LOCUS       c00018_JAJGTF0..       15681 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGTF010000139.1 Limosilactobacillus reuteri strain M_81
            scaffold139, whole genome shotgun sequence.
ACCESSION   JAJGTF010000139
VERSION     JAJGTF010000139
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 10:44:44
            Original ID  :: JAJGTF010000139.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2237
            Orig. end    :: 17918
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15681
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[7237:12918]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..10681
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..15681
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15681
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(631..1170)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MNNDVEKVLYTQDQVNQRLDELANTLTEKYQGKFPVLVSVMTGAM
                     IFTSEMMKRLNFKLNVDYVDVSSYEESSESTGKVKLIQDLSHDIKDRPVLIMEDIIDTG
                     HTLKYLVALFANRGAKSIEICSLLDKPDRREVDVEADYVGFKVPNEFIVGYGLDFDGLY
                     RNLPYVGVLKRSVYEK"
     CDS             1372..2403
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 119.4; E-value: 3e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MLIIMKKVNLYIFLTLCSFAIFLLTTPSKVKAEVVDKQTQHQLQD
                     YMKDHHINGVMLVNGKDGKPVAIENHETTNKDQIVKADRLFPTASLQKIVTGTAVYQLR
                     QKKQLAWDTSLSKYYQQIDGSKDITIRELMNHTSGLINNDRPFEPLRGQKAQIAYMLKH
                     LKYDHTHTWDYQDVDYEILAAIVSKQTHQSYNDYIRKNFAKPLHLHQIKDFSEVSKKEI
                     PQPMDPTVDWHRVTVTTSSDFGAGNLFISPNDYWKFVYNEVLKDPKMINEYYHQAQHQE
                     VAYFGGVYFDGDVIRANGSIPGYNSCFVADYKTKRMIMLFSNNIDYLKLKAASDDILHN
                     YME"
     CDS             complement(2471..2881)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MNKIYFLCTGNSCRSQMAEGYARIFLKNKYEIQSAGLEAHGVNPL
                     AIEVMAEDNIDISHQYSKTIDPHYFKTANLIVTLCGDSKDRCPVIAPPTHSIYWPLPDP
                     AQATGTPEQQLQIFRQVRNEIKQRILALASNP"
     CDS             complement(3220..3714)
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MALGTYQQVKDALKNFGITDYTVIDHPATHTTEEADAYIAGHEGV
                     RTKTMFLKGKKKNFYMVIMDDKKPMDFHEFMALTGAKRVSMARPEYLQEQLGLAPGIVS
                     PFGLLNNEAHNVKVYFDKDIVDEPIQTFHPNENTHTIFIKTDDMFKFLKPIDFEPEIID
                     L"
     CDS             3899..4219
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MMILIFYNHNMLSYDREVITMSSKVQVNIDPELKQSAENIIKEIG
                     LTPTAVINGMYKQIVATGKIPLSFSLTPKQRTELELREVSKKIPVREVKTKEELEEFFN
                     ED"
     CDS             4209..4535
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MRTNQIYTAYVSWGLDGKRRPVLIVEDKNKNVFCYRITSKYKNKS
                     ERIKKNYFPLMDWKIEGLDKQSYVDVGDIIKLSKEHVSFRLIGELSTHDIEALVEFIRN
                     RYEI"
     CDS             complement(5001..7160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 280.9; E-value:
                     3.6e-85)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_12"
                     /sec_met_domain="TIGR01193 (E-value: 1e-288, bitscore:
                     952.2, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-38, bitscore:
                     124.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYNFRRHYINQVDEADCGVAALAMILHNYGSKISLATLRKFTKTT
                     TDGTTALGIVKAAEKLKMDVEAYQADASLFDSKDVIYPFIAHLIKKDSGLLHYCVVFKS
                     SKKHIFIADPDPNIQVKRIPKVNFFEEWTGIAIFAKPGKNYKPIQEKIPTFKRLCRPLF
                     QQKALLFGIITAAFIVTFLNILNSYYLQTLLDTLIPNKLQDPLAIISIGLLFAYLFNSL
                     FTFSRDYLLAILGQKLSKIIILNYIKHVLRLPMAFFSTRKTGDILSRFTDANKVIDALV
