LOCUS       c00013_JAIQWG0..       15323 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIQWG010000021.1 Streptococcus thermophilus strain DS14_14
            NODE_21_length_24848_cov_171.345622, whole genome shotgun sequence.
ACCESSION   JAIQWG010000021
VERSION     JAIQWG010000021
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:11:13
            Original ID  :: JAIQWG010000021.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15323
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15323
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1269:5323]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1270..5323
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..15323
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15323
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     CDS             complement(2..94)
                     /locus_tag="ctg13_1"
                     /transl_table=11
                     /translation="VNFGVNFINFNKKGSIISVVGKTTVEIIELF"
     CDS             complement(157..330)
                     /locus_tag="ctg13_2"
                     /transl_table=11
                     /translation="MNSVRRRHPELSPASPHKLRHTGATLARKSGVPLEIISEALTHSD
                     KQITKTYVNTKI"
     CDS             474..737
                     /locus_tag="ctg13_3"
                     /transl_table=11
                     /translation="LAHDFASWVSGDSMEPKYHNGSVALIRETGFDYDGAVYAVVCNSQ
                     TYIKRVYLEAEGLRLKYKDIFISYDEDPRVVRIIIGNFIPLK"
     CDS             987..1091
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MENTEFSLELDVTEVSTEQGYVSGGVTSTGCCKD"
     CDS             1270..1548
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_5"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.2e-15, bitscore:
                     45.2, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVANPQFFHNLTKEKIYKNSTFRNYVKRSITRATPFGLFSSIG
                     VGTFSDISYHQKIGENYTKKISVSGEWLSSICMMLENKDSVLLQLHI"
     CDS             1699..4062
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     577.3; E-value: 8.8e-175)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_6"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.7e-65, bitscore:
                     210.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.9e-19, bitscore:
                     59.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLELVLQSKSPDLEKQKILDYIRNLITNEFLFTNLRKVAISHKDL
                     DDLTNILKDINNQRKLTEDLLQIKNSIEQYAKLELGEGISQYTEICKKMSYIFNDKKQH
                     YLKVDLVNCCDSVLPKNLKKKMEDFVNFISKINLAKGYRNRELESFTEKFVEKYGEYVE
                     VPIKELLDGNLGLGLPKQTLGTHVKSSSSVEEQNFLSYLSKEVFKAVKNCKKEIDISNI
                     PLGLLYPNSDRFVANQLELYCEIKNFESQPVISVVPNTGSDMIGKSIGRFASYFPNSYI
                     SLDSQLDNVELIEFPRDSKNLNVMSAQNAHSKKLLLSYDDNDNTSIELDSVVVGVIKTE
                     YRYKLYFRDLRTGSIVNFVTTSMLNHKSNGVFSDLARFLLAVSLEWQDNPFSVFRIIEN
                     FDYLPYIPKIKYGNIILSEEKWVLSDIDKNDLSSIKQWKKDFDVPRLLYFHKADERLLV
                     DLENDLDTQWLLKQNVDKLYFTRFEKYDGKNCEFIFGFENYQSSINHYSMQEKSVRRLT
                     NNFYKNHVKTFSSDWIYFRLYGINSSILLELRERLLLFTDELLVEKLISDFHFVNYSDK
                     DNGSLRLRFKINNDDNFEDLRFRIAHWIDFLLESGFCNDVSFNLYEREIERYGGDNFIT
                     VCERMFSIDSFLTLKLFSKKLLNDKDLFSVLHSTFLYIRLLGIPLKRLLELLKGNLTQN
                     RYRKSFKKLFPNNTIVVKEFKEYFDYKNQFEIFNEVFREFPPIDGYFEGKNDIVYSLLH
                     MHMNRVGMFPYREKEYLYFIMYIAEPLNNYKEFT"
     CDS             4100..5323
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     308; E-value: 1.6e-93)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_7"
