LOCUS       c00030_JAIFOL0..        5953 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIFOL010000037.1 Lacticaseibacillus paracasei strain LB113R
            scaffold37_size17292, whole genome shotgun sequence.
ACCESSION   JAIFOL010000037
VERSION     JAIFOL010000037
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 22:48:23
            Original ID  :: JAIFOL010000037.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5953
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..141)
                     /locus_tag="ctg30_1"
                     /transl_table=11
                     /translation="MTHSQTNTHKHYQQLSFSDRATIQKLHRSKATISREITRGSVTQL
                     DS"
     protocluster    1..5953
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[507:953]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      508..953
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..5953
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5953
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(205..372)
                     /locus_tag="ctg30_2"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILPQ
                     FTIQVQHPDD"
     CDS             complement(508..723)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_3"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 8.7e-10,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(720..953)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_4"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.9e-15,
                     bitscore: 47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(1225..2178)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     220.3; E-value: 5.2e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_5"
                     /transl_table=11
                     /translation="MKQVRLGGFNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQLALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             2368..3117
                     /NRPS_PKS="Domain: PKS_KR (11-174). E-value: 3.9e-12.
                     Score: 38.2. Matches aSDomain:
                     nrpspksdomains_ctg30_6_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.8; E-value: 1.2e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_6"
                     /sec_met_domain="adh_short (E-value: 4.3e-35, bitscore:
                     111.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAVILTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTE
                     RLAELAASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAEL
                     KVNEWERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWA
                     IQAIMDGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVA
                     KAVLYAIDQPANVAINEVLLRPVTQER"
     aSDomain        2401..2889
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg30_6_PKS_KR.1"
                     /evalue="3.90E-12"
                     /label="ctg30_6_PKS_KR.1"
                     /locus_tag="ctg30_6"
                     /protein_end="174"
                     /protein_start="11"
                     /score="38.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     aSModule        2401..2889
                     /domains="nrpspksdomains_ctg30_6_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg30_6"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2404..2484
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg30_6_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg30_6"
                     /protein_end="39"
                     /protein_start="12"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             3143..4306
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     282.1; E-value: 9.6e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_7"
                     /transl_table=11
                     /translation="MSGYHFLKRFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPREGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTCLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGLKTPADAEKAADSFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSMTSSNVPQD"
