LOCUS       c00012_JAIQWN0..       15267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIQWN010000020.1 Streptococcus thermophilus strain CF3_14
            NODE_21_length_24808_cov_213.185755, whole genome shotgun sequence.
ACCESSION   JAIQWN010000020
VERSION     JAIQWN010000020
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:26:28
            Original ID  :: JAIQWN010000020.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15267
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15267
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1213:5267]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1214..5267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..15267
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15267
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     CDS             complement(101..274)
                     /locus_tag="ctg12_1"
                     /transl_table=11
                     /translation="MNSVRRRHPELSPASPHKLRHTGATLARKSGVPLEIISEALTHSD
                     KQITKTYVNTKI"
     CDS             418..681
                     /locus_tag="ctg12_2"
                     /transl_table=11
                     /translation="LAHDFASWVSGDSMEPKYHNGSVALIRETGFDYDGAVYAVVCNSQ
                     TYIKRVYLEAEGLRLKYKDIFISYDEDPRVVRIIIGNFIPLK"
     CDS             931..1035
                     /locus_tag="ctg12_3"
                     /transl_table=11
                     /translation="MENTEFSLELDVTEVSTEQGYVSGGVTSTGCCKD"
     CDS             1214..1492
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_4"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6e-15, bitscore:
                     45.2, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVANPQFFHNLTKEKIYKNSTFRNYVKRSITRATPFGLFSSIG
                     VGTFSDISYHQKIGENYTKKISVSGEWLSSICMMLENKDSVLLQLHI"
     CDS             1643..4006
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     577; E-value: 1.1e-174)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_5"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.5e-65, bitscore:
                     210.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.6e-19, bitscore:
                     59.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLELVLQSKSPDLEKQKILDYIRNLITNEFLFTNLRKVAISHKDL
                     DDLTNILKDINNQRKLTEDLLQIKNSIEQYAKLELGEGISQYTEICKKMSYIFNDKKQH
                     YLKVDLVNCCDSVLPKNLKKKMEDFVNFISKINLAKGYRNRELESFTEKFVEKYGEYVE
                     VPIKELLDGNLGLGLPKQTLGTHVKSSSSVEEQNFLSYLSKEVFKAVKNCKKEIDISNI
                     PLGLLYPNSDRFVANQLELYCEIKNFESQPVISVVPNTGSDMIGKSIGRFASYFPNSYI
                     SLDSQLDNVELIEFPRDSKNLNVMSAQNAHSKKLLLSYDDNDNTSIELDSVVVGVIKTE
                     YRYKLYFRDLRTGSIVNFVTTSMLNHKSNGVFSDLARFLLAVSLEWQDNPFSVFRIIEN
                     FDYLPYIPKIKYGNIILSEEKWVLSDIDKNDLSSIKQWKKDFDVPRLLYFHKADERLLV
                     DLENDLDTQWLLKQNVDKLYFTRFEKYDGKNCEFIFGFENYQSSINHYSMQEKSVRRLT
                     NNFYKNYVKTFSSDWIYFRLYGINSSILLELRERLLLFTDELLVEKLISDFHFVNYSDK
                     DNGSLRLRFKINNDDNFEDLRFRIAHWIDFLLESGFCNDVSFNLYEREIERYGGDNFIT
                     VCERMFSIDSFLTLKLFSKKLLNDKDLFSVLHSTFLYIRLLGIPLKRLLELLKGNLTQN
                     RYRKSFKKLFPNNTIVVKEFKEYFDYKNQFEIFNEVFREFPPIDGYFEGKNDIVYSLLH
                     MHMNRVGMFPYREKEYLYFIMYIAEPLNNYKEFT"
     CDS             4044..5267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     308.8; E-value: 9.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_6"
                     /sec_met_domain="LANC_like (E-value: 3e-52, bitscore:
                     168.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLDSDIIDRLQRAYYTENRSYLSEYPSIIIYLSYRLINCDNKEYS
