcgcaag
     9601 tgtctgccag aacggagacg ttatcccttc atgaattgcg gagctattgc atcagccggc
     9661 tagcgcctca tcaagttcca catgaaatga ccattgttga agagattgca aaaagcgcga
     9721 acggaaaagt aagccgcgta aagttaggag aagcaaaagg atgacgaaaa aggaagctat
     9781 ggatgcgatt tacacgattt tagagcatga attaaaattg ccaacgcttg aacagtttca
     9841 tcaagacgcg cgaatgaacg aagatctagc gcttgattcc attatgattt tgcagctttt
     9901 gcttgaacta gagatgaaat atggcgttgc catcccagat gagcacattg atataaaagc
     9961 attttacaca gtcggcgcat tggctgcgtt tgttgccgac aaacaggaag acccgcttta
    10021 tgattaaagt ccactgtttt gtcagttgca tatgcgaagt tcttaaaaaa agaggcattg
    10081 accatcgtcc ttattatttt ggtgtgtggg atgctgattt tgccatcgac gattcgtatg
    10141 ctttagctta tcattccgaa acaatcgacc attccttttt gaaaaactgg tatcgtcatt
    10201 tgtacggaat tgacatgcac gagtggtata aaaaggagca aacgaaagaa gccaatatcg
    10261 ccaagcttga aacgctgctt gaaacgaggc cttcatttcg caacgtaatg gtgatgcttg
    10321 atttggcgct tttgccagaa cgggaaaata aattccacca aaagccgttc cctcattatg
    10381 tgctgttaga aaaaacaggc acggaaagcc aatggcttat gctcgatccc gactaccgtt
    10441 gggaaggcgt catagaaaaa gagcggattt tagaggcgat ccgttcccct gacgtagggg
    10501 gtggctttta ttttgatgcg aaacagatcc atcagccgac gccagaaaca gtcgaggcct
    10561 attttcaaac atgtatgaag ttgcattcga atcctcttac cgaaggggtg agaacgattg
    10621 ttgaagccta tgtgaacgga agtgaaaagg cgcgttgttc agcgcttgcc gtagctttaa
    10681 aacagttacc tgtgctggcg attcgcaaat atgcgtatga acatgcgttt gcttactttt
    10741 ggaaggaact tggctttaag gaagctgaat ttgaagaatg gtgcgatgaa atcgagaaat
    10801 tggcgaaagg ctatacgacg attcattacc gggcaatgaa actttctcga accaaacatg
    10861 agcgggatta ccaagcggtg cttgctcaac tagaaaaaca agatctacgg gaaaggcgaa
    10921 tcaaacacag gctatacgat tattttaggg gatggaaaca attacaagaa atggctaggg
    10981 gggtgaacgc atgaatgtgt cgatttgtac catttctttt cgccatgcat tagtgtcgat
    11041 cgaacagctt gctgattggg cgaaggcgca cgatgtcgat ggaattgaat tgtgggcccc
    11101 tcatgcccgc cacttgtttg ccactccatc ctacaatggc gactggctta aaaaacaggg
    11161 cctgatcgta ccaatggtaa gcgattactt tccgctttat gaggaatgga atacattaat
    11221 agaggctgcc aaacaggcat cgcgtctatt gacgagatgg aatacgaacc atatccgcac
    11281 atttgccggt gcaaagggaa gcaaggatac gacaaaagca gaacgagcct atcttgtaaa
    11341 acggttagct tgtctttgtg actacttttt cgacaaaggg cactatgtgt tggttgaaac
    11401 acatccccat acgctatgtg atacagtccc atccacgctg caattgttgg cggaagtcga
    11461 tcatccaggg ttagcaatca attttgatgt ccttcatgta tgggaaagcg gagcggatgt
    11521 aaacgatgcg tttaaacaat tgcagcctca tatccgccat ctgcatgtaa aaaacattcg
