LOCUS       c00038_JAJGTN0..       12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGTN010000027.1 Limosilactobacillus reuteri strain R.n.1-B
            scaffold27, whole genome shotgun sequence.
ACCESSION   JAJGTN010000027
VERSION     JAJGTN010000027
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 10:58:37
            Original ID  :: JAJGTN010000027.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 70114
            Orig. end    :: 82265
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[75114:77265](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7151)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1875..3062
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     1.7e-72. Score: 236.3. Matches aSDomain:
                     nrpspksdomains_ctg38_46_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 269.9; E-value: 6e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_46"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.3e-07,
                     bitscore: 22.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFAKLTPGGIREFDYQVSAIPGIIKLTLGEP
                     DFNVPTAMKQAAIDSINANDSHYAPGNGTLALRQAIAHFMQDRYQLDYNPENEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSSDDFILTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTVKSTNLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGFELINPQGAFYVFAKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIASFINKEN"
     aSDomain        1983..3035
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_46_Aminotran_1_2.1"
                     /evalue="1.70E-72"
                     /label="ctg38_46_Aminotran_1_2.1"
                     /locus_tag="ctg38_46"
                     /protein_end="387"
                     /protein_start="36"
                     /score="236.3"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPTAMKQAAIDSINANDSHYAPGNGTLALRQAI
                     AHFMQDRYQLDYNPENEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSSDDFILTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTV
                     KSTNLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGF
                     ELINPQGAFYVFAKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             3064..4059
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 298.7; E-value: 5.8e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_47"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTADV
                     DGLVIQQRSKVPADIYEKLHTNGLKQIATRTAGFDMVDIKKANENDLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSTEIHTATIGIIGVGRIGGTLAKL
                     LHALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPTSKGLLTANDFEM
                     MKPTAGLVNASRGPVVNTADLVTALKKGTIAAAALDTFEGEETVAATNRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMAILNGEKSPHEITL"
     CDS             4128..4556
                     /locus_tag="ctg38_48"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             complement(5001..7151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 321.7; E-value:
                     1.6e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_49"
