LOCUS       c00010_JAJGTH0..       12082 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGTH010000146.1 Limosilactobacillus reuteri strain M_2
            scaffold146, whole genome shotgun sequence.
ACCESSION   JAJGTH010000146
VERSION     JAJGTH010000146
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 10:46:10
            Original ID  :: JAJGTH010000146.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 64872
            Orig. end    :: 76954
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12082
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[69872:71954](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7082)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12082
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12082
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1952..3139
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     2.1e-73. Score: 239.3. Matches aSDomain:
                     nrpspksdomains_ctg10_49_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 272.8; E-value:
                     7.9e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_49"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.5e-07,
                     bitscore: 22.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFAKLTPGGIREFDYQVSAIPGIIKLTLGEP
                     DFNVPAAMKQAAIDSINANDSHYAPGNGTLALRQAIAHFMQDRYELEYDPENEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYIAVTKILGGIPIEVDTSSDDFVLTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALANTVKSTNLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGFELINPQGAFYVFVKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIAAFINKED"
     aSDomain        2060..3112
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg10_49_Aminotran_1_2.1"
                     /evalue="2.10E-73"
                     /label="ctg10_49_Aminotran_1_2.1"
                     /locus_tag="ctg10_49"
                     /protein_end="387"
                     /protein_start="36"
                     /score="239.3"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPAAMKQAAIDSINANDSHYAPGNGTLALRQAI
                     AHFMQDRYELEYDPENEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYIAVTKIL
                     GGIPIEVDTSSDDFVLTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALANTV
                     KSTNLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGF
                     ELINPQGAFYVFVKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             3141..4136
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 294.6; E-value: 1.1e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_50"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTANV
                     DGLVIQQRSKVPADIYEKLHTNRLKQITTRTAGFDMVDIKKANENGLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSIEIHTARIGIIGVGRIGGTLAKL
                     LNALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPTSKGLLTANDFAM
                     MKPTAGLVNASRGPVVNTADLVTALKAGEIAAAALDTFEGEEAVAAADRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMTILNGRKSPHEITL"
     CDS             4204..4632
                     /locus_tag="ctg10_51"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSN
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             4783..4968
                     /locus_tag="ctg10_52"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYIYLLLLFLWIAPFSDGSLPLDEELLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(5001..7082)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 313.2; E-value:
                     5.9e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_53"
                     /sec_met_domain="TIGR01193 (E-value: 5.7e-264, bitscore:
                     870.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 6.1e-30, bitscore:
                     96.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILHNFGSVYPIAKLRDLARTTKQGTTALGLVKAAKHLGLDVIPI
                     QADISLFDDPEITYPLIAHVIKDDLLHYCVVFKADQDYIYVADPDPATKVQKITRDEFD
                     RLWSGVCLLFSPAKGYTPQKEPLAGLTTMFRQLTNYKKDISGIVIAAMLITFISIVGSY
                     YLQLIIDRFIPSKNINGLAILAGSLLVVYVFNSLFNYLRDVLLTRLDQKLTSQISLRYI
                     HHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSSTIISMFLDVGVMVIIGIVLSLYDR
                     SLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNAQLSSAIIEDLKGVETLKVLRLEN
                     IRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQYGLVTIILFQGAILVIQDRLSIGT
                     VMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLNEVLQIDTEKSDTNSQDQADLVGP
                     INIQHVDYSYEYSRPILQDINLQIGCNDKLAIVGLSGSGKSTLAKLLVGFYLPTQGQIE
                     FNQHKTTEINLCDIRQYVHYLPQSPQLFSGTIKDNLLMRLDREVSIEEIDNACKLALIY
                     NDIQEMPLKYETKLDEEATVLSGGQKQRLTLARALLTSARVLIFDESTSSLDPITEKRI
                     VENLLEIEDRTMIFIAHRLSIAKKVNKVVVMRDRKIIEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7427..7588)
                     /locus_tag="ctg10_54"
                     /transl_table=11
                     /translation="MTYRKLNFNELSEVSGGWGVTPWSVAWQTGKVAYSLVKHRRSYYA
                     GYQDSPFH"
     CDS             complement(7630..7788)
                     /locus_tag="ctg10_55"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVGDIINSIKKWTQSCYEG
                     YQDSPFH"
     CDS             complement(7790..7957)
                     /locus_tag="ctg10_56"
                     /transl_table=11
                     /translation="MMKILTTAELEGINGGFKHNIWYYYGWGRASCIGTQRRNPSAFLN
                     HPNFIVLGGN"
     CDS             complement(8185..8952)
                     /locus_tag="ctg10_57"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEAYLAILDIELDNQLSGIDVAEQIRKRAEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGKQIESIADRLRIDIDEAYARYQNYMNSNQKHQEKFTYEPTHGVKRQVDF
                     ENLYYIESVKNTNRRLRIVGKDIRIEYRGELGQINNKRLLKVNQSTLINPKAIQEFNRK
                     ERVVYFDENQEIKITVSYRKIKSLINFLEKENH"
     CDS             complement(8960..10273)
                     /locus_tag="ctg10_58"
                     /transl_table=11
                     /translation="MIHLTVGQGLTSSILNIIEIIFIYQLVTSDFSLGLVIIDFLAVLM
                     IIFFSIVFFMLGSLYPVLIVFYFWLVDRIKSNSYIVINSILAMCISIVMASLFDLVDHY
                     TYTFFLQGKTDIALLGWLIPINDLIITIVVAILAIKVVRPKLRWIRINFPRPIGLWQIT
                     AILFMLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCATGFINFVKSSQQTQRQQQII
                     DKYQAQIANANQLNQQYNEIRRERHDTRNMLLSIQGYIRDHKDKEAEELLATFLQNDTV
                     EKHYGEIDNALDKIKISGLHNLIKEKAYKIVEKGIPFSFEVNAEIDELPGSEIKTARII
                     GILMDNAIEATFKQAKPYIQFALLKHSAKVYELVIANSIEQKLNINTALKFEHSTKEGH
                     QGIGLSNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             complement(10270..10401)
                     /locus_tag="ctg10_59"
                     /transl_table=11
                     /translation="MLKKSYKFLSRKELSKVLGGWGYSLAFKSPRSWERAVLNWIKR"
     CDS             complement(10428..10592)
                     /locus_tag="ctg10_60"
                     /transl_table=11
                     /translation="MVDLNLETKKNLVIINLFYIGLIALYCILHAGPLNFLVFLGMLVL
                     ANIAEFVVK"
ORIGIN
        1 tgcttcttca agtcagcaat cttttccttg gcatcttggg cagccttgta atcttctttc
       61 ttagcagccg ctttttgctt cttttcttct gcttcgatat ctttttcaat tgccttagca
      121 tcacgtgctg ggtgctttgc tgctaagtga gcagcagtca tatcgattaa gtcgatagcc
      181 ttgtcaggta atgcacgttg tggcatgtat tgaacagagt aatcaacagc agcttggaga
      241 acgtcatctg gtaactttac attgtggtga cgttcgtaca agtcacggat acctttaaga
      301 atagctacag tatcagcctt gcttggagca ttaacagtaa cagcattgaa ccgccgtgct
      361 aatgcagcat ccttcataat agtgttccgg tattcatctt gagtagttgc accgataact
      421 gttagttcac cacgagataa tgctggctta ataatgtcag acataccctt agaaccacta
      481 gaatcaccag ttgaaccggc accgataatt tggtgaattt catcgaagaa gaggatgatg
      541 tttccagcct tcttgacttc atcaaccaac ttttgcatgt tttcttcaaa gctaccacgg
      601 tattgagtac ctgcttcaag gccagaaata tcgatactga taatttcctt gtccttgata
      661 gcagctggta catcgccgga aacaattgct tgtgctaatc cttcaacaac agcagtctta
      721 ccaacaccag cgtccccaac taatacaggg ttgttctttg tccgccggct taaaatttca
      781 gctgtttctt ggatttcctt gttccgacca ataacagggt caagttcatg ttcacgagct
      841 tcttgagtta agtttcgacc taacttgtgt aagatactgt ccttacctgc gttaggttga
      901 gggccaggtt gcccaccttg ttgaggattt gcaccgcctg gcaattgacc agttctacga
      961 tattcagcaa attcttctgg tgttacttca cgaccattga ttaggtaacg ccgattatca
     1021 gaattgaaac cattcatgcc acccattaat tgattaaaga tgtcattcat gtcgttgtca
     1081 aatggattca ttgggttttg agccatatgc aatccctcct caattaaata taatattttg
     1141 ttttctaagt ttcgtagtct aagtattcta gaagtcaaaa gttaacgcat ttaacttcct
     1201 gtggctacag caaagccaca atctcattcg aggtaatgct cttctagttc tttaaggacc
     1261 ttccacatgc tcttgtcctg agcacgagcc aaggcatcaa gatcacgcag gttaagcgag
     1321 gtcgaactag actgtggttt gttaaacgat ttgtgtaaag tcgtgtagcc gtaaccggaa
     1381 cgcttggaaa cttgataaat ggtcaagtgg ttaacttcca aataatgttt gatgtcgatc
     1441 cgcattgcta cccacttcct ttacaattaa tattatatca catttgtgga gtaagacaac
     1501 aaaaaagacg cgaaaaaaat aaaaaaattg tagaatataa atctaatatt aaattaaagg
     1561 cgaaataata atcacaaaca ttttcacact ttattatatt tacatttgtc atcaataaat
     1621 aattttgtaa ttaataattt ttctcaatca actcttgaca aaaattaaaa aataattaga
     1681 ataattaata atcagttaat caaaaggagg acacaatgat gagcactgcg acaattcact
     1741 tgaatcaagc gtatgtcttc tggtttagcg tgattaccgt ccgctaacca gcagtgattt
     1801 tatcattgtg atgttcccgg atgaccccca aacatccgag agcctctttt atactcattc
     1861 caatctgatc aagaagccct ggatgttttt cctatagcat tcagggcttc ttttatttct
