LOCUS       c00028_JAIQWS0..       13461 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIQWS010000035.1 Streptococcus salivarius strain DS85_40A
            NODE_35_length_14241_cov_47.122515, whole genome shotgun sequence.
ACCESSION   JAIQWS010000035
VERSION     JAIQWS010000035
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 20:14:09
            Original ID  :: JAIQWS010000035.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 780
            Orig. end    :: 14241
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13461
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[10780:12967](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12187)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..13461
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13461
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(280..642)
                     /locus_tag="ctg28_3"
                     /transl_table=11
                     /translation="MDYLEFLGRRLVWFVVSLVVVIVVKRPRLLNGLAIVSDEVIGKIN
                     YFIFLTIAWLVLVTYFILYLFTVVTFFLSWHSLTLNNVLEVILQTVLIIPTFYTLFVSH
                     NEVIKKVDEFLSAKKE"
     CDS             complement(660..1928)
                     /locus_tag="ctg28_4"
                     /transl_table=11
                     /translation="MQDIKNRDFTSLISNKKNKIHYTQRNKIASYFVSKKQNISLSFSE
                     EELIIFYHLLRFGYFDKEIIDLVYTAVTRKSKTPNSWFYRLVGKVNHPISACSDARSGK
                     RKIYYLNKGFSTWLLTMINGIDKIRLLTTTTEYDRSVYSIVSNNLLGGKPQTVNIHDLE
                     TRRLVAKILNKLFLKNQDKSVYDLNIQVVFPISRVNLLMVPDAVVFVNDNPFFIEYDRA
                     TERQTILLSKIFGYAEEPAFENSSLFFVFENSRKDNTQVSKRLMNFLEYVNEVEVEGVT
                     GHDMLKRKNISLFSQTTTNASDVIVEIIQEKMFSNHKDWCDCEAYDFSELQKIDYLVKE
                     ISEPLYDDKFQFSAVVETDSWELKEYPMIPMAYIKSDLIPHLTSLYEEFSIEYEHMIIV
                     FPKEVLPEKINLPFDNYFLTVYR"
     CDS             2469..2777
                     /locus_tag="ctg28_5"
                     /transl_table=11
                     /translation="MAGKNKKTESDFIKEIEAYEQQKKEAMEQLKAYQKSQTDKLGQIY
                     FELKKLENPDLSIDDLVVETHNKVKEVKKKIKRRKAEEKARKDAEKTNKETYNDSQK"
     CDS             complement(2817..5855)
                     /locus_tag="ctg28_6"
                     /transl_table=11
                     /translation="MRKILKLFFNRYYTNGKRTIDILLYCWRKYIDWVYHISFGLFAFN
                     IIMFIFRWRLPNWVFISLFIFLFVNMALVLYIGVWHSNVTSRQIFVLFEKYDTLKRAER
                     KKIIGKYAIRAALAAVLISSGLYVLTINNFILSLINRMYDVADNYLKYMPWSIPNGSQT
                     GIVLSYHTLKPIIGADWFNSLLLLTPIGVIGLIFYNSYATGIAEKTYEKLVEQWLGGRY
                     FQDSVLSNIVHNQDEKGQANLVMGLNSKTGEQVILHANERTYHTIIFGLIGTGKSATIL
                     IPAMLQDMENMKYYLLSYRKYLTKVDEELEEEFFNTEFERKKKRRELLEQWYNNGYAAE
                     LTNGIYMTEPSGSMYGTIVKYAHKMGFPDEMIWTLDPTNPGTGAINILDGDTTQVKGAV
                     RDLFKRFSDPSGTGSSFFLNQEGQLTDNIITVIKEVALIPDAPINYMLKGKSPTLTEFS
                     NMLRSSDWIEAYIAVFEQLLNRKKRLFEETLKKHEEFLEQEKEKWLEESEYNREHEQLF
                     DTILRPENVHEAINAFNDERNKLENLQSSYDYFINAHQLNSYTEEYYYTFDANVSGLKA
