LOCUS       c00041_JAJGTL0..       12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGTL010000098.1 Limosilactobacillus reuteri strain R.n.3-A
            scaffold98, whole genome shotgun sequence.
ACCESSION   JAJGTL010000098
VERSION     JAJGTL010000098
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 11:01:55
            Original ID  :: JAJGTL010000098.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 109214
            Orig. end    :: 121365
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[114214:116365](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7151
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             441..1835
                     /locus_tag="ctg41_110"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLCLLVLVVGCMTIHQRRHFNKNVKIDNVSVGG
                     LTAKQALKKLQDNPQSPKIYVNNELVFTDKQSVAKFSSADEQKIKNALHSQYTFFPSSK
                     AKNIAIKPQNVNQDEVSKIDQAVSQKVTELNNGRKAPVDAYAVYENGRVQVKPAVGGTQ
                     YSLDGLHNKVENEIAGGTIHLKPEYTTPLSANSKTVQNEKAKLEELSKRSVTYQVQNKK
                     YQLNCGEIITRATYQNGKYHFDTGAANSKIDEINNTQATLGKSFEFKTHDGSVIKTTDA
                     GSYGWKISKKQAGKTLTNALIENKQTVNAKNDIYGKGYNQQGTGYNTTSNNGIGDTYAE
                     VSLADQHAWFYKNGKCVLSTDIVSGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVQYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFSDLHKN
                     EPVVIY"
     CDS             1959..2123
                     /locus_tag="ctg41_111"
                     /transl_table=11
                     /translation="MVDLDLETKKNLVIINLFYIGLIALYCILHAGPLNFLVFLGMLVL
                     ANIAEFVVK"
     CDS             2150..2281
                     /locus_tag="ctg41_112"
                     /transl_table=11
                     /translation="MLKKSYKFLSRKELSKVLGGWGYSLAFKSPRSWERAVLNWIKR"
     CDS             2778..3590
                     /locus_tag="ctg41_113"
                     /transl_table=11
                     /translation="MLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCATGFINFVKSS
                     QQTQRQQQIIDKYQAQIASANQLNQQYNEIRRERHDTRNMLLSVQGYIRDHKDKEAEKL
                     LATFLQNDTLEKHYDEIDNALDKIKISGLHNLIKEKAYKIVEKGIPFSFEVNAEIDELP
                     GSEIKTARIIGILMDNAIEATFKQAKPYIQFALLKHSPEVYELVIANSIEQKLNINTAL
                     KFEHSTKEGHQGIGLSNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             3598..4371
                     /locus_tag="ctg41_114"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEVYLAILDIELENQLSGIDVAEQIRKKAEFAEIIFITAYQEYLPYTVSHR
                     IEPFDYISKGEQIESIADRLRTDIDEAYARYQNYMNSNQKHQEKFTYEPTHGVKRQVDF
                     ENLYYIESVKNTNRRLRIVGKDIRIEYRGELGQVNNKHLLKVNQSTLINPKAIREFNRK
                     ERVVYFDENQEIKITVSYRKIKSLVNFLEKDNNGL"
     CDS             4566..4724
                     /locus_tag="ctg41_115"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVRDIVNSLNKWAQSCYAG
                     YHDSPFH"
     CDS             4737..4922
                     /locus_tag="ctg41_116"
                     /transl_table=11
                     /translation="MVKVRINKQFYKDFNFYFYMLFIVLWIKPLIDVENGYEFTYCLVF
                     LVGAIIATLLTIFKNK"
     CDS             5001..7151
