MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AEW31026.1 short-chain_acyl-CoA_synthetase BGC0000407 NRP 98.0 100.0 584.0 7.3e-167
AAF08801.1 YngI BGC0001103 NRP + Polyketide 93.0 100.0 557.0 1.2e-158
ABS74201.1 YngI BGC0001095 NRP 75.0 99.0 450.0 2.8e-126
CAH10130.1 feruloyl-CoA_synthetase BGC0000268 Polyketide 41.0 95.9 198.0 1.9e-50
KGO40476.1 AMP-dependent_synthetase/ligase BGC0001205 Polyketide 35.0 99.7 176.0 7.8e-44
CAQ52626.1 type_I_polyketide_synthase,_loading_module_and_modules_1-3 BGC0001066 Polyketide:Modular type I 36.0 94.5 172.0 1.1e-42
ABJ90146.1 MoeA4 BGC0000805 Saccharide 38.0 97.9 171.0 1.9e-42
antaF putative_Acyl-CoA_ligase BGC0001455 NRP + Polyketide 38.0 95.2 170.0 3.3e-42
AIL50189.1 putative_5-aminolevulinate_CoA-ligase BGC0000213 Polyketide:Type II 36.0 101.7 165.0 1.1e-40
BBD17766.1 AMP-ligase BGC0001919 NRP + Polyketide 36.0 95.2 160.0 3.4e-39
ATY46587.1 polyketide_synthase BGC0001666 Polyketide 37.0 94.1 159.0 9.9e-39
ADC79613.1 BafX BGC0000028 Polyketide:Modular type I 36.0 97.2 158.0 2.2e-38
ADI58647.1 5-Aminolevulinate_CoA_ligase BGC0000187 Polyketide:Type II 37.0 97.9 156.0 4.9e-38
AGL76720.1 fatty_acid_CoA_ligase BGC0001137 Alkaloid 34.0 96.2 156.0 4.9e-38
AWX24488.1 acyl-CoA_ligase BGC0001695 NRP 36.0 95.2 156.0 6.4e-38
BBA21084.1 putative_5-aminolevulinate_CoA-ligase BGC0001740 NRP + Polyketide 35.0 98.3 155.0 1.1e-37
AAM54075.1 polyketide_synthase BGC0000020 Polyketide 37.0 91.7 155.0 1.4e-37
AAX98210.1 acyl_CoA_ligase BGC0000052 Polyketide 34.0 98.3 155.0 1.9e-37
AQZ37113.1 polyketide_synthase BGC0001511 Polyketide 37.0 91.7 154.0 2.4e-37
BBD17745.1 AMP-ligase BGC0001918 NRP + Polyketide 36.0 95.2 154.0 2.4e-37
ACF35445.1 mbcAI BGC0000090 Polyketide 34.0 96.2 154.0 3.2e-37
ABV97151.1 AMP-dependent_synthetase_and_ligase BGC0000137 Polyketide 35.0 92.4 152.0 1.2e-36
QBF51769.1 type_I_polyketide_synthase BGC0001856 Polyketide:Modular type I 35.0 92.4 152.0 1.2e-36
WP_010639243.1 AMP-binding_protein BGC0000958 NRP:Cyclic depsipeptide + Polyketide:Modular type I 36.0 95.2 151.0 1.6e-36
ADM46356.1 polyketide_synthase BGC0000106 Polyketide 36.0 91.0 151.0 2.1e-36
AKA54630.1 AMP_dependent_CoA-ligase BGC0001216 NRP + Polyketide 36.0 94.8 151.0 2.7e-36
ABB86408.1 GelA BGC0000067 Polyketide 35.0 93.4 149.0 1e-35
AFV30247.1 polyketide_synthase BGC0000075 Polyketide 35.0 91.7 149.0 1e-35
AHH25595.1 PKS BGC0000957 NRP + Polyketide 36.0 95.5 149.0 1e-35
AAO06916.1 GdmAI BGC0000066 Polyketide 35.0 93.4 148.0 1.3e-35
