LOCUS       c00016_JAJBPP0..       21749 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJBPP010000023.1 Bifidobacterium breve strain MSK.22.82
            FBOGENJA_23, whole genome shotgun sequence.
ACCESSION   JAJBPP010000023
VERSION     JAJBPP010000023
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 03:56:38
            Original ID  :: JAJBPP010000023.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 16726
            Orig. end    :: 38475
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..21749
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="neighbouring"
                     /product="RRE-containing"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..21749
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     protocluster    1..20273
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[26726:26999](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10273
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20273
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             complement(631..1035)
                     /locus_tag="ctg16_20"
                     /transl_table=11
                     /translation="MGWKGNRSRTIRKAVTFSEEEWRWVADSLKVENRQRIQAGLRPVG
                     WMTFARNRIRCAHRVNITVPANLHDVSAQLARIGNNVNQIARHANTTRETDLAMLSRVF
                     DELRQAERLVAGLSIRVETDVDPKGVPEWL"
     CDS             1324..1830
                     /locus_tag="ctg16_21"
                     /transl_table=11
                     /translation="MAKPRERNRAMRAIADNALDAELEALRRKRGELSRLGILLDDMRW
                     AAERFRDAAQSFCDDHHMPRAQLVRTLRMEPRETGMAFHAVTPDYGQANPADSHGEIHD
                     GEDSAVESGGRPASAADAPETALTEDNAATENAADAVDAGTSGSIGLDPEGLRFGFPRP
                     GGYAG"
     CDS             1769..2191
                     /locus_tag="ctg16_22"
                     /transl_table=11
                     /translation="LDWTRRGCDSVSRVLAATLDDIGDIREVTAMPMLLVMLGLSLATG
                     VIRMLMRGVASCLALLAHPLRLVVFLANSVFTAFAMLSGLLMLAFLLMHFLAGSDAPAL
                     DGSFALIVAAFLTAVLASMLMDWCDARLRRRSARHG"
     CDS             complement(2307..3866)
                     /locus_tag="ctg16_23"
                     /transl_table=11
                     /translation="METAIIERPVMADEGMDESNIVMLDVGLIDPNPANPRRDVGDVSE
                     LADSIRAQGIRQNLLVTPTLQGRYLLVIGHRRLAAAKLAGLSRVPAVVADLSEREQREL
                     MLVENSQRADLTVIEEADGYQGLLDLGVGVDEAAQRTGRSVSLVRRRLKIAAIGENARS
                     KAGTAQLSIDDWETIADFDRYPDLQERLAEAAGGKNWNMAVKHARQERTWREWLDTARA
                     ELERMGIDAADEQPNTDNWYDSPKGLRRTTMLTTGDIAKAIDAWRDSHDGATPVVGVRA
                     EGASWARGIVLYETVDEEAETAAREAREARWREEREREERETAPAKEFARASRDLRIAF
                     VTHLMELKSQPKGIGRAVALLSARFALDALTEGFDQWDGHAEDVWEQITGIDTTGDDAD
                     AEEPEGETEDPLRASVTAMIAGDPQRAAFGLLYALAEERVSWETWRGAATIAEHAAPLY
                     EALETLGYRTSDTETEALNGSLAPIDDNDNGGDAGIRQDGEPDDDGTSQTDDASGKPED
                     AE"
     CDS             complement(3956..4969)
                     /locus_tag="ctg16_24"
                     /transl_table=11
                     /translation="MTVAYRGLPAPLAERMLQAGLFDILSAIGAGTRPRAMRYAHDHVV
                     WPLACSRRWAARNLTRGLRPPPACHALRLRSLRRVPRRSRACAATANQHAVFATARIVA
                     VHASGLSAYAHGRRVVSEMETTRKGPMDMNDMVDTRTTGTGLAKRVRDGFLQDRRELGP
                     AQAADKWFAPLMDRWNGLLSRDEGGFSHEERVTLAVLMTEYLSMRDALILASLHEMGGG
                     ELHMLYAKPHSMESAAVVMRELSRAFKDADYQPDTRRGERATALLESVTADAPDGYEAQ
                     PMASCAYLLWMADRSTAAAVRALKALALDDDCSLASLVLAASEHGIRPAWTERRRH"
     protocluster    4978..21749
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[31703:34693]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      14978..17967
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
     cand_cluster    4978..21749
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             5093..6418
                     /gene_functions="regulatory (smcogs) SMCOG1048:sensor
                     histidine kinase (Score: 106.3; E-value: 3.2e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_25"
                     /transl_table=11
                     /translation="MGSRRGKSSDEGQTLAVTPRDRLILWLRQLKGERLLRFTTTLICI
                     VGTMGVLIRDYVEERMAIGTGYSFIRFLNEGAGIWYFLILLVLGAINVTLRFRSPVALL
                     ALEFIELSLGVLFGVGLHSYTQVALILVLYLCIRLPLYAQAMCDLAMICMIAMQYMHPA
                     SLQPQYLALLYSVALAGIASSLLSIARDRRTANRLLSEARRKAAILAEEKNRTERRLRM
                     ANELHDSVGHGLTSIIALSQGGEDCIRNGGYSDSQLADALAEITSIAKDSLGDTRRILK
                     VFNEEESQPSLEQVGLEPVNQDDILRLRDWDDIRPVLEHIRSTGIIVVFTETGRRVEDP
                     RRSDLCFAVTREALTNALRHGAGLTRIAVSWNHYRDGGTAITIRNDGHVSGHGTTGEAS
                     GQSGKPTGGTGLQRLSQRLAKMGGTLSYGPYGNGWAVKALIP"
     CDS             6435..7142
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 168.2; E-value:
                     2.4e-51)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_26"
                     /transl_table=11
                     /translation="MKDARDDIIKVMLVDDMRGARTGFMMMLNNDPNIIVSSQAADGAQ
                     AIEFLRQSPQQLPDVILMDVRMPVMDGIEATGIIKEQFPQIQILILTTYDEDDYAFDGL
                     ARGASGFLLKDATPKQLRDAVHAVHNGDAVLTPRITGEVLNRGVRPISDNTRIKLLRSL