    11581 ctcgccagaa gacttagatg tatttgcgcc tgaaaatgtt tatgctgctg ccggatctag
    11641 agagggaatg gccgggctgt ttaatggatc cgttgattac gagtcctttc tgtcagcgaa
    11701 tcaattggac ggcgtcaatg tatcgattga atggttcggg aacgatccgt ttcacgtgtt
    11761 agagcaagac tgcaagcaat taatgaaatg gaaaacagtc cccaatagag tggggcatta
    11821 gaagaattgc tttaacgggc cgcagctctc ttttgggcaa tgatccatgg aacggcggca
    11881 cgcaagtccg ggaagcgtgc gtctgcttgg aaatcgtcct cagtgcgtgc gtgaactaag
    11941 accgtttggc agcctgcctt ttggcccgcg cgaatgtctg gctcgcggtc gcctaccatg
    12001 acactcgcgg gcaagtcaac gtaatgtttg tccgctagtt ttttgagtaa ataggctttt
    12061 ggtttacggc aaggacatcc ttcattaggt ttatgggggc aataagcgat atcgtcgatt
    12121 gttgcccctt gcgcttttaa gtcggcctcc atttttttat ggatgagctc gagctttttt
    12181 tccttcatat agccaagacc tatgccgcct tgattggtaa caacaaagac gagaaagcca
    12241 gctttgttaa agaagcggat cgcttcggcc acaccatcca gcaagtggaa gtcgtttgca
    12301 tcgttaacga atttgacacg cttggataat acttcgttaa tgactccatc acggtctaaa
    12361 aaaacggctt gtttcaagtt gatcctccct ttcatgtttt taaatcctca gaagtgcaaa
    12421 agtgtcgttc ccatttacga tgtgcattta caaacaggaa tatcccgagc cggattgttc
    12481 ttacatgtgc taaagttaaa gaaaaaagga ggggataaac gtggacatag caggcaaaaa
    12541 cagagagcaa tggttggaag cttacccact tttacaacaa attgcattga caaaggaagt
    12601 gtggtgggcc aatccgaaca ggcagcctgc tagcgaaggg ctagcatgcc tttctttaaa
    12661 ggaagaggac gtgaaggaag cagaacagcg gttgcgacgc tttgccccat acatagcaag
    12721 cgtgtttccg gaaacgaaag gggcaggggg cttgatcgaa tcgccgctta tcgaaattcc
    12781 cacaatgaag cacaagcttg aacaacgatt tggccaaaac gtgccaggcc gacttttgct
    12841 gaaaggcgat cacgcgctgc ctatttcagg ctccattaaa gcgaggggcg gtatttatga
    12901 agtgttgaaa catgcggaaa gcttgttggt cgaccaacaa attctcacta aacaagacga
    12961 ttattcattg atcgccactg acgccgtcca atcgtttttc tcgtcttatg ccattgttgt
    13021 tggatcaaca ggtaatttag gattaagcat tggcatcatt agcgcaaagc taggttttcg
    13081 cgtgacggtg cacatgtcag ctgatgcaaa gcaatggaaa aaagacatgt tgcgagaaaa
    13141 aagcgtgcgt gtggtcgaac attccgccga ttacagcaag gcagtcgaag agggaagaaa
    13201 agaatcagac gccgatccga acagctattt tatcgatgac gaacattcaa ttgatctatt
    13261 tgtagggtat gctgtcgctg catttcgctt aaaagaacag ttgcaggaaa aggggattgc
    13321 cgtcacaaaa gaccaaccgc tccacgtcta tcttccatgt ggcgttggcg gcggtcctgg
    13381 cggggttgct ttcggcttga agctcgtttt cggtgacgct gtccgctgtt ttttcgcaga
    13441 gcctacccat tcgccatgta tgttaattgg tatgttaact ggaaagcacc agcacatttc
    13501 tgtccaagac tttggaatcg acaaccaaac ag
//