CQR60497.1 Polyketide_synthase,_type_I,_modules:_loading,_1,_2_and_3 BGC0001287 Polyketide 35.0 89.0 148.0 1.3e-35
AAY28225.1 HbmAI BGC0000074 Polyketide 35.0 93.4 148.0 2.3e-35
CAA60460.1 polyketide_synthase BGC0001040 NRP + Polyketide 34.0 93.8 146.0 5.1e-35
ABV99085.1 thioester_reductase_domain BGC0001007 Polyketide + NRP 34.0 93.1 146.0 6.6e-35
CAI94682.1 putative_polyketide_synthase BGC0000141 Polyketide 34.0 92.1 145.0 1.1e-34
TXD00261.1 AMP-binding_protein BGC0001877 Polyketide 32.0 92.1 145.0 1.5e-34
AAC68815.1 FK506_polyketide_synthase BGC0000353 NRP 34.0 91.4 143.0 5.6e-34
AGY30675.1 Ann3 BGC0001298 Polyketide 35.0 93.8 143.0 5.6e-34
ABP55493.1 thioester_reductase_domain BGC0001006 NRP + Polyketide 33.0 97.6 142.0 9.6e-34
CCP20047.1 divK_protein BGC0001119 Polyketide:Modular type I 32.0 91.4 141.0 2.8e-33
ONK09689.1 Beta-ketoacyl-acyl-carrier-protein_synthase_I BGC0001647 Polyketide 34.0 93.4 139.0 6.2e-33
ASZ00147.1 polyketide_synthase BGC0001785 Polyketide 33.0 92.8 139.0 8.1e-33
AAQ84158.1 PlmJK BGC0000123 Polyketide 36.0 80.3 138.0 2.4e-32
CAE02600.1 p-nitrobenzoate_CoA_ligase BGC0000024 Polyketide:Modular type I 30.0 95.5 136.0 9e-32
ACR50792.1 putative_acyl-CoA_synthase BGC0000163 Polyketide 33.0 95.5 136.0 9e-32
AFV52199.1 acyl-ACP_synthetase BGC0000081 Polyketide:Iterative type I + Polyketide:Enediyne type I 32.0 87.9 134.0 3.4e-31
CAO85890.1 aryl-coA_ligase BGC0000110 Polyketide:Modular type I 33.0 78.6 133.0 5.8e-31
ATY72527.1 AMP-ligase BGC0001574 NRP 33.0 87.9 133.0 5.8e-31
ATY12791.1 long-chain_fatty_acid--CoA_ligase BGC0001504 Polyketide 31.0 97.6 132.0 9.9e-31
EFL06871.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000300 NRP 32.0 93.1 131.0 2.9e-30
AAF86393.1 FkbB BGC0000994 NRP + Polyketide 33.0 91.4 130.0 4.9e-30
BAO66547.1 cyclohexanecarboxylate-CoA_ligase BGC0000042 Polyketide 34.0 97.2 129.0 6.4e-30
EYT83445.1 Triostin_synthetase_I BGC0001213 Polyketide 32.0 94.1 128.0 1.9e-29
ADI58632.1 5-Enolpyruvylshikimate-3-phosphate_synthase/CHC-CoA_ligase BGC0000187 Polyketide:Type II 30.0 95.2 127.0 3.2e-29
AGN74880.1 3-hydroxypicolinic_acid:AMP_ligase BGC0000459 NRP:Cyclic depsipeptide + Polyketide:Trans-AT type I 31.0 94.5 127.0 3.2e-29
PKY07881.1 hypothetical_protein BGC0001544 NRP + Polyketide 32.0 97.9 124.0 2.1e-28
AAF81723.1 putative_acyl-CoA_ligase_EncH BGC0000220 Polyketide:Type II 40.0 59.0 124.0 3.5e-28