                     KLLYNRVNYYLQELLKSIKLNSTNNISLCYGFTGYVYALEFLSKNCKGYDKLLDTLETI
                     LLALTKDRLREIKSSNIVKEEYFDVIQGVSSVARYLLSKEESTSEQELLVKEILNYFAD
                     LIINEPTIYVEYMPNEKLRKRFPSGYINLGVAHGILGPLYVLALGFEKFNITKHIPSIE
                     KGLSYYENAFFTNTIGKIIGWNGRVSDYEENEEFRFNISWCYGSLGMARVLYNIAKIID
                     SQKLREMAMDVFTSSIDYLNSSEILNNGICHGRSGIMLLFNLMYLDTGKTQFKAISDNL
                     FKEIINDASNSEYIFVERDIYFRGVTFDEVIDYIDFGLLNGVSGIVITLMAQRTGNAYP
                     LDRMLFMQ"
     CDS             5291..6556
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 93.6; E-value: 2e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg12_7"
                     /transl_table=11
                     /translation="MRKILKNKLYLKVLVSDLISNFGDTLYFIALMTYVTEIKESNLAI
                     SIVNISETLPILFTIFFGIIADKTLNKVKMIIKTLWLRVILYLLVAVAMNFKPSIIVVI
                     IASLVNLVADTLGQFENGLFYPISNRIVKKSDREETMAFRQTVVSTMNIVNQSLGAFLI
                     TFFSFSHLAFINSLTFAISLLIMLAIRNQINSYYDETISTSKISQFDFKASFSEIISNL
                     KLSINHLFSIGNMKEALLVIPILNGSLAILIPLVVVNLSKDSNLTIVNSAITISLLGIS
                     TVSGGILGGTLILISKKFKSLSIGTLLKMNLTIVLLSFVAFYFQNIYLIILSSFLSSVL
                     VSALNPKMGTIIFNNIDETKLATIFGGMVTYFQIGDIVSRLLFSTLVIYLPYGYIALIY
                     IAVVFVAILYTLKSSNHIEREF"
     CDS             6566..6733
                     /locus_tag="ctg12_8"
                     /transl_table=11
                     /translation="MIIVFQIFYYENLFSRLSTKVRDFVRTQLREFQYLDDGQFKTLPE
                     YPEFAWFEGM"
     CDS             6784..7296
                     /locus_tag="ctg12_9"
                     /transl_table=11
                     /translation="MMFDDRLEIYSPGKLPNIVTVENIKHERFSRNPRIARTLTEFGWV
                     REMNEGVKRIYSEMESYFLHEPKYTEPGNKVVLTLENNILSRHLRVNDKMMKKYDEFND
                     LNDDEKAILHIMYNTGEKMTTALAARITNRGRNFASKLLKSLVNKEILEWHGTSKQDRN
                     QYYTLAE"
     CDS             complement(7633..8850)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 110.6; E-value: 2.2e-33)"
                     /gene_kind="other"
                     /locus_tag="ctg12_10"
                     /transl_table=11
                     /translation="MSIKKTKNGTYQLRLYIPEDVQAKLGLGKLFERKYKTRREAKEVE
                     LKLSIDIKNAKSGKSHINIKNKGEIIFKKFYEDIWLEPYKAGQTTTTIKPPTKATVFQT
                     ENIFRLHILPILGKYSIEYPNNNKQLILSLLTPKANSYANFKVIRSYVNSVFDWAEELE
                     YIPSNKLRKTITRIKANKKILLKESKREEDLSLDKEELKLWLQAFDIDLEKGLIDLKDY
                     TLFYTTFFLSDRKSESYALQWKHINFSTGETLIEQALDRFGNIKPTKGRKKTLFKTPIE
                     LIELLANWKARQQEELKLFGLRQTQKQFVFTYNDRSNNINLPLHVDYLNYRMKSVRRRH
                     PELAPASPHKLRHAGVTLAKQAGYSLEAISEALTHSDKQITKTYVNTKDIVNRTVGDIA
                     FRSLKK"
     CDS             complement(8861..9133)
                     /locus_tag="ctg12_11"
                     /transl_table=11
                     /translation="MLVQLPEEQTQEIQQMIATLIKNEIHHFKEDIGADSTFLNKKQTY
                     NYLGISNNTLDIGIAMGLPYIRIGKSISFNKKSINQWMTRLEISA"
     CDS             complement(9195..10385)
                     /locus_tag="ctg12_12"
                     /transl_table=11
                     /translation="MIKESFPFDILNLFDTKGTPPFNFSNQYLNPNTKILDFNNATLYE
                     VDFDSLSPDTKAKLQEGAYKIGESRKVEGNLRAVIVDTTDQKNRVEDLTLRKMTNNNEN
                     QVPSDLIAQAQLKQIYNLLLDIKESQDYQIRWERNNSILAPFYSARTKVIEANNSKDFR
                     EKVKSLKDANTLFEESVSAIKSDIISNRDEIIKKISQPTYRQASLQTHADFLLQDIEIM
                     TKIVGMQIYIDLTLNNEGIAHDRLLSFQGSMELVSKQNIPYKTNYLKELAKKLLYVKEL
