LOCUS       c00009_JAIQWG0..       13506 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIQWG010000018.1 Streptococcus thermophilus strain DS14_14
            NODE_18_length_36385_cov_160.325213, whole genome shotgun sequence.
ACCESSION   JAIQWG010000018
VERSION     JAIQWG010000018
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:11:13
            Original ID  :: JAIQWG010000018.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 22879
            Orig. end    :: 36385
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13506
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[32879:35039](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12160)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..13506
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13506
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(198..1337)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 86.3; E-value: 5.4e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg9_32"
                     /transl_table=11
                     /translation="MASVLYRKRGDSNLWTYEIRNEGKTVAHNSGFKTKKLAESEAEPI
                     LQELRLGKRISRDISLADLYQEWLELKILPSSRSEETKKKYLLRKNTIERLFGNKKVTQ
                     IRASEYQRIMNKYGQTVGRNFLGRLNTGIHQSIQMAIADKVLIDDFTQHVELFSSKEQQ
                     MTEEKYLHTEKDYLDLLLAVKRKFDYQRSIVPYIVYFLLKTGMRFGELVALTWNEVDFD
                     RGLLKTYRRYNTLSHKFVPPKNKTSIRMVPIDEECIKILRLLQTEQERANMELGIKNRY
                     RMIFQHFGYIHSVPDIASVNKALSVLLNELDIYPIITTKGARHTYGSYLWHKGFDLGVI
                     AKILGHRDISMLVEVYGHTLEEKIFEEFNQIRDIWKDCS"
     CDS             complement(1339..1527)
                     /locus_tag="ctg9_33"
                     /transl_table=11
                     /translation="MDNNLISNKELIEMGYRPHTANDIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVNEILGTEVA"
     CDS             complement(1539..2156)
                     /locus_tag="ctg9_34"
                     /transl_table=11
                     /translation="MYFARLNSLTVRLSRFDLAFDIFNRPEIVNLQHIKGGVTHKVFYG
                     RGGELETKYWGSSGSNVQVRLYDKNKEIIAHKHEEKLDLGVNPFWWRLEFQLRTKAIGE
                     DMVQDIMNRLDNFGFYKLEHIRVDQRAFTIIFLSNPELLSLAFPNLKSDSIKKKKTRVR
                     KLLREETNQFAEELKEVLIQNLPKLNTELQLLVGEFLTLENQ"
     CDS             complement(2160..2513)
                     /locus_tag="ctg9_35"
                     /transl_table=11
                     /translation="LISIQDLRSIQERCEIGELVQRLDVSIDRLTVIWDTDTGPLRRIF
                     KNLKQAISTRVDSFEIHDNVRDDVFTLAKDFNEYDSINIIFFQLSTYGGEQLIRIDFNP
                     NTLKEFDGMKVWR"
     CDS             2925..3047
                     /locus_tag="ctg9_36"
                     /transl_table=11
                     /translation="MTFIIQNFGPNLARLRIEKGVSQTQLAEDLGIGKQSISDY"
     CDS             3078..3437
                     /locus_tag="ctg9_37"
                     /transl_table=11
                     /translation="LDKIAEYFNATPTQLFGTSKEIELEKSVLESNEYSDKVSEILKAV
                     KYIENFLETDGQYLEDLLYLTRGKQLYTEDGDELYTDPTSQKRTFHNQYEPGFIVARDK
                     SPLELLIENKELFDK"
     CDS             complement(3841..5382)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 150.2; E-value:
