LOCUS       c00017_JAIQWL0..       15267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIQWL010000025.1 Streptococcus thermophilus strain CF10_14
            NODE_25_length_24808_cov_29.863128, whole genome shotgun sequence.
ACCESSION   JAIQWL010000025
VERSION     JAIQWL010000025
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:17:05
            Original ID  :: JAIQWL010000025.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 9541
            Orig. end    :: 24808
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15267
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[19541:23595]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14054
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..15267
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15267
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     CDS             complement(1229..1495)
                     /locus_tag="ctg17_13"
                     /transl_table=11
                     /translation="MKAIITVVGKDKAGIVAGVATKIAELGLNIDDITQTILDEFFTMM
                     AVVSSEDKKDFTHLRAELEAFGESLNVKINIQSSAIFDAMHNL"
     CDS             complement(1816..3033)
                     /locus_tag="ctg17_14"
                     /transl_table=11
                     /translation="MKQSQAKKHDNTMTNKILMRLIALVLGLLFLEILIIHSKNEQQKS
                     VSNQVQTARIMANGDLLYHDGLYMSALQADGSYDFTENFTYVKPWLKQADLVLGDFEGT
                     INPDYPLSGYPLFNAPQSVTAAISDAGYDVMDLAHNHILDSGLEGAFTTADAFKEVGID
                     PVGVYENPVRDKAPLFIKNVNGIKVAILSYAYGFNGLESNLTEKEIANHLSNLDEKRMK
                     VEIERAEKEADVTVIMPQMGVEYRLEPTDEQVKLYHKMIDWGADIIFGGHPHVVEPSEV
                     VKKDGQQKLIIYSMGNFISNQRIETMDGVDSAAWTERGVLMDVTLEKKNCQTTIKTAQA
                     HPTWVNRTPKGTISPEGYPLYTYQTYILEDFIKGGKYRNKLDEETKERIDTAYKEMNAH
                     VNLKWK"
     CDS             3183..3677
                     /locus_tag="ctg17_15"
                     /transl_table=11
                     /translation="MTINHFKGKQFQQDVIIVTVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDEIYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQTAYAFLERLVKQFDEPKVVVTDKAPSITSAFKKLREYGAFIKGQNIVPLN
                     T"
     CDS             3683..3871
                     /locus_tag="ctg17_16"
                     /transl_table=11
                     /translation="LIEQDHRPVKRHNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTL
                     FGFSVCTEIKVLLGIPA"
     CDS             4062..4403
                     /locus_tag="ctg17_17"
                     /transl_table=11
                     /translation="VVLSTRQQMVASTSPIPLALGKGVLKPCKNSIPISMSMEVHQKPL
                     NRRKEKPETEAVSQQGMSHKAIASPKKSIPQATQDCLILGDNVPGLSITEEKKSVLASE
                     SIWEMVANG"
     CDS             4379..4636
                     /locus_tag="ctg17_18"
                     /transl_table=11
                     /translation="MGNGGQWMNAPGYQTTHTPTEHSALSFSPGQAGADPTYGHIAFVE
                     QVKSDGSILISESNIKGLGVVSYRTFDAETAKQITYVIGH"
     CDS             4883..6073
                     /locus_tag="ctg17_19"
                     /transl_table=11
                     /translation="MIKESFPFDILNLFDTKGTPPFNFSNQYLNPNTKILDFNNATLYE
                     VDFDSLSPDTKAKLQEGAYKIGESRKVEGNLRAVIVDTTDQKNRVEDLTLRKMTNNNEN
                     QVPSDLIAQAQLKQIYNLLLDIKESQDYQIRWERNNSILAPFYSARTKVIEANNSKDFR
                     EKVKSLKDANTLFEESVSAIKSDIISNRDEIIKKISQPTYRQASLQTHADFLLQDIEIM
                     TKIVGMQIYIDLTLNNEGIAHDRLLSFQGSMELVSKQNIPYKTNYLKELAKKLLYVKEL
                     KWIKNNSIPKVSLLELIHNHYSYSKNNRDLFININTKLIEFHQDSNVNLSNTETAKIET
