LOCUS       c00044_JAJGTN0..       15337 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGTN010000070.1 Limosilactobacillus reuteri strain R.n.1-B
            scaffold70, whole genome shotgun sequence.
ACCESSION   JAJGTN010000070
VERSION     JAJGTN010000070
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 17:59:17
            Original ID  :: JAJGTN010000070.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15337
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15337
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3472:9940]"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3473..9940
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
     cand_cluster    1..15337
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /kind="single"
                     /product="Nitrate_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15337
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Nitrate_reductase"
                     /region_number="1"
                     /rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /tool="gutsmash"
     CDS             complement(74..448)
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="MLERKEHKKMYKSGKNWAVVTLSTAALVFGATTVNASADTNTKNN
                     DSSTIQVTIGDNDIAVKSVTLGSGQVSAASDATIKNSANANSASSAANTQNSNSQVASS
                     AATTSSTSSAASCAPGMGIS"
     CDS             885..1739
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="MLYNAALVLEGGAFRGQYTAGIVDTFLAHHIEFRSVIGVSAGSLC
                     GVNFVSKQYGRAANININHRHDRQYISMARVFKKQIINLDYLFEDHGYSWQNFNEAAYR
                     RSASHFTAVATSVKTGKTVLFTDPVGEELTNALKASSSMPFLSDPQETSQGPCLDGGVT
                     DSIPFDIAQQQGYDKIVVVRTRDVNYRKKPSSSAVKKLYDMVYKDYPEFAKAGINRPLL
                     YNQQIAEINRLSREGKIFNIAPSKPIKIKRIEGNIKKIRALYETGRKEGEEIVPALVDY
                     LAN"
     CDS             1756..2403
                     /locus_tag="ctg44_3"
                     /transl_table=11
                     /translation="MSTKKRVYIPKNKTNGQIKGKRKIWVENVKFLTLEEYDQLRETIK
                     LHSRPELVNRNLLLIAIALNNGLRASDVVTLRVGHVLNKTKTRVIEQKTGKAKTLFWNN
                     CLAEIIDYLNDLDYKDENDYLFPGKQEGHFSVHGFYEMLQRMARKTENNKIVAKIGTHS
                     FRKTFGRQLYKKGVNVEIISQLFNHSSERNTRHYLGIEQEDLDKVVQNFKFE"
     CDS             2512..3402
                     /locus_tag="ctg44_4"
                     /transl_table=11
                     /translation="MNIKSVPKKQLWGIELNLISLLFSSISPVLNKFSLTSLSPVVGGI
                     FTSAFAAIFTFATILITHQHVSLTNLKSLWLWLLGGTNAIGIILQYIALSTLSPITVTL
                     IARMYLVYVFFLSYIFLKEKITKWDYLAIILCILGSFFISGSRLQFSDNLLGLICAFIY
                     PLMYAANNIVAKYLVSDEEPNNVLFFNHFTSALLLFCYALIIGTSFSHISSQAVAFNFG
                     GAFFNGFMSLLLFYTSLQFITAGKANIVRAFGPVIVIIYSSFFFPVQVTPSLVLGAILV
                     ILASTIVTFTRTNYE"
     CDS             complement(3473..4162)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_gam"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_5"
                     /sec_met_domain="Nitrate_red_gam (E-value: 1.2e-77,
                     bitscore: 250.4, seeds: 140, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNGWSIFLWVIYPYIMLASFFIGTFVRFKYFHPSITAKSSELFE
                     KKWLMIGSVTFHIGIILAFFGHCLGMFIPASWTAYFGITEHMYHIFGSLMMGIPAGILA
                     FVGIAILTYRRMTCSRVYKTSDINDIIVDWALLITIALGLACTITGAFIDYNYRTTISP
                     WARSLFVLNPQWQLMRSVPLIYKIHVLCGLAIFGYFPYTRLVHALTLPWQYIFRRFIVY
                     RRRARVY"
     CDS             complement(4155..4733)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_6"
                     /sec_met_domain="Nitrate_red_del (E-value: 1.6e-09,
                     bitscore: 28.0, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIDFRRLTDLKDTFAVLSRLIDYPDTETFSPEIRQLLLADNALST
                     ATRGELLSLFDELAALSSIEVQEMYAHLFEMNRRYTLYMSYYKMTDSRERGTILARLKM
