LOCUS       c00035_JAIQWN0..       14104 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIQWN010000006.1 Streptococcus thermophilus strain CF3_14
            NODE_6_length_100669_cov_286.118552, whole genome shotgun sequence.
ACCESSION   JAIQWN010000006
VERSION     JAIQWN010000006
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:26:28
            Original ID  :: JAIQWN010000006.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14104
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14104
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[159:9104]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      160..9104
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14104
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14104
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(160..414)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.9e-14,
                     bitscore: 46.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENLNTLDLETLASVEGGGCSWGGAGGATVQGAIGGAIGG
                     AFGGNVVLPVVGSVPGYLAGGVLGGAGGTVAYGATCWWS"
     CDS             complement(665..1066)
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLTV
                     GALAFVVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFPVITFLVLSVEFYTLLTFSDTT
                     DRIVLAVLMLLLILCDFLSYLQVKKYFKQ"
     CDS             complement(1396..1563)
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIVMGLANLFRSLDAVHHTINLLGLTVLLYSL
                     LFKKWVQFQK"
     CDS             complement(2071..2301)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_4"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9e-19, bitscore:
                     60.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGVCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             complement(2657..2857)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.6e-09,
                     bitscore: 28.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKQLERFKKLDTNALSNVSGQGYGAQCVIGTTGMTIVGAAFFG
                     IAGAGAGFAGGSTAFCYDTAK"
     CDS             complement(2876..3052)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_6"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.4e-11,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGLSCDEGMLAVGGLGAVGGPWGA
                     VGGVLVGAALYCF"
     CDS             3303..4040
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="LKIYLLEDNSIQMGRLEDAVAHELMTFGKDLSCVQSFDKPDQLLS
                     AITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNNPYAIIAFVTTHIEFMPQAFGVTAY
                     KYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLSTSDI
                     KHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNLTNYEATLINGQ
                     VLPVSRMKIGKIAQIVEERGRGC"
     CDS             4034..5374
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MLTTLWLLFLTLLSAGLEIILFLYLMGQKIRLRYFFLLLIFNLAF
                     NFIYNHSSWFIIKFWGEDIYYLLLSFLLSTKTKKPLKIKIFNGLFPDILNNLSLRLITF
                     FIFPFFNISITDYKSSLLISIPSSIAPLCLSFLFIKLFKESFTILQKQKSNSPIQHIII
                     VANFFMFGYTLLLQSLMYLENTTHSSTLELRKLCIVISLVLFFIMIVFLERNIREMIQG
                     QLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNLLVTLRLGIDKDDMDIVKEVYDS
