LOCUS       c00014_JAIQWO0..       17346 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIQWO010000022.1 Streptococcus thermophilus strain CF8_14
            NODE_22_length_34630_cov_21.686652, whole genome shotgun sequence.
ACCESSION   JAIQWO010000022
VERSION     JAIQWO010000022
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:24:38
            Original ID  :: JAIQWO010000022.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17346
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17346
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4921:7346]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4922..7346
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..17346
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17346
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             2..340
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 106; E-value:
                     4.3e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="KKQNLTEQKLHELLSDLGLLELLKKYPNQLSGGQKQRVAIARALY
                     TDPDYILADEPTAALDTDRSMKVIELLRDLAHKRNKIIIVVTHDFRLKDMADKVYQIID
                     GKMTILEK"
     CDS             812..913
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MEEVRKLRQEKAELEKENDFLKKAAAFFAKEID"
     CDS             1083..1352
                     /locus_tag="ctg14_3"
                     /transl_table=11
                     /translation="VQWKEVNQFFETESIKLSDIEPSKVSYREVQRNQINTTIYNEKGN
                     IKDIDTSIIRDMYDKSKPTLKQGAYISAIAASLEGGYCIYNSNN"
     CDS             1512..1811
                     /locus_tag="ctg14_4"
                     /transl_table=11
                     /translation="LCTASFGIAKEAYKFRKNLITKEEFLLNSQILCVEVSVSALSSIL
                     GHAVIPIPILGSVIGNNIGTFLYEIAKDNLTMKEKLLIADYFKEIQEYNYFLDN"
     CDS             complement(1911..2822)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 99; E-value: 4.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_5"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNS"
     CDS             complement(3052..3141)
                     /locus_tag="ctg14_6"
                     /transl_table=11
                     /translation="MKEHFVIRGKRDFIVNKVADEYIGYDLLD"
     CDS             complement(3138..3749)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_7"
                     /sec_met_domain="TIGR04085 (E-value: 6.3e-16, bitscore:
                     49.7, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.8e-13, bitscore: 41.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNDMLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERIS
                     KGEFKVKFKIVPPNESDVFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAGV
                     RACSINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLRSITFDDISGKCS
                     ECPLPWCGGGCRCSALKLDGTLLGSDLACFYEQKGGGVVV"
     CDS             complement(3834..4925)
                     /locus_tag="ctg14_8"
                     /transl_table=11
                     /translation="MSKKIFNLYGMNMFLSGLPYYFVGILLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSYISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESL
                     SSGVLISYNFEIIDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVF
                     VIFSLLYLIGLPEIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLL
                     MRVLNSNYNNHFYYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNY
                     LIFGIVALCCLVSYSFSNREKRT"
     CDS             complement(4922..6241)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_9"
                     /sec_met_domain="PF04055 (E-value: 2.5e-20, bitscore: 64.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.5e-07, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.2e-14, bitscore:
                     43.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 5.1e-25, bitscore:
                     79.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEIATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQNARKHVAKLKKHNILS
                     FPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGEPT
                     RYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDPKLNFEL
                     MGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEV
                     TGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEF
                     GEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSF
                     RTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             complement(6311..6403)
                     /locus_tag="ctg14_10"
                     /transl_table=11
                     /translation="MSKELEKVLESSSMAKGDGWKVMAKGDGWE"
     CDS             complement(6486..7346)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_11"
                     /sec_met_domain="TIGR01716 (E-value: 2.6e-51, bitscore:
                     165.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGEIFKKFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMELED
                     RREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYYELLIFSNTLDVL
                     NHDVFMVLAREMFRRSDFYKEIPNNRRLISTMLLNGYITCVEREKFMDALYFEKQLNQC
                     FFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSHHLAKTYEGHLEK
                     ILASS"
     CDS             complement(7586..8422)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 266.7; E-value: 3.2e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg14_12"
                     /transl_table=11
                     /translation="LVTEFSLDMLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIF
                     TEHKGNYGYRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAE
                     NLIQRQFEASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQV
                     KAMLEQAFTEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESF
                     FGILKSEMFYGYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             complement(8416..8982)
                     /locus_tag="ctg14_13"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYTIVEKTRGRLSKMGRKPKKKLEEMERLQAENEYLRAENAV
                     LKKLRELRLREEKEQEEKRKLSEDW"
     CDS             complement(9161..9319)
                     /locus_tag="ctg14_14"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             complement(9640..10104)
                     /locus_tag="ctg14_15"
                     /transl_table=11
                     /translation="VKSLSISSSFFSISTSSTPQLTANSIGQHSTAKQSRKEIELAAAK
                     LVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTSQNDAM
                     NQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTN"
     CDS             complement(10384..13563)
                     /gene_functions="other (smcogs) SMCOG1218:Exonuclease
                     (Score: 496.3; E-value: 3.2e-150)"
                     /gene_kind="other"
                     /locus_tag="ctg14_16"
                     /transl_table=11
                     /translation="MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFD
                     AMTVALFATTSGDRNVEEMRSTFAGPEDDLTKVTFYFQQGNHLYRIDRVLQQERAKQGG
                     GTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFS
                     RFLKEDSKTKTQILKKIFGTGIFDRFQKSLEERLRQSNKDMDKRQAQIDSHFASQVWSE
                     EELTVLASTPASEKLARLEEFLSQRQESLTEQKSILKAAHEDLAQLQKSFQTAQDLAKI
                     FQELEQAKERYRLEIEEGAQGQAEAKVHLEELQFAQGLQETIRTLKQYRKQLMQLEQDL
                     EIAQEALSEKQQAFEDVKAKKEELAIQSEDFLQKEEELETWKEDIIYSQSLAQEQEKIK
                     RSTTNYKQLEETYQQARKEVEMLNKSLSDLEANRLSLESLHEAEKLFQIVGYSVENQLA
                     QDLKEIENLNQELTKTEKRHQTLSFDIDQAQEILKELEEELRRTLVSRRQLMIVQLQAE
                     LEEGHPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQATLSEV
                     ASKRQDLLDQVTKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQYYQE
                     LQKRYDKEETDYIRYQDELGKAQKKATDLAKTYQEAKAVLDQAQERLEDLQEAHPELES
                     VEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDVKR
                     LSAELEQSLKAEGALANDLEQVELWLIEVNNQAIPMLQAKLTTYATLKQELQAQIRKGQ
                     ELLQNQEQPDLDSLAQAVQNCQEIYDRQLAQFSVMEKGLKDATATYQAAKTLQDSNQEA
                     FKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLTDNRYSFV
                     LSEEGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGA
                     VVEALFIDEGFGSLDKEALTKAISVLEQIGENRMVGVISHVDDMKEGIAQQLVIIKSHD
                     GSSRIKIVDKG"
     CDS             complement(13560..14786)
                     /gene_functions="other (smcogs) SMCOG1230:Nuclease SbcCD, D
                     subunit (Score: 253.8; E-value: 6.2e-77)"
                     /gene_kind="other"
                     /locus_tag="ctg14_17"
                     /transl_table=11
                     /translation="MNEEVVMKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEK
                     VDGVIISGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFF
                     QHQGLHLSTRLEEAFEPIELENCQIFLLPFIDPIDARIYYKDDEGKEIQGIGDALTYIL
                     EDMKKAFDPDKAHVLVTHFAVSKKDDSDGQGLRELMLSETSNTVGGLTNVTSDLFKSFD
                     YVALGHIHTRFASPTKRVQYSGSPVAFNVKEAKRKEEKGVYILELDASGDMSQTFHTLE
                     VKRPIVALQESFETLMSPEFYKNQPCQKAWFAFDIQLSSRKELEGINVRARLEEIYGTD
                     IVEITFSRLGDVREENLTVDQHLKDLEMQSPQEIVFDFYQTVTGGDVLSERQTALVESV
                     FEEIERSRQ"
ORIGIN
        1 aaaaaaacaa aatttgactg aacaaaaatt gcatgagctt ctttctgatt taggactttt
       61 agaactgcta aaaaaatatc ctaatcaact ttctggtgga caaaagcagc gtgtggcaat
      121 tgctagagca ttatacactg atcctgacta tattttagca gatgaaccca cagccgcatt
      181 agatacagat agatccatga aagtaatcga gttactcaga gatttagcgc acaaaagaaa
      241 taaaattatt attgtagtta ctcatgactt taggttaaaa gatatggcag acaaagttta
      301 tcagataatt gacggtaaaa tgacaatcct ggagaagtaa tttaatttat gactaaaaat
      361 cagcaaaaat ataattatga ctaaggaata tattattaac taaatgttga gatagcacaa
      421 ggaaatattt gtgctatctt ttttatttat taggaaaaga gaaaaaatta tgccaacgaa
      481 aatatggtta aaaccagaac aattagattt gtatattaaa catttagaac gatttagaga
      541 cttatatagt aaactagact gttctggtat agtaaatttg taacactcct acctaataag
      601 ttaaactatt cattagaata ggagacataa catgaaacac tatccagacg aaacacgata
      661 aaaaattgtt cgactgcaca ttcaagacgg atgaacatta aaaagcttag ctgctgaata
      721 tggcgtatcc caagcctcaa tctctaattg ggtaagacat tatcgcaaag aatgccaaac
      781 taataataaa gaaaaatcac agcttgaact catggaggag gttcgtaaat tacgtcaaga
      841 aaaggcagag cttgaaaagg aaaatgattt cttaaaaaaa gcagcggcat tctttgcaaa
      901 ggaaatcgat tagaggcata tcgttttatt gataactata aagaagattt tggtttgcgt
      961 tggttgttct tgcatatgaa tattcatccc aatgcttatt ataattatct taaaaagaca
     1021 aggactaact atcatcgtca aaagaaagct attcttaata ctattcgaga tatctaccat
     1081 gagtgcaatg gaaagaagta aatcaattct tcgaaacaga aagcatcaaa ctttctgata
     1141 tagagccttc gaaagttagt tatagggagg tacaaaggaa tcaaatcaat accactattt
     1201 ataatgaaaa aggtaatata aaggatattg atactagcat tataagagat atgtacgata
     1261 aaagcaaacc tactttaaaa cagggagcct atatatccgc tatagcagct tctctagaag
     1321 gggggtactg catttataac agcaataatt aaaaaaagcg cttagggaaa actattagtg
     1381 agtttacaaa agacgattgt cttgaaattt ctaaagatag tggaattgga gctataaaag
     1441 gaagtactcg aggcattacg atatacgccc taacgaatta cacagctact cctgcagcag
     1501 tagcaagttc attgtgcact gcttcatttg gtatcgctaa agaagcatac aaattccgta
     1561 aaaacttaat cacaaaagaa gaatttttac taaattcgca aatattatgt gttgaagtat
     1621 cagttagtgc attatcctca atattaggac atgctgtaat tccaatacct attttaggat
     1681 ccgttattgg aaataatata ggaactttcc tatatgaaat cgctaaagat aatctcacaa
     1741 tgaaagagaa attactgata gcagattatt tcaaagagat acaagaatat aactattttt
     1801 tagataatta atttgaatta tataatcatc aacttcagag agattaagaa ttactataaa