                     SAIISIFLDATILIIIGTVLALQDIRLFGITMLIIPIYSLIIFSFTSNFRKLNQKEMES
                     NATVSASIIEDIRGIETIKSLNCEEVRSNKITNEFNDFLHKSLVHTRLNNIQQGLKTFV
                     QLSLNLIILWVGANQVIKNELSIGQLMTYNALLIYFTTSLQNIINLQPKIKSAQVANSR
                     LNEIYMVKDEFENTTKHNHSLKNGTIELKNVSYSYEYNSPILQNINLKIKSGEKLTIVG
                     LSGSGKSTLMKLLVNYFDVSNGEILINNLNILNISKKQLRSFINYVPQIPYTFSGTIKE
                     NLLLGNRTTITEKDIVTACKTAMIHDDIMHLPLGYNSKLDENATTFSGGQKQRLTIARA
                     LLSPAKVLIFDESTSGLDVLTEEKLIKNLMALSSKTIIFIAHRLSIAQITNNITVIDNG
                     KIVEQGSHEELLKNKSLYFKLMQTQ"
     CDS             complement(7172..7945)
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MDYHLLVCDDDRTQAKNIATLLKMSSIILEEQDIHPTIDLIATDA
                     ESVLDYLEFNSDLNNIIAFLDIQLDENSNSKGGLDLAQKIKTLSEKAQIIFITTHEELA
                     FLTFQRRINPLDYITKTTNQRDLQRRLTETLELAIRKLNEFNYIKKNTFSYKVGTRIIN
                     VNFSNILYISTTKFPHKLKIVTSNGQGEFSGDIKTIEQNYPLFFKASQSSLINLQNVET
                     INTKKRLIKFSNNDCLNYSRSRAKELNNLYKNLTC"
     CDS             complement(7958..9220)
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="LSIPIQIFAATISILFDYIFFFLLIKIRPTKYDICPLLIIFIIVF
                     FINGLGYIGSYLVPFFEGSFLYLNYKRRASNKKLLGALLITFITSILIAFLAFVIGKLF
                     LLSTNQRLGINLIFSITILIFFFYYNPIKKIQEGNETLNLWILFYLLVSLIIVGFITFT
                     TTEVTPAFIVIFCLLVLQCSFTVFIYRISKQIQQKKLQLQEKKDLLFLIQNLEENQLKL
                     RRFKHDYQNLLNSLKLSAIHGDNQALLDKLENYSRDNLGKDSLWQFQDTKNIKDDVLRS
                     IFISKLNSIYQKDIKYHFECLTEINDLPNIDLFDLIRIIGIAYDNALEECETLKKLGAR
                     TVEINSMLYQSAPNKLEFEIKNTCRKQLSTNKLHQEGITNKTNHEGLGLATAQKISNKY
                     HNVYIAYSSNNGYFTFTISIE"
     CDS             complement(9240..9359)
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MKKLSTQQLSLIKGGAIPGINYTDHSSYASWMLKKLIKH"
     CDS             complement(9575..10057)
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MNKLFQWFYNMPKLTNQDNKDYMAKISLNIAVSLFLFNLVAVLIS
                     FFIVTTTENYELSFNILAGALLIFTVYIVGGYSICAKRKINRVVTHDNTHIVKNSFASA
                     VYITLIIYLLNSLTNALSFHTSLISELKNPMSYIIPTVIGIIYGTLMAIITWYRGK"
     CDS             10260..10466
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_17"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3e-16, bitscore:
                     52.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLDNSQLKMILGGKNSWQQNVWGVARSTAAGAGLGAAICGPGC
                     AFVGAHYGAIVWAGTTGATHGFH"
     CDS             10493..10681
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_18"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4e-10, bitscore:
                     32.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLKYNQLELIIGGNRWGNATIGAMNGAKYGVKLCRPGGPWAMG
                     GCGLVGAGIGGYVGYRF"
     CDS             11034..11342
                     /locus_tag="ctg18_19"
                     /transl_table=11
                     /translation="MILINFLKKNKWNIIAILIFFIICVYYAYNKNIVASTSSLLCAIL
                     WLIDCLKKQYFFLEGIAIILYAIFILIIRIDLWPGALACIVIGLFILFFYLKKLKKQ"
     CDS             complement(11678..12607)
                     /locus_tag="ctg18_20"
                     /transl_table=11
                     /translation="MSIGQIFNQVVIIFLLMLLGAVIRKLGFLHPQSINDLTNITLYFL
                     SPIVIIKAFEQPFSRSRFYQLLLLIAGVFLTYFVSILIAKLLFHKVKDQNIRQIATYGS
                     IYSNNGFMGVPLAQGLFGSVGVFYAVASMIGFNVMSWTQGIGIFQKRQPHDWRTQLKKI
                     ILNPNIIAIIIGLFLFISSFRLPKLISGFIDYTSPAFTPLSMIVIGSNLANLNIKNIKL
                     PTVLWGSLFVRNIFFPILGTIILLLLGITGVPLFTTVILSACPVAGLVVLFTLQSNGDA