                     EKKMTLKTKKCKTCKKTISSPKTIPICDACRNKGKQLTVVGVALLVFFNKIINKKN"
     CDS             6135..6407
                     /locus_tag="ctg17_20"
                     /transl_table=11
                     /translation="MLVQLPEEQTQEIQQMIATLIKNEIHHFKEDIGADSTFLNKKQTY
                     NYLGISNNTLDIGIAMGLPYIRIGKSISFNKKSINQWMTRLEISA"
     CDS             6418..7635
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 110.6; E-value: 2.2e-33)"
                     /gene_kind="other"
                     /locus_tag="ctg17_21"
                     /transl_table=11
                     /translation="MSIKKTKNGTYQLRLYIPEDVQAKLGLGKLFERKYKTRREAKEVE
                     LKLSIDIKNAKSGKSHINIKNKGEIIFKKFYEDIWLEPYKAGQTTTTIKPPTKATVFQT
                     ENIFRLHILPILGKYSIEYPNNNKQLILSLLTPKANSYANFKVIRSYVNSVFDWAEELE
                     YIPSNKLRKTITRIKANKKILLKESKREEDLSLDKEELKLWLQAFDIDLEKGLIDLKDY
                     TLFYTTFFLSDRKSESYALQWKHINFSTGETLIEQALDRFGNIKPTKGRKKTLFKTPIE
                     LIELLANWKARQQEELKLFGLRQTQKQFVFTYNDRSNNINLPLHVDYLNYRMKSVRRRH
                     PELAPASPHKLRHAGVTLAKQAGYSLEAISEALTHSDKQITKTYVNTKDIVNRTVGDIA
                     FRSLKK"
     CDS             complement(7923..8021)
                     /locus_tag="ctg17_22"
                     /transl_table=11
                     /translation="MAQVSKIEISTILWQNSGSIYNWSAEECSSSE"
     CDS             complement(7972..8484)
                     /locus_tag="ctg17_23"
                     /transl_table=11
                     /translation="MMFDDRLEIYSPGKLPNIVTVENIKHERFSRNPRIARTLTEFGWV
                     REMNEGVKRIYSEMESYFLHEPKYTEPGNKVVLTLENNILSRHLRVNDKMMKKYDEFND
                     LNDDEKAILHIMYNTGEKMTTALAARITNRGRNFASKLLKSLVNKEILEWHGTSKQDRN
                     QYYTLAE"
     CDS             complement(8712..9977)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 93.6; E-value: 2e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg17_24"
                     /transl_table=11
                     /translation="MRKILKNKLYLKVLVSDLISNFGDTLYFIALMTYVTEIKESNLAI
                     SIVNISETLPILFTIFFGIIADKTLNKVKMIIKTLWLRVILYLLVAVAMNFKPSIIVVI
                     IASLVNLVADTLGQFENGLFYPISNRIVKKSDREETMAFRQTVVSTMNIVNQSLGAFLI
                     TFFSFSHLAFINSLTFAISLLIMLAIRNQINSYYDETISTSKISQFDFKASFSEIISNL
                     KLSINHLFSIGNMKEALLVIPILNGSLAILIPLVVVNLSKDSNLTIVNSAITISLLGIS
                     TVSGGILGGTLILISKKFKSLSIGTLLKMNLTIVLLSFVAFYFQNIYLIILSSFLSSVL
                     VSALNPKMGTIIFNNIDETKLATIFGGMVTYFQIGDIVSRLLFSTLVIYLPYGYIALIY
                     IAVVFVAILYTLKSSNHIEREF"
     CDS             complement(10001..11224)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     308.8; E-value: 9.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_25"
                     /sec_met_domain="LANC_like (E-value: 3.1e-52, bitscore:
                     168.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLDSDIIDRLQRAYYTENRSYLSEYPSIIIYLSYRLINCDNKEYS
                     KLLYNRVNYYLQELLKSIKLNSTNNISLCYGFTGYVYALEFLSKNCKGYDKLLDTLETI
                     LLALTKDRLREIKSSNIVKEEYFDVIQGVSSVARYLLSKEESTSEQELLVKEILNYFAD
                     LIINEPTIYVEYMPNEKLRKRFPSGYINLGVAHGILGPLYVLALGFEKFNITKHIPSIE
                     KGLSYYENAFFTNTIGKIIGWNGRVSDYEENEEFRFNISWCYGSLGMARVLYNIAKIID
                     SQKLREMAMDVFTSSIDYLNSSEILNNGICHGRSGIMLLFNLMYLDTGKTQFKAISDNL
                     FKEIINDASNSEYIFVERDIYFRGVTFDEVIDYIDFGLLNGVSGIVITLMAQRTGNAYP
                     LDRMLFMQ"
     CDS             complement(11262..13625)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     577; E-value: 1.1e-174)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_26"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.7e-65, bitscore:
                     210.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.9e-19, bitscore:
                     59.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLELVLQSKSPDLEKQKILDYIRNLITNEFLFTNLRKVAISHKDL
                     DDLTNILKDINNQRKLTEDLLQIKNSIEQYAKLELGEGISQYTEICKKMSYIFNDKKQH
                     YLKVDLVNCCDSVLPKNLKKKMEDFVNFISKINLAKGYRNRELESFTEKFVEKYGEYVE
                     VPIKELLDGNLGLGLPKQTLGTHVKSSSSVEEQNFLSYLSKEVFKAVKNCKKEIDISNI
                     PLGLLYPNSDRFVANQLELYCEIKNFESQPVISVVPNTGSDMIGKSIGRFASYFPNSYI
                     SLDSQLDNVELIEFPRDSKNLNVMSAQNAHSKKLLLSYDDNDNTSIELDSVVVGVIKTE
                     YRYKLYFRDLRTGSIVNFVTTSMLNHKSNGVFSDLARFLLAVSLEWQDNPFSVFRIIEN
                     FDYLPYIPKIKYGNIILSEEKWVLSDIDKNDLSSIKQWKKDFDVPRLLYFHKADERLLV
                     DLENDLDTQWLLKQNVDKLYFTRFEKYDGKNCEFIFGFENYQSSINHYSMQEKSVRRLT
                     NNFYKNYVKTFSSDWIYFRLYGINSSILLELRERLLLFTDELLVEKLISDFHFVNYSDK
                     DNGSLRLRFKINNDDNFEDLRFRIAHWIDFLLESGFCNDVSFNLYEREIERYGGDNFIT
                     VCERMFSIDSFLTLKLFSKKLLNDKDLFSVLHSTFLYIRLLGIPLKRLLELLKGNLTQN
                     RYRKSFKKLFPNNTIVVKEFKEYFDYKNQFEIFNEVFREFPPIDGYFEGKNDIVYSLLH
                     MHMNRVGMFPYREKEYLYFIMYIAEPLNNYKEFT"
     CDS             complement(13776..14054)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_27"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.2e-15, bitscore:
                     45.2, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVANPQFFHNLTKEKIYKNSTFRNYVKRSITRATPFGLFSSIG
                     VGTFSDISYHQKIGENYTKKISVSGEWLSSICMMLENKDSVLLQLHI"
     CDS             complement(14233..14337)
                     /locus_tag="ctg17_28"
                     /transl_table=11
                     /translation="MENTEFSLELDVTEVSTEQGYVSGGVTSTGCCKD"
     CDS             complement(14587..14850)
                     /locus_tag="ctg17_29"
                     /transl_table=11
                     /translation="LAHDFASWVSGDSMEPKYHNGSVALIRETGFDYDGAVYAVVCNSQ
                     TYIKRVYLEAEGLRLKYKDIFISYDEDPRVVRIIIGNFIPLK"
     CDS             14925..15167
                     /locus_tag="ctg17_30"
                     /transl_table=11
                     /translation="VFTYNDRSNNINLPLHTDYLNYRMNSVRRRHPELSPASPHKLRHT
                     GATLARKSGVPLEIISEALTHSDKQITKTYVNTKI"
ORIGIN
        1 ccttccttac cataaggaat aatacgaaca gctgttgttt tctgattaat gacaccaata
       61 gccgcttcat cggcaatcat ggccgcaatt gttgtatctg gcgtatcagc aggaatggca
      121 atcatgtcta gaccaacaga acagatagcc gtcatggctt ccaatttttc aaggttgata
      181 tgcccagatt gaactgctgc aatcattcct tcatcttcag aaactgggat aaaggcacct
      241 gacaaaccac cgacctggtt acatgccatg ataccacctt ttttaacttg gtcattaaga
      301 agagctagag ccgcagtagt accatgcgta ccaacaactt caagccccat ggcttcaagt
      361 acacgagcta ccgaatcacc tactgctgga gttggtgcaa gagacaagtc tacaatacca
      421 aactcgacac ctagacgttc gctagccatt tgaccaacca actgccctac acgtgtgatt
      481 ttaaaggcag ttttcttaac tgtttcagct aaaacatcaa aactttcacc tgaaaccttc
      541 tcaacagcac gttgcacaac accaggacct gaaaccccaa cattgattac aacgtcagcc
      601 tcaccaacac cgtggaaggc acctgccata aatggattat cttcaaccgc attagcaaag
      661 acaaccaatt tacctggacc cattggatct gcctcagaag cctctttaat gatacgtccc
      721 atatcacgta ccgctgtcat gttaatacca gtttttgttg aaccaatatt aacagatgag
      781 cagacaaaat cagtctcagc aagcgcacgt gggatagaat caataagaat ctcatcacct
      841 ttttggtagc ccttttgaac taatgcagag aaaccaccaa taaagttaat gccaatttcc
      901 ttagctgcac ggtctagtgc cctagcaaac ggtacataat ctgtcgcatc tgtcgccgca