     1861 cttttaggga aggcattttc tcctgactat aatatcgctt ttcagggatc ttatgaattt
     1921 ttaaatatgt tttttaaaaa tacgttaacc tctcctattt tctctgcttc aggtaaatag
     1981 atagaaacgg ttgtcgaata aacaaaagaa ggtacactca caattgaaag caattgacta
     2041 ataactgcat aaatagccaa caattctact cctaatctcg acatcaaggc atcaaacacc
     2101 ataataaaca aaacactctc cagaatttct tgaccaacca aaggaatacc aaatgttatt
     2161 aattcaaatt tagttgtaga tgtaatggat aaagccttca aaatcattgg ataaaccata
     2221 aacaagtaac taagcgatat gaaagctaag gatacaatcg ttgatatggc tgctccctta
     2281 attccgattt gtggtaccag tacataattt aacacaacat ctattaatga actgataagt
     2341 ccaacccaca taattggttt tgttttcttt tgaactctta ataaatttgt cagcgaaaag
     2401 tttaataatg tcaatccgat atatggagac atgaagacta aataaatggt ggataaggac
     2461 aatagttgcc ctttaaatcc atagagctgc ttcaagatta catttccaaa aataatgaca
     2521 aaaaccgcaa aggcaactcc gataattaaa tctaaggtta gatttgattt caataaatca
     2581 tcaaacctgt tagtttgccg attagagtac gccttagagc ttttaatatt aaatgacaaa
     2641 ctgaatgctc ctaaaagtcc accaaaagca aataagagat tctgaataat ggaaattcct
     2701 gacagagcaa ttgaggaatt gttcacagca aaatgcaatg ctatctgccc aataattact
     2761 tgaccaatat ttgttaaaac taagggaaag gcaaatttgt taatttcttt tgaatctatc
     2821 atttttcctc tctaaaaggc ttcaaatgta agtaaagatc agatttaact aaatttgcat
     2881 aaataatatg caaaatagga gtttcttcta aaaatgaaat aattgcctgc ttacaatcat
     2941 tagcagatac ctcataatct tgctgtaata gttctacaat cttgtctaaa gaaaaatttt
     3001 tagaaatgca ataaagtatt tctgctccta tttcatcaaa tgaatagtac tctaatcaag
     3061 tagatcgtat cctatgtatt catctgctac tttatttaca atgaaatctc tcttacctct
     3121 tatcacaaaa tgttctttca tacgactact ccacctcctt tttgttcata aaagcaggct
     3181 aaatcagagc ccagtaacgt tccatctaat ttcaaggcac tgcatcgaca tcccccacca
     3241 caccatggta ggggacattc tgaacatttc ccagaaatat catcaaatgt aattgatctt
     3301 agtttattaa atacagcaga atggtgccaa atttcgctaa acttttgttc tttaacattt
     3361 ccagcaacta attcatctat accattcatc aagtcacacc cgtatacatc tcctttatga
     3421 ttaattgaac atgctctaac tccagcttga caagatattt cccttggctt atcaaaattt
     3481 atatctactt tttgatgcca aacattttct aataaatctg atctattata aaatgcaagc
     3541 ggaaaataat gtgtcaaaaa aacatcactt tcattaggag gaacaatttt aaatttaact
     3601 ttgaactctc ctttagaaat ccgctctgtt aaatcaagaa aaacaggata ccattgtttt
     3661 ttatctgcta aaatactacc gtcattagcc ctaccagtag gacaaataac cataactgac
     3721 atatactcaa taccaagcat atcattcaat cttatactct aaagaaaata tctgctaaat
     3781 ttgcaaacaa ttgtgctatc aataatttgg caaatgaatt agaaatacaa cttttaagtt
     3841 cttttctctc tgttagaaaa tgaataagat actaagcaac aaagagctac tataccaaat
     3901 attaaataat tgctcctaat actaaagtta tcagcaaaaa taccagctag gaaatcagct
     3961 aacataaaac taatcgaaat aaacaaatta tatactgacc atgatactgc tctatttttt
     4021 tctattgaca tattaaattt ataataaaaa tgattattgt agttggaatt aagaacacgc
     4081 attaataaaa ggattataat ttggatgatt agattagttt gaaaaaacat gagtatagct
     4141 aatactggta acatcaagct tacttcaaac ttaattttta gataactccc caaagccata
     4201 gatatattaa acataaatag tataattccc agcatatcta gtgaaagtcc ctgttcattt
     4261 aagaatatcc ctgcataaga attgctaatc ataattagag ttgagaatgc tactcctaat
     4321 attattaata accatggaat attttgaata ttatcgaggc taaaaaattt ttgtttatta
     4381 ttttgttcct ttttaatctc gggtaatcct attaaatata ataaactgaa aattacaaat
     4441 acaatggata taataatagg ataaatataa ttcctatgca ataaaggtgg agatataatc
     4501 gtaataatag caataaaaat atattttaat gtgttgagat ttttcaaaaa tgatttatat
     4561 acaacttcgt catcaattat ttcaaaatta taagaaataa gaactcctga agataatgat
     4621 tctgacaatc caaaaaatat cgctgaaata tatattatat ttgattttcc aaacaatagg
     4681 ccccataatg ctaaaattaa taataaattt gaaatagcca aaattttctt gtaaccaatc
     4741 ttacttgaaa tataacttaa aggaatatca aaaactgagc cacatagctc agtaataact
     4801 gataaagtag ctatttctgt gaacgaaaaa cctaagtgct ttaatagtaa aattcctaca
     4861 aagtagtacg gtaatccaga tagaaacata ttcattccgt ataaattaaa aatcttctta