                     RPATVLMSISTILSLVTIPLVYWFASLW"
     CDS             12887..13567
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 213.1; E-value: 6.1e-65)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg18_21"
                     /transl_table=11
                     /translation="MKKAVIMLVEDEESLASFLITELELEGYEVIWAKDGREALEIFKE
                     KDITLILLDWMLPVYDGLTVLRRIRQSSNVPIIMITARSQTSDISMALDQGLDDYITKP
                     FEIEELLARIRVVLRRLGQKKAEKYDYKFRPFEINLLKHQFMVDGKRVHLTPKEFSLMV
                     ALIKEPGVVQTRDDLLNEIWGYDFDGQTNTVDVYIRALRNKLGKYRDLIKTVRGIGYVL
                     GDEQ"
     CDS             13564..14895
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 188.6; E-value: 4.4e-57)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg18_22"
                     /transl_table=11
                     /translation="MSNTHPVTASRQLTRLFLMLFTVILVVINLLFVVTATNLIYRYAD
                     DQAEEVIETIEEDWPENQNRETFLNAYVARQDDDAIEITDGKREYTSPKAHKIFKRIDQ
                     RNLAIKNLQLTQHGVYYLRQQKIDHNRIVKVAINVDDLIKLTGWLLIVTLLINLAISII
                     ALPIIHRLARRWTRPLTNLDNEIDAITPQSNRLQTLTVPQQPLEVRKVAQSFNHLLGRQ
                     YRTMQREKEFIANASHELKTPLAGILGHVNLIRRHGDKHPELIAKSLKYIDQEAQRMSQ
                     LINELLILEGHQTKKLTEINLSKIIFAEVESLQGAYHQKFIADLNPNISYRITKGDFQS
                     LVHNLLENAAKYSPPDSTINVQLTADDHQIILRVADQGRGIAKENREKVFERFYREDES
                     HSNKIAGSGIGLAIVKMIIEKYHGKITIRDNEPSGTIFTVYLPK"
     CDS             15000..15650
                     /locus_tag="ctg18_23"
                     /transl_table=11
                     /translation="MTEKIEKRQDQQPKPDKKKARKFPKMTKKVLITACVCGGLVLGAG
                     GIAGVAAMDGYHAQIEAAVKHEKLANKSDIKINQQAAIDQFNKKYPDKHLNEVELESDK
                     GKYVYKVKGFDNTNEYKVKANAKDGKLISNKSEKLDQNEKEYTLDPGKAISRDEASQIA
                     EKAAKKGSAIEWKLEQEKENQAVWEVKVKDGRTVKEVKIDAGSKKVLAVENNH"
ORIGIN
        1 taagtgcatg caaatcatca gtgtttcctt ctaactggat aaagcaagag aatcctttac
       61 tttgcttgag tgcaaattga tccagatatt ttccaagcac ttctgctaag aggacacaac
      121 aagtaccgat aaccccgatg ctatataaac cactaccata agcaaggccg attgcaccag
      181 taacccagat ccctgctgcg gttgttaaac catcaattat ttgatcatga cgattaataa
      241 ttgttccagc acccaaaaaa ccaattccgc taacaacttg agctgcaatc cgcgatgggt
      301 caacattcca attactatga gtaatcttca ttaaatcgaa aaaaccatat tttgaaataa
      361 tcatgaccat tgctgccccc acggcaatta gggcatgcgt tcgaattcca gccattttag
      421 ccttgctttt tcgctcaaaa ccaatgatcc caccacataa ggcagccatg agcattcgta
      481 aacaccagtc aagcctaagc aacgattacc cctcctttac caaaaatcaa ttattatcaa
      541 ttttattaac ctaactgtac tatatcgcgt ttaggtgttt aaagccaaaa agaaagctga
      601 acgaaataaa aatttccttc agctttttaa ctatttctca tatacagaac gctttagcac
      661 gcccacatat ggaagattgc ggtagagacc atcaaagtct aagccgtatc caacaataaa
      721 ttcattggga actttaaagc caacataatc ggcttcaaca tcaacttcac gccggtctgg
      781 cttatcgagt aaggagcaaa tctcaatact cttcgcgcca cgattagcaa aaagagcaac
      841 gagatacttt aatgtatgac cagtatcaat aatgtcttcc ataataagaa ctggccgatc
      901 cttaatatca tgggaaagat cttgaattaa tttaactttt ccggtggatt ctgaactttc
      961 ttcataacta gaaacgtcga cataatcaac gtttaacttg aaattaaggc gcttcatcat
     1021 ttcgctagtg aaaatcattg ctcctgtcat tacggaaact aaaactggaa atttaccttg
     1081 gtatttttca gtaagggtat tggcaagttc atctaagcgt tggttgactt gatcttgagt
     1141 atataaaact ttttcgacgt cgttattcat tctagctctc ccttgataat gttcgttatt
     1201 tacgaactat ttttgcggtt tttatttatt gacgttagaa ttttaacata aatcgaatga
     1261 atttaaagtg ttttagcaag aaaaatcata tttttgttct gctttgtaag atgaggcata