      961 ccgataattg aaatcggagt aacagaaaca cgtttattaa caatcggaat accaagttca
     1021 gccgcaattt cgtcaccaac agctaccaag ttcttagcct tagaaacaat cttgttgtat
     1081 accttttctg ctgccttatc aatatctgaa tcgatacagt ctagaagtga aattcccatg
     1141 gtgatagtac gaacatcaaa gttctgctcc tcaatcatag caatggtttc tgtaacctgt
     1201 ttaatatcca ttttcaacta cccctatctt ataagttgtg catagcatca aaaatcgctg
     1261 agctttggat attgattttg acgtttaatg attcaccaaa agcttctaat tcagcacgta
     1321 ggtgtgtaaa atctttctta tcttccgatg atacaaccgc catcatggta aagaattcat
     1381 caaggattgt ttgagtgata tcatcaatat tcaaaccaag ttctgcgatc ttagtcgcaa
     1441 cacctgcaac aatacccgct ttatccttac ctacaactgt aataatcgct ttcatgagaa
     1501 gcctccatca ttttatttta tataatttta gcatattttg attaaaaacg ctatttttta
     1561 tagaaattac acctttttta ttgaaaaaaa cgaatgtttc tacaacattt aaccagtatc
     1621 gtttataaaa ttcagtctct atcaattcaa caacttgtgg ataaacttgt taacaagtaa
     1681 aacaatacaa ttctaataaa accttgaaaa atcaaggttt aacactgaga acagacttat
     1741 ccacacctgt ggataagtct gttggtaact tgtcgataaa gaaaaatatc gccaaatttt
     1801 agcgatatct tagctttatt tccattttag attaacatga gcattcattt ctttataggc
     1861 agtatctata cgctctttag tttcttcatc tagtttattt ctgtattttc cacctttaat
     1921 gaaatcctct aaaatatagg tttgataagt atataaagga tatccctctg gcgaaattgt
     1981 tcccttgggt gtgcggttaa cccaggttgg atgcgcttga gctgtcttaa tcgtggtttg
     2041 acaattcttt ttctcaagag tgacatccat taagacgccc ctctctgtcc atgctgcact
     2101 atccacacca tccatagtct ctatgcgctg gttagagatg aaattcccca ttgagtaaat
     2161 aatgagtttt tgctgtccat cctttttaac cacttcagac ggctcaacca catgagggtg
     2221 gcccccaaag ataatatcag caccccaatc aatcatctta tggtaaagct ttacctgttc
     2281 atctgtcggt tccaaacgat attccacgcc catctgtggc ataataaccg taacgtcagc
     2341 ctctttttca gcacgctcaa tctctacttt catccgtttt tcatcaagat tcgacaaatg
     2401 attcgcaatc tctttttcgg tcagatttga ctccaagcca ttgaaaccat aggcataaga
     2461 aagtattgcc accttgatgc cattaacatt cttgataaac agaggcgcct tatcacgcac
     2521 aggattttca taaacaccaa cagggtcaat gcccacctct ttaaatgcat cggctgttgt
     2581 aaaagctccc tctaaaccag agtccaaaat atgattatgg gccaaatcca taacatcata
     2641 gccggcatca ctaatagctg ccgtcactga ttgaggagca ttaaacagag ggtagcctga
     2701 caaaggataa tcaggattga tagttccctc aaaatcaccc aagaccaaat cagcctgctt
     2761 taaccatggc ttcacatatg taaaattttc agtaaaatca taactgccat ctgcctgcaa
     2821 ggcactcata tagagaccgt catgataaag caagtcccca ttagccatga tacgtgctgt
     2881 ctgtacttga tttgaaacac tcttttgctg ctcattttta ctatgaataa tcaaaatttc
     2941 aagaaaaagc aaacctaaga caagagcaat caacctcatc aaaatcttat tagtcatcgt
     3001 attgtcatgc tttttagctt ggctctgttt catcatatct cctttttcat actcctagtg
     3061 taacaaaaaa atgttatcca tagatgataa aaaagattaa taaacggtta catcggttct
     3121 gttgcaaagt tttaaatcta ctatcaaatc aggtagaata atagaaaaag atagcaggag
     3181 gaatgacgat aaatcatttt aaaggaaagc aatttcagca ggatgtgatt attgtaaccg
     3241 tgggctatta tcttcgttat aaccttagct atcgtgaagt tcaagaaatc ttatatgatc
     3301 gtggcattaa cgtttctcat acgacgattt atcgttgggt gcaagaatat ggcaaactac
     3361 tctatcaaat ttggaaaaag aaaaataaaa aatcctttta ttcatggaaa atggatgaaa
     3421 tatacatcaa aattaaagga aaatggcatt atttgtatcg agccatcgat gcagatggtt
     3481 taaccttgga tatttggtta cgtaaaaaac gggacacaca aacagcctat gcttttcttg
     3541 agcggttagt taagcagttt gatgaaccga aggttgtagt cacagataaa gccccctcta
     3601 ttacaagtgc ctttaagaaa ctaagagaat acggggcttt tatcaaggga cagaacattg
     3661 taccattaaa tacctgaata atttgattga acaagaccat cgtccagtaa agagacacaa
     3721 taaattctat cgaagtttac gcactgcctc taccacgatt aaaggcatgg aagccatccg
     3781 aggattatat aagaaaactc gaaaagaagg cactctcttc gggttttcgg tctgtactga
