LOCUS       c00028_JAJGUA0..       12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGUA010000046.1 Limosilactobacillus reuteri strain WF-AA1-A
            scaffold46, whole genome shotgun sequence.
ACCESSION   JAJGUA010000046
VERSION     JAJGUA010000046
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 11:17:30
            Original ID  :: JAJGUA010000046.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 79145
            Orig. end    :: 91296
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[84145:86296](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7151)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1807..2994
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     3.6e-72. Score: 235.2. Matches aSDomain:
                     nrpspksdomains_ctg28_46_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 273.1; E-value:
                     6.2e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_46"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.3e-07,
                     bitscore: 22.3, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATKKEILSRLNNNFAKLTPGGIREFDYQVSTIPGIIKLTLGEP
                     DFNVPNTMKQAAIDSINANDSHYAPGNGTLALRQAIAHFMQDRYQLDYDPENEIAVTVG
                     ATEGIFASLSTTINPGDEIIIPTPTFPFYIAVTKILGGIPIEVDTSSDDFVLTPARLQS
                     ILEEHPNAKGLILNYPSNPTGVTYTQDQIKALADTVKSTSLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     GAAFGTDEGKTATQEMKEAYKQRRDFVVNSLQKLGFELINPQGAFYVFAKIPEQYGNDD
                     LKFATNLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIAAFINKED"
     aSDomain        1915..2967
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_46_Aminotran_1_2.1"
                     /evalue="3.60E-72"
                     /label="ctg28_46_Aminotran_1_2.1"
                     /locus_tag="ctg28_46"
                     /protein_end="387"
                     /protein_start="36"
                     /score="235.2"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPNTMKQAAIDSINANDSHYAPGNGTLALRQAI
                     AHFMQDRYQLDYDPENEIAVTVGATEGIFASLSTTINPGDEIIIPTPTFPFYIAVTKIL
                     GGIPIEVDTSSDDFVLTPARLQSILEEHPNAKGLILNYPSNPTGVTYTQDQIKALADTV
                     KSTSLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAGAAFGTDEGKTATQEMKEAYKQRRDFVVNSLQKLGF
                     ELINPQGAFYVFAKIPEQYGNDDLKFATNLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             2996..3991
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 300.4; E-value: 1.8e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_47"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTAGV
                     DGLVIQQRSKVPATIYEKLHANGLKQIATRTAGFDMVDVKKANENGLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSTEIHTATVGIIGVGRIGGTLAKL
                     LHALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPTSKGLLTANDFAM
                     MKPTAGLVNASRGPVVNTADLVAALKKGTIAAAALDTFEGEETVAATDRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLNDVMTILNEGKSPHEITL"
     CDS             4059..4487
                     /locus_tag="ctg28_48"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             4640..4825