     1921 aaatctacat attatatagg agggatttat catgccaact actaaaaaag aaattctcaa
     1981 tcgtcttaac aataatttcg ctaaactcac tcctggcggg atccgcgaat ttgactacca
     2041 agtcagcgca atccctggca tcattaaact aacattaggt gaaccagact ttaatgtgcc
     2101 agccgcaatg aagcaggccg caatcgatag catcaatgcc aatgattcac actatgctcc
     2161 gggaaatggg accttagcac tacgccaagc aatcgctcac ttcatgcaag atcgttacga
     2221 gctggaatac gatccagaaa acgaaattgc tgttacagtt ggcgcaacag agggaatttt
     2281 cgcttctctt tctactatta ttaatcctgg cgacgaaatt atcattccaa ccccaacttt
     2341 ccccttctat atagctgtca caaagattct tggtgggatt ccgattgaag ttgatacaag
     2401 cagcgatgat tttgttctca cacccgcaag actccaaagc gtactagaag aacatcctaa
     2461 tgccaaggga ctagttctta actatccctc caacccaact ggtgttactt acacccaaga
     2521 tcaaattaaa gcactagcca atacggttaa atcaactaac ctgattgtaa ttgccgatga
     2581 aatttactcg gaactggttt acggagctac tcatacttca atcgctaatt acatccccga
     2641 acaaacgcta attttaaatg gtgcctcaaa gtcacatgca atgactggtt accgaattgg
     2701 ttttatcgct gggccgcaag aattgatgaa atcagtgagt gccattcacg cgatgttagt
     2761 aaccgctgct tctaatccag caatggccgc tgcagtagcc gcatttggta ctgacgaagg
     2821 aaaaacagct actcaagaaa tgaaagatgc ttatgagcaa cgacgagact ttgttgttaa
     2881 taacctccaa aaattagggt tcgagctgat taatcctcaa ggagccttct acgtttttgt
     2941 taagattcct gaacaatatg gtaatgatga tcttaaattt gcgacagatc ttgctaatga
     3001 aggaaaagtt gctgtgattc ctggttcctt ctttggagct ggcggccaag gatatgttcg
     3061 aattagttac gccaccagta tggaaaatct aaccggagct cttgataaca ttgcggcctt
     3121 cattaataag gaggattaac atgacgaaaa tcttgatgac tagcgtgcgg gatgatgaac
     3181 aaaccgccat taatgaatac gcaaaagaac ataatatcga aatcatcaca acgccgaaat
     3241 tgattgacga tgctgttgaa ttaacggcca atgttgatgg actcgtgatt cagcaacgta
     3301 gtaaagttcc ggctgatatt tatgaaaagc tacataccaa taggctcaag cagattacaa
     3361 cgcggaccgc gggatttgac atggtcgaca tcaaaaaggc taacgaaaat ggcttagtcg
     3421 tcaccaatgt accagcatat tcaccgcgga gtgtcgccga gtttgcatta atgcagattt
     3481 tccgattgct tcggaaaact taccgctttg accaccaagt cgccgaaaat gacttccgct
     3541 ggtttagcga tgaacagtca atcgaaattc acacggcaag gattggaatt attggggtcg
     3601 ggcgtatcgg cggaacactt gctaaacttc tcaatgccct cggtgccact gttcttggtt
     3661 atgacacgaa tccgcgcact gacctcgatg gaattgtcca gttcgtttct aaagaagaat
     3721 tactaaagca agccgatgtt gttagtctcc acgttgatct aaatccaact tctaaaggtt
     3781 tgctgaccgc taacgacttt gcaatgatga aaccaactgc tggtttggtc aatgctagtc
     3841 gtggtccagt cgttaataca gctgacctcg tcacagcatt aaaagctggt gaaatcgccg
     3901 cggccgccct cgataccttt gaaggtgaag aagcagttgc agctgcggat cgccgagaaa
     3961 aagggcttga tgatcagccc cttgttaaag aattacacga aatggataat gtcattctta
     4021 cgcctcacat tgccttcttt actaatttag cggtcaaaaa tatggtggat atttcacttg
     4081 atgatgtgat gacaatcctt aatggcagaa aatcaccaca tgaaattact ttataattga
     4141 gcaccctcat tgaccaaaag tatcgtctcg attacactat gggtattaaa ggagggaacg
     4201 gttatgagta aatataaagt aacagcaact aagacaacaa cggggatgca ggtttcagca
     4261 ggtacccgtg gttttgaaat tacctttgat gaaccagaaa gtactaatac ggggatgaat
     4321 ccagtagaaa ttcttcttgc gtcatttggt gcctgtcagg caatcactgc ccaagcatta
     4381 gctaaaaagc gtaactttga cttacgagct ttttgggtaa caatcgaggg tgatcttggt
     4441 cgtgaagacg ttgctgatgg caagaatgtt cgtaagttta ctgagatccg ttaccaacca
