GCA_019997305.1 - 20 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

JAIFZJ010000104 (original name was: JAIFZJ010000104.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	terpene	1	6,562

JAIFZJ010000010 (original name was: JAIFZJ010000010.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	transAT-PKS,NRPS,T3PKS	9,616	93,964	bacillaene	Polyketide + NRP	100%

JAIFZJ010000121 (original name was: JAIFZJ010000121.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 24.1	NRPS	1	3,708

JAIFZJ010000012 (original name was: JAIFZJ010000012.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	terpene	9,755	30,495

JAIFZJ010000017 (original name was: JAIFZJ010000017.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 88.1	transAT-PKS-like	1	46,649	difficidin	Polyketide + NRP	53%

JAIFZJ010000024 (original name was: JAIFZJ010000024.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 96.1	transAT-PKS	1	53,656	macrolactin H / macrolactin B / macrolactin 1c / macrolactin E	Polyketide	100%

JAIFZJ010000027 (original name was: JAIFZJ010000027.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 99.1	PKS-like	1	25,161	butirosin A / butirosin B	Saccharide	7%

JAIFZJ010000029 (original name was: JAIFZJ010000029.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 101.1	NRPS,transAT-PKS	1	46,634	bacillomycin D	Polyketide + NRP:Lipopeptide	60%

JAIFZJ010000002 (original name was: JAIFZJ010000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 102.1	NRPS	23,993	89,403	surfactin	NRP:Lipopeptide	82%

JAIFZJ010000032 (original name was: JAIFZJ010000032.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 105.1	transAT-PKS,NRPS	1	44,568	rhizocticin A	Other	6%

JAIFZJ010000003 (original name was: JAIFZJ010000003.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 113.1	other	97,927	139,345	bacilysin	Other	100%

JAIFZJ010000047 (original name was: JAIFZJ010000047.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 121.1	NRPS	1	30,555	bacillibactin	NRP	100%

JAIFZJ010000048 (original name was: JAIFZJ010000048.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 122.1	NRPS,betalactone	1	27,610	fengycin	NRP	73%

JAIFZJ010000051 (original name was: JAIFZJ010000051.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 126.1	transAT-PKS-like	1	23,214	difficidin	Polyketide + NRP	26%

JAIFZJ010000055 (original name was: JAIFZJ010000055.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 130.1	NRPS	1	21,278

JAIFZJ010000070 (original name was: JAIFZJ010000070.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 147.1	T3PKS	1	14,956

JAIFZJ010000072 (original name was: JAIFZJ010000072.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 149.1	transAT-PKS	1	14,754	difficidin	Polyketide + NRP	46%

JAIFZJ010000074 (original name was: JAIFZJ010000074.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 151.1	NRPS	1	14,062	fengycin	NRP	20%

JAIFZJ010000087 (original name was: JAIFZJ010000087.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 165.1	NRPS	1	9,379	fengycin	NRP	13%

JAIFZJ010000097 (original name was: JAIFZJ010000097.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 176.1	lanthipeptide-class-i	1	7,509	ericin S	RiPP:Lanthipeptide	35%