                     KWIKNNSIPKVSLLELIHNHYSYSKNNRDLFININTKLIEFHQDSNVNLSNTETAKIET
                     EKKMTLKTKKCKTCKKTISSPKTIPICDACRNKGKQLTVVGVALLVFFNKIINKKN"
     CDS             complement(10632..10889)
                     /locus_tag="ctg12_13"
                     /transl_table=11
                     /translation="MGNGGQWMNAPGYQTTHTPTEHSALSFSPGQAGADPTYGHIAFVE
                     QVKSDGSILISESNIKGLGVVSYRTFDAETAKQITYVIGH"
     CDS             complement(10865..11230)
                     /locus_tag="ctg12_14"
                     /transl_table=11
                     /translation="MTKRKNLRVVLSTRQQMVASTSPIPLALGKGVLKPCKNSIPISMS
                     MEVHQKPLNRRKEKPETEAVSQQGMSHKAIASPKKSIPQATQDCLILGDNVPGLSITEE
                     KKSVLASESIWEMVANG"
     CDS             complement(11397..11585)
                     /locus_tag="ctg12_15"
                     /transl_table=11
                     /translation="LIEQDHRPVKRHNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTL
                     FGFSVCTEIKVLLGIPA"
     CDS             complement(11591..12085)
                     /locus_tag="ctg12_16"
                     /transl_table=11
                     /translation="MTINHFKGKQFQQDVIIVTVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDEIYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQTAYAFLERLVKQFDEPKVVVTDKAPSITSAFKKLREYGAFIKGQNIVPLN
                     T"
     CDS             12235..13452
                     /locus_tag="ctg12_17"
                     /transl_table=11
                     /translation="MKQSQAKKHDNTMTNKILMRLIALVLGLLFLEILIIHSKNEQQKS
                     VSNQVQTARIMANGDLLYHDGLYMSALQADGSYDFTENFTYVKPWLKQADLVLGDFEGT
                     INPDYPLSGYPLFNAPQSVTAAISDAGYDVMDLAHNHILDSGLEGAFTTADAFKEVGID
                     PVGVYENPVRDKAPLFIKNVNGIKVAILSYAYGFNGLESNLTEKEIANHLSNLDEKRMK
                     VEIERAEKEADVTVIMPQMGVEYRLEPTDEQVKLYHKMIDWGADIIFGGHPHVVEPSEV
                     VKKDGQQKLIIYSMGNFISNQRIETMDGVDSAAWTERGVLMDVTLEKKNCQTTIKTAQA
                     HPTWVNRTPKGTISPEGYPLYTYQTYILEDFIKGGKYRNKLDEETKERIDTAYKEMNAH
                     VNLKWK"
     CDS             13773..14039
                     /locus_tag="ctg12_18"
                     /transl_table=11
                     /translation="MKAIITVVGKDKAGIVAGVATKIAELGLNIDDITQTILDEFFTMM
                     AVVSSEDKKDFTHLRAELEAFGESLNVKINIQSSAIFDAMHNL"
ORIGIN
        1 aaaaaggctc cataatctcc atagaggatt tacccactac agaaattata gagccatttt
       61 tttaagcttc tatatgcaat atctccagca gtttgattta ctatattttt gtgttaacat
      121 aggtctttgt aatttgttta tcactatgag ttaatgcctc ggaaataatt tctaggggaa
      181 cgccagattt tcttgcaaga gtggcacctg tgtgtcttaa cttatgtggt gaagcagggg
      241 atagttctgg atgcctacgt ctgacagaat tcattctata gttgaggtaa tctgtatgaa
      301 gtggaaggtt gatattattg gatcggtcat tataggtaaa cacaaactgc ttttgagtct
      361 ggtgtaaacc aaatagtttt aattccttat tatgaaacgg tttactttac ggaggagttg
      421 gcgcatgact ttgcctcatg ggtgtctgga gattctatgg agccaaagta tcacaatggt
      481 tcagttgctc tcattcgtga aacaggtttt gactatgatg gtgccgtata tgctgtggta
      541 tgtaatagtc aaacatacat taagcgagta tatcttgaag cagagggtct acgtctaaag
      601 tataaggata tctttatttc ttatgacgag gatccacgag tagtgagaat tattattgga
      661 aattttatac ctctcaaata atacgttttt ctagtcctga attgtcaact tgtttgcttt
      721 tttgataatg attctagttt tcaaaaatgt aatgacatct gttaaggatt tcttatgaaa
      781 tatcttctga taacagagct tgtttgatag tacagacgga ttttatttta taatactccg
      841 aaacaaaaag aatgaatttt ctaaaaatta ttgacaaata aatttgcttt tagtattata
      901 aacacaactt aaagaagagg cagagttatc atggaaaata ctgaattttc attggaactt
