LOCUS       c00016_JAIZBX0..       18003 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIZBX010000023.1 Streptococcus thermophilus strain ST1 23, whole
            genome shotgun sequence.
ACCESSION   JAIZBX010000023
VERSION     JAIZBX010000023
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:44:25
            Original ID  :: JAIZBX010000023.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 18003
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18003
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4777:8003]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4778..8003
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..18003
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18003
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(2..157)
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="VGNEKLTSREDRIGPFFMYVQCDEDTLLKVDKVSKTEAQPFDVFD
                     QLISRFK"
     CDS             complement(194..913)
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(929..1159)
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="MKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAAFASLLQEALT
                     QAVDGPVLIDVPIDYRDNIKLGETILPDEFY"
     CDS             complement(1160..2605)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 436.3;
                     E-value: 2.9e-132)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_4"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQE"
     CDS             complement(2859..4031)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_5"
                     /transl_table=11
                     /translation="LKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             complement(4038..4781)
                     /locus_tag="ctg16_6"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             complement(4778..5602)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_7"
                     /sec_met_domain="PF04055 (E-value: 1.9e-14, bitscore: 44.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.5e-12, bitscore:
                     38.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4.4e-10, bitscore: 30.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVDFTGGEPLLLQGLSEIIEEVLKEGMCTTIFTNAVYIPEDFKI
                     LIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGVPVTVNVVLNNKNI
                     SGVKYFLELFDRLDVKYAFDRFLPFERNNRLSISDEEFNNAILCIPNIQANCNNISEST
                     FESFYCGAGNSYVFINSSGDVGFCPTLSSTKFCGGNINEKTLNDIWINSKFFNHIRNVR
                     CKYYNECPANYVCQGGCRSRAQFFGGSIGSPDIQECKLAYNLTGIKPKSMSL"
     CDS             complement(6077..6226)
                     /locus_tag="ctg16_8"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGRC
                     PPSV"
     CDS             complement(6286..7086)
                     /locus_tag="ctg16_9"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             complement(7146..8003)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_10"
                     /sec_met_domain="TIGR01716 (E-value: 7.1e-47, bitscore:
                     150.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNTINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCITAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             complement(8526..10358)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 550.5; E-value:
                     8.6e-167)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDTIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             complement(10814..11539)
                     /NRPS_PKS="Domain: PKS_KR (13-129). E-value: 1.1e-11.
                     Score: 36.7. Matches aSDomain:
                     nrpspksdomains_ctg16_12_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     196.3; E-value: 1e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_12"