                     VLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGME
                     TLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFER
                     GVSNKGRERGIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA"
     CDS             complement(5392..5553)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_9"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.5e-08,
                     bitscore: 27.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNTINNFETLDNHALEQVVGGSGWMDYINGFLKGFGGQRTLPT
                     KDYNIPQA"
     CDS             complement(5568..6935)
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEV
                     TVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKVVKKGDTLVQYSETMEASQKEGLQK
                     QLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKTNTE
                     VNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQ
                     YATTPDASVTDQYLSQVNTNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQF
                     LQNAGQQLSSVETQINDTESKINQADVLLTNTLIQSPEDGILHLSQADKKATMAATGTE
                     LAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSA
                     TETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ"
     CDS             complement(6951..9104)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 305.5; E-value:
                     1.2e-92)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_11"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1100.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.6e-45, bitscore:
                     145.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTN
                     KEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDVPYPFIAHVNKDGKLQHYYVIYKST
                     KDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPLIFK
                     QRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMM
                     TFARDYLLTILSHRFTIDVILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALAS
                     TILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTLIVFAFMKPFERMNHDVMQSN
                     AMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQ
                     LILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRL
                     NEVYLIESEFGQSDDTYQEGIADGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVG
                     VSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHINYLPQQSYIFSGSVLE
                     NLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARAL
                     LTKSPVLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGR
                     VVETGSHQDLMSYPGFYYQLFRK"
     CDS             complement(10184..11929)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     284; E-value: 1.5e-86)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 314.5; E-value:
                     2.4e-95)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALTFLLSTTVIKSIIPLVA
                     SYFIDHYLHDMNQAASMILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGILSSFISAIFIFVTTLYTMMILDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVVIIEKTRALLSDINAKLSESIEGIHIIQAFNQEKRL