     3841 aatcaaggta ttattgggaa tcccagctta aatcatagat accgtaaggg attttattct
     3901 ttatttaaaa ctttgcaaca gaaccgcatt tgactctaat ccagaaaatg ccaataattt
     3961 taacgatgaa gtagccgttg ttggactcac aaagcagacc atcattggca ataaaaatga
     4021 aaccttaaaa gtccaagatg acaaagcgca aaaatttgcg agtggttctc tcaacacgtc
     4081 aacagatggt ggcgtctact tcaccgatac ctctggctct aggaaagggc gtgctgaaac
     4141 catgcaaaaa ctcgatacct atatcgatga gcatggaggt acaccaaaag cccctgaaca
     4201 gacgaaagga aaaaccagag acggaggcgg tgtcacaaca ggggatgtcc cacaaggcta
     4261 tagcctcacc aaagaaatca atacctcaag ccacacagga ctgtcttatc cttggggaca
     4321 atgtacctgg tttgtctata accgaggaaa agaagtcggt gttagcttcg gaaagtatat
     4381 gggaaatggt ggccaatgga tgaatgcccc agggtatcag acaactcata ccccaaccga
     4441 acactccgct ctatctttta gcccagggca agctggagca gatccaactt atggccacat
     4501 cgcctttgtg gaacaagtca aatcagatgg ctccatcctc atctctgaat caaatatcaa
     4561 aggactagga gtcgttagct accgcacttt tgatgcagaa acagcaaaac aaattactta
     4621 tgtcattgga cactgatgat ggttttaata atattaattt ttagtattat taatttagat
     4681 acgtttaaaa tcaatactaa atgttataat taatacaaaa atgactaggt gatctaatga
     4741 acgaagttgc taaatcagaa aagcaaaaag aagaatcaat caaaaaaact tacaatcttt
     4801 tgatttattt aaaaatgaga cagatatcaa aacaacagat atctttgaaa taagtagtcc
     4861 ttttgaacaa gctctcccca acatgattaa agaaagtttc ccatttgata tcttaaactt
     4921 atttgatact aaaggaaccc ctccattcaa cttttcaaac caatatctta atcctaacac
     4981 taaaatacta gatttcaata atgctactct atatgaggtt gactttgaca gtctatctcc
     5041 tgacaccaaa gcgaaacttc aagagggcgc ttataaaatt ggggaatcta gaaaagtaga
     5101 aggaaatctt agggctgtaa ttgtagacac aaccgatcag aagaatcgtg ttgaagattt
     5161 gacattaagg aaaatgacta ataacaacga aaatcaagtt cctagtgatc taatcgctca
     5221 agctcaactt aaacaaatct ataacttact gttagatatc aaagaaagtc aagattatca
     5281 gattagatgg gaaagaaata atagtatact agctccattt tattcagctc gtacaaaagt
     5341 tatagaagcc aacaatagca aagatttcag agaaaaagtt aagtcactaa aggatgcaaa
     5401 tacattattt gaagaatcag taagtgctat taaatctgat ataatttcaa atagagatga
     5461 aattattaag aaaatcagcc aaccaacata ccgtcaagcc tctttacaaa cacatgctga
     5521 ttttttactt caagacatag aaattatgac taaaattgtt ggtatgcaaa tttatatcga
     5581 tttaacacta aataatgagg ggatagccca tgatcggcta ctatcttttc aaggttcgat
     5641 ggaattagtt tctaaacaaa atattccata caaaacaaat tatttgaaag aactagcaaa
     5701 aaaacttctt tatgtaaaag aattaaaatg gataaagaat aatagtatcc caaaagtaag
     5761 tttgttagaa ttaattcata atcattacag ctactcaaaa aacaataggg acttatttat
     5821 taatattaat actaaattaa ttgaattcca ccaagatagt aacgttaact taagcaatac
     5881 cgaaacagca aaaatcgaaa cggagaaaaa aatgacacta aaaacgaaga agtgtaaaac
     5941 ttgtaaaaaa acaatctcat cacctaaaac aataccaatt tgtgatgcat gtcgtaataa
     6001 gggcaaacaa ttgacagtgg tcggggtcgc tttgctagtt tttttcaaca aaataataaa
     6061 taagaagaat taatcttttt aacagcagga gagtatttta ctcttctttt ttatttttaa
     6121 gaggagaata atatatgcta gtacaattgc cagaagaaca aactcaagaa attcagcaaa
     6181 tgattgcaac actaataaag aatgaaattc atcattttaa agaggatatt ggggctgaca
     6241 gcacttttct aaacaaaaaa cagacttaca actacctagg tatctctaat aatacacttg
     6301 atattgggat tgcaatggga ttaccctata tccgaatcgg aaaatctatt agtttcaaca
     6361 agaaaagtat caatcaatgg atgacaagat tagaaatcag cgcataagga ggtaaatatg
     6421 tctattaaga aaacaaaaaa tggaacatat caattacgac tttacattcc agaagatgtt
     6481 caagcaaaat tgggtttagg taaacttttt gaaagaaaat ataaaaccag acgagaagcc
     6541 aaagaagtag aattaaaact ttctatcgac attaaaaatg ctaagtctgg aaaaagccat
     6601 ataaacataa aaaataaagg agaaatcata ttcaaaaaat tttatgaaga tatttggctc
