LOCUS       c00021_JAIQWP0..       13507 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIQWP010000029.1 Streptococcus thermophilus strain DS45_14
            NODE_29_length_16720_cov_22.001680, whole genome shotgun sequence.
ACCESSION   JAIQWP010000029
VERSION     JAIQWP010000029
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:32:49
            Original ID  :: JAIQWP010000029.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13507
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13507
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1347:3507](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1348..3507
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..13507
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13507
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             111..230
                     /locus_tag="ctg21_1"
                     /transl_table=11
                     /translation="MSIRFRKEKKMTTQNLNKLPGTIAVPMDKIRITIYCPSF"
     CDS             391..1263
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_2"
                     /sec_met_domain="TIGR01716 (E-value: 1.2e-31, bitscore:
                     100.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTIDIGSLTKKIRLSKKLSLKDVAGDYLSVSFLSKFERGESEI
                     SLSRFLCILENLDVSIEEIYGILSKDNPTRTEELLARVSKAFQQNNIPALKKYYYEEIE
                     KFNSTHKKIFLYNSILIDSFLISITGKKMNKKHIEVISDYLFDVDQWGKRELVILGNSM
                     SAVPTNTLNLLIKEIIYKTTLFGNNEENKKIKIDLILNGISIFLERKELNYAKFYIDLF
                     DTLTIPEVYLYERVEYNILIGTYWILIGKIEVGKKKIELALESLKNLGAENLLLMRENE
                     YEELLNSII"
     CDS             1348..3507
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_3"
                     /sec_met_domain="LANC_like (E-value: 1e-08, bitscore: 24.7,
                     seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 7.2e-15, bitscore: 45.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELITPSEKRIINRKKGEIYDYISYSNAFVPYQGWKIHISANLI
                     DYQSILDNVYHVCSIFQTPFKYINKISELFRILSKHVSQLEIGKFITIYPKNKETFLLL
                     LEELYDKIPKYTGVQILTDRSYKDSEIIFYRYGVMNARLINNERPKLKFNGTFYEDITE
                     PYYTCPPFVEDIIFNKVVDDYNIESLFHDRYQMESIIHKSGAGNVYIAIDTINEEKVII
                     KEARKKVYITEKILAIDLLLNEKCILKKLKGKVDIPNYIECFTIEGNLYLVEEFIDGQR
                     LDILKPEYNLLIKRNSSELGRYNKKVKKIISNLFLSLYKIHQEGIILEDISSSNILLTN
                     DDRVFFIDLETAYNKNDGIIVETTNECYPKNISQKNEQRDIVKMWYCIIDLLTNSTSLL
                     KYDNTGVSTLNLFYKMSLENNLPKSLRKKFINDFSIVDFKNTFIIKFIEMGLNIEKIVR
                     MQQDLTETILSHNTFEIYGKTILESIDNYKHISNMDLKFSSDPSFSSLYDNCNKSIDDL
                     IGIAILDNNFELFLNCNLDELLHNMSYYQKYYLLRLFNDTKICDRVYFIKVLNSIIKND
                     IKCIDGVKYIKSNEYFSPYLITGNSGLIIELIKFSKNNNTMKFDEWIRSLSEGISYTYA
                     KGTSLYYGLAGLGLANAWLYYYFKETSFLKTSIKICEHIFDFSIKQNTKTILIDPMSEE
                     IDYTYSKGMLGQLYFINELLNIIKE"
     CDS             3512..5080
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 125; E-value: 6e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_4"
                     /transl_table=11
                     /translation="MKKYILKYKLLNLIHIILIGFSSAFLVGASVTLSIMLNKLVESDF