                     KKEFDAINEEHLIYASRSISLDSLFLRPAMSLLKLLAYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTAAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSSIINVLMRFYEFQSGRVLI
                     DGVDIRDYSQAELRKNIGLVLQDPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFI
                     DKLPEGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKIRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIEHGSHEELLALGGTYHKMYSLQAG
                     TMEGE"
     CDS             complement(11922..13553)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 367.6; E-value:
                     1.9e-111)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MGRVIDAITSGKLTNQILLLNLVYLLLAALGMYYLRYVWRMYILA
                     TSYRLGQIMRSRLFEHFTKMSPSFYQKYRTGDLMAHATNDINSLTRLAGGGVMSAVDAS
                     ITALVTLITMFFSISWQMTLVAVLPLPFMAFATSRLGRKTHKAFGESQAAFSELNNKVQ
                     ESVSGIKVTKSFGYQEAELQSFQETNKMTFEKNMHTMKYDSLFDPLVLLFVGSSYVLTL
                     LVGAFMIQAGQITVGNLVTFITYLDMLVWPLMAIGFLFNITQRGNVSYQRIETLLEQES
                     DVQDPAYPLPSIENGRLDFAIDRFAFEDEDTLRDIHFTLDKGQTLGLVGPTGSGKTALV
                     KLLLREHDVNQGAIYLNGHDIRDYRLSDLRSLIGYVPQDQFLFASSILDNIRFGNPDFS
                     IDKVEEATKLAQVYDDIKDMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILNPEILILD
                     DSLSAVDAKTEHAIIDNLKHTRKDKTTIITAHRLSAVVHADLILVMQDGRIIERGRHDD
                     LLAQGGWYAKTYESQQLEMEGGEAHA"
     CDS             complement(13868..14074)
                     /locus_tag="ctg35_14"
                     /transl_table=11
                     /translation="MRERGQVWSYSEVKRESQLANYNTDGRYLSETTNFELYNFVREYK
                     TSDEIRRIWNPKKDESVIHDKDN"
ORIGIN
        1 aggccgtcgc ctaatatttt attatttcat tgtccacttg acagggagct attcaatata
       61 tgttcaagat tattttttat gtttattttt attgaccttt ttgaaaaaga tattacctaa
      121 caaagcaaca acaaaaccta taataaaata taccatagat tagctccacc agcaggttgc
      181 tccataggca acagtaccac ctgcaccacc tagaacacca ccagctagat aaccaggaac
      241 tgagcctaca actggtaaaa ctacattacc tccaaacgct cctccgatag ctcctccgat
      301 agctccttga acagtcgctc cacctgcgcc tccccagcta catccaccac cttcaacact
      361 agcaagtgtt tcgaggtcaa gggtgttaag gttttcaatt gtttgagttg ccatggcaac
      421 taccccctaa aatttttatc gtgtgatctc tcaatcacat ctttagtata gcattcaagt
      481 gtctctatca gagctagcgt cccaaaaagt ggctatatgt cccgaatggt aattcctaaa
      541 gaacatcctt caatcattgg aaatcttcct ctaattttca catatttact taatcacttt
      601 cttattataa cacttttatg caaatatctt atagattgct tacagaataa tcaagcaaat
      661 gcgtttattg tttaaaatat tttttgactt gaaggtaaga tagaaaatca cagaggatta
      721 acaaaagcat taatacggct agtactatac ggtctgtggt atcactgaat gttagtaatg
      781 tgtaaaactc tacactaagc actagaaatg tgatgacagg aaagacaatg aaggactgcc
      841 gtattgttaa cagatttact gaatctggac gcttcttaag catacggtag agcagtccat
      901 taacaaaaat gactacgaaa gctagtgctc cgactgttag ccaagttcct ggcgagatct
      961 tgcttttgta gagagaaagg ctgatactta taaggaaaac tgccaacgca gcagtgatgg
     1021 ttctaaaaga tcgcaataca ctcgaactaa tattctttaa cttcatgata aaacacctaa
     1081 actatgaata acctcagtca gtcttgcaaa cctaataagc tattacattt aactctattc
     1141 ctctctgtat tttattatac agctgtaaga tttcaagtaa gcccttagcg attaaattct
     1201 actggagatg taatacagta gtgtcattag tactgatact ttaaataggc gaatatacat