     6661 gaaccataca aagcaggtca aaccacaaca acaataaaac cacccacaaa agcaacagtt
     6721 ttccaaacag aaaatatatt caggctacac attttaccca ttctgggtaa atattctatc
     6781 gaatacccaa ataataataa acaacttatt ctttcattac ttactcccaa agcaaatagc
     6841 tatgctaatt tcaaagtaat taggagctat gttaattctg ttttcgattg ggctgaggaa
     6901 ctagaatata ttccatcaaa taaactccgc aaaacaatta ctagaattaa agctaataaa
     6961 aagattctcc ttaaagaaag caaacgagag gaagatttat ctctcgataa agaagagctg
     7021 aaattatggt tacaagcttt tgacatagac ttagagaaag gacttattga tttaaaagac
     7081 tacactctct tttatacgac attcttttta tccgatagaa aatcagaaag ttatgctctt
     7141 caatggaaac acatcaattt ctctactgga gaaacactga tagaacaagc tttagatcgt
     7201 ttcggaaata taaaacccac caaaggtcgt aagaagaccc tttttaaaac acctattgaa
     7261 ttaattgagc tattagctaa ttggaaagca agacaacaag aggagttaaa attatttgga
     7321 ttgcgtcaaa ctcaaaagca gtttgtattc acctataatg atcgttcaaa caacattaat
     7381 ttacctcttc acgtggatta tctaaattat agaatgaagt cagtcagacg gagacatcca
     7441 gaacttgcac cagcatcacc acacaaacta agacatgcag gtgttactct tgccaaacaa
     7501 gcaggttatt ctcttgaagc tatttcagaa gctctaactc atagtgataa gcaaattaca
     7561 aagacttatg taaatacaaa agatatagtt aatcggacag taggcgatat tgcatttcgt
     7621 agcttgaaaa aataatggtg gaaaattggt ggaaactttg gtggaaacta tcgaattttg
     7681 aataaaaaaa gacacccaag agataactct tgaatgtctt gaaacattga tataatcgta
     7741 ttgattaacg ttttgagaat tgtgaagctt tacgagcttt cttaagatct ggttttaaac
     7801 caatgaattt caatataact taataggtag aaactacagg caactaggcc ttttcttttg
     7861 tccagaattt caaaaagttt gagatttttt gaggaaaaca ggggaaattc acttactgcg
     7921 ttttactccg aactactgca ctcttctgca ctccagttat aaatagatcc gctattctgc
     7981 caaagtatag tactgatttc tatcttgctt acttgtgcca tgccattcca ggatctcttt
     8041 atttacaaga ctctttaata atttacttgc aaaatttcta cccctatttg ttattctagc
     8101 ggccaaagca gtagtcattt tctctccggt attatacatg atatgtaaaa ttgctttctc
     8161 atcgtcattt aaatcattga attcgtcata ttttttcatc atcttatcat taactctcaa
     8221 atgtcggctc aaaatattat tttcaagagt taaaacaact ttatttcctg gctctgtgta
     8281 tttaggttca tgcaagaaat aagattccat ctcagaatag attcgcttca ctccctcatt
     8341 catttctcgt acccatccaa attctgttaa agttctagca atacgaggat tacgagaaaa
     8401 acgttcgtgc ttaatatttt caaccgttac gatattagga agcttacctg gactataaat
     8461 ttctaatcga tcatcaaaca tcataattcg gatataatcg ccaaaaatgg agcaatttct
     8521 atgagttacc gcatttacat cccttcaaac caagcaaatt ctggatactc tggtaatgtt
     8581 ttaaattgcc catcatccaa atattgaaat tctctaagct gagtacgaac aaaatctcga
     8641 actttagtac tcaatcttga aaataggttt tcatagtaga aaatttggaa aactataatc
     8701 atttaactaa tttaaaattc cctttctatg tgatttgaac tttttaatgt atataaaatt
     8761 gccacaaaaa caactgctat atatattaat gcgatataac catacggtaa gtaaatcact
     8821 aatgtagaaa acaataacct tgacacaata tcccctattt ggaaatatgt caccattcct
     8881 ccaaatattg tagccaactt cgtctcatca atattattaa atatgatagt ccccatttta
     8941 ggatttaatg cactaactaa tacactcgaa agaaatgatg ataatataat taaataaata
     9001 ttttggaagt aaaaagcaac gaatgatagt aaaacaatcg ttaaattcat ttttagcaaa
     9061 gtgcctatgg aaaggctttt aaatttttta ctaattagaa ttaaagtgcc cccaagtatt
     9121 cctcctgaaa cagtgctaat tcctaaaagc gagatcgtaa tcgcagaatt aacaattgtc
     9181 aaattagaat ctttagaaag attaacaaca actaatggaa tgagaattgc caaactccca
     9241 ttgagaatag gtataacaag taaagcttcc ttcatgtttc cgatactaaa tagatggtta
     9301 atcgagagct ttaaatttga aataatctca gaaaatgaag ctttaaagtc aaattgagat
     9361 atcttactag tcgaaatcgt ctcgtcataa tagctattaa tttgatttct gattgctaac
     9421 ataattaaca gactaatagc aaaagttaga gaatttataa aagctaagtg agaaaaacta
     9481 aaaaaagtaa ttaaaaacgc ccccaatgat tgatttacaa tattcatcgt agaaacaaca