                     KGFLIWLGIEFGVYLLFLADTYLIRVNQTKLIQKMTLSLRDDYINSLTRKSFSEFKNKT
                     VGEHLSILNNDIKIIEESGFESFYSLVSTVFTTFFSIIALFSYDYRIVLLSILLTLILT
                     YLPRSFAHKMEKAMKRFSIGNETFISSLTDQLLGYDTLYYSNKKEMLSIKCGEVIKKFI
                     FEKIVFIKTSSLIEIIMSLFSIISQMLVLLLTGYLIILKQVSIGSISSVGQISGNIFNS
                     LTTFNQLQVSISSVNIIFEKFGAFEKSSHYRYIDKDIEEIKLTNVGYSFKDKEIFKNIN
                     CSFEKGKNYAIVGESGSGKSTLINIILGNNKQYSGSVKYNDVEISDIEESQLFKSVSYI
                     GNITHIYHDSLRNNLTLWDNKINESEIINILKQVNLIDLIPRLDDEVSMSFLSEGQKQR
                     LGIARAYLTKTNVIIMDESMANLDRDNAFLIENQLLNDPTRMYITVSHHLQEKLLDRFH
                     SIITL"
     CDS             5835..6029
                     /locus_tag="ctg21_5"
                     /transl_table=11
                     /translation="MKYGKIFKKFRESRGLSLKNVAKSGLSSSHLSRFENDEADLTISN
                     FFSVRCNTYAYRRICLRCT"
     CDS             5995..6693
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_6"
                     /sec_met_domain="TIGR01716 (E-value: 6.6e-49, bitscore:
                     156.7, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIEEFVYAVRDFRRDDFNELLEKIRYLVSNRDIDGMKKLLISQM
                     EKKDKKEPFASFNTILIKIRLQDLSGETYVTDQEIVTISDYLFSAEYWGYYELLLFMNT
                     IDALNHNTMMILAKEMCHRLDFYRDIPNNRRLLATMLLNAYITCIERNEWMDALYFEKQ
                     LKYCNFSETEMYEKLVLHYANNLYDLKKNNNRHAVLEMRKCIAATKLVDSNQISIKFEN
                     YLQKVLDDMR"
     CDS             6771..6878
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MEKLQVIDLEELLEFDQGYVINASCGPSHSCGGGR"
     CDS             7153..8133
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_8"
                     /sec_met_domain="Fer4_12 (E-value: 4.2e-09, bitscore: 27.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLTTADNIIQEIASKGVTQINRLILFGGEPFLNIELFIYFIEKL
                     STLLNVVKIETVTNGTVLNKRVKEMLVKFHPYLTISLDGPEIVHDRLRGRGSHRKTLRF
                     INYLKNIDYENFEIASTYTRLHQKNGLSREDIFQYFTDMDVHFNINDVFTKNKVLIVKE
                     MEKSLAERKQFIDKSIQHVINNNEKAFISPILYDVLISMIYKSTNRTFCDDIDPSNTLT
                     YDVDGSKKLCFRFWGTHNSPKAESFNNKDNFEKCKNCWCRGMCLECVANVIDGYSSVIS
                     EDGEFLECSKPELMEYCIKQIIYLSKDREKLSRLVNNFRGFIRYA"
     CDS             8126..9667
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 150.2; E-value:
                     1.4e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MLRSYVTKKHLTFYFLAIVITWLEAIITPALIQYIVASFTNRQLH
                     LLWQILLWGIGGNLVLVLGLAGKRYYYARLMTDFKVGIKRAIFRTFLYSRQIPDEEVLS
                     DLENDVQQLENSYIEPTVIIVSSLGFTVVSIAYALWTNFYLGLLFIIFYSVPVLCSGLG
                     SKRLDRIAEQKSLANQNYIARVNNMIAGVAPIRHYQGQNLFFKRFSKDLEQALQEEVSY
                     EKQRSLNSLFINSIDAFCSVAPIVIGGFMTYQNYLSAASFVGIYLVSHNIGYQFQELSY
                     FINTRKSAKSLCDKYQDLFGNKLATDSIFDQSVFPIQLEQVSVEKDGETILAPCDLTIH
                     AGEKIAIIGESGAGKTTLLNILYGEIHPSQGQIRYQGRELTSCQLYQAGAYILQSSHVF
                     DDLSVEENIALGQEIDQQRMDNILQETGLLSLKGKVPSNQTLSGGEKQRLEIARALYHK
                     RQFILADEVKANLDAKNQEKINQLLFSLPQAVVEVIHHYTKEDLKRYDKVIHLKK"