                     /sec_met_domain="adh_short (E-value: 1.1e-35, bitscore:
                     113.7, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTPIGRGGFRMSKVAIVTGAGQGIGFAIAKRLVEDGFRVGVLDYN
                     AETAEKAVAELSADKAFAVVADVSKQAEVAAAFQKVVDHFGDLNVVINNAGVAPTTPLD
                     TITEEQFQRTFNINVGGVIWGAQAAQAQFKALGHGGKIINATSQAGVVGNPNLTVYGGT
                     KFVVRGITQTLARDLADSGITVNAYAPGIVKTPMMFDISHEVGKMLVKMMSRVCKLLLK
                     ILPSNVCQNLKMLQQPLAS"
     aSDomain        complement(11153..11500)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg16_12_PKS_KR.1"
                     /evalue="1.10E-11"
                     /label="ctg16_12_PKS_KR.1"
                     /locus_tag="ctg16_12"
                     /protein_end="129"
                     /protein_start="13"
                     /score="36.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAIAKRLVEDGFRVGVLDYNAETAEKAVAELSA
                     DKAFAVVADVSKQAEVAAAFQKVVDHFGDLNVVINNAGVAPTTPLDTITEEQFQRTFNI
                     NVGGVIWGAQAA"
     aSModule        11153..11500
                     /domains="nrpspksdomains_ctg16_12_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg16_12"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(11432..11494)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg16_12_0001"
                     /evalue="9.70E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg16_12"
                     /protein_end="36"
                     /protein_start="15"
                     /score="11.8"
                     /tool="antismash"
                     /translation="IVTGAGQGIGFAIAKRLVEDG"
     CDS             complement(11720..12013)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 59.2;
                     E-value: 5.6e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_13"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDDSIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             complement(12015..12443)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             12814..13545
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MWHLDFVWGLKGIERYIAEHGYTFKDHDGGQYETRKDIGIRITEP
                     LSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHAYTELAIFDRLAVPGQVYETNEELKK
                     GLINAYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPASFYSDGNGDLAELADEFVAINN
                     EVVDYTHELGLTVWTHNCRGNYEIRSAAEGTYEDIAKKFLAEQHYDCFFLEWDSDTAGD
                     IKALEALKDSKAEVVFGLLSS"
     CDS             complement(13810..15153)
                     /locus_tag="ctg16_16"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
     CDS             complement(15254..16648)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 127.2; E-value: 1.8e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_17"
                     /transl_table=11
                     /translation="VALIKKREHSLRTILLSYVVSLTVLSVISSLLILYLFSLSFRFGV
                     VIPANQVESDLSAVRSDIETSKVFNPEILPDGTSYVFLTRDFKLKKSNMLVNLQEESLL
                     NYQFKNAHGEKYGYFQSFERSDGIVIVNYQLSPRYRNEWMNQHFPNADLMMIGSMFVSI
                     LIIFIILTFYYANKLSQQLKPILRVTEKISQQDLDFQTSQSTIKEFNQVLSGLDHMRIA
                     LRESLMENWKAEQDKQNQISALTHDLKTPLTVARGNAELLAMTSLDENQTELLEHFQKG
                     IAQVDAYVKELSELNKMSLKKTLTLEEVPVKEFVEDIYDQTLSLAQTKQINVVFDKKEI
                     AKESIGNWDKSLLNRAIMNIVSNAVEHTPSGSQLLLTARVEEDEFKFICLDSGPGFSLE
                     SLENATQLFYQEDKSRQSRNHSGLGLTIANDIIRLHYGSLSLANDNGTGGAKVTIILPL
                     LNTDDS"
     CDS             complement(16639..17298)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 180.3; E-value: 6.9e-55)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_18"
                     /transl_table=11
                     /translation="MARILVIDDQKDIVQLVVKALELQNHNVTGLTSVLDLDKNSLPRF