                     LYEMFGISEATSELSDYLPLLLEFLAYGDYTNDPRRQDIQLALSVIEDGTYTLLKNAVT
                     DSDSPYIQLIRLTRSLIGSCIKMEVQEDA"
     CDS             complement(4726..6285)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_bet_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_7"
                     /sec_met_domain="Fer4_11 (E-value: 3.3e-39, bitscore:
                     123.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00052, bitscore: 10.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_bet_C (E-value: 4.1e-28,
                     bitscore: 87.1, seeds: 110, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIKAQISMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNVE
                     TKPGVGYPKRWEDEDQYHGGWTLNSKGKLKLRAGSKLNKIALGKIFYNNDMPELDNYYE
                     PWTYDYKTLFGPEQKHQPVSRPKSQITGEGMELTTGPNWDDDLAGSTEYVQQDPNMQKI
                     EGDIKNNFEQAFMMYLPRLCEHCLNAPCVASCPSGAMYKRDEDGIVLVDQERCRGWRFC
                     MTGCPYKKVYFNWKTHKAEKCTFCYPRIEEGQPTVCAETCVGRIRYIGAILYDADRVEE
                     AASTPDESKLYEAQLGLFLDPNDPEVVKQALKDGISEEMIEAAQKSPIYKMAVKEKIAF
                     PLHPEYRTMPMVWYIPPLSPVMSYFEGRDSIKNPEMILPGIDQMRVPVQYLASLLTAGN
                     VPVIKKALYKLAMMRLYMRAKTSGRDFDSSKLERVDLTEERATSLYRLLAIAKYEDRFV
                     IPSSQKAEMEDAQTEQGSLGYDECEGCALAPQHKSMFKKAEAGKSTNQIYADSFYGGIW
                     RD"
     CDS             complement(6275..9940)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molydop_binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_alph_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_8"
                     /sec_met_domain="Molybdopterin (E-value: 5.4e-142,
                     bitscore: 463.7, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 1.2e-23,
                     bitscore: 73.4, seeds: 74, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_alph_N (E-value: 1.1e-08,
                     bitscore: 25.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSRFFNKVDKFNGTFTQLEENSRRWEKLYRQRWAHDKVVRTTHG
                     VNCTGSCSWNVYVKQGIITWEHQATDYPSCGPNIPGYEPRGCPRGASFSWYEYSPVRIK
                     YPYIRGKLWELWTAAKEEHENPLDAWASIVEDPEKSKKYKKVRGHGGLIRVHRYEALEM
                     ISAACLYTIKKYGPDRIGGFTPIPAMSMMSFSAGARFIALMGGEQMSFYDWYADLPPAS
                     PQVWGEQTDVPESAEWYNSSYIIMWGSNVPLTRTPDAHFMTEVRYKGTKIVAVSPDYAE
                     NVKFADDWLAPEPGSDSAVAQAMTYVILDEFYQKHPVKRFIDYSKRFTDLPFMVELEPS
                     TANGDHYTPGRFVRISDLVDDDTIVNPAWKTVVYDQNNHKIVVPNGTMGQEYNAKEKWN
                     LELLDQNGNKIDPALSINDQDGETEQIVADFPAFSNDGNSVVQRHLPVKKLKFTDGKEH
                     LVTNVYDLMMAQMGINRTGNDELAAKDAMDAKSYFTPAWQESRSGVKAEQVIQIAREFA
                     QNAAENEGRSMVIMGGGVNHWFNADMNYRNIINMLMLCGCVGMTGGGWAHYVGQEKLRP
                     QEGWANITFANDWEKGGARQMQGTTWYYFATDQWRYEEIDNQAQKSPVWKSKHSYLHNA
                     DYNQMAIRLGWLPSYPQFDRNPLSFAKDYNTTDINEISKKVVDELKKGSLHFAAEDPDA
                     NQNQPKAFFLWRSNLFASSGKGAEYFMKHLLGAENGLLAKPNDRVKPQDMIWRDKGAIG
                     KLDLVVDMDFRMVSTPMYSDVVLPAATWYEKKDLSSTDMHPFIHPFNAAVSPMWESKSD
                     WQQFKLLAKTVSEMAKKYMPGTFYDLKSAPLGHNTQGEIAQPYGEIKDWKNGETEPIPG
                     KTMPSLKLVTRDYTKIYDKYITLGPNIVNNYNYKVDDQYDYLKDMNGIASEGIGAGCPL
                     LDEDEKVCDAILRMSTASNGKLADRAWEKKQERTGEHLTDIGRGHADDSMSFKQITAQP
                     QEAYPTPIGTSAKHGGARYTPFSLMTERNVPTFTLTGRQHYYLDHEIFREFGENMATYK
                     PSLPPVVMAPGDVDVPPVKDEVTLKYMTPHGKWNIHTMYYDNLEMLTLFRGGPTIWISP
                     QDADKIKVKDNDWIEVYNRNGVVTARAVVSVRMPEGSMYMYHAQDNEIYEPLSTITGNR
                     GGSHNAPTQIHVKPTHMVGGYGQLSYGWNYYGPTGNQRDLYANVRKLKKVNWSED"
     CDS             10085..11104
                     /locus_tag="ctg44_9"
                     /transl_table=11
                     /translation="MNRYDRQERVHQIGSIGQQKISHATIMIVGVGALGSYTAEQLVRA