     4501 cacctacgca gcaacgagtc tgatgaagac attaagaagt ttctcgctga cgttgcagca
     4561 aagtgtcccg tggaaaatac tctgacctac ggaacgaaat ttgttcaaga tggatttgta
     4621 aaagttgatt agttgaaaaa acgccttgga attttctagg gcgttttttt aatagttaac
     4681 ctatacgaat tctgcaagaa acttaacgaa ttttgcaaaa tgtcctttaa attagatctt
     4741 tcattataat aaggtacaca tactgtctta gggggagaac taatgaaaat tcatttcaat
     4801 aaggactttt ggcgggatgg tttcttttat atatacttat tacttttgtt tctctggatt
     4861 gctccatttt cagatggttc gcttccatta gatgaggagc tattatgtat cttctttata
     4921 atttttacta tcggttccat gctcgcaatt atgtttaata aagactgaaa aaaggctcca
     4981 acagcaatgt tcggagcctt ttatgcattc cacaaattat agtattcttg atgatgattc
     5041 aaaagttcct ggtgagtacc ctgttcaatg atttttctgt cgcgcattac taccacttta
     5101 ttgactttct tagcaatcga aagacggtgg gcaataaaaa tcattgtgcg gtcttcaatt
     5161 tcaagcaaat tctcaacgat tcttttttca gtaattggat ctaagctact tgttgattca
     5221 tcaaaaatta aaacacgcgc agaagttagg agtgctcgtg caagcgtcaa gcgttgtttt
     5281 tgaccaccag ataatacggt tgcttcttca tctagttttg tttcatattt taagggcatc
     5341 tcttgaatat cgttatagat taatgccaat ttacatgcat tatcgatttc ttcaatagat
     5401 acttcacggt ctaatctcat tagcaagtta tctttgattg ttcccgaaaa taattgtggc
     5461 gattggggta agtaatgtac atattgtcta atatcgcaaa gattaatctc tgttgtttta
     5521 tgctgattaa attctatctg cccttgagta ggtaaataaa agccaactaa caactttgcc
     5581 aaggtcgatt taccagaacc gctcaaccct acaattgcca atttgtcatt acaaccaatt
     5641 tgaagattga tatcttgtaa aattggacga ctatattcat atgaatagtc aacatgttga
     5701 atgtttatcg gccctaccaa atctgcttga tcctgagaat tcgtatctga cttttcggtg
     5761 tcaatttgca gcacctcatt caatcgatta ttcgctactt tagcttcttg gagtttaggt
     5821 tgaagattaa taatattttg caatggactg acaaaaaagg ctaataacgc attaaaagcc
     5881 atcacggtcc caatacttaa tcggtcctga attaccaaaa ttgccccttg aaaaagaatg
     5941 attgttacta agccgtattg aatccacatt ttaattgcat cctgaaaaga tttagtttta
     6001 acatatgtta gattctttcg taagaaatcc gcaaattgtt tttcaacatt tttataacgg
     6061 atattttcaa gtcgcagtac tttcaacgtc tctacgcctt ttaaatcctc aataatagca
     6121 gagcttaatt gagcattact ttccatctgt tcctgatcaa gtttagcaaa gcgcttatta
     6181 aaggcataaa tgataatgac ataaattgga atggtactaa ttgtagttaa aaataatgac
     6241 cgatcatata aagaaagaac aattcctata atcaccatca cgccaacgtc taagaacatt
     6301 gaaataatag tgcttgataa ggcatcaata atcttattaa tgtcattaaa ccgtgaagta
     6361 atttctcctg tttttcttgt ggagaaaaat cgcatcggta gacgataaac atggtgaata
     6421 tatcgcagac ttatttgtga tgtcagtttt tgatccagcc tagtcaaaag aacatctcgc
     6481 agataattaa aaagagaatt aaacacataa actactaata aactaccagc aaggatcgct
     6541 aagccattaa tatttttcga gggaataaac cgatcaataa ttaattggag atagtatgaa
     6601 ccgacgatgc tgatgaaagt aattaacatt gccgcaatga caattcctga tatatctttt
     6661 ttataattag ttaattgtcg aaacatcgtc gttaatccag ctaaaggctc tttttgtggc
     6721 gtatatccct tagcaggcga aaaaagtaaa catacacctg accataaacg atcaaattca
     6781 tctcgagtta ttttttgtac ttttgtagca gggtctggat cagctacata gatgtaatct
     6841 tgatcagcct taaaaacgac acagtaatga agtaaatcat ccttaatcac atgtgcgatc
     6901 aacgggtaag taatttcagg atcatcaaac aatgatatat ctgcttgaat gggtataacg
     6961 tctaatccaa gatgttttgc tgcttttaca agtcctaagg cagttgttcc ttgcttagtt
