LOCUS       c00010_JAINRO0..       22908 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAINRO010000010.1 Ligilactobacillus salivarius strain AER36
            contig00010, whole genome shotgun sequence.
ACCESSION   JAINRO010000010
VERSION     JAINRO010000010
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 12:17:39
            Original ID  :: JAINRO010000010.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22908
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22908
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6941:12908]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6942..12908
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..22908
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22908
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     CDS             93..887
                     /locus_tag="ctg10_1"
                     /transl_table=11
                     /translation="VTEPKELGYLALYYQMEIEDEKRGNPQYHKVAIVGEVSKSIQNLI
                     ISRLNETFQGTTEADIFKSSESFKKSSERYLIVFSTLPLESKDVTTPIVRIQSIFKNDE
                     LVSKVTLSQVMAGISSQQVKFRIQRFEERISYLKAVENLIDTEISTGELLPGFKLDWKK
                     REEKMSNVFQNGIAIPHMVDKSNHSRILLTVGILSKAVKYQGKEVRIIFLIGIPQNLNS
                     KLSKILSHVYDLIFMISGYDEIYNNLLEYDMDLPLTQITEGI"
     CDS             888..1385
                     /locus_tag="ctg10_2"
                     /transl_table=11
                     /translation="MIILIGLIVVGAFLLQGLFGIFQIKNFSRNYRELRLLGPYRILIG
                     KNPKRFFSGSLMLIAIDNDGNIKEARLMQGVTVFAKFRTLKKLEGKNIAVLAADYQELK
                     RMNKLTRQCLLNAYKTFVDFKTQKLSASAYDTSVNVFNMPLFTKIGLMANNLKVNMSKK
                     FN"
     CDS             1397..1939
                     /locus_tag="ctg10_3"
                     /transl_table=11
                     /translation="MDIVVNLASGFMNLFETGGKTFIGWMKTIVPVVLLLLVLMNTIIA
                     FLGEEKMDKIARGASKNIFTRYLILPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQAQ
                     FCHTSNGVFPHINPGELFVWMGIAQGVQKLGLNSMDLAIRYLLVGLVMNFIGGWVTDFT
                     TAYVCRTTGIKLSKTVD"
     CDS             1956..2981
                     /locus_tag="ctg10_4"
                     /transl_table=11
                     /translation="MSKWNSIKIVKGSGGWGGPIVVTPTEEKHKVVYVTGGNRPDIVDT
                     IVELTGMEAIDGFKTAIPDEEIALAIVDCGGTLRCGIYPSKNILTVNVLPTGKSGPLAK
                     YITPELYVSAVTPKQISLVNAEDAEAIVKQQNEKATKEETAADKEDGIDTSKTLTQQGH
                     GGGFIAKIGIGVGKVVATFNQAAKESVQTVLNTIIPFMAFVALLIGIIMGSGIGNWFAK
                     IMVPLADNVWGLMILGFICSLPFLSPLLGPGAVIAQVIGTLIGVEIGKGHIPPQYALPA
                     LFAINTQNACDFIPVGLGLEEAKPETVEVGVTSVLYSRFLNGLPRVFVAWLASFGLYSG
                     K"
     CDS             3018..3398
                     /locus_tag="ctg10_5"
                     /transl_table=11
                     /translation="MFLQKKKTKLYETEVIEIGEEAKNFKEIKMVILFGEGAPDALRPS
                     CYIIKVNELSGEIKAGMTLQIDDEKYKITAVGNEVQTNLKNLGHIAINFTGDKTATLPG
                     SMYVEEKEYPEINEGTKIAIIK"
     CDS             3465..4145
                     /locus_tag="ctg10_6"
                     /transl_table=11
                     /translation="MEFLLDTVDLKKIKYYCDKLNVKGVTSNPTILKKDGVGDDLFAHL
                     KKIKEIIGDERELHVQVVAPSVSGMIDEAHKIIDEVGKDVYIKVPTTLDGLEVMKKLKA
                     EGIRVTATAIYTEFQGYQAINVGADYLAPYYNRMLNQNIDSAEVIRNLAKRINLDNSNT
                     KILAASFHNVAQVNEALSNGAQAVTVGPDIVASAFKMPSISQAVADFRNDWESLYGDKN
                     INNL"
     CDS             complement(4206..5201)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 307.1; E-value: 1.7e-93)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MVSIKMFGVRDEERPMAENWAKEHNVKIDMTSDILTSDTIDEVKG
                     FDGLTLMQVAEVTDDLYPKLKEFGIKQIAQRSAGYDMYNLDAAKENGIIITNVPSYSPE
                     SIAEYTVTTALNLIRKFPLIEKRVKEHNFSWEPEIRGRVIGDMTVAVIGTGRIGYHVAK
                     IFHGFGAKVVGYDLYPSDKLDGILEYRDSVEDAIRDADIISLHMPAFKENHHMFNYEMF
                     KKFKSDAVLVNMARGALIDTEDLLKALDDGLLAGAGLDVYEHEGPLVPIDLTGKDIEDE
                     TFKKVLESDKIIYSPHVAYYTDEAVRNLVEGGLNATLEVLETGDASTRVN"
     CDS             5408..6457
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="LETTKITPKVFIDRVLGGTAIGIIVGLIPNAVLAAILKMFGTNPF
                     AVHLGQAAIIFQLGTPLIIGTLIAQKFGFDGMKMTVVGGAAFVGSGVIKYFPALNKTGA
                     YVGAGTGDIINTMLTASIAVGLILLIGDKFGSVAIVLTPIVVGAGAGLIGFYMYPYVTA
                     ITSAIGNVINTFTELQPVLMCILIACSFAVLIISPISTVAIAMAIQVNGLAAGAAAMGV
                     AATTLVLVVNSWKVNKPGVTIAIALGAMKMMMPNLFRRPIILVPCFFTAIISAVPVALM
                     SISGSPASGGFGLVGLVGPLASIEKGLGVVAALLAWLVIPVIASLVGQFLFEKVFKLYD
                     RKDVFEFLG"
     CDS             6684..6863
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_a"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_9"
                     /sec_met_domain="TIGR03731 (E-value: 1.4e-16, bitscore:
                     52.3, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_a (E-value: 4e-07, bitscore: 21.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVNDFKLDLVKVSKESTNSNYSVKITSYSLCTPGCKTGALMGCT
                     MKTASCGCHVHISK"
     CDS_motif       6684..6758
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSVNDFKLDLVKVSKESTNSNYSVK"
                     /locus_tag="ctg10_9"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6759..6863
                     /prepeptide="core"
                     /locus_tag="ctg10_9"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="12.40"
                     /molecular_weight="3329.0"