ABC34346.1 long-chain-fatty-acid--CoA_ligase,_putative BGC0001102 NRP:Beta-lactam + Polyketide:Modular type I 32.0 83.1 121.0 2.3e-27
orf5 benzoate-CoA_ligase_family_protein BGC0001420 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 34.0 92.8 120.0 5.1e-27
APZ78718.1 benzoate-CoA_ligase_family_protein BGC0001420 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 34.0 92.8 120.0 5.1e-27
AEF33098.1 3-hydroxypicolinic_acid:AMP_ligase BGC0001039 NRP + Polyketide 30.0 91.0 119.0 8.7e-27
BAI63284.1 putative_peptide_arylation_enzyme BGC0000434 NRP 31.0 93.8 118.0 2.5e-26
CAC17498.1 putative_AMP-binding_ligase BGC0000324 NRP 31.0 93.1 117.0 4.3e-26
CBF87076.1 conserved_hypothetical_protein BGC0001290 NRP 30.0 98.3 116.0 5.6e-26
AGE11892.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000366 NRP 29.0 90.3 116.0 9.6e-26
BAH04171.1 AMP-binding_ligase BGC0000450 NRP 31.0 93.4 115.0 1.3e-25
AET98914.1 putative_AMP-binding_ligase BGC0000415 NRP 35.0 69.3 114.0 3.6e-25
SSTG_01180 acyl-CoA_synthetase BGC0000597 RiPP:Proteusin 35.0 93.1 113.0 8.1e-25
NP_626687.1 acyl-CoA_synthetase BGC0000595 RiPP 36.0 90.7 112.0 1.4e-24
WP_003976362.1 acyl-CoA_synthetase BGC0000596 RiPP 36.0 90.7 112.0 1.4e-24
CCA53797.1 Long-chain-fatty-acid--CoA_ligase BGC0001801 NRP 31.0 91.7 111.0 3.1e-24
ADZ13540.1 YtkG BGC0000466 NRP 26.0 94.1 99.0 1.2e-20
AAL61889.1 unknown BGC0001411 Saccharide 31.0 72.8 99.0 1.2e-20
QCT05736.1 Tri3 BGC0001983 Other 38.0 46.9 89.0 1.3e-17
QCC62990.1 AMP_dependent_ligase BGC0001966 NRP 26.0 99.0 87.0 3.7e-17
AXL88825.1 hypothetical_protein BGC0001895 Polyketide 26.0 91.7 85.0 1.4e-16
PPE_RS11475 aminotransferase_class_III-fold_pyridoxal_phosphate-dependent_enzyme BGC0001993 NRP 28.0 105.5 81.0 2e-15
AAZ55900.1 non-ribosomal_peptide_synthase:Amino_acid_adenylation BGC0000359 NRP 27.0 81.0 81.0 2.6e-15
ACM79810.1 ZmaO BGC0001059 NRP + Polyketide 26.0 94.1 78.0 2.2e-14
ABL74940.1 NRPS BGC0001048 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 31.0 64.8 77.0 3.8e-14
AEH59100.1 amino_acid_adenylation_domain-containing_protein/NRPS BGC0000385 NRP 25.0 95.5 77.0 4.9e-14
AAY93445.1 non-ribosomal_peptide_synthetase_PvdL BGC0000413 NRP 31.0 70.0 77.0 4.9e-14
WP_039806856.1 non-ribosomal_peptide_synthetase BGC0002001 NRP + Polyketide 26.0 93.4 77.0 4.9e-14
QCX41915.1 Mhr9 BGC0001956 Polyketide 32.0 55.9 76.0 6.5e-14
ADJ63842.1 Serobactin_synthetase BGC0000424 NRP:NRP siderophore 28.0 93.4 76.0 8.4e-14
AFK57212.1 DidA BGC0000985 Polyketide + NRP:Cyclic depsipeptide 32.0 59.0 76.0 1.1e-13