      961 gatgtaactg aagtttcaac agaacaaggt tatgtttctg gtggtgtaac atctacaggt
     1021 tgttgtaaag attagtttta taattgattg aataaggcag gtatacgagg tacttacctt
     1081 tttttacaag agaattatgt ttaagataaa agataattac atttataggt aatgcgttaa
     1141 tgattcaaga cttatagaaa aacttagtga aaataatctt gaaatatttt ttgataacaa
     1201 agtttttaaa gaaatgttgc tagtggcgaa ccctcaattt ttccataatt taactaaaga
     1261 aaaaatatat aaaaattcca cctttagaaa ctatgtaaaa agatcaatta caagagcaac
     1321 gccgtttgga ttgtttagtt caattggtgt aggaactttt tctgatatct catatcatca
     1381 aaagattgga gaaaattata cgaaaaaaat ctcggttagt ggagagtggc taagttcgat
     1441 ttgtatgatg ttagaaaata aagattctgt cttattacaa ctacatatat agtggaacca
     1501 aaaagtactt gaattatcag ataagtatca attaagtaat gtcaattact ggggaatctc
     1561 tgagataagt aaggatttat ttatcaagaa aactggactt ttagaattca tacaaaaatt
     1621 aacgtataaa tcggaagtca gtgtgttaga actggtactt caaagtaaat ctcctgattt
     1681 agagaagcag aaaattttag attatatacg taatttgatt actaatgaat ttttgtttac
     1741 aaacttgcga aaagttgcaa taagccataa agatttagat gatttaacca acattttaaa
     1801 ggatattaat aaccaaagaa aattaaccga ggatttatta caaataaaaa atagtattga
     1861 gcagtatgca aaattagagt tgggagaagg catttctcaa tatactgaaa tttgtaaaaa
     1921 aatgtcgtat atttttaatg ataaaaaaca gcattacctg aaggtggatt tagtaaattg
     1981 ttgtgattcg gtgctgccca aaaatttaaa aaagaaaatg gaggattttg ttaattttat
     2041 ttcaaaaatt aatctggcta aaggttatcg aaacagagaa ttagaatcat ttacagaaaa
     2101 atttgttgaa aaatatggag aatacgtaga agttccaatt aaagaattat tagatggtaa
     2161 tttaggactg ggtttaccaa aacaaacttt gggaactcat gtaaagtcat caagtagtgt
     2221 agaagagcaa aattttttgt cttatctgag taaagaagtc ttcaaagctg ttaaaaattg
     2281 taaaaaagag atagatatat caaatatacc tttaggattg ttatacccaa attcggatag
     2341 atttgttgca aatcagttag agttatattg tgaaattaag aattttgaat ctcaacctgt
     2401 tatatcagtt gtcccaaata cagggagtga catgataggg aagtctattg gaaggtttgc
     2461 ctcctatttt cctaattctt atatctcgtt agattcacag ttggataatg tagaattaat
     2521 agaatttcca agagatagta agaatttaaa tgttatgtcg gcacagaatg ctcattctaa
     2581 aaagttatta ttatcttatg atgacaatga taacacatcg attgaattag attctgtggt
     2641 ggtgggggtt ataaaaacag aatatcgata taaattatat tttagggatt tacgaaccgg
     2701 ctcaattgtt aattttgtaa caacatcaat gctaaatcat aaatcaaatg gagtatttag
     2761 cgatttagca agatttttgc tagcggtttc tttagaatgg caagataatc cgttttcagt
     2821 gtttaggata attgaaaatt ttgattatct tccctatatt cccaaaatta aatatggaaa
     2881 tataatttta agtgaagaga agtgggtttt gtcagatata gataaaaatg atttatcttc
     2941 tattaaacag tggaaaaaag attttgatgt acctagacta ctgtattttc ataaagctga
     3001 tgagcgtcta ttggtcgatt tagagaatga tttagataca cagtggcttt taaaacaaaa
     3061 tgtggataaa ctgtatttta cacgttttga aaaatatgat ggtaaaaatt gtgagtttat
     3121 ctttggattt gaaaattatc aaagtagtat aaatcattat tctatgcagg aaaaatctgt
     3181 tagaagattg acaaataact tttataagaa ctatgttaaa acattttcga gtgattggat
     3241 ctattttaga ttatatggaa ttaattcatc aattctactt gaactaagag agcggcttct
     3301 tttgtttaca gacgagctat tggttgaaaa gctaattagt gattttcatt ttgtaaatta
     3361 tagcgataag gataatggat cgcttcgatt acgatttaaa ataaataacg atgataattt
     3421 tgaagattta agatttcgaa ttgcacattg gatagacttc ctactagaaa gtggtttttg
     3481 taatgatgtt agttttaatt tatatgagag ggaaattgag agatatggtg gagataactt
     3541 tataacagtt tgtgagagga tgttttctat tgacagtttt cttaccctaa agttattttc
     3601 gaagaaatta ttaaatgata aagatttatt ttctgttttg cattcgacat ttttatatat
     3661 tcgattatta gggatcccat taaagcgatt acttgagttg ctgaagggga atttgactca
     3721 aaatagatat cgtaaaagtt ttaaaaagtt attcccaaat aacacaatag tagtaaagga
     3781 attcaaagaa tattttgatt acaaaaatca gtttgaaatt tttaatgaag tatttagaga