                     /sec_met_domain="LANC_like (E-value: 6.3e-52, bitscore:
                     167.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLDSDIIDRLQRAYYTENRSYLSEYPSIIIYLSYRLINCDNKEYS
                     KLLYNRVNYYLQELLKSIKLNSTNNISLCYGFTGYVYALEFLSKNCKGYDKLLDTLETI
                     LLALTKDRLREIKSSNIVKEEYFDVIQGVSSVARYLLSKEESTSEQELLVKEILNYFAD
                     LIINEPTIYVEYMPNEKLRKRFPSGYINLGVAHGILGPLYVLALGFEKFNITKHIPSIE
                     KGLSYYENAFFTNTIGKIIGWNGRVSDYGENEEFRFNISWCYGSLGMARVLYNIAKIID
                     SQKLREMAMDVFTSSIDYLNSSEILNNGICHGRSGIMLLFNLMYLDTGKTQFKAISDNL
                     FKEIINDASNSEYIFVERDIYFRGVTFDEVIDYIDFGLLNGVSGIVITLMAQRTGNAYP
                     LDRMLFMQ"
     CDS             5347..6612
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 96.3; E-value: 3.3e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MRKILKNKLYLKVLVSDLISNFGDTLYFIALMTYVTEIKDSNLAI
                     SIVNISETLPILFTIFFGIIADKTLNKVKMIIKTLWLRVLLYLLVAVAMNFKPSIMIVI
                     IASLVNLVADTLGQFENGLFYPISNRIVKKSDREETMAFRQTVVSVMNIINQSLGAFLI
                     TFFSFSHLAFINALTFAISLLIMLAIKNQINSYYDETISTSKISQFDFKASFSEITSNL
                     KLSINHLFSIGNMKEALLVIPILNGSLAILTPLVVVDLSKDSNLTIINSAITISLLGIS
                     TVSGGILGGTLILISKKFKSLSIGTLLKMNLTTVLLSFVAFYFQNIYLIILSSFLSSVL
                     VSALNPKMGTIIFNNIDETKLATIFGGMVTYFQIGDIVSRLLFSTLVIYLPYGYIALIY
                     IAVVFVAILYTLKSSNHIEREF"
     CDS             6841..7353
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MMFDDRLEIHSPGKLPNIVTVENIKHERFSRNPRIARTLTEFGWV
                     REMNEGVKRIYSEMESYFLHEPKYTEPGNKVVLTLENNILSRHLRVNDKMMKKYDEFND
                     LNDDEKAILHIMYNTGEKMTTALAARITNRGRNFASKLLKSLVNKEILEWHGTSKQDRN
                     QYYTLAE"
     CDS             complement(7690..8004)
                     /locus_tag="ctg13_10"
                     /transl_table=11
                     /translation="LRQTQKQFVFTYNDRSNNINLPLHVDYLNYRMKSVRRRHPELAPA
                     SPHKLRHAGVTLAKQAGYSLEAISEALTHSDKQITKTYVNTKDIVNRTVGDIAFRSLKK
                     "
     CDS             complement(8296..8907)
                     /locus_tag="ctg13_11"
                     /transl_table=11
                     /translation="MSIKKTKNGTYQLRLYIPEDVQAKLGLGKLFERKYKTRREAKEVE
                     LKLSIDIKNAKSGKSHINIKNKGEIIFKKFYEDIWLEPYKAGQTTTTIKPPTKATVFQT
                     ENIFRLHILPILGKYSIEYPNNNKQLILSLLTPKANSYANFKVIRSYVNSVFDWAEELE
                     YIPSNKLRKTITRIKANKKILLKESKREEDLSLDKEELKL"
     CDS             complement(8918..9190)
                     /locus_tag="ctg13_12"
                     /transl_table=11
                     /translation="MLVQLPEEQTQEIQQMIATLIKNEIHHFKEDIGADSTFLNKKQTY
                     NYLGISNNTLDIGIAMGLPYIRIGKSIRFNKKSINQWMTRLEISA"
     CDS             complement(9252..10442)
                     /locus_tag="ctg13_13"
                     /transl_table=11
                     /translation="MIKESFPFDILNLFDTKGTPPFNFSNQYLNPNTKILDFNNATLYE
                     VDFDSLSPDTKAKLQEGAYKIGESRKVEGNLRAVIVDTTDQKNRVEDLTLRKMTNNNEN
                     QVPSDLIAQAQLKQIYNLLLDIKENQDYQIRWERNNSILAPFYSARTKVIEANNSKDFR
                     EKVKSLKDANTLFEESVSAIKSDIISNRDEIIKKISQPTYRQASLQTHADFLLQDIEIM
                     TKIVGMQIYIDLTLNNEGIAHDRLLSFQGSMELVSKQNIPYKTNYLKELAKKLLYVKEL
                     KWIKNNSIPKVSLLELIHNHYSYSKNNRDLFININTKLIEFHQDSNVNLSNTETAKIET
                     EKKMTLKTKKCKTCKKTISSPKTIPICDACRNKGKQLTVVGVALLVFFNKIINKKN"
     CDS             complement(10689..10946)
                     /locus_tag="ctg13_14"