     CDS             complement(10071..10583)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 56.5; E-value: 7.2e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MTFIIQNFGPNLARLRIEKGVSQTQLAEYLGIGKQSISDYEKQKS
                     YPTFANLDKIAEYFNATPTQLFGTSKEIELEKSVLESNEYSDKVSEILKAVKYIENFLE
                     TDGQYLEDLLYLTRGKQLYTEDGDELYTDPTSQKRTFHNQYEPGFIVARDKSPLELLIE
                     NKELFDK"
     CDS             10992..11348
                     /locus_tag="ctg21_11"
                     /transl_table=11
                     /translation="LLISIQDLRSIQERCEIGELVQRLDVSIDRLTVIWDTDTGPLRRI
                     FKNLKQAISTRVDSFEIHDNVRDDVFTLAKDFNEYDSINIIFFQLSTYGGEQLIRIDFN
                     PNTLKEFDGMKVWR"
     CDS             11352..11969
                     /locus_tag="ctg21_12"
                     /transl_table=11
                     /translation="MYFARLNSLTVRLSRFDLAFDIFNRPEIVNLQHIKGGVTHKVFYG
                     RGGELETKYWGSSGSNVQVRLYDKNKEIIAHKHEEKLDLGVNPFWWRLEFQLRTKAIGE
                     DMVQDIMNRLDNFGFYKLEHIRVDQRAFTIIFLSNPELLSLAFPNLKSDSIKKKKTRVR
                     KLLREETNQFAEELKEVLIQNLPKLNTELQLLVGEFLTLENQ"
     CDS             11981..12169
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="MDNNLISNKELIEMGYRPHTANDIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVNEILGTEVA"
     CDS             12171..13310
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 86.3; E-value: 5.4e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg21_14"
                     /transl_table=11
                     /translation="MASVLYRKRGDSNLWTYEIRNEGKTVAHNSGFKTKKLAESEAEPI
                     LQELRLGKRISRDISLADLYQEWLELKILPSSRSEETKKKYLLRKNTIERLFGNKKVTQ
                     IRASEYQRIMNKYGQTVGRNFLGRLNTGIHQSIQMAIADKVLIDDFTQHVELFSSKEQQ
                     MTEEKYLHTEKDYLDLLLAVKRKFDYQRSIVPYIVYFLLKTGMRFGELVALTWNEVDFD
                     RGLLKTYRRYNTLSHKFVPPKNKTSIRMVPIDEECIKILRLLQTEQERANMELGIKNRY
                     RMIFQHFGYIHSVPDIASVNKALSVLLNELDIYPIITTKGARHTYGSYLWHKGFDLGVI
                     AKILGHRDISMLVEVYGHTLEEKIFEEFNQIRDIWKDCS"
ORIGIN
        1 tgattaacat tcttcaactc tacttgagtg tttacacata attattgaca gtatcgggca
       61 attcctatat atgaaaatat taatacttaa ttattgcaaa aatatataat atgtctataa
      121 gatttagaaa ggagaaaaaa atgactactc aaaacctaaa taagttacca ggaacaattg
      181 cagttccaat ggataaaatt cgtattacga tttactgtcc aagtttttaa ggagaaaaat
      241 gattattcaa attttgaaca gtttaccaag tgattctttt gaatttaaag atagacttcg
      301 tattacaata tactcctaat attcaaaagg ttaacgcaga ctgcactatg tttgcgtttt
      361 ttgttataat tgtataaaag gagttatttt atgattgata ctattgacat aggttcttta
      421 acgaaaaaaa ttagattatc aaaaaaactt tcattaaaag atgttgctgg tgattatctt
      481 tcggtttcgt ttttatctaa gtttgaacgt ggcgagtctg agatttcact ttctcgtttt
      541 ctttgtatat tggaaaattt ggatgtaagt atcgaagaaa tttacggaat tttatcgaaa
      601 gataatccta caagaactga ggaattacta gcaagggtca gtaaggcatt tcaacaaaat
      661 aacatacctg ctctaaaaaa atattattat gaagaaatag aaaagtttaa ttcaacacac
      721 aaaaaaatat ttttatataa ttctattttg attgattcat ttttaatatc gataacaggt
      781 aaaaaaatga ataaaaaaca tattgaagtt atttctgatt atcttttcga tgtagatcaa
      841 tgggggaaaa gagagttagt aatattaggt aatagtatgt cagcggtgcc tacaaataca