     7021 gtccgtgcta agtcccgtaa ttttgcgatt gggtaaacag aaccgaaatt atgcaaaatc
     7081 attgctaaag cagcgactcc acaatctgct tcatcaactt gagctacata atgaggataa
     7141 ttgattttcc ttcaccttac tttctaatta gacaaagaaa taaagtccaa aattaataat
     7201 gattctgggc tttatattct tataagatac tatttatttt taaataaaat tcgtagagcc
     7261 gcaaaaatac caatgattgt gcaagctata catataattg tttcataaat gttacttgcc
     7321 ttgggaattg ctaagaccca gaagaatgta actataatat agatataaaa atcaagattg
     7381 gtgtaaaaat cgtggttaaa tttcataatc attaagttat aaactattag tgaaatggac
     7441 tatcctgata gccagcataa tacgaacgcc gatgtttaac aagcgaataa gcaacttttc
     7501 ctgtttgcca cgcaacactc caaggagtaa ctccccatcc accagaaact tcgcttaatt
     7561 cattaaagtt caatttacgg taagtcattt taattacctc catctcaaaa taactatcct
     7621 ttattattcc taatgaaacg gactatcttg gtaaccttca taacaagatt gagtccattt
     7681 ctttatagaa ttaataatgt ctccaactag ttcattaacc tgcgaagata agctccatcc
     7741 accagaaact ttgcttaatt catcaaagtt caatttacgg taagtcattt taattacctc
     7801 ctaatacgat gaagttagga tgatttaaga atgcactagg gttgcgacgt tgtgttccaa
     7861 tgcatgatgc tcttccccaa ccatagtagt accaaatgtt atgcttaaat ccaccattga
     7921 ttccctcaag ttcagcagta gtaagaattt tcatcataat tactcctcct cgtaattatt
     7981 aattttaata aatcaagttt ttccctacct tgattacact attagtatat aggcaaaaaa
     8041 gcattttggg agtattttgt aaaattcgta aacctttctg cataattcgt agtaaaaatc
     8101 ttgaaaacgt ttactaaaat tacttgataa taaaaaagaa actatgacag cttttttgtc
     8161 acagtttctt tgaaaataaa atagttagtg gttttccttt tcaagaaaat tgattaatga
     8221 ttttattttt cggtaactaa cagttatctt aatttcctga ttttcatcaa agtaaaccac
     8281 acgttcttta cgattaaatt cttggattgc tttgggatta atcagcgtac tttgattcac
     8341 tttcaataaa cgcttgttat taatttgacc taactcgcca cgatattcaa tccgaatatc
     8401 ttttcccaca atccgtaacc gtcgatttgt gttttttact gattcaatat aatagagatt
     8461 ttcaaaatca acttgccttt ttactccatg agtcggttca taagtaaact tttcttgatg
     8521 tttttgatta ctgttcatgt aattctgata gcgagcatat gcctcatcaa tatcaatccg
     8581 gagtcgatcc gcaatcgatt caatctgttt cccttttgat atatagtcga atggctcaat
     8641 tcggcgcgaa acagtataag gtaaatattc ttgataagca gttacaaaga taatttcggc
     8701 aaattcagct cttttgcgga tttgctccgc aacatcaatc ccactaagtt gattgtctag
     8761 ctcaatgtct aaaatcgcca aataagcctc atctttgata ctatcaatca cttcttgcgg
     8821 atcatttgtc cgcaaatata attctatgtc ataactattt ggagtagcgt taatcaattt
     8881 tcgctgagaa actagacgct cagtataatc agcttgataa tcatcatttt ccaaaataat
     8941 tacttttaac attttattct cactttccct gaataaaaca agtcatcata attaccttat
     9001 ctttaacttc cgctgaaaaa gaataatggt catcattttc taccaactgt gtcacatttg
     9061 aaaggccaat tccttgatgc ccttccttag tcgaatgttc aaattttagt gcagtattaa
     9121 tattaagttt ttgctcaatt gaattagcaa ttaccaattc ataaactttt gcactatgct
     9181 taagcaatgc aaactgaata tatggtttag cttgtttaaa ggttgcttca attgcattgt
     9241 ccattaaaat tccgataatt ctagcagttt ttatttctga acccggcaac tcgtcgatct
     9301 cagcattaac ttcaaatgaa aatggaatac ctttttctac tattttataa gccttttcct
     9361 taataagatt atgcaaccct gaaattttaa tcttatctaa tgcattatca atttcaccat
     9421 aatgcttttc aactgtatca ttttgaagaa acgtcgctaa taattcctct gcttccttat
     9481 ctttgtgatc acgaatatat ccttgaatac tgagaagcat attgcgtgta tcgtgacgtt