Region	Type	From	To	Most similar known cluster	Similarity
Region 5.1	terpene	1	6,562
Region 11.1	transAT-PKS,NRPS,T3PKS	9,616	93,964	bacillaene	Polyketide + NRP	100%
Region 24.1	NRPS	1	3,708
Region 33.1	terpene	9,755	30,495
Region 88.1	transAT-PKS-like	1	46,649	difficidin	Polyketide + NRP	53%
Region 96.1	transAT-PKS	1	53,656	macrolactin H / macrolactin B / macrolactin 1c / macrolactin E	Polyketide	100%
Region 99.1	PKS-like	1	25,161	butirosin A / butirosin B	Saccharide	7%
Region 101.1	NRPS,transAT-PKS	1	46,634	bacillomycin D	Polyketide + NRP:Lipopeptide	60%
Region 102.1	NRPS	23,993	89,403	surfactin	NRP:Lipopeptide	82%
Region 105.1	transAT-PKS,NRPS	1	44,568	rhizocticin A	Other	6%
Region 113.1	other	97,927	139,345	bacilysin	Other	100%
Region 121.1	NRPS	1	30,555	bacillibactin	NRP	100%
Region 122.1	NRPS,betalactone	1	27,610	fengycin	NRP	73%
Region 126.1	transAT-PKS-like	1	23,214	difficidin	Polyketide + NRP	26%
Region 130.1	NRPS	1	21,278
Region 147.1	T3PKS	1	14,956
Region 149.1	transAT-PKS	1	14,754	difficidin	Polyketide + NRP	46%
Region 151.1	NRPS	1	14,062	fengycin	NRP	20%
Region 165.1	NRPS	1	9,379	fengycin	NRP	13%
Region 176.1	lanthipeptide-class-i	1	7,509	ericin S	RiPP:Lanthipeptide	35%