                     /transl_table=11
                     /translation="MGNGGQWMNAPGYQTTHTPTEHSALSFSPGQAGADPTYGHIAFVE
                     QVKSDGSILISESNIKGLGVVSYRTFDAETAKQITYVIGH"
     CDS             complement(10922..11263)
                     /locus_tag="ctg13_15"
                     /transl_table=11
                     /translation="VVLSTRQQMVASTSPIPLALGKGVLKPCKNSIPISMSMEVHQKPL
                     NRRKEKPETEAVSQQGMSHKAIASPKKSIPQATQDCLILGDNVPGLSITEEKKSVLASE
                     SIWEMVANG"
     CDS             complement(11454..11642)
                     /locus_tag="ctg13_16"
                     /transl_table=11
                     /translation="LIEQDHRPVKRHNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTL
                     FGFSVCTEIKVLLGIPA"
     CDS             complement(11648..12142)
                     /locus_tag="ctg13_17"
                     /transl_table=11
                     /translation="MTINHFKGKQFQQDVIIVTVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYHWVQEYGKLLYQIWKKKNKKSFYSWKMDEIYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQTAYAFLERLVKQFDEPKVVVTDKAPSITSAFKKLREYGAFIKGQNIVPLN
                     T"
     CDS             12292..13509
                     /locus_tag="ctg13_18"
                     /transl_table=11
                     /translation="MKQSQAKKHDNTMTNKILMRLIALVLGLLFLEILIIHSKNEQQKS
                     VSNQVQTARIMANGDLLYHDGLYMSALQADGSYDFTENFTYVKPWLKQADLVLGDFEGT
                     INPDYPLSGYPLFNAPQSVTAAISDAGYDVMDLAHNHILDSGLEGAFTTADAFKEVGID
                     PVGVYENPVRDKAPLFIKNVNGIKVAILSYAYGFNGLESNLTEKEIANHLSNLDEKRMK
                     VEIERAEKEADVTVIMPQMGVEYRLEPTDEQVKLYHKMIDWGADIIFGGHPHVVEPSEV
                     VKKDGQQKLIIYSMGNFISNQRIETMDGVDSAAWTERGVLMDVTLEKKNCQTTIKTAQA
                     HPTWVNRTPKGTISPEGYPLYTYQTYILEDFIKGGKYRNKLDEETKERIDTAYKEMNAH
                     VNLKWK"
     CDS             13830..14096
                     /locus_tag="ctg13_19"
                     /transl_table=11
                     /translation="MKAIITVVGKDKAGIVAGVATKIAELGLNIDDITQTILDEFFTMM
                     AVVSSEDKKDFTHLRAELEAFGESLNVKINIQSSAIFDAMHNL"
ORIGIN
        1 caaaaagctc tataatctct acagtagttt tacccactac agaaattata gagccttttt
       61 tgttgaaatt tataaagttc accccaaaat tcaccccatg ttcaccctat tattttttta
      121 agcttctata tgcaatatct ccagcagttt gatttactat atttttgtgt taacataggt
      181 ctttgtaatt tgtttatcac tatgagttaa tgcctcggaa ataatttcta ggggaacgcc
      241 agattttctt gcaagagtgg cacctgtgtg tcttaactta tgtggtgaag caggggatag
      301 ttctggatgc ctacgtctga cagaattcat tctatagttg aggtaatctg tatgaagtgg
      361 aaggttgata ttattggatc ggtcattata ggtaaacaca aactgctttt gagtctggtg
      421 taaaccaaat agttttaatt ccttattatg aaacggttta ctttacggag gagttggcgc
      481 atgactttgc ctcatgggtg tctggagatt ctatggagcc aaagtatcac aatggttcag
      541 ttgctctcat tcgtgaaaca ggttttgact atgatggtgc cgtatatgct gtggtatgta
      601 atagtcaaac atacattaag cgagtatatc ttgaagcaga gggtctacgt ctaaagtata
      661 aggatatctt tatttcttat gacgaggatc cacgagtagt gagaattatt attggaaatt
      721 ttatacctct caaataatac gtttttctag tcctgaattg tcaacttgtt tgcttttttg
      781 ataatgattc tagttttcaa aaatgtaatg acatctgtta aggatttctt atgaaatatc
      841 ttctgataac agagcttgtt tgatagtaca gacggatttt attttataat actccgaaac
      901 aaaaagaatg aattttctaa aaattattga caaataaatt tgcttttagt attataaaca
      961 caacttaaag aagaggcaga gttatcatgg aaaatactga attttcattg gaacttgatg
     1021 taactgaagt ttcaacagaa caaggttatg tttctggtgg tgtaacatct acaggttgtt
     1081 gtaaagatta gttttataat tgattgaata aggcaggtat acgaggtact tacctttttt