                     DLILLDIMMPDVDGLQFCHEIRNQVDCPILFITAKTQEADIVQGLSYGADDYICKPFGV
                     KELQARVAAHLRREHRERHHKLSLGEFQFDLSAQELYIENQLLDLTKSEYGICQFLAEN
                     KGQVFSKEQIYTHLYGYEDKGSPAAVAEHIKNIRAKLKEVGQNPIETVWGIGYKWH"
ORIGIN
        1 acttgaagcg actaataagt tgatcaaaga catcaaacgg ttgggcttcg gttttagaaa
       61 ctttatcaac tttaagaagc gtgtcttcat cacactgaac atacataaaa aaaggaccta
      121 tccggtcctc tctagatgtt agcttttcgt tacccactac agttgacaaa gagacagtat
      181 cttatttata tgcttattca gccttagtaa tatctttacg catttcatca acattgaatt
      241 tagcaaagag atattgacgg tcttgaactg ggaagcgttg atcgagttgg tcaactggtc
      301 caacttcaat aataccattc tcgataacaa aatccataac gtgaccaccg aatgtcaagt
      361 catctgaaat aaaatggaga tggtaaccag caacactcac accgtggaac atttcaggtg
      421 tccagatacc aacgattgta cctgaaatat catctacctc atactcaggt tggcgagtgg
      481 caacatcagc aaacttaatg tccgcatttg attttggaat catgcgcacg tgcatgtgtt
      541 taaaatgacc tttgattttg attgaacgga aaagattgac cccatcatag tatgattcaa
      601 tacgatcctc aagttcttta tcagtcattt cataacgttg acggaagata acttcagctt
      661 ggtgaggtac gactgctgca tagggaactt tttcatcagg agagacttct accacttcga
      721 ctttaccttc agagccttta gcttgatagg ctttaccgtc aagaacaatc aactcaccat
      781 cgatagaatc taatgttccg aggcccaagt ctccatgctc taacaactct ccaacagtta
      841 aagtacctcc ataaagccca gccatcaagg ctcccaaagt attatattga aataatttta
      901 tggcttcaga catgtctaca ccctcttttt agtaaaattc atctggcaaa atagtttcgc
      961 cgagtttaat gttatctcta tagtcaattg gaacatcaat aaggactggt ccatctacag
     1021 cctgagtcaa agcctcttga agcaagctag caaacgctgc tttacttgtt gcacgataac
     1081 ctttggctcc aaagctctca gcatatttta caaaatctac aggaccaaag tcaaccccag
     1141 atgaacgacc gtacttcatt tattcctgga attccaccat attgtaatga ccatcgttcc
     1201 agataatatg gacaattggc aatttcaaac gaactgctgt ttccaattct tgtgctgaga
     1261 agaggaaacc accatcacca gaaacagaaa tcacttttgt cttaggacga accaaagctg
     1321 cagagatagc ccatggaaga gcaacaccta gcgtttgcat cccatttgag aaaagcaaat
     1381 gacgtggttc atacgatttg aaataacgtg ccatccaaat atagtgacta ccaacatcaa
     1441 ccgtaacagt catatcatca tctgtttgtt cttgcaaaac ttcgattaaa tctagcggat
     1501 gcaccgtacc ttcatcaggc tgacggtcaa acttaacatc ctcaacaaca ttgtttttca
     1561 aacctttaag atattcaacc gaaccttcag gcaatttata accttgaata gcgggcaaaa
     1621 gcaagtttaa gctcgcttct acattaccaa tcaattcacg ttccggttgg aagtaagtgt
     1681 ccacctcggc cggctcaaca tcaataacga tgatacgtgc tgaaatttca gcattccagt
     1741 tacgtgcttc atattcgatt gggtcataac caatggcaat aactaagtcg gattttttaa
     1801 gcaacatgtc tccgggttgg ttacggaaaa gacctacacg accaaagaaa gtatcttctt
     1861 caaggtcacg tgacacgata ccggcacctt ggaaagtttc aacaactggc aatttaacat
     1921 gcttcaaaat ttggcgaata gagtaagtta cggcttctga tgaggcacca ttccccaaaa
     1981 gaaagactgg caacactgca tttttaatgg cttgtgctag atagttaata tcagaaacag
     2041 atgctgaacc aagttttgga tctgtcatag gcttaatagc cttaacactg accggagcat
     2101 ccgtcacgtc ttgaggaatt gaaatgaagc ttgcacctgg tttccctgac ttagcgtgac
     2161 gataggcatt agcaaccgtt tcagaaaggg tgttagcatc atgtacttca gcagcatatt
     2221 tggtaattgg ctcaagcata gcaacgttat tcattgattg gtgggcacgt ttcaagagat
     2281 ctgcacgctt aacctgacca ccaatagcaa gaacagggtc tccttcatcc gtcgctgtta
     2341 ccaaaccagt agccaaattg gagacacctg gaccagatgt taccaatact acacctggtt
     2401 tcccagtaat acgtccaaca ccttgagcca taaaagcagc attttgctca tgacgggcaa
     2461 caatcaattc aggtccctta tcttccaagg tatcaaaaac cctatcgatt tttgcgcctg
     2521 gaatcccaaa gacatactca acatcatggt tgatcaaact atcaaccact aaatctgcac
     2581 catacaattg cttttcttct gacatgaaca cagtccttct agccctaaaa tggtagagcc
     2641 aactttcctt tcaagtataa gtcacaaagt gtcaaagtct gctcgttttt tcacaaactt
     2701 tcatcaattc acaattctgt tatcattata gcacagtttt cagacaatct tgtgaaaaaa
     2761 ggcagactag gtgactaaaa aaagacaaac actcaaaata gcgtttgtct actttataaa
     2821 ttaactatct catttgcttg ttttctgatt tataaatatt acttatcaat gcttagtttt