     4921 ctcataagtt acaaactggg tctctaaaat attttggact cttctcctta atcaagttaa
     4981 catagcagcc accctcgcaa atttttaaca atccacaaga taaacactta gaattcttcg
     5041 ttctaaaaga acgaatccct ccatacaacg gatcatcata ccaaacatct aacaaatctt
     5101 tttcaaaggc attctgctta gtttgattaa ctcctaaaaa agcaatgcaa ggcaagatat
     5161 ccccattaga cattatttcc atcttagtat attttgcacg acatccataa tacatttcgc
     5221 caaactctga aaattcaatt gaattattta tcaactccgg ataagcggtg aaaagatgac
     5281 atccctcagt agcaaaattt aaattagctt cccgttgagt tatataatct gtaacatact
     5341 cattcaacct tctcaaatca gctaaatcgt attttttctt tattttcgta tatcctgtta
     5401 cctcagaata attagctact gaaaatctat ctattttatt ctctatacaa aaatcaacca
     5461 attctataat ctgctcatag ctttgctttg tatacactgc attaattcta catttttttc
     5521 caacctcttt aaagtacttc gctaatttaa tttgtctatc aggtctcacc cccattaatt
     5581 caaaatttaa tttaggatct aaagtctgca aagataaaac cggtgtaata tatttagatt
     5641 tagctagaat ttccactgta cttttcttta ttaattgggc attagttgtt atagtagtct
     5701 ttatcttcag ttcttcacaa gctatcaaca aattatcaat atcaaaatat ctagtcggtt
     5761 cccctcctaa aattgaaaca cttaacactc cattatcttt tgcttggcgc aaaattcttt
     5821 cccaatcttt agcaggtttg gcatttctat cttcacgatt tgctaaaaaa caaaaaccac
     5881 attttaaatc acagtacata ctggggtata ttactagttc aagcggaaaa ctcaatatgt
     5941 tatgtttttt taattttgct acatgctttc tcgcattttg aagagtctcg tcaggatttt
     6001 tcgatgatcc ctcaatatta ttatcagaat agatatttaa taagagtact cgctctagtt
     6061 tccctgcttt tatttctttc ttaaaaaagg acgtagcaat ttcaaaacca tgattttgaa
     6121 ccaaataaag aaaataagct tcactctcat ctaactcaat tcggtcaaaa gttactttat
     6181 ttatcaaaat tccaccaaac ttttctagtc taaataaaaa atcttctgaa attgtcatca
     6241 tattgaatac ctttctaaaa aagcagagga aaatatagcc tctgcttaac ttatgggata
     6301 aattacttta tcactcccag ccgtcacctt ttgccatcac cttccagccg tcaccttttg
     6361 ccattgaact agactcaagg actttttcaa gctctttaga catatttggt actcctttcg
     6421 aatatgatac tgtgattata tttcttttca acacttacaa taaaatattc ccatatttgc
     6481 attttctaac tactagctaa aattttttct aaatgtcctt cataagtctt tgctaagtga
     6541 tgacttcctg ctaatttcat cgctccaaca cacttcttca tttcaataat tgctttcaca
     6601 tttccatcct ctttatattg ataaagattt tgtgcatact taaagactaa acgttcatat
     6661 acttctgtct caataaaaaa gcattgattt agctgctttt caaaatataa agcatccata
     6721 aatttttctc tttcaacaca tgtaatatat ccatttaaaa gcatcgttga aattaatcgt
     6781 ctgttatttg gaatttcttt gtaaaaatca gaacgcctaa acatttctct tgctaagacc
     6841 atgaaaacat catgatttaa tacatctaaa gtattcgaga aaatcaataa ctcatagtac
     6901 ccccagtatt ctacactaaa gagataatct gttaaatatg tcaaatcatc ctttgtatag
     6961 taagtttctc ctgataaatc ctgtagacga attttcaata aaataatatt gatttgatga
     7021 aatttttctc gcctatcttc cagttccatc tgagaataaa gtaatttttt cataccttct
     7081 acgtcacgtg ttgacacaaa atgacgtact ttcgataaca gttcgtttaa ctcatctcta
     7141 tgaaaatcat ggaccgcata cataaattca tctattggca tattgatttc atctaaaata
     7201 aacatgaact ttgaaatcgt taaatctgtt tctcctttct caaatcgaga gagctgagac
     7261 gttgatatac cagcctttgc gacgtctttt aatcgtaatc ctctcgattc tcgaaacttt
     7321 ttaaaaattt ctccaaattt tttcatacta cacctccatc acgcatatat gggaataatt
     7381 ttcatttgct ttcatcatat catacaataa agaaaaacaa aagtgaggat tatcacatga
     7441 aaaagcaaat tttactaaca cttcttcttg tcgtatttga aggcattatc gttatcgtcg
     7501 tgggataaag agtctgggac aaaagtcctt tagctccaaa aagcaacggc ataatgtact
     7561 gaccccaaaa agttagacaa ataatttaag taaaggattt agttctgtat tgtacaggac
     7621 tgagtccttt tagttttacc ttaatgcgtt tgttgttgta ataattaata tagtctgcaa
     7681 ttgcttgttc caaatgctca attgacttaa acgtcttctc ataaccataa aacatctcag
     7741 acttaagaat gccaaagaag gattccatca tgccgttgtc tggactattg cctttacgtg
     7801 acatggatgg ttggattcct ttctcctcta aaaaatgatg atagaaatca tgttgatatt
     7861 gccatccctg gtcactatgg agaattgtat ttttgtaatg tttctctgta aaggcttgtt
     7921 ctaacatagc tttcacttgt atcaagttcg gtgacttaga aagattgtag gcgataattt
     7981 cactattgaa gccatctaaa attggcgaca aatagagttt ttggctgctt gctggaatgg