                     VIDDLSSSPEIRRVFFSQSTKDLDIVLKTGGMILVNSAKGVLGKEKSRMVAQMVTLVMQ
                     NAAQRRLPDKSPFFAFYEDEKNGYLMPGNDSNFLDESRKFHVPVMHAYQHDEQIRDSIG
                     ESGADAIKMSYRNAFTFQQTSTKVVEFINLRSGGKHYALKETKRAANDDLLAGNQGNSS
                     ATSEEVVEEDNFTARDANNLEKFQVGGVIVSDDEVSNMIYLTTSPHFEMDISKDSFVSH
                     TPFNKVYGLGEEEPEIAKAYKLWRAEVVEYYAQKESESHLYESDFTDEEWQAIMDVKVP
                     NVDSNVNDTVGKKDDSPSVKRTILVNESITEHRESTSISEEVTEDIEQKEEINNSEIPP
                     VVEEKQTVNSKNDIGELKDKEITQRVILAPSSTPETVDTQNIQAPNQEFELPQELSRVA
                     REKATKTLESNVEQMDIDEEEGF"
     CDS             complement(5867..6355)
                     /locus_tag="ctg28_7"
                     /transl_table=11
                     /translation="MNHHNINAIVYYLIVFIRYVLPITLVFIGIGRWSYAKSINNPEKQ
                     IMGVNFALKSILFLYIVTFIPIFIIYGLAMISKGGTHSGDFSMISFVEVFTLIEILAVG
                     ILPAYGFIQGYIYHYQWLITEGKKTTSLPRRNLFIRLGVISPIAIVVFMEFLKRMFAY"
     CDS             complement(6430..7761)
                     /locus_tag="ctg28_8"
                     /transl_table=11
                     /translation="MKALKLIREDGYENVHYASLGEQKFKTLVVADRKDEQEQWFEQPE
                     IECVPEEVSDIIRNYTLPYIDLGNTEDEYLLEQATNKVVSVVVENVLETQPFIPRNRNG
                     RPIGEGVAFCDMLVGRVQNGELAGTTVYIKQTESGFRQPKDFFKMVGRIFPCKLTEIHI
                     QTIDNYKLTINNPSNYVVEGSIELAEWLTNYQLLQQIEKSKDNSSRNRDRKNILERTHE
                     GIVSAVINNGSNAGIMVMTKKLQTVFIPKHRVSYECDSSFVNLDEVVSVFDRVEFKITG
                     ANTQKPSPNQRERHIIHDYIRIEGDMKVLEEAPQDALIEMIDDKKVIGRLFKVRFISFD
                     PQSLHTVELVDFPGIKIKMKDSGSLNRVPFKQGDEISVVILDAHYRWVDANSRGRRVAK
                     KTEEVSSNSQNTEEKKCLFRIKSRFNSFYPNRVNSKILSTFFTS"
     CDS             complement(8458..10026)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 148.7; E-value:
                     4.1e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg28_9"
                     /transl_table=11
                     /translation="MKKYILQFKFKNLLHLFLIACNSAFLVGASVTLAFMTNQLVAANF
                     KSFLIWLGIEILLYLLYLVFTYIITIHQAKLIQEMSLKIRSDYIKNITNSSFHTFQSKT
                     IGDHLSILNNDIQIIENSGFSNLYSLFSTLFTTLFSIIALLSYDIRIVVLTILLTICLT
                     YLPKPFATKMQHFMSLFSTANEELISGLNDQLSGYKTLYYSNKKPTLLIQNTKIIRNYI
                     TQKVNFTQNSTRIETIMSAFSIMAQMSILFLTGLLITLGQVSIGSISSVGQISGNIFNS
                     LTTLNQLQVSIHSVKPLFLKFEVSSKHTEKRTVNNIENIDISDLEYNFGNKTVFSKLNL
                     NLVKNKKYAIIGESGSGKSTLINIILGNLQNYTGHVKYNNLELKEIDENSIVSQVAYIS
                     NSTHIYNDTLENNLTLWSQDITQNEIKKALKNVNLLDLQGRLKEKVSNDLLSEGQKQRI
                     GIARALLKGSKIIIMDEATANLDKTNADFIENNLLKNPDITYITVTHHLSSEREKYFDQ
                     IIKLA"
     CDS             complement(10001..12187)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_10"
                     /sec_met_domain="LANC_like (E-value: 3.3e-10, bitscore:
                     28.7, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 8.5e-17, bitscore: 50.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTMIFPTNLSPDNLIINSNFTYVFSTNKSIPYQGWKIHISATL