                     1.4e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg9_38"
                     /transl_table=11
                     /translation="MLRSYVTKKHLTFYFLAIVITWLEAIITPALIQYIVASFTNRQLH
                     LLWQILLWGIGGNLVLVLGLAGKRYYYARLMTDFKVGIKRAIFRTFLYSRQIPDEEVLS
                     DLENDVQQLENSYIEPTVIIVSSLGFTVVSIAYALWTNFYLGLLFIIFYSVPVLCSGLG
                     SKRLDRIAEQKSLANQNYIARVNNMIAGVAPIRHYQGQNLFFKRFSKDLEQALQEEVSY
                     EKQRSLNSLFINSIDAFCSVAPIVIGGFMTYQNYLSAASFVGIYLVSHNIGYQFQELSY
                     FINTRKSAKSLCDKYQDLFGNKLATDSIFDQSVFPIQLEQVSVEKDGETILAPCDLTIH
                     AGEKIAIIGESGAGKTTLLNILYGEIHPSQGQIRYQGRELTSCQLYQAGAYILQSSHVF
                     DDLSVEENIALGQEIDQQRMDNILQETGLLSLKGKVPSNQTLSGGEKQRLEIARALYHK
                     RQFILADEVKANLDAKNQEKINQLLFSLPQAVVEVIHHYTKEDLKRYDKVIHLKK"
     CDS             complement(5375..6370)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_39"
                     /sec_met_domain="Fer4_12 (E-value: 5.1e-09, bitscore: 28.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNRIMDLTTADNIIQEIASKGVTQINRLILFGGEPFLNIELFIY
                     FIEKLSTLLNVVKIETVTNGTVLNKRVKEMLVKFHPYLTISLDGPEIVHDRLRGRGSHR
                     KTLRFINYLKNIDYENFEIASTYTRLHQKNGLSREDIFQYFTDMDVHFNINDVFTKNKV
                     LIVKEMEKSLAERKQFIDKSIQHVINNNEKAFISPILYDVLISMIYKSTNRTFCDDIDP
                     SNTLTYDVDGSKKLCFRFWGTHNSPKAESFNNKDNFEKCKNCWCRGMCLECVANVIDGY
                     SSVISEDGEFLECSKPELMEYCIKQIIYLSKDREKLSRLVNNFRGFIRYA"
     CDS             complement(6630..6737)
                     /locus_tag="ctg9_40"
                     /transl_table=11
                     /translation="MEKLQVIDLEELLEFDQGCVINASCGPSHSCGGGR"
     CDS             complement(6815..7513)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_41"
                     /sec_met_domain="TIGR01716 (E-value: 1.6e-48, bitscore:
                     156.7, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIEEFVYAVRDFRRDDFNELLEKIRYLVSNRDIDGMKKLLISQM
                     EKKDKKEPFASFNTILIKIRLQDLSGETYVTDQEIVTISDYLFSAEYWGYYELLLFMNT
                     IDALNHNTMMILAKEMCHRLDFYRDIPNNRRLLATMLLNAYITCIERNEWMDALYFEKQ
                     LKYCNFSETEMYEKLVLHYANNLYDLKKNNNRHAVLEMRKCIAATKLVDSNQISIKFEN
                     YLQKVLDDMR"
     CDS             complement(8428..9996)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 125; E-value: 6e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg9_42"
                     /transl_table=11
                     /translation="MKKYILKYKLLNLIHIILIGFSSAFLVGASVTLSIMLNKLVESDF
                     KGFLIWLGIEFGVYLLFLADTYLIRVNQTKLIQKMTLSLRDDYINSLTRKSFSEFKNKT
                     VGEHLSILNNDIKIIEESGFESFYSLVSTVFTTFFSIIALFSYDYRIVLLSILLTLILT
                     YLPRSFAHKMEKAMKRFSIGNETFISSLTDQLLGYDTLYYSNKKEMLSIKCGEVIKKFI
                     FEKIVFIKTSSLIEIIMSLFSIISQMLVLLLTGYLIILKQVSIGSISSVGQISGNIFNS
                     LTTFNQLQVSISSVNIIFEKFGAFEKSSHYRYIDKDIEEIKLTNVGYSFKDKEIFKNIN
                     CSFEKGKNYAIVGESGSGKSTLINIILGNNKQYSGSVKYNDVEISDIEESQLFKSVSYI
                     GNITHIYHDSLRNNLTLWDNKINESEIINILKQVNLIDLIPRLDDEVSMSFLSEGQKQR
                     LGIARAYLTKTNVIIMDESMANLDRDNAFLIENQLLNDPTRMYITVSHHLQEKLLDRFH