                     /sec_met_domain="TIGR01193 (E-value: 2e-275, bitscore:
                     907.7, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.2e-39, bitscore:
                     127.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYLHYVAQVDEADCGVASLAMILRNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFDRLWSGVCLLFSPAKGYTPQKEPLAGLTTMFQQLTNY
                     KKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLTILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAILVIQDRLSIGTLMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDTEKSDTNSQDQTDLIGPINIQHVDYSYEYSHPILQDINLQIGCNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQLPQLFSGTIKDNL
                     LMGLDREVSAEEIDNACKLALIYNDIQEMPLNYETKLDEEATALSGGQKQRLTIARALL
                     TSARVLIFDESTSSLDPITEKRIVENLLEIEDCTMIFIAHRLSIAKKVNKVVVMRDGKI
                     IEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7428..7586)
                     /locus_tag="ctg38_50"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVRDIVNSLNKWAQSCYAG
                     YHDSPFH"
     CDS             complement(7781..8554)
                     /locus_tag="ctg38_51"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEVYLAILDIELENQLSGIDVAEQIRKKAEFAEIIFITAYQEYLPYTVSHR
                     IEPFDYISKGEQIESIADRLRTDIDEAYARYQNYMNSNQKHQEKFTYEPTHGVKRQVDF
                     ENLYYIESVKNTNRRLRIVGKDIRIEYRGELGQVNNKHLLKVNQSTLINPKAIREFNRK
                     ERVVYFDENQEIKITVSYRKIKSLVNFLEKDNNGL"
     CDS             complement(8562..9374)
                     /locus_tag="ctg38_52"
                     /transl_table=11
                     /translation="MLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCATGFINFVKSS
                     QQTQRQQQIIDKYQAQIASANQLNQQYNEIRRERHDTRNMLLSVQGYIRDHKDKEAEKL
                     LATFLQNDTLEKHYDEIDNALDKIKISGLHNLIKEKAYKIVEKGIPFSFEVNAEIDELP
                     GSEIKTARIIGILMDNAIEATFKQAKPYIQFALLKHSPEVYELVIANSIEQKLNINTAL
                     KFEHSTKEGHQGIGLSNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             complement(9871..10002)
                     /locus_tag="ctg38_53"
                     /transl_table=11
                     /translation="MLKKSYKFLSRKELSKVLGGWGYSLAFKSPRSWERAVLNWIKR"
     CDS             complement(10029..10193)
                     /locus_tag="ctg38_54"
                     /transl_table=11
                     /translation="MVDLDLETKKNLVIINLFYIGLIALYCILHAGPLNFLVFLGMLVL
                     ANIAEFVVK"
     CDS             complement(10317..11642)
                     /locus_tag="ctg38_55"
                     /transl_table=11
                     /translation="MTIHQRRHFNKNVKIDNVSVGGLTAKQALKKLQDNPQSPKIYVNN
                     ELVFTDKQSVAKFSSADEQKIKNALHSQYTFFPSSKAKNIAIKPQNVNQDEVSKIDQAV
                     SQKVTELNNGRKAPVDAYAVYENGRVQVKPAVGGTQYSLDGLHNKVENEIAGGTIHLKP
                     EYTTPLSANSKTVQNEKAKLEELSKRSVTYQVQNKKYQLNCGEIITRATYQNGKYHFDT
                     GAANSKIDEINNTQATLGKSFEFKTHDGSVIKTTDAGSYGWKISKKQAGKTLTNALIEN
                     KQTVNAKNDIYGKGYNQQGTGYNTTSNNGIGDTYAEVSLADQHAWFYKNGKCVLSTDIV