                     /monoisotopic_mass="3326.6"
                     /core_sequence="ITSYSLCTPGCKTGALMGCTMKTASCGCHVHISK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSVNDFKLDLVKVSKESTNSNYSVK"
                     /leader_location="[6683:6758](+)"
                     /alternative_weights="3347.0"
                     /alternative_weights="3365.0"
                     /alternative_weights="3383.0"
                     /alternative_weights="3401.1"
     CDS             6942..9902
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     737.7; E-value: 3.1e-223)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_10"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.7e-90, bitscore:
                     294.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.4e-23, bitscore:
                     75.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.9e-11,
                     bitscore: 36.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFNVSDVMIRNTIQTYEKSQNFNNYKEFIEIIKNDDIFLEQIL
                     LANPKLYGMLKKYNAGKLKKKKEKNFFESIYKYYKRSYYRATPFGLFSETSNGKFAVKG
                     DKKGLGKTHKVVFIDIKWLTDVIFKLEKDYQSNLSFISNNGNYISGNRVMQLYSINDQN
                     LEEVSINNSKVYQIISEECSQTYKTYSEIIEKVITIYGNEYLNLTKEYINDLVENHYLI
                     SNLQENILINFSMSDFIMKVKEIDISKKYVEILTKIQELIEEYTHIEIGSGSDKLIEIY
                     HQMARLNKSDNYIQVDLYNDGNIYIDNSNKQRIEKFSNFITNTVKSVTRTYFDDYKDKF
                     IEKYGIDQGVQLIELFDPIKGIGAPYDYTHPQNEVFELEPPTSYYSHDEKEMYINKYIE
                     ALLNREEINLKCFSNYYGNLNSKESTSIQGIELFFHIVQINKKKTLALSNIIGSNNIGG
                     SSGRFSLLSDKLRDYHMKTLKQVKVANIEEGVTSCEIVFLPENIRHANIMRTSFVREKV
                     LPIFSSTDQSEVRLTNIYIGLDENENFYAYDVSTQEKMKFYVTSMYNKTLFSNELRFLC
                     EISINNNFGYVPWDLIYKDMNFIPRIMFEDIVVSPKTWRIFKFELSNIAIESIIKQRNI
                     PNEIYIVDGDNKLYINRKNSLDVELFMSEIKRNIEKNGYAIIQEYFNNKDMIYKDNEGK
                     ISEIVVPVINSKFDVKKVNKEKQQRISKHVREKLPFNDWLYLKVYMSTRRQEEFIRVYI
                     PLIQKKVEKLDGKLFFLRYMDPVPQIRIRISGNNLYKIYEIIKKDLEKGHRNGILSTFD
                     ISTYDREIERYGGVNAIDIAENIFCEDSKLVIKYLKFIKEKNMEDKLDDIAVAMIYFYL
                     KIFYKTNEDILCFLDKVCPNKVDKNVRSKIQYYKSVVFNQLTDIYEIDKYNFNRLKEEI
                     IKLKLIIDKKNADTIMDSIIHVHNNRLFGINRVREQNLYFIVKKIIMSEKYILKGK"
     CDS             9902..11722
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 170; E-value:
                     1.1e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="MMDEIKKLTSKNFFKTLLTLPDTIKLIFQLERKYATYLMCLNIVT
                     ALIPLLNLIVYQNLINSIFSRGMQLVYNIIYFLILQIFTVILSQLEDYINGKFNMWLSY
                     NINLKLIKKTTSLKLTDYEQSDMYNLIEKITQDSTYKPFQLFNAVIAMLAAFISLLTSL
                     IFVAAWNIWIGLLLLVTPMLSLIIFLKVGQLEFLIQWKRASAERKSWYIVYLLTHDFSF
                     KEIKLNNLSDYFVEEYKKLKKDFILQDLLIARKKAYFNSGLQILLDFINIFVICTIIVS
                     VQAGRILIGNLVSLMQATTKINGYSQTIIQNIYIIYNTSLFMEQLLNFLKIENQSDYRK
                     NIGIGDENRIKRIDLIDVEYKYPNSSVNALEKINFSMHTGELIAIIGENGSGKSTLVKL
                     ISGLYTPSKGHIYYNGIEDKHISTDFYQKNISILFQDFVKYELTLRENIGLGNIAEKWD
                     DNKIIHIMDKLRLNFLKENGEYNLNLQLGTWFQNGRQLSGGQWQKIALARAFFKNASVY
                     ILDEPSAALDPISEKEIFDYFVNLSKDNISIFISHDLNVARKASKIIVMNKGRVVGIGT
                     HEELLKDCSFYQELYWAEKYGRNKKKNFKK"
     CDS             11688..12908
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     275.3; E-value: 1.3e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_12"
                     /sec_met_domain="LANC_like (E-value: 5e-57, bitscore:
                     185.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKRKILKNKFSRVILEWDRRIEQNAYRYNFEEFTLSSGLPGV
                     ILLLLEMEDLDRAYKFKIDQYCDYLYGKLSKYGLLTGSLYSGAAGIALSLLPLKKDLRF
                     QNLIASLNDYISYYVDKEIGEFNIENVTPPNYDVIEGLSGILMYLLLIDNIDIKLVTKI
                     IIFLLTLLDDNDSLIAMYIKTGNQMSEAENEIYPNGCLNTGMSHGLAGVGSVLAYAYKK
                     GFMKKEILHGLERIIQIYEKFELVDKNKFHWKDGIDYNELVNNRTILKDNDLFIRDAWC
                     YGSPGISVLYLYIGLIQDNSYLIKKAIEILYRATKEMRNVDSNMICHGKSGIVSICILF
                     RKLIKTRKFDTFINNYTDEIESIFDKDIRNLGFLEGTTGIILTLNECFSNKGKTQWMKS
                     LMLFDDF"
     CDS             12945..13634
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 167.3; E-value: 6.2e-51)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg10_13"
                     /transl_table=11
                     /translation="MYRILVIDDDVEILKLMKTALEMKNYEVVTCQNVHVPLKLSDFEG
                     FNLILLDIMMSKISGTEICYQIRSKISTPIIFISAKDDEEDILYGLKIGGDDYITKPFS
                     LKQLLAKIDANIKREERSRQAVQDFAEVKRDMGKITFYLEERRVCVNSQDIPLTSREYD
                     ILELLSRRASHIYSREDIYNNVYDEYAETLFGSISEYIYQIRTKFAPFKLNPVQTIRGV
                     GYKWYEE"
     CDS             13624..14967
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 113.7; E-value: 2.1e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg10_14"
                     /transl_table=11
                     /translation="MKNKIHSMKWRIWKTAFEIFIETFLGLGLLLAITFILQKAGYISN
                     PNKVYLVLDSDKTTLTDIRQTMKKYPYDFIVFDRRTGKIVASRYQKNDKDNYYLAKVKN
                     KSYINGTTSYTISSNKLYSLVIRQNSVPEFTNPVLRKFSYNQISYIFLIIYESLIIIIA
                     IYKLIHEISKNFTAIQKIALNMGNKVTKDYPKSKIKEFDTVLKQLYQKSDELSTLIETE
                     RIEKEDLSFQVAVLSHDIKTPLTVLKGNIELLELTNPDKRQLEFMESMKNSIQTLENYF
                     NTMINYTKLLNLNSISEEIDLNEFIKELFLELTDIAIVNKTNNRLKVKTNLKKFHANVP
                     ALKRALINIFLNACQYADKSNPQVSVTVTEDLKFLWFEIWNNGAPFSEEAQVNAQKLFF