     9541 gtctgcctaa acgccatagt ttcttctcta tctgactttt tcactattcg attagaaatt
     9601 ggataaaaaa gaccattttc aaattgtccc aatgtatctg caacaagatt aacgagacta
     9661 gcaattatga ctactataat agaaggttta aaattcatag ccacagcaac caataaatat
     9721 agaatcaccc gtagccataa cgttttaata atcattttca ctttattaag cgttttatct
     9781 gcaatgatac caaaaaatat tgtaaataaa ataggtagag tttccgatat atttacgatt
     9841 gaaatagcta aattactctc cttaatctcc gtaacatagg tcatgagagc tataaaatat
     9901 aatgtatctc caaaatttga tatcaaatcc gaaaccagaa cttttagata tagtttgttt
     9961 tttaagattt ttctcatact tctcctttaa cttaaaaact tcactgcata aacagcattc
    10021 tatccaatgg gtaggcattt ccagtccttt gtgccattag agttataact atccctgaaa
    10081 caccatttag caatccaaag tcaatataat caataacttc atcaaaggtt acgcctctaa
    10141 aatatatgtc acgctccaca aatatatact cagaattaga agcatcattt ataatttctt
    10201 taaataaatt atcagaaatt gctttaaatt gtgtctttcc tgtatctaaa tacatcaaat
    10261 tgaacaaaag cattattcca gaccgtccat gacaaattcc attatttaaa atctcactgc
    10321 tattaaggta atcaatagat gaagtaaata catccatcgc catttctcgt aatttctgac
    10381 tatcaatgat tttcgctata ttatatagta ctcttgccat tccaagactg ccatagcacc
    10441 aacttatatt aaatctaaat tcctcattct cctcataatc actgactcta ccattccaac
    10501 caattatttt tccaattgta ttggtaaaaa aggcgttctc atagtaactc aagccctttt
    10561 ctattgaagg tatgtgtttt gttatattaa atttttcaaa tcctaacgcc aacacgtata
    10621 gtggtcccaa tataccgtga gctacaccta gattaatata gccactagga aatcttttcc
    10681 ttaatttttc atttggcata tattccacat aaatagttgg ctcgttaatt attaggtctg
    10741 caaagtaatt taatatttct tttactaata actcttgttc agaagttgat tcctctttgc
    10801 taagcaaata tctagctaca ctagagacac cttgaattac atcaaagtat tcttctttaa
    10861 caatattaga gctttttatt tcacgtagcc tatcttttgt taaagctaat aaaattgtct
    10921 caagtgtatc tagtaattta tcatatcctt tacaattttt agataaaaat tccaaggcat
    10981 atacatagcc cgtaaatcca tagcaaagtg aaatattatt agtgctattc aatttaatag
    11041 actttagcaa ttcttgtaga taataattta ctctattata gagaagctta gaatactcct
    11101 tattatcaca atttatcaac ctataggata aatatataat tatacttgga tattctgata
    11161 agtaacttct attttctgta taatatgctc tctgcaatct gtcaataata tcactatcca
    11221 acacgagttt atctacttta cagataattt cttcatactt tttaagtaaa ttccttataa
    11281 ttattcaacg gctctgcaat atacatgata aaataaagat attccttttc tctatatgga
    11341 aacatgccta ctctattcat atgcatatga agtaaactat agactatatc atttttacct
    11401 tcaaaatatc catcaatagg cgggaactct ctaaatactt cattaaaaat ttcaaactga
    11461 tttttgtaat caaaatattc tttgaattcc tttactacta ttgtgttatt tgggaataac
    11521 tttttaaaac ttttacgata tctattttga gtcaaattcc ccttcagcaa ctcaagtaat
    11581 cgctttaatg ggatccctaa taatcgaata tataaaaatg tcgaatgcaa aacagaaaat
    11641 aaatctttat catttaataa tttcttcgaa aataacttta gggtaagaaa actgtcaata
    11701 gaaaacatcc tctcacaaac tgttataaag ttatctccac catatctctc aatttccctc
    11761 tcatataaat taaaactaac atcattacaa aaaccacttt ctagtaggaa gtctatccaa
    11821 tgtgcaattc gaaatcttaa atcttcaaaa ttatcatcgt tatttatttt aaatcgtaat
    11881 cgaagcgatc cattatcctt atcgctataa tttacaaaat gaaaatcact aattagcttt
    11941 tcaaccaata gctcgtctgt aaacaaaaga agccgctctc ttagttcaag tagaattgat
    12001 gaattaattc catataatct aaaatagatc caatcactcg aaaatgtttt aacatagttc
    12061 ttataaaagt tatttgtcaa tcttctaaca gatttttcct gcatagaata atgatttata
    12121 ctactttgat aattttcaaa tccaaagata aactcacaat ttttaccatc atatttttca
    12181 aaacgtgtaa aatacagttt atccacattt tgttttaaaa gccactgtgt atctaaatca
    12241 ttctctaaat cgaccaatag acgctcatca gctttatgaa aatacagtag tctaggtaca
    12301 tcaaaatctt ttttccactg tttaatagaa gataaatcat ttttatctat atctgacaaa
    12361 acccacttct cttcacttaa aattatattt ccatatttaa ttttgggaat atagggaaga