     1261 atctttgttt tctctattac aaagatatgc aatcaaatat aatataatct ccgctatcat
     1321 tagcaagaat aattttactt cgggaacatc aaaaataagc atttgcaagc atcttacgtt
     1381 caaagtgacc aaaggttact tttgaaactg tacccacttt ttaaaaagta agctataaag
     1441 aagcaccgtt agccctagca agttaatggt atggtgaact gcatccaagc ttctaaatag
     1501 attagcgagg cccattacga tgagaatggt agccagtaaa tacggttttg agtttttaaa
     1561 catacttttc tccttaaagt gtttttagct agtctgtgca taatctatga attttattat
     1621 agattggaag ccgataaaaa agtagtgaca taaatgtcac tacttgtctg accttatatc
     1681 cttgataacc gtacacataa gaaagagaaa taaacataac ccgataagat ttaggcattg
     1741 aagtccaaaa ttcagttttt ctccaaagtt atgtaaggca acaaggacga agcccataga
     1801 catcattaga gacactaggc gttttttggt catgattaca aataactctt ctcttatatc
     1861 gaaattttca atcataattc acatgctatt cacagaccag caattgacaa gacatttcag
     1921 ttaggatttc ttcttaacgg aagatttctt cttaacggaa ttggtagcct tgtgtttttc
     1981 aagaaatgac ataattggct tatctaaaaa actcataaca gccatggaaa ccatccctaa
     2041 aatataactt ttcaaatcaa acataatcca tcaccaccag catgttgctc cataaccaac
     2101 accacctacg atagcacctc cagctgctcc tgcgacagca ccttgccaag tacgtgtttt
     2161 gatacctagt cgtaaaccat taccaactcc tgtagctact ccttgtttag caaaacctcc
     2221 ccagctacat acaccacctt caacactagc aagtgtttcg aggtcaaggg tgttaaagtt
     2281 ttcaattgtt tgagttgcca tggcaactac ctcctaaaat ttttatcgtg tgatctctca
     2341 atcacatctt tagtatagca tacaagtgtc tctatcagag ctagcgtccc aaaaagtggc
     2401 tatatgtccc gagtagtaaa aaaaagactg aatatcattt ttgattcagt ccatgtctta
     2461 ttgaaaaagc tttaactaat tctttctata ctgcctatag actccaaata aaaagaaaaa
     2521 gaatcctatt gatgctaaca aaagttgata gatatttcct gatgacaata gtactttgct
     2581 atataaatat atcatcgcaa tagtcgaaaa aatgattagg tatttcttca tttgtatcac
     2641 ctatctcaaa tgaagattat ttagctgtat cataacaaaa tgctgtgcta ccgcctgcaa
     2701 atccagctcc tgcacctgcg atgccaaaga aagctgcacc gacaatcgtc attccggtag
     2761 taccaataac acattgagca ccatagcctt gaccacttac attagacaat gcatttgtat
     2821 ccagtttttt aaatctttca agttgtttat tattcataaa ttcctcccat acaaattaga
     2881 aacagtataa ggctgcacct actaacaccc caccgacagc tccccacggg ccacctactg
     2941 caccaagtcc tcctactgcc agcatcccct catcacagga caacccaccc tcaacactag
     3001 caagtgtttc gaggtcgagg gtgttaaagt tttcaattgt ttgagttgcc atggcaacta
     3061 cctcctaaaa tttttatcgt gtgatctctc aatcacatct ttagtatagc attcaagtgt
     3121 ctctatcaga gctagcgtcc caaaaagtgg ctatacgtcc cgaatggtaa tttctaatgt
     3181 atccagtctc taaaattcag aaaaaaattc tcattttaca ctcataaaaa attgaaaaac
     3241 cgttttcttt atgttacaat ttttcaataa acagtattcg tcataaaaga gaggactaga
     3301 ccttgaagat ttacctatta gaagataatt ctattcagat gggtcgcttg gaagatgctg
     3361 tagcacatga acttatgacc ttcggaaaag atctatcctg tgtccagtct tttgacaaac
     3421 ctgaccagtt gttatcagct atcacttcta atacaagcga tcagattttc tttcttgata
     3481 ttgaaattaa aggtgaagat aagaagggac ttgatatcgc taaaatcata cgtcaaaata
     3541 acccttatgc tatcattgcc tttgtcacta cacatataga gttcatgcct caagcttttg
     3601 gcgttacagc ctataaatac atcaataaaa ccttagatga agctagcttt agaaaagaaa
     3661 taggggaaac cattgctcaa gtcttcccta ttaacgcaac taccacggat gagttttttc
     3721 tctacaaaac agagtctcaa ttaataaacc ttcctatgga tcaaattcta tacctatcca
     3781 catcagatat caaacaccat gttcacctcc agactatcca taccctcatg gatatccgag