                     GVKRLVLIDPDTVDVTNLQRQSLFTEEDASKQRLKVEAAKEHLHKINSACQITAIPAPI
                     TADLIDEYQFTLCLDCLDNYQARDLLNKLAIIKNFDYLFASCAGTYGNVMAISPQNHPC
                     LNCLFPNINELKQNDCDLIGVNTALIPIVAGLQVSLALHYLVDKTQVNFNELITVDNWS
                     MQFSKFAINKNHHCPACAKPSSISLEEESGPELHMLCGENAYYTVKEKPINFGRLKEFL
                     AKKELLINANRLFLHFKWENRPVSIFKNGKIVMYDLPTSAIAQKQFKSLNILMKEDLL"
     CDS             11101..11598
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_10"
                     /sec_met_domain="MoCF_biosynth (E-value: 6.1e-34, bitscore:
                     106.9, seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIAILTVSDSRTLDSDTSGKLIAMKMANAGLSVVDRVIVNDDI
                     VNIQTAYLQLEQQALDIIITNGGTGIAQRDVTIPAIRPLLKRLIPGFGEAFRQISFEEI
                     GTRALASQALAGFNFRNQLTYCLPGSQNACQTAINKLILPEYEHLLFESSSQRKEVHHH
                     AH"
     CDS             11588..12055
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_11"
                     /sec_met_domain="MoeA_N (E-value: 1.3e-32, bitscore: 102.8,
                     seeds: 1302, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRRIPISVAEAQKKINEISLKTATETIPLSEANHRVLAKDVHA
                     HYDYPHFRRAGMDGYAILASDDHDFPREFNVRGEIQAGATWDQPLQSGDAVRIMTGAYV
                     PSDVGKVIRIEKTRPAKDENKVQIITTESKTNITEAGTDVTRLTLRKLVLM"
     CDS             12247..12840
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_12"
                     /sec_met_domain="MoCF_biosynth (E-value: 4e-17, bitscore:
                     52.3, seeds: 114, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_C (E-value: 4.4e-14, bitscore: 42.7,
                     seeds: 41, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKNLVEETGGIVDFETQLPDDADLIKQTLEEQIATHEIVITDGG
                     VSVGDFDFIGDEARKADELLFNKIKQRPGSVTTAFVQNSTLIMALSGNPGACFTGFYLY
                     MEPLIRRYQHQVSRIKQVRAILTAPYNKTNGFDRYLRCTYKFKDNQFYVYPNGINRSGS
                     LANLQTTTCLALIPHSTTPMKVGTETDAWLLPFK"
     CDS             12819..13310
                     /locus_tag="ctg44_13"
                     /transl_table=11
                     /translation="MAITLQIIGHKKSGKTLITTTLIERLSKEGYRVAALKHDAHNAAM
                     DVPTTDSARMSSAGAKQVILQSATEFFFHQKSNVPSLTEMVELLSTDNDFILIEGHKEA
                     TQYPQILLLKPGEDSTNVAHTPPLKTGSIFNGTTADLLGKDAIVNWCYDYLKQVKGDAE
                     "
     CDS             13307..13879
                     /locus_tag="ctg44_14"
                     /transl_table=11
                     /translation="MIGLVYAGGKSTRFGKDKATYHVPGLPATNIELAVEKLTPLCQQI
                     VVCANEINRAHILKLVGQEPAVQIICDIPPYDHHGPLSAIIACTNQFSIVQDYLTLAVD
                     YPYITKNSLAVLARTPNSYIATSQHNHYSLAHFSVSNEQVTTWVDNNDDWRLRSFITNK
                     CVCHPLTYRSSNEFSNLNYREVDLNEK"
     CDS             13869..14153
                     /locus_tag="ctg44_15"
                     /transl_table=11
                     /translation="MKSKDSMTNPDFQKLISLVLNDLTIRRTMLENREQEVSQQMSSLE
                     KDAELEQLDDQIQQIQADFDHYREFQDPEFDFSATKYFQGPSMGLPRHP"
     CDS             14304..15254
                     /locus_tag="ctg44_16"
                     /transl_table=11
                     /translation="VLETANWIQKYFNQSPDAIFLFKNDDLLVSNEPAQRLVTMLNLDV
                     NYLLQIGKNAWSQLENDDCASCLIKKRLKEAAVPITFHSNATHPFHFSMVYRPLDDKEN
                     VFALTLENREQQQRLSQVEEHRILNQYVNEAHEKERQKISQDLHDSVAQGIYAAIMGIQ
                     RLATVQNQRNTEQFQSMSAAIEKQLQTTLKEIKGLALDIRPSVLDNFGLIPAIKALAKR
                     LQNSTGITIDVIALTSAEKLQKNIQNVLYRITQEAINNAIKHAHSTEISIIVTDHSSYL
                     QLEILDNGIGFDIDQHSGFNGHSLGLMNMNRVGDN"
ORIGIN
        1 ccacctcaca gtggacaccc ttgtcctcag ctcatggttc cgactactac ggtccatagc
       61 ggactctcac cgcctagcta atacccatgc cgggcgcaca tgaagctgcg gaacttgtag
      121 atgatgttgt tgcagcagaa cttgctactt gactgttaga attttgtgta ttagcggcag