     8041 caaattctgt tacatctgtg tagcattttt ccaatggttt ggatgcttcg aactggcgtt
     8101 ggatgagatt ctctgctttc ataccaacct ctccttgata tgaagaatac ttacgtttac
     8161 ggcgaattct agcggttaaa ccaagtactt tcataagacg ttgaactctc ttatgattaa
     8221 tcacaattcc tcgatttctc aattcaagag tcattcgacg atagccgtaa tttcctttat
     8281 gctcagtaaa aatggcttga atttcagctt taatgtcata atccttatca ttttgatcca
     8341 gctgttttaa gtggtaataa taggttgaac gagcaagctt aataatcttt agaagcatat
     8401 ctaaagaaaa ctcagttacc aatcctcgga caatttccgt ttttcttctt gctctttttc
     8461 ttccctcaat cggagttctc tcaacttttt aagaactgca ttctccgctc taaggtactc
     8521 attttctgct tgaagacgtt ccatttcttc cagttttttc tttggcttac gtcccatttt
     8581 agataacctt cctcttgttt tctcaacaat agtatacccg tttttcttat agtgtgcgag
     8641 ccagttagga agcgtcccac gatttgggag agcatattca agagaaactc tatcttgaga
     8701 atagccttta tataggactt tatcaatcat ttcttgtttt aattcaggag agtagtaacg
     8761 attctttcct tttttagcga tttctattcc gtatcgatca atcaatttaa tcatgtagct
     8821 aagattagaa atgtttatcc caaatttatt tgaaagctga tctaagctat atccttggtt
     8881 tctaagttca tagatttgaa ccttatcttc ataagtcaat ttcataataa aaacaccccg
     8941 aaagttagat tttttctgtc taacttttgg ggtgcagttc ataaaaccgt tgctttttgc
     9001 atgattgtga tagacttggt gaaatagaat tgaccaaaaa tcttctgaaa tataacaaga
     9061 gagtgactcg aatttaaaaa gctagagttc cacaattgga aatctctagc ttttttgtga
     9121 ctgagaactt tttgtcccag cctctacttt ctactgacta ctatcctgca tgccctaagt
     9181 cgagatagag aatatctcgc ttagtggcat actctagcgc atgttcaaca gcctcaaata
     9241 aatctgaagc tagaaacctt ttcgtaaaga cggtttcgtc tttacgctta aatttcgcaa
     9301 cataactatg tttagtcatt ttttctcctt ctaatattca tattgtcctt taacaccact
     9361 atagatccag taaactgctt tatcataaac ttgtttaaag gagataccta atcgattggc
     9421 tacatcaaga attgaaattt gcttacattc ctctatattc ataaaatatc atcattttgt
     9481 cgtagtattc ggcaatgatg gaacagatga ggattcttct aaagttttag gagttgcctt
     9541 atctagatca tctaacccag atttccaaac ctgtacttgg ttgaccaata acttaccagg
     9601 tagtttcgaa tagttcaaat taaccgttct ggtttctgtt tagtttgtct ttgattggtt
     9661 ggcattcttt aaatcagata cataagttac attataagag accatggcaa tggcttgatt
     9721 cgtagtctga ttgacaaaga tatctgcttt ttcaaaatga taatccaaaa tatagtcctt
     9781 atacacttgg ttcatggcat cattttgact tgtcaattct tgagaatagg ccgattcagt
     9841 catataaggt tgaatacgtg tattattttc ccctagtttt tctttcgtat agtactgtgt
     9901 caaaaattct tttacagtat ctgatgataa aatacttgct ttatcttctg cttgtttgtc
     9961 ctctacaagt ttagctgcag ccaattcgat ttcttttcga ctttgtttgg cagtagaatg
    10021 ttgaccaata gaattagcag taagttgtgg tgttgatgag gtggatatac taaaaaatga
    10081 ggaggaaatt gataatgact tcacctagct aaaagttcaa cgaattaggg agacattagg
    10141 tagcctcata ttaccttgat tagtttttgc tataacattg tcaaatatga tgacaaaaaa
    10201 atccgtccgc acttttttac gagtaggacg aattaaatat gttatacaaa ccatcagctt
    10261 tttaacaatt ctacataagg tagttgttaa tgcaactacc ttttttctat gttgattaga
    10321 acaaatttga catggctaca actgcgatta tctgatatag agtattatat aaactgattc
    10381 ctcctacccc ttatccacaa ttttaatacg gctactgcca tcgtgcgact tgatgataac
    10441 tagttgctga gcaatacctt ctttcatatc gtccacgtgg ctgatgacac cgaccatgcg
    10501 attttcaccg atttgttcta ggacagagat agccttagtg agggcttcct tatcaagtga
    10561 accgaaacct tcgtcgatga agagtgcttc aacaacggca cccttgctgg tattttggac
    10621 aacttctgag agggataggg caatggccag tgcagcgata aaggtttcac caccagacaa
    10681 ggatttaacg gagcgttcac tacctgtcag ctggtcatag acgttgatat ccaaaccgaa
    10741 gtgatcacgc gccctgcgtc cttcctcact tagaacaaag gaatagcggt tatccgttaa
    10801 tagtccgatg tagttagcat tggcatagtc caagatttgt tggaaatact gacggataac
    10861 gtagacctca agattaagac gaccagttag agcagtattt tctcccttaa ccaccttaac
    10921 caaatcactg agttcttggt gggccttaaa ggcctcttgg ttgctgtctt gaagggtttt
    10981 agccgcttgg taggtagccg tcgcatcctt aagtcccttt tccatgacag aaaactgagc
    11041 gagctgccta tcatagattt cctgacaatt ctgtactgct tgcgctagac tatcgagatc
    11101 tggttgttct tgattttgga gaagctcttg ccccttacga atctgcgcct gtaattcttg