      901 ttaaatttat taataaaaga aattatttat aagactactt tatttggtaa taatgaggaa
      961 aataaaaaaa taaaaattga tcttatttta aacggaatct caatattttt agagaggaaa
     1021 gaactaaatt atgccaagtt ctatattgat ctttttgata cacttaccat tcctgaagtt
     1081 tatctctatg agcgagtgga atataatata ttaataggta catattggat acttataggt
     1141 aaaatagaag tcggcaagaa gaaaattgaa ctagctttgg aatccctcaa aaatttaggt
     1201 gctgagaatt tactgctaat gagagaaaat gaatatgaag aattattgaa ttctattata
     1261 tgacactttt tactaaaaat aaaatactgc tgttacacta gttatatagt tatacagcag
     1321 tattttattt ttaataggag atttatcatg gaagaactaa ttacaccaag tgaaaagaga
     1381 atcattaata gaaaaaaagg ggaaatatat gattatattt catattcaaa tgcttttgtt
     1441 ccttatcaag gttggaaaat tcatatatct gctaatttaa tagattatca gtctatttta
     1501 gataatgttt accatgtttg ttctattttt caaacgccat ttaagtatat caataaaata
     1561 tctgagttat tccgtatttt atcaaaacac gtttcgcaat tagagattgg aaaatttata
     1621 actatatatc ctaaaaacaa agaaactttt ttattattat tggaagaact atatgataag
     1681 atacccaaat atactggagt tcaaattttg acagatagaa gttataaaga ctcagaaata
     1741 attttttata gatatggagt aatgaatgca cgtttaatta ataatgagcg accaaaactt
     1801 aaatttaatg gaacctttta tgaagatata acggaaccat actatacatg tcccccattt
     1861 gttgaagata tcatatttaa taaagttgta gatgactata atattgaatc tttattccat
     1921 gatagatatc aaatggaatc tattattcat aaatcaggag caggtaatgt atatattgcg
     1981 attgatacta ttaatgaaga aaaggttatt ataaaagaag ctagaaaaaa agtatatatt
     2041 acagaaaaga ttttagcaat agatctcctt ttaaatgaaa aatgtattct aaaaaaattg
     2101 aaaggtaaag tcgatattcc aaattacatt gagtgcttta caattgaggg aaatttatat
     2161 cttgttgagg aattcattga tggacaaaga ttggatattt taaagcctga atataatttg
     2221 ttgataaaac gaaattctag cgagttagga agatataata aaaaagtaaa aaaaataatt
     2281 tctaatctat ttttaagttt atataaaatc catcaggagg gaataatatt agaggatata
     2341 tcttcaagta atattctttt aacaaatgat gatagagtat tttttattga tctcgaaacc
     2401 gcatataata agaatgatgg aattattgtt gagacgacaa atgaatgcta tcccaaaaac
     2461 atttctcaaa aaaatgaaca gcgagatatt gttaaaatgt ggtattgtat aattgattta
     2521 ttaactaatt ctactagtct tttaaaatat gataatacag gagtgagtac cttaaattta
     2581 ttttataaaa tgagtttaga gaataattta cctaaatctt taagaaaaaa atttattaat
     2641 gattttagta tagtggactt taagaataca tttataataa aatttattga aatgggttta
     2701 aatatagaaa aaatagttag aatgcaacaa gatttaacag aaactatact ttcccataat
     2761 acttttgaaa tttatggaaa aacaatatta gagtcaattg ataattataa acatattagt
     2821 aatatggatt taaaattttc tagcgatccc agtttctctt ctctttatga taattgtaat
     2881 aaaagtatag atgacttaat cggaatcgct atacttgata ataattttga acttttttta
     2941 aattgtaatt tagatgaact actacataat atgagctact atcaaaaata ttatctactc
     3001 agacttttca atgacactaa aatatgtgat agagtctact ttataaaggt cctaaattca
     3061 atcatcaaaa atgatattaa gtgtattgat ggagtgaaat atataaaatc caatgagtat
     3121 tttagcccat atttaataac tggtaactct gggttaatca ttgaacttat taagttcagt
     3181 aaaaataaca atacaatgaa gttcgatgaa tggattagaa gtttatcaga aggaattagt
     3241 tatacatatg ctaagggaac ctcattgtat tatggattag caggattggg tttggcaaat
     3301 gcttggcttt attattattt taaagaaact tcatttctta aaacgagtat taagatttgc
     3361 gaacatattt ttgatttttc tattaaacaa aatacaaaaa ctatattgat agacccgatg