     1141 tacaagagaa ttatgtttaa gataaaagat aattacattt ataggtaatg cgttaatgat
     1201 tcaagactta tagaaaaact tagtgaaaat aatcttgaaa tattttttga taacaaagtt
     1261 tttaaagaaa tgttgctagt ggcgaaccct caatttttcc ataatttaac taaagaaaaa
     1321 atatataaaa attccacctt tagaaactat gtaaaaagat caattacaag agcaacgccg
     1381 tttggattgt ttagttcaat tggtgtagga actttttctg atatctcata tcatcaaaag
     1441 attggagaaa attatacgaa aaaaatctcg gttagtggag agtggctaag ttcgatttgt
     1501 atgatgttag aaaataaaga ttctgtctta ttacaactac atatatagtg gaaccaaaaa
     1561 gtacttgaat tatcagataa gtatcaatta agtaatgtca attactgggg aatctctgag
     1621 ataagtaagg atttatttat caagaaaact ggacttttag aattcataca aaaattaacg
     1681 tataaatcgg aagtcagtgt gttagaactg gtacttcaaa gtaaatctcc tgatttagag
     1741 aagcagaaaa ttttagatta tatacgtaat ttgattacta atgaattttt gtttacaaac
     1801 ttgcgaaaag ttgcaataag ccataaagat ttagatgatt taaccaacat tttaaaggat
     1861 attaataacc aaagaaaatt aaccgaggat ttattacaaa taaaaaatag tattgagcag
     1921 tatgcaaaat tagagttggg agaaggcatt tctcaatata ctgaaatttg taaaaaaatg
     1981 tcgtatattt ttaatgataa aaaacagcat tacctgaagg tggatttagt aaattgttgt
     2041 gattcggtgc tgcccaaaaa tttaaaaaag aaaatggagg attttgttaa ttttatttca
     2101 aaaattaatc tggctaaagg ttatcgaaac agagaattag aatcatttac agaaaaattt
     2161 gttgaaaaat atggagaata cgtcgaagtt ccaattaaag aattattaga tggtaattta
     2221 ggactgggtt taccaaaaca aactttggga actcatgtaa agtcatcaag tagtgtagaa
     2281 gagcaaaatt ttttgtctta tctgagtaaa gaagtcttca aagctgttaa aaattgtaaa
     2341 aaagagatag atatatcaaa tataccttta ggattgttat acccaaattc ggatagattt
     2401 gttgcaaatc agttagagtt atattgtgaa attaagaatt ttgaatctca acctgttata
     2461 tcagttgtcc caaatacagg gagtgacatg atagggaagt ctattggaag gtttgcctcc
     2521 tattttccta attcttatat ctcgttagat tcacagttgg ataatgtaga attaatagaa
     2581 tttccaagag atagtaagaa tttaaatgtt atgtcggcac agaatgctca ttctaaaaag
     2641 ttattattat cttatgatga caatgataac acatcgattg aattagattc tgtggtggtg
     2701 ggggttataa aaacagaata tcgatataaa ttatatttta gggatttacg aaccggctca
     2761 attgttaatt ttgtaacaac atcaatgcta aatcataaat caaatggagt atttagcgat
     2821 ttagcaagat ttttgctagc ggtttcttta gaatggcaag ataatccgtt ttcagtgttt
     2881 aggataattg aaaattttga ttatcttccc tatattccca aaattaaata tggaaatata
     2941 attttaagtg aagagaagtg ggttttgtca gatatagata aaaatgattt atcttctatt
     3001 aaacagtgga aaaaagattt tgatgtacct agactactgt attttcataa agctgatgag
     3061 cgtctattgg tcgatttaga gaatgattta gatacacagt ggcttttaaa acaaaatgtg
     3121 gataaactgt attttacacg ttttgaaaaa tatgatggta aaaattgtga gtttatcttt
     3181 ggatttgaaa attatcaaag tagtataaat cattattcta tgcaggaaaa atctgttaga
     3241 agattgacaa ataactttta taagaaccat gttaaaacat tttcgagtga ttggatctat
     3301 tttagattat atggaattaa ttcatcaatt ctacttgaac taagagagcg gcttcttttg
     3361 tttacagacg agctattggt tgaaaagcta attagtgatt ttcattttgt aaattatagc
     3421 gataaggata atggatcgct tcgattacga tttaaaataa ataacgatga taattttgaa
     3481 gatttaagat ttcgaattgc acattggata gacttcctac tagaaagtgg tttttgtaat
     3541 gatgttagtt ttaatttata tgagagggaa attgagagat atggtggaga taactttata
     3601 acagtttgtg agaggatgtt ttctattgac agttttctta ccctaaagtt attttcgaag
     3661 aaattattaa atgataaaga tttattttct gttttgcatt cgacattttt atatattcga
     3721 ttattaggga tcccattaaa gcgattactt gagttgctga aggggaattt gactcaaaat
     3781 agatatcgta aaagttttaa aaagttattc ccaaataaca caatagtagt aaaggaattc
     3841 aaagaatatt ttgattacaa aaatcagttt gaaattttta atgaagtatt tagagagttc
     3901 ccgcctattg atggatattt tgaaggtaaa aatgatatag tctatagttt acttcatatg