                     TEDKGRSGKHYGIGLSFAQAVAVRHGGTMIITNLVNDGVSVKLGIQKF"
     CDS             15031..15711
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 176.8; E-value:
                     9.2e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_15"
                     /transl_table=11
                     /translation="MKIEVKNISKKYQNREVLKDVSFTIEKGTICGLFGMNGVGKSTLM
                     KIIYGIEIPDKGQVLFEGHGKTSNIGALIEQPPIYSNLSAFDNLKTKALLYDIPNNQIK
                     DVLKRVGLDSTDKKHAGKFSVGMKQRLGIGMAILTQPKFIILDEPTNGLDPDGVIEFLD
                     LLKSLKKQGVTILISSHQLHEIGRIVDQVIILDKGHVVYNKIQSNYKDIEEIFFNVMKG
                     ESFI"
     CDS             15708..16424
                     /locus_tag="ctg10_16"
                     /transl_table=11
                     /translation="MIKALFSEILKLKKVRINKLLWIIPLLTGLIAFLVGGVIIFSPFA
                     IYWWESVFLYLLIGLLFLMDFNMEKKAGNFQNVKYNLWSFQIYLAKIFLIFIRVAISSL
                     FFIILVIVLNKFFSGYTELLLSKSILSIFLLLLSVFWNIPWLYFLANFINGYLLIAVNT
                     LVCLLFGSIISQTQWWFAFPYSYHYKISQYLLGVQPSGIFKIINLQLFDVMSPVLLSLL
                     ISLLLIYFTRWGKSND"
     CDS             16417..17070
                     /locus_tag="ctg10_17"
                     /transl_table=11
                     /translation="MIRSELLKLKSSPTIYLLVSFTIFEIASAYGYLYWHRNLLTYKNV
                     VLAFALAYPSLISVVTNICFEQEREANNFQEVRKYSQVKLLTIKTLILDLLLWWISFFV
                     WWIISYSIAQVKLGIISGIAMWLLIVLLNHSHMFLYMVTNKYINLVFSLVEILFIIFAS
                     NKTLMSAYWCFVAWPINYLIHADNSKLYFSAMWILILTILDYFIFRSIELERID"
     CDS             17860..18141
                     /locus_tag="ctg10_18"
                     /transl_table=11
                     /translation="MKQMYISINLEKTGANLKRLFKNNGYSVCDIQSVMGFENPQSIYK
                     WLSGRSLPSLDNLVILSKVLHTTIEDILVVDGDVVFLFHLTWTIHLNR"
     CDS             18670..20304
                     /gene_functions="transport (smcogs) SMCOG1068:extracellular
                     solute-binding protein family 5 (Score: 299.4; E-value:
                     9e-91)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_19"
                     /transl_table=11
                     /translation="MKRIKAIITGIFISLTAVLLVACGKSTSENSKQVLNLSTAGPLDT
                     IDISKSTGYGQTGNVFESFYRLGKDGKVTPGLAKSGQVSQDGKTWTFTLRDAKWSNGDK
                     ITAQDFVYSWRRTIDPKTASPYAYLFYDVKNAQAINEGKMSADKLGIKAEGDNKVVITL
                     DRPVSYFKVLMTYPLFGPQNEKVVQKYGKKYGTNSKYMVYSGPFKVKDWNGTSDKWSFV
                     KNNQYWDKKVVKLQKINYQVVKNTNTGYQLFQQGKLDLTPLSSEQVKNLHNKPEFKQYS
                     YSYVAYLDYNFNDSNEVNRKALNNKNIRLALSLAIDRKTLTKKVFGDGSNVPTGFVASD
                     LASNPSTGKDFAEEQKVDNTVDYNEKLAKKYWKKGLQEIGEKNLNFTILASNEMANNDA
                     LTQYLQSQYTKVLPGIKVSVQNIPGNSALSKARKGNYDIYVSGWGGDFKDPITFMQIPV
                     TGTSYNYGKYSNKEYDALIEKAQNEDANDANKRWEDLVKAARIFNADQGVTPLYQQTTS
                     YMQNTKVKGIIQNTAGTQWNYKYAYIK"
     CDS             20566..21345
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 133.1; E-value:
                     2.2e-40)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_20"
                     /transl_table=11
                     /translation="MSVLEVKDLHVTVEGKEILKGVNLKMSTGEIHAIMGPNGTGKSTL
                     SSTIMGDPAYKITKGDILLNGKSIIDLPVDERARMGLFLAMQYPQEIPGVTNAEFVKSA
                     INARRPKDDPIPLMDFIKRLDETLETLDMSEEMADRYLNEGFSGGEKKRNEIMQMMMIR
                     PEFAILDEIDSGLDIDALKVVSRGVNQMRGDNFGSLIITHYQRLLNYIVPDYVHVMMDG
                     QLVKTGGPDLAIRLEKEGYAKLRDELGLDIKLVDENA"
     CDS             21358..22608
                     /locus_tag="ctg10_21"
                     /transl_table=11
                     /translation="MKQLSIDELIELRKEPEWFKAKRKEAKQLIETTKLPSFQKIKYHD
                     WDINVDGTSVIDDQPKFDTNADVYQYASNKAQIKLPPEFLNKGVIVEDFEDALINHEDI
                     MKKYFMEKGLKMDDNRLLAEHVANLQSGVLVYVPKNVDLETPLTCEYIQNSRVEEDYVH
                     HVLIVTEANSSLSYVERLKTDGDKKNTANIVVEVIAGDGSRIHFASVDNLSKNTTAYMN
                     RRGYLQRDSKIDWAMGMMNSGLTIGDFDSDLVGDGSHAELKVVGISTSDQIQGIDTRVT
                     NIGKNTIGHILQHGVALDESELTFNGIGHVMKRSKGSDAQQESRILMLSPQARGDANPI
                     LLIDDNDVTAGHAASIGRVNPEQLYYLMSRGLQKRLAEKLVIRGFLAPVLDEIPLKEIR
                     NEFSELIERKVSYDEEN"
ORIGIN
        1 tttgatagta ggcatatcca attacctcct tcggtggtac tgtttcttac tattattata
       61 cgctatttct cgtcaaaaat caaccatttg ttgtgacaga gcctaaagaa ttgggttatt
      121 tagcactgta ttatcaaatg gaaatagaag atgaaaaaag agggaatcct caatatcata
      181 aagttgcgat tgttggtgaa gtaagtaaaa gtattcaaaa tttgattatt agtaggttaa
      241 atgaaacttt tcaaggaaca actgaagcgg atattttcaa gagtagtgaa agtttcaaga
      301 aatcatctga acgttacttg attgtatttt caactttacc acttgaaagt aaagatgtta
      361 caactccaat tgttagaatt cagagtatct ttaagaatga cgaattagtt agcaaagtaa
      421 ctctatcgca agttatggca ggaattagta gccaacaagt aaaatttaga attcaaagat
      481 ttgaagaaag aatttcctat ttgaaagctg tggagaattt aattgataca gaaatttcaa
      541 caggtgaatt attaccagga tttaagctag attggaagaa aagagaagaa aaaatgagta
      601 atgtcttcca aaatgggatt gcaattccgc atatggttga taaatctaat cattctagaa
      661 tattattgac ggttggcatc ttatcaaaag ctgtaaaata tcaaggaaaa gaagtaagaa
      721 tcattttctt aataggtata ccgcaaaatc taaactctaa attgagtaag attctgtctc
      781 acgtatatga cttaatcttt atgatttcag gatatgatga aatttataat aatttgttgg
      841 aatatgacat ggatttacca ttaacacaga taacggaggg aatatagatg attattttaa
      901 taggattgat tgttgtaggg gcgtttctct tacaaggatt gtttggaatc tttcaaatta
      961 aaaatttttc cagaaattat cgtgaactaa gattactagg accttatcgc attctgattg