     3841 gttcccgcct attgatggat attttgaagg taaaaatgat atagtctata gtttacttca
     3901 tatgcatatg aatagagtag gcatgtttcc atatagagaa aaggaatatc tttattttat
     3961 catgtatatt gcagagccgt tgaataatta taaggaattt acttaaaaag tatgaagaaa
     4021 ttatctgtaa agtagataaa ctcgtgttgg atagtgatat tattgacaga ttgcagagag
     4081 catattatac agaaaataga agttacttat cagaatatcc aagtataatt atatatttat
     4141 cctataggtt gataaattgt gataataagg agtattctaa gcttctctat aatagagtaa
     4201 attattatct acaagaattg ctaaagtcta ttaaattgaa tagcactaat aatatttcac
     4261 tttgctatgg atttacgggc tatgtatatg ccttggaatt tttatctaaa aattgtaaag
     4321 gatatgataa attactagat acacttgaga caattttatt agctttaaca aaagataggc
     4381 tacgtgaaat aaaaagctct aatattgtta aagaagaata ctttgatgta attcaaggtg
     4441 tctctagtgt agctagatat ttgcttagca aagaggaatc aacttctgaa caagagttat
     4501 tagtaaaaga aatattaaat tactttgcag acctaataat taacgagcca actatttatg
     4561 tggaatatat gccaaatgaa aaattaagga aaagatttcc tagtggctat attaatctag
     4621 gtgtagctca cggtatattg ggaccactat acgtgttggc gttaggattt gaaaaattta
     4681 atataacaaa acacatacct tcaatagaaa agggcttgag ttactatgag aacgcctttt
     4741 ttaccaatac aattggaaaa ataattggtt ggaatggtag agtcagtgat tatgaggaga
     4801 atgaggaatt tagatttaat ataagttggt gctatggcag tcttggaatg gcaagagtac
     4861 tatataatat agcgaaaatc attgatagtc agaaattacg agaaatggcg atggatgtat
     4921 ttacttcatc tattgattac cttaatagca gtgagatttt aaataatgga atttgtcatg
     4981 gacggtctgg aataatgctt ttgttcaatt tgatgtattt agatacagga aagacacaat
     5041 ttaaagcaat ttctgataat ttatttaaag aaattataaa tgatgcttct aattctgagt
     5101 atatatttgt ggagcgtgac atatatttta gaggcgtaac ctttgatgaa gttattgatt
     5161 atattgactt tggattgcta aatggtgttt cagggatagt tataactcta atggcacaaa
     5221 ggactggaaa tgcctaccca ttggatagaa tgctgtttat gcagtgaagt ttttaagtta
     5281 aaggagaagt atgagaaaaa tcttaaaaaa caaactatat ctaaaagttc tggtttcgga
     5341 tttgatatca aattttggag atacattata ttttatagct ctcatgacct atgttacgga
     5401 gattaaggag agtaatttag ctatttcaat cgtaaatata tcggaaactc tacctatttt
     5461 atttacaata ttttttggta tcattgcaga taaaacgctt aataaagtga aaatgattat
     5521 taaaacgtta tggctacggg tgattctata tttattggtt gctgtggcta tgaattttaa
     5581 accttctatt atagtagtca taattgctag tctcgttaat cttgttgcag atacattggg
     5641 acaatttgaa aatggtcttt tttatccaat ttctaatcga atagtgaaaa agtcagatag
     5701 agaagaaact atggcgttta ggcagactgt tgtttctacg atgaatattg taaatcaatc
     5761 attgggggcg tttttaatta ctttttttag tttttctcac ttagctttta taaattctct
     5821 aacttttgct attagtctgt taattatgtt agcaatcaga aatcaaatta atagctatta
     5881 tgacgagacg atttcgacta gtaagatatc tcaatttgac tttaaagctt cattttctga
     5941 gattatttca aatttaaagc tctcgattaa ccatctattt agtatcggaa acatgaagga
     6001 agctttactt gttataccta ttctcaatgg gagtttggca attctcattc cattagttgt
     6061 tgttaatctt tctaaagatt ctaatttgac aattgttaat tctgcgatta cgatctcgct
     6121 tttaggaatt agcactgttt caggaggaat acttgggggc actttaattc taattagtaa
     6181 aaaatttaaa agcctttcca taggcacttt gctaaaaatg aatttaacga ttgttttact
     6241 atcattcgtt gctttttact tccaaaatat ttatttaatt atattatcat catttctttc
     6301 gagtgtatta gttagtgcat taaatcctaa aatggggact atcatattta ataatattga
     6361 tgagacgaag ttggctacaa tatttggagg aatggtgaca tatttccaaa taggggatat
     6421 tgtgtcaagg ttattgtttt ctacattagt gatttactta ccgtatggtt atatcgcatt
     6481 aatatatata gcagttgttt ttgtggcaat tttatataca ttaaaaagtt caaatcacat
     6541 agaaagggaa ttttaaatta gttaaatgat tatagttttc caaattttct actatgaaaa
     6601 cctattttca agattgagta ctaaagttcg agattttgtt cgtactcagc ttagagaatt
     6661 tcaatatttg gatgatgggc aatttaaaac attaccagag tatccagaat ttgcttggtt