     CDS             complement(4568..5944)
                     /locus_tag="ctg30_8"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITAAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAVKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIKSGDVTAAQFDKWVDPLKMTRA
                     "
ORIGIN
        1 cgagtcgagc tgagttacag atccacgcgt gatttctcgt gagattgtcg ctttactgcg
       61 atgaagcttc tgaattgtag cacggtcgct aaaactgagt tgttggtaat gcttgtgggt
      121 gttagtctga gagtgggtca tgaagattcc tgctttcttg tttagctagc actaacaaga
      181 ataggtcttc atggccttta tggtctagtc gtcagggtgt tgcacttgaa ttgtaaactg
      241 gggaagtatc ttggcaatga ctttgcttct tgctgcccct tgccaaagtc ctccaacaaa
      301 tggtgctaga taaaaagcga tcgtcgccag taaaatcaag ataactatga tgatacttat
      361 tatcttatcc atttgtattt cctcttcctt ttgcacaaat agactaattt gaaatcgatc
      421 tttgactaag acaagaaaaa gtgagcacta ccaaggtgtt agttatattg aacagttgcg
      481 ataggagcta accgtctttg tccaatatta ggctgggtga atgtaattag tgctgagaca
      541 caaggataat cctattgcag cgcctgcaac agttgtaaat ggatttaatc cagctgcccc
      601 tgctaccgct cccccgatcg tggacacaat acacccacta ggtttattgc gtcgcttggc
      661 tcctccttgg attaagacca aatcatgctg ttttaaagta atgcccactt ctttacttat
      721 cattgcatcc catctcctaa gcatttaata gctgacccaa ccgctcctaa gtttccacca
      781 actacggcgc cgccgattat cccaaaagga ccaccagcta ggccagtaat cgttcctgat
      841 ccaataccag ccgtgatgcc agtaacaaat gtagcagcac aatcaaattt ctttttccca
      901 cctgaaaccc ctgacaactg aaaatcgtca agctggcgat aattataaga cataattttc
      961 cttctttctt caaaaagcaa caagctattt tgtgtaaggt cgactttact gtctttaaca
     1021 tacattaatt atttgtgtaa aatgccaaaa ttttttaaac gtaggaaatt tccagtttaa
     1081 cgtcgtcttt acacttttat tgttcagttg cgctttaaaa gtcaaaaatt cttaacgttt
     1141 aaatctcctt gcttggtaaa aacttcaatt ttttgcaaaa aaaatcgtct cagcaatttg
     1201 agacaatttt ttcatatcat caacttacgg caagtcattc cccgccgcaa agtaaatgtc
     1261 ataccattcc tgtcgggtca acgtgatgtc cgcgccttcc gcactttcct tgatatgttc
     1321 aggattcata gagccgagaa tcacttgcac accgactgga tggcgtaata gccaagcgac
     1381 tgcgattgca tttttattgg tatggtagtg gtcagcgact ttctgcagtt catcattcaa
     1441 cgccttaaac ttcgggctat cgatgaaggt accttcaaac atgccgtatt ggaatggcga
     1501 ccaggcttgt aaggtcatgt gtttgcgttg caagtatggt agcaggctgc cgtcatgatc
     1561 gacagaagcc gcgtcggcca tgttggtgtg catccccgca ttgaccatac cagtgtgcgc
     1621 aacggagaac tgaacttggt cgatcagcaa aggctgccga atgccgcttt caagcaacgc
     1681 aagttgttca gggttaaagt tggagacgcc aaaatgccga accttgccgc tttgttccaa
     1741 tgcatcaaag gccgccgcaa cgtcatcgac ttccattaac ggatctggcc gatgcagcaa
     1801 gaccgaatca aggtaatcaa cctgcaaccg tttcaaaatg tgatcaaccg ctgacagtaa
     1861 gtgatctttt gaaaagtcgt accgtttgcc gaataccaaa ctgccatgag agcgttttgg
     1921 atcaacgacg atcccgactt tcgattgaat gaataactga tcgcgggaaa cgctggcttg
     1981 cttcaaggct tcaccaaaaa cttcttcgga tttgccttgg ccataaatgt cggccgagtc
     2041 gataaagttg atgccgtcat tgtacgcact atccagcaca ttggccgctt tgtcgggggc
     2101 cagcacattc atccgcatga tgcccaaggc cacacttgac gcctgccaat tgaatccgcc
     2161 taatcgaact tgtttcataa acacaaaact cccttcgata cgtcatttca aattatgtta
     2221 ctgacgacaa gttaagtgta gcccctaaag tccacttgag gtcaagccaa tattagaatt
     2281 tcaataaaac agcttgcatg gtgctgagct gcgcggtagg ttaagctgtg tctgttactt
     2341 attttttctt agcaggataa gcccataatg gaggccgtga ttttgacagt taaagataaa
     2401 gtggttgtaa tcacaggtgc atcgagcggg attggcgcgg caacggtaca agtgttggcc
     2461 gaggctggtg caaaactagt catcggtgcg cggcgcacag aacggttggc tgaattggcg
     2521 gccagcttta cggacggtca ggtgctttat caacaaaccg atgtgaccga ccagcagcaa
     2581 gtgaaagcgc tgattgattt ggcgttggat aagtttggtc atgtggatgt tttgtataac
     2641 aacgctggcc tgatgccact ttctgaaatg gccgaactca aagtcaacga atgggaacgt
     2701 atgattgacg tcaacattaa aggcgtcttg tatgggatcg ccgcggtttt accgcctatg
     2761 attgctcaac acagtggcca aattatcaca acagactcgg tcgccggtca cattgttcac