     2881 ttgaggttta caaacacaca ataacacaga agaataaaca gagcaaaaac agcaagactt
     2941 ctgaaaacta aaacaagatg actacttaaa aaggcaaaac ttcctattac taaaacagca
     3001 atgcctgaaa atacagaatg taaggtctcc gagtaaatat atagtttctg taattctttc
     3061 atgttaagtg acaactgaaa ataattggtt tcgattatcc ccatcattgt ctgacctatc
     3121 gctagaaaaa cataactcat tagtactgta taaatgttcg aagatgtact aaataaaagt
     3181 agatatagaa cataaaatga aagacctaag gcgaaagctt tcatatgaga acttatttgt
     3241 ttcacgaagc taagaaggaa gctcattact aagaatgaaa ctgctaaaaa tgataaggaa
     3301 aaggaataca tagaatcact aataccgaga tactttgtta aataaacaac ttcataagta
     3361 tcataaacaa ctccaattga tcccacaata actccagata atagaactaa tgcaattttt
     3421 ttggatctca gaatgttaaa taatgtaatg tttaaatttt gtttttttct ttcttctttc
     3481 aaatttaaag tcgaaatatt tggtaaaaat aaaagactag tagctcccac tatcaaaaga
     3541 agagcataaa ctgcaaacaa taaaaagtga cttttattaa taaataaacc aacaaacaac
     3601 ggtgctaaaa aataagatac tgaaccaatg cttgtatacc tagcgttaaa cttaatcaat
     3661 gaatccttgt ctataataat tggtacacaa ctatataata aactggaaaa caatacattg
     3721 acaacctcaa ttatgaatac aactaatagg acaattatat ggtttaatcc aaaacctagt
     3781 aagaaaagta agattgcctt tgtaatttct aacagaataa gcaggtattt tctgctcagt
     3841 ttactatttg agatattaat cctatttgta actattgcag ctaaacactt taccacccaa
     3901 aaatacataa ctaattgcac agaaattcta gacaatagaa tgttgatcaa gatagtataa
     3961 ccatactctg agattaacga tgagaaacga ttaaaataaa tactcaatgc tgcatatttt
     4021 tttattttca atatttccta tatcctcctt aattttgatt taacaaattg aatcatttgg
     4081 taaaaaatgt gagcattatc acttccaacc atcggattgt actcaactat atcacaaaaa
     4141 tataccttat cagaacataa aattttggaa attattccaa gaaaatcgtt catttgaaat
     4201 cctccaataa taggatatga tactgaatca aaaacagatg gatccaaaac atcaatgtct
     4261 attgataagt aaatatcttt tgactcatca atataactat ctagcttttt caaaactcta
     4321 ctcttattta accaatactc ctccattgag aggatgatta ttttattatc aaatgaacta
     4381 ggaaactcaa aattcctttc cccaatgata attatttttt caaaaatatc ggttaaaaaa
     4441 cttaaaaaat tccaattttt tacaacactt tcaaagtctt tgaagtaatc taaatgagca
     4501 tctaaaacaa ttaaatatgc tccctctcga acagtggcct ttgctaatag ataagtaact
     4561 gaatgatctc ctcctaaagc aatctgaact ttagattcag caatagttcg acttagactt
     4621 tctaaatcaa tagaaaataa atcttgatta cctaaattaa ttgtaattat atcagaatct
     4681 ttcctatcat ataacatcgc ttcttgataa tattttgtgg gagcaaatct cgctcctgga
     4741 attctacttc caccatcata aataatagat aatattttca taaactcatt gactttggct
     4801 taatcccagt taaattatat gctaacttgc actcctgtat atcgggactc ccaatagaac
     4861 ctccgaaaaa ctgagctcga cttctacacc caccttgaca aacataattt gcagggcatt
     4921 cattataata cttacatcgt acatttcgaa tatgattgaa gaacttcgaa ttaatccaaa
     4981 tatcatttaa agtcttttca ttaatgttac ctccacaaaa tttagtggag gataatgtcg
     5041 gacaaaatcc aacatcacct gacgaattta taaacacata agaattgcca gcaccacaat
     5101 aaaatgattc aaatgtggat tcggatatat tattacaatt tgcttgaata ttgggaatac
     5161 acaaaatagc attattgaat tcttcatcac taattgatag tcgattattc ctttcaaaag
     5221 gtaaaaacct atcaaaagca tatttcacat ctaatcgatc aaacaactcc aaaaaatact
     5281 tcactccact aatattcttg ttattcaaaa caacattaac agtaacaggt actcctaaac
     5341 tcctaaaata ttcaatattc ttaattgttc tcttaaatgt acctcttcct ctaattgaat
     5401 catgtattgt ttcattccaa ccatctaaac taacttttag tcttatacca tcatatcttt
     5461 gaatcaatat tttaaaatct tcaggaatat atacagcatt tgtaaaaatt gttgtacaca
     5521 ttccctcttt taatacttcc tcgataattt cacttaatcc ctgtaataat aatggttcgc
     5581 ctccagtgaa atcaacatcc attactccta gctgcttagc ttcatatact atacttgaaa
     5641 ttttctttct atcgagctcc tttgaataat caggtaaata acaatgcata catcttaggt
     5701 tacatttgtt cgtgacctca atctgtatca cttttaatgg tattttcgtt gaaaattcaa
     5761 caattttagt gttggtctta gagagtgata tttcattgtt atttagaaaa tctataacat
     5821 tttttattac ctgactcttt gaatcagaaa actttttcaa tgaaaattgg tacataaatt