     1321 aaatttgtat aatacaggta gatatttttt gaaaacggat gcctggaagg gatgcttata
     1381 attatgaaaa aagttaactt atatattttt ttgacgcttt gttcctttgc catcttctta
     1441 ttgaccacgc catcaaaggt aaaggcagaa gtagttgaca aacaaacgca acaccaactt
     1501 caagattata tgaaggacca tcatattaat ggagtgatgc tagttaatgg caaagatggg
     1561 aagccagttg ccattgagaa tcatgaaacc acgaataagg atcaaatcgt aaaggcggat
     1621 cgactatttc ccacggcatc gcttcaaaag attgtaacgg gaaccgctgt ttaccaatta
     1681 aggcaaaaaa agcaattagc ttgggacact tcgctaagta agtattatca gcagattgac
     1741 ggtagtaaag atattacgat tcgggaatta atgaatcata ccagtggctt gattaataat
     1801 gatcgtccct tcgaaccact tagaggtcaa aaagcacaaa ttgcttatat gcttaaacat
     1861 ctcaagtatg atcatacgca cacgtgggat tatcaggatg ttgattatga aatcttggca
     1921 gcgattgtta gtaagcaaac gcatcaaagc tataatgact atattcgaaa aaactttgct
     1981 aaaccgctcc atcttcacca aattaaagat ttttctgagg tttccaaaaa agaaattccg
     2041 caaccaatgg atccaacagt tgattggcac cgggtaactg taacgacctc ctcagatttt
     2101 ggagcgggga acttatttat atcaccaaac gattattgga agtttgtata taatgaggtc
     2161 ctgaaagatc caaaaatgat taatgaatat tatcatcaag cccagcatca agaagtggcc
     2221 tattttggtg gggtctactt tgatggggat gtaatccggg ccaacgggag tattccgggc
     2281 tacaacagtt gctttgtcgc cgattacaag acgaaacgaa tgattatgct gttctctaat
     2341 aatatcgatt atctaaaatt aaaggcagct tcggatgata ttctccataa ctatatggaa
     2401 taacgataaa tgccttctga gtaaacaaat gagttttgct cagaaggcat ttttagatat
     2461 tagtataatt ttatgggttg cttgctaagg ctaaaatccg ctgcttaatc tcattgcgta
     2521 cttgccggaa aatttgcaac tgctgttcag gagttccggt ggcttgtgct ggatctggca
     2581 gaggccagta gatactgtgc gttggaggag cgatgactgg gcaacggtct ttggagtctc
     2641 cgcataaggt tacaattaaa ttggcggtct taaaataatg aggatcaatc gttttagaat
     2701 attggtgact aatatcgata ttgtcttctg ccattacctc aattgctagg gggttaacgc
     2761 catgagcttc aagaccagca ctttggattt cgtacttgtt tttcagaaaa attcttgcat
     2821 atccttccgc catttgactg cgacaagaat tgccagtaca taagaaataa attttattca
     2881 ttttagtaat atctcctggg ataaaattag gatcaagtag gctgagggac tagagagaag
     2941 cagaattact gatataataa catgaaaaag ttaggaattt aagttgaaaa ctagtaaaag
     3001 tgaacacgag cttaaaatag acttatatat tgcttgttac ttattcctaa taggtacgtt
     3061 atgtcacaat gtaatttcct gacggaggat caccttatat ctgaaggtgg ctctgttttt
     3121 tacttgaact tatttgctat tagtgagaac attacaagac aaaaaaactc ccccccaaaa
     3181 aaaagaggga gctaatcgcg ataagtaatc gactggtggt tacaaatcaa taatttctgg
     3241 ttcaaaatca atcggcttga gaaatttaaa catgtcatct gttttaataa aaattgtatg
     3301 agtattttca ttgggatgga aagtctgaat tggttcgtcg acaatgtcct tgtcaaaata
     3361 tacctttaca ttatgagctt cattatttag gaggccaaat ggtgaaacaa ttcctggtgc
     3421 taagccaagc tgttcttgca gatattccgg tcgagccatt gaaacccttt tagctccagt
     3481 tagggccata aattcatgaa agtccattgg ttttttatca tccataataa ccatatagaa
     3541 attctttttc ttccctttca gaaacatggt tttagtgcga acaccttcat gaccagcgat
     3601 atatgcatca gcttcttcgg tggtgtgagt agcagggtga tcaatcacag tataatcagt
     3661 tattccgaaa ttctttaggg catctttaac ttgctgatag gttcctaatg ccataatttc
     3721 gctccttaat taaatttttt gtcatgaaac gcttacatta attataaagc aaattaagca
     3781 attaaatgag ccaatatttt ttctgtaaaa cttgtttcaa ttaatgctag ggatcgaact
     3841 taatattttt tatggaagaa attttaattg aagcctttgt tgcttattag gaaatgtcat
     3901 gatgattctt atattttata atcacaatat gttatcatat gatcgtgagg tgattacaat
     3961 gagttcgaaa gttcaagtaa acattgatcc agaattaaaa cagtcagcgg agaatattat
     4021 aaaggaaatt ggtttaaccc cgacagctgt aataaatgga atgtataaac aaatagttgc
     4081 cacagggaaa atccctctta gtttttcttt gacaccaaaa caaaggacgg aattggagtt
     4141 aagagaagta tccaagaaaa ttccagttcg agaagttaaa acaaaagagg aacttgagga