                     SGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKYASKVQYWSPFTDSGCGFHDASWR
                     HDWSKQAYLAKGGGSHGCINMHPDVAGQAFSDLHKNEPVVIY"
ORIGIN
        1 tgcttctttt cttctgcttc gatatctttt tcaattgcct tagcatcacg tgctgggtgc
       61 tttgctgcta agtgagcagc agtcatatcg attaagtcga tagccttgtc aggtaatgca
      121 cgttgtggca tgtattgaac agagtaatca acagcagctt ggagaacgtc atctggtaac
      181 tttacattgt ggtgacgttc gtacaagtca cggatacctt taagaatagc tacagtatca
      241 gccttgcttg gagcattaac agtaacagca ttgaaccgcc gtgctaatgc agcatccttc
      301 ataatagtgt tccggtattc atcttgagta gttgcaccga taactgttag ttcaccacga
      361 gataatgctg gcttaataat gtcagacata cccttagaac cactagaatc accagttgaa
      421 ccggcaccga taatttggtg aatttcatcg aagaagagga tgatgtttcc agccttcttg
      481 acttcatcaa ccaacttttg catgttttct tcaaagctac cacggtattg agtacctgct
      541 tcaaggccag aaatatcgat actgataatt tccttgtcct tgatagcagc tggtacatcg
      601 ccggaaacaa ttgcttgtgc taatccttca acaacagcag tcttaccaac accagcgtcc
      661 ccaactaata cagggttgtt ctttgtccgc cggcttaaaa tttcagctgt ttcttggatt
      721 tccttgttcc gaccaataac agggtcaagt tcatgttcac gagcttcttg agttaagttt
      781 cgacctaact tgtgtaagat actgtcctta cctgcgttag gttgagggcc aggttgccca
      841 ccttgttgag gatttgcacc gcctggcaat tgaccagttc tacgatattc agcaaattct
      901 tctggtgtta cttcacgacc attgattagg taacgccgat tatcagaatt gaaaccattc
      961 atgccaccca ttaattgatt aaagatgtca ttcatgtcgt tgtcaaatgg attcattggg
     1021 ttttgagcca tatgcaatcc ctcctcaatt aaatataata ttttgttttc taagtttcgt
     1081 agtctaagta ttctagaagt taaaagttaa cgcatttaac ttcctgtggc tacagcaaag
     1141 ccacaatctc attcgaggta atgctcttct agttctttaa ggacctccca catgctcttg
     1201 ccctgagcat gtgccaaggc atcaagatca cgcaggttaa gcgaggtcga actagactgt
     1261 ggtttgttaa acgatttgtg taaagtcgtg tagccgtaac cggaacgctt ggaaacttga
     1321 taaatggtca agtggttaac ttccaaataa tgtttgatgt cgatccgcat tgctacccac
     1381 ttcctttacg attaatatta tatcacattt gtggagtaag acaacaaaaa agacacgaaa
     1441 aaaataaaaa aattgtagaa tataaattta atattaaatt aaaggcgaac taataatcac
     1501 aaacattttc acactttatt atatttacat ttgtcatcaa taaataattt tgtaattaat
     1561 agtttttctc aatcaactct tgacaaaaat taaaaaataa ttagaattat taataatcag
     1621 ttaatcaaaa ggaggacaca atgatgagca ctgcgacaat tcacttgaat caagcgtatg
     1681 tcttctggtt tagcgcgatt accgtccgct aaccagcagt gattttatca ttgtgatgtt
     1741 cccggatgac ccccaaacat ccgagagcct cttttatact cattccaatc tgatcaagaa
     1801 gccctggatg tttttcctat agcattcagg gcttcttttt tctaaatcta catattatat
     1861 aggaggaatt tatcatgcca actactaaaa aagaaattct caatcgtctt aacaataatt
     1921 tcgctaaact cactcctggc gggatccgcg aatttgacta ccaagtcagc gcaatccctg
     1981 gcatcattaa actaacatta ggtgaaccag actttaatgt gccaaccgca atgaagcagg
     2041 ccgcaatcga tagcatcaat gccaatgatt cacactatgc tccgggaaat gggaccttag
     2101 cactacgcca agccatcgct catttcatgc aagatcgtta ccagctggac tacaatccgg
     2161 aaaacgaaat tgctgttaca gttggcgcaa cagaaggaat tttcgcttct ctttctacta
     2221 ttattaatcc tggcgacgaa attatcattc caaccccaac tttccccttc tacatggctg
     2281 tcacaaagat tcttggtggg attccgattg aagttgatac aagcagcgat gattttattc