                     SIITL"
     CDS             complement(10001..12160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_43"
                     /sec_met_domain="LANC_like (E-value: 2.4e-08, bitscore:
                     24.7, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.7e-14, bitscore: 45.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELITPSEKRIINRKKGEIYDYISYSNAFVPYQGWKIHISANLI
                     DYQSILDNVYHVCSIFQTPFKYINKISELFRILSKHVSQLEIGKFITIYPKNKETFLLL
                     LEELYDKIPKYTGVQILTDRSYKDSEIIFYRYGVMNARLINNERPKLKFNGTFYEDITE
                     PYYTCPPFVEDIIFNKVVDDYNIESLFHDRYQMESIIHKSGAGNVYIAIDTINEEKVII
                     KEARKKVYITEKILAIDLLLNEKCILKKLKGKVDIPNYIECFTIEGNLYLVEEFIDGQR
                     LDILKPEYNLLIKRNSSELGRYNKKVKKIISNLFLSLYKIHQEGIILEDISSSNILLTN
                     DDRVFFIDLETAYNKNDGIIVETTNECYPKNISQKNEQRDIVKMWYCIIDLLTNSTSLL
                     KYDNTGVSTLNLFYKMSLENNLPKSLRKKFINDFSIVDFKNTFIIKFIEMGLNIEKIVR
                     MQQDLTETILSHNTFEIYGKTILESIDNYKHISNMDLKFSSDPSFSSLYDNCNKSIDDL
                     IGIAILDNNFELFLNCNLDELLHNMSYYQKYYLLRLFNDTKICDRVYFIKVLNSIIKND
                     IKCIDGVKYIKSNEYFSPYLITGNSGLIIELIKFSKNNNTMKFDEWIRSLSEGISYTYA
                     KGTSLYYGLAGLGLANAWLYYYFKETSFLKTSIKICEHIFDFSIKQNTKTILIDPMSEE
                     IDYTYSKGMLGQLYFINELLNIIKE"
     CDS             complement(12245..13117)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_44"
                     /sec_met_domain="TIGR01716 (E-value: 2.8e-31, bitscore:
                     100.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTIDIGSLTKKIRLSKKLSLKDVAGDYLSVSFLSKFERGESEI
                     SLSRFLCILENLDVSIEEIYGILSKDNPTRTEELLARVSKAFQQNNIPALKKYYYEEIE
                     KFNSTHKKIFLYNSILIDSFLISITGKKMNKKHIEVISDYLFDVDQWGKRELVILGNSM
                     SAVPTNTLNLLIKEIIYKTTLFGNNEENKKIKIDLILNGISIFLERKELNYAKFYIDLF
                     DTLTIPEVYLYERVEYNILIGTYWILIGKIEVGKKKIELALESLKNLGAENLLLMRENE
                     YEELLNSII"
     CDS             complement(13278..13367)
                     /locus_tag="ctg9_45"
                     /transl_table=11
                     /translation="MTTQNLNKLPGTIAVPMDKIRITIYCPSF"
ORIGIN
        1 atacaaactg tggatcatcg gtaccaatac agcatccagc ctccttagct cagttggtag
       61 agcagtggac tcttaatcca tgggtcacag gttcgagccc tgtagggggc atcaaacttc
      121 aacagtaaaa gccttgataa ccaaggcttt tttgcttgtc ttaagagcat ttgccccatc
      181 gtttgcccca cattttttta tgagcaatct ttccagatat ctctgatttg attaaattcc
      241 tcaaaaattt tctcttctaa agtgtgtcca tatacttcta ccaacattga aatatctcta
      301 tgccctagaa tttttgcaat aactccaagg tcaaaccctt tgtgccagag gtagcttcca
      361 taggtgtgac gtgctccttt tgtcgtgata attggataaa tgtccaactc atttaagaga
      421 acactcaaag ctttattgac gcttgcaata tctggaactg aatgaatata tccaaaatgt
      481 tgaaagatca ttcgatatcg atttttgatt cctaactcca tgtttgctct ttcttgctcc
      541 gtttgtaaaa ggcgcaaaat tttgatacac tcttcgtcta ttggaaccat ccgaatagac
      601 gttttatttt ttggtggaac aaacttatga gagagagtat tatacctcct gtatgttttt
      661 aacaatcctc tgtcaaaatc aacctcattc caagttaacg ctactaactc tccaaacctc
      721 atgcctgttt ttaatagaaa atagacgata taaggaacaa ttgaacgttg gtaatcgaat
      781 tttctcttta ctgctaaaag taaatccaga tagtcctttt ctgtatgtaa atatttctct