     4201 attttttaat gaggactaat caaatttata ctgcttatgt atcttgggga ttagatggga
     4261 aaaggcgtcc agttttgatc gtagaagata aaaataaaaa tgtcttttgt tatagaataa
     4321 caagtaaata caaaaacaaa tctgagagaa ttaagaaaaa ttattttcct cttatggatt
     4381 ggaaaataga agggcttgat aagcagtcat atgttgatgt gggagatatt attaagcttt
     4441 caaaagaaca tgtgtctttt agacttattg gagaattgtc aacgcacgat attgaagcgc
     4501 tggtagaatt tattcgcaat cgatatgaga tatagaaaca aaaacgtcgc agaaaaaatt
     4561 ctgtggcgtt ttgttttgca acttgcgagg aaattaaagc gtaaacgcat agagtcacag
     4621 taaattacca cgaccctatg cgttcaagtt tcagttaact gtaaccagac cactccatcg
     4681 ctttagtcag gtcgattcga tctttcccag ttgcgatcca agaaatattt tgacgattgc
     4741 ggtaatcaag gtaatctttt gtaacttgtt cactcgtaat aatttagata aaaaagcctc
     4801 ttttgcctta agatgtaggt gttcgagcca aagtcaataa gggaaaagag gtaataagaa
     4861 tatgactaat aattaaacaa gttagtcata taaaaagtat aaacggaaaa ttatatagtc
     4921 aatattaaaa gattatatgg ctattgtata agctaaggag gcttaatctt tatgcaaaat
     4981 tgaataaaaa tagtctctat ttattgtgtt tgcataagtt taaaatataa cgatttattt
     5041 ttgaggagtt cttcatgaga accctgttca acaattttgc cattatcaat aactgtaata
     5101 ttatttgtaa tttgagctat tgaaagacga tgggcaataa agatgatcgt ttttgaagat
     5161 aatgccatga gatttttgat tagtttctct tctgttagaa catcaagtcc actagtagat
     5221 tcatcgaaaa tgagtacttt tgctggtgag agtaatgctc tcgctattgt aagtcgctgc
     5281 ttctgccctc cagaaaaagt tgttgcattt tcatctaatt tactattata tcccaacggt
     5341 aaatgcatta tatcatcatg tatcatagcg gttttacatg cagttacaat atctttttca
     5401 gtaatcgtag tgcggtttcc taataataag ttttctttaa tcgttcctga aaatgtataa
     5461 ggaatttgtg gcacataatt aataaaagaa cgtaactgct ttttagagat atttaaaata
     5521 tttagattat taataagaat ttcaccattt gaaacatcaa aataatttac taataatttc
     5581 atcaaggttg atttaccaga gccacttagc cccacgattg tcagtttttc gccagactta
     5641 atttttaagt taatattttg taatatagga gaattgtact cgtaactata agaaacattt
     5701 tttaactcga ttgttccatt ttttaatgaa tgattatgtt tagttgtatt ttcaaattcg
     5761 tctttaacca tgtatatctc atttaaacga ctattagcaa cttgcgcact tttgattttg
     5821 ggttgtaggt taatgatgtt ttgaagggaa gttgtaaagt aaattagtaa tgcattatag
     5881 gtcattaatt gcccaattga taattcattt ttaataacct ggttagctcc aacccataaa
     5941 atgataaggt taagcgaaag ttgaacaaaa gttttgagtc cttgttgtat attatttaat
     6001 ctagtgtgga ctaatgactt atgtaagaaa tcattaaatt cgttagtaat cttgttagaa
     6061 cgaacttctt cgcaattaag agatttaata gtttcgattc ctctaatatc ttctataatt
     6121 gatgcactta ctgttgcgtt actttccatt tctttttggt ttagtttcct aaaattacta
     6181 gtaaatgaaa aaattatcag agaataaata ggaataataa gcatagtaat tccgaataat
     6241 ctaatatcct gtaaagcaag aactgtgcct ataattatta aaatagtggc atctaaaaag
     6301 atagatataa ttgcactgac aagagcatca attactttat tcgcgtcagt aaaacgagat
     6361 agaatatcac cagtctttct agtagagaaa aatgccattg gaagtcttaa aacatgcttt
     6421 atatagttta ggataataat tttagatagt ttctgcccta gaattgctaa taagtaatcc
     6481 cgagaaaaag taaatagaga gttaaaaaga taggcgaaca atagtccaat actaataatt
     6541 gctaaaggat cttgaagttt attaggaatt aatgtgtcaa gtaaagtttg tagataataa
     6601 gaatttaaaa tattaagaaa cgttacaata aaagctgctg taataattcc aaaaagtagg
     6661 gctttttgtt gaaaaagtgg tcgacataat cttttaaaag tggggatttt ttcctgaata
     6721 ggtttatagt tcttacctgg ttttgcaaaa atagcaattc cggtccattc ttcaaaaaaa
     6781 ttgaccttag gaatacgttt aacttgtata ttaggatcag gatcagcaat aaaaatatgt
     6841 tttttggaac ttttaaaaac aacacaatag tgaagtaggc cactgtcttt ttttatgaga
     6901 tgagcaataa aaggataaat tacatctttt gaatcaaata aactagcatc tgcttgatat
     6961 gcttcaacat ccatttttaa cttttctgct gcttttacaa tcccaagtgc agtagttcca
     7021 tcagtagtgg tttttgtaaa ttttcgcaga gttgctaatg aaattttaga gccgtaatta