                     DNYQIILDSVTTICLTNDTPFKFINSIEKLFFIFSKKTSQTEIGKFITIYPENDQTFLY
                     LLDVLYQELKYESGIQIMTDQNYKQSQVIFYRYGLMNASVKNGQRPCLFDNNGVAYPDL
                     PGAYYSCPEFVTEYFPEKTNTSTILNERYDMKSILYQTGAGNIYIAIDITNSQKVIIKE
                     ARKYVYATRDITSIELLKNEAKIIKKLSGSVTPNYIDDFYLEGNYYLVEEFIEGKTLNA
                     LKTDFNLLLKRTPSEITTFNNKLQKIISKLFKSLEYIHNHGVIVDDISCSNIILTSENK
                     VYFIDFETAYLKNEKPLIATTNSCYPKTIYEKFEHKDIVKLWYCIINLLTNASSLLKFD
                     QTGTATLKLFTKMCLEMNFPSQLLNKFMKDFKLERNNRMFFINFIKLGMDLEKLIYKRD
                     QLLDTLVTSSTIFIEGKSWCEKVDNYLAINQLGLTPSDKLTVKDIQGSDLDSQLARILL
                     DESQENLSDDMLSENFFNDLEYKEKYRLLTILNSKLKNPNLFRKLVKSIISNNIRYEKN
                     VPYLIIEDYLSPYLVDGNSGLIIELIKFSISEQTTEYDDFIKKLARGVEHPYAKSTSLY
                     NGLAGLGLANAWLYRYFDKMYYLQTSIDIVNHICDYSIEKNGKFILIDPIRDEIKYSYS
                     HGMLGQFYFFETLISLISKVQNKDKNYEKIHLTI"
     CDS             complement(12282..13154)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_11"
                     /sec_met_domain="TIGR01716 (E-value: 4.8e-39, bitscore:
                     123.7, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIETTEMGALFKKFRLSKKLALKDVAGDYLSISFLSKFERGESEI
                     SLSRFLLLLENLDVSIEEFYGILSKEKTTYTELLLERVSKAYYQNNILALKKYLKEENK
                     KYHDSNKKLFLYNTIMIESFLSTITEEDVDEDKIKIITDYLFDIEQWGKRELIILGNSM
                     PAISSETLNVLVKEVIYRTTLFGNNESNLKIRIDLLINATSEFIERNQLDLAKSYLDII
                     SDIGIPELFLYEKLEYNILLGAFWIKSGKVEIGKKLIENCLSILKTLGANNLLVSHEAY
                     YEELLNSTI"
ORIGIN
        1 tcactacaac taccgtcaaa atagataacg tcacaaggat agcatagcta atataccaac
       61 ccttgtaaag aggattatcc tttaacttgg ggaatgcatc acaaagggtt ttccaagcag
      121 attcaatttt tattttcatt aattaccgtt acctttcaat cttttttatc tttaaaacaa
      181 caccagatac ttacaacaaa ttcaaactat catgtgactt tcttacatat ttttaaatag
      241 ttgagagaat gattatatgt tgcagttgct gcgcgtgact tattcttttt tcgctgataa
      301 gaattcatca accttcttga taacctcgtt atgtgaaaca aataacgtat agaatgttgg
      361 tatgattaat acggtttgca aaatcacttc cagcacatta ttcagggtta gcgaatgcca
      421 tgataggaaa aaagtaacta ccgtaaacaa gtacaaaata aaatatgtga caagaactag
      481 ccaagcaatc gttaagaaaa taaagtagtt gattttaccg ataacttcat cacttactat
      541 agccaatcca ttcaaaagtc gtggtctttt tactacgatt acaactacaa gcgaaactac
      601 gaaccaaact aatcttcttc ctaagaattc caaataatcc atttactaac acctattatc
      661 tatctataaa cagtcaagaa ataattatca aaagggagat taattttttc tggtagaact
      721 tcttttggga atacaatgat catatgttca tactctattg agaattcttc atatagacta
      781 gttaaatgtg gaatcaagtc acttttgata tatgccatag gtatcatagg gtactctttc
      841 aattcccatg agtcagtttc aacaacagct gaaaactgga atttatcatc atataaaggt
      901 tctgatatct ccttaacgag ataatctatt ttctgcagtt cagaaaaatc ataagcctcg
      961 caatcacacc aatctttatg atttgaaaac atcttttctt gaatgatttc gacaataacg
     1021 tcagaagcat ttgttgttgt ttgactgaat aaagaaatat ttttacgctt taacatgtca
     1081 tgtccggtca caccttcaac ctcaacctca tttacatatt ccaaaaagtt cattaaacgt
     1141 ttagatactt gcgtattatc tttacggcta ttctcgaaaa cgaaaaataa actagaattt