     2341 tcacacccgc aagactccaa agcgtcctag aagaacatcc taatgcaaaa ggactagttc
     2401 ttaactaccc ttccaaccca actggtgtta cttacaccca agatcaaatt aaagcactag
     2461 ccgatacggt taaatcaact aacctgattg taattgcaga tgaaatttac tctgaacttg
     2521 tttacggagc tactcatact tcaatcgcta attacatccc cgaacaaacg ctaattttaa
     2581 atggtgcctc aaaatcacat gcaatgactg gttaccgcat tggttttatc gctgggccgc
     2641 aagaattgat gaaatcagtc agtgctattc acgcaatgtt agtaactgct gcttctaatc
     2701 cagcaatggc cgctgcagta gctgcatttg gtactgacga aggaaaaaca gctactcaag
     2761 aaatgaaaga tgcctatgag caacgacgag actttgttgt taataacctc caaaaattag
     2821 ggttcgagct gattaatcct caaggagcct tctacgtttt tgccaagatt cctgaacaat
     2881 atggtaatga tgaccttaaa tttgcgacgg atcttgctaa tgaaggaaaa gttgctgtga
     2941 ttcctggttc cttctttgga gctgggggcc aaggatatgt tcgaattagt tacgccacca
     3001 gtatggaaaa tttaaccgga gctcttgata acattgcatc cttcattaat aaggagaatt
     3061 aacatgacaa aaatcttgat gactagtgtg cgggacgatg aacaaaccgc cattaacgaa
     3121 tacgcaaaag aacacaatat cgaaatcatc acaacgccga aattgattga cgatgctgtt
     3181 gaattaactg ccgatgttga tggactcgta attcagcaac gcagtaaagt tccagccgat
     3241 atttatgaaa agctccatac caatgggctc aaacaaattg cgacacggac agctggattt
     3301 gacatggtcg acatcaaaaa ggctaacgaa aatgacttag tcgtgaccaa tgtaccagca
     3361 tattcgccgc ggagtgtcgc cgagtttgca ttaatgcaga ttttccggtt gcttcggaaa
     3421 acttaccgct ttgaccacca agtcgccgaa aatgacttcc gctggtttag cgacgaacaa
     3481 tcaacggaaa ttcatactgc cacaattggg attattggtg ttggacgcat tggcggaacc
     3541 ctggcaaaac ttcttcatgc attaggtgct accgttctag gatatgatac gaatccgcgc
     3601 actgacctcg atggaattgt ccagttcgtt tctaaagaag aattactaaa acaagccgat
     3661 gttgttagtc tccacgtcga tttaaatcca acttctaaag gtttattgac tgctaacgac
     3721 tttgaaatga tgaaaccaac tgccggcttg gtcaatgcta gccgtggtcc agtcgttaat
     3781 acagctgatt tagttacagc ccttaaaaaa ggaacaattg cagcagcagc tcttgacact
     3841 tttgaaggtg aagaaacggt ggcggccaca aatcgccgag aaaaaggact tgacgatcag
     3901 ccgcttgtta aagaattaca cgaaatggat aatgtcattc ttactcccca cattgccttc
     3961 tttactaatt tagcagtcaa aaacatggtg gatatttcac ttgatgatgt gatggcaatc
     4021 cttaatggcg aaaaatcacc acatgaaatt accttataat tgagcaccct cattgaccaa
     4081 aagtatcgtc tcgattacac tatgggtatt aaaaggaggg aacggctatg agtaaatata
     4141 aagtaacagc aactaaaaca acaacgggga tgcaagtttc agccggtacc cgtggttttg
     4201 aaattacatt tgatgaacca gaaagtacaa atacggggat gaatccagta gaaattctcc
     4261 ttgcatcatt tggtgcctgt caggcaatca ctgcccaagc attagctaaa aagcgtaact
     4321 ttgatttacg agctttttgg gtaacaatcg agggtgatct tggtcgtgaa gacgttgctg
     4381 atggcaagaa tgttcgtaag tttactgaga tccgttacca accacatctt cgcagcagcg
     4441 agtctgatga agacatcaag aagtttctcg ctgacgttgc cgcaaagtgt cccgtggaaa
     4501 acactctgac ctacggaacg aaatttgttc aagatggatt tgtaaaagtt gattagttga
     4561 aaagggagcg agacagaagt cactcgtgac ttcgttttcg agcccccgca agcaacaata
     4621 ggcctccaac attcggtttt accgagcgtt ggaggccatt ggtgtactgc gccatttgtt
     4681 tttttatgaa agtaacttcg cttatgtcac agtccctttc taaataggca acctatacga
     4741 attctgcaag aaacttaacg aattttgcaa aatgtccttt aaattagatc tttcattata
