LOCUS       c00013_JAJGUE0..       12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGUE010000312.1 Limosilactobacillus reuteri strain apa71
            scaffold312, whole genome shotgun sequence.
ACCESSION   JAJGUE010000312
VERSION     JAJGUE010000312
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 11:27:16
            Original ID  :: JAJGUE010000312.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2166
            Orig. end    :: 14317
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[7166:9317](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7151
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             406..1800
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLGLLVLVMGLMTIHQRRHFNKNVKIDNVAVGG
                     LTAKQALKKLQDNPQTPKVYVNNDLVYTGKQPVAKFTQADEEKVANALHRQYTFFPSNK
                     EKNLLIKPQKFNQSVVPQVDQAVSQKVTELNNGRKAPINAYAVYENGQVQVRPAVGGTQ
                     YSLDGLHNQVEKELVQGAVKLKPIYKAPLSAKSKTVQNEKTKLEQIAKRDVTYQVQGKK
                     YHLTSADIITRATYQDGKYHFNTKVLGTKIDEINNQQATLGKPFEFKTHSGSMIKTTAA
                     GSYGWKISKKQAGKTLTDALVANKQTVNAKNDIYGKGYNQQGTGYNNTSNNGIGDTYAE
                     VSLADQHAWFYKDGKCVLSTDIVSGTNNKGNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVQYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFHDLQKN
                     EPVIIY"
     CDS             1814..1912
                     /locus_tag="ctg13_5"
                     /transl_table=11
                     /translation="MRPSAERSIMIAVVCFILTIIISFALSEGWIK"
     CDS             1923..2081
                     /locus_tag="ctg13_6"
                     /transl_table=11
                     /translation="MDLEKKKNLVIINLFYVGLILIYCILHAGPLNLMVFLIMLIIANL
                     VGILSNN"
     CDS             2110..2241
                     /locus_tag="ctg13_7"
                     /transl_table=11
                     /translation="MLEKKYKILTKKELLKLYGGWGYSLAFRDTRSWERAVLKWIKR"
     CDS             2238..3551
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MIKLTVGQGLVSSISNIIEIIFIYRLVTKSLSLKLIIIDSLAVLM
                     MIFFSVIFMMLGSLYPVLIVFYLWLVDRIKSNSCIAINSILAICTSIIMSSLFDLVDHY
                     TYTFFVQGKAHVSLLGWLIPLNDCILTFIVSVFVIKIIYPEIKWVYIKFPNPIQLWKIT
                     AIYFVLYIWLTTIAEKEEIADKYASLLLIMYSIIIIVSVTGFLTFVKNNEQTQHQQRLI
                     NDYQSQIANAHKINKHYNEIRRERHDTRNMLLSIQGYIRDHKDKEAEELLATFLQNDTV
                     EKHYGEIDNALDKIKISGLHNLIKEKAYKIVEKGIPFSFEVNAEIDKLPGSEIKTARII
                     GILMDNAIEATFKQAKPYIQFALLKHSPEVYELVIANSIEQKLNINTALKFEHSTKEGH
                     QGIGLSNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             3559..4326
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QKVINSIKDDAYLAILDIELDNQLSGIDVAEQIRKKAEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGKQIESIADRLRIDIDEAYARYQNYVSSNQKHHEKITYEPIRGVKRQVDL
                     ENLYYIESVKNTNRRLRIVGKDIRIEYHGELNQVDSNHLLKVNQSTLINPKAIQEFNRK
                     ERVVYFDANREIKVTVSYRKIKSLVDFLEKEDY"
     CDS             4567..4725
                     /locus_tag="ctg13_10"
                     /transl_table=11
                     /translation="MTYRKLNFDELNKVSGGWSLSSQVNELVKDVVNSLNKWAQSCYAG
                     YKDSPFH"
     CDS             4740..4922
                     /locus_tag="ctg13_11"
                     /transl_table=11
                     /translation="MTMKFNHDFYTNLDFYIYIIVTFFWVLAIPKASNIYETIICIACA
                     IIGVFAALRILFKTK"
     CDS             5001..7151
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 331.4; E-value:
                     1.8e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_12"
                     /sec_met_domain="TIGR01193 (E-value: 3.6e-275, bitscore:
                     905.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 1e-38, bitscore:
                     122.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYPYYVAQVDEADCGVASLAMILRNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTWDEFGRLWSGVCLLFSPAKGYAPQKEPLAGLTTMFQQLTNY
                     KKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLAILAGSLLVVYAFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     VISIFLDVGVMVIIGIVLSLYDQSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAVLVVQDRLSIGTLMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDTEKSDTNSQDQTDLIGPISIQHVDYSYEYSRPILQDINLQIGCNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKITEINLCDIRQYVHYLPQSPQLFSGTIKDNL
                     LMGLDHEISAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALL
                     ASARVLIFDESTSSLDPITEKRIVENLLEIEDRTMIFIAHRLSIAKKVNKVVVMRDGKI
                     IEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7184..7369)