     1201 tcaaatgctg gttcttctgc gtaaccaaat attttagaaa gtagaattgt ttgacgttct
     1261 gttgcacggt catactcaat aaaaaaaggg ttatcgttca caaatacaac agcatcagga
     1321 accatcaaaa gattaacccg actaatagga aatacgactt gtatgtttag gtcatagaca
     1381 gacttgtctt ggttttttaa aaaaagcttg tttaagattt tagcaactaa acgtctggtc
     1441 tctagatcat gaatatttac ggtttgaggt ttccctccta gaagattatt actgacaatg
     1501 ctatatactg acctatcata ttctgtcgtt gttgttagca accgtatttt atcaatcccg
     1561 ttaatcatag taagcaacca ggtactaaaa cctttgttca gataatatat ttttctctta
     1621 ccgcttctag catccgaaca tgctgaaata ggatgattaa cctttccaac aagacgataa
     1681 aaccatgaat taggggtttt ggatttacga gttactgcag tataaacgag atctatgatt
     1741 tccttatcaa aataaccaaa ccttagtaaa tgataaaaga tgataagctc ctcttctgaa
     1801 aacgatagtg agatattttg cttttttgaa acaaaataag aagctatttt atttctctga
     1861 gtgtaatgaa ttttattttt tttatttgaa ataagtgagg taaaatctct attttttata
     1921 tcttgcattt tgtagtccta aaatagtcaa tcaatagggt atatagtctg gtcttttttc
     1981 gaagagtgca gttaatattt taaaagtcgt gctatgcctt tactattgac ccacacaggc
     2041 attcttttgt acccgtaaaa tgatgattga tactttcatc tcctctcatt cataacgtcg
     2101 tagtttattt ttataacgct aatccctaaa aaacatgggt tattctagct aaatagtagc
     2161 cactatttac tcatttatga tttacgagtt tctaatatta gtcgtcaacc ctataaatac
     2221 agtaaactct tagacttttg ttctctctgt actttcattc ataaaatctg gttattacat
     2281 aacactcgta acaaccggtt ttatggggtt ttaagcactt aacaactact attaggattc
     2341 atttataata ggtcgctata gtgttcagta taccctagaa tagattattt tcaagggagt
     2401 gacatgggtt gacttttaat attcttgctc tatactatta gatataatta ataattaagg
     2461 ggcaaattat ggcaggaaaa aacaaaaaaa ctgaatcaga ttttattaag gaaattgagg
     2521 catacgaaca acaaaaaaaa gaggctatgg aacagcttaa ggcttatcaa aaatcacaaa
     2581 cagataaact aggccaaatc tatttcgaat tgaaaaaact agaaaatcca gatttatcta
     2641 ttgatgattt agttgttgaa acacataata aggtcaaaga ggtaaagaag aaaattaagc
     2701 gaagaaaagc agaagaaaaa gcaagaaagg atgctgagaa gactaataaa gaaacgtata
     2761 atgactctca aaaatagaac aaaagcaacg gaaatttccg ttgcttttta tgttatctaa
     2821 aacccttctt cttcatcaat atccatttgt tctacattac tttctaaagt tttagttgct
     2881 ttctcacgag ctacacgaga cagctcttga ggtaattcaa actcttgatt aggagcttga
     2941 atattttgag tatcaactgt ttcgggtgta gatgatggag ctaggatcac tctttgagtt
     3001 atttctttat ccttcaactc accaatatca tttttgctat ttacagtttg tttttcttca
     3061 acaactggtg gaatttctga gttattgatt tcctcttttt gctcaatatc ctctgttacc
     3121 tcttcactaa ttgaagtgct ttctctatgt tctgttatac tctcgttgac taatattgtt
     3181 cttttaactg atggggaatc atctttttta ccaactgtat catttacatt actatcaaca
     3241 tttggcacct taacatccat gattgcttgc cattcttcgt cagtaaaatc actttcatag
     3301 aggtggcttt cagactcttt ttgagcataa tattctacca cttctgctct ccacaacttg
     3361 tatgcttttg caatttccgg ttcttcctct ccgagcccat aaaccttatt gaaaggtgta
     3421 tgtgagacaa aagagtcctt tgaaatatcc atttcaaaat gcggagatgt tgtcaaataa
     3481 atcatatttg agacttcatc atcactgacg ataacaccac caacttggaa tttctctagg
     3541 ttatttgcat ctctagcagt gaagttatct tcttctacta cttcctctga agtcgcactg
     3601 gagttacctt gattccctgc taaaaggtca tcgtttgctg cacgtttggt ttctttaaga