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 321.7; E-value:
                     1.6e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_117"
                     /sec_met_domain="TIGR01193 (E-value: 4.9e-275, bitscore:
                     907.7, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.8e-39, bitscore:
                     127.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYLHYVAQVDEADCGVASLAMILRNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFDRLWSGVCLLFSPAKGYTPQKEPLAGLTTMFQQLTNY
                     KKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLTILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAILVIQDRLSIGTLMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDTEKSDTNSQDQTDLIGPINIQHVDYSYEYSHPILQDINLQIGCNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQLPQLFSGTIKDNL
                     LMGLDREVSAEEIDNACKLALIYNDIQEMPLNYETKLDEEATALSGGQKQRLTIARALL
                     TSARVLIFDESTSSLDPITEKRIVENLLEIEDCTMIFIAHRLSIAKKVNKVVVMRDGKI
                     IEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7081..7317)
                     /locus_tag="ctg41_118"
                     /transl_table=11
                     /translation="MKIHFNKDFWRNGFFYIYLLLLFLWIAPFSDGSVPCLQLCLIKTE
                     KRLQQQCSEPFMHSTNYSILDDDSKVPGEYPVQ"
     CDS             complement(7596..8024)
                     /locus_tag="ctg41_119"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             complement(8093..9088)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 298.7; E-value: 5.8e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_120"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTADV
                     DGLVIQQRSKVPADIYEKLHTNGLKQIATRTAGFDMVDIKKANENDLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSTEIHTATIGIIGVGRIGGTLAKL
                     LHALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPTSKGLLTANDFEM
                     MKPTAGLVNASRGPVVNTADLVTALKKGTIAAAALDTFEGEETVAATNRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMAILNGEKSPHEITL"
     CDS             complement(9090..10277)
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     1.7e-72. Score: 236.3. Matches aSDomain:
                     nrpspksdomains_ctg41_121_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 269.9; E-value: 6e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_121"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5.6e-07,
                     bitscore: 22.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFAKLTPGGIREFDYQVSAIPGIIKLTLGEP
                     DFNVPTAMKQAAIDSINANDSHYAPGNGTLALRQAIAHFMQDRYQLDYNPENEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSSDDFILTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTVKSTNLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGFELINPQGAFYVFAKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIASFINKEN"
     aSDomain        complement(9117..10169)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg41_121_Aminotran_1_2.1"
                     /evalue="1.70E-72"
                     /label="ctg41_121_Aminotran_1_2.1"
                     /locus_tag="ctg41_121"
                     /protein_end="387"
                     /protein_start="36"