No secondary metabolite regions were found in these records:: JAIFZJ010000100 (original name was: JAIFZJ010000100.1); JAIFZJ010000101 (original name was: JAIFZJ010000101.1); JAIFZJ010000102 (original name was: JAIFZJ010000102.1); JAIFZJ010000103 (original name was: JAIFZJ010000103.1); JAIFZJ010000105 (original name was: JAIFZJ010000105.1); JAIFZJ010000106 (original name was: JAIFZJ010000106.1); JAIFZJ010000107 (original name was: JAIFZJ010000107.1); JAIFZJ010000108 (original name was: JAIFZJ010000108.1); JAIFZJ010000109 (original name was: JAIFZJ010000109.1); JAIFZJ010000110 (original name was: JAIFZJ010000110.1); JAIFZJ010000111 (original name was: JAIFZJ010000111.1); JAIFZJ010000112 (original name was: JAIFZJ010000112.1); JAIFZJ010000113 (original name was: JAIFZJ010000113.1); JAIFZJ010000114 (original name was: JAIFZJ010000114.1); JAIFZJ010000115 (original name was: JAIFZJ010000115.1); JAIFZJ010000116 (original name was: JAIFZJ010000116.1); JAIFZJ010000117 (original name was: JAIFZJ010000117.1); JAIFZJ010000118 (original name was: JAIFZJ010000118.1); JAIFZJ010000119 (original name was: JAIFZJ010000119.1); JAIFZJ010000011 (original name was: JAIFZJ010000011.1); JAIFZJ010000120 (original name was: JAIFZJ010000120.1); JAIFZJ010000122 (original name was: JAIFZJ010000122.1); JAIFZJ010000123 (original name was: JAIFZJ010000123.1); JAIFZJ010000124 (original name was: JAIFZJ010000124.1); JAIFZJ010000125 (original name was: JAIFZJ010000125.1); JAIFZJ010000126 (original name was: JAIFZJ010000126.1); JAIFZJ010000127 (original name was: JAIFZJ010000127.1); JAIFZJ010000128 (original name was: JAIFZJ010000128.1); JAIFZJ010000129 (original name was: JAIFZJ010000129.1); JAIFZJ010000130 (original name was: JAIFZJ010000130.1); JAIFZJ010000131 (original name was: JAIFZJ010000131.1); JAIFZJ010000132 (original name was: JAIFZJ010000132.1); JAIFZJ010000133 (original name was: JAIFZJ010000133.1); JAIFZJ010000134 (original name was: JAIFZJ010000134.1); JAIFZJ010000135 (original name was: JAIFZJ010000135.1); JAIFZJ010000136 (original name was: JAIFZJ010000136.1); JAIFZJ010000137 (original name was: JAIFZJ010000137.1); JAIFZJ010000138 (original name was: JAIFZJ010000138.1); JAIFZJ010000139 (original name was: JAIFZJ010000139.1); JAIFZJ010000013 (original name was: JAIFZJ010000013.1); JAIFZJ010000140 (original name was: JAIFZJ010000140.1); JAIFZJ010000141 (original name was: JAIFZJ010000141.1); JAIFZJ010000142 (original name was: JAIFZJ010000142.1); JAIFZJ010000143 (original name was: JAIFZJ010000143.1); JAIFZJ010000144 (original name was: JAIFZJ010000144.1); JAIFZJ010000145 (original name was: JAIFZJ010000145.1); JAIFZJ010000146 (original name was: JAIFZJ010000146.1); JAIFZJ010000147 (original name was: JAIFZJ010000147.1); JAIFZJ010000148 (original name was: JAIFZJ010000148.1); JAIFZJ010000149 (original name was: JAIFZJ010000149.1); JAIFZJ010000014 (original name was: JAIFZJ010000014.1); JAIFZJ010000150 (original name was: JAIFZJ010000150.1); JAIFZJ010000151 (original name was: JAIFZJ010000151.1); JAIFZJ010000152 (original name was: JAIFZJ010000152.1); JAIFZJ010000153 (original name was: JAIFZJ010000153.1); JAIFZJ010000154 (original name was: JAIFZJ010000154.1); JAIFZJ010000155 (original name was: JAIFZJ010000155.1); JAIFZJ010000156 (original name was: JAIFZJ010000156.1); JAIFZJ010000157 (original name was: JAIFZJ010000157.1); JAIFZJ010000158 (original name was: JAIFZJ010000158.1); JAIFZJ010000159 (original name was: JAIFZJ010000159.1); JAIFZJ010000015 (original name was: JAIFZJ010000015.1); JAIFZJ010000160 (original name was: JAIFZJ010000160.1); JAIFZJ010000161 (original name was: JAIFZJ010000161.1); JAIFZJ010000162 (original name was: JAIFZJ010000162.1); JAIFZJ010000163 (original name was: JAIFZJ010000163.1); JAIFZJ010000164 (original name was: JAIFZJ010000164.1); JAIFZJ010000165 (original name was: JAIFZJ010000165.1); JAIFZJ010000166 (original name was: JAIFZJ010000166.1); JAIFZJ010000167 (original name was: JAIFZJ010000167.1); JAIFZJ010000168 (original name was: JAIFZJ010000168.1); JAIFZJ010000169 (original name was: JAIFZJ010000169.1); JAIFZJ010000016 (original name was: JAIFZJ010000016.1); JAIFZJ010000170 (original name was: JAIFZJ010000170.1); JAIFZJ010000171 (original name was: JAIFZJ010000171.1); JAIFZJ010000172 (original name was: JAIFZJ010000172.1); JAIFZJ010000173 (original name was: JAIFZJ010000173.1); JAIFZJ010000174 (original name was: JAIFZJ010000174.1); JAIFZJ010000175 (original name was: JAIFZJ010000175.1); JAIFZJ010000176 (original name was: JAIFZJ010000176.1); JAIFZJ010000177 (original name was: JAIFZJ010000177.1); JAIFZJ010000178 (original name was: JAIFZJ010000178.1); JAIFZJ010000179 (original name was: JAIFZJ010000179.1); JAIFZJ010000018 (original name was: JAIFZJ010000018.1); JAIFZJ010000019 (original name was: JAIFZJ010000019.1); JAIFZJ010000001 (original name was: JAIFZJ010000001.1); JAIFZJ010000020 (original name was: JAIFZJ010000020.1); JAIFZJ010000021 (original name was: JAIFZJ010000021.1); JAIFZJ010000022 (original name was: JAIFZJ010000022.1); JAIFZJ010000023 (original name was: JAIFZJ010000023.1); JAIFZJ010000025 (original name was: JAIFZJ010000025.1); JAIFZJ010000026 (original name was: JAIFZJ010000026.1); JAIFZJ010000028 (original name was: JAIFZJ010000028.1); JAIFZJ010000030 (original name was: JAIFZJ010000030.1); JAIFZJ010000031 (original name was: JAIFZJ010000031.1); JAIFZJ010000033 (original name was: JAIFZJ010000033.1); JAIFZJ010000034 (original name was: JAIFZJ010000034.1); JAIFZJ010000035 (original name was: JAIFZJ010000035.1); JAIFZJ010000036 (original name was: JAIFZJ010000036.1); JAIFZJ010000037 (original name was: JAIFZJ010000037.1); JAIFZJ010000038 (original name was: JAIFZJ010000038.1); JAIFZJ010000039 (original name was: JAIFZJ010000039.1); JAIFZJ010000040 (original name was: JAIFZJ010000040.1); JAIFZJ010000041 (original name was: JAIFZJ010000041.1); JAIFZJ010000042 (original name was: JAIFZJ010000042.1); JAIFZJ010000043 (original name was: JAIFZJ010000043.1); JAIFZJ010000044 (original name was: JAIFZJ010000044.1); JAIFZJ010000045 (original name was: JAIFZJ010000045.1); JAIFZJ010000046 (original name was: JAIFZJ010000046.1); JAIFZJ010000049 (original name was: JAIFZJ010000049.1); JAIFZJ010000004 (original name was: JAIFZJ010000004.1); JAIFZJ010000050 (original name was: JAIFZJ010000050.1); JAIFZJ010000052 (original name was: JAIFZJ010000052.1); JAIFZJ010000053 (original name was: JAIFZJ010000053.1); JAIFZJ010000054 (original name was: JAIFZJ010000054.1); JAIFZJ010000056 (original name was: JAIFZJ010000056.1); JAIFZJ010000057 (original name was: JAIFZJ010000057.1); JAIFZJ010000058 (original name was: JAIFZJ010000058.1); JAIFZJ010000059 (original name was: JAIFZJ010000059.1); JAIFZJ010000005 (original name was: JAIFZJ010000005.1); JAIFZJ010000060 (original name was: JAIFZJ010000060.1); JAIFZJ010000061 (original name was: JAIFZJ010000061.1); JAIFZJ010000062 (original name was: JAIFZJ010000062.1); JAIFZJ010000063 (original name was: JAIFZJ010000063.1); JAIFZJ010000064 (original name was: JAIFZJ010000064.1); JAIFZJ010000065 (original name was: JAIFZJ010000065.1); JAIFZJ010000066 (original name was: JAIFZJ010000066.1); JAIFZJ010000067 (original name was: JAIFZJ010000067.1); JAIFZJ010000068 (original name was: JAIFZJ010000068.1); JAIFZJ010000069 (original name was: JAIFZJ010000069.1); JAIFZJ010000006 (original name was: JAIFZJ010000006.1); JAIFZJ010000071 (original name was: JAIFZJ010000071.1); JAIFZJ010000073 (original name was: JAIFZJ010000073.1); JAIFZJ010000075 (original name was: JAIFZJ010000075.1); JAIFZJ010000076 (original name was: JAIFZJ010000076.1); JAIFZJ010000077 (original name was: JAIFZJ010000077.1); JAIFZJ010000078 (original name was: JAIFZJ010000078.1); JAIFZJ010000079 (original name was: JAIFZJ010000079.1); JAIFZJ010000007 (original name was: JAIFZJ010000007.1); JAIFZJ010000080 (original name was: JAIFZJ010000080.1); JAIFZJ010000081 (original name was: JAIFZJ010000081.1); JAIFZJ010000082 (original name was: JAIFZJ010000082.1); JAIFZJ010000083 (original name was: JAIFZJ010000083.1); JAIFZJ010000084 (original name was: JAIFZJ010000084.1); JAIFZJ010000085 (original name was: JAIFZJ010000085.1); JAIFZJ010000086 (original name was: JAIFZJ010000086.1); JAIFZJ010000088 (original name was: JAIFZJ010000088.1); JAIFZJ010000089 (original name was: JAIFZJ010000089.1); JAIFZJ010000008 (original name was: JAIFZJ010000008.1); JAIFZJ010000090 (original name was: JAIFZJ010000090.1); JAIFZJ010000091 (original name was: JAIFZJ010000091.1); JAIFZJ010000092 (original name was: JAIFZJ010000092.1); JAIFZJ010000093 (original name was: JAIFZJ010000093.1); JAIFZJ010000094 (original name was: JAIFZJ010000094.1); JAIFZJ010000095 (original name was: JAIFZJ010000095.1); JAIFZJ010000096 (original name was: JAIFZJ010000096.1); JAIFZJ010000098 (original name was: JAIFZJ010000098.1); JAIFZJ010000099 (original name was: JAIFZJ010000099.1); JAIFZJ010000009 (original name was: JAIFZJ010000009.1)