     3661 gcgtaatgtt tccctcctga acgaagatta ataaactcta caacctttgt tgaggtttgt
     3721 tggaaggtaa aggcattacg ataagacatc ttgattgcat cagccccaga ttcgcctata
     3781 gaatccctaa tttgttcgtc atgttggtaa gcatgcataa ctggaacatg gaacttacga
     3841 gactcatcta ggaagttact atcattacct ggcatcaagt aaccattctt ttcatcttca
     3901 taaaaagcaa agaaaggaga cttatctgga agacgtcttt gagcagcatt ttgcataacc
     3961 aatgttacca tctgtgctac cattcgagac ttttctttac caagaacacc tttagcagaa
     4021 ttgaccaaaa tcattccacc tgtttttaaa acaatatcta aatctttggt actttgagag
     4081 aaaaatacac gacgaatttc tggtgaagat gataggtcat caataactgc ttttagacca
     4141 gacacgttag catcaaaggt ataataatat tcctctgtgt acgaatttaa ttgatgagca
     4201 ttgatgaaat aatcataaga actttggagg ttttcaagtt tatttctttc atcattaaag
     4261 gcgtttatag cttcatgaac attctctggt ctaaggatag tatcaaagag ttgttcgtgt
     4321 tcacgattgt actctgattc ctctaaccac ttttcttttt cctgctctaa gaactcttca
     4381 tgctttttca acgtttcttc aaaaagcctt ttctttcgat tcagtaattg ttcaaaaacg
     4441 gcaatatagg cttcaatcca atcgctagaa cgtaacatat ttgagaattc agttagtgtt
     4501 ggagacttac cttttaacat ataatttatt ggggcatctg gtatcaacgc aacctcttta
     4561 atgaccgtaa tgatattatc agtaagttgt ccttcttggt taagaaagaa agaagaacca
     4621 gtcccacttg gatcactaaa tcgtttaaat aagtctcgaa cagccccttt tacctgagta
     4681 gtatctccat ccaaaatatt aattgcacca gttcctgggt tagtaggatc tagagtccaa
     4741 atcatttcat cagggaagcc cattttatgt gcgtacttaa caattgtgcc atacatcgaa
     4801 cctgatggtt cagtcatata aataccattt gtaagctctg cagcataacc attgttatac
     4861 cactgttcca acaattcacg tctttttttc tttcgttcaa actctgtgtt aaagaattct
     4921 tcttccagtt cttcatctac tttcgtcaaa tacttacgat aggataatag atagtatttc
     4981 atattttcca tatcctgtag cattgctgga atcagaatcg ttgccgattt accagtacca
     5041 atcaaaccaa agataatagt atgataagtc ctctcattag catgtaaaat cacttgctct
     5101 ccagttttag agttaagccc cataaccaaa ttcgcttgac ctttttcatc ttgattatga
     5161 acaatattac ttaatacact gtcttgaaag taacgtcctc ctagccattg ctcaaccaat
     5221 ttctcgtagg ttttttcagc aattccagtt gcataactat tataaaaaat aaggccaatt
     5281 actcctatcg gagtcaacaa taataaactg ttgaaccagt ctgctcctat tataggtttg
     5341 agagtatgat aacttaaaac aatacctgtc tgacttccat ttggtattga ccagggcata
     5401 tatttgagat aattatctgc tacatcatac atacgattga tgagggataa gataaagtta
     5461 ttgattgtta gtacatataa tccagaagat ataagtactg ctgctaatgc tgctcttata
     5521 gcatacttac caataatttt ctttcgttct gctcgtttta aggtatcata tttttcaaat
     5581 aacacgaaaa tttgacgact tgtaacatta ctgtgccata caccaatgta taaaactaaa
     5641 gccatattaa cgaacaaaaa tataaataaa gatataaata cccaattagg caaacgccat
     5701 ctgaagataa acataataat attgaaagca aataatccaa aagatatatg atatacccaa
     5761 tcaatatatt ttcgccaaca atacagcaag atatctattg ttcgcttacc atttgtataa
     5821 taacgattaa aaaataattt caagatcttc cgcataaagc acctctctag taagcaaaca
     5881 ttcttttcaa gaattccata aatacaacaa tagcaatcgg acttattact ccaagtctaa
     5941 tgaatagatt tcgtcgaggt aagcttgttg ttttcttacc ttctgtaatc aaccattgat
     6001 agtgatatat gtatccttgt atgaaaccat atgcaggtaa tatcccaacc gctagaattt
     6061 ctattagggt aaagacttct acgaaactaa tcatagagaa atcaccacta tgtgtgcctc