     3841 caaatctggc agactttaaa aagatacaca aaaagctcta cccatgccat cggtcctata
     3901 tcgtcaatac agatatgatt atctctgtca acttgaccaa ttatgaagct accttaatta
     3961 atggtcaagt cctaccagta tcccgtatga agataggaaa gattgcacag attgttgagg
     4021 aaagaggcag aggatgttaa caacgttatg gctacttttt ctcacccttt taagtgcagg
     4081 cctagaaatt attcttttcc tttatttaat gggacagaag attcgtctga ggtatttttt
     4141 cctactcctt atttttaatt tagcctttaa ttttatttat aaccactctt cttggtttat
     4201 cattaaattc tggggtgagg atatctacta tcttctgctc tccttccttt tatccactaa
     4261 gactaaaaaa ccattaaaaa taaagatttt caatggtctc ttccctgata tcctcaacaa
     4321 ccttagttta agactgatta ctttttttat ctttcctttt tttaatatta gtatcaccga
     4381 ttataaaagc tctctattaa tatccatccc ttcatctatc gcacctcttt gtctatcatt
     4441 tctctttatt aaattattca aggagagttt taccatactt caaaagcaga aatcaaattc
     4501 tccgattcaa catattatta tagttgctaa cttttttatg tttgggtaca ccctactgtt
     4561 acagtccctc atgtatcttg aaaacactac tcactcttca actttggagc ttcgaaaact
     4621 ctgtattgtt atttcacttg tcctcttctt cattatgatt gtctttttag aaagaaacat
     4681 tcgtgaaatg attcaaggac aattggactt ccagaaaaat ctccagctag agaatctcta
     4741 cacctacaat aaacatattg aatgtctcta caattctgtt cgtagtttta gacacgatta
     4801 tagtaatctc ttagtcacat tacgattggg gatagataaa gacgatatgg atattgtcaa
     4861 agaagtctat gatagtgtgc ttcaagaatc cgataaacga ttaaatacaa gaaactttga
     4921 cttagctaga ctcgttaata ttcaggataa tactttgaaa agccttctgt ccgcaaaagt
     4981 tttacaagca gaagaagaag gtattgaagc tcagattagc atcccagaac ccatccactt
     5041 gattgggatg gagactctgg acttcattat cgtcacttct atttttttag ataacgctat
     5101 tgaaggtgcc attcaaactc aaaaccctaa aattactatt agcttttggg aagatcattg
     5161 ttcacagcta ttatctatta gcaataccat aagtgaagaa aaaacagaaa ccaaaaccat
     5221 atttgaaaga ggtgtctcca acaagggacg agagcgaggc attggccttg ctaatgtcac
     5281 agaaatctta gataactata tcaatgtaaa cttagaaaca cagagtaaca atttctcatt
     5341 cacacaacaa ttaacaataa ctaaaaaggc ctaacagcct tttttctata cctaagcttg
     5401 aggaatgtta tagtcttttg ttggaagcgt tctttgccct ccgaatcctt ttaggaaacc
     5461 atttatataa tccatccacc cacttccacc tacgacttgt tcaagagcgt ggttatcaag
     5521 tgtttcaaag ttattaatcg tattgttagc catcagtaat tctcctccta ttggtcttgc
     5581 aagtttagta acttgtcttt aaagtaattg aagtaggtct tttggtcaat aacgcttgtc
     5641 acacgacctt ctagaccgta acgtagattt tgggcttctt tttctgaaat acttgcccta
     5701 gcagttactc taaacacatt ccccctttct gtttccgtgg cagaattatc aatactctca
     5761 agttttccaa taattgtggt accgtgatta ccaaccttat ccaaggtcag tcgaactgac
     5821 tggccttttt gcagttttgg cacataatcc gaattcacat aataagtaat ggcaacttcc
     5881 tgggtttgag tcatatcggg ataaagctgg gccaactcag ttcctgtcgc agccatggtt
     5941 gcttttttat cagcttgact caagtgtaag attccatctt ctggtgactg gatgagggta
     6001 ttagtcagaa ggacatctgc ctgattgatt ttactctcgg tatcgttaat ttgtgtttcc
     6061 actgagctca attgctgtcc tgcattttgc aagaattgat tttttagagc ttctttttta
     6121 gtgctatcac tattgtcata agttacaact gtgcctgtcc cagccttttg gatttctaga
     6181 ttacctatgg aagcattcaa gctcgaaata ttggtattaa cttgagatag gtattggtct
     6241 gttacactgg catccggtgt cgtagcatac tgactgttat aggcatttaa ggttgcctga
     6301 tgaggattgc cttcaggtaa agtcgtttca tgattggtaa tagcttgaga gagcgcctca
     6361 tactctgaga cctgagtctg caattgacta atctggttat caatagcaga accggtatta