     1021 gtaaaaatcc taaacgtttc ttttcaggtt cattgatgtt gatagcgata gataatgatg
     1081 gaaatataaa agaagcccgt ttaatgcaag gggttacagt gtttgctaaa tttagaacat
     1141 tgaagaaact cgaaggcaaa aatatcgcgg ttttagccgc agattatcaa gagttaaaga
     1201 gaatgaataa attgactaga caatgtttat tgaatgctta caaaactttt gttgatttta
     1261 agacacaaaa attgtcagca agtgcttacg atacaagtgt aaatgtgttc aacatgccat
     1321 tatttacgaa gattggttta atggcaaaca atttgaaggt aaatatgtca aagaaattta
     1381 attaggagat gatctcatgg atatagttgt aaatcttgca tcaggtttta tgaacctctt
     1441 tgaaacaggt ggaaaaacat tcattggttg gatgaagaca atcgtaccag ttgtattgct
     1501 attattggtt ttaatgaata caattattgc attcttaggt gaagaaaaga tggataagat
     1561 tgctagagga gcatctaaga acatctttac acgttatcta attttgccat tcttatcagc
     1621 atttatgtta ggtaatccaa tgtcctttac aatggctcgt ttcttacctg aatactacaa
     1681 gccaagttac tacgctgcac aagctcaatt ctgtcataca agtaatgggg tattccctca
     1741 catcaatcca ggtgaattgt ttgtatggat gggtatcgca caaggtgtac aaaaattagg
     1801 tttgaatagt atggacttag ctattagata cttattagta ggtttggtta tgaacttcat
     1861 tggtggttgg gtaactgact ttacaactgc ttatgtatgt cgcacaactg gaattaagtt
     1921 atctaagaca gtggattaat tggaggtaat gaactatgag taaatggaac agtattaaaa
     1981 tcgtaaaagg ctcaggtggt tggggtggtc caatcgttgt aacaccaaca gaagaaaaac
     2041 ataaagtagt ttatgtaaca ggtggtaaca gaccagatat tgttgataca attgttgaat
     2101 taacaggtat ggaagctatt gatgggttta agacagcaat tcctgatgaa gaaatcgcat
     2161 tagcaattgt tgactgtggt ggtactttac gttgtggtat ttacccaagt aaaaatattt
     2221 tgacagtaaa tgttcttcca acaggtaaga gtggtccgtt agctaaatac attactccag
     2281 aattatatgt atctgctgta actccaaaac aaatttcatt agtaaatgct gaagacgcag
     2341 aagcaattgt taagcaacaa aatgaaaagg ctaccaaaga agaaactgca gctgataaag
     2401 aagatggaat agatacttcc aagacattga cacaacaagg tcatggtggc ggatttatcg
     2461 ctaagattgg tattggtgta ggtaaagttg ttgctacatt taaccaagct gctaaggaat
     2521 cagtacaaac agttttgaat acaattattc catttatggc attcgttgct ttgctaatcg
     2581 gtattatcat gggttccggt attggtaact ggttcgctaa aatcatggta cctcttgcag
     2641 ataacgtttg gggcttgatg attttaggtt tcatttgttc attgccattc ttatcaccat
     2701 tacttggacc aggtgctgta atcgcccaag ttatcggtac tctaattggt gttgaaattg
     2761 gtaaaggtca tattcctcca caatatgcgt taccagcatt gttcgctatc aatactcaaa
     2821 atgcttgtga cttcattcct gttggtttag gtcttgaaga agctaagcca gaaacagttg
     2881 aagttggggt tacatctgta ttgtactcac gtttcttaaa cggtttacct cgagtatttg
     2941 tagcatggtt agctagtttc ggattatatt caggaaaata aaagtaaaaa tgaattgatg
     3001 atgaggtgtg atttgttatg ttcttacaaa agaaaaagac taaactttat gaaacagaag
     3061 ttatagaaat tggtgaagaa gctaagaatt tcaaggaaat taaaatggtt atcttatttg
     3121 gtgaaggtgc tccagatgca cttagaccat cttgctacat cattaaagta aacgaattat
     3181 ctggcgaaat aaaggcaggc atgactttac aaattgatga tgaaaaatat aaaataacag
     3241 cagtaggtaa cgaagttcaa actaacttga agaacttagg tcatatagct attaacttca
     3301 caggggataa aactgctaca ttaccaggat cgatgtatgt agaagaaaag gaataccctg
     3361 aaattaatga aggtacaaaa attgctatta taaaataaat tagggaagca tagggagcgt
     3421 tgagggttct ctatgctttt ctagcatgaa aggacaaaat agatatggaa tttttattag
     3481 atacagttga tttgaaaaag attaaatatt actgtgataa attaaatgtt aaaggagtaa
     3541 cttctaatcc aacgattcta aaaaaagatg gagtaggcga tgatttattc gcacatctaa
     3601 aaaaaataaa ggaaattatt ggagatgaaa gagaactcca cgtacaagtt gtagcacctt
     3661 ctgtatctgg aatgatagat gaagctcaca aaattataga tgaagtaggc aaggatgtat
     3721 atattaaagt tccaaccact ttagatgggt tagaagtcat gaaaaaacta aaggctgaag
     3781 gaattagagt aacagcaact gcaatttata cggaatttca aggttatcaa gcaattaatg
     3841 ttggtgctga ctacttggct ccttactata atagaatgtt aaatcaaaat attgattcag
     3901 ctgaggttat tagaaatcta gctaaaagaa ttaacttaga taatagtaat actaaaattt
     3961 tagctgcaag tttccataat gtagcacaag taaatgaagc attaagcaat ggtgctcaag
     4021 ctgtaacagt tggtcctgat attgtggcat ctgcttttaa gatgccatct atttctcaag
     4081 ctgtagcaga ttttagaaat gactgggaaa gtctatatgg tgacaaaaat ataaataact
     4141 tatagtaagt ataataaaaa acctctgaga tagattctca gaggttttta ttaacattaa
     4201 actaattagt ttacacgtgt tgaagcatcg ccagtttcca atacttccaa agtagcattt
     4261 aaaccacctt caactaagtt tctaacagct tcatcagtgt agtaagctac gtgtggtgag
     4321 tagataatct tatcagattc gagtactttc ttgaatgttt cgtcttcaat atcttttcca
     4381 gttaggtcaa taggaactaa tggaccttcg tgttcgtaaa cgtcaagacc agctccagcc
     4441 aaaaggccat catctaaagc tttcaataaa tcttctgtat caattaaagc accacgagcc
     4501 atgttaacta atacagcgtc agatttgaat ttcttgaaca tttcgtagtt aaacatgtga
     4561 tggttttcct tgaaagcagg catatgtaaa gaaataatgt ctgcatcgcg gatagcatct
     4621 tctacggaat cacgatattc taagataccg tctaatttgt cactaggata taaatcatag
     4681 ccgacaactt tagcaccaaa accatggaag attttagcta catggtaacc aatacgacca
     4741 gttccgataa cagcaactgt catatcgccg ataacacgac ctctgatttc aggttcccat
     4801 gagaaattat gttctttaac acgtttttca attaatggga atttacgtat taagttcaat
     4861 gctgtagtta cagtgtattc agcaattgat tctggggagt agctaggtac gttagtaata
     4921 ataatgccat tttctttagc agcatctaaa ttgtacatat cataaccagc actacgttgt
     4981 gcgatttgtt tgataccaaa ttctttcaat ttaggatata agtcatctgt aacttctgct
     5041 acttgcatta aagttagacc gtcaaaaccc ttaacttcat cgatagtatc agatgtaagg
     5101 atgtcactag tcatatcaat tttaacgttg tgttcctttg cccagttttc agccattgga
     5161 cgttcttcat cacgaacacc aaacattttg attgaaacca taaaaaatac ctccttgtgt
     5221 gtatgataac ctttacaata tatagtatac catttattat aacagaatac ttaaatataa
     5281 aggttaaatt taattaattt tttacacttt cttctaatga agtaaagaaa ctaaagaaaa
     5341 atatatttac attgctcaca acgtcactta taatatatgt atattttaca taaagaaggt