                     /score="236.3"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPTAMKQAAIDSINANDSHYAPGNGTLALRQAI
                     AHFMQDRYQLDYNPENEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSSDDFILTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTV
                     KSTNLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGF
                     ELINPQGAFYVFAKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             10782..11003
                     /locus_tag="ctg41_122"
                     /transl_table=11
                     /translation="MRIDIKHYLEVNHLTIYQVSKRSGYGYTTLHKSFNKPQSSSTSLN
                     LRDLDALAHAQGKSMWEVLKELEEHYLE"
ORIGIN
        1 gtgtcgccaa cgcaaacaac cggcggacag gaagccgaaa gacaactcaa gctgcatcaa
       61 ctcaacaacc tgtaacagtg gaagacggga tgaactttag ctaccgggct gcgcaaaaag
      121 cgggcgtgat tgataacaat acatctgttg aagagtttta caaaaatgcc aaggaaggta
      181 atggttctgt aacctacaac ggtcaaacta tttactacaa agctaagggt aataatcaat
      241 atcaagttac aaccgctaaa tagtttggtt actaaaaagt gtccggtatt tttgccagac
      301 gcttttttag taaaaacact atgaaaaatg taaaatatac taattgttta cgctttagta
      361 tataatgaat gagcgtaatg aatatgttta tttagtatag aaattagact taaagatttg
      421 gatgttatgg gagtactttt atgcaaaaac tatctattaa acaactaata ataattacat
      481 tgtgcttatt agtgctggtg gttggctgca tgactattca ccagcgtcgt cattttaata
      541 agaacgttaa gattgataat gtgtcggttg gtggattgac tgctaaacaa gcattaaaga
      601 agttacaaga taatccacaa tcgccaaaaa tttatgttaa caatgagtta gtatttacgg
      661 ataagcaatc agtagcaaag tttagtagtg ctgacgaaca aaaaattaaa aatgcattac
      721 atagtcagta tactttcttc ccatcatcta aggcaaagaa cattgcgatt aagcctcaaa
      781 atgttaatca agatgaagta tcaaagattg atcaagcagt cagtcaaaag gtaacagaat
      841 taaataatgg tcgaaaagct cctgttgatg cttacgctgt atacgaaaat ggccgagtac
      901 aagtaaaacc agcagttggt ggtactcaat acagtttaga tggtttgcat aataaagttg
      961 agaatgagat tgctggtgga acaattcatc tgaagccaga atatacgact ccgctttctg
     1021 caaatagtaa aactgttcag aatgaaaaag caaagctcga agaattatca aaacgatctg
     1081 taacatacca agtacaaaac aaaaagtatc aattaaattg tggtgagatt attaccagag
     1141 caacatatca aaatggaaaa tatcactttg acactggagc agctaattca aagattgatg
     1201 aaattaataa tacccaagca actcttggca aatcatttga attcaaaaca catgatggat
     1261 cagtgatcaa aacaacagat gctggttcat atggttggaa gatcagtaag aaacaagctg
     1321 gaaagactct tacgaatgca ttgattgaaa ataagcaaac agtaaatgca aaaaatgata
     1381 tttatggtaa gggttataat caacaaggaa ctgggtataa taccacaagt aacaacggca
     1441 taggggacac ttacgccgaa gtttcattag ccgaccaaca tgcgtggttc tataagaatg
     1501 gtaaatgtgt tcttagcact gacattgtta gtgggaccaa taacaaagat aacgagacgc
     1561 cgaagggtgt ctggtatatc atgtaccagc aaacaccgtc tgttcttcgg ggccttaacg
     1621 atgacggttc gaaatacgct agcaaagttc aatattggtc accatttact gatagtggat
     1681 gtggatttca tgatgcaagt tggcgtcacg attggtcaaa acaggcttat cttgctaaag
     1741 gcggtggatc gcacggttgt attaacatgc atccagatgt agctggtcaa gcttttagtg
     1801 acttacataa aaatgagcct gtggttatct actaaaggag gagatgttgt gcgcccgagt
     1861 gctgaacgcg caattatgat tgcaatagct tgctttgttt taacaattat tatttctttt
     1921 gcattatcag agggatggat aaagtaggag ttagttatat ggtggatttg gatttagaaa