     6121 cctttgatat cattgcgagt ccatagatga tgaaaatagg gataaatgta acgatatata
     6181 agaataaaat tgattttaag gcaaaattta ctcccatgat ttgtttctct ggattattga
     6241 tagatttagc ataactccac ctaccgatac cgatgaagac caaggtaata ggtaagacat
     6301 accgaataaa gactatcaga taatagacga tagcattgat attatgatga ttcatgttcc
     6361 ctccttgtta aatttttctg atccgaacgt aaacaaaaag ttcccatttc agagggaact
     6421 atatgcaact caactagtga aaaatgttga taagatttta ctgttcacac gatttggata
     6481 gaaactattg aaacgtgatt tgatacgaaa cagacatttt ttctcttccg tattctgtga
     6541 attactgctc acttcttcag tttttttagc cactcgacgc cccctgctat ttgcgtctac
     6601 ccagcgataa tgagcatcta gtatgacaac tgaaatttca tctccttgct taaaaggaac
     6661 ccgatttaaa gaacccgagt ccttcatttt aattttgatt cctggaaagt caaccaactc
     6721 tacagtatgt agactttgtg gatcaaaact gataaatcgc actttaaaca atcgtcctat
     6781 gactttctta tcatcaatca tctcaatcaa agcatcttga ggtgcttctt cgagaacttt
     6841 catatctccc tcgatacgaa tatagtcatg gataatgtga cgttctcttt gatttggact
     6901 tggtttttgg gtattggccc cagtaatttt aaattccacc ctatcaaaga ctgatactac
     6961 ttcgtctagg ttaacaaatg aagaatcaca ctcataactt accctatgtt ttggaatgaa
     7021 taccgtttgt aattttttgg tcattaccat gatacctgca ttgctaccat tgttaatcac
     7081 ggcagataca ataccttcat gcgtacgttc caagatgttt tttctatctc gattacgaga
     7141 agagttatct ttactctttt caatttgctg aagaagctgg taattagtta accactcagc
     7201 taactcaata ctaccttcaa caacatagtt tgatgggtta ttaatcgtta gtttataatt
     7261 gtcgatagtt tggatatgaa tttcagttaa tttgcaaggg aaaatacgcc caaccatttt
     7321 aaagaagtct tttggttggc ggaagccaga ttctgtttgt ttaatataaa ctgttgttcc
     7381 agcaagttct ccattctgaa cacgccctac taacatatcg cagaatgcga caccttcacc
     7441 gatagggcga ccatttctat ttctcggaat aaatggctgt gtttcaagta cattctctac
     7501 tacaactgat acaaccttat tagttgcttg ttctaacaaa tactcatctt cagtatttcc
     7561 gagatcaata tatgggagtg tatagtttcg aatgatatct gaaacttctt ctggaacaca
     7621 ttcaatttct ggttgctcaa accattgttc ttgttcatct ttcctatctg caacaaccaa
     7681 tgttttaaat ttttgctccc ctaaactagc ataatggacg ttctcataac cgtcctctct
     7741 tataagttta agtgctttca tatgtttctc ctttaatgtc ttttttgaca ttaaaagcat
     7801 aacaaaaaag gtcactacct gtaagatagt gacccccctt gacttttgtt aattcatagc
     7861 gataagaagc ccaacaccta agactacaat tggtgtaatt aaggcgaaaa ttgaaaagat
     7921 tttcttggcg ataccgatgg taacatataa gaaactcgct aatgttagta atagaaccaa
     7981 gatcataaac ataattctca ccctttcttc tggctctgtt tttaattatt attatataga
     8041 tttttgatat caatgcaagg ctagagagca acaaatgtaa agataagagg ttacaaaata
     8101 attttcagaa tcagtacaaa acggttggtt tactcttctt accctttcag tactccgtaa
     8161 ctgaggaaat acttagtttg ggtaaactga ccaaaatgtg aatattatct gaacaagctt
     8221 ttactttaag tttcttaaca cttttttata taattgacaa aagatttgag caatatttac
     8281 tctgtatttc ccatagatta ttttacacta cctctttgct taaatgatat aaatgagtat
     8341 aaacaaaaca aatctaaagg acatctatgt cacttagatt cgttattttg tatttaaatc
     8401 tttttccatt tttagatttc tgatgaggac ttggtcgcca aaagcttctg cacattatta
     8461 tgctaattta atgatttgat caaagtattt ttctctttct gaactaaggt gatgtgttac
     8521 ggtaatgtag gtaatatcag gattttttaa aagattattt tcaataaaat cagcattagt