     6421 ctcgcaattg ctgcttggtt attaacctct gtatttgttt tagccacacc caagtcaata
     6481 tcctgtgcct gacttaggta ggtgttaaaa gtactctgat aaccaaactc gtcttcctgt
     6541 tcttggaaaa gattggttcc ctgcgttagg ctagattgca aggtcttcaa acctgattcc
     6601 tgtcttttta aaagttctag ttgcttttga agcccctctt tttgcgatgc ctccatggtc
     6661 tctgaatact gaactaaggt gtcccctttt ttaacaacct tattagcaac cagttgatta
     6721 tctatgatgg tattgtcact ggttgattgg attactgcga taaccttggt tggctctata
     6781 cttcctctag acgtgactgt aacttccttc ttagcaaaaa aagcgaaaag aaaaaggaaa
     6841 ataactaaca aaatcaaggg agtaatcaaa acagtagaca tattgtggta gcgacgatgg
     6901 taaaactctg tgcttttaaa caactgtgga ttcatcgtgt ttccttttcc tcactttcta
     6961 aataattgat aatagaaacc tggataagac attaggtctt gatgagaacc tgtctccact
     7021 acgcgtccgt gatcaatgac tacgatacgg tcggtccgct cagcgatact aagcctgtgt
     7081 gctacaaaga tgatcgtttt atcttttagt gctaggaggt tatcaataac ctgcttttct
     7141 gtcaaaacat ccaatccgct agttgcttca tctaagatta gtacaggaga tttcgttagt
     7201 agtgcacgcg ccaaagcgat acgttgcttt tgccctccag acagacctgc tccatcagac
     7261 agctctgtct gaaaccccat aggcatgttt tcaatatctt gacgaatttc tgctatttca
     7321 caagctttca aaatatcagc ttgcgtaata ccccgtgctg cacctaaagt aagattttct
     7381 aaaacactac cactaaatat ataggattgc tgagggagat agttaatatg ttgacgaaga
     7441 gttttcttgt ctatgcgact aatattttga ccattaaaat ctatgtgccc cttatatggt
     7501 tgataaaaat tgaccaacat tttagctaga gtagtcttac cagatccact gacaccaaca
     7561 aaactgattt tttctccttg tctaatcgtc aaactgacat cagtcaaagt atcacgacca
     7621 aaaccatatt tataagataa atccgtaaca gtgatatctc catccgcaat gccttcttga
     7681 taggtatcat cactttgtcc aaactctgat tcaatcagat agacctcatt gagcctagta
     7741 ttagctacct tagcagactg taacttggtt tgcaggttaa tgatattttc caaaggattc
     7801 gtgaagtaag aaagcaacat attaaaagta atcaattgtc ctatcgaaat ggtatttccc
     7861 atcaccaact gagcacctgt ccagaggata agtacattta aaataagttg agcaccttgt
     7921 ttcaatgatg tttgtagtat ggataactta gaaaggcgaa aagaattgtc tagatagtca
     7981 ataaactcac catcaatctt ttgatagcat acttcttcgc tggttagtga ctttatggtt
     8041 tcaatcccat taatgtcctc aatgatggct gaattaacca tagcattact ctgcatgacg
     8101 tcatgattca ttcgctcaaa aggtttcata aaggcaaaga cgataagggt ataaattgga
     8161 accgaacaaa gaactagctt gaagagattg ctattttgta tcaataacac gcctcctacg
     8221 ataatcacaa tagagaaatc aaggaaaagt gataatatcg tcgaagccag agcatcgata
     8281 atagagttag catcactaaa acgtgagata acctcccctg tacgtcttgt ggcaaaaaaa
     8341 gacattggga gttcaaagat atgtcgtatg taggacaaga taacgtcaat ggtaaatcga
     8401 tgactcagta tggttaagag ataatctctt gcaaaagtca tcatttgttg taaaacatag
     8461 gtcacaacta atccaattga gataattcct aaggtagact tcatttgatt agggacatat
     8521 tcgtctagaa taccttgtaa ataataggaa cctaaaatat ttattaaagt aaccaagaga
     8581 ctggcaaaga caatattagc tatcaaggac ctttgtttaa agatcaaagg gagaaagtcc
     8641 cagagtccat ttttcttatc cttatgtggt ttataactgg gttccggtcc cataaaaaga
     8701 gtaacacctg tccactcttt ctcaaaacgc tctttagtca ttttagttac ttttacactt
     8761 ggatcagggt ctccaattat cagataatcc ttggtgcttt tataaataac ataataatgt
     8821 tgaagcttcc catctttatt aacatgagca ataaaaggat aaggaacatc ttccatctca
     8881 aagagcgaca tttcagcctt tatagctctc gtttcaaagc caattttttt agcagcctct
     8941 acaagaccta aggcagttgt cccttcttta ttggtcttcg ccaactcacg cagatgtgct