     5881 ttaaagctaa aaatgtagct aaatttaatg aaaatagttt attattccta ttattcctga
     5941 gtattccttg cttattgtac caattaaaaa aatcgagtaa acattgctcg tcatattaat
     6001 tccctgcaat cttccaaaaa tattaatata aaaaccaaag gattagaaat agactctaat
     6061 cctacaatca gttctattag acagacggtg ggcaacgacc tttgagtcca tcaatcaact
     6121 ctgtagcaac agaaggttta atttccataa tgtcaataga tagaccgcta gaaacaactt
     6181 cttcttctgc taattcaatt tgtgcaatag catcactaac ttgcatcgta atatcctcca
     6241 ttatttattt aagaatcaat aagtacccat aacaaatcat agaaatcatt ctttatctat
     6301 aaaatttaac tgaaaatgct ttgaaattgt cttattaaac tgatttgcaa taataaagta
     6361 tatgttatct gttcgtatat atgatatttt tttataaaca tcttcacaaa ctctcttgta
     6421 aagattccaa aattgatttg cttgtgaact tgtataagat aagggtatac ttccccatct
     6481 aaaatctaaa taatatatat accatttttc atattcttta aactctgtag tgccatcggc
     6541 agtctttgtt cgataatact ctgataaagt gtttttaaaa ttgttttgat actcaatctc
     6601 atatttcagc ctttcctctg aaacatgcaa agacggacta aaaactggca ccccagtttt
     6661 aatatatcgt aaaactacat cctctatatc cttgtacctc tgcccctcac caaggttcag
     6721 ttgaaatgtc ggacaaggag taaaagaaac aatatagaag ttctgaattt tcttaatatg
     6781 aaaaggatat aattcacaag ttaatggctt gttcaagcct aaatcattta tcgtacaacc
     6841 caattcagaa tgaaaccagc actttttacc acaactcaac aatgaaacac tatcatcact
     6901 aacaataaaa tctttaagat acgtgcgttt tagaaaactt gctgtctttg catcaagtaa
     6961 taaagaatta ttcacatgac aacaagatcc tctacacttt tcacaattat aagagataat
     7021 atcatctaga aacgtataat gaatgatatc ttctgaaatc tgttcaggaa atttaataat
     7081 tctcatatca ataatatatc atttaatttt gacactgata atttatacca tatacacaaa
     7141 tccaactaca tttttaacac tccagataaa tgattttcaa attttatagc taaattctca
     7201 ctattagcca gcttcattgc agtaatacac ttcttcattt ctagaatagc tttattgctc
     7261 ctattcttct ttaattcata taaatttttt gaataatgaa acactaattt ctcgtaaatc
     7321 tcagtttccg taaaacaact atgatttaac tgtttttcaa aatacaacgc atcaatatac
     7381 tcatctcttt caatacttat gatataacaa tttaatagca ttgttgagtg taaccttcgg
     7441 tagtttggta aatccttgta aaattctgaa cgtttacaca tttctcttga taaaagcatc
     7501 attgtttgat gattcaatac atctacagta ttcgcaaata acagtagttc gtaacaaccc
     7561 caatattcta cagagaatag gtagtctgat aaatattgga tatcagattc atcatagtaa
     7621 cttttgtctg ataagtcctg taaacgaatt tttattaaaa tagtatttag agtataaaaa
     7681 gtctcacgct tttcgatttt ttctacttga gagattaata acttttccat acctgacacg
     7741 ttccttgctg aaacaaataa actaatcttt tctaagattt cattaaactc atctctctga
     7801 aagtcgtttg ctgcatacat aaactcatca ataggcatat ttatcgtatt taaagctgac
     7861 ataaacttac taattgtcaa atctgtattt tcacgttcaa agcgggaaat atgagatact
     7921 gatacgccta actttgcgat atcttttaag actaatcccc tagactctct aaatttctta
     7981 aataattttc cataatcttt cataaaaagc acctcttttg catatacgag aatttcccag
     8041 ataaacttaa aagtattata tcatatagtg agataggagg ttaatttcta tgaataaaga
     8101 aagtttttta gctatcttac ttctaatttt tgaaagcatt attgtaattg ctgttggcta
     8161 aacaaataga aaataaagac accacaaaag ttagactttc gatgtctaac ttttgtggtg
     8221 tagttaaggt atgatgttgt tctctaataa gggtataata taaaaaagac tctatgattt
     8281 ctgtagtagg taaaaccact atagagatta tagagctttt tgagtgtata caaaaactag
     8341 ttctttattg gaacaaagtc aacaactaat ctagtattgg ttgcagcggc aatttcttcc
     8401 aatgttttat atgttggatt agtggtgcca ttctctatac gtcactttga gaaggtaaat
     8461 tttaaaatcc tctttatcat aactttttac taaaatagcc agaacatcac attctactat
     8521 cattcttatt tctcatcttc gtccattgaa agcacagaca agaaggcttc ttgtggtacc
     8581 tccaccgaac cgatggcttt catacgtttc ttaccggctt tttgtttttc gaggagttta
     8641 cgtttacgtg aaacgtcacc accgtaacat ttagccaaga cgtttttacg aagagctttg
     8701 atatctgtac gggcaacaat tttttgacca atagccgctt ggataggaac ttcaaattgt
     8761 tgacgtggaa taattttctt aagtttatca acgataagtt ttccacgttc gtaggcaaat
     8821 tctctatgga caataaagct aagggcatcg accttatcac cattaaggag aatatccatt
     8881 ttcaccaatt gtgaacgacg atactctgac aattcatagt caaaacttgc ataaccacga