      841 tctgtcatct gttgttcttt ggatgaaaac aactcgacat gttgtgtaaa atcatctatt
      901 agaactttgt cagcaattgc catttggatg ctctgatgaa tccccgtatt caatctacca
      961 agaaaatttc taccaactgt ttgcccatac ttattcataa ttctttggta ttcactcgca
     1021 cgaatttgag tgactttttt atttccaaat aatctttcaa ttgtgttttt acggagaaga
     1081 tattttttct ttgtttcttc cgacctacta cttggtaaaa tttttagttc aagccattct
     1141 tgatatagat cggcaagaga aatatctcta gaaattcttt ttcctaaacg aagttcttgc
     1201 agaatcggtt cagcttctga ctctgcaagt ttttttgttt taaaaccgct attatgagca
     1261 acagtttttc cttcgttacg aatttcatag gtccataaat tactatctcc tcgctttcgg
     1321 taaagaacac ttgccatatt acgccacctc tgttcctaga atctcattta caacactttt
     1381 tggaacaacc atcaaacgtt tgcgattata aaatgtatag cctcgtgata caagtaattc
     1441 tcttgcctga tggatgatat catttgcagt gtgagggcga tagcccattt caattaattc
     1501 tttgttgcta attaaattat tatccatagt tatcctcctt attgattttc taaagtcaga
     1561 aactcaccta caagtagttg taattctgta tttaatttag ggagattctg tattaatact
     1621 tcttttaatt cttccgcaaa ttgattcgtt tcttctctca atagtttgcg gactcttgtt
     1681 tttttctttt tgatgctgtc tgattttaaa tttggaaaag ctaatgataa cagttcagga
     1741 ttgcttagaa agataattgt aaaggctctt tgatccactc gaatatgttc tagcttataa
     1801 aatccgaaat tatcaagtcg attcataata tcttgcacca tatcctcccc aatcgcttta
     1861 gttctgagtt ggaactctag tctccaccaa aacggattta cacccaaatc tagcttctct
     1921 tcgtgcttat gagcaatgat ttctttattc ttatcatata acctaacttg tacattacta
     1981 ccgctagaac cccaatattt cgtctctaat tcgccccctc taccatagaa gaccttatgg
     2041 gtaacaccac ctttaatatg ttgcaaatta acgatttcag gcctgttgaa aatgtcaaat
     2101 gccaaatcaa aacgagacaa acgtaccgtc aatgaattca atctggcaaa gtacattaat
     2161 tacctccata ctttcattcc atcaaattct tttaaagtgt taggattgaa atcaatccga
     2221 atcaattgtt cacctccata agtggataat tggaaaaata taatattgat tgaatcatac
     2281 tcattaaaat ccttagctaa agtaaagaca tcatctcgca cgttatcatg tatttcaaat
     2341 gagtcaactc ttgtacttat tgcctgtttc agatttttga aaattcgtct taggggacca
     2401 gtgtctgtat cccagataac cgttaatcta tcaatactga catctaacct ctgtactaat
     2461 tctcctattt cacatcgttc ttgaatgctt cttaaatctt gtatagaaat caacaaaatt
     2521 gtcccccctt cttttagatt ttttaggcct cagaaacacc gtcaaatcaa cgtttgctcg
     2581 ttccgtcgtt ctttggacgt tgtcctaagt gtaccttttt gctggctgtt agaatagcca
     2641 gcttttgctt ggctagaaat tgtctggacg gcagcctgca ggacttcgcc tgacttcacg
     2701 tcaggctcgt cccttgccct tgtccacaca atttctagct ccaaggcttc gaatagtcat
     2761 cagtcatagt catagtctcg tcctcaaatt cctcctcact cactattcct aaacatatga
     2821 gctatttgta tcatttaaaa aatattttga gcagtcaact aaaaacttga tttgtaagtt
     2881 tataggtgat agaataagtt taaaatacaa cataggagtt tatcatgacc tttattattc
     2941 agaattttgg acccaatttg gcacgactac gcatagaaaa aggagtaagt caaactcaac
     3001 ttgcggaaga tttaggaatc ggtaaacaat ccatctctga ctactaaaaa caaaaaagct
     3061 atcctacctt tgcaaatttg gataagatag cagaatattt taatgcaact ccaacccaac
     3121 tatttggaac tagtaaagag attgaattag aaaagagtgt tcttgaatcg aatgaatact
     3181 ctgataaagt aagtgagatc ttaaaggctg tcaaatacat cgaaaatttt ctagaaactg
     3241 atggacagta cttagaggat ttactttacc taacaagagg caaacaacta tacacagaag
     3301 atggagacga gttgtatact gatccaactt ctcagaaaag aacatttcat aaccaatatg