     6721 tgaagggatg taaatgcggt aactcataga aattgctcca tttttggcga ttatatccga
     6781 attatgatgt ttgatgatcg attagaaatt tatagtccag gtaagcttcc taatatcgta
     6841 acggttgaaa atattaagca cgaacgtttt tctcgtaatc ctcgtattgc tagaacttta
     6901 acagaatttg gatgggtacg agaaatgaat gagggagtga agcgaatcta ttctgagatg
     6961 gaatcttatt tcttgcatga acctaaatac acagagccag gaaataaagt tgttttaact
     7021 cttgaaaata atattttgag ccgacatttg agagttaatg ataagatgat gaaaaaatat
     7081 gacgaattca atgatttaaa tgacgatgag aaagcaattt tacatatcat gtataatacc
     7141 ggagagaaaa tgactactgc tttggccgct agaataacaa ataggggtag aaattttgca
     7201 agtaaattat taaagagtct tgtaaataaa gagatcctgg aatggcatgg cacaagtaag
     7261 caagatagaa atcagtacta tactttggca gaatagcgga tctatttata actggagtgc
     7321 agaagagtgc agtagttcgg agtaaaacgc agtaagtgaa tttcccctgt tttcctcaaa
     7381 aaatctcaaa ctttttgaaa ttctggacaa aagaaaaggc ctagttgcct gtagtttcta
     7441 cctattaagt tatattgaaa ttcattggtt taaaaccaga tcttaagaaa gctcgtaaag
     7501 cttcacaatt ctcaaaacgt taatcaatac gattatatca atgtttcaag acattcaaga
     7561 gttatctctt gggtgtcttt ttttattcaa aattcgatag tttccaccaa agtttccacc
     7621 aattttccac cattattttt tcaagctacg aaatgcaata tcgcctactg tccgattaac
     7681 tatatctttt gtatttacat aagtctttgt aatttgctta tcactatgag ttagagcttc
     7741 tgaaatagct tcaagagaat aacctgcttg tttggcaaga gtaacacctg catgtcttag
     7801 tttgtgtggt gatgctggtg caagttctgg atgtctccgt ctgactgact tcattctata
     7861 atttagataa tccacgtgaa gaggtaaatt aatgttgttt gaacgatcat tataggtgaa
     7921 tacaaactgc ttttgagttt gacgcaatcc aaataatttt aactcctctt gttgtcttgc
     7981 tttccaatta gctaatagct caattaattc aataggtgtt ttaaaaaggg tcttcttacg
     8041 acctttggtg ggttttatat ttccgaaacg atctaaagct tgttctatca gtgtttctcc
     8101 agtagagaaa ttgatgtgtt tccattgaag agcataactt tctgattttc tatcggataa
     8161 aaagaatgtc gtataaaaga gagtgtagtc ttttaaatca ataagtcctt tctctaagtc
     8221 tatgtcaaaa gcttgtaacc ataatttcag ctcttcttta tcgagagata aatcttcctc
     8281 tcgtttgctt tctttaagga gaatcttttt attagcttta attctagtaa ttgttttgcg
     8341 gagtttattt gatggaatat attctagttc ctcagcccaa tcgaaaacag aattaacata
     8401 gctcctaatt actttgaaat tagcatagct atttgctttg ggagtaagta atgaaagaat
     8461 aagttgttta ttattatttg ggtattcgat agaatattta cccagaatgg gtaaaatgtg
     8521 tagcctgaat atattttctg tttggaaaac tgttgctttt gtgggtggtt ttattgttgt
     8581 tgtggtttga cctgctttgt atggttcgag ccaaatatct tcataaaatt ttttgaatat
     8641 gatttctcct ttatttttta tgtttatatg gctttttcca gacttagcat ttttaatgtc
     8701 gatagaaagt tttaattcta cttctttggc ttctcgtctg gttttatatt ttctttcaaa
     8761 aagtttacct aaacccaatt ttgcttgaac atcttctgga atgtaaagtc gtaattgata
     8821 tgttccattt tttgttttct taatagacat atttacctcc ttatgcgctg atttctaatc
     8881 ttgtcatcca ttgattgata cttttcttgt tgaaactaat agattttccg attcggatat
     8941 agggtaatcc cattgcaatc ccaatatcaa gtgtattatt agagatacct aggtagttgt
     9001 aagtctgttt tttgtttaga aaagtgctgt cagccccaat atcctcttta aaatgatgaa
     9061 tttcattctt tattagtgtt gcaatcattt gctgaatttc ttgagtttgt tcttctggca
     9121 attgtactag catatattat tctcctctta aaaataaaaa agaagagtaa aatactctcc
     9181 tgctgttaaa aagattaatt cttcttattt attattttgt tgaaaaaaac tagcaaagcg
     9241 accccgacca ctgtcaattg tttgccctta ttacgacatg catcacaaat tggtattgtt
     9301 ttaggtgatg agattgtttt tttacaagtt ttacacttct tcgtttttag tgtcattttt
     9361 ttctccgttt cgatttttgc tgtttcggta ttgcttaagt taacgttact atcttggtgg
     9421 aattcaatta atttagtatt aatattaata aataagtccc tattgttttt tgagtagctg
     9481 taatgattat gaattaattc taacaaactt acttttggga tactattatt ctttatccat