     1981 cgaagaaaaa tttggtaatc attaaccttt tttatatcgg attgattgcc ttgtattgta
     2041 ttttgcatgc agggccactg aattttttag tgtttttggg aatgttagtt ttggctaata
     2101 ttgctgaatt tgtagttaaa taggtaattg ttatttattg gaggtaatta tgttaaaaaa
     2161 atcatataaa tttttatcaa ggaaagaatt atctaaagta ttaggtggtt ggggatattc
     2221 acttgccttt aaaagtcctc gttcatggga aagagcagtt ttaaattgga ttaaaagatg
     2281 attcatttaa ctgtaggaca aggattaacg tcatctatat taaatattat tgaaataata
     2341 ttaatatatc aattggtaac tagcgacttt tcattaggat tagtaataat tgatttttta
     2401 gcagtcttga tgattatatt tttttcaata gtatttttta tgttaggatc gctataccca
     2461 gtacttatag tattttattt ttggttagtt gacagaataa aatctaattc ttatatagtt
     2521 ataaatagta ttcttgcgat gtgtattagt attgtaatgg catctttatt cgatttagta
     2581 gatcactata cttatacgtt tttttacaag gaaagacaga tatagcactt ttaggatggc
     2641 ttattccaat taatgattta atcataacta ttgtagttgc aatcttagca gttaaagtag
     2701 ttcgtcccaa actgagatgg attaggatta attttcctcg accgataggg ttatggcaaa
     2761 ttacggcaat tttgttcatg ctttatgtgt ggttaactgc tattgccgaa aaggacgggg
     2821 tagcaaataa gtatgcctcg ctgttgttaa taatgtattt gataattatc gtagtgtgtg
     2881 caaccggatt tattaatttc gttaaaagta gtcagcaaac acaacgacag caacaaatca
     2941 tcgataaata tcaagcgcaa attgccagtg ccaatcagct gaaccaacaa tacaatgaaa
     3001 ttcggcgtga acgtcacgat acacgcaata tgcttctcag tgttcaagga tatattcgtg
     3061 atcacaaaga taaggaagca gaaaaattgc tagcaacgtt tcttcaaaat gatacacttg
     3121 aaaagcatta tgatgaaatt gataatgctt tagataagat taaaatttca gggttgcata
     3181 atcttattaa ggaaaaggct tataaaatag tcgaaaaagg tattccattt tcgtttgaag
     3241 ttaatgctga gattgacgag ttaccgggtt cagaaataaa aactgctaga attattggaa
     3301 ttttaatgga caatgcaatt gaagcaacct tcaaacaagc caaaccatat attcagtttg
     3361 cattgcttaa gcacagtcca gaagtttatg aattggtaat tgctaattcg attgaacaaa
     3421 aacttaatat taatactgca ctgaaatttg agcattcgac caaggaagga catcaaggga
     3481 ttgggctttc aaatgtgacc cagttagtag aaaatgatga ccattattct ttttcagcgg
     3541 aagttaaaga taaggtaatt atgatgactt gttttattca gggaaagtga gaataaaatg
     3601 ttaaaagtaa ttattttgga aaatgatgat tatcaagctg attatactga gcgtctagtt
     3661 tctcagcgaa aattgattaa cgctactcca aatagttatg acatagaatt atatttgcgg
     3721 acaaatgatc cgcaagaagt gattgatagc atcaaagatg aggtttattt agcgatttta
     3781 gacattgagc tagagaatca acttagtggg atcgatgttg ctgagcagat ccgcaaaaaa
     3841 gctgaatttg cggaaattat ctttataact gcatatcaag aatacttacc ttatactgtt
     3901 tcgcaccgga ttgaaccatt cgactatata tcaaagggag agcagattga gtcgattgcg
     3961 gatcggctcc gaacagatat tgatgaagca tatgctcgct atcagaatta catgaacagt
     4021 aatcaaaaac atcaagaaaa gtttacttat gaaccgactc atggagtaaa aaggcaagtt
     4081 gattttgaaa acctctatta tattgaatca gtaaaaaaca caaatcgccg gttacggatt
     4141 gtgggaaaag atattcggat tgaatatcgt ggcgagttag gtcaagttaa taacaagcat
     4201 ttgttgaaag taaatcaaag tacgctgatt aatcctaaag caatccgaga atttaatcgt
     4261 aaagaacgtg tggtttactt tgatgaaaat caggaaatta agataactgt tagttaccga
     4321 aaaataaaat cattagttaa ttttcttgaa aaggataata acggtttata aagttcaaaa
     4381 gaaactgtga caaaaaaagc tgtcatagtt tctttttatt atcaagcgat tttagtaaac
     4441 gttttcgctt ttttactacg aattctgcag aaaggtttac gaattttgca aaatgacaca
     4501 gaaaaaattt ttacttatat actaatgttg gaatcctaac tttatcgtat caggaggtaa