     3961 catatgaata gagtaggcat gtttccatat agagaaaagg aatatcttta ttttatcatg
     4021 tatattgcag agccgttgaa taattataag gaatttactt aaaaagtatg aagaaattat
     4081 ctgtaaagta gataaactcg tgttggatag tgatattatt gacagattgc agagagcata
     4141 ttatacagaa aatagaagtt acttatcaga atatccaagt ataattatat atttatccta
     4201 taggttgata aattgtgata ataaggagta ttctaagctt ctctataata gagtaaatta
     4261 ttatctacaa gaattgctaa agtctattaa attgaatagc actaataata tttcactttg
     4321 ctatggattt acgggctatg tatatgcctt ggaattttta tctaaaaatt gtaaaggata
     4381 tgataaatta ctagatacac ttgagacaat tttattagct ttaacaaaag ataggctacg
     4441 tgaaataaaa agctctaata ttgttaaaga agaatacttt gatgtaattc aaggtgtctc
     4501 tagtgtagct agatatttgc ttagcaaaga ggaatcaact tctgaacaag agttattagt
     4561 aaaagaaata ttaaattact ttgcagacct aataattaac gagccaacta tttatgtgga
     4621 atatatgcca aatgaaaaat taaggaaaag atttcctagt ggctatatta atctaggtgt
     4681 agctcacggt atattgggac cactatacgt gttggcgtta ggatttgaaa aatttaatat
     4741 aacaaaacac ataccttcaa tagaaaaggg cttgagttac tatgagaacg ccttttttac
     4801 caatacaatt ggaaaaataa ttggttggaa tggtagagtc agtgattatg gggagaatga
     4861 ggaatttaga tttaatataa gttggtgcta tggcagtctt ggaatggcaa gagtactata
     4921 taatatagcg aaaatcattg atagtcagaa attacgagaa atggcgatgg atgtatttac
     4981 ttcatctatt gattacctta atagcagtga gattttaaat aatggaattt gtcatggacg
     5041 gtctggaata atgcttttgt tcaatttgat gtatttagat acaggaaaga cacaatttaa
     5101 agcaatttct gataatttat ttaaagaaat tataaatgat gcttctaatt ctgagtatat
     5161 atttgtggag cgtgacatat attttagagg cgtaaccttt gatgaagtta ttgattatat
     5221 tgactttgga ttgctaaatg gtgtttcagg gatagttata actctaatgg cacaaaggac
     5281 tggaaatgcc tacccattgg atagaatgct gtttatgcag tgaagttttt aagttaaagg
     5341 agaagtatga gaaaaatctt aaaaaacaaa ctatatctaa aagttctggt ttcggatttg
     5401 atatcaaatt ttggagatac attatacttt atagctctca tgacctatgt tacggagatt
     5461 aaggatagta atttagctat ttcaatcgtc aatatatcgg aaactctacc tattttattt
     5521 acaatatttt ttggtatcat tgcagataaa acgcttaata aagtgaaaat gattattaaa
     5581 acgttatggc tacgggtact gctatattta ttggttgctg tggctatgaa ttttaaacct
     5641 tctattatga tagtcataat tgctagtctc gttaatcttg ttgcagatac attgggacaa
     5701 tttgaaaatg gtctttttta tccaatttct aatcgaatag tgaaaaagtc agatagagaa
     5761 gaaactatgg cgtttaggca aactgttgtt tctgtgatga atattataaa tcaatcattg
     5821 ggtgcgtttt taattacttt ttttagtttt tctcacttag catttataaa tgctctaact
     5881 tttgctatta gtctgttaat tatgttagca atcaaaaatc aaattaatag ctattatgac
     5941 gagacgatct cgacaagtaa gatatcacaa tttgacttta aagcttcatt ttctgagatt
     6001 acttcaaatt taaagctctc gattaaccat ctatttagta tcggcaacat gaaggaagct
     6061 ttacttgtta taccaattct taatgggagt ttggcaattc tcacgccatt agttgttgtt
     6121 gatctttcta aagattctaa tttgacaatt attaattcag cgattacgat ctcgctttta
     6181 ggaattagca ctgtttcagg aggaatactt gggggcactt taattctaat tagtaaaaaa
     6241 tttaaaagcc tttccatagg cactttgcta aaaatgaatt taacgactgt tttactatca
     6301 ttcgttgctt tttacttcca aaatatttat ttaattatat tatcatcatt tctttcgagt
     6361 gtattagtta gtgcattaaa tcctaaaatg gggactatca tatttaataa tattgatgag
     6421 acgaagttgg ctacaatatt tggaggaatg gtgacatatt tccaaatagg ggatattgtg
     6481 tcaaggttat tgttttctac cttagtgatt tacttaccgt atggttatat cgcattaata
     6541 tatatagcag ttgtttttgt ggcaatttta tatacattaa aaagttcaaa tcacatagaa
     6601 agggaatttt aaattagtta aatgattata gttttccaaa ttttctacta ttgaaaacct
     6661 attttcaaga ttgagtacta aagttcgaga ttttgttcgt actcagctta gagaatttca
     6721 atatttggat gatgggcaat ttaaaacatt accagagtat ccagaatttg cttggtttga
     6781 agggatgtaa atgcggtaac tcatagaaat tgctccattt ttggcgatta tatccgaatt