                     FDGLSKREYEVAELVAAGLSNQEIAEHLFIETASVRRTVSRILARMHMRDRVQIAIAWY
                     QSGLDQITGGKPA"
     CDS             7753..8070
                     /locus_tag="ctg16_27"
                     /transl_table=11
                     /translation="MTELQNLLTVKLHALAPIGVLKMRFAIALLPNPKALIMDEPLQTL
                     DRSGTNWICEQIRKQANRGVAVLIASEPDSRLRPITDDVVVLDKGTVVKEGSRGQLWKE
                     D"
     CDS             complement(8319..8882)
                     /locus_tag="ctg16_28"
                     /transl_table=11
                     /translation="LRHSSAIVRKRLLSDAKISLLGTCFAGEGSALVYRGLLDLSRCSM
                     VAAGMECMFLHGDLSPRRLSGSEGSKSMTMRSRSRSAFVMLASREALSDRSTSSSETVQ
                     NTRSPLSRGTWTHVPSSLMLMEAGSFEQFVGFPPRTITVRFGFLCVNGITFPYPDTARD
                     HQYMQGFGQFDPQGNGALAPPTST"
     CDS             9526..10014
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_29"
                     /sec_met_domain="Asn_synthase (E-value: 2e-17, bitscore:
                     55.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKHADIRPLNPDRSRHQALYSLSMQARMLNQVNRTFASNDITFRS
                     PYLDHGIADYALCAPISARTEGNLHKAVLYRALKGIIPETIFRRPVKGDHSYSLYLAWQ
                     RSKDALLDSIAGGVLDEEGLIDMPAIRRRASMPMPDITFLFEMQRVAAVERWLRYASR"
     CDS             10001..10273
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_30"
                     /sec_met_domain="PF05402 (E-value: 2.5e-11, bitscore: 35.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.6e-16,
                     bitscore: 50.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQADDTQTSISLRNQISLYPKEGGAIVFVNDTGEYLQVNEIGRII
                     LDGLMCGKTVEDCTNKIAEEYQADRQIIARDADRFLADMGKHVRL"
     CDS             10824..12467
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 286.4; E-value:
                     7.9e-87)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_31"
                     /transl_table=11
                     /translation="MTLLLPKYMTNFFQNGVFQVPQWPVIAGMLLLVTASGAISALQNY
                     QLQSTGEDIVRDARLALSKHLLRLPIREYDQRDSGDLLSRVSNDTSQLRNAFMQCTSAL
                     ASGFITVIGSAAFMAMLDPILFGTAITLLLTVFTLMLLSAKFIERASYDSQYTLGDLTS
                     TLNRDLAGIRTIRASNGFENENKVIAALINHVRLSGLKIARIQSIVNPLATIALQLAAI
                     IVFGLGLWRVTTGLLSVEKLTQFIMLLFISISPLSQIIYAGSQIGNSMAAMNRIREILD
                     IPEEKDPDTVVTTINEHMPLAHSSPCPPAVEFQHVYFSYESKPILHDLNLSISQGSVTA
                     LVGPSGAGKSTILQLIERFYDPSSGNINVLGKDITTCDRDDLRSHIAYVEQDSPALSGS
                     IRENLLLGSNDCSDDECRRALKSVNLSHLLDRSDKGLDMQIGENGIMLSGGERQRLAIA
                     RALLSTAKIILLDEATANLDADNERLITRLLAQVEGRTFIIVAHRLATIIDSDLIYVIN
                     HGRVIGSGTHKQLFENIPLYHNLATKQHIA"
     CDS             complement(12721..12870)
                     /locus_tag="ctg16_32"
                     /transl_table=11
                     /translation="MCDLRVLIGDVEGFGLRAMLKREIDRIVVQVLLLVHVVMMLKYVS
                     MSRN"
     CDS             13250..13426
                     /gene="allorf_29976_30152"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_29976_30152"
                     /protein_id="allorf_29976_30152"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNTAILEKPTVDVMDIDLDIDVEDLPVEQIDQIRLTSISLCTPGC
                     TSPNGGSGCSFCC"
     CDS_motif       13250..13345
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNTAILEKPTVDVMDIDLDIDVEDLPVEQIDQ"
                     /locus_tag="allorf_29976_30152"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13346..13426
                     /prepeptide="core"
                     /locus_tag="allorf_29976_30152"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-10.80"
                     /molecular_weight="2420.8"
                     /monoisotopic_mass="2419.1"
                     /core_sequence="IRLTSISLCTPGCTSPNGGSGCSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNTAILEKPTVDVMDIDLDIDVEDLPVEQIDQ"
                     /leader_location="[13249:13345](+)"
                     /alternative_weights="2438.8"
                     /alternative_weights="2456.8"
                     /alternative_weights="2474.9"
     CDS             14499..14744
                     /locus_tag="ctg16_33"
                     /transl_table=11
                     /translation="MLNWQFIYRKYSRKIVKACPHCNIIIMNLLNNMGLMKRFQFSILQ
                     IPQKELVCQMTINIPNIQIRLALAQIIISMRSMNIT"
     CDS             14978..16603
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     316.3; E-value: 6e-96)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_34"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.6e-40, bitscore:
                     130.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9e-18, bitscore:
                     56.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLPKYVEKQFLNPIFEPDEYSAVINYPTRSDAAANLIDTPIAG
                     ERIISVNIPEENNEHCISLSQIGIRANKEGLYAVDLYTGQKIRIRAHNTVYPPAQAPNE
                     VRLLIEIMNEGARLWNPWSWNSLDSFPYRPRVRYGHIILSSRSWRLDELRESELASCKH
                     WREKWNVPRYCLAVSQDMRLLLDLDNPLHQTLLINESRKDKQLLVQEIPAGGNNPDAVW
                     GWMRKDGQSICSEIVFNFHKIDHKFSNSSTSMIPYRKIISRNNHIFLPGNENWLSCRIY