     3421 tccgaagaaa ttgattatac atattcaaaa ggaatgttgg ggcagttgta ctttattaat
     3481 gagttgctaa atataattaa ggaataacat aatgaaaaaa tatatactaa aatataaact
     3541 gctaaatctt atacatataa tattaatagg atttagttct gcatttttag ttggagcatc
     3601 agtcacactc tcaatcatgt taaataaatt ggttgaaagt gattttaaag gcttcctcat
     3661 atggttaggc attgaatttg gagtttattt gttatttttg gcagatacat acttaattag
     3721 agtaaatcag actaaattaa ttcaaaaaat gactctttct ctcagagatg attatattaa
     3781 cagtctaact agaaaatcgt ttagtgaatt taaaaataag actgttggag aacacttgtc
     3841 aattttaaat aacgatataa aaattatcga agaaagcgga tttgaaagtt tttattcatt
     3901 agtttcaaca gttttcacaa cttttttttc aattattgct ctgtttagtt atgattatag
     3961 aatagtgctt ttatctatac tacttacttt gatcctaact taccttccac gaagttttgc
     4021 ccataagatg gaaaaagcta tgaaaagatt ttctataggt aatgaaacat ttatttcatc
     4081 actaacagat caattactgg gatatgatac gctatattat tcaaataaaa aagagatgtt
     4141 atcaattaaa tgtggagagg taataaaaaa atttattttt gaaaaaatag tatttattaa
     4201 aactagtagc ttaattgaaa taataatgag tttattttca attatttctc aaatgttagt
     4261 actactttta acaggttatc ttatcatttt aaaacaagtt tcaattggtt caatatcatc
     4321 agtcggacaa atttccggaa atatatttaa ctcattaact acgtttaatc aattacaggt
     4381 atcaatatca tcagtaaata ttatatttga aaaatttgga gcttttgaga agagttccca
     4441 ttatagatat attgataaag atattgaaga aatcaagtta actaatgtcg ggtattcctt
     4501 caaagataag gaaattttca aaaatataaa ttgtagtttt gaaaaaggaa aaaattatgc
     4561 catagttgga gagtcaggta gtggaaaatc aactttaata aatataattt taggaaataa
     4621 taagcaatat agtggaagtg taaaatacaa tgatgtagag atatctgata ttgaagaatc
     4681 tcaattgttt aaaagcgttt catatatagg aaatattact catatttatc atgattctct
     4741 tagaaataat ttaacacttt gggataataa aataaatgaa tcagaaatta tcaatatcct
     4801 taaacaagtt aatttaatag atttaattcc acgattagat gatgaagtaa gtatgtcttt
     4861 tttatcagaa gggcaaaagc aaagattagg tattgcacgt gcctatctta ctaaaactaa
     4921 cgtaataata atggatgaat ctatggcaaa tttagataga gataacgctt ttctaattga
     4981 gaaccagcta ttaaacgatc ctacaaggat gtacattact gtctctcatc acttacagga
     5041 aaaactacta gatagatttc atagtattat tacactttaa attgagaatt caatgttact
     5101 atacacaaca aaaattaatt tatacaaaaa taatatttat caaaagtttg gaaattattt
     5161 cggggacaaa tgatgggaca tttcctcttt agacaagtaa gaaagccttt atttaaaggc
     5221 ttttttatgt atagtatgat gccccctaca tgaatttgta tgaatttttc atattgaaaa
     5281 taatcaaaaa tgttgaaata taagttattt ttagaagata cttggagcat ttttaaatat
     5341 aattatttca aaatggggca aaagtggggc aaaaacgaat gactcataaa ggtttccaac
     5401 ttgctttgaa aaccaggctt gaaaaaggct cgtaaagcat cgaaatttag taaacgttaa
     5461 aactgattta cacttattga aagcatttcg tatccaaaat acgggattct ttttccataa
     5521 aatcaagaga ggttgggcaa aaactacaag tttacccttc tgattaaaat tttaataacc
     5581 aaaaatagct tggaatcaac gtttataatg acgcaattct aagctatttt ttatttttaa
     5641 ggtttcttgc ctaatctctt tatcatttgg ctaacctact ccgataacga taataccttc
     5701 aagtattaca aacaacaaac taaacaatgc ttttttattc atggtaaata cctcttttcg
     5761 ttttcttata tgatataata tttttaatat ttgtgaagaa atttccctta taagcaattt
     5821 aggaggtgac tagaatgaaa tatggaaaaa tttttaaaaa atttagagaa tctcgaggtt
     5881 tatctttaaa aaatgttgca aaatcaggtc tttcaagttc ccatctctca agatttgaaa