    12421 taatcaaaat tttcaattat cctaaacact gaaaacggat tatcttgcca ttctaaagaa
    12481 accgctagca aaaatcttgc taaatcgcta aatactccat ttgatttatg atttagcatt
    12541 gatgttgtta caaaattaac aattgagccg gttcgtaaat ccctaaaata taatttatat
    12601 cgatattctg tttttataac ccccaccacc acagaatcta attcaatcga tgtgttatca
    12661 ttgtcatcat aagataataa taacttttta gaatgagcat tctgtgccga cataacattt
    12721 aaattcttac tatctcttgg aaattctatt aattctacat tatccaactg tgaatctaac
    12781 gagatataag aattaggaaa ataggaggca aaccttccaa tagacttccc tatcatgtca
    12841 ctccctgtat ttgggacaac tgatataaca ggttgagatt caaaattctt aatttcacaa
    12901 tataactcta actgatttgc aacaaatcta tccgaatttg ggtataacaa tcctaaaggt
    12961 atatttgata tatctatctc ttttttacaa tttttaacag ctttgaagac ttctttactc
    13021 agataagaca aaaaattttg ctcttctaca ctacttgatg actttacatg agttcccaaa
    13081 gtttgttttg gtaaacccag tcctaaatta ccatctaata attctttaat tggaacttct
    13141 acgtattctc catatttttc aacaaatttt tctgtaaatg attctaattc tctgtttcga
    13201 taacctttag ccagattaat ttttgaaata aaattaacaa aatcctccat tttctttttt
    13261 aaatttttgg gcagcaccga atcacaacaa tttactaaat ccaccttcag gtaatgctgt
    13321 tttttatcat taaaaatata cgacattttt ttacaaattt cagtatattg agaaatgcct
    13381 tctcccaact ctaattttgc atactgctca atactatttt ttatttgtaa taaatcctcg
    13441 gttaattttc tttggttatt aatatccttt aaaatgttgg ttaaatcatc taaatcttta
    13501 tggcttattg caacttttcg caagtttgta aacaaaaatt cattagtaat caaattacgt
    13561 atataatcta aaattttctg cttctctaaa tcaggagatt tactttgaag taccagttct
    13621 aacacactga cttccgattt atacgttaat ttttgtatga attctaaaag tccagttttc
    13681 ttgataaata aatccttact tatctcagag attccccagt aattgacatt acttaattga
    13741 tacttatctg ataattcaag tactttttgg ttccactata tatgtagttg taataagaca
    13801 gaatctttat tttctaacat catacaaatc gaacttagcc actctccact aaccgagatt
    13861 tttttcgtat aattttctcc aatcttttga tgatatgaga tatcagaaaa agttcctaca
    13921 ccaattgaac taaacaatcc aaacggcgtt gctcttgtaa ttgatctttt tacatagttt
    13981 ctaaaggtgg aatttttata tattttttct ttagttaaat tatggaaaaa ttgagggttc
    14041 gccactagca acatttcttt aaaaactttg ttatcaaaaa atatttcaag attattttca
    14101 ctaagttttt ctataagtct tgaatcatta acgcattacc tataaatgta attatctttt
    14161 atcttaaaca taattctctt gtaaaaaaag gtaagtacct cgtatacctg ccttattcaa
    14221 tcaattataa aactaatctt tacaacaacc tgtagatgtt acaccaccag aaacataacc
    14281 ttgttctgtt gaaacttcag ttacatcaag ttccaatgaa aattcagtat tttccatgat
    14341 aactctgcct cttctttaag ttgtgtttat aatactaaaa gcaaatttat ttgtcaataa
    14401 tttttagaaa attcattctt tttgtttcgg agtattataa aataaaatcc gtctgtacta
    14461 tcaaacaagc tctgttatca gaagatattt cataagaaat ccttaacaga tgtcattaca
    14521 tttttgaaaa ctagaatcat tatcaaaaaa gcaaacaagt tgacaattca ggactagaaa
    14581 aacgtattat ttgagaggta taaaatttcc aataataatt ctcactactc gtggatcctc
    14641 gtcataagaa ataaagatat ccttatactt tagacgtaga ccctctgctt caagatatac
    14701 tcgcttaatg tatgtttgac tattacatac cacagcatat acggcaccat catagtcaaa
    14761 acctgtttca cgaatgagag caactgaacc attgtgatac tttggctcca tagaatctcc
    14821 agacacccat gaggcaaagt catgcgccaa ctcctccgta aagtaaaccg tttcataata
    14881 aggaattaaa actatttggt ttacaccaga ctcaaaagca gtttgtgttt acctataatg
    14941 accgatccaa taatatcaac cttccacttc atacagatta cctcaactat agaatgaatt
    15001 ctgtcagacg taggcatcca gaactatccc ctgcttcacc acataagtta agacacacag
    15061 gtgccactct tgcaagaaaa tctggcgttc ccctagaaat tatttccgag gcattaactc
    15121 atagtgataa acaaattaca aagacctatg ttaacacaaa aatatagtaa atcaaactgc
    15181 tggagatatt gcatatagaa gcttaaaaaa atggctctat aatttctgta gtgggtaaat
    15241 cctctatgga gattatggag ccttttt
//