Compact view

c00005_JAIFZJ0.. - Region 1 - terpene

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Location: 1 - 6,562 nt. (total: 6,562 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

No matches found.

c00011_JAIFZJ0.. - Region 1 - NRPS,T3PKS,transAT-PKS

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Location: 9,616 - 93,964 nt. (total: 84,349 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))
T3PKS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 9615 - 93964:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal - mal) + (ccmal - ohmal - mal) + (X - ccmal - ccmal - ccmal) + (mal - mal - ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg11_29

Search NORINE for peptide: strict or relaxed

AMP-binding (492..896): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVsnmAiIYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

ctg11_32

Search NORINE for peptide: strict or relaxed

CAL_domain (74..476): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 26.7
NH2: 9.4
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1145..1540): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg11_37

PKS_AT (4..282): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 92.8
inactive: 28.2
Methoxymalonyl-CoA: 23.4
Methylmalonyl-CoA: 11.0
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg11_38

PKS_AT (7..293): mal

ATSignature: (unknown)

No matches above 50%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 35.4
inactive: 26.4
Methoxymalonyl-CoA: 14.9
Benzoyl-CoA: 14.0
Methylmalonyl-CoA: 9.2
Isobutyryl-CoA: 8.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg11_39

PKS_AT (8..289): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 100.0
inactive: 46.8
Methoxymalonyl-CoA: 38.9
Methylmalonyl-CoA: 25.3
Propionyl-CoA: 23.1
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

c00024_JAIFZJ0.. - Region 1 - NRPS

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Location: 1 - 3,708 nt. (total: 3,708 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 3708:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg24_1

Search NORINE for peptide: strict or relaxed

AMP-binding (463..868): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

c00033_JAIFZJ0.. - Region 1 - terpene

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Location: 9,755 - 30,495 nt. (total: 20,741 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

No matches found.

c00088_JAIFZJ0.. - Region 1 - transAT-PKS-like

Download region GenBank file

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Location: 1 - 46,649 nt. (total: 46,649 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 46649:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - mal) + (mal - ccmal) + (mal - ohmal - mal) + (ccmal - mal)
Non-colinear ordering:: ctg88_1 + ctg88_3 + ctg88_2 + ctg88_4

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

c00096_JAIFZJ0.. - Region 1 - transAT-PKS

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Location: 1 - 53,656 nt. (total: 53,656 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 53656:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - mal) + (ccmal - mal) + (ccmal - ccmal) + (ohmal - ccmal - ccmal) + (ccmal - mal - ccmal) + (ohmal - mal - ohmal)
Non-colinear ordering:: ctg96_4 + ctg96_5 + ctg96_7 + ctg96_8 + ctg96_6 + ctg96_9 + ctg96_3

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg96_9

PKS_AT (37..315): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 91.9
inactive: 31.2
Methoxymalonyl-CoA: 26.1
Methylmalonyl-CoA: 19.6
Propionyl-CoA: 16.9
fatty_acid: 13.9
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

c00099_JAIFZJ0.. - Region 1 - PKS-like

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Location: 1 - 25,161 nt. (total: 25,161 nt) Show pHMM detection rules used

Region on contig edge.