     9541 cacgccgaat ctcattgtat tgttggttca attgattggc gttggcaatc tgtgcttggt
     9601 atttatcaat gatttgttgc tgtcgttgcg tttgctgact gcttttaacg aaattaataa
     9661 atccggttgc acatactacg ataattatca aatacattat taacaacagc gaggcatact
     9721 tatttgctac cccgtccttt tcggcaatag cagttaacca cacataaagc atgaacaaaa
     9781 ttgctgtaat ttgccataac cctatcggtc gaggaaaatt aatcctaatc catctcagtt
     9841 tgggacgaac tactttaatt gctaagattg caactacaat agttatgatt aaatcattaa
     9901 ttggaataag ccatcctaaa agtgctatat ctgtctttcc ttgtaaaaaa aacgtataag
     9961 tatagtgatc tactaaatcg aataaagatg ccattacaat actaatacac atcgcaagaa
    10021 tactatttat aactatataa gaattagatt ttattctgtc aactaaccaa aaataaaata
    10081 ctataagtac tgggtatagc gatcctaaca taaaaaatac tattgagaaa aatataatca
    10141 tcaagacagc taaaaaatca attattacta atcctaatga aaagtcgcta gttaccaatt
    10201 gatatataaa tattatttca ataatattta atatagatga cgttaatcct tgtcctacag
    10261 ttaaatgaat catcttttaa tccaatttaa aactgctctt tcccatgaac gaggactttt
    10321 aaaggcaagt gaataccccc aaccacctaa tactttagat aattctttcc ttgataaaaa
    10381 tttatatgat ttttttaaca taattacctc caataaataa caattaccta tttaactaca
    10441 aattcagcaa tattagccaa aactaacatt cccaaaaaca ctaaaaaatt cagtggccct
    10501 gcatgcaaaa tacaatacaa ggcaatcaat ccgatataaa aaaggttaat gattaccaaa
    10561 tttttcttcg tttctaaatt caaatccacc atataactaa ctcctacttt atccatccct
    10621 ctgataatgc aaaagaaata ataattgtta aaacaaagca agcaattgca atcataattg
    10681 cgcgttcagc actcgggcgc acaacttctc ctcctttagt agataaccac aggctcattt
    10741 ttatgtaagt cactaaaagc ttgaccagct acgtctggat gcatgttaat acaaccatgc
    10801 gatccaccgc ctttagcaag ataagcctgt ttcgaccaat cgtgacgcca acttgcatca
    10861 tgaaatccac atccactatc agtaaatggt gaccaatatt gaactttgct agcgtatttc
    10921 gaaccatcat cgttaagtcc ccgaagaaca gacggtgttt gctggtacat gatataccag
    10981 acacccttcg gcgtctcgtt atctttgtta ttggtcccac taacaatgtc agtgctaaga
    11041 acacatttac cattcttata gaaccacgca tgttggtcgg ctagtgaaac ttcggcgtaa
    11101 gtgttcccta taccattgtt gcttgtagta ttatacccag ttccttgttg attataacct
    11161 ttaccataga tatcattttt ggcgtttact gtttgcttat ttgcaaccaa tgcattcgta
    11221 agagtctttc cagcttgttt tttactgatc ttccaaccat atgagccagc atcggttgtt
    11281 ttgatcactg atccatcatg tgttttgaat tcaaatgatt tgccaagagt tgcttgggta
    11341 ttattaattt catcaatctt tgaactagct gctccagtgt caaagtgata ttttccattt
    11401 tgatatgttg ctctggtaat aatctcacca caatttaatt gatacttttt gttttgtact
    11461 tggtatgtta cagttcgttt tgataattct tcgagcttta ctttttcatt ttgaacagtt
    11521 ttactatttg cagaaagcgg agccttgtat actggcctca agtaaatagt tccgccagca
    11581 atctcattct caactttatt atgcaaacca tctaaactgt attgagtacc accaactgct
    11641 ggttttactt gtactcggcc attttcgtat acagcgtaag cattaacagg agcttttcga
    11701 ccattattta attctgttac cttttgactg actgcttgat caatctttga tacttcatct
    11761 tgattaacat tttgaggctt aatcgcaatg ttctttgcct tagatgatgg gaagaaagta
    11821 tactgactac gtaatgcatt tttaattttt tgttcgtcag cactactaaa ctttgctact
    11881 gattgtttat ccgtaaatac taactcattg ttaacataaa tttttggcga ttgtggatta
    11941 tcttgtaact tctttaatgc ttgcttagca gtcaatccac caaccgacac attatcaatc
    12001 ttaacgttct tattaaaatg acgacgctgg tgaatagtca tgcagccaac caccagcact
    12061 aataagcaca aagtgattat ta
//