     9001 aatgaataat ctgaaccata gtacttggcc actgatgcca aggcagcaac tccacaatcc
     9061 ctcatgtcta tttgagggac aaaagtccta cgaaaacgaa acataccaaa cctaaatcaa
     9121 gtagaagaaa aacttggcta caggacaaaa gtcctacgaa aacgaaacat accaaaccct
     9181 ttcatcacaa attatcatat gattagtatg tcatattttc aggataaaaa gagccagcgt
     9241 cccaaaaagt tgccatacgt cccaaacggt aagaaaaatc ttaaagtcat ctccactatt
     9301 accatttaag ccgtatttgg ggtcatttag gacaagttca ttgaaatcga tttcaaagtt
     9361 atacaatagt tattagaagg aaacattcta aaatagtcct acaagcatac gtatttgatc
     9421 taaccattat tactgtgcca gccctggtat ttccaaagga aaccatgact gctgatagcc
     9481 tcggagccta tctctatcgt atgatgtcat aatttgatta tttttattcc gaaaagggat
     9541 aacattatga aaaacgtcaa tccatatctc aaaaaatcct atcaaaaaag gctaaatcag
     9601 cctcttgaga ttcgattact caattatcgg tttaattttc cttagctttg taagtgtatt
     9661 tgttatcact gtcaatgcta tttttagcgt cactagaggg gttcccttcc ttaatgccca
     9721 ccttatttcc accttgagta attgtgcctt ctatcttttg atttactcaa ccttgaggtg
     9781 gcaccatctc aaaaagctct ataatctcta cagtggtttt tcccactaca gaaattatag
     9841 agccgaagtt aagtagttct gtggtaaact gagtcatagg aataaatctc tttctagtaa
     9901 tgttttgcaa ctctactata acggatttat tcctttttgt gtttacacaa cttattttac
     9961 actacctcaa cgtttgcaag tacctcgaga tcgagtgttt caaatgtatt atttgtttgc
    10021 cttgtcattc taacaacctc ctaaattatt tttagctttt tctctcaagc tatgatttta
    10081 ttatagggtg gtagccaaca aaaaagtagt gacataaatg tcgctactcg attttgattt
    10141 ttaagaaatc ttttcgaata tagaagctat ggtctagatt agcttactct ccttccatgg
    10201 tgcctgcttg taggctgtac atcttgtgat aggtgccgcc gagggctagg agctcttcgt
    10261 ggctaccgtg ttcaatgatg cggcccttgt ctaagacata gatgcagtta gcatcttgga
    10321 ttgttgatag gcggtgggca atggcaatgg ttgtacggcc ttgacgaatt tttgcaagag
    10381 agttttgaac aatagcctct gtctccgaat caatattggc tgtcgcttca tccaaaatca
    10441 agattttagg ctggctagca acggttctag caaaggctag aagctggcgt tgaccggttg
    10501 agaaacttga accacgttcg gaaactgggg aatcatagcc ttcaggaagt ttatcaataa
    10561 agtgattggc atcgacaaac tcagcagcag ctttaatctc ttcatcagtt aaatcttgat
    10621 acatggcaat attggatttg attgtgccat gatagaggaa ggggtcctga aggacaagac
    10681 caatattctt gcgcagctct gcctgactat aatcacgaat atccacaccg tctatgagaa
    10741 ctcgtcctga ttggaattca tagaatcgca tgagcacgtt gataatagag gattttccag
    10801 agcctgtaga tcccacaaag gcgatggttt cacctttatt gacagagaag gaaatattat
    10861 ccaaaatctg gtgcttgcca tcataggaga aggagacatt ctcaaagcga atattcccct
    10921 cagtaacctt ggcagctgtg tctctctgtt caggctcata ggtacgctcg tcaatcaagg
    10981 caaagacccg acctgctgag accatagagg tttgtagagt cgagaagttt tgtgtcactt
    11041 caatcaaggg atcaaagagg cgattaatat actggataaa ggcatacatg gtacctgctg
    11101 tgatacccag atagatacct cggtagccaa aataggccat gagaacagca taagccagga
    11161 gcttcagtag actcatggct gggcgtagaa agagagaatc cagtgatata gaacggctgg
    11221 cataaatcag gtgttcctca ttaatggcat caaactcttt tttaagacgc ttctcctggt
    11281 taaaggcctg aatgatgtga atcccttcga tactctctga cagtttggca tttatatctg
    11341 aaagcaaggc tctggtcttt tcaatgatga ccactgattt tttgcgataa aggttaacca
    11401 aaaggacaat cagaggaaga aagaggacaa taagcccggt cagacgaatg tccaagatca
    11461 tcatggtgta aagggtggta acaaagataa agatagccga aataaaacta gacagaattc