     6841 atgatgtttg atgatcgatt agaaattcat agtccaggta agcttcctaa tatcgtaacg
     6901 gttgaaaata ttaagcacga acgtttttct cgtaatcctc gtattgctag aactttaaca
     6961 gaatttggat gggtacgaga aatgaatgag ggagtgaagc gaatctattc tgagatggaa
     7021 tcttatttct tgcatgaacc taaatacaca gagccaggaa ataaagttgt tttaactctt
     7081 gaaaataata ttttgagccg acatttgaga gttaatgata agatgatgaa aaaatatgac
     7141 gaattcaatg atttaaatga cgatgagaaa gcaattttac atatcatgta taataccgga
     7201 gagaaaatga ctactgcttt ggccgctaga ataacaaata ggggtagaaa ttttgcaagt
     7261 aaattattaa agagtcttgt aaataaagag atcctggaat ggcatggcac aagtaagcaa
     7321 gatagaaatc agtactatac tttggcagaa tagcggatct atttataact ggagtgcaga
     7381 agagtgcagt agttcggagt aaaacgcagt aagtgaattt cccctgtttt cctcaaaaaa
     7441 tctcaaactt tttgaaattc tggacaaaag aaaaggccta gttgcctgta gtttctacct
     7501 attaagttat attgaaattc attggtttaa aaccagatct taagaaagct cgtaaagctt
     7561 cacaattctc aaaacgttaa tcaatacgat tatatcaatg tttcaagaca ttcaagagtt
     7621 atctcttggg tgtctttttt tattcaaaat tcgatagttt ccaccaaagt ttccaccaat
     7681 tttccaccat tattttttca agctacgaaa tgcaatatcg cctactgtcc gattaactat
     7741 atcttttgta tttacataag tctttgtaat ttgcttatca ctatgagtta gagcttctga
     7801 aatagcttca agagaataac ctgcttgttt ggcaagagta acacctgcat gtcttagttt
     7861 gtgtggtgat gctggtgcaa gttctggatg tctccgtctg actgacttca ttctataatt
     7921 tagataatcc acgtgaagag gtaaattaat gttgtttgaa cgatcattat aggtgaatac
     7981 aaactgcttt tgagtttgac gcaatccaaa taattttaac tcctcttgtt gtcttgcttt
     8041 ccaattagct aatagctcaa ttaattcaat aggtgtttta aaaagggtct tcttacgacc
     8101 tttggtgggt tttatatttc cgaaacgatc taaagcttgt tctatcagtg tttctccagt
     8161 agagaaattg atgtgtttcc attgaagagc ataactttct gattttctat cggataaaaa
     8221 gaatgtcgta taaaagagag tgtagtcttt taaatcaata agtcctttct ctaagtctat
     8281 gtcaaaagct tgtaatcata atttcagctc ttctttatcg agagataaat cttcctctcg
     8341 tttgctttct ttaaggagaa tctttttatt agctttaatt ctagtaattg ttttgcggag
     8401 tttatttgat ggaatatatt ctagttcctc agcccaatcg aaaacagaat taacatagct
     8461 cctaattact ttgaaattag catagctatt tgctttggga gtaagtaatg aaagaataag
     8521 ttgtttatta ttatttgggt attcgataga atatttaccc agaatgggta aaatgtgtag
     8581 cctgaatata ttttctgttt ggaaaactgt tgcttttgtg ggtggtttta ttgttgttgt
     8641 ggtttgacct gctttgtatg gttcgagcca aatatcttca taaaattttt tgaatatgat
     8701 ttctccttta ttttttatgt ttatatggct ttttccagac ttagcatttt taatgtcgat
     8761 agaaagtttt aattctactt ctttggcttc tcgtctggtt ttatattttc tttcaaaaag
     8821 tttacctaaa cccaattttg cttgaacatc ttctggaatg taaagtcgta attgatatgt
     8881 tccatttttt gttttcttaa tagacatatt tacctcctta tgcgctgatt tctaatcttg
     8941 tcatccattg attgatactt ttcttgttga aacgaataga ttttccgatt cggatatagg
     9001 gtaatcccat tgcaatccca atatcaagtg tattattaga gatacctagg tagttgtaag
     9061 tctgtttttt gtttagaaaa gtgctgtcag ccccaatatc ctctttaaaa tgatgaattt
     9121 cattctttat tagtgttgca atcatttgct gaatttcttg agtttgttct tctggcaatt
     9181 gtactagcat atattattct cctcttaaaa ataaaaaaga agagtaaaat actctcctgc
     9241 tgttaaaaag attaattctt cttatttatt attttgttga aaaaaactag caaagcgacc
     9301 ccgaccactg tcaattgttt gcccttatta cgacatgcat cacaaattgg tattgtttta
     9361 ggtgatgaga ttgttttttt acaagtttta cacttcttcg tttttagtgt catttttttc
     9421 tccgtttcga tttttgctgt ttcggtattg cttaagttaa cgttactatc ttggtggaat
     9481 tcaattaatt tagtattaat attaataaat aagtccctat tgttttttga gtagctgtaa
     9541 tgattatgaa ttaattctaa caaacttact tttgggatac tattattctt tatccatttt
     9601 aattctttta cataaagaag tttttttgct agttctttca aataatttgt tttgtatgga