                     MPPENMVNYLKNNLTDILDCFNSSTVKHSFFVRYADRQGTHLRIRINGNDTDFNRLTSI
                     LVKSIVDGDARTYDFNEYIPEVNRYGGIQMMELTHQCFTTDSMNALQQIDKKGMEYDLD
                     SLAALCVMLTGFGNGYAKSKSFDLQEGKRWADYLNLSTSHDKEYQKNRKIWIESIKSVI
                     LHESKQVSKLDDLYKAYRDLGYMMKKSCNNYTATSSPTRVIGSHLHMCLNRRYGPNPEI
                     EDRLLRIAQSVLTSINQSIKYGEF"
     CDS             16609..17967
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     288.9; E-value: 1e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_35"
                     /sec_met_domain="LANC_like (E-value: 1.1e-41, bitscore:
                     134.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQDQSKFLPPEIEKQFFYIIDELCHRLIDPKQLKSIVDQPGNH
                     EPLFDTSVWAPCTISHGLCGTSIFYSILANKYESFRAVAHNHLLLATSTINWCINGGVM
                     GGPSGLLAAAQIASRSPMDYSKLREQLTAWICRCQLYLINRYRSSLGNGVPWLAYDIMN
                     GICGNLRILLDENSTNARETINLSVKYLCDLVLTSNSQGMPGWWVPGNLQPTKQDENEY
                     PDGDLNVGVAHGAAGILGTLVSVFNYGYTDTRVMDSIKRIMEWTFHWTQHADDFDYWPA
                     RIPTNCQIQDDVLSPLPTRAGWCYGTPGIAVEMLRASTLLDDVDTTGHIIDILSSHLSS
                     PTNQWHIAGPTFCHGYAGVLYSVFKAWTLCGSEVLRNIGSNMANNLLAMADECSPFVYQ
                     HWMYSNTPSHKINLKKLDNVGLLEGSSGIGLVLYSICNQGDSSANWDRVFALS"
     CDS             17976..18845
                     /locus_tag="ctg16_36"
                     /transl_table=11
                     /translation="LISINVEIFKKELLKNLNAQIDYFSPLFWINDSERKQFPWGPLVE
                     LLQIINTLTEEDILKYFDLDKLAIIGRELWNHRFPFNPYILLGRSILSDLCIRNNKTRI
                     LWADIRNNDTIRATEEPLLWCQIPQLERDYLAECLQKKDSSLLYKSSLISYLKARSEGR
                     LNDRVSAYYLTHLIIYCTNYGKRNFFPLHVRDILFQDAQAVAKESFSKKNYDLLAEAEA
                     SKCALGLHDQHTLKYAMYLFGLFSRYRCIPCFEIEDFTSLSKKDKFRLSYHTMLASSLL
                     VSILSRQE"
     CDS             18847..19860
                     /locus_tag="ctg16_37"
                     /transl_table=11
                     /translation="MLYLSAFTVPFLFALALWPVVSVALTVPVLAMLYHRDNRLGLPAI
                     LSAYGTVLYAIGLLCLTLYPLPADPVAFCAVHHLKPQLDLFRFVADIRTDGLDAVLQIV
                     MNVVFFLPLGFIVRRVFHRGLPTATVAGFLVSLLVETMQLTGTLGVFPCAYRLFDVDDL
                     VWNTSGALAGYGCALAFDRLLPMRESDAATVTHPGLVRRLVAFLVDMGLVMSAALPLAV
                     AANVIHALVSGVRPGAAADRVLGGLGFSGLMFLLMLFVFEVLVPWLRDGRTLGGGYTHM
                     TCETVPRSGVRRILFYMARFVVFACLALAGIPWQPVIALALLTFWMAFRRMPYDLI"
     CDS             19978..20556
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 118.9;
                     E-value: 3.1e-36)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_38"
                     /transl_table=11
                     /translation="MTSPGGAATRDGDLLARVASGDERAFETLYGRYAAAVRAFVRVRV
                     PDAGTAEEVCADVWLGCWRSARAFRGDAKVLSWLLGIAKRQIYMRVRRVRPNVTALDDA
                     PEPRDDGPSPETAVLSEAGVDDLTALLRRLPVELVETATLAWLHGLSYRQIADLSDVPE
                     GTVKSRISRARRLLRAQLDRQNDADGKER"
     CDS             20563..21390
                     /locus_tag="ctg16_39"
                     /transl_table=11
                     /translation="MTDHIDETTDRLTDGTPDGHLLAALDAVERSHSEDAPPAAAVMAR
                     IRSSRSPLDGPAWSWARSLRLFMLLLGRQSRVVPWQVVPATLALMAFAGLGARFFAVGW
                     GATVVSRAFCSMVLAGVLLSVTMAFGDSRADMISSATPLGTGAVTLVRLVFILACDVVF
                     GLMVTAVMGAQGYGTFGVLLVGWLSPLLLVAGVGAMLAIRFSTGVGFGVGLLLVAVIRT
                     DLLGLTGLPAAGWIDMTRPFGQPLLAVTGLMACAAAVAFSGRLSEARMAAAAV"
     CDS             21523..21747
                     /locus_tag="ctg16_40"
                     /transl_table=11
                     /translation="MAGMIRAQARRIGMGLLTMPVACGIAVAAAGIMVSGVWSRTQTLT
                     VVNWLAQLMVIGAGVCVAVALTGDPLVEAS"
ORIGIN
        1 tgacgccgag cgtcgcgagt tcgcggcgga atcccgcgaa gtcatgggcg ttcatgcagg
       61 ccgtgtcgat gctggtgcgc agccggtcct tgaggttgcc gcctctggcg ctcaggtgga
      121 gttccccgat cgacggggcc acgcgcccgg actgttccgg catgagggtg tgcagcccgt
      181 attcgcggca cagccggtcg ctgatcttcc gccattcgcc caaggtccct ttccgcagac
      241 gcagggcctt gcccgtgatc cggtctgccg ggcagatgag gatgtggttg tgcatgtggg
      301 acctgtcggt gtgggtggcg atcacgtagt cgtgcgtgcc tccggtgatc tcccggacga
      361 accgttcccc gatcagatgc gccaatcggg gcgtgacttg atcggtggga tcgaacgatt
      421 ggatcacgtg cagcgccaac acggccccct gccggcgtga gccacctttc gtggcgtcca
      481 acgcacgttc gaagccgcgg gcgatggact cggcgtccgt gatgtcatcg ccgacggtgg
      541 tcgaggccca ccggtagccg tcggttttgg ccgggttcgt cacgtaggcg atgctgcggg
      601 cgagcgtgct tttgatcttg ccaatcttga ctacagccat tcgggcaccc ccttggggtc
      661 aacatcggtc tccacccgga tgctcaggcc cgcgaccagc cgttccgcct ggcgcagctc
      721 gtcgaacacg cgcgagagca tggccaggtc cgtctcccgc gtggtgttcg cgtgacgggc
      781 gatctggttg acgttgttgc cgatcctcgc tagttgggcg ctcacgtcat gcaggttcgc
      841 gggcacggtg atgttgacgc ggtgggcgca tctgatccgg ttgcgggcga acgtcatcca
      901 tcccactggc ctgagcccgg cctggatgcg ctgacggttc tccactttga gcgagtccgc
      961 cacccaccgc cattcctcct cgctgaacgt gaccgccttg cggatcgttc tggaacggtt
     1021 gcctttccag cccatcggtg cctcctcgta tcgggttcca cgggtgtccc gtaatcggcc
     1081 ccgagcctcg cggggccgcg ccggtgtacg tacacgggcg atgcttgctg cacaccaacc
     1141 gcccctccgg ggaggggatg gttgcgcacc ggtcagtttc accttcgcgc cacgccatgc