     4561 ttaaaatgac ttatcgtaaa ttaaactttg atgaattaag caaggtttct ggaggatgga
     4621 gtctctcttc acaggttaat gaactagtta gagatattgt taattccctg aacaaatggg
     4681 ctcaatcgtg ttacgcaggc tatcatgata gtccattcca ctaataagag gagaagatgg
     4741 taaaagtgag aattaataaa caattttaca aagattttaa tttttatttt tacatgttat
     4801 ttattgttct ttggattaaa ccgttaatag atgtagaaaa tggttatgaa tttacttact
     4861 gcttagtttt cttagttgga gcaataattg ctactttatt aaccatattt aaaaataaat
     4921 agtattttat aagaatataa agcccagaat cattattaat tttggacttt atttctttgt
     4981 ctgattagaa agtaaggtga atgaaaatca attatcttca ttatgtagcc caagttgatg
     5041 aagcagattg tggggttgcc tccttagcga tgattttgcg caattttggc tctgtttatc
     5101 caatcgcaaa attacgtgac ctagcccgga cgactaagca aggaactacc gccttaggac
     5161 ttgtaaaagc agcaaagcat cttggattag acgttatacc cattcaagca gatatatcat
     5221 tgtttgatga tcctgaaatt acttacccat tgatcgcgca tgtgattaag gatgatttac
     5281 ttcattactg tgttgtcttt aaggctgatc aagattacat ctatgtagct gatccagatc
     5341 ctgctacgaa agtacaaaaa atgacgcggg atgaatttga tcgtttatgg tcaggcgtat
     5401 gtttgctttt ttcgcctgct aaggggtata caccgcaaaa agaaccttta gctggattaa
     5461 cgacgatgtt tcaacaatta actaattata aaaaagatat atccggaatt gttattgcgg
     5521 caatgctaat tactttcatc agcatcgtcg gttcatacta tctccaatta attattgatc
     5581 ggtttattcc ctcgaaaaat attaatggct taacgatcct tgctggtagt ttattagtag
     5641 tgtatgtgtt taattctctt tttaattatc tgcgggatgt tcttttgact aggctggatc
     5701 aaaaactgac atcacaaata agtcttagat atattcacca tgtttatcgt ctaccgatgc
     5761 gatttttctc cacaagaaaa acgggagaaa ttacttcacg gtttaatgac attaataaga
     5821 ttattgatgc cttatcaagc actattattt caatgttctt agacgttggc gtgatggtga
     5881 ttataggaat tgttctttct ttatatgatc ggtcattatt tttaactaca attagtacca
     5941 ttccgattta tgtcattatc atttatgcct ttaataagcg ctttgctaaa cttgatcagg
     6001 aacagatgga gagtaatgct caattaagtt ctgcaattat tgaggattta aaaggcgtag
     6061 agacgttgaa agtgctgcaa cttgaaaata tccgttataa aaatgttgaa aagcaatttg
     6121 cggatttttt acgaaagaat ctaacatatg ttaaaactaa atcttttcag gatgcaatta
     6181 aaatgtggat tcaatacggt ttagtaacaa tcattctttt tcaaggagca attttggtaa
     6241 ttcaagaccg attaagtatt gggacattga tggcctttaa tgcattatta gccttttttg
     6301 tcagtccgtt gcaaaatatt attaatcttc aacctaaact ccaagaagct aaagtagcga
     6361 ataatcgatt gaatgaagtt ctgcaagttg ataccgaaaa gtcagatacg aattctcagg
     6421 atcaaacaga tttaataggg ccgataaaca ttcaacatgt tgactattca tatgaatata
     6481 gtcatccaat tttacaagat atcaatcttc aaattggttg taatgataaa ttggcaattg
     6541 tagggttgag cggttctggt aaatcgacct tggcaaagtt gttagttggc ttttatttac
     6601 ctactcaagg gcagatagaa tttaatcagc ataagacaac agagattaat ctttgcgata
     6661 ttagacaata tgtgcattac ttaccccaat tgccacaatt attttcggga acaatcaaag
     6721 ataacttgct aatgggatta gaccgtgaag tatctgctga agaaatcgat aatgcatgta
     6781 aattggcatt aatctataat gatattcaag agatgccctt aaactatgaa acaaaactag
     6841 atgaagaagc aactgcatta tctggtggtc aaaaacaacg cttgacgatt gcacgagcac
     6901 tcctaacttc tgcgcgtgtt ttaatttttg atgaatcaac aagtagctta gatccaatta
     6961 ctgaaaaaag aatcgttgag aatttgcttg aaattgaaga ctgcacaatg atttttattg
     7021 cccaccgtct ttcgattgct aagaaagtca ataaagtggt agtaatgcgc gacggaaaaa