     5941 atgatgaggc tgatttaacc atcagcaatt tttttagcgt tagatgcaat acatatgcct
     6001 atcgaagaat ttgtttacgc tgtacgtgat ttccgcagag atgactttaa tgaactttta
     6061 gaaaagattc ggtatttagt atcaaatcgt gatatagacg gaatgaaaaa gctattaatt
     6121 agccaaatgg aaaagaagga taaaaaggaa cctttcgctt catttaacac aattttgatt
     6181 aaaataagat tacaggattt atcaggagaa acttatgtaa cagaccaaga gattgttact
     6241 atcagtgatt acttgttttc tgcggaatac tggggttatt atgaattgct actgtttatg
     6301 aatacaatag acgctttaaa tcataacaca atgatgattt tagccaaaga aatgtgtcat
     6361 cgtttggatt tttatagaga tattccaaat aatagacgtt tattggcaac tatgttgctc
     6421 aatgcttata tcacctgtat tgaacgcaat gaatggatgg acgctcttta ttttgaaaaa
     6481 cagctaaaat attgtaactt ttcagagact gaaatgtatg aaaaactagt gctccattat
     6541 gctaataatt tatatgatct aaagaaaaat aataatcgac atgctgtttt ggaaatgaga
     6601 aaatgtattg ctgccacgaa attggtagat agcaatcaaa tatctataaa atttgaaaat
     6661 tatttacaaa aagtattaga tgacatgagg tgaattgcgt ataagggaaa atattatcct
     6721 cttctgataa ggttatataa tgaaactatc aaataaagga ggtaaaaacc atggaaaaac
     6781 ttcaggtgat tgaccttgaa gaacttttag agtttgatca agggtatgta attaatgcta
     6841 gctgtggtcc aagtcattct tgtggcggtg gtcgatagct tcttccgaga tgaggagtga
     6901 ttcctcatct cagtttttag tctggaggat aattataata aagacaatag aaacagatat
     6961 aggaacatat tattttgatt ctgttaattt tactttatct ttgtcaccta tttcaaaaca
     7021 aagttcacca actctagatt ctgttgaaga tggtgtatta aaaaagtagt tataaatatt
     7081 tctaatagtt gtaatttatc ttgttcgtat tgttatgcag atggtggtaa ctatggtatg
     7141 gataatcgta ttatggattt aactactgct gataatatta tccaagagat agcaagtaaa
     7201 ggagttacac aaatcaaccg tctcatactt ttcgggggag aacctttttt aaatatagaa
     7261 ttatttatat attttataga aaaattatct acattattaa atgtagtgaa aattgaaaca
     7321 gttactaatg gtactgtttt aaataagcgt gttaaagaaa tgcttgttaa atttcatcct
     7381 tatttaacca taagtttaga tggaccagaa attgttcatg atagactcag aggaagaggg
     7441 agccatcgaa aaacattacg ttttattaat tatttaaaga atattgatta tgaaaatttt
     7501 gaaatagcct cgacatatac tagacttcat caaaaaaatg gtctaagtag agaagatatc
     7561 tttcaatatt ttactgatat ggatgtgcat tttaatataa atgatgtttt tactaaaaat
     7621 aaagtgctaa ttgtgaaaga aatggaaaaa agtttggctg aaagaaaaca gttcatagat
     7681 aaatccattc aacatgtaat caacaacaat gagaaggcat ttatcagtcc tattttatat
     7741 gatgtattaa tatcaatgat atacaagagt acgaatcgta cattttgtga tgatattgac
     7801 ccttcgaata cattaactta tgatgtagat ggtagtaaga aactatgttt cagattttgg
     7861 ggaactcaca acagtcctaa agcggaatca tttaacaaca aagataactt tgaaaagtgt
     7921 aaaaactgct ggtgtagagg tatgtgcttg gaatgtgttg ccaatgttat tgatggatat
     7981 tcttctgtaa ttagtgaaga tggggaattt cttgaatgct ctaaaccaga actgatggaa
     8041 tactgtatta aacagattat atatttatcc aaggacagag aaaaattatc taggttggta
     8101 aataatttta gggggtttat acgctatgct taggagttat gtaacgaaaa aacatctcac
     8161 cttctatttt ctagccatcg tcatcacttg gttagaggcc attatcaccc ctgcccttat
     8221 ccagtatatc gtcgctagtt ttaccaaccg ccagttgcat ctcctctggc agattttgct
     8281 ctgggggatt gggggcaatc tggtgcttgt cctgggcttg gctgggaagc gctattacta
     8341 tgctcgtttg atgactgact ttaaggttgg gataaaacgc gctatttttc ggactttttt
     8401 atacagccgt cagattcctg atgaggaggt gctgtctgat ctggaaaatg atgtccaaca