AOE23577.1 FoxBI BGC0001598 NRP + Polyketide 31.0 64.5 74.0 2.5e-13
AGZ15459.1 putative_non-ribosomal_peptide_synthetase BGC0001036 NRP + Polyketide 27.0 99.7 73.0 7.1e-13
WP_054234643.1 non-ribosomal_peptide_synthetase BGC0002014 NRP + Polyketide 24.0 97.9 73.0 7.1e-13
AHH34187.1 fatty_acyl_ACP_ligase BGC0001161 Polyketide:Modular type I 28.0 65.5 72.0 9.3e-13
ACA99172.1 polyketide_synthase BGC0001160 Polyketide:Modular type I 32.0 63.4 72.0 1.2e-12
CUX96957.1 TmcJ BGC0001829 NRP + Polyketide 29.0 89.3 72.0 1.2e-12
AHH34188.1 fatty_acyl_ACP_ligase BGC0001162 Polyketide:Modular type I 28.0 66.2 71.0 2.1e-12
EGJ35087.1 Fatty-acyl-ACP_ligase BGC0001163 Polyketide:Modular type I 27.0 66.2 71.0 2.7e-12
AAX31555.1 acyl-CoA_ligase BGC0000336 NRP 39.0 40.7 71.0 3.5e-12
AEF33080.1 putative_peptide_synthetase BGC0001039 NRP + Polyketide 29.0 87.9 71.0 3.5e-12
ADN13832.1 Polyketide_Synthase BGC0001164 Polyketide:Modular type I 30.0 66.9 71.0 3.5e-12
AHB38511.1 adenylation-thiolation_bidomain BGC0000345 NRP + Polyketide:Modular type I 28.0 90.7 70.0 4.6e-12
AFV52195.1 acyl-CoA_synthetase BGC0000081 Polyketide:Iterative type I + Polyketide:Enediyne type I 27.0 90.0 69.0 7.9e-12
AXN93611.1 PuwC BGC0001953 NRP 29.0 70.0 69.0 7.9e-12
AHD05617.1 putative_non-ribosomal_peptide_ligase_domain_protein BGC0001033 NRP + Polyketide 25.0 91.7 68.0 2.3e-11
AAR87760.2 ZmaK BGC0001059 NRP + Polyketide 29.0 55.5 68.0 2.3e-11
ALD82526.1 non-ribosomal_peptide_synthase BGC0001212 NRP + Polyketide 29.0 94.1 68.0 2.3e-11
WP_107406787.1 non-ribosomal_peptide_synthetase BGC0001567 NRP 27.0 85.5 68.0 2.3e-11
AFK57213.1 DidB BGC0000985 Polyketide + NRP:Cyclic depsipeptide 31.0 66.2 67.0 3e-11
WP_079164394.1 non-ribosomal_peptide_synthetase BGC0001567 NRP 25.0 83.1 67.0 3.9e-11
AWI62626.1 nonribosomal_peptide_synthetase BGC0001943 NRP 31.0 66.6 67.0 3.9e-11
OAP25805.1 Long-chain-fatty-acid--CoA_ligase BGC0001658 Polyketide 28.0 68.3 66.0 6.7e-11
AXN93598.1 PuwC BGC0001952 NRP 29.0 70.0 65.0 1.5e-10
BAV56017.1 ATP-dependent_b-aminoacyl-ACP_synthetase BGC0001597 Polyketide 26.0 78.6 64.0 2.5e-10
CAD15508.1 polyketide_synthase/non-ribosomal_peptide_synthetase BGC0001014 NRP:NRP siderophore + Polyketide:Modular type I + Polyketide:Iterative type I 25.0 67.2 64.0 4.3e-10
WP_006051172.1 AMP-binding_protein BGC0001999 NRP 28.0 72.1 63.0 7.4e-10
OAL11475.1 non-ribosomal_peptide_synthetase_module BGC0001570 NRP 25.0 81.7 62.0 9.6e-10