      181 aagaagcact atttgcatta gcagaatttt taatagtcgc atcactagct gcactaactt
      241 gaccactacc aagtgtcaca cttttaacag caatatcatt atcgcctatt gtaacttgta
      301 tagtagaaga atcattattt ttagtattcg tgtccgcgga tgcgtttaca gttgttgcac
      361 caaacaccaa cgcagcagta gagagtgtaa cgactgccca atttttaccg cttttataca
      421 ttttcttatg ttccttgcgt tctagcatag aaataacccc gtttctttac cttttttgct
      481 aaacgtttaa caattaactg tgcactattt tattatgatt atcttaaatt atcaatagtt
      541 tcttcataaa aagttcatat ttaaatattt actcattttt ttgatagcaa tatgcgtttt
      601 tcttctgaga cgaagtgtaa cgatctacta ctcatcaaaa ttaatttcag ttcgtctgag
      661 aggcaaaagc tgtttttacc cctatttttg tattatttta aaattagtaa gactcttttg
      721 ataaaagagt cttacattaa ccgagaataa acgttgatat aacaagcttt taaaatccta
      781 tattttcgcg taagactgtt gtataatttt attgaaaaag tgtctcacta aaaattaggt
      841 catttttgct atttttggca gacaaaaagg agttatttca ttttatgtta tataatgcag
      901 ctttagtttt agaaggtggc gcattccgtg gccaatacac tgccggaatt gttgatacat
      961 ttctcgctca ccatattgaa tttcgaagtg taattggcgt ttctgctggt tcgctttgtg
     1021 gagttaattt cgtctctaag caatatggac gcgctgctaa tatcaatatt aatcatcggc
     1081 acgatcgcca atatatctcg atggctcgtg tatttaaaaa gcaaataatt aatcttgatt
     1141 acctttttga ggatcacgga tattcttggc agaattttaa tgaagcagcc tatcgacggt
     1201 cagcatctca tttcacagca gtcgctactt cagtaaaaac aggaaaaaca gttttattta
     1261 cggatcctgt cggtgaggag ttaaccaatg ccctcaaagc ttcctcatca atgccatttc
     1321 tttcagatcc acaggaaaca tcccagggac cttgccttga tggtggggtc acagattcaa
     1381 ttccatttga tattgcacaa caacaaggat atgacaagat tgttgttgtc cggactaggg
     1441 atgttaacta ccgaaagaaa ccctccagtt ctgctgtaaa gaagttatac gacatggtat
     1501 ataaagatta tcccgaattt gctaaagcag ggattaatcg tccccttctc tacaaccaac
     1561 agattgctga aatcaatcgt ttatctcgtg aaggaaagat ctttaatatt gctccctcta
     1621 aaccaattaa gattaagcgg attgaaggaa atattaagaa gattcgagca ctttatgaaa
     1681 ctgggcggaa agaaggagag gaaatcgtcc ctgctttagt tgattacctc gcaaattaac
     1741 aaaggaagaa atattatgtc aactaaaaaa cgcgtttata ttcccaaaaa taagacgaat
     1801 ggtcaaatta agggtaaacg gaaaatatgg gtagaaaatg ttaagttttt gacccttgaa
     1861 gaatatgatc agttacgtga gacaattaaa ttgcattctc gtcctgaatt ggttaatcgt
     1921 aacctattac taattgcaat tgccctcaat aatggattac gagcatcaga cgttgtaacg
     1981 ttaagagttg gtcatgttct aaataaaact aaaacccgtg ttattgaaca aaaaactggt
     2041 aaagctaaaa cgctcttttg gaataattgc cttgccgaga ttattgatta ccttaatgac
     2101 ttagattata aagatgaaaa tgattacctt ttccctggaa aacaagaagg ccatttttct
     2161 gtacacggct tttatgagat gcttcaacga atggctagaa aaacggaaaa caataaaatc
     2221 gttgctaaga ttggaacaca ctcttttaga aaaacttttg gtcgacaact ctataagaaa
     2281 ggtgttaacg ttgaaatcat ttcgcagtta tttaatcact cctctgaacg aaatacgcgc
     2341 cactacctag ggattgaaca agaagacctt gataaagttg ttcaaaattt caaatttgaa
     2401 tagttattat tctgaatatt atgtaaacta aaatatttag tcattttcct aatagactta
     2461 ggaatataat tcattagaat taaagtaata aaaagtattg gatgtgacta aatgaatata
     2521 aaaagtgtac caaagaagca actatgggga attgaattaa atctgatttc tctcctattt
     2581 agtagcatta gtccggttct taataaattt tcacttacta gcttgagtcc ggttgttgga
     2641 ggaattttca ctagtgcgtt tgctgcaatt tttacttttg caacaatcct cattactcat
     2701 cagcatgttt ctttgactaa tcttaagagc ctgtggttat ggcttttggg tggaacaaat
     2761 gcaatcggaa ttattcttca atatattgct ctctcaacct taagtccaat cacagttacc
     2821 cttatcgctc ggatgtattt agtttatgtt ttcttcctat cttatatctt cttaaaggaa
     2881 aagattacaa agtgggatta cttagcaatt attctttgta ttctcggttc tttctttatt
     2941 tcaggaagcc gacttcaatt tagtgataac cttcttggat tgatttgtgc attcatctac
     3001 ccactaatgt atgccgccaa caatatcgtg gctaagtatc tagtcagtga tgaagagcca
     3061 aataatgtct tattctttaa ccattttact tcggctcttt tacttttctg ctatgctctt
     3121 ataataggaa cgtcatttag ccatatttct agtcaagcag ttgcatttaa ctttggtggg