     9661 atattttgtt tagaaactaa ttccatcgaa ccttgaaaag atagtagccg atcatgggct
     9721 atcccctcat tatttagtgt taaatcgata taaatttgca taccaacaat tttagtcata
     9781 atttctatgt cttgaagtaa aaaatcagca tgtgtttgta aagaggcttg acggtatgtt
     9841 ggttggctga ttttcttaat aatttcatct ctatttgaaa ttatatcaga tttaatagca
     9901 cttactgatt cttcaaataa tgtatttgca tcctttagtg acttaacttt ttctctgaaa
     9961 tctttgctat tgttggcttc tataactttt gtacgagctg aataaaatgg agctagtata
    10021 ctattatttc tttcccatct aatctgataa tcttgatttt ctttgatatc taacagtaag
    10081 ttatagattt gtttaagttg agcttgagcg attagatcac taggaacttg attttcgttg
    10141 ttattagtca ttttccttaa tgtcaaatct tcaacacgat tcttctgatc ggttgtgtct
    10201 acaattacag ccctaagatt tccttctact tttctagatt ccccaatttt ataagcgccc
    10261 tcttgaagtt tcgctttggt gtcaggagat agactgtcaa agtcaacctc atatagagta
    10321 gcattattga aatctagtat tttagtgtta ggattaagat attggtttga aaagttgaat
    10381 ggaggggttc ctttagtatc aaataagttt aagatatcaa atgggaaact ttctttaatc
    10441 atgttgggga gagcttgttc aaaaggacta cttatttcaa agatatctgt tgttttgata
    10501 tctgtctcat ttttaaataa atcaaaagat tgtaagtttt tttgattgat tcttcttttt
    10561 gcttttctga tttagcaact tcgttcatta gatcacctag tcatttttgt attaattata
    10621 acatttagta ttgattttaa acgtatctaa attaataata ctaaaaatta atattattaa
    10681 aaccatcatc agtgtccaat gacataagta atttgttttg ctgtttctgc atcaaaagtg
    10741 cggtagctaa cgactcctag tcctttgata tttgattcag agatgaggat ggagccatct
    10801 gatttgactt gttccacaaa ggcgatgtgg ccataagttg gatctgctcc agcttgccct
    10861 gggctaaaag atagagcgga gtgttcggtt ggggtatgag ttgtctgata ccctggggca
    10921 ttcatccatt ggccaccatt tcccatatac tttccgaagc taacaccgac ttcttttcct
    10981 cggttataga caaaccaggt acattgtccc caaggataag acagtcctgt gtggcttgag
    11041 gtattgattt ctttggtgag gctatagcct tgtgggacat cccctgttgt gacaccgcct
    11101 ccgtctctgg tttttccttt cgtctgttca ggggcttttg gtgtacctcc atgctcatcg
    11161 atataggtat cgagtttttg catggtttca gcacgccctt tcctagagcc agaggtatcg
    11221 gtgaagtaga cgccaccatc tgttgacgtg ttgagagaac cactcgcaaa tttttgcgct
    11281 ttgtcatctt ggacttttaa ggtttcattt ttattgccaa tgatggtctg ctttgtgagt
    11341 ccaacaacgg ctacttcatc gttaaaatta ttggcatttt ctggattaga gtcaaatgcg
    11401 gttctgttgc aaagttttaa ataaagaata aaatccctta cggtatctat gatttaagct
    11461 gggattccca ataatacctt gatttcagta cagaccgaaa acccgaagag agtgccttct
    11521 tttcgagttt tcttatataa tcctcggatg gcttccatgc ctttaatcgt ggtagaggca
    11581 gtgcgtaaac ttcgatagaa tttattgtgt ctctttactg gacgatggtc ttgttcaatc
    11641 aaattattca ggtatttaat ggtacaatgt tctgtccctt gataaaagcc ccgtattctc
    11701 ttagtttctt aaaggcactt gtaatagagg gggctttatc tgtgactaca accttcggtt
    11761 catcaaactg cttaactaac cgctcaagaa aagcataggc tgtttgtgtg tcccgttttt
    11821 tacgtaacca aatatccaag gttaaaccat ctgcatcgat ggctcgatac aaataatgcc
    11881 attttccttt aattttgatg tatatttcat ccattttcca tgaataaaag gattttttat
    11941 ttttcttttt ccaaatttga tagagtagtt tgccatattc ttgcacccaa tgataaatcg
    12001 tcgtatgaga aacgttaatg ccacgatcat ataagatttc ttgaacttca cgatagctaa
    12061 ggttataacg aagataatag cccacggtta caataatcac atcctgctga aattgctttc
    12121 ctttaaaatg atttatcgtc attcctcctg ctatcttttt ctattattct acctgatttg
    12181 atagtagatt taaaactttg caacagaacc gatgtaaccg tttattaatc ttttttatca
    12241 tctatggata acattttttt gttacactag gagtatgaaa aaggagatat gatgaaacag
    12301 agccaagcta aaaagcatga caatacgatg actaataaga ttttgatgag gttgattgct
    12361 cttgtcttag gtttgctttt tcttgaaatt ttgattattc atagtaaaaa tgagcagcaa
    12421 aagagtgttt caaatcaagt acagacagca cgtatcatgg ctaatgggga cttgctttat