                     /locus_tag="ctg28_49"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYVYLLLLFLWIAPFSDGSLPLDESLLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(5001..7151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 330.6; E-value:
                     3.1e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_50"
                     /sec_met_domain="TIGR01193 (E-value: 1.7e-276, bitscore:
                     911.6, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.3e-39, bitscore:
                     126.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYPHYVAQVDEADCGVAALAMILHNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVTPIQADISLFNDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFGRLWSGVSLLFSPAKGYTPQKEPLAGLMTMFRQLTNY
                     KKDISGIIIAALLITLISIVGSYYLQLIIDRFIPSKNIDGLAILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAVLVIQGRLSIGTLMAFNALLAFFISPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDTEKADTNSQDQVDLVGPINIHHVDYSYEYSRPILQDINLQIGCNDKLTIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQLPQLFSGTIKDNL
                     LMGLDREVSAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALL
                     TSARVLIFDESTSSLDPITEKRIVENLLEIEDRTMIFIAHRLSIAKKVNKVVVMRDGKI
                     IEQGTHQELLNYHQEYYNLWNA"
     CDS             complement(7230..7415)
                     /locus_tag="ctg28_51"
                     /transl_table=11
                     /translation="MVKVRINKQFYKDFNFYFYMLFIVLWIKPLIDAENGYELTYCLVF
                     LVGAIIATLLTIFKNK"
     CDS             complement(7428..7586)
                     /locus_tag="ctg28_52"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVKDVVNSLNKWAQSCYAG
                     YKDSPFH"
     CDS             complement(7825..8592)
                     /locus_tag="ctg28_53"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QKVIDSIKDEAYLAILDIELDNQLSGIDVAEQIRKKAEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGKQIESIADRLRIDIDEAYARYQNYMNSNQKHQEKFTYEPTHGVKRQVDF
                     ENLYYIESVKNTNRRLRIVGKDIRIEYRGELGQINNKHLLKVNQSTLINPKAIQEFNRK
                     ERVVYFDENQEIKITVSYRKIKSLINFLEKENH"
     CDS             complement(8600..9907)
                     /locus_tag="ctg28_54"
                     /transl_table=11
                     /translation="MIKLTIFQAFINSFSNIFEIIIIYRLMISSPVGKSILHDILWSLI
                     IISIPLITIGSINLVFLVIYLFLFDQIRSNKNKVMDSILAMFTAVIMSSLFDLVDHYTH
                     TLLLQKKSDLSLWGWLIPLNDFLTTLLIGILVVKIIRPRISWLMTSLSRPTWLWRITAI
                     LFMLYIWLTAIMEKNGIANRYASMLLIVYFIIIIVSAIGFIDFMRTSKRAQQQQQIIDK
                     YQAQITNANQMNQQYNEIRRERHDLRNMLLSIQGYIRDHKDKEAEKLLSTFLQNDTTEK
                     HYDEVDLALDKIKISGLHNLIKEKAYKIVEKGIPFSFEVNAEIDKLPGSEIKTARIIGI
                     LMDNAIEATFKQTKPYIQFALLKHSPKVYELVIANSIEQKLNINTALKFEHSTKEGHQG
                     IGLSNVTQLVENDDHYSFSAEVKDKVVMMTCFIQRK"
     CDS             complement(10040..10204)
                     /locus_tag="ctg28_55"
                     /transl_table=11
                     /translation="MVDLDLETKKNLVIINLFYIGLIALYCILHAGPLNFLVFLGMLVI
                     ANVAEILIG"
     CDS             complement(10328..11722)
                     /locus_tag="ctg28_56"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLCLLVLVVGCMTIHQRRHFNKNVKIDNVSVGG