     3181 gccttcttta atggtttcat gtcactactt cttttctata ctagcttgca gtttattacc
     3241 gctggtaaag caaatattgt tcgtgcattt gggccagtaa ttgttattat ttactcttca
     3301 tttttctttc ctgttcaggt aactccttcc ctagttttag gagctatttt agtaatttta
     3361 gctagtacaa ttgttacctt tacaagaaca aattacgaat aatcgcaata taaaagcatc
     3421 agaatttccc tgtaaagaaa tctgatgctt ttattatatc ttctcctata tattaataaa
     3481 ctcttgcgcg ccgacgatag acaataaaac gacggaaaat atattgccaa ggtagtgtta
     3541 aagcgtggac caaccgggtg tatgggaagt aaccaaaaat tgctaatcca caaagaacat
     3601 gaattttata aattaatggc actgaacgca tcaattgcca ttgaggatta agaacaaata
     3661 ggcttcttgc ccatggacta atcgttgttc gatagttgta atcgataaat gcacccgtaa
     3721 tagtacatgc tagacctaat gcaattgtaa tcagtaaagc ccagtcgaca ataatatcat
     3781 tgatatcact tgttttataa acacgagaac aagtcattcg tcgataagtc agaatcgcaa
     3841 ttcccacaaa tgcaaggatc cctgctggaa ttcccatcat caatgaccca aagatgtggt
     3901 acatatgttc agtgatccca aaataagcgg tccaacttgc tgggataaac attcctaagc
     3961 agtgaccaaa gaaagctaaa ataattccaa tgtggaaagt aacgcttccg atcattagcc
     4021 atttcttttc aaaaagttcg cttgatttgg cagtaattga gggatggaaa tatttaaatc
     4081 taacaaatgt tccaatgaaa aatgatgcca acattatata tggataaata acccataaga
     4141 aaattgacca gccattatgc atcttcttgc acctccattt taatacacga accaattaat
     4201 gaacgtgtaa gcctgattaa ctgaatatag ggactatcac tatctgtcac tgcatttttt
     4261 aaaagggtat aagttccatc ttcaatcaca cttaatgcta attggatatc ctgacgacgc
     4321 ggatcattag tataatcgcc atatgctaga aattctaaca atagaggcaa ataatcagaa
     4381 agttcactgg tcgcttctga tataccaaac atctcatata gcattttcaa ccgtgctaaa
     4441 atggtccctc gttcacggga atcggtcatc ttatagtatg acatataaag agtataacgt
     4501 cggttcattt caaaaaggtg agcgtacatc tcttggactt cgattgaaga tagtgcggct
     4561 aattcatcaa aaaggcttaa taattctccc cgcgttgcag ttgataatgc gttatccgca
     4621 agtaataatt gacgaatctc tggtgaaaac gtttctgtat caggatagtc aatcaaacgg
     4681 gaaagaacgg caaatgtatc ctttaaatct gtcaatcgtc taaaatcaat cacgccaaat
     4741 ccctccatag aaactatcag cataaatctg attagttgat ttgccagctt ctgccttctt
     4801 aaacatactc ttgtgttggg gagctaatgc acagccttca cattcatcat agccaagact
     4861 accttgttcg gtttgtgcat cttccatttc tgccttttgg ctacttggaa taacaaagcg
     4921 gtcttcatat ttagcaattg ccagtaaacg ataaagtgat gttgcccgtt cttctgttaa
     4981 atcaactcgt tctagtttac tgctatcaaa atcccgacca ctagtcttag cacgcatgta
     5041 tagccgcatc attgcaagtt tatataaggc tttcttgatg acaggaacgt ttccagcagt
     5101 taatagactt gccaagtatt gaacaggcac ccgcatttga tcaattcctg ggaggatcat
     5161 ttcaggattc tttattgagt ctcgtccttc aaagtaactc ataactggtg atagcggcgg
     5221 aatgtaccaa accattggca ttgtccggta ttctgggtga agtgggaagg caatcttttc
     5281 ttttactgcc attttataga tcggtgactt ttgtgcagcc tcaatcatct cttcagaaat
     5341 gccatccttg agtgcttgct tgacaacttc aggatcgttg ggatcgagga ataagccaag
     5401 ttgtgcttca tacagcttac tctcatcagg agttgatgct gcctcttcta ctcgatcagc
     5461 atcgtataga atagcaccaa tatatcgaat tcgaccgaca caggtttcgg cgcaaactgt
     5521 tggttggcct tcttcaattc gcggataaca aaaagtacat ttttcagcct tatgagtctt
     5581 ccagttaaag tagaccttct tatatgggca tccagtcatg caaaatcgcc atcctcgaca
     5641 gcgttcttgg tctactaaaa caatcccatc ttcatctcgt ttgtacattg cacctgatgg
     5701 acaagaggct acacaaggcg cattcaaaca gtgctcacat aatcggggaa gatacatcat
     5761 aaatgcctgc tcaaagttat ttttaatatc cccttcaatt ttttgcatgt taggatcctg
     5821 ttggacatac tcagttgatc ctgctaagtc atcatcccag ttaggaccgg tggttaattc
     5881 catcccttcg ccagtaattt gcgacttagg acgagaaacg ggttggtgct tttgttcagg
     5941 accaaataat gtcttatagt cataggtcca tggttcgtag tagttatcta actctggcat
     6001 atcattattg taaaaaatct tgccaagagc aattttattt aatttgcttc cagcacgtaa
     6061 ttttaatttg ccttttgaat taagggtcca tcctccatgg tattgatctt catcttccca
     6121 gcgctttgga taaccgacac ctggcttagt ttcaacatta ttaaaccaca tgtattcagc
     6181 gcctgggcga ttagtccatg tattcttaca agttactgaa caggtatgac aaccaataca