     7081 tgaagaatca ttgctagtgc tgctactcca caatcagctt catccacttg atttatatag
     7141 tgtcttctaa agttatacat aaagtgcctc gttaacaagt tagattttta tatagattat
     7201 ttaattcttt agctctgctt ctagaataat ttaaacaatc attgttggaa aacttaataa
     7261 gccgtttttt ggtattaatt gtttcaacat tttgtaagtt aattaagcta gactgcgaag
     7321 ctttgaaaaa tagaggatag ttttgttcaa ttgttttaat atcacctgag aattcccctt
     7381 gaccgttaga tgtaacaatc tttaatttat gagggaattt tgtagtagag atataaagga
     7441 tattactgaa gtttacattt ataatccttg taccaacttt ataactgaat gtattttttt
     7501 taatatagtt aaattcattc agtttcctta tagctagttc tagggtttcg gttagtcgtc
     7561 tttgtaaatc tcgttggttt gtagttttag ttatatagtc caacggatta attcgccgtt
     7621 gaaaggtgag aaaagctagt tcttcatgcg ttgtaataaa gattatttgt gctttttcgc
     7681 taagtgtttt tatcttttga gctaaatcta gaccgccttt tgaattagaa ttttcatcta
     7741 actgaatatc taaaaaggca ataatattat ttaaatcact attaaactca aggtaatcta
     7801 atacactctc tgcgtcggtt gcaatcaaat caatggtcgg atgaatatct tgttcttcaa
     7861 gaataattga tgacatttta agtagtgtag cgatattttt tgcttgagtc ctgtcatcat
     7921 cgcagacaag taaatggtag tccataagta ttcctttcta ttcaattgaa attgtaaatg
     7981 taaagtaacc attattggag gagtaagcaa tatatacgtt gtggtatttg ttagatattt
     8041 tttgagctgt tgctaatcca agtccctcat ggttagtctt atttgtaatt ccttcttgat
     8101 gaagcttatt ggtgctaagc tgctttcgac aagtattctt aatttcaaat tctaacttgt
     8161 taggggcact ttgatacagc attgaattga tttctacagt acgtgctcct aactttttta
     8221 aggtttcgca ttcttcaagg gcattatcat aagcgattcc aattattcga attaaatcaa
     8281 ataaatcgat atttgggaga tcattaattt cagttaaaca ttcaaaatga tatttaatat
     8341 ctttttggta aattgaattt aatttactaa taaagatact tcgcaagaca tcatctttaa
     8401 tgtttttagt gtcttggaat tgccaaagag aatctttacc aaggttatct cgagaatagt
     8461 tttctaattt atcgagtaag gcttgattat caccatggat ggcacttaat ttgaggctat
     8521 ttagtaagtt ttgataatca tgtttaaatc gtcttaactt caattgattt tcttctaggt
     8581 tttgaatgag gaataataag tctttctttt cttgaagctg gagctttttt tgctgaattt
     8641 gtttactaat tcgatatata aagactgtaa aactgcattg aagaactagt aagcaaaaga
     8701 taacaataaa ggctggcgtt acttccgttg ttgtgaaagt tataaagcct acaatgatta
     8761 ggctgacaag aaggtaaaat aaaatccata aattaagagt ttcattacct tcctgaattt
     8821 ttttaattgg attgtagtag aaaaagaaaa ttaaaatggt tattgagaat attaaattga
     8881 ttccaagacg ttgattagtt gatagaagga ataatttacc gataacaaat gctaaaaaag
     8941 caatcaatat agatgtgata aaagttatta aaagagcacc tagcaatttt ttgttggatg
     9001 cccttcgttt gtaatttaaa tatagaaaac tgccctcaaa gaatggtact aaatacgatc
     9061 caatatagcc tagtccgtta ataaagaaca caataataaa tattatgagc aaggggcaga
     9121 tatcatattt tgtcggtctt atttttataa gtaggaaaaa gaaaatataa tcaaacagta
     9181 ttgatattgt tgcagcaaaa atttgaattg gaatagacaa tgtataacct cttataagat
     9241 tagtgcttta ttaatttctt aagcatccaa ctggcataac tactatggtc agtataatta
     9301 ataccgggta tagcaccacc tttaattaaa gatagttgct gagttgatag ttttttcata
     9361 aataaatctc tcctattgtt ttatcagtaa tttattttaa caggatgcat caaaaaaatc
     9421 ataaataatc aaaagtagtt gtttaaggtt caaatcctgt aagaaatgag tccgattatt
     9481 ctgttagtaa aaaataataa atgttaaatt tttgtttaac ttctcaataa ggaaattgct
     9541 ttcagttaat cttccttaat taaaaacata cttattattt gcccctatac catgtaataa
     9601 tagccataag cgtcccatat ataatcccaa ttacagttgg gattatataa ctcatgggat
     9661 tttttaattc gctaatgagt gaagtatgaa aactaagagc atttgtaaga gaattaagta
     9721 aataaataat cagtgttata tatacagctg aggcaaaact attctttaca atatgtgtgt
     9781 tatcgtgagt cacgactcta ttaattttac gttttgcaca tatagaatag ccaccaacaa
     9841 tataaacagt aaaaatcagt aacgccccag ctaaaatatt aaaagacaat tcataatttt
     9901 ctgttgtagt aacaatgaaa aaggaaataa ggacagcaac gaggttaaaa agaaataagc