     3361 aacctggttt tattgtagca agagacaaat ctccactaga actcttgatt gaaaataagg
     3421 aattatttga taaatagaaa aagcgagttt gaactcgctt tttctgttat gaaagaaata
     3481 acttattttc tagtttttta gataaatcct ctctccaaat atccgtcacg gtcgcttctt
     3541 cccagttctt tgggcttacg caagatttta atcaattttg agttaaaaat aaatactcta
     3601 aatactcatt caattcatta attatttagt caatggttgc tttgtatcca caattccaaa
     3661 tagttctaaa tgagatttta ggaactttga aaactttaaa aaacgcattc ttatcacttt
     3721 gaagataaga aaagagagaa cgaattgtgt cctctctcga tgttagcttt tcatcaactc
     3781 aagacagttg acaaagagcc tttcagatat acaatttgtc tatagacact attggcataa
     3841 ctactttttc aaatgaatca ctttatcata gcgcttcaag tcttccttgg tgtagtggtg
     3901 aatgacctcc accacagctt gaggaagtga aaagagcagc tggttgattt tttcttgatt
     3961 tttggcgtcc aggttagcct tgacctcatc tgctaggata aactgtcgct tgtgatagag
     4021 agcacgggcg atttcaaggc gctgtttttc accgcctgat aaagtttggt tgctgggtac
     4081 cttgcctttt aggctgagga gccctgtttc ttgcaagatg ttatccattc tttgctggtc
     4141 aatttcctgt cccagagcga tgttttcctc cacagataaa tcgtcaaaaa catgactaga
     4201 ttgcaagata taggcaccag cctgatagag ttgacagctg gttagttccc gtccttgata
     4261 acgaatttgc ccctgactag gatggatttc cccgtatagg atgttgagca gggtggtttt
     4321 gcccgctccg ctttctccga tgatagcaat cttttcccca gcgtggatag tcagatcaca
     4381 aggagctaga atggtctccc catccttctc cacactgacc tgctccaact ggataggaaa
     4441 gacagattgg tcaaatatgc tgtcagtagc caacttattt ccaaacaagt cttgatactt
     4501 atcgcagagg gacttggcag acttgcgggt attgataaag taggacagtt cttgaaactg
     4561 gtagccgatg ttgtgggaga ccagataaat gccgacaaaa ctagccgcag aaaggtagtt
     4621 ctggtaggtc atgaatccgc caatcacaat gggcgccaca gagcaaaatg catctatact
     4681 gttgataaat aaactgttca gtgaccgttg cttttcgtag gacacttctt cttgcaacgc
     4741 ctgttctagg tctttagaaa atctcttgaa aaacaaattc tggccctgat aatgacgaat
     4801 aggagcaaca cctgcaatca tattgttgac acgggcgata taattctgat ttgctaggga
     4861 tttttgctcc gcaatcctat ccaaacgctt cgaacccagt ccgctacaca aaactggtac
     4921 cgagtaaaag atgataaaca ataaccccag atagaaattg gtccagaggg catatgcgat
     4981 ggaaacgact gtaaaaccta gcgaggatac gataatgacg gtcggctcta tatagctatt
     5041 ttccaactgt tggacatcat tttccagatc agacagcacc tcctcatcag gaatctgacg
     5101 gctgtataaa aaagtccgaa aaatagcgcg ttttatccca accttaaagt cagtcatcaa
     5161 acgagcatag taatagcgct tcccagccaa gcccaggaca agcaccagat tgcccccaat
     5221 cccccagagc aaaatctgcc agaggagatg caactggcgg ttggtaaaac tagcgacgat
     5281 atactggata agggcagggg tgataatggc ctctaaccaa gtgatgacga tggctagaaa
     5341 atagaaggtg agatgttttt tcgttacata actcctaagc atagcgtata aaccccctaa
     5401 aattatttac caacctagat aatttttctc tgtccttgga taaatatata atctgtttaa
     5461 tacagtattc catcagttct ggtttagagc attcaagaaa ttccccatct tcactaatta
     5521 cagaagaata tccatcaata acattggcaa cacattccaa gcacatacct ctacaccagc
     5581 agtttttaca cttttcaaag ttatctttgt tgttaaatga ttccgcttta ggactgttgt
     5641 gagttcccca aaatctgaaa catagtttct tactaccatc tacatcataa gttaatgtat
     5701 tcgaagggtc aatatcatca caaaatgtac gattcgtact cttgtatatc attgatatta
     5761 atacatcata taaaatagga ctgataaatg ccttctcatt gttgttgatt acatgttgaa
     5821 tggatttatc tatgaactgt tttctttcag ccaaactttt ttccatttct ttcacaatta