                     LTAKQALKKLQDNPQSPKIYVNNELVFTDKQSVAKFSSADEQKIENALHSQYTFFPSSK
                     AKNIAIKPQNVNQDEVSKIDQAVSQKVTELNNGRKAPVDAYAVYENGRVQVKPAVGGTQ
                     YSLDGLHNKLEKEVAGGTVRLKPKYTAPLSANSKTVQNEKAKLEELSKRTVTYQVQNKK
                     YQLNCGEIITRATYQNGKYHFDTGAANSKIDEINNTQATLGKSFEFKTHDGSVIKTTAA
                     GSYGWKISKKQAGKTLTNALVANKQTVNAKNDIYGKGYNQQGTGYNTTSNNGIGDTYAE
                     VSLADQHAWFYKNGKCVLSTDIVSGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVQYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFSDLHKN
                     EPVVIY"
ORIGIN
        1 ctaagtgagc agcggtcata tcgattaagt cgatagcctt gtcaggtaat gcgcgttgtg
       61 gcatgtattg aacagagtaa tcaacagcag cttggagaac gtcatctggt aactttacat
      121 tgtggtgacg ttcgtacaag tcacgaatac ctttaaggat ggccactgta tcagccttac
      181 ttggagcatt aacagtaaca gaattgaacc gccgtgctaa tgcagcatcc ttcataatag
      241 tgtttcggta ttcatcttga gtagttgcac cgataactgt tagttcacca cgggataatg
      301 ctggcttaat aatgtcagac atacctttag aaccactaga atcaccagtt gaaccggcac
      361 cgataatttg gtgaatttca tcgaagaaga gaataatgtt tccagccttc ttgacttcat
      421 caaccaactt ttgcatgttt tcttcaaagc taccacggta ttgggtacct gcttcaagac
      481 cagaaatatc aatactgata atttccttgt ccttgatagc agctggcaca tcgccggaaa
      541 caattgcttg tgctaatcct tcaacaacag cagtcttacc aacaccagcg tccccaacta
      601 atacagggtt gttctttgtc cgccggctta aaatttcagc tgtttcttgg atttccttgt
      661 tacgaccaat aacagggtca agttcatgtt cacgagcttc ttgagttaaa ttccgaccta
      721 acttgtgtaa gatactgtcc ttacctgcgt taggttgagg gccaggttga ccaccttgtt
      781 gaggatttgc accgcctggc aattgaccag ttctacgata ttcagcaaat tcttctggtg
      841 ttacttcacg accattgatt aggtaacgcc gattatcaga attgaaacca ttcatgccac
      901 ccattaattg attaaagatg tcattcatgt cgttgtcaaa tggattcatt gggttttgag
      961 ccatatgcaa tccctcctca attaaatata atattttatt ttctaagttt cgtagtctaa
     1021 gtattctgaa agccaaaagt taacacactt gacttcctgt ggctacagca aaaccacaat
     1081 ctcattcgag gtaatgctct tctagttctt taaggacctc ccacatgctc ttgtcctgag
     1141 cgcgagccaa ggcgtcaaga tcacgcaggt taagcgacgt cgaactagac tgtggtttgt
     1201 taaacgattt gtgtaaagtc gtgtagccgt aaccggaacg cttggaaact tgataaatgg
     1261 tcaagtggtt aacttccaaa taatgtttga tgtcgatccg cattgctacc cacttccttt
     1321 acgattaata ttatatcaca tttgtgtagt aagacaacaa aaaagacaca aaaaaattaa
     1381 aaaaattgta ggatataaat ttaatattaa attaaaggcg aactaataat cacaaacatt
     1441 ttcgctcttt gttatattta catttgtaac caataaataa ttttgtaatt aatagttttt
     1501 ttcaaacacc gcttgacaaa aattaaaaaa caattagaat tattaataat cagttaatca
     1561 aaaggaggac acaatgatga tcactgcgac aattcacttg aatcaagcgt atgtcttctg
     1621 gtttagcgcg attaccgtcc gctaaccagc agtgattttg tcattgtggc gttctcggat
     1681 gacccccaaa catccgagag cctcttttat actcattcca atctgatcaa gaagccctgg
     1741 atgttattcc gatagcattt agggcttctt tttctaaatt tacatattat ataggaggaa
     1801 attatcatgc cagctactaa aaaagaaatt cttagtcgtc ttaacaataa tttcgctaaa
     1861 ctcactcctg gcgggatccg cgaatttgac taccaagtca gtacaatccc tggcatcatt
     1921 aagctaacat taggtgaacc agactttaat gtgccaaaca caatgaagca ggccgcaatc
     1981 gatagtatca atgccaatga ttcacactat gctccgggaa atggaacctt agcactacgc