    11161 tttgagcgtt gcataggtcg ttaatttggc ctgaagcata ggaatagctt gattatttac
    11221 ctcaataagc cagagttcga cctgctctaa gtcattggcg agggctcctt cagccttgag
    11281 actttgctct aattcagcag ataatcgctt aacatcttga tttaccttat ctttagactt
    11341 agttatactc tcaatctgcc ccttgattcc tttaatgtcg gcatgaagtt ggttgtaggc
    11401 ttcgctattt tccttgactt gcttattgta gaggttcagc tcctgatgag caagggaaat
    11461 ccgttcttga tatacctcaa cagactcaag ttctggatga gcttcctgca agtcctctag
    11521 gcgttcttga gcttggtcaa gcactgcctt ggcctcttga taggttttag ccaaatctgt
    11581 cgcttttttt tgagccttac ctagctcatc ttgatatcgg atataatctg tctcttcctt
    11641 atcataacgt ttttgtaact cttgataata ctgctcaacc ttcaggagta gggcttgccc
    11701 acggtcagtt tcatagtcta tcgaaaaatc aaaatcaaac cgtcccttaa cgtgctcttc
    11761 taattcttga tagtgctttt caagagttgc cttgacttta gtcacttggt caagcaaatc
    11821 ctgacgttta gatgcaactt cactcaaggt agcctgacga tttgataaag tagcgacttg
    11881 cttttctttt tgagcttgaa gcttctccac ctgatccatg agatttttca aggccacttc
    11941 atcagcctgt gctccaccaa cattagggtg ttccagagca ccacaaacca tacaaggatg
    12001 cccctcctct aactctgcct gcagttggac aatcatgagt tgacggcgtg aaaccaaagt
    12061 ccttcttaac tcctcttcca attctttgag aatttcttga gcttgatcaa tatcaaaaga
    12121 taacgtttga tgacgttttt cggtctttgt caactcctga ttcaagttct ctatctcttt
    12181 caggtcctga gcaagttgat tctccacact gtagcccaca atctggaaga gtttttcggc
    12241 ctcatgtaaa ctctctaaac taagacgatt agcctccaag tcagacaagg acttgttaag
    12301 catctcaacc tcttttctag cctgctgata ggtctcttcc aactgcttgt agttagtcgt
    12361 tgaacgtttg attttctcct gttcttgggc aagactctgg gaatagataa tatcctcttt
    12421 ccaagtttca agctcctctt ctttttgaag aaaatcctca gattgaattg cgagttcctc
    12481 ttttttagcc ttaacatcct caaacgcctg ttgcttttca cttaaggctt cttgagcaat
    12541 ttcaaggtcc tgctctaatt gcatcaactg tttccgatac tgcttcaagg tccgaatggt
    12601 ttcctgcaga ccttgagcaa actgtaattc ctccagatgc acttttgcct ctgcctgtcc
    12661 ttgagccccc tcctcaattt ccagacggta acgttccttg gcttgctcca attcttgaaa
    12721 aatctttgcc aaatcttggg cagtttggaa gctcttctgc agttgtgcca aatcctcgtg
    12781 ggcagccttc aagatacttt tttgctccgt aagactttct tgacgctgag acaaaaactc
    12841 ttcaagacgt gccaattttt cagaggctgg cgttgacgcc aagacagtta attcttcctc
    12901 cgaccaaacc tgactggcaa agtggctatc tatctgagcc tgacgcttat ccatatcctt
    12961 attgctctga cgaagacgct cttccaaact cttttgaaaa cggtcaaaga tacctgtccc
    13021 aaagattttc tttaaaattt gagtcttagt cttggaatct tccttcaaaa aacggctaaa
    13081 atcattttgc ggtaagagga taatctgttt gaactgctca gcattgagcc ccaaaatctg
    13141 ctcaatctgg tcactcactt ccttgatctt atccccaagc ttttcaattt cctgaccacc
    13201 aatcttatcc acaatgacta gagaagccgt cgccttttgc atggtagtgc ccccaccctg
    13261 cttggccctc tcttgctgga gaactcggtc aatgcgataa aggtgattgc cttgttggaa
    13321 atagaaagtc accttggtca aatcatcctc tggaccagcg aaagttgacc gcatctcctc
    13381 aacattacga tcaccactgg tcgtagcaaa caaggctacc gtcatggcat caaagagagt
    13441 actcttacca gcccctgtat cccctccaat caaaaagagg ggagcatggt caaactgagt
    13501 gaaattaata acttccttac gatatggtcc aaaattggtc aattctaact ggactggtct
    13561 cattgtcgac tcctctcaat ctcctcaaaa acactttcca caagggcagt ctgtctctca
    13621 gataagacat cgcccccagt tactgtctgg taaaaatcaa atacgatttc ctggggcgac
    13681 tgcatttcca aatcttttaa gtgctgatca acggtcaagt tttcttccct aacatcaccc
    13741 agacgactga aagtaatttc tacaatgtct gtcccataaa tctcttccag tcgggcacgc
    13801 acattgatac cctctaattc cttacgacta gacagttgaa tatcaaaggc gaaccaggct
    13861 ttttgacaag gttgattctt ataaaattca ggtgacatca aggtttcaaa agattcctgt
    13921 aaagccacaa tcggccgttt aacctctaga gtatggaagg tctgagacat atcaccagac
    13981 gcatccaatt caagaatata gacacccttt tcttccttac gcttggcttc tttgacatta
    14041 aaggcgactg gactgcctga atattgcacg cgcttggtag gactagcaaa acgcgtatgg
    14101 atatgcccta aggcaacata atcgaaagac ttgaaaaggt cactggtcac attggtaaga
    14161 ccacctaccg tattactggt ttcagacaac atcaattctc gaagaccctg accatcgcta
    14221 tcatccttct tagaaaccgc aaaatgcgtc accaagacat gagctttgtc aggatcaaaa