     5881 gcactttatt tttagtaaaa acatcattta tattaaaatg cacatccata tcagtaaaat
     5941 attgaaagat atcttctcta cttagaccat ttttttgatg aagtctagta tatgtcgagg
     6001 ctatttcaaa attttcataa tcaatattct ttaaataatt aataaaacgt aatgtttttc
     6061 gatggctccc tcttcctctg agtctatcat gaacaatttc tggtccatct aaacttatgg
     6121 ttaaataagg atgaaattta acaagcattt ctttaacacg cttatttaaa acagtaccat
     6181 tagtaactgt ttcaattttc actacattta ataatgtaga taatttttct ataaaatata
     6241 taaataattc tatatttaaa aaaggttctc ccccgaaaag tatgagacgg ttgatttgtg
     6301 taactccttt acttgctatc tcttggataa tattatcagc agtagttaaa tccataatac
     6361 gattatccat accatagtta ccaccatctg cataacaata cgaacaagat aaattacaac
     6421 tattagaaat atttataact acttttttaa tacaccatct tcaacagaat ctagagttgg
     6481 tgaactttgt tttgaaatag gtgacaaaga taaagtaaaa ttaacagaat caaaataata
     6541 tgttcctata tctgtttcta ttgtctttat cataattatc ctccagacta aaaactgaga
     6601 tgaggaatca ctcctcatct cggaagaagc tatcgaccac cgccacaaga atgacttgga
     6661 ccacagctag cattaattac acacccttga tcaaactcta aaagttcttc aaggtcaatc
     6721 acctgaagtt tttccatggt ttttacctcc tttatttgat agtttcatta tataacctta
     6781 tcagaagagg ataatatttt cccttatacg caattcacct catgtcatct aatacttttt
     6841 gtaaataatt ttcaaatttt atagatattt gattgctatc taccaatttc gtggcagcaa
     6901 tacattttct catttccaaa acagcatgtc gattattatt tttctttaga tcatataaat
     6961 tattagcata atggagcact agtttttcat acatttcagt ctctgaaaag ttacaatatt
     7021 ttagctgttt ttcaaaataa agagcgtcca tccattcatt gcgttcaata caggtgatat
     7081 aagcattgag caacatagtt gccaataaac gtctattatt tggaatatct ctataaaaat
     7141 ccaaacgatg acacatttct ttggctaaaa tcatcattgt gttatgattt aaagcgtcta
     7201 ttgtattcat aaacagtagc aattcataat aaccccagta ttccgcagaa aacaagtaat
     7261 cactgatagt aacaatctct tggtctgtta cataagtttc tcctgataaa tcctgtaatc
     7321 ttattttaat caaaattgtg ttaaatgaag cgaaaggttc ctttttatcc ttcttttcca
     7381 tttggctaat taatagcttt ttcattccgt ctatatcacg atttgatact aaataccgaa
     7441 tcttttctaa aagttcatta aagtcatctc tgcggaaatc acgtacagcg taaacaaatt
     7501 cttcgatagg catatgtatt gcatctaacg ctaaaaaaat tgctgatggt taaatcagcc
     7561 tcatcatttt caaatcttga gagatgggaa cttgaaagac ctgattttgc aacatttttt
     7621 aaagataaac ctcgagattc tctaaatttt ttaaaaattt ttccatattt cattctagtc
     7681 acctcctaaa ttgcttataa gggaaatttc ttcacaaata ttaaaaatat tatatcatat
     7741 aagaaaacga aaagaggtat ttaccatgaa taaaaaagca ttgtttagtt tgttgtttgt
     7801 aatacttgaa ggtattatcg ttatcggagt aggttagcca aatgataaag agattaggca
     7861 agaaacctta aaaataaaaa atagcttaga attgcgtcat tataaacgtt gattccaagc
     7921 tatttttggt tattaaaatt ttaatcagaa gggtaaactt gtagtttttg cccaacctct
     7981 cttgatttta tggaaaaaga atcccgtatt ttggatacga aatgctttca ataagtgtaa
     8041 atcagtttta acgtttacta aatttcgatg ctttacgagc ctttttcaag cctggttttc
     8101 aaagcaagtt ggaaaccttt atgagtcatt cgtttttgcc ccacttttgc cccattttga
     8161 aataattata tttaaaaatg ctccaagtat cttctaaaaa taacttatat ttcaacattt
     8221 ttgattattt tcaatatgaa aaattcatac aaattcatgt agggggcatc atactataca
     8281 taaaaaagcc tttaaataaa ggctttctta cttgtctaaa gaggaaatgt cccatcattt
     8341 gtccccgaaa taatttccaa acttttgata aatattattt ttgtataaat taatttttgt
     8401 tgtgtatagt aacattgaat tctcaattta aagtgtaata atactatgaa atctatctag