     8941 gttgatgact tcaatttatc aaagaagtca aagacgattt cagcaagtgg aatttgatag
     9001 ataacgttaa cacgattatc atcaatatat tccatggttt caaaatcacc acgtttacgt
     9061 tgcgccaact ccataacagc accaacatac tcttgaggaa ccataatttg agctttgaca
     9121 taaggctctt caatggtatc aatacgtgta ggatctggaa attcagatgg gttggacact
     9181 tcaagcattt caccgtcagt agtgttaaca tggtaaacta ctgatggtgc agtcatgatg
     9241 agatcgatgt taaactcacg ttccaaacgc tcttggataa catccatgtg aagaaggccc
     9301 aagaaaccac aacggaaacc aaaaccaagg gcttgagacg tttcaggctc aaattgaaga
     9361 ctggcatcat tcaattggag cttttcaaga gcctcacgca agtcgttata tttatttgac
     9421 tcaattggat aaagaccagc aaagaccatt gggttcattt gcttataacc atgaagtggt
     9481 tctgcggctg gattatccgc aagtgtcact gtatcaccga cacgagtatc cgcaactgtc
     9541 ttaattgaag ctgctacata accaacatct ccagtcgcaa ggtagtcacg gccaacagct
     9601 ttaggagtga aaataccaac ctcagtaacg tcaaaggtct tgccattaga catcatttga
     9661 atcttatcgc ccgttttaac cattccgtta accacacgca cttggagtat gacgccacga
     9721 tacgcatcat aaacagagtc aaagataagg gcttggagag gtgcttccac atcaccttgg
     9781 ggcgcaggaa ctttctcaac aatttgttcg agaatctctt cgataccaat gccagcctta
     9841 gctgatgcaa gcacagcttc cgaggcatct aatccgataa catcttcaat ctctgtacgt
     9901 acacgctcag gatctgccgc tggaaggtcg attttattga taactggtaa gatttccaag
     9961 tcattatcaa gtgccaagta aacattggca agtgtttgtg cttcaatccc ttgagctgca
    10021 tctaccacca agatagcacc ctcacaggcg gcaagggaac gtgacacctc ataagtaaag
    10081 tccacatgtc ccggtgtgtc gataaggtgg aaaatataag tctcgccgtc tttagctttg
    10141 tagttaagct caatggcatt cagtttgata gtgataccac gttcgcgctc aagatccata
    10201 ctatcaagga gttgtgcctg catctcacga cttgatacag tctcagtctt ttccaagata
    10261 cggtcagcaa gcgttgattt accatggtca atatgagcaa taatcgagaa gttgcgaatc
    10321 ttctcctgtc tttgttttaa ttcttcaata tttggcattt tattctttcc tagttcttac
    10381 ttgtgattgt taaaaaacga accgtcacct cctattatac aaaaaagata ggcatttgcc
    10441 tatctctaat atctgcttta tgactgcatt taatccttct tatttcttaa aattatcatt
    10501 gtagtgctta ttaataatag ctgaacgctt gttctctatt gaactacttg aaaatggagc
    10561 taaaccaagg gttagtacaa taattcccaa tagaataaga ctaaaaaacg ggtgctcagc
    10621 aatatagtgt aagatgtctg atataggaat ccacctttaa aaacataatt atttataact
    10681 atattatcag aaacattatg ttttatcaag caaaaaaaga gagccattcg ctctcccttt
    10741 taaccttaat ggaattgcat accaccatca acgatggttg tttgacctgt gatgtagttt
    10801 gagtcaggtc cagctaggaa gctaacggct gctgcaacat cttcaggttc tgacaaacgt
    10861 ttgagggtaa tatctttagc aaaagtttgc ataccctact catcatcttt accagcattt
    10921 taccaacttc gtgggaaatg tcaaacatca ttggagtctt aacgatacct ggtgcataag
    10981 catttacagt tatacctgaa tcagctaagt cacgcgccaa agtttgagta ataccacgaa
    11041 ctacgaattt agttccacca tatacagtta agttagggtt accaacgaca ccagcttgag
    11101 aagttgcatt gataatttta ccaccatgac caagtgcttt aaattgtgct tgtgcagctt
    11161 gagcacccca gataacacca ccgacattga tgttaaatgt acgttggaac tgttcttcag
    11221 taattgtatc gagaggtgtt gttggagcca caccggcatt attaataaca acattcaaat
    11281 caccaaagtg atcaacaact ttttggaaag cagctgctac ttcagcttgt ttagatacat
    11341 cagctacaac tgcaaatgct ttatctgctg acaattcagc aacagctttt tctgcagttt
    11401 cagcgttgta gtccaatact ccgactctaa aaccatcttc aaccaaacgt tttgcaatcg
    11461 caaaaccaat accttgacct gcacctgtaa caatagcaac ttttgacata cgaaatcccc
    11521 ctctaccaat tggagtcaca agcttagtaa gaagccttat ctcaattgga atacgctaag
    11581 ttagtcaagt tctggcaaag tcattttcat aggctttgtc ttaactcatt tagaatctta
    11641 ccactttatg aaagcgttgt taataatttg tcatgctttt tgaaagcaaa taagaccacc
    11701 actagtgacc ttatgtgtat tatttttcaa acttaaaccc tagtgcttcc atatcaccta
    11761 ggccacctaa ggtggtaacc ttagtatatc ctcgttcttt cagtactcct gcagcaaatt
    11821 cagcacgaga tcccatttta caataaagat aaattgaatc gtctttttta gctggaatgt
    11881 cagctgtgaa aaactgcgtg tgaggtatta ataaagcatc cttaacatga ccttctgcgt