     4801 ataaggtaca catactgtct tagggggaga actaatgaaa attcatttca ataaggactt
     4861 ttggcggaat ggtttctttt atatatactt attacttttg tttctctgga ttgctccatt
     4921 ttcagatggt tcggttccat gcttgcaatt atgtttaata aagactgaaa aaaggctcca
     4981 acagcaatgt tcggagcctt ttatgcattc cacaaattat agtattcttg atgatgattc
     5041 aaaagttcct ggtgagtacc ctgttcaatg atttttccgt cgcgcattac taccacttta
     5101 ttgactttct tagcaatcga aagacggtgg gcaataaaaa tcattgtgca gtcttcaatt
     5161 tcaagcaaat tctcaacgat tcttttttca gtaattggat ctaagctact tgttgattca
     5221 tcaaaaatta aaacacgcgc agaagttagg agtgctcgtg caatcgtcaa gcgttgtttt
     5281 tgaccaccag ataatgcagt tgcttcttca tctagttttg tttcatagtt taagggcatc
     5341 tcttgaatat cattatagat taatgccaat ttacatgcat tatcgatttc ttcagcagat
     5401 acttcacggt ctaatcccat tagcaagtta tctttgattg ttcccgaaaa taattgtggc
     5461 aattggggta agtaatgcac atattgtcta atatcgcaaa gattaatctc tgttgtctta
     5521 tgctgattaa attctatctg cccttgagta ggtaaataaa agccaactaa caactttgcc
     5581 aaggtcgatt taccagaacc gctcaaccct acaattgcca atttatcatt acaaccaatt
     5641 tgaagattga tatcttgtaa aattggatga ctatattcat atgaatagtc aacatgttga
     5701 atgtttatcg gccctattaa atctgtttga tcctgagaat tcgtatctga cttttcggta
     5761 tcaacttgca gaacttcatt caatcgatta ttcgctactt tagcttcttg gagtttaggt
     5821 tgaagattaa taatattttg caacggactg acaaaaaagg ctaataatgc attaaaggcc
     5881 atcaatgtcc caatacttaa tcggtcttga attaccaaaa ttgctccttg aaaaagaatg
     5941 attgttacta aaccgtattg aatccacatt ttaattgcat cctgaaaaga tttagtttta
     6001 acatatgtta gattctttcg taaaaaatcc gcaaattgct tttcaacatt tttataacgg
     6061 atattttcaa gttgcagcac tttcaacgtc tctacgcctt ttaaatcctc aataattgca
     6121 gaacttaatt gagcattact ctccatctgt tcctgatcaa gtttagcaaa gcgcttatta
     6181 aaggcataaa tgataatgac ataaatcgga atggtactaa ttgtagttaa aaataatgac
     6241 cgatcatata aagaaagaac aattcctata atcaccatca cgccaacgtc taagaacatt
     6301 gaaataatag tgcttgataa ggcatcaata atcttattaa tgtcattaaa ccgtgaagta
     6361 atttctcccg tttttcttgt ggagaaaaat cgcatcggta gacgataaac atggtgaata
     6421 tatctaagac ttatttgtga tgtcagtttt tgatccagcc tagtcaaaag aacatcccgc
     6481 agataattaa aaagagaatt aaacacatac actactaata aactaccagc aaggatcgtt
     6541 aagccattaa tatttttcga gggaataaac cgatcaataa ttaattggag atagtatgaa
     6601 ccgacgatgc tgatgaaagt aattagcatt gccgcaataa caattccgga tatatctttt
     6661 ttataattag ttaattgttg aaacatcgtc gttaatccag ctaaaggttc tttttgcggt
     6721 gtatacccct tagcaggcga aaaaagcaaa catacgcctg accataaacg atcaaattca
     6781 tcccgcgtca ttttttgtac tttcgtagca ggatctggat cagctacata gatgtaatct
     6841 tgatcagcct taaagacaac acagtaatga agtaaatcat ccttaatcac atgcgcgatc
     6901 aatgggtaag taatttcagg atcatcaaac aatgatatat ctgcttgaat gggtataacg
     6961 tctaatccaa gatgctttgc tgcttttaca agtcctaagg cggtagttcc ttgcttagtc
     7021 gtccgggcta ggtcacgtaa ttttgcgatt ggataaacag agccaaaatt gcgcaaaatc
     7081 atcgctaagg aggcaacccc acaatctgct tcatcaactt gggctacata atgaagataa
     7141 ttgattttca ttcaccttac tttctaatca gacaaagaaa taaagtccaa aattaataat
     7201 gattctgggc tttatattct tataaaatac tatttatttt taaatatggt taataaagta