     6241 cttatcgagg tttaagacca tgctgatttg tgctttaatc ttcactccag ttcaccttct
     6301 tcagttttct tacatttgca taaagatcac gttggtttcc agttggtcca tagtaattcc
     6361 aaccgtaact caattgtcca tatccaccaa ccatatgcgt tggcttaaca tggatttgcg
     6421 ttggtgcatt atgcgatccc ccacgattac cggtaatggt agaaagaggt tcgtaaattt
     6481 cgttatcttg ggcgtggtac atgtacattg acccctcagg catccgaaca gaaacaaccg
     6541 ctcgcgcagt aacaacccca ttacggttat aaacctcaat ccagtcatta tcttttacct
     6601 tgatcttatc ggcatcttgg ggactaatcc aaatagttgg accaccccgg aataatgtca
     6661 acatttcaag gttatcgtag tacatcgtat gaatattcca tttaccatga ggagtcatat
     6721 atttaagtgt aacttcatct tttactggcg gaacatcaac atctcctgga gccattacaa
     6781 ctggtggtaa agatggttta taagttgcca tattttcacc aaattcccgg aaaatttcat
     6841 gatcaaggta gtaatgttga cgtcctgtaa gagtaaatgt aggaacattt cgttcagtca
     6901 ttaatgaaaa tggtgtgtag cgagctccac catgtttagc agaagttccg attggtgttg
     6961 gataggcttc ttgtggttga gcagtgattt gcttaaacga cattgaatca tcagcatgac
     7021 cacgaccaat atctgtcaaa tgttcaccag tccgttcttg cttcttttcc caagctcgat
     7081 cagcgagttt accattggaa gcagttgaca tccgtaagat tgcatcacat actttttcgt
     7141 cttcatcaag taatggacag cctgcaccaa tgccttcact agcaattcca ttcatgtctt
     7201 tgagataatc atattgatca tcaactttat agttataatt atttactata ttagggccaa
     7261 gagtgatgta tttgtcatag atcttagtat aatcacgggt aactaatttt aaagaaggca
     7321 tggttttccc agggattggt tctgtttcac cgttcttcca atctttaatt tccccgtatg
     7381 gttgagcgat ttccccttga gtattatgtc ctagtggtgc gctcttaaga tcatagaaag
     7441 ttcccggcat gtatttcttt gccatttcag aaacagtctt agccaagagc ttgaattgtt
     7501 gccagtcaga ctttgattcc cacattggac taactgctgc attaaatggg tgaataaatg
     7561 gatgcatatc agttgatgaa aggtccttct tttcatacca agtagcagct ggtaggacaa
     7621 catcggagta cattggtgtt gaaaccattc ggaagtccat atcaacaaca agatctaact
     7681 taccaattgc tcccttgtca cgccaaatca tatcctgagg cttaacccga tcattgggtt
     7741 tagcaagtaa tccattttca gcgcctaata aatgtttcat aaagtattcg gcacctttgc
     7801 cagaagaagc aaataagttt gaacgccata agaagaacgc tttgggttga ttttggttag
     7861 catcaggatc ttcagcagca aaatgtaaag agcccttctt caattcatcg acaactttct
     7921 ttgaaatttc attaatatca gttgtattgt aatcttttgc aaaagataac ggattacgat
     7981 caaattgtgg atatgatggt aaccatccta aacgaattgc catttgatta taatcagcat
     8041 tatgtaagta ggaatgttta ctcttccaaa caggtgattt ttgagcttgg ttatcaattt
     8101 cttcataacg ccattgatca gttgcaaagt aataccaagt agtaccttgc atttgacggg
     8161 caccaccttt ttcccagtca ttagcaaaag taatatttgc ccaaccttct tgtggacgga
     8221 gcttttcttg accaacgtag tgagcccaac caccaccagt cataccaaca caaccacaca
     8281 acatcagcat attaataatg tttcgatagt tcatatcggc attgaaccag tggttgaccc
     8341 caccacccat gattaccata ctccgacctt cgttttcggc cgcgttttgg gcaaattcac
     8401 gagcaatttg aataacttgc tctgctttta ctcccgaacg gctttcctgc caagcaggag
     8461 taaagtagct cttagcatcc attgcatctt tagcagcaag ttcatcatta ccagtccgat
     8521 taattcccat ttgagccatc atcagatcat aaacattagt taccaagtgt tctttgccat
     8581 ctgtgaattt gagcttttta actggtaaat gacgttgcac aacgctgttt ccgtcattac
     8641 taaatgctgg aaaatcagca acaatttgtt cagtttcgcc atcttgatca ttaatagaga
     8701 gtgccggatc aatcttatta ccattttggt ctaataattc aagattccat ttttccttag
     8761 cattatattc ttgtcccatc gttccatttg gaacaacaat cttgtggttg ttttggtcat
     8821 aaacaactgt cttccatgct ggattgacta tcgtatcatc atcaactaag tcactaatcc
     8881 ggacgaagcg acctggtgta tagtgatcac catttgctgt acttggttcc aattcaacca
     8941 tgaatggtaa atcagtaaat cgcttggaat aatcaatgaa acgtttaact gggtgctttt
     9001 ggtagaattc atctaaaatt acataggtca tggcttgagc aacagcagaa tcactacctg
     9061 gttctggtgc aagccagtca tcagcaaatt tcacattttc agcataatca gggctaactg
     9121 ccacaatctt tgttcctttg tacctaactt ctgtcatgaa gtgtgcatcc ggcgtccgtg
     9181 ttaatgggac gtttgatccc cacataataa tgtaggaact gttataccat tctgcagatt
     9241 ctggaacatc agtttgttca ccccaaactt ggggagatgc aggtggtaga tcagcatacc