     2041 caagcaatcg cccacttcat gcaagatcgt taccagctgg actacgatcc ggaaaatgaa
     2101 attgcggtta cagttggcgc aacagaaggg attttcgctt ctctttctac tactattaat
     2161 cctggcgacg aaattatcat tccaacccca actttcccct tctatatagc tgtcacaaag
     2221 attcttggtg ggatcccaat tgaagttgat acaagcagcg atgattttgt tctcacaccc
     2281 gcaagactcc aaagcatact agaagaacat cctaacgcaa agggactaat tcttaactac
     2341 ccttctaacc caactggtgt tacttatacc caagatcaaa ttaaagcact cgccgatacg
     2401 gttaaatcaa ctagcttgat tgtaattgca gatgaaattt actctgaact tgtttacgga
     2461 gctactcata cttcaatcgc taattacatc cccgaacaaa cgctaatttt aaatggtgcc
     2521 tcaaagtcac atgcaatgac tggttaccgg attggtttta tcgctgggcc acaagaattg
     2581 atgaaatcag tcagtgccat tcacgcgatg ttagtaacgg ctgcttctaa tccagcaatg
     2641 gccgctgcag gagccgcatt tggtactgac gaaggaaaaa cagctactca agaaatgaaa
     2701 gaagcctata agcaacgacg agatttcgtt gttaatagcc tccaaaaatt agggttcgag
     2761 ctgattaatc ctcaaggagc cttctacgtt tttgccaaga ttcctgaaca atatggtaat
     2821 gatgacctta aatttgcgac aaatcttgcc aatgaaggaa aagttgctgt gattcctggt
     2881 tctttctttg gagctggtgg ccaaggatat gttcgaatta gttacgcaac cagtatggaa
     2941 aatctaaccg gagctcttga taacattgcg gccttcatta ataaggagga ttaacatgac
     3001 aaaaatctta atgacaagtg tgcgggacga tgaacaaacc gccattaacg aatacgcaaa
     3061 agaacataat atcgaaatca tcacaacgcc gaaattgatt gacgatgctg ttgaattaac
     3121 tgccggtgtt gatggactcg tgattcagca acgtagtaaa gttccggcta ctatttatga
     3181 aaaactacat gctaatggtc tcaaacagat tgcgacccgg acagctggtt ttgacatggt
     3241 cgacgtcaaa aaggctaatg aaaatggtct agtcgtgacc aatgtcccag catattcacc
     3301 gcgaagtgtc gctgagtttg cattaatgca gatattccgg ttacttcgga aaacttaccg
     3361 ctttgaccat caagtcgccg aaaatgactt ccgctggttt agcgatgaac aatcaacgga
     3421 aattcatact gctaccgttg ggattattgg tgttggacgc attggcggaa ctctagcaaa
     3481 actccttcat gcattaggtg ctaccgtttt aggatatgat acgaatccgc gcactgacct
     3541 cgatggcatt gtccagtttg tttctaaaga agagctacta aaacaagccg atgttgtcag
     3601 cctccatgtc gatttaaatc cgacttccaa agggttactg actgctaacg actttgcaat
     3661 gatgaaacca actgccggtt tggttaatgc tagccgtggt ccagtcgtta atacagctga
     3721 tttagttgcg gcccttaaaa aaggaacaat tgcagcggct gcccttgata cttttgaggg
     3781 tgaagaaacg gtggcagcta cagatcgtcg agaaaaaggg cttgatgacc agccacttgt
     3841 taaagaactt cacgaaatgg ataatgttat tcttactcct catatcgctt tctttactaa
     3901 tttagctgtc aaaaacatgg tagatatttc tcttaatgat gtaatgacaa tccttaatga
     3961 aggaaaatca ccacatgaaa tcaccttata attgagcacc ctcattgacc aaaagtatcg
     4021 tctcgattac actatgggta ttaaaggagg gaacgggtat gagtaaatat aaagtaacag
     4081 cgactaagac aacaacggga atgcaggttt cagcaggtac ccgcggtttt gaaatcacct
     4141 ttgatgaacc tgaaagtaca aatacgggga tgaacccagt agaaattctc ctcgcatcat
     4201 ttggtgcctg ccaggcaatc actgcccaag cattagctaa aaaacgcaac tttgacctac
     4261 gagctttttg ggtaacaatc gagggtgatc ttggtcgtga agatgttgct gatggtaaga
     4321 atgttcgtaa atttactgag atccgttacc aaccacacct tcgcagcagc gagtctgatg
     4381 aagacatcaa gaagttcctc gctgacgttg ccgcaaagtg tcccgtggaa aacactctga
     4441 cctacggaac gaaatttgtt caagatggat ttgtaaaagt tgattagttg aaaaaacgcc
     4501 ttggaatttt ccagggcgtt tttctaaata gtcaacctat acgaattctg caagaaactt