     1201 gcggcggact ccatgtcacg tttcgcatgc cggcgccggt tccgtttcgt gtccgccggc
     1261 atcatggccg gcgtcattct acgatgcggg gcaacgaaga acaatcaccg tgaggagacc
     1321 gtcatggcga agccgaggga acgcaaccgg gcgatgcgcg ccatcgcaga caacgcattg
     1381 gatgccgagt tggaggcgct tcggcgcaaa cgcggcgaac tgtcgcgttt gggcatcctg
     1441 ctggacgaca tgcgctgggc cgcggaacga ttccgcgacg ccgcccagtc gttctgcgac
     1501 gaccatcaca tgccgcgcgc ccagcttgtg cgcacgctca gaatggagcc gagggagacg
     1561 ggcatggcgt tccatgccgt cactcccgac tacgggcagg ccaatcccgc cgatagccac
     1621 ggcgaaatcc atgatggcga ggattcggcc gtcgaatccg gcggccgacc ggcatccgcc
     1681 gccgatgcgc cggagactgc cctgacggag gacaacgccg caacggagaa tgcggctgat
     1741 gccgtggatg ctggcacgtc cggttcgatt ggattggacc cggaggggtt gcgattcggt
     1801 ttcccgcgtc ctggcggcta cgctggatga cattggcgac atacgggagg tgacggcgat
     1861 gccgatgctg ctggtgatgc ttggcctgtc gctggcgacg ggcgtgatac gcatgctgat
     1921 gcggggcgtg gcctcgtgcc ttgccctgct cgcgcacccg ttgcggctcg tggtgttcct
     1981 tgcgaactcc gtgttcacgg cgttcgccat gctgtcggga ttgctcatgc tggcgttcct
     2041 gctcatgcat ttcctcgccg gttcggacgc tccggcattg gatggctcgt tcgcgttgat
     2101 cgtcgccgcg ttcctcacgg ccgtgcttgc gagcatgctc atggattggt gcgacgcgcg
     2161 gctccgacga cgctccgccc gccacggctg agcgtcacct gccgccgctt ggctccggca
     2221 ggtgcgggcg cgcatgcgcc gtcacgtttc gccgtccgcg cccggactgg gcggaaccct
     2281 tattccggtt ccgcccagtt cgtcgcctat tcggcgtctt ccggcttgcc ggatgcgtcg
     2341 tcggtctgcg acgtcccgtc gtcgtccggt tcgccgtcct gccttatgcc ggcatccccg
     2401 ccattgtcgt tgtcatcgat tggcgcgagg gagccgttga gggcttcggt ctccgtgtcc
     2461 gaggtgcggt aaccgagcgt ttccaaagcc tcgtacagcg gtgcggcgtg ttccgcgatg
     2521 gtcgccgcgc cgcgccacgt ttcccagctg acgcgttcct cggccaacgc gtagagcagt
     2581 ccgaacgcgg cccgttgcgg gtcgccggca atcatcgcgg tgacggacgc gcgtaacggg
     2641 tcttcggtct cgccctccgg ttcctcggca tcggcgtcgt cgcccgtcgt gtcgatgccg
     2701 gtgatttgct cccagacgtc ctcggcgtga ccgtcccatt ggtcgaatcc ctcggtgagc
     2761 gcatcgagcg cgaatctcgc ggacagcagg gcgacggccc tgccgatgcc tttcggctgg
     2821 gatttcagtt ccatgagatg cgtcacgaac gcgatgcgca aatcacggct tgcccgcgcg
     2881 aactccttgg ccggtgccgt ctcgcgttcc tcgcgttccc gttcctctcg ccaacgcgcc
     2941 tcccgcgcct cgcgggccgc ggtctccgcc tcctcgtcca cggtctcgta caggacgatg
     3001 ccgcgcgccc atgacgcgcc ttcggcccgc acccccacga cgggcgtggc accgtcatgg
     3061 gagtcgcgcc atgcgtcgat ggccttggcg atgtcgcccg tggtcagcat cgtggtgcgc
     3121 cgcaatccct tcggcgagtc ataccagttg tccgtgttcg gctgttcgtc ggccgcgtcg
     3181 atgcccatgc gttccaattc ggctcgcgcc gtgtcgagcc attcgcgcca tgtccgctcc
     3241 tgccgggcgt gcttgacggc catgttccag ttcttgccgc ccgccgcctc ggcgagccgt
     3301 tcctgaaggt ctggataccg gtcgaagtcg gctatggtct cccagtcgtc gatgctcagc
     3361 tgggcggttc cggccttgct tcgagcgttc tcgccgatgg cggctatctt caggcgtcgg
     3421 cgcaccaatg acacggaacg gccggtgcgt tgcgccgcct catccacgcc cacgcccaaa
     3481 tcgagaagcc cctgatagcc gtcggcctct tcgatgacgg tcaggtcggc gcgctggctg
     3541 ttctccacga gcatgagttc gcgttgctcc cgttccgaca aatcggccac cacggcgggc
     3601 acccggctca atccggcgag tttggcggcg gcgaggcgac gatgcccgat gacgagcagg
     3661 tagcgtccct gcaacgtggg agtgacgagc aagttctgcc ggatgccctg cgcgcgtatc
     3721 gaatccgcga gttccgacac gtcgcccacg tcacggcgcg ggttcgcggg gttcgggtcg
     3781 ataagcccca catccagcat gacgatgttc gattcgtcca tgccttcgtc ggccattacg
     3841 ggacgttcga tgattgcggt ttccatgttt gtctccttga aaaaatcgga tgattgggat
     3901 tggtcggggc ttccggcgtc ggaagccccg accggattga atccgcggcc gacgctcagt
     3961 ggcggcggcg ttccgtccat gcggggcgga tgccgtgttc gctggccgcg agcacgaggg
     4021 acgccagcga acagtcgtcg tccaaggcca aggccttgag cgcgcgcacc gcggcggcgg
     4081 tcgaacggtc ggccatccac agcaggtacg cgcacgacgc catcggctgt gcctcgtatc
     4141 cgtccggggc gtcggccgtc accgattcca gcaacgccgt cgcgcgttcc ccgcgtcgcg
     4201 tgtccggctg gtagtcggcg tccttgaacg cccgtgacag ttcgcgcatg accacggccg
     4261 ccgattccat cgaatgcggc ttggcgtaca gcatgtgcag ttcgccgccg cccatttcgt
     4321 gcagcgatgc gagtatcagc gcgtcccgca tgctcaggta ctcggtcatc agcaccgcca
     4381 gcgtgacgcg ctcctcatgg gagaagccgc cctcgtcgcg cgacagcagg ccgttccacc
     4441 tgtccatcag gggcgcgaac cacttgtcgg ccgcttgcgc cggtccaagt tcacgccggt
     4501 cctgaaggaa cccgtcgcgt acgcgcttcg ccagcccggt tcccgtcgtg cgggtgtcca
     4561 ccatgtcgtt catgtccatc ggtcctttcc gtgtggtttc catttcggac accacccgcc
     4621 tgccatgcgc gtaggcggag agaccggagg cgtggaccgc gacgatccgg gccgtagcga
     4681 agacggcatg ctggttcgcc gtcgcagcgc aggcacggga gcggcgcggg acacggcgca
     4741 gggaacgcag acggagcgca tggcatgctg gtggtggccg caaccccctc gtcagattcc
     4801 gcgcggccca ccgccgcgag catgcaagcg gccagacaac atggtcatgc gcgtagcgca
     4861 tggcccgggg ccgcgttccc gcgccgattg cggagagtat gtcgaacagc cccgcctgga
     4921 gcattctctc cgcaagcgga gcgggaagtc cgcgataagc tactgtcatc cgtagatgtc
     4981 aaacaggagc caggtcatgg acatgcgagc ctcgaatcgt agataatggg agagctgtat
     5041 tctcggacaa cgaagaaggc gtaaggtgca ggttgcgagg aaccgcctca ttatgggctc
     5101 acgccggggt aagtcatcag atgagggaca aacgctggcc gtcaccccgc gggatcgatt
     5161 gattctatgg cttcgtcagc tcaaagggga acgcctgctt cgtttcacga caactctgat
     5221 ctgcatcgtc ggcacgatgg gcgtgctgat ccgcgattat gtggaagagc ggatggcaat