    14281 gcttttttca tatcctcaag aatgtaggtc aaggcatcac caatcccctg aatttccttt
    14341 ccctcatcat ccttatagta aatacgagca tcaataggat cgataaaagg cagcagaaaa
    14401 atctggcaat tctccaactc aatgggctca aaagcctcct ccaaacgtgt acttaaatga
    14461 aggccctgat gttgaaagaa gtcacgccca aaatgtaaac gttcagcccc atcgtgatta
    14521 ccactaatcg catagacagg aatctgctcc tccagtacca agcgggccaa ggtcttatta
    14581 aaaagcttaa tcgcatccac agggggcacc gcacggtcat agaggtcccc agaaatgata
    14641 accccatcca ctttttcgct aatagccaaa tccacaattt gttgaaaagc ccactcctgc
    14701 tcctccaaca aagaccagcc attgagggtt cgtcctacat gccaatctga cgtatgtaaa
    14761 aacttcatga caacctcctc attcattttg tcttacttct attgtacctt atcaagctaa
    14821 atactgctta aaagtttcac aggctttgat agttttcccg ttttttagct gtaaagatca
    14881 aaaaatctct cccaagctat cctgtactga ccccaaaaag ttagacaatt tatgtaagca
    14941 aaggatttag ctctgtattg cacaggattg agtcctttta gttttacctt aatgcatttg
    15001 ttgttgtagt aatcaatata gtctagatta ccctgcctca attggttaag taatttaaat
    15061 acctctaacc aagaaaatca atattatcta ttcttttaat tgacttttat agattctaag
    15121 cattatcata taggttggta ctagtgcaca tcttgtattt taggcaataa tatttactca
    15181 cttttcgtta ttgtcagtac cgatcctttt taaatttttc accatgaaaa cctaaaaata
    15241 atccgaaccc taagggctcc tgacttttta ctttattcta ggcttttttt atccgtagct
    15301 tgttagctga cttggaacta ggcatgtagt atttactatt tccctacttg agatttttta
    15361 taagtcacat gcattattcc atctgaacga atggtatgat ttttatttct tttagagaaa
    15421 caccggtaat agctaattcc tatcttaaat cacttgaaat atatttataa tgtgttggag
    15481 tgctaatcag taccgcttgt agatttttgg aagatactaa cacactaatg atttaatctc
    15541 ctttaaaaca tgaaaagaga agcctccaaa gcttctcttt tataattatc aaataatgta
    15601 caactagatt cttaataact acctaattta gtggttcaat catgaagctt aattgatagc
    15661 tatctgctga gctaagcaag aattcgtcat gaactggagc accccatgtg tcgtcaccac
    15721 ctacacccat ttgagcagca agaactttaa tccatgtagc atcagattct tgcaactcat
    15781 attggtgacg agcattttca atttgttcag tactgttacg caaagcactg aattcgaatg
    15841 ctttattaag tgcggtgaat ttaagaccat tatggttatc atcagatact gtgaattcac
    15901 gagtaccata gtgattacca gattcttgtg gcattagata tggagcaaat gtcttttcaa
    15961 cagatgtttc atatcgacca agataggcac caggaagttt atcacggtag ctttcttctg
    16021 caccgtatcc ataatagcta aggtttgtaa attgtgaacc gatagcaaat tctagaccaa
    16081 attcagggaa gtttggcaaa cctgctttac catcatagtt tgcagtaaca aagattcgac
    16141 ccttgtaatc aacttgataa gttaccttaa cttcgacatc agacaagcct ggcaattcat
    16201 gaacataagt cactttaaca gagtcgtctt cgatttgaat ttgagtatct gtaactttac
    16261 tatagtttcc agcaaccttc cagcctgcca tttcgaatgg atatccagca ccacgatcgt
    16321 tgtcagtgta agcacgagtg aagctaagtt taggaccttt ctcaatgaat tcaacaccat
    16381 tatacttagc agatactaaa gtattttgtg cacgtgaaag caagattgag aagttttgtc
    16441 cttgaatacc gatgttgaag tcgccttcaa caacattcaa aggtgcttta actggtgttt
    16501 cagtgctaat cttttcaaca acatattgac cacgaacaat ttcatgacct ttaggagccc
    16561 attcagttgc ttccctcaga acacaagcaa cttcgtaaat ttgttcagaa tttgaagcct
    16621 cgactacaaa gttaactggg aatgttgctt cttcgcctgg tttaacatca aagtgatatt
    16681 cactttcact aacttttcta ccatcttcgt aaactctagc taggaaagta taagcagaaa
    16741 gatcttcgaa gagattatca ttcttgatag ttactgattt ttcatcaaca gcaatcttaa
    16801 tattagagta aagatgttta actgtttgaa gttttggagt tagggtacga tctgcaaaga
    16861 cgataccatt tccacaaaat tcgtagtcag aaggtctatc atgccagtca ccaccatatg
    16921 ataggaattc gctaccattt ggaagtgttt tgtaaatagc ttggtcaatg aagtcccaaa
    16981 taaatccacc ttggtattct ggatatttct ctaagtcagt gtagagttgc aatccaccac
    17041 cagagttacc cattgtgtgc atgtattcac atgaaatata aggtttttga ggtttgttag
    17101 ttaggttacc tgaagcaaag tgtttatcac taacgcttga aagatcaact agtttaccag
    17161 ttgtgaggta ttcttcgata tcagctggtt tcgcatacat acgactttcg atgtctgtaa
    17221 tgtaatcaaa ctcacgacac catgcaacac cttcatagtg aactggacga gtattgtcaa
    17281 cactacggaa gtaatcagcc atgtcagcaa tatctttacc agcatatgat tcattaccac
    17341 aagacc
//