     4561 aacgaatttt gcaaagtgtc ctttaaatta gatctttcct tataattaag gtacacatac
     4621 tgtcttaggg ggagaactaa tgaaaattca cttcaataag gacttttggc gggatggttt
     4681 cttttatgtg tacttattac ttttgtttct ctggattgct ccattttcag atggttcgct
     4741 tccattagat gagtcgctac tatgtatctt ctttataatt tttactatcg gttccatgct
     4801 cgcaattatg tttaataaag actgagaaag gactgtgaca taagttaagt tactttcata
     4861 aaaagcaaat acgcagtaca acaatggcct ctaacatccg gcaaaaccga acgttagagg
     4921 cctattgttg cttgcggggg ctcccagagg ctagcttcgc gtcgaaaaac gaagtcacaa
     4981 gtgacttctg tctcgctccc ttatgcattc cacaaattat agtattcttg atgataattc
     5041 aaaagttctt ggtgagtacc ctgttcaatg atttttccgt cgcgcattac tactactttg
     5101 ttgacctttt tagcaattga aagacggtgg gcaataaaaa tcattgtgcg gtcttcaatc
     5161 tcaagcaaat tctcaacgat tcttttttca gtaattggat ccaaactact tgttgattca
     5221 tcaaaaatta aaacacgcgc agaagttagg agtgcccgtg caatcgtcaa gcgttgtttt
     5281 tgaccaccag ataatgcagt tgcttcttca tctagttttg tttcatattt taggggcatt
     5341 tcttgaatat cattatagat taatgccaat ttacatgcat tatcgatttc ttcagctgat
     5401 acttcccggt ctaatcccat tagcaagtta tctttgattg ttcccgaaaa taattgtggc
     5461 aattggggta agtaatgtac atattgtcta atatcgcaaa gattaatctc agttgtttta
     5521 tgctgattaa attctatctg tccttgagta ggtaaataaa agccaactaa taactttgcc
     5581 aaggtcgatt taccagaacc gctcaatcct acaattgtca atttatcatt acaaccaatt
     5641 tgaagattga tatcctgtaa aattggacga ctatattcat atgaatagtc aacatggtga
     5701 atgtttatcg gacctaccaa atctacttga tcctgagaat tcgtatctgc cttttcggtg
     5761 tcaacttgca gcacttcatt taatcgatta ttcgccactt tagcttcttg gagtttaggt
     5821 tgaagattaa taatattttg taatggactg ataaaaaagg ctaataacgc attaaaggcc
     5881 atcaatgtcc cgatacttaa gcgaccctga attactaaaa ctgctccttg aaaaagaatg
     5941 attgttacta agccgtattg aatccacatt ttaattgcat cctgaaaaga tttagtttta
     6001 acatatgtta gattctttcg taagaaatcc gcaaattgtt tttcaacatt tttataacgg
     6061 atattttcaa gttgcagcac tttcaacgtc tctacgcctt ttaaatcctc aataattgct
     6121 gaacttaatt gagcgttact ctccatttgt tcttgatcca gtttagcaaa gcgcttatta
     6181 aaggcataaa tgataatgac ataaatcgga atggtactaa ttgtagttaa aaataatgac
     6241 cgatcgtaca aagaaagaac aattcctata atcaccatca cgccaacgtc taagaacatt
     6301 gaaataatag tgcttgataa ggcatcaata atcttattaa tgtcattgaa ccgtgaagta
     6361 atttcccccg tttttcttgt agagaaaaat ctcatcggta aacgataaac atggtgaata
     6421 tatctaagac ttatttgtga tgttagtttt tgatccaacc tagtcaagag aacatctcgt
     6481 aaatagttaa aaagagagtt gaacacatag actaccaata aactaccagc aaggatcgct
     6541 aagccatcaa tatttttcga gggaataaaa cgatcaataa ttaattggag atagtatgat
     6601 ccaacgatgc tgatgagggt aattaataat gccgcaatga taattcctga tatatctttt
     6661 ttataattag ttaattgtcg aaacatcgtc attaacccag ctaaaggttc tttttgcggt
     6721 gtatacccct tagcaggcga aaaaagtaaa cttacacctg accataaacg accaaactca
     6781 tcccgagtca ttttttgtac tttcgtagca ggatctggat cagctacata gatgtaatct
     6841 tggtcagcct taaaaacgac acagtaatga agtaaatcat ccttaatcac atgtgcgatt
     6901 aacgggtaag taatttcagg atcattaaac aatgatatat ctgcttgaat gggggtaacg
     6961 tctaatccaa gatgttttgc tgcttttaca agtcctaagg cggtagttcc ttgcttagtt
     7021 gtccgtgcta agtcacgtaa ttttgcgatt ggataaacag acccaaaatt gtgcaaaatc