     5281 cggcacagga tattcgttta tccggttcct caacgaggga gcggggatat ggtacttcct
     5341 catactgctg gttttaggag ccataaacgt gacgttaagg ttcagaagcc ccgtggcgtt
     5401 gctggccttg gaattcattg agctctccct gggcgtcctg ttcggcgttg gcctgcactc
     5461 atacacgcag gtcgctctta tcctggtgct ttatctgtgc attcggcttc ccctgtatgc
     5521 tcaggccatg tgcgatctgg ccatgatctg catgatcgca atgcaataca tgcatcccgc
     5581 ctctctgcag cctcagtatt tggcgttact gtattccgtc gctttggccg gcatcgcatc
     5641 ctcactgttg tccatagcgc gggaccgtcg aacggcgaat aggctactgt ccgaggcacg
     5701 gcgaaaggcc gcaatactgg cggaggagaa gaatcgtacg gaacggcgcc ttcgcatggc
     5761 caacgaactg catgacagcg tcggtcatgg attgacctcg atcatcgcgt tatcgcaggg
     5821 aggtgaggac tgcataagga acggcggcta ttccgactcg caactggccg atgccttagc
     5881 ggagatcaca tcgattgcga aggacagtct gggtgatacg cgccgcatct taaaggtctt
     5941 caatgaagag gaatcgcagc catctttgga acaggtcggt cttgaaccag tgaatcagga
     6001 tgacatcctt cgtttacggg attgggacga tatcagaccc gtactggaac acatacgctc
     6061 aaccggaatc atcgtcgtgt tcaccgaaac gggaagacgc gtcgaggatc cccgccgttc
     6121 ggatttatgc ttcgccgtca ctcgcgaggc actgaccaat gcccttcggc acggcgcggg
     6181 actgacccgc attgccgtct cctggaatca ttaccgtgat ggcggaacag caatcacgat
     6241 ccgcaacgat ggacacgtct ccggacacgg caccaccggc gaggcatccg gtcaaagcgg
     6301 gaagccgaca ggtggaaccg gactgcaacg actctcccaa cgccttgcga aaatgggcgg
     6361 caccctgtcc tatgggccat acggcaatgg ctgggcggtc aaggcactaa tcccctgaaa
     6421 gaaacggaag aaccatgaag gatgcaagag acgacatcat caaggtcatg ctggtcgatg
     6481 acatgcgagg ggcgcgcacc ggcttcatga tgatgctgaa caacgatccg aacatcatcg
     6541 tcagctcaca ggccgcggac ggcgcccaag caatcgaatt cctacggcaa tcaccgcagc
     6601 aactgcctga cgtgattctg atggacgtgc gcatgcccgt catggacggc atagaggcga
     6661 cgggcatcat caaggagcaa ttcccccaaa tccagatact gatcctgacc acatacgatg
     6721 aggacgatta cgccttcgac ggattggcgc gaggggcatc cggattcctg ctcaaggatg
     6781 cgacccccaa acagctacgt gacgccgtac acgccgtgca taacggagat gcggtattga
     6841 caccgagaat caccggtgaa gtgctcaatc gcggggttcg gcccatatcg gacaacaccc
     6901 gcatcaagct gctgcgaagc ctattcgacg gactttccaa gcgggaatat gaagtcgcgg
     6961 aactcgtggc ggcaggcttg tccaatcagg aaatcgccga acacttgttc atcgaaacgg
     7021 catcggtacg acgcacggta agccgcatat tggccagaat gcacatgcgg gaccgagtcc
     7081 aaatcgccat agcctggtat caatcggggc tggaccaaat aacaggcggc aaaccagcat
     7141 aaaaatcacg atattcatct caaggattgt ggtgtttgtc atcttcagat gacaaacacc
     7201 acaatccttt tattggagaa tagagcgaac tggttaactg tctatgtcca tcgctcaagc
     7261 gaacggaaca aacctagcat atatcacgtc acttctgcca tcccctaaga tagggcagta
     7321 tccaaaaacc gttagggggg gggacttcga ttattgcggc tcgggtcaat cgaagaaagg
     7381 aaaacgatgt gccagctgcc cgattcggct tcacccatca tcgcatttga gaacgtctca
     7441 ttcaatcatg ccggtcgcga attgcatggg atctcatttg ccgcctatgc aggtcgagtc
     7501 accgttctga tgggagcgca tgacgctggc aaaacaactg ttctccggat gctgttggga
     7561 ctggatatcc cggattccgg atgcatatcc acctgtggca aaccctatgg cacatcccgt
     7621 ataccaaaaa acgttgtgag tgcaatgccc gaagccattt cacggtcccc gtattactcg
     7681 gccggaacct atcttcgttg gaaggcgctc tgggccggaa cgcctgatcc gcttcttgac
     7741 gggatcattc acatgaccga actgcagaat cttctcaccg tcaagctcca cgctctcgct
     7801 ccgatcggtg tcctcaaaat gcgattcgcc atagctctgc ttcccaaccc caaggccctg
     7861 atcatggacg aaccgctcca gacactcgat cgatcgggca cgaattggat ctgcgagcag
     7921 atacggaagc aggcgaatcg tggcgttgcg gtgctcatcg catccgaacc ggacagcagg
     7981 ctgaggccga ttaccgatga cgttgtggta ctggataaag gcaccgtggt aaaagagggc
     8041 tcccgcggcc agctttggaa ggaagactga aaaacgccag cggatcaccc gcttccctaa
     8101 ggtccatgtg tttggtgttt gtcatccgaa gatgacaaac accaaacaca ttcttggatg
     8161 taccatccaa atcaggttaa ctggaatggc atgcaccggc atgcaatccg gtcccatata
     8221 cagagcatga ggagaacgaa gatgaaggat tatgtacccc cggccgttga ggtcatcgca
     8281 tcattcaagg aagcaaccaa tggcgtatgg ttcggcaact atgtcgatgt tggcggcgcc
     8341 aaggccccgt tcccttgggg atcgaactga ccgaaaccct gcatatattg atgatcccta
     8401 gctgtatcag gatagggaaa cgtgatgccg tttacgcata agaacccaaa ccgtaccgtg
     8461 attgtccgcg gcgggaagcc gacgaactgt tcgaagcttc ccgcctccat cagcatcaat
     8521 gacgagggaa catgcgtcca agttcctctg ctgagtggcg atcgcgtgtt ctggaccgtc
     8581 tccgaagatg aagtgctcct gtcggacagc gcctcccgac ttgcaagcat cacgaacgcc
     8641 gatcttgacc tggaacgcat tgtcatggat ttgctgcctt cgctccctga cagccttcga
     8701 ggggacaaat ccccatggag gaacatacat tccatacccg ccgcaaccat actgcacctc
     8761 gacaaatcca ataggccgcg atatacgaga gcggaacctt cacccgcaaa acatgttccg
     8821 agcaacgaga tcttggcatc actaagaagc cgtttcctga cgatcgcgga tgagtggcgc
     8881 aatgaggcac cactatccgc cgatgtgtcc ggaggagtgg attccgccgc catcacatac
     8941 gtcttcgcca gcgagggggt tcgtatgccc ctgtatcatg aaacacccga cgatccaatg
     9001 aatcaggatt cccgatgggc cgagcgaatc tccgaggacg ttcggatgcc actcatcaaa
     9061 atcggccggg tcgtggatgg aaacagatca ttcgaacccg cagccggata tcccaacaga
     9121 gagatacctg aagaaccggt ctactggagc gatatcgaag gctatctcag ccgaatctcc
     9181 gaaatggaag cagacgcaag ccgtatccat gtcacgggtt tcggaggaga cgagctgttc
     9241 gcatccatgc catcctcatc atggagctgc ctgcgggaac acccgctacg gctacaggac
     9301 atccgaagac aatacagcgc cgattaccgg gtcccaccct atcaggcaat tctcgatctc
     9361 accgatggca ccgatctgca tgaggaatta cggtcatcgt tcctggacgc ggaacaaggt