     9541 tttaattctt ttacataaag aagttttttt gctagttctt tcaaataatt tgttttgtat
     9601 ggaatatttt gtttagaaac taattccatc gaaccttgaa aagatagtag ccgatcatgg
     9661 gctatcccct cattatttag tgttaaatcg atataaattt gcataccaac aattttagtc
     9721 ataatttcta tgtcttgaag taaaaaatca gcatgtgttt gtaaagaggc ttgacggtat
     9781 gttggttggc tgattttctt aataatttca tctctatttg aaattatatc agatttaata
     9841 gcacttactg attcttcaaa taatgtattt gcatccttta gtgacttaac tttttctctg
     9901 aaatctttgc tattgttggc ttctataact tttgtacgag ctgaataaaa tggagctagt
     9961 atactattat ttctttccca tctaatctga taatcttgac tttctttgat atctaacagt
    10021 aagttataga tttgtttaag ttgagcttga gcgattagat cactaggaac ttgattttcg
    10081 ttgttattag tcattttcct taatgtcaaa tcttcaacac gattcttctg atcggttgtg
    10141 tctacaatta cagccctaag atttccttct acttttctag attccccaat tttataagcg
    10201 ccctcttgaa gtttcgcttt ggtgtcagga gatagactgt caaagtcaac ctcatataga
    10261 gtagcattat tgaaatctag tattttagtg ttaggattaa gatattggtt tgaaaagttg
    10321 aatggagggg ttcctttagt atcaaataag tttaagatat caaatgggaa actttcttta
    10381 atcatgttgg ggagagcttg ttcaaaagga ctacttattt caaagatatc tgttgttttg
    10441 atatctgtct catttttaaa taaatcaaaa gattgtaagt ttttttgatt gattcttctt
    10501 tttgcttttc tgatttagca acttcgttca ttagatcacc tagtcatttt tgtattaatt
    10561 ataacattta gtattgattt taaacgtatc taaattaata atactaaaaa ttaatattat
    10621 taaaaccatc atcagtgtcc aatgacataa gtaatttgtt ttgctgtttc tgcatcaaaa
    10681 gtgcggtagc taacgactcc tagtcctttg atatttgatt cagagatgag gatggagcca
    10741 tctgatttga cttgttccac aaaggcgatg tggccataag ttggatctgc tccagcttgc
    10801 cctgggctaa aagatagagc ggagtgttcg gttggggtat gagttgtctg ataccctggg
    10861 gcattcatcc attggccacc atttcccata tactttccga agctaacacc gacttctttt
    10921 cctcggttat agacaaacca ggtacattgt ccccaaggat aagacagtcc tgtgtggctt
    10981 gaggtattga tttctttggt gaggctatag ccttgtggga catcccctgt tgtgacaccg
    11041 cctccgtctc tggtttttcc tttcgtctgt tcaggggctt ttggtgtacc tccatgctca
    11101 tcgatatagg tatcgagttt ttgcatggtt tcagcacgcc ctttcctaga gccagaggta
    11161 tcggtgaagt agacgccacc atctgttgac gtgttgagag aaccactcgc aaatttttgc
    11221 gctttgtcat cttggacttt taaggtttca tttttattgc caatgatggt ctgctttgtg
    11281 agtccaacaa cggctacttc atcgttaaaa ttattggcat tttctggatt agagtcaaat
    11341 gcggttctgt tgcaaagttt taaataaaga ataaaatccc ttacggtatc tatgatttaa
    11401 gctgggattc ccaataatac cttgatttca gtacagaccg aaaacccgaa gagagtgcct
    11461 tcttttcgag ttttcttata taatcctcgg atggcttcca tgcctttaat cgtggtagag
    11521 gcagtgcgta aacttcgata gaatttattg tgtctcttta ctggacgatg gtcttgttca
    11581 atcaaattat tcaggtattt aatggtacaa tgttctgtcc cttgataaaa gccccgtatt
    11641 ctcttagttt cttaaaggca cttgtaatag agggggcttt atctgtgact acaaccttcg
    11701 gttcatcaaa ctgcttaact aaccgctcaa gaaaagcata ggctgtttgt gtgtcccgtt
    11761 ttttacgtaa ccaaatatcc aaggttaaac catctgcatc gatggctcga tacaaataat
    11821 gccattttcc tttaattttg atgtatattt catccatttt ccatgaataa aaggattttt
    11881 tatttttctt tttccaaatt tgatagagta gtttgccata ttcttgcacc caacgataaa
    11941 tcgtcgtatg agaaacgtta atgccacgat catataagat ttcttgaact tcacgatagc
    12001 taaggttata acgaagataa tagcccacgg ttacaataat cacatcctgc tgaaattgct
    12061 ttcctttaaa atgatttatc gtcattcctc ctgctatctt tttctattat tctacctgat
    12121 ttgatagtag atttaaaact ttgcaacaga accgatgtaa ccgtttatta atctttttta
    12181 tcatctatgg ataacatttt tttgttacac taggagtatg aaaaaggaga tatgatgaaa
    12241 cagagccaag ctaaaaagca tgacaatacg atgactaata agattttgat gaggttgatt
    12301 gctcttgtct taggtttgct ttttcttgaa attttgatta ttcatagtaa aaatgagcag
    12361 caaaagagtg tttcaaatca agtacagaca gcacgtatca tggctaatgg ggacttgctt