PKS-like: (t2pks2 or ksIII)

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KnownClusterBlast

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c00101_JAIFZJ0.. - Region 1 - NRPS,transAT-PKS

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Location: 1 - 46,634 nt. (total: 46,634 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

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NRPS/PKS domains

KnownClusterBlast

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 46634:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal - asn) + (D-tyr - D-asn - gln - pro) + (D-asn - ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg101_8

Search NORINE for peptide: strict or relaxed

AMP-binding (255..650): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (1765..2172): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg101_9

Search NORINE for peptide: strict or relaxed

AMP-binding (189..583): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DALSVGEVVK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

AMP-binding (1700..2095): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (3209..3614): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDLGVVDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 100% (strong)

AMP-binding (4258..4654): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

ctg101_10

Search NORINE for peptide: strict or relaxed

CAL_domain (36..478): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 624.6
NH2: 18.6
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (2956..3351): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg101_11

PKS_AT (6..290): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 72.2
inactive: 30.7
Methoxymalonyl-CoA: 19.0
Propionyl-CoA: 9.7
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Methylmalonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

c00102_JAIFZJ0.. - Region 1 - NRPS

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Location: 23,993 - 89,403 nt. (total: 65,411 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

KnownClusterBlast

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 23992 - 89403:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - leu - D-leu) + (val - asp - D-leu) + (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg102_40

Search NORINE for peptide: strict or relaxed

AMP-binding (465..867): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1511..1908): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

AMP-binding (2550..2940): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

ctg102_41

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (1502..1904): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

AMP-binding (2547..2936): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

ctg102_42

Search NORINE for peptide: strict or relaxed

AMP-binding (469..867): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

c00105_JAIFZJ0.. - Region 1 - NRPS,transAT-PKS

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Location: 1 - 44,568 nt. (total: 44,568 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 44568:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - D-phe) + (X - D-asn - gly) + (ccmal) + (D-glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg105_1

Search NORINE for peptide: strict or relaxed

AMP-binding (248..645): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAfWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (1287..1678): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTIAAICK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 100% (strong)

ctg105_2

Search NORINE for peptide: strict or relaxed

AMP-binding (264..665): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGhVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

AMP-binding (1303..1697): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (2805..3198): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQmGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

ctg105_3

PKS_AT (6..293): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 75.0%; 2-Methylbutyryl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 111.1
inactive: 50.8
Methoxymalonyl-CoA: 39.3
Isobutyryl-CoA: 31.6
Methylmalonyl-CoA: 29.7
Propionyl-CoA: 12.0
CHC-CoA: 10.8
fatty_acid: 10.4
Benzoyl-CoA: 10.0
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg105_7

Search NORINE for peptide: strict or relaxed

AMP-binding (1200..1601): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDIGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

c00113_JAIFZJ0.. - Region 1 - other

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Location: 97,927 - 139,345 nt. (total: 41,419 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

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KnownClusterBlast

Similar known gene clusters

c00121_JAIFZJ0.. - Region 1 - NRPS

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Location: 1 - 30,555 nt. (total: 30,555 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

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Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 30555:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg121_18

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

ctg121_20

Search NORINE for peptide: strict or relaxed

AMP-binding (480..879): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1537..1953): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

c00122_JAIFZJ0.. - Region 1 - NRPS,betalactone

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Location: 1 - 27,610 nt. (total: 27,610 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

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NRPS/PKS domains

KnownClusterBlast

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27610:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-tyr) + (ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg122_1

Search NORINE for peptide: strict or relaxed

AMP-binding (202..594): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

ctg122_2

Search NORINE for peptide: strict or relaxed

AMP-binding (473..866): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

ctg122_6

Search NORINE for peptide: strict or relaxed

AMP-binding (12..445): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gclhIAApvK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 40% (weak)

c00126_JAIFZJ0.. - Region 1 - transAT-PKS-like

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Location: 1 - 23,214 nt. (total: 23,214 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