     9961 taacagcgat attaagacta atcttcgcca tataatcttt attatcttga tttgttaatt
    10021 tgggcatatt atagaaccat tgaaaaagtt tattcattaa tttattcctt ttaaaaagtt
    10081 tggtttttac catagcataa tttatctttt ttaataattt tcttctaatt ttagtggaat
    10141 tttagcatat taggatgttg aagcaggata tgagtgtaat ttgtacaaat tagaagtttc
    10201 catttagcag tcttaattta ctttatgctt aaagtataga aattaaggag gtaattgtta
    10261 tgaaaaaatt agataattca caattaaaaa tgattttagg tggtaaaaat tcctggcaac
    10321 aaaacgtctg gggagttgcg cgttctacag cagcaggtgc agggcttggt gcagctatct
    10381 gtggcccagg ttgtgcattt gttggggcac attatggtgc tattgtttgg gcagggacta
    10441 ctggtgctac ccatggcttt cactaaaaat taagaatacg aggagaattg taatgaaaca
    10501 attaaaatac aaccaattag aacttattat cggcgggaat cgttggggaa atgcaacaat
    10561 cggcgcaatg aatggtgcca aatatggagt gaaactttgc cgtcctggtg gtccatgggc
    10621 catgggagga tgtggtcttg ttggtgctgg catcggcggc tatgttggat atcgtttcta
    10681 aaataggagg aattctttat aaaaaaattt ttgtttgatc cattatattt ttttgctgta
    10741 gcttttatgt atttaatatt tgattacaat tttggcatga tatcgatgtc aatcttttgt
    10801 ggactttcat tattaattag taatctagga aagaaatttt tatatttgca agcactattg
    10861 ttcataatat atggattatt actttttata gttcatccaa gcacatggat agtttctgta
    10921 attttgatct taattggaat agtcttcttt atattttatt ttagaggatg aactggcttt
    10981 tagaatagtt agagtcggag gaaaaattgt ttcgactatc atgtggagtt ttaatgattt
    11041 tgattaattt tttgaaaaag aataagtgga atataattgc aatattaata tttttcatta
    11101 tttgtgtata ctatgcatac aataagaata ttgttgcttc tacatcttct ttactttgtg
    11161 caatcttatg gctgattgat tgtttaaaga aacaatattt tttcttagaa ggaatagcaa
    11221 taatcttata tgctatattt attttgatca ttcgaataga tttatggcca ggtgcattgg
    11281 cgtgtatagt aataggattg tttatcttgt ttttctatct aaagaaactt aaaaagcaat
    11341 aatctggaga ataaaagtta tgatcccagt tggatactgg aatcatacct ttttatcttg
    11401 cacttcaact ttataaattt cattacgcaa gccccttcgc tactttggtt taaataccca
    11461 aagtgtgtgc gagagttctt gcgttttctt gtttttaaag cacaaacgca tagaatcaca
    11521 gtaatttaac ccgatcctat gaatttaatt ttcaattgta atatatggtt tattcattta
    11581 taaagcctcc acgtatctaa ttccatcata gattaaggag gctattattt gaaatgctta
    11641 ttatatttaa tactttattc aaagattgta tatatcatta ccatagacta gcaaaccaat
    11701 agactaatgg aatagttact aaactcaaaa tggttgaaat actcattaag acggttgctg
    11761 gccgtgcatc tccatttgat tgtaaggtaa aaagaacgac taatcctgct accggacatg
    11821 cactaagaat tactgtggtg aagagtggaa caccagtaat tcccaataat aataagataa
    11881 ttgtccctag aatcgggaag aaaatattcc ttacgaagag acttccccag agtacagttg
    11941 gtaatttgat atttttaata tttaggttgg caagattact tccgatgaca atcattgata
    12001 gtggagtaaa cgctggactg gtgtaatcaa taaaaccaga aattaatttt ggcaaccgaa
    12061 aagaactaat gaataggaaa agaccaataa taatagcaat aatattagga tttaaaataa
    12121 ttttctttaa ctgtgttctc caatcatgag gctgccgttt ttgaaaaatt ccaattccct
    12181 gggtccacga catgacatta aaaccaatca ttgaagcgac agcatagaag acacccacac
    12241 ttccgaaaag tccttgtgct aatggaacgc ccataaaacc attgttagaa tagatgcttc
    12301 cataagttgc aatctgacga atattttggt cctttacttt atgaaaaagt agttttgcaa
    12361 tcaaaatgga aacaaaatag gtcagaaaga caccagcaat taatagtaat aattgataaa
    12421 atcgtgatcg cgaaaacggc tgttcaaagg ccttaataat tacgattggc gataaaaagt
    12481 agagagtaat atttgttagg tcattaattg attgtggatg gagaaatccg agctttctaa
    12541 taactgcccc taaaagcatt aataagaaaa taatgacgac ctggttaaaa atttgcccaa
    12601 tcgacattgc accacttcct tcagttaaaa atcacaatta ctattttata acaaaaagga
    12661 gaatgatttt actgaaggtg ccgacgctca ttgcgatcaa cggcaaaagg ttcttaataa
    12721 tgtattaaca ggagcggaat cgatggcgaa attattttga tataatggcc ttaatgaata
    12781 agaagaaaaa agtttcatat gaaacttttt cgtttacctt taaccaccat ttaaaaacat