     8461 gttggaaaat agctatatag agccgaccgt cattatcgta tcctcgctag gttttacagt
     8521 cgtttccatc gcatatgccc tctggaccaa tttctatctg gggttattgt ttatcatctt
     8581 ttactcggta ccagttttgt gtagcggact gggttcgaag cgtttggata ggattgcgga
     8641 gcaaaaatcc ctagcaaatc agaattatat cgcccgtgtc aacaatatga ttgcaggtgt
     8701 tgctcctatt cgtcattatc agggccagaa tttgtttttc aagagatttt ctaaagacct
     8761 agaacaggcg ttgcaagaag aagtgtccta cgaaaagcaa cggtcactga acagtttatt
     8821 tatcaacagt atagatgcat tttgctctgt ggcgcccatt gtgattggcg gattcatgac
     8881 ctaccagaac tacctttctg cggctagttt tgtcggcatt tatctggtct cccacaacat
     8941 cggctaccag tttcaagaac tgtcctactt tatcaatacc cgcaagtctg ccaagtccct
     9001 ctgcgataag tatcaagact tgtttggaaa taagttggct actgacagca tatttgacca
     9061 atctgtcttt cctatccagt tggagcaggt cagtgtggag aaggatgggg agaccattct
     9121 agctccttgt gatctgacta tccacgctgg ggaaaagatt gctatcatcg gagaaagcgg
     9181 agcgggcaaa accaccctgc tcaacatcct atacggggaa atccatccta gtcaggggca
     9241 aattcgttat caaggacggg aactaaccag ctgtcaactc tatcaggctg gtgcctatat
     9301 cttgcaatct agtcatgttt ttgacgattt atctgtggag gaaaacatcg ctctgggaca
     9361 ggaaattgac cagcaaagaa tggataacat cttgcaagaa acagggctcc tcagcctaaa
     9421 aggcaaggta cccagcaacc aaactttatc aggcggtgaa aaacagcgcc ttgaaatcgc
     9481 ccgtgctctc tatcacaagc gacagtttat cctagcagat gaggtcaagg ctaacctgga
     9541 cgccaaaaat caagaaaaaa tcaaccagct gctcttttca cttcctcaag ctgtggtgga
     9601 ggtcattcac cactacacca aggaagactt gaagcgctat gataaagtga ttcatttgaa
     9661 aaagtagtta tgccaatagt gtctatagac aaattgtata tctgaaaggc tctttgtcaa
     9721 ctgtcttgag ttgatgaaaa gctaacatcg agagaggaca caattcgttc tctcttttct
     9781 tatcttcaaa gtgataagaa tgcgtttttt aaagttttca aagttcctaa aatctcattt
     9841 agaactattt ggaattgtgg atacaaagca accattgact aaataattaa tgaattgaat
     9901 gagtatttag agtatttatt tttaactcaa aattgattaa aatcttgcgt aagcccaaag
     9961 aactgggaag aagcgaccgt gacggatatt tggagagagg atttatctaa aaaactagaa
    10021 aataagttat ttctttcata acagaaaaag cgagttcaaa ctcgcttttt ctatttatca
    10081 aataattcct tattttcaat caagagttct agtggagatt tgtctcttgc tacaataaaa
    10141 ccaggttcat attggttatg aaatgttctt ttctgagaag ttggatcagt atacaactcg
    10201 tctccatctt ctgtgtatag ttgtttgcct cttgttaggt aaagtaaatc ctctaagtac
    10261 tgtccatcag tttctagaaa attttcgatg tatttgacag cctttaagat ctcacttact
    10321 ttatcagagt attcattcga ttcaagaaca ctcttttcta attcaatctc tttactagtt
    10381 ccaaatagtt gggttggagt tgcattaaaa tattctgcta tcttatccaa atttgcaaag
    10441 gtaggatagc ttttttgttt ttcgtagtca gagatggatt gtttaccgat tcctaaatat
    10501 tccgcaagtt gagtttgact tactcctttt tctatgcgta gtcgtgccaa attgggtcca
    10561 aaattctgaa taataaaggt catgataaac tcctatgttg tgttttaaac ttattctatc
    10621 acctataaac ttacaaatca agtttttagt tgactgctca aaatattttt taaatgatac
    10681 aaatagctca tatgtttagg aatagtgagt gaggaggaat ttgaggacga gactatgact
    10741 atgactgatg actattcgaa gccttggagc tagaaattgt gtggacaagg gcaagggacg
    10801 agcctgacgt gaagtcaggc gaagtcctgc aggctgccgt ccagacaatt tctagccaag
    10861 caaaagctgg ctattctaac agccagcaaa aaggtacact taggacaacg tccaaagaac
    10921 gacggaacga gcaaacgttg atttgacggt gtttctgagg cctaaaaaat ctaaaagaag