     5401 gacgaatttg gaaacaacaa agattacacc caaagttttc attgatcgtg ttttaggcgg
     5461 tactgccatc ggaattatag ttggtttaat tcctaatgct gttcttgccg ctatccttaa
     5521 aatgttcggc actaatcctt ttgccgtgca tctaggacaa gcagcaatta ttttccaatt
     5581 aggaacacct ttaattattg gtacattgat tgctcaaaag tttggctttg atggcatgaa
     5641 gatgaccgta gttggtggag ccgcatttgt aggttctggc gtaattaaat acttcccagc
     5701 gttgaataaa acaggtgcct atgtaggtgc tggaacaggt gatattatta atactatgtt
     5761 aacagcatcg attgcagttg gattaattct gttgataggc gataaatttg gatcagtagc
     5821 aattgtttta acaccaattg tagtaggagc aggtgctggc ttaattggat tctatatgta
     5881 tccatatgtt acagcgataa cttccgcaat tggtaatgtg attaacacat ttacagaatt
     5941 acaaccagtt ttaatgtgta ttttaattgc ctgctctttt gcagtgttaa ttatctctcc
     6001 aatttcaaca gtagcgattg cgatggctat ccaagttaac ggtttagctg ctggtgctgc
     6061 tgcaatggga gttgctgcaa caacacttgt acttgtagta aactcatgga aagttaacaa
     6121 gccaggggta acaatcgcga ttgccttagg tgcgatgaag atgatgatgc ctaacttatt
     6181 tagacgtcca attatcttag taccatgttt ctttacagca ataatttctg cagttcctgt
     6241 agctttgatg tcaatttcag gttctcctgc ttccggtggt tttggtttag taggtttagt
     6301 aggaccatta gcatcaattg aaaaaggctt aggcgttgtc gcagcattgc tagcatggtt
     6361 agttattcca gttattgcgt cacttgttgg tcaattctta tttgaaaaag tatttaagct
     6421 atatgaccgc aaagatgttt ttgaattttt aggttagaaa atattagaat tgaatataat
     6481 tagaaatagt ttaagttaag aaaatgctga aggttacatt actgaaatgt taatctttgg
     6541 cattttttat tttaaagatt tttgccatga ttttaaaatt atcagtttaa ataatatgta
     6601 ttctgaacaa aatctgaaaa taataacata ttatagtgac gttctagaac aaacaattaa
     6661 agggttatta ggaggttttc taaatgagtg ttaatgattt taaattggat ttagtaaaag
     6721 tatcaaagga aagtacaaat tcaaattatt cagttaaaat tacaagctac tcactttgta
     6781 ccccaggttg caaaacaggt gcactaatgg gatgtacaat gaaaactgca tcatgtggtt
     6841 gtcatgtaca tataagtaaa tagtaagaaa gtaagggata gcgtagatca atttgatgat
     6901 ttgctatcct atttttttaa taggtgaaag gggcttgtaa aatgaataat ttcaatgtta
     6961 gtgatgtaat gatacgtaat acaattcaaa catatgaaaa aagtcaaaat ttcaataatt
     7021 ataaggaatt tattgaaatt attaaaaatg atgatatttt tcttgaacaa atattattgg
     7081 ctaatcctaa gctgtatgga atgcttaaaa agtataatgc aggaaaacta aagaaaaaga
     7141 aagaaaaaaa tttttttgaa tcaatatata aatattataa aaggagctat tatcgagcaa
     7201 ctccttttgg actatttagt gaaacttcta atggtaaatt tgccgttaag ggtgataaga
     7261 aaggactagg gaaaacacac aaagtagttt ttatagatat taaatggtta acagatgtaa
     7321 tttttaaatt agaaaaggac tatcaatcaa acttatcttt catatctaat aatggaaatt
     7381 acattagtgg aaatcgtgtt atgcaattat attcaataaa tgatcaaaat ttagaggaag
     7441 ttagtattaa taactctaaa gtttatcaaa ttatatcaga agagtgtagc caaacttata
     7501 agacatatag tgaaatcata gaaaaggtta taacaatata tggtaatgaa tacttaaatt
     7561 taacaaaaga atatattaat gatttagtag agaatcatta tctaatatca aatttacaag
     7621 aaaatatact aattaatttt tctatgtcag acttcataat gaaagttaag gaaatagata
     7681 ttagtaaaaa atatgtagaa atattaacaa agatacaaga gttaattgaa gaatatacac
     7741 atattgaaat aggttcgggt tctgataaat taattgaaat atatcaccaa atggctagac
     7801 ttaataaaag tgataattat attcaagtag atttatataa tgatggaaat atatatattg
     7861 ataatagtaa taaacaaaga atagagaaat tttcaaattt tataactaat actgttaaat
     7921 cagtaactag gacttatttt gatgactata aagataaatt cattgaaaaa tatggtattg
     7981 atcaaggtgt gcagttaata gaactatttg atccaataaa aggaattggc gcaccgtatg
     8041 attatacgca tcctcagaat gaagtttttg aattagagcc tccaacatca tattattccc
     8101 atgatgaaaa agaaatgtat attaataaat atatagaagc tttattaaat agagaagaaa
     8161 ttaatttgaa atgcttttct aattattatg gaaatctgaa ttccaaagaa agtacctcaa
     8221 tacaaggaat agaattattt tttcatatag tccaaattaa taagaaaaaa actctagcat
     8281 taagcaatat tataggcagt aataatatag ggggatcctc tggaaggttc tcattattat
     8341 cagataaatt aagggattat cacatgaaga cacttaaaca agtgaaagtt gcaaatattg
     8401 aagaaggggt gacgtcttgt gaaatagttt ttcttcctga aaatatacga cacgctaata
     8461 taatgcgaac atcttttgta agagaaaaag tccttcctat tttctcaagt actgatcaat
     8521 ctgaagtaag gctaactaat atttatattg gattagatga aaatgaaaat ttttatgcgt
     8581 atgatgtgtc tactcaagaa aaaatgaagt tttatgtaac aagcatgtat aacaagacat
     8641 tatttagtaa tgaactaaga tttttatgtg aaatttcaat aaataataat tttggatatg
     8701 taccatggga tttaatctat aaagatatga attttattcc acgaatcatg tttgaggata
     8761 tagtagtcag tcctaagaca tggagaatat ttaaatttga attaagtaat atagcaatag
     8821 agtcgattat aaagcagaga aatataccga atgaaattta tattgttgac ggtgataaca
     8881 aactatatat taatcgtaaa aattcacttg atgttgaact gtttatgtca gaaataaaaa
     8941 gaaatataga aaagaatggt tatgccatta tacaagaata ttttaataat aaagacatga
     9001 tatataaaga taatgaagga aaaatatcag agatagtggt tccagttatt aatagtaaat
     9061 tcgatgttaa aaaagtaaac aaggaaaaac aacagagaat ctccaaacat gttcgagaga
     9121 aattgccatt caatgattgg ttatatctaa aagtgtatat gtcgactagg agacaagaag
     9181 agtttatacg agtttacata cctctgattc aaaaaaaggt agaaaaatta gacggaaaac
     9241 tatttttctt acgttatatg gatccagtgc cacaaataag gataaggata agtggtaata
     9301 atttatataa aatatatgaa attattaaaa aagatttgga gaaaggtcat agaaatggta
     9361 ttttatcgac ttttgatatt tctacatatg atcgcgaaat tgagagatat ggaggagtta
     9421 atgcaataga tatagctgaa aatattttct gtgaagattc taaacttgta ataaagtatt
     9481 tgaaatttat aaaagaaaag aacatggaag ataaacttga tgatattgca gttgcaatga
     9541 tttattttta tttaaaaata ttttataaaa caaatgaaga cattttatgt tttctagata
     9601 aagtctgtcc caataaggta gataaaaatg taaggtctaa aatacaatac tataaaagtg
     9661 tagtatttaa tcagttaact gacatatatg agattgacaa atacaacttt aataggctta
     9721 aagaagagat tataaaacta aaattaataa ttgataaaaa aaatgctgac actattatgg