     8581 cttatcaaga ttggctgtag cttcatccat aataataatt ttactgcctt ttaatagggc
     8641 tcttgcaata ccaattcttt gtttttggcc ttctgaaagt agatcattag ataccttttc
     8701 ctttaaacgc ccctgtaagt ccagtaaatt gacatttttc aaagcttttt ttatttcatt
     8761 ttgtgtaatg tcttgagacc acagagttaa attattttca agtgtgtcat tgtaaatatg
     8821 tgtggaatta ctaatatatg cgacttgaga aacaatggaa ttttcatcaa tttcttttaa
     8881 ctctaaattg ttgtatttta catgaccagt ataattctgg agatttccta agataatatt
     8941 tatcaatgtt gactttccac ttccagattc accgataata gcgtattttt tatttttaac
     9001 taagttgaga ttgagtttag agaagactgt cttattacca aaattgtatt ctaaatcgga
     9061 aatatcaata ttctcaatgt tatttactgt tcttttctca gtatgtttag aagaaacctc
     9121 aaattttaaa aataaaggtt taacagaatg aattgacact tgtagttgat taagtgttgt
     9181 taatgaatta aaaatattac ctgaaatttg tcctacagaa gatatagaac caattgaaac
     9241 ttgtcctaaa gtgataagta aacctgtcaa gaaaagaatt gacatttgtg ccataataga
     9301 aaatgcagac atgattgtct ctattctagt actgttttga gtaaagttta ctttttgtgt
     9361 gatatagttc ctaattattt ttgtgttctg aattaataga gtaggttttt tattcgaata
     9421 ataaagtgtt ttgtatcctg ataattggtc atttaatcca gatatgagct cttcgtttgc
     9481 agttgaaaat agcgacataa aatgttgcat ttttgtagca aatggtttag gaaggtatgt
     9541 aagacaaatt gttaatagta tagttaaaac tacaattcta atatcataac ttaaaagagc
     9601 aataatagaa aagagagtgg taaataatgt agaaaataga ctgtataaat ttgaaaagcc
     9661 actattttcg atgatttgaa tatcattatt taaaatggag agatgatctc cgatagtttt
     9721 gctttggaaa gtatggaaag aagaattagt tatatttttg atataatcgg aacgaatttt
     9781 tagagacatt tcttgtatta acttagcttg atgaatagta atgatataag taaatacaag
     9841 atagagaagg taaagtaata tttcaattcc caaccaaata aggaagcttt taaaattagc
     9901 tgcgactaat tgattggtca taaatgctaa ggtaacagaa gcacctacaa gaaatgcaga
     9961 attacaagca ataagaaata gatgcagtaa atttttaaat ttaaattgta agatgtattt
    10021 tttcataatt tttgtcctta ttttgtacct tacttatcaa agagataaga gtttcaaaaa
    10081 aatagaattg gcctaacatg ccatgagaat agctatactt tatttcatca cgtattggat
    10141 caattaatat aaatttacca tttttttcta ttgagtaatc acaaatgtga ttaacgatat
    10201 caatactagt ctgtaaataa tacattttat caaaatagcg atataaccag gcatttgcaa
    10261 gcccaagccc tgctaatcca ttatagagtg atgtactttt ggcataggga tgttctactc
    10321 ctctagctag ctttttaata aaatcatcat attctgtagt ttgttcagaa atactaaatt
    10381 ttattaattc aataattaaa cctgagtttc catctactag atatggagaa agatagtctt
    10441 caatgattag ataaggaaca tttttttcgt atctgatgtt attagaaata atagatttta
    10501 ctagcttcct aaataaatta ggatttttta gttttgagtt taaaatggtt agtagacgat
    10561 atttttcttt gtattccaga tcattaaaaa agttttcaga taacatgtcg tcagataaat
    10621 tttcttgtga ttcatctagt aaaattcttg ctaactgaga atctaaatca cttccttgaa
    10681 tatcttttac tgttaattta tcagatggag taagtcctaa ttgatttatt gctagatagt
    10741 tatctacttt ttcacaccaa gatttacctt ctataaaaat tgtagaacta gttactagag
    10801 tatctaacag ttgatctcgt ttatatatga gtttttccaa atccattcct agtttgataa
    10861 agttaataaa aaacattcta ttgttccttt ctaacttaaa gtctttcata aatttattta
    10921 atagttgtga agggaagttc atctctaaac acatctttgt aaatagcttt aaggtcgctg
    10981 ttccagtttg atcaaatttt aaaagtgaac ttgcattggt taatagattg atgatacagt