    11941 actcttctgg agtcctgaca tcaattaata gtccatcctg agctaattct gattgaatct
    12001 gtgctatatc catcctactc accaaaccaa atcttaattt ctcgagccgc agattcttct
    12061 gaatcagagc catgaacgat atttggaatc atgtcaccat ctggtgctgt tgcaaagtct
    12121 ccacgaatcg ttccaggagc agcatcccca ggattagttg ctcccatcat atcacgccat
    12181 gacttaataa cacctgggcc ggacataata ccaataactg ctggaccact catcatgaat
    12241 tcagaaatac tagggaaaaa aggtttatca gccaattggg cataatgttc tttaagacgt
    12301 tcttcgtcaa gcatcagcat ctccatacgc tcaataacga agccacgtcg ctcaattcga
    12361 tcaagcactt gaccaattag atggcgttta acagcatctg gtttaataat aaagaatgtt
    12421 ttttgcatat tcccaacctt catcgttttc tttccatttt atcataagaa gtatcatttt
    12481 tcagagctaa accttatata ttctaaaact atatccacag caagaaatta actatttttc
    12541 attagttccc ataagaaata atatagatgt aaatagacat ttcgaggtaa atttaatgac
    12601 aaaatctaaa ttccaattag tcgattctct tcttcgtcct gcggatctcc gtaaatacaa
    12661 ggacgaaatc gagcatcgtg acgacatcca gtatcctttc tatgatgacc ttcctggtta
    12721 tcaagaaact gaaactgcat ctattaagcg aatgtggctg accaaaaagc taacggaatt
    12781 gacatcctta ccgatgggga gtttggacgt tctatgtggc acttggactt tgtctgggga
    12841 ctcaaaggta ttgaacgcta cattgctgag catggttata cttttaaaga ccatgatggt
    12901 ggtcaatatg aaacacgtaa agatatcggt attcgtatca ctgagcctct ctcaggtaaa
    12961 aaccaccact acctagatat ttacaaattg gttaaggctg aagctggtga tgaagatacc
    13021 aaacaaacta tctggggacc tgctcatgcc tacactgaac ttgctatctt tgatcgattg
    13081 gctgttcctg gacaagtcta tgaaacaaac gaagaactca aaaaaggttt gattaatgcc
    13141 tataaagaat tcttagatga atacaaggct gttggtggta aaatcgttca atttgacgac
    13201 tgcctctggg aactttttga cccatcaaac cctgcaagtt tctactcaga cggcaatggt
    13261 gatttggcag aattagccga tgaatttgtt gctatcaata atgaggttgt tgactatact
    13321 cacgaacttg gtttaacggt ttggacacac aactgtcgtg gtaattatga aatccgttct
    13381 gctgctgaag gaacttacga agacatcgct aagaaattct tggcagagca acactatgac
    13441 tgcttcttcc ttgaatggga tagcgataca gctggtgata tcaaagctct ggaagccctt
    13501 aaagacagta aagctgaagt tgtatttggg ctattgtctt cttaaacgac tgacctagat
    13561 gacgaagaac gtgttctcga tttgcttgaa aaagcgagtc aaatccttcc aaaaaaacgt
    13621 ctcttcctct ctcaccaatg tggtttcgcc tcatgtgact caggtaatga gctggcaaca
    13681 cctcaacaat gggctaaaat caaacaaggt caagaaatcg ctaagaaatt ctttggctaa
    13741 tcgatatttc tattcgctcc tctctaaaac gaaaagcctt cactcttgtg agggcttttt
    13801 atgttagcat caagcatcta taaaagtttg caaatcctta agagctcttt ctgcgatttt
    13861 ttcataacgc tctttcttgt cacgaatacg tgggccttct aattctttga taataccaaa
    13921 gttaacattc attggttgga aatgtttgct ttcagcatgt gtcacataat atggaaggct
    13981 accgattgct gttgtatgag ggaaaataac ttcatcttca cccttaaaaa gacgggctgc
    14041 attgattcca gcaaccaaac ctgaggcagc tgattcaaca taaccttcaa caccagtcat
    14101 ttgtccagca aagaacagat tagggtttga ttttgattgg aaggtctgtt taagcaagtt
    14161 tggcgaatcc atgtaagagt tacggtgcat taccccataa cgaacaaatt ctgcattttc
    14221 aagacctgga atcatttgga agacacgttt ttgctctccc catttgaggt gggtttggaa
    14281 accaacgata ttgtagaggc taccagccgc attgtcctga cgaagctgaa caaccgcata
    14341 aggtgtcttg aagtcaccat cacgtggacc catataatct tcaggatact ccaaaccaac
    14401 tggtttcata ggaccgtaga gcattgtttt aataccacgt ttagccataa cctcgatagg
    14461 catacaccct tcgaaatact tttctttttc aaaagaattc aaaggagctt cttcagctgt
    14521 agtcaaggcc tcatagaagg ccatgaactc ttccttggtc attggacagt ttagataagc
    14581 tgcttcaccc ttatcatagc gtgacttaag gtaaaccttg ttcatgtcga tagttgcttt
    14641 atcaacgatt ggtgcagcgg catcatagaa atagaacccg tctccaccgt taagctcatg
    14701 aatcttttca gctaaagcat cagaagttag gggacctgaa gcaataactg taatagcatc
    14761 atcaggaatt tctgtgattt ctttacggat aacttcaatt aagggatgac tttcaatttc
    14821 agctgtcact gcttctgcat agccttcacg gtccaccgcc atggcaccac ctgctggcac
    14881 acggtgagct tctccattac gcataatgat agagtccaaa cgacgcattt cttcttttag
    14941 aagccctaca gcattggtca agctatctcc acggaaagag ttagagcaaa ccaattctgc