     9781 atagtattat acatgtacat aataataggt tatttggaat taatagggtt agggaacaaa
     9841 atctgtattt tattgtaaaa aaaattatta tgtctgaaaa atatattttg aaagggaaat
     9901 aatgatggat gaaataaaaa aactaacatc aaaaaatttt tttaagacat tattaacact
     9961 tccagatacg attaagttaa tttttcaatt agaaagaaaa tatgcaacat acttaatgtg
    10021 cttaaatata gtaacggcat tgattccact attaaattta atagtttatc aaaatctgat
    10081 caatagtata tttagtcgag gaatgcagct tgtatataat attatttatt ttttaatact
    10141 acaaatattt acggtaatat tatctcaact agaagattat ataaacggaa aatttaatat
    10201 gtggctttct tacaatatta atttaaaatt gataaaaaaa acaacctcct taaagttgac
    10261 agattatgaa caatcagata tgtataatct tattgagaaa ataacacagg atagtacgta
    10321 taaaccattt caacttttta atgctgttat tgctatgctg gctgctttta tatctttact
    10381 gactagtttg atttttgttg cggcgtggaa catatggata ggattgctgt tattagtaac
    10441 tcctatgtta tctttaatta tatttttaaa agtaggtcaa cttgaatttt taatacaatg
    10501 gaaaagagcg agtgcagaaa gaaagtcgtg gtatatagtt tatttattga cacatgactt
    10561 ttcttttaag gaaattaaat taaataattt aagtgattat tttgtggaag agtataagaa
    10621 attaaaaaaa gattttatat tacaagattt gcttattgct agaaagaaag catattttaa
    10681 ttcgggactt caaattttat tagactttat caatattttt gttatatgca ctattatagt
    10741 atctgtacaa gctggaagaa tattaatagg aaatttagtt agtcttatgc aagcaactac
    10801 aaagataaat ggctattcac aaacaattat acagaatatt tatattattt ataatactag
    10861 tttgtttatg gagcaattac ttaatttttt gaaaatagaa aatcaaagtg attatcgtaa
    10921 aaacataggg ataggtgatg agaacagaat aaaaaggata gatctaatag atgttgaata
    10981 taagtatcct aactcttctg tcaatgcttt agaaaaaata aacttttcta tgcatacagg
    11041 ggaactaatt gcgataatag gggaaaatgg atctggtaaa agtactctag taaagttaat
    11101 ctcagggtta tacacaccat ctaaaggtca tatatattat aacggtattg aagataagca
    11161 tatatcgaca gatttttacc aaaagaatat atcgatatta ttccaagatt ttgttaaata
    11221 tgagctaact ttaagggaaa atattggtct tggcaatatt gcagagaagt gggatgataa
    11281 taagattata catattatgg ataaattaag gttaaatttt ttaaaagaga atggagaata
    11341 taatttaaat ttacaattag gaacttggtt ccaaaatggg aggcaattat caggtggtca
    11401 gtggcaaaaa atagctttgg ctagagcttt ttttaaaaat gcttctgtat atatattaga
    11461 tgaaccaagt gcagcgctag atccaatttc agaaaaagaa atatttgatt attttgtaaa
    11521 tctatccaaa gataatatat ctatttttat ctcacatgat ttaaatgtag ctcgtaaggc
    11581 atcaaaaata attgttatga ataaaggaag agtagtaggt attggaactc atgaagaact
    11641 tttaaaagat tgtagtttct atcaagaact atattgggca gaaaaatatg gaagaaataa
    11701 aaagaaaaat tttaaaaaat aaatttagta gagtgatatt agaatgggac aggagaattg
    11761 aacagaatgc ttatcgatac aatttcgaag aatttacgct ttcttcggga ttaccagggg
    11821 ttattttact gttattagag atggaagatt tagatagggc atataagttc aaaattgatc
    11881 agtattgtga ctatttatat ggaaagttat caaaatatgg acttttaaca ggttctctat
    11941 attcaggtgc agctggaatt gcattaagtt tattaccact taaaaaagat ttgagatttc
    12001 aaaatttaat tgcaagtcta aatgattaca ttagttatta tgtagacaaa gaaattggag
    12061 agtttaatat tgaaaatgtt actccaccta attatgatgt gattgaagga ttatcaggaa
    12121 ttctcatgta tctgctttta atagataata tagatatcaa attagtgaca aaaattatta
    12181 tttttttatt aaccttatta gatgataatg attcattgat agcgatgtat attaaaacag
    12241 gtaaccaaat gtcagaggca gaaaacgaaa tttatcctaa tggttgtcta aatacaggta
    12301 tgtcacatgg acttgctggt gtaggaagtg tattggctta tgcgtataaa aaaggcttta
    12361 tgaaaaagga aatattgcac ggattagaaa ggattattca gatttatgaa aaatttgaat
    12421 tagttgataa gaataaattt cattggaaag atggaataga ttataatgaa ttggttaata
    12481 atagaacaat tttaaaagat aatgatttat ttataagaga cgcatggtgt tacggtagtc
    12541 caggaataag tgttttatat ttatatattg gactaattca agataattcg taccttataa
    12601 aaaaagcaat agaaatacta tatagagcta ctaaggaaat gcggaatgta gattccaaca
    12661 tgatttgtca tggcaagtca gggatagttt cgatatgcat tttatttaga aaacttataa
    12721 aaacaagaaa atttgataca tttataaata attatactga tgaaatagaa agtatttttg
    12781 acaaagatat tcgaaattta ggctttcttg agggaacaac gggtattatt ttaactttaa
    12841 atgagtgttt ttcaaataaa gggaaaacgc aatggatgaa atcattaatg ttatttgatg
    12901 atttttagct gtagttataa aaattattat aaggaagatg acgtatgtat agaatcttag
    12961 ttatagatga tgatgtagaa attttgaaac ttatgaaaac agcattagaa atgaaaaatt
    13021 atgaggttgt aacttgccaa aatgttcatg ttccgttaaa attatcagat tttgagggtt
    13081 ttaatttaat tttattagat attatgatgt caaagatatc aggaactgaa atttgttatc
    13141 agattcgttc taagatttca acgccaatta tttttataag tgctaaagat gatgaagaag
    13201 atattttata tggtttaaaa attggtggtg atgattatat aaccaaacct tttagtttga
    13261 aacagttatt agctaaaatt gatgcaaata ttaaacgaga agaacgtagt cgtcaagcag
    13321 ttcaggattt cgcagaagtt aagcgtgata tggggaaaat aactttttat ttggaagaac
    13381 gaagggtatg cgttaatagt caagatattc ctttgactag tcgtgaatat gatattttag
    13441 aattgctctc acgaagggct tctcatattt atagtcgtga agacatttat aataatgtat
    13501 atgacgaata tgcagaaact ttatttggat ctatttctga atatatatat caaatccgaa
    13561 caaagtttgc accatttaag ttaaatcctg ttcaaacaat tcgtggtgtg gggtataagt
    13621 ggtatgaaga ataaaataca ttctatgaag tggcgaatat ggaaaacagc ttttgagatt
    13681 tttattgaaa cttttttagg tttaggtttg ttattagcaa taacttttat cttgcagaag
    13741 gcaggatata tatcaaatcc gaataaagtt tatttagtat tagattctga taaaactact
    13801 ttgacagata ttaggcaaac gatgaaaaaa tatccttatg actttattgt attcgataga
    13861 agaacaggaa aaattgtagc aagtagatat caaaaaaatg ataaagataa ttactactta
    13921 gctaaagtaa agaataaaag ttatataaat gggactacaa gctatactat atcttctaat
    13981 aagttatata gcttagtgat tagacaaaat agtgttccgg aatttactaa tccagtcttg
    14041 agaaagtttt cgtataatca aatatcatat atatttttga ttatatacga atcattaata
    14101 atcattattg caatttataa actaattcat gagatttcaa aaaattttac agctattcaa