    11041 accataattt gactatatct ttatgttcaa atttttcata tattgttttt ggatagcagc
    11101 tatttgttgt tgctatcaat ggtttttcat tttttaaata tgctgtttca aagtcaataa
    11161 aataaacttt gttttctgat gttaatatga tattactaca ggagatatcg tcaacaataa
    11221 caccatgatt atggatatat tctaatgatt taaatagctt tgaaataatt ttttggagtt
    11281 tattattgaa agttgtaatt tctgaaggag ttcgttttag gagtaaatta aagtctgttt
    11341 ttaaagcgtt aagtgttttt ccttcaataa attcctcaac gaggtaatag ttaccttcta
    11401 aataaaaatc atcaatgtaa ttaggagtta ctgaacctga taatttttta attattttag
    11461 cttcattttt tagtaattct atagaagtaa tatccctagt agcatagaca tattttcgag
    11521 cttcttttat aatcactttt tgggaattag taatatcgat tgcgatatag atatttcctg
    11581 caccagtttg ataaaggatg gatttcatat cgtatctctc atttaggata gtagaggtat
    11641 tagttttttc aggaaagtat tctgttacaa attcagggca agaatagtat gcacccggta
    11701 gatctggata tgcaacacca ttattatcaa aaagacaggg tctttggccg ttttttacag
    11761 atgcattcat gagtccatac ctataaaata taacctgtga ctgtttataa ttttggtctg
    11821 tcattatttg gatgccagat tcatatttta attcttgata taggacatcg agtagataga
    11881 gaaaggtttg atcgttttca gggtagatag taataaactt tccaatctca gtttgagatg
    11941 tcttttttga aaagataaaa aataattttt ctatagagtt tataaattta aatggggtat
    12001 cgttcgttaa acagatagta gttacagaat ctaatattat ttgataatta tctaatgttg
    12061 ctgaaatatg tatcttccag ccttggtatg ggatagattt attagttgaa aatacatagg
    12121 taaagttaga gttaataatt aagttatctg gggatagatt agttggaaaa atcatggtat
    12181 caatcataaa tattctcctt aaaaaaagct agaactataa aaagataata tctttttata
    12241 gttctagctt acaccatttt aaacatcaaa gttagatatt gttatatagt ggaatttagt
    12301 agttcttcat agtaggcttc gtgagatacg agtagattat ttgctcctaa agttttgagg
    12361 attgaaaggc agttctcaat aagttttttt ccaatttcaa ctttacctga tttaatccag
    12421 aaagctccta aaagtatatt atactcaagt ttttcgtata aaaagagttc tggaatacct
    12481 atatctgaaa ttatatctaa atacgacttt gctaaatcta gttgatttct ttcaataaat
    12541 tcagatgttg catttatcag taaatcaatc ctaattttta aatttgattc attatttcca
    12601 aaaagagttg ttctgtaaat gacttctttg acaagtacat tgagagtttc tgaagaaata
    12661 gctggcatac tatttcctag tattatcaac tccctcttac cccattgttc aatatcaaaa
    12721 agataatccg tgataatttt tattttatcc tcatctacgt cttcctctgt aattgtagat
    12781 aaaaaggatt caatcatgat tgtattatac aggaataatt ttttattgct atcatgatat
    12841 tttttattct cttcttttag gtattttttt aaagcaagta tattattttg ataatacgcc
    12901 ttactaacac gttctaacag tagttctgta taagtcgttt tttcttttga gagaatacca
    12961 tagaattctt ctatactaac atctagattt tctagtagta ataagaaccg agataaagaa
    13021 atttctgatt ctccacgctc aaattttgac aagaaagata tagataagta gtcaccagca
    13081 acgtctttta aagctaattt ttttgataag cgaaactttt tgaatagtgc gcccatttct
    13141 gttgtttcaa tcatagtact tctttcaata ggtaaaattt taatagatta tatcaaaaaa
    13201 aaaaaaaaag taaaaagacc tatgtttagc gaacatagcc ttcttactgt taagatacta
    13261 cgataggaca atagagagtg ataatcagtc caccttgtgt ggtaattctt tcttaaggaa
    13321 gtttattaag ttgttgtaca ttcatatttt ttctccttta tactgcgata gggcaataga
    13381 gggtgataat cggtctacct tgtgtagtga ttctttcttg aggaagtttg ttaagttgtt
    13441 gtacattcat attttttctc c
//