     8461 tagtttttcc tgtaagtgat gagagacagt aatgtacatc cttgtaggat cgtttaatag
     8521 ctggttctca attagaaaag cgttatctct atctaaattt gccatagatt catccattat
     8581 tattacgtta gttttagtaa gataggcacg tgcaatacct aatctttgct tttgcccttc
     8641 tgataaaaaa gacatactta cttcatcatc taatcgtgga attaaatcta ttaaattaac
     8701 ttgtttaagg atattgataa tttctgattc atttatttta ttatcccaaa gtgttaaatt
     8761 atttctaaga gaatcatgat aaatatgagt aatatttcct atatatgaaa cgcttttaaa
     8821 caattgagat tcttcaatat cagatatctc tacatcattg tattttacac ttccactata
     8881 ttgcttatta tttcctaaaa ttatatttat taaagttgat tttccactac ctgactctcc
     8941 aactatggca taattttttc ctttttcaaa actacaattt atatttttga aaatttcctt
     9001 atctttgaag gaatacccga cattagttaa cttgatttct tcaatatctt tatcaatata
     9061 tctataatgg gaactcttct caaaagctcc aaatttttca aatataatat ttactgatga
     9121 tattgatacc tgtaattgat taaacgtagt taatgagtta aatatatttc cggaaatttg
     9181 tccgactgat gatattgaac caattgaaac ttgttttaaa atgataagat aacctgttaa
     9241 aagtagtact aacatttgag aaataattga aaataaactc attattattt caattaagct
     9301 actagtttta ataaatacta ttttttcaaa aataaatttt tttattacct ctccacattt
     9361 aattgataac atctcttttt tatttgaata atatagcgta tcatatccca gtaattgatc
     9421 tgttagtgat gaaataaatg tttcattacc tatagaaaat cttttcatag ctttttccat
     9481 cttatgggca aaacttcgtg gaaggtaagt taggatcaaa gtaagtagta tagataaaag
     9541 cactattcta taatcataac taaacagagc aataattgaa aaaaaagttg tgaaaactgt
     9601 tgaaactaat gaataaaaac tttcaaatcc gctttcttcg ataattttta tatcgttatt
     9661 taaaattgac aagtgttctc caacagtctt atttttaaat tcactaaacg attttctagt
     9721 tagactgtta atataatcat ctctgagaga aagagtcatt ttttgaatta atttagtctg
     9781 atttactcta attaagtatg tatctgccaa aaataacaaa taaactccaa attcaatgcc
     9841 taaccatatg aggaagcctt taaaatcact ttcaaccaat ttatttaaca tgattgagag
     9901 tgtgactgat gctccaacta aaaatgcaga actaaatcct attaatatta tatgtataag
     9961 atttagcagt ttatatttta gtatatattt tttcattatg ttattcctta attatattta
    10021 gcaactcatt aataaagtac aactgcccca acattccttt tgaatatgta taatcaattt
    10081 cttcggacat cgggtctatc aatatagttt ttgtattttg tttaatagaa aaatcaaaaa
    10141 tatgttcgca aatcttaata ctcgttttaa gaaatgaagt ttctttaaaa taataataaa
    10201 gccaagcatt tgccaaaccc aatcctgcta atccataata caatgaggtt cccttagcat
    10261 atgtataact aattccttct gataaacttc taatccattc atcgaacttc attgtattgt
    10321 tatttttact gaacttaata agttcaatga ttaacccaga gttaccagtt attaaatatg
    10381 ggctaaaata ctcattggat tttatatatt tcactccatc aatacactta atatcatttt
    10441 tgatgattga atttaggacc tttataaagt agactctatc acatatttta gtgtcattga
    10501 aaagtctgag tagataatat ttttgatagt agctcatatt atgtagtagt tcatctaaat
    10561 tacaatttaa aaaaagttca aaattattat caagtatagc gattccgatt aagtcatcta
    10621 tacttttatt acaattatca taaagagaag agaaactggg atcgctagaa aattttaaat
    10681 ccatattact aatatgttta taattatcaa ttgactctaa tattgttttt ccataaattt
    10741 caaaagtatt atgggaaagt atagtttctg ttaaatcttg ttgcattcta actatttttt
    10801 ctatatttaa acccatttca ataaatttta ttataaatgt attcttaaag tccactatac
    10861 taaaatcatt aataaatttt tttcttaaag atttaggtaa attattctct aaactcattt
    10921 tataaaataa atttaaggta ctcactcctg tattatcata ttttaaaaga ctagtagaat