     9421 catgaccatc gctcttcgcc ttgtggatgg catgatgcca tacgcattcc cgaattcctg
     9481 accgcgaaag ccaggaatat cctatatggc gccgttgaat cacaattgaa acacgccgac
     9541 attcggccat tgaaccccga ccgaagccgt catcaggcgc tctactctct gtcaatgcag
     9601 gcacgaatgc tcaatcaggt taatcggacg ttcgcctcca acgacataac gttccgctcc
     9661 ccctatctgg accacggaat cgcggactat gcgctatgcg ccccaatcag tgcacgcacc
     9721 gagggaaatc tacacaaagc cgtgttatac cgggcgctca agggcataat ccccgaaacg
     9781 atattccggc gtcccgtcaa aggcgatcac tcatattcac tgtatctggc atggcaacgc
     9841 tcgaaggacg cactgctcga ctcaatcgcc ggcggagtgc tggacgagga gggactgatc
     9901 gatatgccag ccatacggcg tcgagcttcc atgccgatgc ctgacatcac attcctgttt
     9961 gaaatgcaac gagtagcagc agtggaaagg tggctgagat atgcaagccg atgacacaca
    10021 gacaagcatc agtctgagga atcagatatc cctgtatccc aaggagggcg gggcgatcgt
    10081 cttcgtcaac gacaccggtg aatacctgca ggtcaacgaa ataggccgga ttatccttga
    10141 cggtctgatg tgcggcaaaa ccgtcgagga ttgcacgaat aaaatcgccg aagaatatca
    10201 ggccgacaga caaatcatcg cccgggacgc ggatcgtttc ctcgccgata tggggaagca
    10261 cgtgcgtcta tgagcatccc actacagccg gaagcgatca cacgagccaa ctttcacgac
    10321 cgcctgatag cgctgattgc catcatcatc ggcagacgga tggaacgaca gcaaatcgga
    10381 gagttctgcc gccggcttga aacgtggtcc gaacgatatc cgccggccga caccagcatg
    10441 gcggaacgtt accgcaatgc cgtatgcgcg gtaagccgca gatgccgaag ccagcagggt
    10501 tgtctgcttc ggtcgctctc cacagcggcg gcatgccgca tatctcgccg atccgtcaca
    10561 tggtgcaccg ggttcaccga tcgtcccttc cgcgcacacg cctgggtcga agccaacggc
    10621 acacccatcg gcgaacctga tgccgtcaga cggtacacca tcaccagaac cagttccgaa
    10681 cggaaagata cgcaatgacc gtcaacgacc aggacgacac catgcacatg aaacctgcct
    10741 ccatgtacaa tctgatttct cccctccgaa aataccgagg acggctggca ctcatcctat
    10801 gccttggagc cataggagcc gctatgacgc tgctcctgcc taagtacatg accaacttct
    10861 tccagaatgg tgtattccag gttccccagt ggcccgtcat tgccggaatg ctgctactcg
    10921 tcaccgcctc aggagcaata tcagccctac agaactacca acttcagagc acgggggagg
    10981 atatcgtaag ggatgctcgt ctcgcactaa gcaaacacct gctacgtctg cccatacgcg
    11041 aatacgatca acgcgactcc ggcgacctgc tcagccgtgt cagcaacgac acctcacaac
    11101 tgcgtaatgc attcatgcag tgcacatcag cccttgcatc aggcttcatc accgtcatcg
    11161 gttccgctgc gtttatggca atgcttgacc caatcctatt cggcacagcg atcaccctgc
    11221 tccttaccgt attcacgctc atgctgctgt ccgctaaatt catcgaacga gcaagctatg
    11281 acagccaata cacgctcggc gaccttacct ccacgctcaa tcgtgatctc gccggcatcc
    11341 gcaccatacg tgcttcaaac ggcttcgaga acgagaataa ggtcattgcc gccttgatca
    11401 accatgtccg cctgtccgga ctcaagatcg ccagaatcca gtcgatcgtc aatccactgg
    11461 ccacgatagc cctgcagctc gcagctatca tcgtgttcgg tctgggatta tggcgcgtaa
    11521 ccacagggtt gctatccgta gagaaactta ctcagttcat catgttgctg ttcatcagca
    11581 tctcaccgct cagccagatc atttacgcag gctcacaaat cggcaattca atggccgcaa
    11641 tgaaccgtat acgggaaata ttggatattc ccgaagaaaa ggaccctgac accgtcgtca
    11701 caacaatcaa tgaacatatg ccgctggcac acagcagccc ctgtccgcca gcagtggaat
    11761 tccaacacgt ctacttctca tatgaatcca aaccaattct gcacgacctg aatctctcca
    11821 tatcccaggg aagcgtcacg gcactcgtcg ggccctcagg cgcagggaaa agcacgatcc
    11881 tgcaacttat cgaacgtttc tatgatcctt ccagcggaaa catcaatgta ctcggcaagg
    11941 acataacaac ctgtgatcga gacgatttac gcagccacat cgcatacgtg gaacaagatt
    12001 caccggcact gtccggcagc atacgagaga acctacttct cggatcaaac gattgtagcg
    12061 atgatgaatg ccgacgggca ttgaaatccg tgaatctctc ccatctgcta gatcgatccg
    12121 acaaaggtct cgatatgcag ataggggaaa acggaatcat gctatcaggc ggagaacgcc
    12181 aaagactcgc catagcccgc gcccttcttt ccacggcaaa aatcatcctg ctcgacgaag
    12241 ccaccgcaaa cctggacgcc gataacgaac gccttatcac tcggctattg gctcaggtag
    12301 aaggccgcac ttttattatc gttgcgcatc gactcgccac aataattgat tccgatctca
    12361 tatatgtaat taaccacgga cgggttatcg gatcaggaac ccataaacag cttttcgaaa
    12421 atataccact ctaccataac cttgcaacaa aacagcatat cgcatgatca cggactgaga
    12481 atcatccaaa ttatatgcaa cgcgaaatta tggaacgtca tcgaccatgt cgaataattg
    12541 cataacaccg cggaccatga gattacgatg cttacacact gtctgaaaga gtgcccgata
    12601 agaacagtgg tctgtgcaca gctttcttga aaggcgttat acgggaaagc tattcagaga
    12661 gacaaagcca tatatatata cgctggcaga aaccaaaaca actagctcct attccctaat
    12721 ttaattacgg gacatactca catatttcag catcattaca acatgcacca aaagcagcac
    12781 ttgtactaca attcggtcaa tctctcgctt cagcatggcc cgtaatccaa atccttcgac
    12841 gtcgcctatc aaaacacgta aatcgcacat ttcaatatat cgtgaattta aaatctcggg
    12901 acatgttcat catcatgaca cgataacccc acaaaacaga agacatgact cccagcccga
    12961 tgaggtcgct gattcagcct cccacacaga aaaagcccgg aatacacact ccggtcatgc
    13021 atcgtcaaaa gacaagccca atggaaacag ccagaacaat tcaagctgtc atcgcaagat
    13081 gacaaatgac tgatgaatga ttgaatatcc aacacaaaag aacgagcata gtggtggagg
    13141 gaaaactcca actaaccaag agcatgcaat tagttaaaca ttttaaagga ctatttttat
    13201 gtcctcttgc caaacaattg catagtcagg aaaagaaagg aggtgaatca tgaataccgc
    13261 aattcttgaa aagccaactg tagatgttat ggatatcgat cttgacatcg acgttgaaga
    13321 tttgcctgta gaacagattg accagattcg tttgaccagc ataagtcttt gtacaccggg
    13381 ttgcactagc ccgaacggag gcagcggatg ttccttctgc tgctaatgca atagataagg
    13441 ttcgggtggg agatgataaa accctgtttc catctcccac ctgtttttat tcaaaagagg