    12841 aaaacagcta aaatagaaga taagaaaatc gcttggaggc aaaataatga agaaagctgt
    12901 aattatgtta gttgaggatg aggaaagtct tgcaagtttc ttaataactg aattagaact
    12961 agaaggatat gaagttatct gggccaaaga tgggcgtgag gcactcgaga tatttaaaga
    13021 aaaagatata accttaatct tattagattg gatgctccca gtttatgatg gtctcacagt
    13081 tctacgccga attcggcaat caagtaatgt gccaattatt atgattacgg ctcgtagtca
    13141 aacttctgat attagtatgg cacttgatca aggattagat gattatatta ctaaaccgtt
    13201 tgagattgag gaacttttag cacgaattag ggttgtatta cgacgattgg gtcaaaaaaa
    13261 agcagagaaa tatgattata aatttagacc atttgaaatt aatttactga aacatcaatt
    13321 tatggttgat ggcaagcggg ttcatttaac gcctaaagaa ttttccctca tggttgccct
    13381 aattaaagaa ccaggagtcg ttcaaacccg tgatgacctt cttaatgaaa tatgggggta
    13441 tgattttgat ggtcagacca atactgttga tgtctatatt cgtgctttgc gcaacaagtt
    13501 aggcaaatac cgcgacttaa ttaaaacggt gcgagggatt ggttatgtat taggtgatga
    13561 gcaatgagta acacacatcc agtaactgca tcgcggcaat taactcgtct tttcttaatg
    13621 ttgtttacag tgattttagt agttattaat cttctttttg tggttaccgc cactaattta
    13681 atctatcgtt atgctgatga tcaggcagaa gaagtgattg agacaattga ggaagattgg
    13741 cccgaaaatc aaaatcgcga aacttttttg aatgcttatg ttgctcgtca agacgatgac
    13801 gcaatcgaga tcactgatgg taaacgagaa tatacctcac ccaaagccca taaaattttt
    13861 aaacgaattg accagcgaaa tttagcaatc aagaatctac agttaaccca gcatggagtc
    13921 tattatttac ggcagcaaaa aatagaccat aatcgaatcg tcaaagtagc aattaatgtt
    13981 gatgatttaa tcaaattaac aggctggctc ttgatagtga cgctgttaat taaccttgca
    14041 ataagtatca ttgctctccc catcattcat cgtttagctc gccgatggac ccgaccattg
    14101 actaatttag ataatgaaat tgatgcaatc acgccccaaa gcaatcgatt gcaaacttta
    14161 acggttccgc aacaaccatt agaggtacga aaagttgccc agtcttttaa tcatttgcta
    14221 ggacggcaat atcgtacaat gcaacgcgaa aaagaattta ttgcaaatgc atctcatgag
    14281 ttgaagacac cacttgctgg aattttagga catgtaaacc taataagaag gcatggggat
    14341 aagcatccgg aattaattgc taagtcatta aagtacattg atcaagaagc acagcgaatg
    14401 agtcagttaa taaatgaact gcttattcta gaaggacatc agactaaaaa actaacagaa
    14461 attaacttgt caaaaattat tttcgctgaa gttgagtcac tccaaggtgc atatcatcag
    14521 aaatttattg ctgacttaaa tccgaatata tcttaccgca taacaaaggg tgactttcaa
    14581 agtcttgttc ataatctctt agaaaacgcg gccaaatatt cacctcctga ttcaacgatt
    14641 aatgtccaat taacggcgga tgatcaccaa ataatattaa gagttgccga tcaagggcgg
    14701 ggaattgcta aggaaaatcg ggaaaaagtt ttcgaaagat tttaccgtga agatgaatca
    14761 cactccaata agattgctgg ttcagggatt ggcctggcga ttgtcaaaat gattatcgaa
    14821 aaataccacg gaaaaatcac gatacgcgat aatgaaccaa gtgggaccat ttttacggtt
    14881 taccttccaa aataaaaatg aagatttctt catcatactt tcaccggttc ttggttttag
    14941 ttgaccgatt attttgtaga ataaaattac caattaaagt taagaaggga tgaataaaaa
    15001 tgactgaaaa aattgaaaaa agacaagacc aacaaccaaa gcccgacaag aagaaagcaa
    15061 ggaagttccc aaagatgact aaaaaggttc tgattaccgc ctgtgtttgt ggaggacttg
    15121 tgttaggagc tggaggcatt gctggtgtcg ccgcaatgga tggttatcat gctcaaatcg
    15181 aagccgcggt gaaacatgaa aagttagcta ataagagcga catcaagatt aaccaacagg
    15241 ctgcaattga tcagtttaac aagaagtacc cagataagca cctcaatgaa gtagaactgg
    15301 aaagtgacaa gggaaaatat gtgtacaagg taaagggctt tgacaatacc aacgaataca
    15361 aggttaaagc caatgccaag gatggcaaac taatctctaa caagtctgaa aagcttgacc
    15421 aaaatgagaa ggaatatacc ttagatccag gtaaggcaat tagccgtgat gaagcgagcc
    15481 aaattgccga aaaagccgct aaaaagggta gtgcgatcga atggaaatta gaacaagaaa
    15541 aggaaaatca agctgtttgg gaagttaaag taaaagatgg ccggacagtt aaagaagtta
    15601 agattgatgc cggttcgaaa aaagtattag ccgtggaaaa caaccattaa tttatccata
    15661 atttgcgcat tcatccccca c
//