    10981 gggggacaat tttgttgatt tctatacaag atttaagaag cattcaagaa cgatgtgaaa
    11041 taggagaatt agtacagagg ttagatgtca gtattgatag attaacggtt atctgggata
    11101 cagacactgg tcccctaaga cgaattttca aaaatctgaa acaggcaata agtacaagag
    11161 ttgactcatt tgaaatacat gataacgtgc gagatgatgt ctttacttta gctaaggatt
    11221 ttaatgagta tgattcaatc aatattatat ttttccaatt atccacttat ggaggtgaac
    11281 aattgattcg gattgatttc aatcctaaca ctttaaaaga atttgatgga atgaaagtat
    11341 ggaggtaatt aatgtacttt gccagattga attcattgac ggtacgtttg tctcgttttg
    11401 atttggcatt tgacattttc aacaggcctg aaatcgttaa tttgcaacat attaaaggtg
    11461 gtgttaccca taaggtcttc tatggtagag ggggcgaatt agagacgaaa tattggggtt
    11521 ctagcggtag taatgtacaa gttaggttat atgataagaa taaagaaatc attgctcata
    11581 agcacgaaga gaagctagat ttgggtgtaa atccgttttg gtggagacta gagttccaac
    11641 tcagaactaa agcgattggg gaggatatgg tgcaagatat tatgaatcga cttgataatt
    11701 tcggatttta taagctagaa catattcgag tggatcaaag agcctttaca attatctttc
    11761 taagcaatcc tgaactgtta tcattagctt ttccaaattt aaaatcagac agcatcaaaa
    11821 agaaaaaaac aagagtccgc aaactattga gagaagaaac gaatcaattt gcggaagaat
    11881 taaaagaagt attaatacag aatctcccta aattaaatac agaattacaa ctacttgtag
    11941 gtgagtttct gactttagaa aatcaataag gaggataact atggataata atttaattag
    12001 caacaaagaa ttaattgaaa tgggctatcg ccctcacact gcaaatgata tcatccatca
    12061 ggcaagagaa ttacttgtat cacgaggcta tacattttat aatcgcaaac gtttgatggt
    12121 tgttccaaaa agtgttgtaa atgagattct aggaacagag gtggcgtaat atggcaagtg
    12181 ttctttaccg aaagcgagga gatagtaatt tatggaccta tgaaattcgt aacgaaggaa
    12241 aaactgttgc tcataatagc ggttttaaaa caaaaaaact tgcagagtca gaagctgaac
    12301 cgattctgca agaacttcgt ttaggaaaaa gaatttctag agatatttct cttgccgatc
    12361 tatatcaaga atggcttgaa ctaaaaattt taccaagtag taggtcggaa gaaacaaaga
    12421 aaaaatatct tctccgtaaa aacacaattg aaagattatt tggaaataaa aaagtcactc
    12481 aaattcgtgc gagtgaatac caaagaatta tgaataagta tgggcaaaca gttggtagaa
    12541 attttcttgg tagattgaat acggggattc atcagagcat ccaaatggca attgctgaca
    12601 aagttctaat agatgatttt acacaacatg tcgagttgtt ttcatccaaa gaacaacaga
    12661 tgacagaaga gaaatattta catacagaaa aggactatct ggatttactt ttagcagtaa
    12721 agagaaaatt cgattaccaa cgttcaattg ttccttatat cgtctatttt ctattaaaaa
    12781 caggcatgag gtttggagag ttagtagcgt taacttggaa tgaggttgat tttgacagag
    12841 gattgttaaa aacatacagg aggtataata ctctctctca taagtttgtt ccaccaaaaa
    12901 ataaaacgtc tattcggatg gttccaatag acgaagagtg tatcaaaatt ttgcgccttt
    12961 tacaaacgga gcaagaaaga gcaaacatgg agttaggaat caaaaatcga tatcgaatga
    13021 tctttcaaca ttttggatat attcattcag ttccagatat tgcaagcgtc aataaagctt
    13081 tgagtgttct cttaaatgag ttggacattt atccaattat cacgacaaaa ggagcacgtc
    13141 acacctatgg aagctacctc tggcacaaag ggtttgacct tggagttatt gcaaaaattc
    13201 tagggcatag agatatttca atgttggtag aagtatatgg acacacttta gaagagaaaa
    13261 tttttgagga atttaatcaa atcagagata tctggaaaga ttgctcataa aaaaatgtgg
    13321 ggcaaacgat ggggcaaatg ctcttaagac aagcaaaaaa gccttggtta tcaaggcttt
    13381 tactgttgaa gtttgatgcc ccctacaggg ctcgaacctg tgacccatgg attaagagtc
    13441 cactgctcta ccaactgagc taaggaggct ggatgctgta ttggtaccga tgatccacag
    13501 tttgtat
//