    13501 tgttgcaatg agacaagaga aaaaagccat ggacgcaatt cccaacataa caattcgcac
    13561 ggcagcgctg ccatacctct caataacgca acaaatcaat cctttagaat ctcaaaaaac
    13621 tgaacttcta gcatatttaa gggatatata ctcaaatgag tatatatccc ttgcaatcat
    13681 tcatgcggca ccttctttat atcaatccgc gcatgacgct attactggtt cccagaacat
    13741 accatcagca cgaaagctga aaaaaatagt gttagcaacg agtaaatacg taaatcgagc
    13801 tttgagtcgc ccaactccct tcggtttatt cgccgaagtt ggtataggaa catttaatcg
    13861 aaaagacata ctaaccataa cacaagagga aaagatcatt catgcagacg ctgattacaa
    13921 atggctaaat ccattaatta gaaaactgga acagcactcg tctattctca ggcaactaat
    13981 gctgcatcgc aatgacctaa taaggaagca acataatcat tacatactat atacggttaa
    14041 caaagagagt atgtgcaata agcgtgtgga catcagatgc acgcccatta tcgacgacct
    14101 attaaatgat aaggacatca gtgtcaaaac cattcttgat cgactatcaa gacaattcaa
    14161 cgtggatgaa gacacctctc tgagcttgat taagcgtctt gtcaattcgg atatatttta
    14221 ctcaaatttg agaccagccc ataatggtga ggaacgtatt tcagaactgc ttgagaaact
    14281 atctcacatc gcaattcagg aagaagataa agacatagtg gagcaattag tggaaataaa
    14341 taataagctc cattccatct caggatacac ttatccaagt atgcaatcgt atcaagacac
    14401 cataaaagcc atgggaaaga tacagaaatc cgactcttat gttcattttc aggtcggaaa
    14461 cggaatatcc ataggtcttc cgaaaagcgt gcaaaaagat gctgaattgg caattcatat
    14521 atcgcaaata ctctcgaaaa atcgtaaagg catgtcctca ctgcaatatt attataatga
    14581 atttgttgaa caatatgggt ttgatgaaac ggttccaatt ctcgatctta cagatcccgc
    14641 aaaaggaatt ggtgtgccaa atgactataa atatccccaa tattcaaata cgactagctt
    14701 tagcgcaaat aataatatct atgaggagca tgaacattac ctagcatcac tattctatga
    14761 tgccataaca aagaacaaaa ccgaagttat actgacggat gaagacataa ataaacttca
    14821 atacgagaaa ttcgataagg aagattcgca agaaagcgcc gaactgtatt gcaccattgc
    14881 gtcaaaggac atgtccgcct tatcggaagg agactattta ttggttattg gcccaaaccc
    14941 cggatcacat gcatccggta gcactactgg ccgatttatg tctttattac ctaaatatgt
    15001 tgagaagcaa ttcctaaatc ctatatttga gccagatgag tatagtgcag ttataaacta
    15061 tccaacacgc tccgacgcgg cggcaaatct catagatact ccgatagccg gggaaaggat
    15121 tatatcagta aatattccag aagaaaacaa cgaacactgt atttcccttt cccaaatcgg
    15181 aatacgcgca aacaaagaag ggctgtacgc cgtagattta tatactggac aaaaaatccg
    15241 tatacgagcc cataataccg tttacccgcc cgcacaagct cctaatgaag taagactatt
    15301 aatagagata atgaatgagg gagcccgttt atggaatccc tggtcatgga acagcctgga
    15361 tagtttccct tatagacctc gcgtacgata tggccatatt attttatctt caagaagttg
    15421 gcgccttgat gaacttcgcg aaagtgaatt agcttcatgc aaacactgga gggaaaagtg
    15481 gaatgttcca cgttattgtc tagcggtaag tcaggatatg cgattacttt tagacttgga
    15541 caatccatta catcaaactc ttttaatcaa tgagtcgcgt aaagataagc agctcctagt
    15601 tcaagagatt ccagccggcg gcaataatcc ggatgcagta tggggatgga tgagaaaaga
    15661 tgggcaatct atttgcagcg aaatcgtatt caatttccat aaaatagatc ataaattctc
    15721 taattcctct acgagtatga ttccatacag gaagattatt tcacggaata accatatttt
    15781 tttgccagga aatgaaaact ggttatcatg ccgtatctat atgccgccgg aaaatatggt
    15841 taattatcta aaaaataacc tgaccgatat tttagattgt ttcaatagtt ctaccgtcaa
    15901 gcattccttc tttgttaggt atgcagaccg ccaagggact cacctaagaa taaggattaa
    15961 tggaaatgat acggatttca atagactcac ttcaatactt gtaaaatcaa ttgtagatgg
    16021 cgacgcgcgc acatatgact ttaacgaata catacccgaa gtcaatagat atggcggcat
    16081 tcaaatgatg gagttaacac atcagtgctt tactacggat tctatgaatg ctctacagca
    16141 gattgacaag aaggggatgg aatatgatct tgattcattg gctgcgctgt gcgtcatgct
    16201 gaccggattt gggaatggat atgccaaatc gaaatcattt gatttgcaag agggaaaacg
    16261 ttgggcagat tatttaaatc tttcgacttc tcacgataag gaatatcaga aaaatcggaa
    16321 aatatggatt gaatccataa aatccgtaat ccttcatgaa tcaaaacagg tatcgaaatt
    16381 ggatgatttg tataaagcat atagagattt gggatatatg atgaaaaaaa gctgcaataa
    16441 ttataccgca acctcctctc cgacccgtgt tataggcagt catctacata tgtgcttgaa
    16501 ccgaaggtat ggtccaaacc cggaaataga ggataggctg ctaagaattg cgcaatctgt
    16561 cctgacaagc atcaatcaat cgattaaata tggagaattt taataattat gtctaaacaa
    16621 gatcaatcaa aatttcttcc gccggaaatt gagaaacaat ttttttatat aattgacgaa
    16681 ctatgtcata gattaattga tccaaaacag ttgaaatcta ttgtggatca acccggcaat
    16741 cacgagccgc tttttgacac atcagtatgg gcgccctgca ccatcagtca tggtttatgt
    16801 ggcacctcta tattctattc catattagcg aataagtatg aatcattccg cgctgttgca
    16861 cacaatcatc ttttacttgc aacctccact attaactggt gtatcaatgg cggggttatg
    16921 ggaggcccct caggcctact agcagcagca cagatcgcat cgagatctcc tatggattat
    16981 tcaaaactac gtgagcaact aaccgcttgg atttgtaggt gccagttgta tttaattaac
    17041 agatatcgtt catctttggg gaatggtgtc ccatggcttg cttatgacat catgaatgga
    17101 atttgtggca atctccgcat tttattggat gagaatagta caaatgctag agaaactatt
    17161 aatttgtctg taaaatattt atgcgatttg gtacttactt caaactcgca aggcatgccc
    17221 ggatggtggg tgccagggaa cttacaacca acgaagcagg atgaaaacga atatcccgac
    17281 ggcgatttaa atgtaggcgt cgcacatggc gctgcaggaa ttttgggaac actagtaagc
    17341 gtctttaact atggttacac ggacacacga gttatggact ccattaaacg cattatggaa
    17401 tggacatttc attggacgca gcatgcagat gactttgact attggcctgc acgaataccg
    17461 accaattgcc agatacaaga tgatgtttta tcacctctac ctactagagc cggatggtgc
    17521 tacggtactc caggaattgc ggtcgaaatg ttaagagctt caactttact ggatgacgtt
    17581 gatacaaccg gacatatcat agacattctt tctagtcacc tttcatcgcc aacaaatcaa