    12481 catgacggtc tctatatgag tgccttgcag gcagatggca gttatgattt tactgaaaat
    12541 tttacatatg tgaagccatg gttaaagcag gctgatttgg tcttgggtga ttttgaggga
    12601 actatcaatc ctgattatcc tttgtcaggc taccctctgt ttaatgctcc tcaatcagtg
    12661 acggcagcta ttagtgatgc cggctatgat gttatggatt tggcccataa tcatattttg
    12721 gactctggtt tagagggagc ttttacaaca gccgatgcat ttaaagaggt gggcattgac
    12781 cctgttggtg tttatgaaaa tcctgtgcgt gataaggcgc ctctgtttat caagaatgtt
    12841 aatggcatca aggtggcaat actttcttat gcctatggtt tcaatggctt ggagtcaaat
    12901 ctgaccgaaa aagagattgc gaatcatttg tcgaatcttg atgaaaaacg gatgaaagta
    12961 gagattgagc gtgctgaaaa agaggctgac gttacggtta ttatgccaca gatgggcgtg
    13021 gaatatcgtt tggaaccgac agatgaacag gtaaagcttt accataagat gattgattgg
    13081 ggtgctgata ttatctttgg gggccaccct catgtggttg agccgtctga agtggttaaa
    13141 aaggatggac agcaaaaact cattatttac tcaatgggga atttcatctc taaccagcgc
    13201 atagagacta tggatggtgt ggatagtgca gcatggacag agaggggcgt cttaatggat
    13261 gtcactcttg agaaaaagaa ttgtcaaacc acgattaaga cagctcaagc gcatccaacc
    13321 tgggttaacc gcacacccaa gggaacaatt tcgccagagg gatatccttt atatacttat
    13381 caaacctata ttttagagga tttcattaaa ggtggaaaat acagaaataa actagatgaa
    13441 gaaactaaag agcgtataga tactgcctat aaagaaatga atgctcatgt taatctaaaa
    13501 tggaaataaa gctaagatat cgctaaaatt tggcgatatt tttctttatc gacaagttac
    13561 caacagactt atccacaggt gtggataagt ctgttctcag tgttaaacct tgatttttca
    13621 aggttttatt agaattgtat tgttttactt gttaacaagt ttatccacaa gttgttgaat
    13681 tgatagagac tgaattttat aaacgatact ggttaaatgt tgtagaaaca ttcgtttttt
    13741 tcaataaaaa aggtgtaatt tctataaaaa atagcgtttt taatcaaaat atgctaaaat
    13801 tatataaaat aaaatgatgg aggcttctca tgaaagcgat tattacagtt gtaggtaagg
    13861 ataaagcggg tattgttgca ggtgttgcga ctaagatcgc agaacttggt ttgaatattg
    13921 atgatatcac tcaaacaatc cttgatgaat tctttaccat gatggcggtt gtatcatcgg
    13981 aagataagaa agattttaca cacctacgtg ctgaattaga agcttttggt gaatcattaa
    14041 acgtcaaaat caatatccaa agctcagcga tttttgatgc tatgcacaac ttataagata
    14101 ggggtagttg aaaatggata ttaaacaggt tacagaaacc attgctatga ttgaggagca
    14161 gaactttgat gttcgtacta tcaccatggg aatttcactt ctagactgta tcgattcaga
    14221 tattgataag gcagcagaaa aggtatacaa caagattgtt tctaaggcta agaacttggt
    14281 agctgttggt gacgaaattg cggctgaact tggtattcca attgttaata aacgtgtttc
    14341 tgttactccg atttcaatta tcggtgcggc gacagatgcg acagattatg taccgtttgc
    14401 tagggcacta gaccgtgcag ctaaggaaat tggcattaac tttattggtg gtttctctgc
    14461 attagttcaa aagggctacc aaaaaggtga tgagattctt attgattcta tcccacgtgc
    14521 gcttgctgag actgattttg tctgctcatc tgttaatatt ggttcaacaa aaactggtat
    14581 taacatgaca gcggtacgtg atatgggacg tatcattaaa gaggcttctg aggcagatcc
    14641 aatgggtcca ggtaaattgg ttgtctttgc taatgcggtt gaagataatc catttatggc
    14701 aggtgccttc cacggtgttg gtgaggctga cgttgtaatc aatgttgggg tttcaggtcc
    14761 tggtgttgtg caacgtgctg ttgagaaggt ttcaggtgaa agttttgatg ttttagctga
    14821 aacagttaag aaaactgcct ttaaaatcac acgtgtaggg cagttggttg gtcaaatggc
    14881 tagcgaacgt ctaggtgtcg agtttggtat tgtagacttg tctcttgcac caactccagc
    14941 agtaggtgat tcggtagctc gtgtacttga agccatgggg cttgaagttg ttggtacgca
    15001 tggtactact gcggctctag ctcttcttaa tgaccaagtt aaaaaaggtg gtatcatggc
    15061 atgtaaccag gtcggtggtt tgtcaggtgc ctttatccca gtttctgaag atgaaggaat
    15121 gattgcagca gttcaatctg ggcatatcaa ccttgaaaaa ttggaagcca tgacggctat
    15181 ctgttctgtt ggtctagaca tgattgccat tcctgctgat acgccagata caacaattgc
    15241 ggccatgatt gccgatgaag cggctattgg tgtcattaat cagaaaacaa cagctgttcg
    15301 tattattcct tatggtaagg aag
//