     2821 cctggaaccg ccgtttactc cggtaccaag tgggctatcc aggcgatcat ggacggcctg
     2881 cgacaagaac aagcggctaa tcatattaaa acgaccatga tctcgcccgg tgccgtgaat
     2941 actgagcttt tcagcacaat taccgatcct aagcgccgtg aagctgttga agccgatgaa
     3001 aaaaacaatg gcctcagcgc ctcggatgtt gccaaggcag ttttgtatgc cattgatcaa
     3061 ccggccaatg ttgccatcaa tgaagtgctc ttacggccag tcacgcaaga acgttaattt
     3121 tcgtctaaag gagtgtgatt gcatgtcggg ttatcatttt ttaaaacggt tcaccttcaa
     3181 gcaccaaacc atcacgttga aaaatcgcat tgtcattccg ccgatgacaa cgcgcctgtc
     3241 gtttgaagac ggcactgtga cgcgggacga aatcaggtat taccagcagc gggccggtgg
     3301 cgtcggcatg tttattaccg gtaccgccaa tgtcaatgcg cttggcaaag gattcgaagg
     3361 tgagctaagt gtcgctgatg atcgattcat ccccggtttg agcaaactcg ccgctgcgat
     3421 gaaaacaggc ggcaccaagg ctattttgca aatcttcagc gctggccgca tgagcaatag
     3481 caagattctg cgcggtgagc agccagtcag tgccagtgcg gttgctgcgc cacgggaggg
     3541 ttacgaaaca ccgcgcgcat tgacatcggc agaaatcgag gccactattc acgattttgg
     3601 tcaggctgtg cgccgcgcca tccttgctgg ttttgatggc atcgaactgc atggtgccaa
     3661 cacctgtctg atacagcaat tctattcgcc aaactctaat cgccgaaccg atgaatgggg
     3721 cggtgaccgc gataagcgga tgcgttttcc gttggcagtc gttcatgaag cagaaaaagt
     3781 gattgccaca attgctgacc ggccattttt gttaggctac cgcatttcgc cggaagagtt
     3841 ggaacagcct ggcattacct tggatgatac cttggcctta atcgacgctt tgaaacaaac
     3901 caagattgat tacctgcatg tctcccaaag tgacgtttgg cgaacctcat tgcgcaaccc
     3961 tgaggacaca gccatcatga atgaacaaat tcgtgaccac gtcgccggtg cttttccagt
     4021 gattgtggtt ggtggtctga aaacgccagc cgatgctgag aaagcggcag attcctttga
     4081 cttggtcgcc attggtcacg aaatgattcg cgagccgcac tgggttcaga aggtcttaga
     4141 ccatgacgaa aaggcgatcc gttaccagat cgcccctgct gatcttgaag aacttggcat
     4201 tgcgccgacc ttcctcgatt ttatcgaaag tatttccggt ggggcaaaag gtgtcccgtt
     4261 aacaactgcg cagtctatga catcaagcaa cgtgcctcaa gattaatcta gcatttcaaa
     4321 tcatcgtgcg agtcgagctg taaaaagctc ggcttttttc ttgccgtctt caacttacgc
     4381 gatggtgcct ggagctacca gtgatttata agttttaaat caaggtgtga tcatcacctg
     4441 ctcacgctct gatttaaacg cgttcaccag cgcagctcgg ctatgcgaag aacagtgaca
     4501 cagatggtcc aaagcccaga ccatctgtgt cactgccact tcgctacgcc gagctaaccg
     4561 cgccagctca cgctcttgtc atttttaacg ggtcgaccca tttatcaaac tgcgctgctg
     4621 tgacgtcgcc gcttttgatg gcggctgctt ttagatcgag gttttcttgc tcagccaatt
     4681 gcgcgatggc ggcacttttt tcgtagccga tgtggggtgc gagggcggtg accagcatga
     4741 gcgaatgatc aacgagtgct ctcatatgcg gtgcgtggat ggtcaagccg gcagctaatt
     4801 tttcagtgaa actcgtgact gttttggtta gtagatcagc tgactctaaa aaggtactga
     4861 tgataaccgg cttgtagacg ttcaattcaa aattgccttg tgacgcggcc accgtgatcg
     4921 tcgtatcgtt gcccatgact cgaacagcgg ccatggttag cgcttcggcc tgtgtgggat
     4981 tcactttgcc cggcatgatg gaactaccag gctcattggc cggaatgcgc aactcgccgt
     5041 atccagcacg tggaccactg gcaaggaagc gaatgtcatt ggcgatttta agcagatcag
     5101 ccgctagcgt tttaacggca ccatgaacaa cgctaatttc tgagtgagcc gctaaagcag
     5161 caaacttatt ggttttcgcc gaaagtggta attgataaac atcgctcaat cggcccgcca
     5221 caatcttgcc aaaattaggg tcagcgttaa gccccgttcc gactgctgtt ccgccaatgg
     5281 ctaagtaaaa aagattgggc tgaagctgct ttaaagcaat ctgatcatgc tccatcatgg
     5341 ccacccatcc gctgatttct tggccaaacg ttagcggcgt tgcatcctgt aaatgagttc
     5401 gaccgatttt aacaacacga gcgtaagtga cggcttttga atataaaaca ctgcacagtt
     5461 ggttgacagc gtgcagcaac tgattcactg caatagccgc cgtaatattc atcacagttg
     5521 gaaaagtatc attggagctt tggctgtgat tcacatcatc attcggtaag atcggcaagt
     5581 cggggttgag ttttgcagct tggtggctaa tgacttcgtt cacattcata tttgtttgtg
     5641 tgcctgaccc ggtttgataa acatgcagtg gaaaatcttt ttgcagtttt tcgtctggca
     5701 aggccaacaa ggcatcgact gctcgcgtga ttaattggcc ttttggtgcc ggtaaaacat
     5761 cagcggccac atttgctcgc gctgccgctt ttttgagttg cagcaaggcc ctaatcactg
     5821 gcatcggcat caatggacca gcctgaaaat tatgccggct gcgctctgtt tgcggtcccc
     5881 acaaagcgtt tgccggaatt tcaactggtc ctaatgtgtc cgtttctgtt cgatatttgc
     5941 tcatgtttac ctc
//