    17641 tggcatatag ccggccctac cttttgtcat ggttatgcgg gtgttcttta ttccgtattt
    17701 aaggcttgga cactttgcgg aagtgaagta ctacggaata tagggtcgaa catggctaat
    17761 aatttattag ccatggctga tgaatgttct cctttcgtat accaacactg gatgtattcc
    17821 aatacaccct cgcataaaat taatttgaaa aaactagata atgttggttt attagagggt
    17881 tcttcaggaa ttggcttggt tttgtattca atatgcaatc aaggtgattc atctgcaaac
    17941 tgggatcgcg ttttcgcttt atcttaggac caatattgat tagcataaat gtcgagattt
    18001 tcaaaaaaga attactcaaa aatcttaatg cacaaattga ttatttttca ccgctgttct
    18061 ggataaatga ttcagaaagg aaacagttcc catggggacc tctggtcgaa ttactccaaa
    18121 tcattaacac tcttacagag gaagacatat taaaatattt cgatttagat aaattagcca
    18181 ttataggacg tgagctttgg aatcaccgat tccccttcaa tccttacatc ctactgggaa
    18241 gaagcattct ttccgatctg tgcatccgta acaataaaac ccgcattctc tgggctgaca
    18301 tccggaacaa tgacaccatc agagctacgg aagaaccctt gttatggtgc caaattcctc
    18361 agcttgagcg tgattacctc gcggaatgtt tgcaaaagaa ggattcatct ttattataca
    18421 aatcgtcact gatttcatat ctgaaagcaa gatcggaagg tagattaaac gacagagtca
    18481 gtgcatacta tttgacacat ttaataatat actgcacaaa ttacgggaaa aggaattttt
    18541 tcccattgca cgtaagggat atccttttcc aggatgccca agcagtggca aaagaatctt
    18601 tttccaaaaa aaattacgat ctgcttgcgg aagcagaggc atcaaaatgc gccttgggat
    18661 tacatgacca acacaccttg aaatacgcta tgtacttatt tggattattc agtcggtata
    18721 ggtgcattcc atgtttcgaa atcgaagatt ttacttctct ttctaaaaag gataaattcc
    18781 gcttgtcata tcacacaatg cttgcgtcgt ccttattggt ctcaatacta tcaagacagg
    18841 aatgatatgc tttatttatc ggcgtttacg gttccgttcc tgtttgcgtt ggcgttgtgg
    18901 ccggtggtgt ccgtggcgtt gaccgttccg gtgctggcga tgctgtatca ccgcgataac
    18961 cggcttggat tgccggcgat cctgtccgcg tatggcacgg tgctgtatgc aatcggcttg
    19021 ttgtgcctca ctttgtaccc gttgccggcc gatcccgtcg cgttctgcgc cgtccaccat
    19081 ctgaagccgc agttggacct gttccggttc gtcgccgaca tacgtaccga cgggttggat
    19141 gctgtgttgc agatcgtgat gaacgtcgtg ttctttctgc cgctcgggtt catcgtcagg
    19201 cgtgtgttcc atcgcgggct tcccacggcc accgtcgccg ggttcctggt ctcgctgctg
    19261 gtggagacga tgcagttgac gggaacgttg ggcgtgttcc cgtgcgcgta tcgcctgttc
    19321 gacgtggatg atctggtgtg gaacacgtcg ggcgcgctgg ccgggtacgg gtgcgcgctg
    19381 gcattcgacc ggctcctgcc catgcgtgag tcggatgcgg cgacggtgac ccatcccggc
    19441 ctggtccggc gtctggtcgc gttcctcgtg gacatgggcc tcgtgatgtc ggcggcactg
    19501 ccgttggccg tcgcggcgaa tgtcatccac gcattggtct caggcgtccg gcccggtgcg
    19561 gctgccgacc gcgtgttggg cgggttaggg ttctcggggc tgatgttcct gctcatgctg
    19621 ttcgtcttcg aggtgttggt gccctggctg cgggatgggc gcacgttggg aggcggctac
    19681 acgcatatga cctgtgagac ggttccgcgc tcgggcgtac gtcggatcct gttctatatg
    19741 gcacggttcg tggtgttcgc ctgtttggcg cttgccggca taccttggca gcccgtgatc
    19801 gcccttgcgc tcctgacgtt ctggatggcg ttcaggcgca tgccctacga cctgatctga
    19861 cgcccctccg ggcatgtcga tgcacgtgcc atgaaccgcc ggcgcgttcc ccgctacata
    19921 taccgatgaa catccgtcta cgatgtgctg tggaaggagc cgcatacgca ggatgacatg
    19981 acctcgcccg gtggggcggc gacgcgtgac ggggatctgc tcgcgcgggt cgcctccggg
    20041 gacgagcgtg ccttcgagac cctgtatggg cggtacgctg cggcggtgcg ggcgttcgtg
    20101 cgcgtgcgcg tgccggatgc cggcacggcc gaggaggtgt gcgccgacgt gtggttgggt
    20161 tgctggcggt cggcgagggc gttccgcggt gacgcgaagg tgctgtcctg gctgctgggc
    20221 atcgcgaaac ggcagatcta catgcgcgtg cggcgcgtac gcccgaatgt gaccgcgttg
    20281 gacgatgcgc ccgaaccgcg tgacgatgga ccgagtccgg agacggccgt gctgtccgaa
    20341 gcgggcgtgg atgatctgac ggcgttgctg cgccggctgc ccgtcgaact ggtggagacg
    20401 gccacgttgg cgtggctgca cggcctgtcg taccggcaga tcgccgattt gtcggacgtg
    20461 ccggaaggca cggtcaaatc ccgtatctcg cgtgcgcgcc gtctgctgcg cgcgcaactc
    20521 gaccgccaaa acgatgcgga tggaaaggaa cggtgaatcc cgatgaccga tcatatcgac
    20581 gaaacgaccg accgcttgac ggacgggacg cccgacgggc atctgcttgc ggcattggac
    20641 gccgtggaac gatcccattc ggaagacgcg cctcccgctg cggcggtgat ggcgcgcatc
    20701 cgatcgtcgc gttccccgtt ggacggaccg gcatggtcgt gggcgcgcag cctgcggttg
    20761 ttcatgctgc tgctgggccg gcagtcgcgg gtggtgccgt ggcaggtggt gccggccacg
    20821 ctggcgttga tggcgttcgc cggattgggg gcgcggttct tcgcggtcgg ctggggtgcg
    20881 acggtcgtgt cccgcgcgtt ctgctcgatg gtgctggccg gcgtgttgtt gagcgtgacg
    20941 atggcgttcg gggattcccg cgcggacatg atctcgtcgg ccaccccgtt gggtacgggg
    21001 gcggtcacgc tggtccggct ggtgttcata ctcgcctgcg acgtcgtgtt cggcctgatg
    21061 gtgaccgccg tgatgggcgc gcaggggtat gggacgttcg gcgtgctgct ggtcggatgg
    21121 ctgtcgcccc tgctgctggt cgccggcgtg ggcgcgatgc tcgcgatccg tttctccacg
    21181 ggcgtcggct tcggcgtcgg cctgctgctg gtcgccgtga tccgtacgga cctgctcggg
    21241 ctgacgggcc tgccggccgc gggctggatc gatatgaccc ggccattcgg gcagccgctg
    21301 ctggccgtca cgggtctgat ggcgtgcgcg gcggcggtgg cgttctccgg acgattgtcc
    21361 gaggcgcgca tggcggccgc ggccgtctga ccggattgaa gccgacgggc ctccggcggc
    21421 cgttcggcgt gtcgcgtgaa ccatgcggct gccgtccgct acctatcagg tgacggacga
    21481 taaggaacgg ccgtcgagct tcgcacttca aggagggacg gcatggcggg aatgattcgc
    21541 gcgcaggcca gacgcatcgg catgggattg ctgacaatgc ccgtggcctg cgggatcgcg
    21601 gtggcggccg ccggcatcat ggtatccggc gtgtggtcgc gcacgcagac gctgacggtg
    21661 gtgaactggc tcgcccagct gatggtgatc ggcgcgggcg tgtgcgtggc ggtcgcgttg
    21721 accggcgacc cgctggtcga ggcgagcga
//