     9301 aatcatagaa actcatttgt tccccaccca ttaaggcaat gaaccgtgct ccggcactaa
     9361 aactcatcat tgacattgca ggaattgggg taaaaccacc aatgcggtca ggcccatact
     9421 tcttaattgt gtataagcaa gcagctgaaa tcatttctaa tgcttcataa cgatgaacac
     9481 gaattaagcc accgtgtcct cggaccttct tatatttttt agacttttct ggatcttcga
     9541 caatacttgc ccacgcatct aagggatttt catgttcttc cttggcagca gtccaaagct
     9601 cccataattt gccacgaata tatggatact taattcgaac gggactgtat tcataccaag
     9661 agaaactagc tccccgagga catccccgtg gttcatatcc tggaatatta gggccgcatg
     9721 atggataatc tgtggcttgg tgttcccaag taataattcc ttgcttgacg taaacattcc
     9781 aagaacatga gcctgtacag ttaactccat gagttgttcg gacaactttg tcatgcgccc
     9841 atcgctggcg ataaagcttt tcccaacgac gactattttc ttcaagttgt gtaaaggttc
     9901 cattaaactt atcaaccttg ttaaagaacc gtgacttcat cgttgattga cctcctttat
     9961 tgaatggctt accaatatta aaaataaagt aagtcttttc cctaatgtaa agattagcac
    10021 cataactgct atactacgac tagggaaata cctatatttt gaactaaatg aggtgctaat
    10081 atccatgaat cgttacgatc gtcaagaaag ggtacatcaa attggtagta ttggtcagca
    10141 aaaaattagc catgcaacta ttatgattgt cggtgtaggg gcattgggaa gttatacagc
    10201 cgagcaactt gtccgtgctg gagttaaaag acttgtcttg attgatcctg acactgttga
    10261 cgtaactaat cttcaacgtc aatcactttt caccgaagaa gatgctagca aacaacggct
    10321 taaggtcgaa gcagctaaag aacatttaca taaaattaat tcagcatgtc aaattactgc
    10381 gatcccagcg ccgattactg ctgaccttat tgacgaatat cagtttaccc tttgtttaga
    10441 ctgtcttgat aattatcaag cacgggatct attaaacaaa ttagcaatca tcaaaaactt
    10501 tgattatctg tttgccagct gtgcaggaac ctatgggaac gtaatggcga tttcgccaca
    10561 aaatcatccc tgcttgaact gtctttttcc taatattaat gaattaaaac aaaacgattg
    10621 tgatttaatt ggggttaata ctgctttaat tccgattgta gcgggactac aggtatcttt
    10681 agcgcttcat tatctggttg acaaaacaca ggttaatttt aatgaattga tcacggttga
    10741 caattggtca atgcaattta gtaagtttgc tattaataaa aatcaccatt gtcccgcctg
    10801 tgctaagcct agcagtattt ctttagaaga agaatcagga ccagaattac atatgttatg
    10861 tggggaaaat gcatattata cagtcaaaga gaaacctatt aattttggca gacttaaaga
    10921 atttttggct aaaaaagagc tcttaattaa cgcaaatcga ttatttcttc attttaaatg
    10981 ggaaaatcgt ccagtaagta tattcaagaa tggtaagatt gttatgtatg acttacctac
    11041 ttcggcgatt gcccagaaac agtttaagtc gttaaatatt ttgatgaaag aagacctatt
    11101 atgaaaaaaa tcgcaatttt aacggttagc gatagccgaa cattagatag cgatacttct
    11161 ggaaaattaa ttgctatgaa gatggctaac gcgggcttat cagtagttga tcgggtaatc
    11221 gttaatgatg atattgtcaa tattcaaact gcctaccttc aactagaaca acaagctctt
    11281 gatatcatca ttactaatgg tggaacagga attgctcagc gtgatgttac tattccggct
    11341 attcgtccac tcctcaaacg cctaattccg ggttttgggg aagcgtttcg ccagatatcc
    11401 tttgaggaaa ttggtactcg tgcgcttgca tcacaagccc tagccggatt taatttccgc
    11461 aatcagctta cctattgttt acctggttcc cagaatgcct gtcaaacggc tataaacaaa
    11521 ctaattttgc cagaatatga acatttatta tttgaaagca gttctcaacg aaaggaagtt
    11581 catcaccatg ctcactagaa gaattccaat ctctgttgcc gaggcacaga aaaagattaa
    11641 cgaaatttcc cttaaaacag ctacagagac aatcccgtta tcagaagcta accaccgtgt
    11701 tttagctaaa gatgttcatg cccattatga ttatcctcat tttcgacggg ctggaatgga
    11761 tggttatgcc attttagcca gcgatgatca tgatttccct cgcgaattta acgtccgagg
    11821 agagattcaa gctggagcaa cttgggatca accattacaa tcaggggatg cggtccgaat
    11881 tatgactggt gcatatgtcc cttctgatgt aggaaaagta attcgaattg aaaaaacgcg
    11941 gcctgctaaa gatgaaaata aggttcaaat tattacgact gaaagcaaga ctaacattac
    12001 ggaagctggt actgatgtaa caagactaac attacggaag ctggtactga tgtaaaaagc
    12061 ggtgatatcg ttttagcaaa agaccaggaa ataaatcccg gtggcctagc agttttaacg
    12121 gcttttggtg ttcaagaagt aacagtttat aaaaaaccac ggattgcaat tatcgccact
    12181 ggaactgaat tattaggacc taatgccacg attgaaccgg gaaagatctt taatagtaat
    12241 ggtattatgt taaaaaatct tgtagaagaa actggtggga ttgttgattt tgaaacccaa