    11521 ctgagaacat ctcgctaatg gtctcagtat cattggtcaa gcgggaaacg atggaacctg
    11581 ctggggtctt gtcaaagtaa gacataccca gtttttccat attggcaaag gcatctcgac
    11641 gaatatctct gacaatgcta taggacacac gcgcaaagaa gagatttccc agatactgga
    11701 ctagtgtctg caagaggtag agaccatagt agccaatcag aatcatactt gccgcctgat
    11761 tcatatcatg aagatagtga tcaataaaat aagaggccac caagggaatg atactcttga
    11821 taaccgttgt ggacaagagg aaggtcaaag ctagaaaggt caagaacttg taaggcttga
    11881 gataggtcaa gagacgctta aacacagacc attggttttg attaggcatg agcttctcct
    11941 ccttccattt ctaactgttg agactcatag gtcttggcat accaaccacc ttgagctagt
    12001 aagtcgtcat gacgcccacg ttcaatgata cgaccatctt gcatgaccag gatgaggtca
    12061 gcgtgcacca ccgcactgag acggtgggcg gtaataatag ttgttttgtc cttgcgagta
    12121 tgcttaagat tatcaataat ggcatgttct gtcttagcat caaccgcaga taaggagtca
    12181 tccaaaatca aaatttctgg attcaaaatc atggcccggc tcatagccag acgttgtttt
    12241 tgaccacctg ataggctgac acccttttca ccaatgattg tttcaaagcc ttcaggcata
    12301 tccttgatat catcataaac ttgagctaac ttagtcgctt cttccacctt atcaatggag
    12361 aaatctggat taccaaagcg gatattgtct aaaatagaac tggcaaagag aaactggtct
    12421 tgaggaacat aaccaatcaa gctacgcaag tctgataggc gatagtctcg gatgtcatgt
    12481 ccattcaaat agatggctcc ttgattgaca tcgtgctccc gcaagagcaa cttgacaaga
    12541 gccgtctttc ctgagccagt cggtccaacc aaaccaaggg tttgcccctt gtccaaggtg
    12601 aaatgaatat ctcgcaaagt atcctcatcc tcaaaagcaa agcggtcaat cgcaaagtct
    12661 aaacgaccat tttcaatgct tggaagagga taagcgggat cttgaacatc tgattcctgc
    12721 tctaaaagag tctcgatacg ttggtaggac acatttcccc tctgcgtgat attaaagagg
    12781 aagccaatgg ccattagggg ccaaaccagc atgtccaaat aggtaataaa ggttaccaaa
    12841 tttccgaccg ttatctgacc ggcctgaatc ataaaggccc cgacaaggag ggtcaaaaca
    12901 taagatgagc caacaaagag caaaaccaag ggatcaaaaa ggctgtcata cttcatggta
    12961 tgcatattct tttcaaaagt catcttattg gtctcttgga aggactggag ctcagcctcc
    13021 tgatagccaa aagacttggt taccttgata cctgacaccg attcttgtac cttattatta
    13081 agttcagaaa aagctgcctg ggattctcca aaagctttgt gggtcttacg tcccaaacga
    13141 ctagtcgcaa aagccatgaa aggtagaggt aagactgcca ccagggtcat ctgccaggaa
    13201 atgctgaaga acatggtgat taaagtcacc aaggctgtga tagacgcatc cacggctgac
    13261 atgacacccc caccagccaa acgggttaga gagttgatat cattggtggc atgggccatg
    13321 agatcaccag ttcggtactt ttggtaaaaa gaaggcgaca tcttggtaaa atgctcaaaa
    13381 agccgcgaac gcataatctg tcccaagcga taagacgttg ccaagatata catccgccaa
    13441 acatagcgca aatagtacat tcctaaagcc gccaaaagca aataaacgag attcaaaagc
    13501 aagatctgat tggtcaattt tcccgatgtg atagcatcaa tgacccgacc cataaccata
    13561 ggaggaatca gattgagaac cgaaaccaaa ctcagtgcca atatcccgac aatataacgg
    13621 cgtttttcta acttgaaaaa ccaccaaagt tttgcaatga ttgattcttt aaaaaaacaa
    13681 gttattcccc ctatccctac aaaaggatga ttataagtct aatgaaagtt atttccaata
    13741 gcgataaatt gtaccatctt ctaactgaaa gtgaccaata taagtcaatt ttccaaaatc
    13801 agtagactct ggcaattgat aagcaaagga gtcaaaatta tagaccttgt gcccatcatc
    13861 aatagaatca gttatcctta tcgtggataa ctgattcgtc cttcttaggg ttccaaatac
    13921 gtctgatttc atcagatgtc ttatactctc tgacaaaatt gtacaattcg aagttagttg
    13981 tctcactgag atagcgacca tcagtgttgt agttagctaa ttgagactct ctcttaacct
    14041 cagaatagct ccaaacctgc cctctttctc gcataatatc ggcatcacgg ccacttttga
    14101 taag
//