    10981 tagttaataa atcaattata caataccaca ttttaacaat atctcgctgt tcattttttt
    11041 gagaaatgtt tttgggatag cattcatttg tcgtctcaac aataattcca tcattcttat
    11101 tatatgcggt ttcgagatca ataaaaaata ctctatcatc atttgttaaa agaatattac
    11161 ttgaagatat atcctctaat attattccct cctgatggat tttatataaa cttaaaaata
    11221 gattagaaat tatttttttt acttttttat tatatcttcc taactcgcta gaatttcgtt
    11281 ttatcaacaa attatattca ggctttaaaa tatccaatct ttgtccatca atgaattcct
    11341 caacaagata taaatttccc tcaattgtaa agcactcaat gtaatttgga atatcgactt
    11401 tacctttcaa tttttttaga atacattttt catttaaaag gagatctatt gctaaaatct
    11461 tttctgtaat atatactttt tttctagctt cttttataat aaccttttct tcattaatag
    11521 tatcaatcgc aatatataca ttacctgctc ctgatttatg aataatagat tccatttgat
    11581 atctatcatg gaataaagat tcaatattat agtcatctac aactttatta aatatgatat
    11641 cttcaacaaa tgggggacat gtatagtatg gttccgttat atcttcataa aaggttccat
    11701 taaatttaag ttttggtcgc tcattattaa ttaaacgtgc attcattact ccatatctat
    11761 aaaaaattat ttctgagtct ttataacttc tatctgtcaa aatttgaact ccagtatatt
    11821 tgggtatctt atcatatagt tcttccaata ataataaaaa agtttctttg tttttaggat
    11881 atatagttat aaattttcca atctctaatt gcgaaacgtg ttttgataaa atacggaata
    11941 actcagatat tttattgata tacttaaatg gcgtttgaaa aatagaacaa acatggtaaa
    12001 cattatctaa aatagactga taatctatta aattagcaga tatatgaatt ttccaacctt
    12061 gataaggaac aaaagcattt gaatatgaaa tataatcata tatttcccct ttttttctat
    12121 taatgattct cttttcactt ggtgtaatta gttcttccat gataaatctc ctattaaaaa
    12181 taaaatactg ctgtataact atataactag tgtaacagca gtattttatt tttagtaaaa
    12241 agtgtcatat aatagaattc aataattctt catattcatt ttctctcatt agcagtaaat
    12301 tctcagcacc taaatttttg agggattcca aagctagttc aattttcttc ttgccgactt
    12361 ctattttacc tataagtatc caatatgtac ctattaatat attatattcc actcgctcat
    12421 agagataaac ttcaggaatg gtaagtgtat caaaaagatc aatatagaac ttggcataat
    12481 ttagttcttt cctctctaaa aatattgaga ttccgtttaa aataagatca atttttattt
    12541 ttttattttc ctcattatta ccaaataaag tagtcttata aataatttct tttattaata
    12601 aatttaatgt atttgtaggc accgctgaca tactattacc taatattact aactctcttt
    12661 tcccccattg atctacatcg aaaagataat cagaaataac ttcaatatgt tttttattca
    12721 tttttttacc tgttatcgat attaaaaatg aatcaatcaa aatagaatta tataaaaata
    12781 tttttttgtg tgttgaatta aacttttcta tttcttcata ataatatttt tttagagcag
    12841 gtatgttatt ttgttgaaat gccttactga cccttgctag taattcctca gttcttgtag
    12901 gattatcttt cgataaaatt ccgtaaattt cttcgatact tacatccaaa ttttccaata
    12961 tacaaagaaa acgagaaagt gaaatctcag actcgccacg ttcaaactta gataaaaacg
    13021 aaaccgaaag ataatcacca gcaacatctt ttaatgaaag tttttttgat aatctaattt
    13081 ttttcgttaa agaacctatg tcaatagtat caatcataaa ataactcctt ttatacaatt
    13141 ataacaaaaa acgcaaacat agtgcagtct gcgttaacct tttgaatatt aggagtatat
    13201 tgtaatacga agtctatctt taaattcaaa agaatcactt ggtaaactgt tcaaaatttg
    13261 aataatcatt tttctcctta aaaacttgga cagtaaatcg taatacgaat tttatccatt
    13321 ggaactgcaa ttgttcctgg taacttattt aggttttgag tagtcatttt tttctccttt
    13381 ctaaatctta tagacatatt atatattttt gcaataatta agtattaata ttttcatata
    13441 taggaattgc ccgatactgt caataattat gtgtaaacac tcaagtagag ttgaagaatg
    13501 ttaatc
//