    15001 aaaatttgtt gtcttatgct gtggtgttgc tttgacccca cgcatttcat aaagttttac
    15061 tggaatacca cgtttggcaa tctgataagc cgcctcggat ccggccaaac cagctccaat
    15121 cacgttaata taatctgctt ttgattgaga catgacacta atacctcttc ggaaacaaga
    15181 tgaaatcctg ctcccacaaa tctttcttca tttttactct tagtagtata gcaaaaaact
    15241 cctcatctgg cgactaggag tcatctgtat ttaaaagggg taaaatgata gtcactttag
    15301 caccacccgt gccattgtca tttgcaagag aaagactacc atagtgtaaa cgaataatat
    15361 cattagcaat agtcagacca aggccactat gattgcgact ctgtctgctt ttatcctctt
    15421 gataaaatag ctgagtagcg ttttcaagag attcaaggga aaatccagga ccagaatcaa
    15481 ggcatataaa cttgaattca tcttcttcta ccctagcggt caggagcaac tgactgccac
    15541 tgggtgtatg ctctacggca tttgaaacaa tattcataat agctcgattc aacaaggact
    15601 tatcccaatt gcctatgctt tctttcgcaa tttccttctt gtcaaatacc acattgattt
    15661 gtttcgtttg agctaatgac aaggtttgat cgtaaatgtc ttcaacaaat tccttaactg
    15721 gaacttcttc aagcgtcagg gtcttcttca aactcatttt gttgagttct gacaactctt
    15781 ttacataagc atcaacctgt gcaatacctt tttgaaaatg ctctaataac tccgtttgat
    15841 tttcatccaa ggacgtcata gctaagagtt ccgcatttcc acgagcaact gttaggggcg
    15901 tctttaagtc atgtgtcagg gcagaaatct gattttgttt atcttgctct gccttccaat
    15961 tttccatcaa agactcacga agtgctatac gcatatgatc caaaccactt aaaacctgat
    16021 taaattcctt aattgtagac tgagaagttt gaaaatccaa atcttgttgg gaaatttttt
    16081 cagtaaccct taatataggt ttaagttgct gactcaattt atttgcataa taaaaagtta
    16141 aaataataaa tattattaag atagatacaa acattgaacc aatcatcata agatcagcat
    16201 tgggaaaatg ttggttcatc cactcattac ggtaccgagg tgatagttga taattaacaa
    16261 tgactatgcc atctgaccgt tcaaaagact gaaaatagcc gtatttctca ccgtgagcat
    16321 tcttgaattg gtaatttagt aaggattctt cttgcaagtt aacaagcatg ttagactttt
    16381 taagcttaaa atccctagtt aaaaagacat aactcgtgcc atcaggtaaa atctcgggat
    16441 taaagacctt agaagtttca atatcacttc tcacagcaga caaatcactc tcaacttgat
    16501 ttgctggaat cacaactcca aaacgaaaag acaagctgaa caaatacaaa ataagaagac
    16561 tgctgattac agagagaact gtaagactga cgacataaga taacaagatt gttcttagag
    16621 agtgttctcg tttttttatt agtgccactt gtaaccaatc ccccaaactg tttcaatagg
    16681 attttgccca acttctttaa gctttgcacg gatattcttg atatgttcag ccactgctgc
    16741 cggactgcct ttatcctcat agccgtacaa atgcgtgtag atttgttctt ttgaaaagac
    16801 ttggccctta ttttcagcta aaaactggca aataccatat tccgactttg tcaaatctaa
    16861 caactgattc tcaatataaa gctcttgagc agacaagtca aactgaaact ccccaagtga
    16921 aagcttatgg tgacgctcac gatgttcacg tctcaagtga gctgcaacac gcgcttggag
    16981 ttctttaacc ccaaatggtt tgcaaatgta atcatccgca ccataactca acccttggac
    17041 aatgtctgct tcttgcgttt tagctgtaat aaagaggatt gggcaatcca cctgatttcg
    17101 aatctcatgg caaaactgta gaccgtcaac atcaggcatc ataatatcca gtaaaatcag
    17161 gtcaaatcga ggtaaagagt tcttatccaa atctaaaaca cttgtaagcc ctgtcacatt
    17221 atggttttgg agctctaaag cctttacaac caattgaaca atatcttttt gatcatcaat
    17281 aacaagtatt cgagccatag cctctccttt ccttcaaagt tatccttatc atatcatcta
    17341 tagaagataa ctgacaaggc gtaaagtaga taaatatggg ttgggtaaaa aacatagaac
    17401 aaatattttg accctttccc tctttgaccg ttataagaaa gcattaaagg tgctgaaaat
    17461 atttccatcc attcaaagta tttgaatatt aaatcgtgaa aagaaggtct acttaaaaca
    17521 atcgccatta gcagccaaac gagactaaca ctcataaaag caagcacttc tttcttaaga
    17581 ttcctatgac aaagatacat agcgataccg gtcaaaagca accacgttcc tccatcattg
    17641 ataaatgtat ggactggcaa tactgtgaaa ttgagtaaat ttagtagaaa accaaacata
    17701 ggtttgttca cacttagcag ataaaaaggc accattaacc atggaagcaa caatggaaaa
    17761 agtaaagttg gtatcccttt aaggtatttc ttttcttgaa tccatgcaat cccttgaaga
    17821 gcaacgagca aaattgcgaa tgacgacagc atcatatttt gtggaaagaa accatctggt
    17881 ctaactagag gatgtagaaa attatagaat ccaaattgaa tcagtcccat cacaattgct
    17941 aaagaataaa tctttaggaa gtatttcttc cggttatggg tatgaataaa accctcaatc
    18001 aca
//