AMB48444.1 long-chain-fatty-acid--CoA_ligase BGC0001357 Polyketide 29.0 66.6 62.0 1.6e-09
CAJ88192.1 putative_peptide_synthetase_NRPS5-4-3 BGC0000151 Polyketide:Modular type I + Saccharide:Hybrid/tailoring 34.0 37.6 61.0 2.1e-09
CBD77754.1 hypothetical_protein BGC0000974 NRP + Polyketide 28.0 67.6 61.0 2.8e-09
AIR74919.1 long-chain-fatty-acid-CoA_ligase BGC0001559 RiPP 28.0 67.6 61.0 2.8e-09
AHN85651.1 Phn2 BGC0000122 Polyketide:Modular type I 29.0 56.9 61.0 3.7e-09
CDE97356.1 plipastatin_synthase_subunit_C BGC0001686 NRP 23.0 104.5 60.0 4.8e-09
AAY42393.1 Acyl-ACP_synthetase BGC0001000 NRP:Lipopeptide + Polyketide:Modular type I 26.0 73.8 59.0 1.1e-08
AFR69331.1 nonribosomal_peptide_synthetase_SpiA BGC0001045 NRP:Cyclic depsipeptide + Polyketide:Modular type I 28.0 64.1 59.0 1.4e-08
CAD17792.1 probable_non_ribosomal_peptide_synthetase_protein BGC0001754 NRP + Polyketide 29.0 64.1 59.0 1.4e-08
KFL51881.1 beta-ketoacyl_synthase BGC0001711 NRP + Polyketide 27.0 66.6 59.0 1.4e-08
ABD65965.1 acyl-CoA_ligase/dehydrogenase_fusion_protein BGC0000341 NRP 34.0 37.2 58.0 1.8e-08
AFV96135.1 AMP-dependent_synthetase/ligase BGC0001064 Polyketide:Modular type I + Polyketide:Type III 29.0 64.1 58.0 1.8e-08
ARU81115.1 CylA BGC0001566 Polyketide 29.0 64.1 58.0 1.8e-08
AKL71650.1 NocQ BGC0001703 Other 27.0 67.9 57.0 3.1e-08
AEC04356.1 polyketide_synthase BGC0000178 Polyketide:Trans-AT type I 29.0 61.4 57.0 4.1e-08
ACG60773.1 NRPS(C/A/PCP) BGC0001058 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 27.0 65.2 57.0 4.1e-08
AWS21283.1 acyl-CoA_synthetase BGC0001934 Polyketide 29.0 64.5 56.0 9e-08
AZY91992.1 putative_fatty_acyl-AMP_ligase BGC0002022 Polyketide 29.0 64.5 56.0 9e-08
AEZ53969.1 putative_AMP-binding_domain-containing_protein BGC0000144 Polyketide:Modular type I 36.0 34.1 56.0 1.2e-07
AAG02356.1 peptide_synthetase_NRPS7 BGC0000963 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 25.0 93.1 56.0 1.2e-07
CBW54660.1 Acyl-CoA_ligase BGC0000971 NRP + Polyketide:Modular type I 27.0 72.8 55.0 1.5e-07
ATY72525.1 non-ribosomal_peptide_synthetase BGC0001574 NRP 33.0 41.0 55.0 1.5e-07
ADD82966.1 BatY BGC0001099 NRP + Polyketide:Modular type I + Polyketide:Trans-AT type I 26.0 90.0 52.0 1.3e-06
AQW35047.1 Acyl-CoA_synthetase BGC0001675 Polyketide 28.0 67.9 52.0 1.7e-06
BAW27672.1 NRPS(A-T-C) BGC0001764 NRP 28.0 59.7 52.0 1.7e-06
AKL71645.1 NocL BGC0001703 Other 26.0 71.4 51.0 2.9e-06
AQX77690.1 NocL BGC0001704 Other 26.0 69.0 49.0 8.4e-06