     7081 attgctaaag cggcgactcc gcaatctgcc tcatcaactt gagctacata atgaggataa
     7141 ttgattttca ttcacctcgc tttctaatta gacaaagaaa taaagtccaa aattaataat
     7201 tattctgggc tttatattct cataagatac tatttatttt taaatatggt taataaagta
     7261 gcaattattg ctccaactaa gaaaactaag cagtaagtaa gttcataacc attttctgca
     7321 tctattaacg gtttaatcca aagaacaata aataacatgt aaaaataaaa attaaaatct
     7381 ttgtaaaatt gtttattaat tctcactttt accatcttct cctcttatta gtgaaatgga
     7441 ctatctttat agcctgcgta gcaagattga gcccatttgt tcaaggaatt aacaacatct
     7501 ttaactagtt cattaacctg tgaagagaga ctccatccac cagaaacctt gcttaattca
     7561 tcgaagttta atttacgata agtcatttta attacctcct gatacgataa agttaggatt
     7621 ttaacattat gttccaatgc ataatacttt accttgatcc cacccttagt atataagtaa
     7681 aaattttctc tgtgtcattt tgcaaaattc gtaagccttt ctgcagaatt cgtagtaaaa
     7741 ttcttgaaaa cgtttactaa aattgtttga caaaaaaaga aaccacgaca gctttttgtc
     7801 acagtttctt tgaaaataaa atagttagtg attttccttt tcaagaaaat tgattaatga
     7861 ttttattttt cggtaactaa cagttatctt aatttcctga ttttcatcaa agtaaaccac
     7921 acgttcttta cgattaaatt cttggattgc tttgggatta atcagcgtac tttgattcac
     7981 tttcaataaa tgcttgttat taatttgacc taactcgcca cgatattcaa tccgaatatc
     8041 ttttcccaca atccgtaacc gtcgatttgt gttttttact gattcaatat aatagagatt
     8101 ttcaaaatca acttgccttt ttactccatg agtcggttca taagtaaact tttcttgatg
     8161 tttttgatta ctattcatgt aattctgata gcgagcatat gcttcatcaa tatcaatccg
     8221 gagacgatcc gcaattgact caatctgctt accctttgat atataatcaa atggctcaat
     8281 tcggcgcgaa acagtataag gtaaatattc ttgataagca gttacaaaga taatttcggc
     8341 aaattcagct tttttgcgga tctgctccgc aacatcaatc ccactaagtt gattatctag
     8401 ttcaatatct aaaatcgcta aataagcctc atctttgata ctatcaatca ctttttgcgg
     8461 atcatttgtc cgcaaatata attcgatgtc ataactattt ggagtagcat taatcaattt
     8521 tcgctgagaa actaggcgct cagtataatc agcttgataa tcatcatttt ccaaaataat
     8581 tacttttaac attttattct cactttctct gaataaaaca agtcatcata actaccttat
     8641 ctttaacttc cgctgaaaaa gaataatggt catcattttc taccaactgt gtcacatttg
     8701 aaaggccaat tccttgatgc ccttctttag tcgaatgttc aaattttagt gcagtattaa
     8761 tattaagttt ttgctcaatt gaattagcaa ttaccaattc ataaactttt gggctgtgct
     8821 taagcaatgc aaactgaata taaggtttag tttgcttaaa ggttgcttca attgcattat
     8881 ccattaaaat tccgatgatt ctagcagttt ttatttcgga acctggtaac ttgtcgatct
     8941 cagcattaac ttcaaacgaa aatggaatac ctttttctac tattttataa gccttttcct
     9001 taataagatt atgtaagcca gagattttga ttttatctaa ggccaagtcg acttcatcat
     9061 agtgcttttc ggttgtatcg ttttgcaaaa atgttgacag caacttttcg gcttctttat
     9121 ccttatggtc acgaatataa ccttgaatac tgaggagcat atttcgtaga tcatgtcgtt
     9181 cccgtcgaat ttcattgtat tgttggttca tctgattggc attggtaatc tgtgcttggt
     9241 atttatcaat gatttgttgt tgctgctgag ctcgcttgct tgtacgcata aagtcaataa
     9301 agccaatcgc actcacaata ataatgatga aatatactat tagtaacata gaagcgtatc
     9361 tattagcaat tccatttttt tccataattg ccgtcaacca gatatataac ataaataata
     9421 ttgctgttat cctccataac caagttggcc ttgaaagact agtcattaac caactaatac
     9481 gaggacgaat tatttttaca acaaggattc cgattagaag ggtcgtcaaa aagtcattaa
     9541 ggggaattaa ccatccccat aatgataagt ctgatttttt ttgcaaaagc aaagtatgag