     7081 tcattgaaca gggtactcac caggaacttt tgaatcatca tcaagaatac tataatttgt
     7141 ggaatgcata aaaggctccg aacattgctg ttggagcctt ttttcagtct ttattaaaca
     7201 taattgcaag catggaaccg aaccatctga aaatggagca atccagagaa acaaaagtaa
     7261 taagtatata taaaagaaac cattccgcca aaagtcctta ttgaaatgaa ttttcattag
     7321 ttctccccct aagacagtat gtgtacctta ttataatgaa agatctaatt taaaggacat
     7381 tttgcaaaat tcgttaagtt tcttgcagaa ttcgtatagg ttgcctattt agaaagggac
     7441 tgtgacataa gcgaagttac tttcataaaa aaacaaatgg cgcagtacac caatggcctc
     7501 caacgctcgg taaaaccgaa tgttggaggc ctattgttgc ttgcgggggc tcgaaaacga
     7561 agtcacgagt gacttctgtc tcgctccctt ttcaactaat caacttttac aaatccatct
     7621 tgaacaaatt tcgttccgta ggtcagagtg ttttccacgg gacactttgc ggcaacgtca
     7681 gcgagaaact tcttgatgtc ttcatcagac tcgctgctgc gaagatgtgg ttggtaacgg
     7741 atctcagtaa acttacgaac attcttgcca tcagcaacgt cttcacgacc aagatcaccc
     7801 tcgattgtta cccaaaaagc tcgtaaatca aagttacgct ttttagctaa tgcttgggca
     7861 gtgattgcct gacaggcacc aaatgatgca aggagaattt ctactggatt catccccgta
     7921 tttgtacttt ctggttcatc aaatgtaatt tcaaaaccac gggtaccggc tgaaacttgc
     7981 atccccgttg ttgttttagt tgctgttact ttatatttac tcatagccgt tccctccttt
     8041 taatacccat agtgtaatcg agacgatact tttggtcaat gagggtgctc aattataagg
     8101 taatttcatg tggtgatttt tcgccattaa ggattgccat cacatcatca agtgaaatat
     8161 ccaccatgtt tttgactgct aaattagtaa agaaggcaat gtggggagta agaatgacat
     8221 tatccatttc gtgtaattct ttaacaagcg gctgatcgtc aagtcctttt tctcggcgat
     8281 ttgtggccgc caccgtttct tcaccttcaa aagtgtcaag agctgctgct gcaattgttc
     8341 cttttttaag ggctgtaact aaatcagctg tattaacgac tggaccacgg ctagcattga
     8401 ccaagccggc agttggtttc atcatttcaa agtcgttagc agtcaataaa cctttagaag
     8461 ttggatttaa atcgacgtgg agactaacaa catcggcttg ttttagtaat tcttctttag
     8521 aaacgaactg gacaattcca tcgaggtcag tgcgcggatt cgtatcatat cctagaacgg
     8581 tagcacctaa tgcatgaaga agttttgcca gggttccgcc aatgcgtcca acaccaataa
     8641 tcccaattgt ggcagtatga atttccgttg attgttcgtc gctaaaccag cggaagtcat
     8701 tttcggcgac ttggtggtca aagcggtaag ttttccgaag caaccggaaa atctgcatta
     8761 atgcaaactc ggcgacactc cgcggcgaat atgctggtac attggtcacg actaagtcat
     8821 tttcgttagc ctttttgatg tcgaccatgt caaatccagc tgtccgtgtc gcaatttgtt
     8881 tgagcccatt ggtatggagc ttttcataaa tatcggctgg aactttactg cgttgctgaa
     8941 ttacgagtcc atcaacatcg gcagttaatt caacagcatc gtcaatcaat ttcggcgttg
     9001 tgatgatttc gatattgtgt tcttttgcgt attcgttaat ggcggtttgt tcatcgtccc
     9061 gcacactagt catcaagatt tttgtcatgt taattctcct tattaatgaa ggatgcaatg
     9121 ttatcaagag ctccggttaa attttccata ctggtggcgt aactaattcg aacatatcct
     9181 tggcccccag ctccaaagaa ggaaccagga atcacagcaa cttttccttc attagcaaga
     9241 tccgtcgcaa atttaaggtc atcattacca tattgttcag gaatcttggc aaaaacgtag
     9301 aaggctcctt gaggattaat cagctcgaac cctaattttt ggaggttatt aacaacaaag
     9361 tctcgtcgtt gctcataggc atctttcatt tcttgagtag ctgtttttcc ttcgtcagta
     9421 ccaaatgcag ctactgcagc ggccattgct ggattagaag cagcagttac taacattgcg
     9481 tgaatagcac tgactgattt catcaattct tgcggcccag cgataaaacc aatgcggtaa
     9541 ccagtcattg catgtgattt tgaggcacca tttaaaatta gcgtttgttc ggggatgtaa