     7261 gcaattattg ctccaactaa gaaaactaag cagtaagtaa attcataacc attttctaca
     7321 tctattaacg gtttaatcca aagaacaata aataacatgt aaaaataaaa attaaaatct
     7381 ttgtaaaatt gtttattaat tctcactttt accatcttct cctcttatta gtggaatgga
     7441 ctatcatgat agcctgcgta acacgattga gcccatttgt tcagggaatt aacaatatct
     7501 ctaactagtt cattaacctg tgaagagaga ctccatcctc cagaaacctt gcttaattca
     7561 tcaaagttta atttacgata agtcatttta attacctcct gatacgataa agttaggatt
     7621 ccaacattag tatataagta aaaatttttt ctgtgtcatt ttgcaaaatt cgtaaacctt
     7681 tctgcagaat tcgtagtaaa aaagcgaaaa cgtttactaa aatcgcttga taataaaaag
     7741 aaactatgac agcttttttt gtcacagttt cttttgaact ttataaaccg ttattatcct
     7801 tttcaagaaa attaactaat gattttattt ttcggtaact aacagttatc ttaatttcct
     7861 gattttcatc aaagtaaacc acacgttctt tacgattaaa ttctcggatt gctttaggat
     7921 taatcagcgt actttgattt actttcaaca aatgcttgtt attaacttga cctaactcgc
     7981 cacgatattc aatccgaata tcttttccca caatccgtaa ccggcgattt gtgtttttta
     8041 ctgattcaat ataatagagg ttttcaaaat caacttgcct ttttactcca tgagtcggtt
     8101 cataagtaaa cttttcttga tgtttttgat tactgttcat gtaattctga tagcgagcat
     8161 atgcttcatc aatatctgtt cggagccgat ccgcaatcga ctcaatctgc tctccctttg
     8221 atatatagtc gaatggttca atccggtgcg aaacagtata aggtaagtat tcttgatatg
     8281 cagttataaa gataatttcc gcaaattcag cttttttgcg gatctgctca gcaacatcga
     8341 tcccactaag ttgattctct agctcaatgt ctaaaatcgc taaataaacc tcatctttga
     8401 tgctatcaat cacttcttgc ggatcatttg tccgcaaata taattctatg tcataactat
     8461 ttggagtagc gttaatcaat tttcgctgag aaactagacg ctcagtataa tcagcttgat
     8521 aatcatcatt ttccaaaata attactttta acattttatt ctcactttcc ctgaataaaa
     8581 caagtcatca taattacctt atctttaact tccgctgaaa aagaataatg gtcatcattt
     8641 tctactaact gggtcacatt tgaaagccca atcccttgat gtccttcctt ggtcgaatgc
     8701 tcaaatttca gtgcagtatt aatattaagt ttttgttcaa tcgaattagc aattaccaat
     8761 tcataaactt ctggactgtg cttaagcaat gcaaactgaa tatatggttt ggcttgtttg
     8821 aaggttgctt caattgcatt gtccattaaa attccaataa ttctagcagt ttttatttct
     8881 gaacccggta actcgtcaat ctcagcatta acttcaaacg aaaatggaat acctttttcg
     8941 actattttat aagccttttc cttaataaga ttatgcaacc ctgaaatttt aatcttatct
     9001 aaagcattat caatttcatc ataatgcttt tcaagtgtat cattttgaag aaacgttgct
     9061 agcaattttt ctgcttcctt atctttgtga tcacgaatat atccttgaac actgagaagc
     9121 atattgcgtg tatcgtgacg ttcacgccga atttcattgt attgttggtt cagctgattg
     9181 gcactggcaa tttgcgcttg atatttatcg atgatttgtt gctgtcgttg tgtttgctga
     9241 ctacttttaa cgaaattaat aaatccggtt gcacacacta cgataattat caaatacatt
     9301 attaacaaca gcgaggcata cttatttgct accccgtcct tttcggcaat agcagttaac
     9361 cacacataaa gcatgaacaa aattgccgta atttgccata accctatcgg tcgaggaaaa
     9421 ttaatcctaa tccatctcag tttgggacga actactttaa ctgctaagat tgcaactaca
     9481 atagttatga ttaaatcatt aattggaata agccatccta aaagtgctat atctgtcttt
     9541 ccttgtaaaa aaacgtataa gtatagtgat ctactaaatc gaataaagat gccattacaa
     9601 tactaataca catcgcaaga atactattta taactatata agaattagat tttattctgt
     9661 caactaacca aaaataaaat actataagta ctgggtatag cgatcctaac ataaaaaata