    14161 aagattgctt taaatatggg aaataaggtt actaaagatt atcctaagtc gaaaattaaa
    14221 gaatttgata ctgtattaaa gcaactctat caaaaaagtg atgagttatc aaccttaatt
    14281 gagactgaac ggatagaaaa agaagattta tcatttcagg tagcagtatt atctcatgat
    14341 ataaaaacac cacttactgt attaaaagga aatatagagt tgttggaact gactaatcct
    14401 gataagagac aattagaatt tatggaatct atgaaaaaca gtattcaaac tttagaaaat
    14461 tattttaata caatgattaa ttatactaag ttactaaatt taaattcaat aagcgaagaa
    14521 atagatctaa atgaatttat taaagaactt tttcttgaac taacagatat tgccatagtc
    14581 aacaaaacga ataatcgatt aaaggtaaaa actaatttaa agaaatttca tgctaatgtt
    14641 ccagctctaa aacgagcgct aatcaacatt tttcttaatg cgtgtcagta tgcggataaa
    14701 agtaatcccc aagtatcggt tactgtaact gaagatttaa aatttttatg gtttgaaata
    14761 tggaataatg gggcaccatt ttcagaagaa gcacaagtta atgcgcaaaa gttatttttt
    14821 actgaagata aaggccgtag tggaaagcat tatggaattg gactatcttt tgcacaagcg
    14881 gttgcagtca gacatggtgg taccatgata attacaaatc tagtaaatga tggagtgagt
    14941 gtaaagttag gaatccagaa attctgatct aattatgaat ttaattactt atactattac
    15001 cgaataatta aagataaggt gatatataag atgaaaattg aagtgaaaaa tatttctaag
    15061 aaatatcaga atagagaagt attaaaggat gtaagcttta ctattgaaaa agggactatt
    15121 tgtggtttat ttgggatgaa tggtgttggg aaatcaactt taatgaaaat tatttatggg
    15181 attgaaatac cagataaagg acaagtacta tttgaaggtc acggaaaaac tagtaacatt
    15241 ggtgctttga ttgaacaacc accaatttat tcgaatttat cagcttttga taatttaaaa
    15301 actaaagcac ttttatatga tattccaaat aatcaaatta aagatgtttt aaaaagagtt
    15361 ggtttagata gtacggataa aaaacatgca ggtaaatttt cagttggcat gaaacaaaga
    15421 ttggggatcg gaatggctat tttaacacaa cctaaattta taattctcga tgaaccaact
    15481 aacggattag atcctgatgg ggttattgaa tttttagatt tactaaagtc attaaaaaaa
    15541 caaggtgtaa ctattttgat atcaagtcat cagctacatg aaattggaag aatcgtcgat
    15601 caagttatca ttttagataa aggacatgtt gtatataata aaattcaaag taattataaa
    15661 gatattgaag agattttctt taatgttatg aagggagaga gtttcatatg ataaaagctt
    15721 tgttttctga aatattgaaa ttaaaaaaag ttagaataaa caaactttta tggatcatcc
    15781 ctttattaac gggtttaatt gcttttttag tagggggagt aattattttt tctccttttg
    15841 ccatatattg gtgggaatct gtttttttat acctactaat aggattatta tttttaatgg
    15901 attttaatat ggagaaaaaa gcaggaaact ttcaaaatgt taagtataat ttatggagtt
    15961 tccaaattta tttggcaaaa attttcttaa tctttatacg agttgcaata tcaagtcttt
    16021 tttttataat actagtaatt gtcttaaata agttttttag tggttataca gaattattac
    16081 taagtaaaag tatactaagt atatttctgt tattgttatc tgtattttgg aatataccgt
    16141 ggttatattt tttagctaat tttataaatg gctatttgct tatagcagtt aatacgttag
    16201 tatgtttatt atttggatct atcatttctc aaacacaatg gtggtttgca tttccatact
    16261 cgtaccatta taaaatatca cagtatctat taggggtaca gccctcagga atttttaaaa
    16321 ttataaattt acaacttttt gatgttatga gtcctgtatt actttcatta ttgatatctt
    16381 tacttttaat atattttaca agatggggta aatcaaatga ttagaagtga attattaaaa
    16441 ttaaaaagta gtcctactat atatctatta gtaagtttca ctatttttga aattgcatca
    16501 gcctacggat atttgtattg gcatcgaaat ttactaactt ataaaaatgt tgtactggca
    16561 tttgctctag cttatccatc tttaatttct gtggtaacta atatatgctt tgaacaagaa
    16621 agagaagcaa ataattttca agaagttcgt aagtatagtc aagtgaaatt acttacaata
    16681 aaaacgttaa tcttagactt attattatgg tggatttcat tttttgtatg gtggataata
    16741 agttattcca tagcccaagt taaattaggg ataatcagcg gaatagcaat gtggctatta
    16801 atagtattac ttaatcatag tcacatgttt ttatatatgg ttactaataa atatataaat
    16861 ttagtatttt cattagtaga gattttattt attatttttg ctagtaataa aactttaatg
    16921 tcagcctatt ggtgtttcgt agcatggcct attaactatt tgattcatgc agataatagt
    16981 aaactttatt ttagtgcaat gtggattttg atattaacaa ttttagatta tttcatcttt
    17041 agaagtatag aattagaaag aatagactga tatttttggg tgatgaaaag ctaattttga
    17101 atattagaca caggagaaat tctaaaattt atgcaaataa agcgatatca aagtttattt
    17161 tgcataaatt aagaaattgg tcctatgtcg aaatcgcaaa aattaaccta acagtttata
    17221 gtttaatgac ctaagctttg ttagtatata agtgtaccga tgaagctagt ggataaggtg
    17281 tgacaagccg cctagccata catctcttaa taactactat gacgaaatat acggatacgt
    17341 ttattttttc taatttccac ttgggtagta ctaattggga gcaacgaaaa aaagttgtgt
    17401 agagagaagc aaggggactc gtatctgaaa ctaagacact taccgtcagg gattcgtaat
    17461 atgccatctt cagttaatta aggctgatta ccttaggaac taaagaagaa tatcaattaa
    17521 gaattcgtgt cgtgaagttg tagcgatgca attataactg acgagtaagg tttgagtagc
    17581 caaaatcgac aatcttacat taaattggac attacacatg tttggtgaaa gttggatagg
    17641 aaaaggtcta tgccctgaac ttgaaatgcg gactaggtca tggaagttgc tagccatgat
    17701 gtgctagttt gattcagtag tctaataagt ccagatacaa gagtatccca cgtaaaccaa
    17761 tacgcgtcgg tttacataat ttttagtcaa tgcaaatttt gcgttggcta tttttggtat
    17821 aagtgttaga ggtatgtata attaaattga ggtgattaca tgaagcaaat gtatatttcg
    17881 ataaatttag aaaaaactgg tgctaaccta aaaagattat tcaaaaacaa tgggtacagt
    17941 gtatgtgaca ttcaatcagt tatgggattt gaaaacccac aatccattta taagtggtta
    18001 tctggtagat cactacctag tttggataac ttagtcattc tcagtaaggt tctacatacc
    18061 acaatcgaag acatcctcgt tgttgacggg gatgttgttt ttttattcca tttaacttgg
    18121 accatacatt taaatagata ataattgaaa ggaaacatat agaataaatc attatatttt
    18181 agaaatgata gatgatttaa atgattctaa attggaacga gcaagaaatt tagctgaatt
    18241 agagagttta ttaaataagt aatattattt ttgccaaaaa ttagaaaatg caaacttata
    18301 attaaaattt attgacaaaa gtatagtaag gttatatgat ttggttaaag aaatgagagg
    18361 agtgtgaatc actatgtcaa actttatcaa tacacaatgc tgttgtttgg taacatgttg
    18421 tccagtaggc aacatgaatt ttggtatgca gaaaattaga ttcacacttc caagattgga
    18481 ttaaactgta tatatttatt atcggtaccg atgcagatta atttaatcag ttagattata