     9601 ttagcgattg aagtatgagt agctccgtaa acaagttcag agtaaatttc atctgcaatt
     9661 acaatcaggt tagttgattt aaccgtatcg gctagtgctt taatttgatc ttgggtgtaa
     9721 gtaacaccag ttgggttgga agggtagtta agaactagtc cttttgcatt aggatgttct
     9781 tctaggacgc tttggagtct tgcgggtgtg agaataaaat catcgctgct tgtatcaact
     9841 tcaatcggaa tcccaccaag aatctttgtg acagccatgt agaaggggaa agttggggtt
     9901 ggaatgataa tttcgtcgcc aggattaata atagtagaaa gagaagcgaa aattccttct
     9961 gttgcgccaa ctgtaacagc aatttcgttt tccggattgt agtccagctg gtaacgatct
    10021 tgcatgaaat gagcgatggc ttggcgtagt gctaaggtcc catttcccgg agcatagtgt
    10081 gaatcattgg cattgatgct atcgattgcg gcctgcttca ttgcggttgg cacattaaag
    10141 tctggttcac ctaatgttag tttaatgatg ccagggattg cgctgacttg gtagtcaaat
    10201 tcgcggatcc cgccaggagt gagtttagcg aaattattgt taagacgatt gagaatttct
    10261 tttttagtag ttggcatgat aaattcctcc tatataatat gtagatttag aaaaaagaag
    10321 ccctgaatgc tataggaaaa acatccaggg cttcttgatc agattggaat gagtataaaa
    10381 gaggctctcg gatgtttggg ggtcatccgg gaacatcaca atgataaaat cactgctggt
    10441 tagcggacgg taatcgcgct aaaccagaag acatacgctt gattcaagtg aattgtcgca
    10501 gtgctcatca ttgtgtcctc cttttgatta actgattatt aataattcta attatttttt
    10561 aatttttgtc aagagttgat tgagaaaaac tattaattac aaaattattt attgatgaca
    10621 aatgtaaata taataaagtg tgaaaatgtt tgtgattatt agttcgcctt taatttaata
    10681 ttaaatttat attctacaat ttttttattt ttttcgtgtc ttttttgttg tcttactcca
    10741 caaatgtgat ataatattaa tcgtaaagga agtgggtagc aatgcggatc gacatcaaac
    10801 attatttgga agttaaccac ttgaccattt atcaagtttc caagcgttcc ggttacggct
    10861 acacgacttt acacaaatcg tttaacaaac cacagtctag ttcgacctcg cttaacctgc
    10921 gtgatcttga tgccttggca catgctcagg gcaagagcat gtgggaggtc cttaaagaac
    10981 tagaagagca ttacctcgaa tgagattgtg gctttgctgt agccacagga agttaaatgc
    11041 gttaactttt aacttctaga atacttagac tacgaaactt agaaaacaaa atattatatt
    11101 taattgagga gggattgcat atggctcaaa acccaatgaa tccatttgac aacgacatga
    11161 atgacatctt taatcaatta atgggtggca tgaatggttt caattctgat aatcggcgtt
    11221 acctaatcaa tggtcgtgaa gtaacaccag aagaatttgc tgaatatcgt agaactggtc
    11281 aattgccagg cggtgcaaat cctcaacaag gtgggcaacc tggccctcaa cctaacgcag
    11341 gtaaggacag tatcttacac aagttaggtc gaaacttaac tcaagaagct cgtgaacatg
    11401 aacttgaccc tgttattggt cggaacaagg aaatccaaga aacagctgaa attttaagcc
    11461 ggcggacaaa gaacaaccct gtattagttg gggacgctgg tgttggtaag actgctgttg
    11521 ttgaaggatt agcacaagca attgtttccg gcgatgtacc agctgctatc aaggacaagg
    11581 aaattatcag tatcgatatt tctggccttg aagcaggtac tcaataccgt ggtagctttg
    11641 aagaaaacat gcaaaagttg gttgatgaag tcaagaaggc tggaaacatc atcctcttct
    11701 tcgatgaaat tcaccaaatt atcggtgccg gttcaactgg tgattctagt ggttctaagg
    11761 gtatgtctga cattattaag ccagcattat ctcgtggtga actaacagtt atcggtgcaa
    11821 ctactcaaga tgaataccgg aacactatta tgaaggatgc tgcattagca cggcggttca
    11881 atgctgttac tgttaatgct ccaagcaagg ctgatactgt agctattctt aaaggtatcc
    11941 gtgacttgta cgaacgtcac cacaatgtaa agttaccaga tgacgttctc caagctgctg
    12001 ttgattactc tgttcaatac atgccacaac gtgcattacc tgacaaggct atcgacttaa
    12061 tcgatatgac tgctgctcac ttagcagcaa agcacccagc acgtgatgct aaggcaattg
    12121 aaaaagatat cgaagcagaa gaaaagaagc a
//