    12421 tatcatgacg gtctctatat gagtgccttg caggcagatg gcagttatga ttttactgaa
    12481 aattttacat atgtgaagcc atggttaaag caggctgatt tggtcttggg tgattttgag
    12541 ggaactatca atcctgatta tcctttgtca ggctaccctc tgtttaatgc tcctcaatca
    12601 gtgacggcag ctattagtga tgccggctat gatgttatgg atttggccca taatcatatt
    12661 ttggactctg gtttagaggg agcttttaca acagccgatg catttaaaga ggtgggcatt
    12721 gaccctgttg gtgtttatga aaatcctgtg cgtgataagg cgcctctgtt tatcaagaat
    12781 gttaatggca tcaaggtggc aatactttct tatgcctatg gtttcaatgg cttggagtca
    12841 aatctgaccg aaaaagagat tgcgaatcat ttgtcgaatc ttgatgaaaa acggatgaaa
    12901 gtagagattg agcgtgctga aaaagaggct gacgttacgg ttattatgcc acagatgggc
    12961 gtggaatatc gtttggaacc gacagatgaa caggtaaagc tttaccataa gatgattgat
    13021 tggggtgctg atattatctt tgggggccac cctcatgtgg ttgagccgtc tgaagtggtt
    13081 aaaaaggatg gacagcaaaa actcattatt tactcaatgg ggaatttcat ctctaaccag
    13141 cgcatagaga ctatggatgg tgtggatagt gcagcatgga cagagagggg cgtcttaatg
    13201 gatgtcactc ttgagaaaaa gaattgtcaa accacgatta agacagctca agcgcatcca
    13261 acctgggtta accgcacacc caagggaaca atttcgccag agggatatcc tttatatact
    13321 tatcaaacct atattttaga ggatttcatt aaaggtggaa aatacagaaa taaactagat
    13381 gaagaaacta aagagcgtat agatactgcc tataaagaaa tgaatgctca tgttaatcta
    13441 aaatggaaat aaagctaaga tatcgctaaa atttggcgat atttttcttt atcgacaagt
    13501 taccaacaga cttatccaca ggtgtggata agtctgttct cagtgttaaa ccttgatttt
    13561 tcaaggtttt attagaattg tattgtttta cttgttaaca agtttatcca caagttgttg
    13621 aattgataga gactgaattt tataaacgat actggttaaa tgttgtagaa acattcgttt
    13681 ttttcaataa aaaaggtgta atttctataa aaaatagcgt ttttaatcaa aatatgctaa
    13741 aattatataa aataaaatga tggaggcttc tcatgaaagc gattattaca gttgtaggta
    13801 aggataaagc gggtattgtt gcaggtgttg cgactaagat cgcagaactt ggtttgaata
    13861 ttgatgatat cactcaaaca atccttgatg aattctttac catgatggcg gttgtatcat
    13921 cggaagataa gaaagatttt acacacctac gtgctgaatt agaagctttt ggtgaatcat
    13981 taaacgtcaa aatcaatatc caaagctcag cgatttttga tgctatgcac aacttataag
    14041 ataggggtag ttgaaaatgg atattaaaca ggttacagaa accattgcta tgattgagga
    14101 gcagaacttt gatgttcgta ctatcaccat gggaatttca cttctagact gtatcgattc
    14161 agatattgat aaggcagcag aaaaggtata caacaagatt gtttctaagg ctaagaactt
    14221 ggtagctgtt ggtgacgaaa ttgcggctga acttggtatt ccgattgtta ataaacgtgt
    14281 ttctgttact ccgatttcaa ttatcggtgc ggcgacagat gcgacagatt atgtaccgtt
    14341 tgctagggca ctagaccgtg cagctaagga aattggcatt aactttattg gtggtttctc
    14401 tgcattagtt caaaagggct accaaaaagg tgatgagatt cttattgatt ctatcccacg
    14461 tgcgcttgct gagactgatt ttgtctgctc atctgttaat attggttcaa caaaaactgg
    14521 tattaacatg acagcggtac gtgatatggg acgtatcatt aaagaggctt ctgaggcaga
    14581 tccaatgggt ccaggtaaat tggttgtctt tgctaatgcg gttgaagata atccatttat
    14641 ggcaggtgcc ttccacggtg ttggtgaggc tgacgttgta atcaatgttg gggtttcagg
    14701 tcctggtgtt gtgcaacgtg ctgttgagaa ggtttcaggt gaaagttttg atgttttagc
    14761 tgaaacagtt aagaaaactg cctttaaaat cacacgtgta gggcagttgg ttggtcaaat
    14821 ggctagcgaa cgtctaggtg tcgagtttgg tattgtagac ttgtctcttg caccaactcc
    14881 agcagtaggt gattcggtag ctcgtgtact tgaagccatg gggcttgaag ttgttggtac
    14941 gcatggtact actgcggctc tagctcttct taatgaccaa gttaaaaaag gtggtatcat
    15001 ggcatgtaac caggtcggtg gtttgtcagg tgcctttatc ccagtttctg aagatgaagg
    15061 aatgattgca gcagttcaat ctgggcatat caaccttgaa aaattggaag ccatgacggc
    15121 tatctgttct gttggtctag acatgattgc cattcctgct gatacgccag atacaacaat
    15181 tgcggccatg attgccgatg aagcggctat tggtgtcatt aatcagaaaa caacagctgt
    15241 tcgtattatt ccttatggta aggaagg
//