    18541 tgagataata ataactggac ttgcgattct aattttttgg agttgcaagt cctttttgtt
    18601 tatctggaag gatggatgat gaactgttta tagattaaaa acatatctta cataaaggag
    18661 aaaataaaga tgaaaagaat taaagcaatt attactggaa tatttataag tttaaccgca
    18721 gttttgttag ttgcatgtgg aaaatctact agtgaaaatt ctaaacaagt tttaaattta
    18781 agtacagctg gaccattaga tactattgat atttctaagt ctactggtta tggtcaaaca
    18841 ggaaatgttt ttgaaagctt ttatcgacta ggtaaagatg gtaaggtaac ccctggacta
    18901 gctaagagtg gtcaggtttc acaagatggc aaaacatgga cttttacttt gagagatgca
    18961 aagtggagta acggtgataa gattactgct caagattttg tatattcctg gagaagaaca
    19021 attgatccca agacagcttc gccatatgct tatttgttct atgatgtaaa gaatgctcaa
    19081 gctattaatg aaggtaaaat gtcagctgac aagttaggaa taaaagctga aggtgataat
    19141 aaggttgtta ttacattaga tagacctgta tcatatttta aagtcttaat gacatatcca
    19201 ttgtttggac cgcaaaatga aaaagtggta caaaaatacg gtaaaaaata tggaactaat
    19261 tctaaatata tggtgtattc agggccattt aaggtcaaag attggaatgg tacttcggat
    19321 aaatggtcat ttgtaaagaa caatcaatat tgggataaaa aagtagtgaa actacaaaag
    19381 attaattatc aagtagttaa gaataccaat acaggctatc aattattcca acaaggcaag
    19441 ttagatttaa caccattatc tagtgaacaa gttaagaatt tacataacaa gccagaattc
    19501 aaacaatact cttattctta cgttgcgtat ctagactaca actttaatga ttctaatgaa
    19561 gtaaatcgta aagcactaaa taataaaaat attaggttag ctctatcatt agcaatcgat
    19621 agaaagacac ttacaaagaa agtttttggt gatggctcta atgtaccaac tggatttgta
    19681 gcatccgatt tagcttctaa tccaagcaca ggtaaagatt tcgcagaaga acaaaaagta
    19741 gataatacgg ttgattataa tgaaaaatta gctaagaaat attggaagaa agggttacaa
    19801 gaaattggtg aaaagaattt gaatttcaca attctagctt ctaatgaaat ggctaataat
    19861 gatgctttaa ctcaatatct acaatcacaa tatacaaagg tattgccagg aattaaggtt
    19921 tccgtacaaa atatccctgg aaatagcgca ttatctaaag ctcgtaaagg taactatgat
    19981 atttatgtat caggttgggg tggagacttc aaagatccaa tcacattcat gcaaattcca
    20041 gttacaggaa cttcgtacaa ttatggaaaa tattctaata aagaatatga tgctttaatt
    20101 gaaaaagcgc aaaatgaaga tgccaatgat gctaataagc gttgggaaga tttagtaaaa
    20161 gcagctcgaa tctttaatgc tgatcaaggt gtaacgcctc tatatcaaca aacaacatct
    20221 tatatgcaaa ataccaaagt aaagggtatt attcaaaata ctgcaggtac acaatggaat
    20281 tacaaatacg cttatattaa gtaggtaaaa actcgtctag aatggtttct aggcgagttt
    20341 ttaagttgcg ctaaataatt tgtataagag tattgattat gctgtatgta agcgttattc
    20401 tatatttgta aacttattat aaagattatt acttaattac aaataaattt aagggaatat
    20461 attgtaaaaa tacttaaata caatcgttaa gttaggtaat ttgtcttata atgttattga
    20521 taagaaaatt ccaggaaagg taactatttt atagtggtga tttaaatgtc agtattagaa
    20581 gttaaagatt tacatgtaac tgttgaagga aaggaaattt taaagggcgt taatttaaag
    20641 atgtcaactg gtgaaattca tgcaattatg ggtccgaatg gtactgggaa atcaacactt
    20701 tcttcaacta ttatgggaga tcctgcttac aagattacaa agggagatat tttattgaat
    20761 ggtaaaagta tcattgattt accagttgat gaacgtgcta gaatgggact atttttggca
    20821 atgcaatatc cacaagaaat tccaggagta actaatgcag aatttgttaa gagtgcgatc
    20881 aatgctcgtc gtcccaaaga tgatccgatt cctttaatgg atttcatcaa acgtttagat
    20941 gaaacattag aaacattgga tatgtctgaa gaaatggctg atagatattt aaacgaaggc
    21001 ttttctggtg gtgaaaagaa acgtaatgaa attatgcaga tgatgatgat cagacccgaa
    21061 ttcgcaatat tagatgaaat tgactctgga ctagatattg atgcacttaa agtcgtttct
    21121 cgtggtgtca accaaatgcg tggcgataat tttggatctt tgattattac tcactatcaa
    21181 agactcttga actacatcgt tccagattat gtacatgtta tgatggatgg ccaacttgtc
    21241 aaaactggtg gcccagattt ggcaattcgt ttggaaaaag aaggatacgc aaaacttcgt
    21301 gatgaacttg gtctagatat taaattagtt gatgaaaatg cttagggggc ttgtacaatg
    21361 aaacaattat ccatagatga attaattgaa cttcgaaaag agcccgaatg gtttaaagct
    21421 aagcgaaagg aagccaagca gctaattgaa actactaaat tacctagttt ccaaaagatt
    21481 aagtatcatg actgggatat aaatgttgat gggacgagtg taattgatga tcaacctaaa
    21541 tttgatacta acgctgatgt ctatcaatat gctagtaata aggcacaaat taagttacca
    21601 ccagaatttc ttaataaagg tgtaattgtc gaagactttg aagatgcttt gattaatcat
    21661 gaagacatta tgaagaaata ctttatggaa aaaggattaa aaatggacga taatcgcctg
    21721 ttagcagaac atgtagcaaa tcttcaaagt ggagttttgg tttatgtacc taaaaatgta
    21781 gacttagaaa caccattaac atgcgaatat attcaaaatt cacgagttga ggaagattat
    21841 gttcaccatg tactaattgt tacagaagca aatagttcac tatcttatgt ggaacgttta
    21901 aaaacagatg gtgataagaa aaatacagct aacatcgtag ttgaagttat cgctggtgat
    21961 ggaagtcgaa ttcactttgc tagtgtcgat aatttaagta agaacacaac tgcctatatg
    22021 aatcgtcgcg gatacttaca aagagattcc aagattgact gggcaatggg tatgatgaat
    22081 tctggtttaa caatcggtga ttttgattct gatttagttg gcgatggctc tcatgctgaa
    22141 ttaaaagtcg taggtatttc aacaagtgat caaattcaag gaattgatac acgagttaca
    22201 aatattggaa agaatacaat tggtcatatc ttacaacatg gtgttgcttt agatgaatcc
    22261 gaattaactt tcaacggcat cggacatgta atgaagagaa gtaaaggctc tgatgcacaa
    22321 caagaaagtc gtattttaat gttatctcca caagctagag gggatgctaa tccaattttg
    22381 ctaattgatg ataatgatgt tactgcagga catgcggcaa gtattggtcg tgtaaatcct
    22441 gaacaattat attacttaat gagtcgtggc ttacaaaaac gtttagctga aaaattagta
    22501 attagaggtt tcctagctcc tgttttagat gaaatacctt tgaaagaaat tcgcaatgag
    22561 tttagtgaat tgattgaaag aaaggtaagt tatgatgaag aaaactagtg atttaaggaa
    22621 agattttcct cttttagaaa ctaaaatgaa cgatcagcct ttaacttact tagatagtgc
    22681 agctacttcg caaaagccta agcaagtaat tgacgaaatt gctgactact ataataaata
    22741 caatagtaat attcatcgtg gtgtctacaa tttagcagtc gaaacaactg ataaatatga
    22801 aaatgtaaga cataaagtgg caaattttat taatgcttat cgcgacgagg aagtactttt
    22861 taccaaggga acaactcaaa gtttgaactg gatagcacaa ggttatgt
//