    12301 ttaccagatg atgctgatct tatcaagcag actcttgaag aacaaatagc aacgcatgaa
    12361 attgtaatta ctgatggtgg tgtttcagtt ggtgattttg attttattgg agatgaagca
    12421 cgtaaagctg atgaattgct ttttaataag attaaacaac gaccaggaag cgttacgact
    12481 gcctttgttc aaaatagtac gttaataatg gccctttctg ggaatccagg agcttgtttt
    12541 actggttttt acctttatat ggaaccgctg attcgccgtt atcaacacca agtcagccga
    12601 attaagcaag tacgggcaat attaacggcc ccatataata aaacaaatgg gtttgatcgg
    12661 tatcttcgtt gtacttataa attcaaagat aatcaatttt atgtttatcc aaatggaatc
    12721 aacagatctg gctcattagc taacctccag acgacaacct gtttagcact gattccgcat
    12781 agtactactc caatgaaggt cggaacggag acagacgcat ggctattacc cttcaaataa
    12841 tcggtcataa aaaaagcggc aagactctta tcactacgac tttaatcgaa aggctctcaa
    12901 aagaagggta tcgagtagct gctcttaaac atgatgccca taatgccgca atggatgtgc
    12961 caactactga tagtgctaga atgagtagtg ctggagctaa acaggttatt ttacaatctg
    13021 cgactgaatt tttctttcat caaaaaagta atgtgccgtc tttaacggaa atggttgaat
    13081 tattaagtac cgacaatgat tttatcttga ttgaaggcca taaggaagcc actcaatatc
    13141 cgcaaatttt attattaaag cctggcgaag attctaccaa tgttgctcat actccccctc
    13201 ttaaaacagg tagtatcttt aatggaacaa ccgctgactt attaggaaaa gatgcaattg
    13261 taaattggtg ctatgactac ttaaaacaag taaaggggga tgcagaatga ttggattagt
    13321 atatgctggt ggtaaatcta cccgttttgg gaaagataaa gctacttatc atgttccagg
    13381 attaccagct accaatatag agctagctgt cgagaaatta acaccccttt gtcagcagat
    13441 cgttgtttgt gctaatgaaa taaatcgagc gcatatatta aagttggttg gtcaagaacc
    13501 ggctgtgcag attatctgtg atattccccc ttatgatcat catggtcccc tctcagcaat
    13561 tattgcttgt actaaccaat tttccattgt tcaggattat ttaaccttgg ctgttgatta
    13621 tccatatatc accaaaaatt cacttgccgt tcttgcccgt acacctaatt cttatattgc
    13681 aacaagtcag cacaatcact attcattagc tcatttttca gttagcaatg aacaagttac
    13741 tacttgggtt gataataatg atgactggcg attacgtagt ttcatcacta ataagtgcgt
    13801 ctgccacccc cttacgtatc gctcaagtaa cgaattttca aatttaaact atcgtgaggt
    13861 cgatttaaat gaaaagtaaa gattcaatga caaatcctga ttttcagaag ctcatttccc
    13921 ttgttttaaa tgacttaaca attagacgaa caatgctaga aaatcgggaa caagaagtga
    13981 gccaacaaat gagttcgctg gaaaaagatg cggagttaga acaattggac gaccaaattc
    14041 aacagattca agctgatttt gatcattacc gcgaatttca ggatccggaa tttgatttta
    14101 gtgcaactaa gtatttccag ggaccatcga tgggattacc acgacatcct taaaactcag
    14161 acggcagggc taaagaagca gagcttttct tagccctgcc ttttaagtgg gccagcgttg
    14221 cttctaactc gagaaagcgt tattatataa aataggaata ttgtaaggac aattggggaa
    14281 ttttattggg gaggaagcag atcgtgcttg aaacagctaa ttggatacaa aaatatttta
    14341 atcaatcacc agatgcaatc ttcttattta aaaatgatga tcttttagtc agtaatgagc
    14401 cggcacaacg gttagttact atgcttaatt tagatgtcaa ttacctatta caaattggaa
    14461 agaacgcttg gtcacaactg gaaaatgatg actgtgcgtc atgtctgatt aaaaagcggt
    14521 taaaggaagc tgcagttccg ataacatttc attccaatgc tactcatccc tttcactttt
    14581 cgatggttta ccgtcctctt gatgataaag aaaatgtctt tgccctaact cttgaaaatc
    14641 gtgagcaaca gcagcgtctt tctcaggttg aagagcaccg aattcttaat caatacgtaa
    14701 atgaagcgca cgaaaaagaa cggcaaaaaa tttcacaaga tcttcacgat agtgttgcac
    14761 agggaatcta tgcagcaata atgggcattc aaagattagc aacggtgcaa aatcaaagaa
    14821 atactgagca atttcaatca atgagtgctg caatcgaaaa gcagttacaa acgaccctta
    14881 aagagattaa agggctcgca cttgatattc gcccctcagt tcttgacaat tttggcttaa
    14941 ttccggcaat caaagctttg gcgaaacgtc ttcaaaatag tacaggaatc acaattgatg
    15001 ttatagccct tacctctgct gaaaaattac aaaaaaacat tcaaaacgtt ctttaccgca
    15061 ttacacaaga ggcaattaat aacgcaatta aacatgctca ttcaacagaa ataagtatta
    15121 ttgttacgga tcacagcagt taccttcagt tagagattct tgataatgga attggatttg
    15181 atattgatca gcatagtgga tttaatgggc attcacttgg attaatgaat atgaatcgag
    15241 taggagataa ttgattagtt caattatcga cctctcacac caccgtacgt acggttccgt
    15301 atacggcggt tcgacaactt aatcacattg aattgac
//