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KnownClusterBlast

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 23214:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (mal) + (ccmal) + (mal - ohmal - mal) + (mal - mal)
Non-colinear ordering:: ctg126_2 + ctg126_5 + ctg126_3 + ctg126_4

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

c00130_JAIFZJ0.. - Region 1 - NRPS

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Location: 1 - 21,278 nt. (total: 21,278 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

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Similar known gene clusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 21278:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-cys - ser - cys - ala) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg130_1

Search NORINE for peptide: strict or relaxed

CAL_domain (168..474): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 72.8
Acetyl-CoA: 26.6
NH2: 24.7
shikimic_acid: 0.0
AHBA: 0.0

AMP-binding (1130..1514): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSLiWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

AMP-binding (2620..3019): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWqIiLVnK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 70% (weak)

AMP-binding (3938..4322): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSLiWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

AMP-binding (4965..5358): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DVWCIAmvYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 80% (moderate)

ctg130_2

Search NORINE for peptide: strict or relaxed

AMP-binding (299..684): X

NRPSPredictor2: tyr, bht

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DqgSeGtVnK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 50% (weak)

c00147_JAIFZJ0.. - Region 1 - T3PKS

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Location: 1 - 14,956 nt. (total: 14,956 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00149_JAIFZJ0.. - Region 1 - transAT-PKS

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Location: 1 - 14,754 nt. (total: 14,754 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

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core biosynthetic genes

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 14754:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg149_3

Search NORINE for peptide: strict or relaxed

AMP-binding (15..363): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: iGnpTGtifK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 40% (weak)

ctg149_6

PKS_AT (4..281): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 87.7
inactive: 30.9
Methoxymalonyl-CoA: 29.3
Methylmalonyl-CoA: 21.7
Propionyl-CoA: 16.5
2-Methylbutyryl-CoA: 15.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

c00151_JAIFZJ0.. - Region 1 - NRPS

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Location: 1 - 14,062 nt. (total: 14,062 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 14062:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-orn) + (tyr - D-thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg151_1

Search NORINE for peptide: strict or relaxed

AMP-binding (468..851): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

ctg151_2

Search NORINE for peptide: strict or relaxed

AMP-binding (474..867): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DGTLTAEVAK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

AMP-binding (1509..1905): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg151_3

Search NORINE for peptide: strict or relaxed

AMP-binding (203..608): orn

NRPSPredictor2: orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEVGSIDK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 100% (strong)

c00165_JAIFZJ0.. - Region 1 - NRPS

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Location: 1 - 9,379 nt. (total: 9,379 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 9379:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-val) + (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg165_1

Search NORINE for peptide: strict or relaxed

AMP-binding (469..866): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

AMP-binding (1500..1879): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGSVEK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

ctg165_2

Search NORINE for peptide: strict or relaxed

AMP-binding (193..586): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

c00176_JAIFZJ0.. - Region 1 - lanthipeptide-class-i

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Location: 1 - 7,509 nt. (total: 7,509 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03882))

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core biosynthetic genes

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Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptide(s) for ctg176_1 - Putative Class I

allorf_5427_5606 leader / core peptide: VTNMSKFDDFDLDVVKVSKQDSKITPQ - WKDhaEDhaVCDhbPGCVDhbGVLQDhbCFLQDhbIDhbCNCHIDhaK

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Similar known gene clusters

Lanthipeptides

Core peptide predictions

allorf_5427_5606 - Class I

Cleavage pHMM score: 27.80

RODEO score: 24

Monoisotopic mass: 3341.6 Da

Molecular weight: 3343.9 Da

Number of bridges: 5

Alternative weights: (assuming N unmodified Ser/Thr residues); 3361.9 Da N = 1; 3379.9 Da N = 2; 3398.0 Da N = 3