     9721 ctattgaaaa aaatataatc atcaagactg ctaaaaaatc aattattact aatcctaatg
     9781 aaaagtcgct agttaccaat tgatatatta atattatttc aataatattt aatatagatg
     9841 acgttaatcc ttgtcctaca gttaaatgaa tcatctttta atccaattta aaactgctct
     9901 ttcccatgaa cgaggacttt taaaggcaag tgaatatccc caaccaccta atactttaga
     9961 taattctttc cttgataaaa atttatatga tttttttaac ataattacct ccaataaata
    10021 acaattacct atttaactac aaattcagca atattagcca aaactaacat tcccaaaaac
    10081 actaaaaaat tcagtggccc tgcatgcaaa atacaataca aggcaatcaa tccgatataa
    10141 aaaaggttaa tgattaccaa atttttcttc gtttctaaat ccaaatccac catataacta
    10201 actcctactt tatccatccc tctgataatg caaaagaaat aataattgtt aaaacaaagc
    10261 aagctattgc aatcataatt gcgcgttcag cactcgggcg cacaacatct cctcctttag
    10321 tagataacca caggctcatt tttatgtaag tcactaaaag cttgaccagc tacatctgga
    10381 tgcatgttaa tacaaccgtg cgatccaccg cctttagcaa gataagcctg ttttgaccaa
    10441 tcgtgacgcc aacttgcatc atgaaatcca catccactat cagtaaatgg tgaccaatat
    10501 tgaactttgc tagcgtattt cgaaccgtca tcgttaaggc cccgaagaac agacggtgtt
    10561 tgctggtaca tgatatacca gacacccttc ggcgtctcgt tatctttgtt attggtccca
    10621 ctaacaatgt cagtgctaag aacacattta ccattcttat agaaccacgc atgttggtcg
    10681 gctaatgaaa cttcggcgta agtgtcccct atgccgttgt tacttgtggt attataccca
    10741 gttccttgtt gattataacc cttaccataa atatcatttt ttgcatttac tgtttgctta
    10801 ttttcaatca atgcattcgt aagagtcttt ccagcttgtt tcttactgat cttccaacca
    10861 tatgaaccag catctgttgt tttgatcact gatccatcat gtgttttgaa ttcaaatgat
    10921 ttgccaagag ttgcttgggt attattaatt tcatcaatct ttgaattagc tgctccagtg
    10981 tcaaagtgat attttccatt ttgatatgtt gctctggtaa taatctcacc acaatttaat
    11041 tgatactttt tgttttgtac ttggtatgtt acagatcgtt ttgataattc ttcgagcttt
    11101 gctttttcat tctgaacagt tttactattt gcagaaagcg gagtcgtata ttctggcttc
    11161 agatgaattg ttccaccagc aatctcattc tcaactttat tatgcaaacc atctaaactg
    11221 tattgagtac caccaactgc tggttttact tgtactcggc cattttcgta tacagcgtaa
    11281 gcatcaacag gagcttttcg accattattt aattctgtta ccttttgact gactgcttga
    11341 tcaatctttg atacttcatc ttgattaaca ttttgaggct taatcgcaat gttctttgcc
    11401 ttagatgatg ggaagaaagt atactgacta tgtaatgcat ttttaatttt ttgttcgtca
    11461 gcactactaa actttgctac tgattgctta tccgtaaata ctaactcatt gttaacataa
    11521 atttttggcg attgtggatt atcttgtaac ttctttaatg cttgtttagc agtcaatcca
    11581 ccaaccgaca cattatcaat cttaacgttc ttattaaaat gacgacgctg gtgaatagtc
    11641 atgcagccaa ccaccagcac taataagcac aatgtaatta ttattagttg tttaatagat
    11701 agtttttgca taaaagtact cccataacat ccaaatcttt aagtctaatt tctatactaa
    11761 ataaacatat tcattacgct cattcattat atactaaagc gtaaacaatt agtatatttt
    11821 acatttttca tagtgttttt actaaaaaag cgtctggcaa aaataccgga cactttttag
    11881 taaccaaact atttagcggt tgtaacttga tattgattat tacccttagc tttgtagtaa
    11941 atagtttgac cgttgtaggt tacagaacca ttaccttcct tggcattttt gtaaaactct
    12001 tcaacagatg tattgttatc aatcacgccc gctttttgcg cagcccggta gctaaagttc
    12061 atcccgtctt ccactgttac aggttgttga gttgatgcag cttgagttgt ctttcggctt
    12121 cctgtccgcc ggttgtttgc gttggcgaca c
//