     9601 tatagtgatc aactagatca aacaatgatg acattataac tgccgtaaac attgctagaa
     9661 tactatccat aaccttattt ttatttgatc ttatttgatc gaataaaaat aagtaaatta
     9721 ccaaaaatac taagttaata gatccaattg ttattaatgg aatactaatt ataattaaac
     9781 tccataatat atcatgtaat atagattttc caactggact acttatcatt aaacgataaa
     9841 taattattat ttcaaagatg ttagaaaaac tattgataaa agcttgaaat atagttaatt
     9901 tgatcatctt ttattccaat aggggaaaag atatctccaa tctctattaa atctatggct
     9961 acgtccacca taaattttta ctaaaaaagt ttttgacagt attttatact tactacgcac
    10021 catattgcct gtccctcctc tatccaataa gaatctctgc tacatttgca atcactaaca
    10081 ttcccaaaaa cactaaaaaa ttcagtggcc ctgcatgcaa aatacaatac aaggcaatca
    10141 atccgatata aaaaaggtta atgattacca aatttttctt cgtttctaaa tccaaatcca
    10201 ccatataact aactcctact ttatccatcc ctctgataat gcaaaagaaa taataatcgt
    10261 taaaacaaag caagctattg caatcataat tgcgcgttca gcactcgggc gcacaacatc
    10321 tcctccttta gtagataacc acaggctcat ttttatgtaa gtcactaaaa gcttgaccag
    10381 ctacgtctgg atgcatgtta atacaaccgt gcgatccacc gcctttagca agataagcct
    10441 gttttgacca atcgtgacgc caacttgcat catgaaatcc acatccacta tcagtaaatg
    10501 gtgaccaata ttgaactttg ctagcgtatt tcgaaccatc atcattaagg ccccgaagaa
    10561 cagacggtgt ttgctggtac atgatatacc agacgccttt tggcgtctca ttatctttgt
    10621 tattggtccc actaacaatg tcagtgctaa gaacacattt accattctta tagaaccacg
    10681 catgttggtc ggctagtgaa acttcggcgt aagtgtcccc tataccattg ttgcttgtag
    10741 tattataccc agttccttgt tgattataac ccttaccata aatatcattt ttggcgttta
    10801 ctgtttgctt atttgcaacc aatgcattcg taagagtctt tccagcttgt tttttactga
    10861 tcttccaacc atacgagcca gcagccgttg ttttgatcac tgatccatca tgtgttttga
    10921 attcaaatga tttgccaagg gttgcttggg tattattaat ttcatcaatc tttgaattag
    10981 ctgctccagt gtcaaagtga tattttccat tttgatatgt tgctctggta ataatctcac
    11041 cacaatttaa ctgatacttt ttgttttgta cttggtatgt tacagttcgt tttgataatt
    11101 cttcgagctt tgctttttca ttctgaacag ttttactatt tgcagaaagc ggagccgtat
    11161 attttggctt cagacgaact gttccaccag caacttcttt ttcaagctta ttatgcaaac
    11221 catccaaact atattgagtc ccaccaactg ctggttttac ttgtactcgg ccattttcgt
    11281 atacagcgta agcatcaaca ggagcttttc gaccattatt taattctgtt accttttgac
    11341 tgactgcttg atcaatcttt gatacttcat cttgattaac attttgaggc ttaatcgcaa
    11401 tgttctttgc cttagatgat gggaagaaag tatactgact atgtaatgca ttttcaattt
    11461 tttgttcgtc agcactacta aactttgcta ctgattgctt atccgtaaat actaactcat
    11521 tgttaacata aatttttggc gattgtggat tatcttgtaa cttctttaat gcttgcttag
    11581 cagtcaatcc accaaccgac acattatcaa tcttaacgtt cttattaaaa tgacgacgct
    11641 ggtgaatagt catgcagcca accaccagca ctaataagca caatgtgatt attattagtt
    11701 gtttaataga tagtttttgc ataaaagtac tccaataaca tccaaatagt taagtataat
    11761 ttctatactt aatgatcatt ttgtaaacat attcattacg ctcattcatt atatactaaa
    11821 gcgtaaacaa ttagtatatt ttacattttt catagtattt tactaaaaaa gcgtctggca
    11881 aaaataccgg acacttttta ataaccaaac tatttagcgg ttgtaacttg atattgacca
    11941 ttaccatttg ctttatagta aacagtttga cccttgtagg ttacagaacc attaccttcc
    12001 ttggcatttt tgtaaaactc ttcaacagat gtattattat caatcacgcc cgctttttgc
    12061 gcagcccggt agctaaagtt catcccatct tccactgtta caggttgttg agttgatgca
    12121 gcttgggttg tctttcggct tactgtccgc c
//