                     /locus_tag="ctg13_13"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYIYLLLLFLWIAPFSDGSLPLDESLLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(7519..7947)
                     /locus_tag="ctg13_14"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             complement(8015..9010)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 295.6; E-value: 5.2e-90)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_15"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTADV
                     DGLVIQQRSKVPADIYEKLHANGLKQIATRTAGFDMVDIKKANENGLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSIEIHTARIGIIGVGRIGGTLAKL
                     LNALGATVLGYDTNPRTDLDGIVQFVSKEELLRQADVVSLHVDLNPTSKGLLTANDFAM
                     MKPTAGLVNASRGPVVNTADLVTALKAGEIAAAALDTFEGEETVAAADRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMTILNSKKSPHEITL"
     CDS             complement(9012..10199)
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     1.5e-71. Score: 233.2. Matches aSDomain:
                     nrpspksdomains_ctg13_16_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 272.4; E-value: 1e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_16"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8.2e-08,
                     bitscore: 22.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFAKLTPGGIREFDYQVSAIPGIIKLTLGEP
                     DFNVPAAMKQAAIDSINANDSHYAPGNGTFALRQAIAHFMQDRYKLEYDPKNEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSGDDFVLTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTIKSTNLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKAATQEMKDAYEQRRDFVVDSLQKLGFELINPQGAFYVFAKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIAAFINKED"
     aSDomain        complement(9039..10091)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg13_16_Aminotran_1_2.1"
                     /evalue="1.50E-71"
                     /label="ctg13_16_Aminotran_1_2.1"
                     /locus_tag="ctg13_16"
                     /protein_end="387"
                     /protein_start="36"
                     /score="233.2"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPAAMKQAAIDSINANDSHYAPGNGTFALRQAI
                     AHFMQDRYKLEYDPKNEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSGDDFVLTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTI
                     KSTNLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKAATQEMKDAYEQRRDFVVDSLQKLGF
                     ELINPQGAFYVFAKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             10704..10925
                     /locus_tag="ctg13_17"
                     /transl_table=11
                     /translation="MRIDIKHYLEVNHLTIYQVSKRSGYGYTTLHKSFNKPQSSSTSLN
                     LRDLDALARAQDKSMWEVLKELEEHYLE"
ORIGIN
        1 atatgtatac ggggcaacgg gtcctaattc atttgattgc tctggattgg ttcaatacgt
       61 ttatcgtcag gcaggagtta acttaccacg gacagctgcc caacaatcta accaagggta
      121 cagcgtcagc atgaataact tacaaccagg ggatctctta ttctggggta atccaggaag
      181 tgcataccat gttggaattt acactggaaa tggtaagact ttatttgcac cacaacctgg
      241 tcaaacagta aaagaacaac caatgagtta ctggatgcca aactttgctc gtcgtgtttt
      301 gtaataaaaa tattattttt ttgtttaata tagaaaaccc tactgctata attattagcg
      361 tgtagggcat ttctattatt taacttatta agttggagta cttttatgca aaaattatct
      421 attaaacaac taataataat cacattaggt ttgctagtac tggtaatggg tttgatgacg
      481 attcatcagc gccggcactt taataaaaat gtcaaaattg ataatgtagc ggtcggtggt
      541 ttaacggcta agcaagcact aaaaaaattg caagataacc cgcaaacacc caaagtatac
      601 gtgaacaacg acctagttta tacaggaaaa caaccagttg ctaaatttac ccaagctgat
      661 gaagaaaagg tggctaacgc cttgcatcgt caatatacct tttttccatc taataaggag
      721 aaaaatttgc tgattaagcc acaaaagttt aatcaaagtg ttgttccaca ggttgatcag
      781 gccgttagtc aaaaggtaac ggaactaaat aatgggcgca aagcaccaat taatgcttat
      841 gcggtatacg aaaatggtca agtacaggtt agaccagcag ttggcggtac tcagtacagt
      901 ttagatggtt tgcataatca agtcgaaaaa gaacttgtgc agggagcggt taaactaaag
      961 ccaatttaca aggctccgct ttctgctaag agtaagacag tacaaaatga aaaaacgaag
     1021 ctagaacaga tagctaagcg ggacgtgacc tatcaagttc aaggtaagaa gtaccatttg
     1081 accagtgcgg atatcattac tcgagctact tatcaagatg gcaagtatca ttttaatacc
     1141 aaagtattag gtacaaaaat tgatgaaatc aataatcagc aagctacttt gggaaagcca
     1201 tttgagttca aaactcacag tggttcaatg attaaaacaa cggctgctgg ttcatatggt
     1261 tggaagatca gtaagaaaca agctggaaag actcttacgg atgcattggt tgcaaataag
     1321 caaacagtaa acgccaaaaa tgatatctat ggtaaaggtt ataatcaaca aggaactggg
     1381 tataataata caagcaacaa tggtataggg gacacttacg ccgaagtttc actagccgac
     1441 caacatgcct ggttttataa agatggtaag tgtgttctta gtactgatat tgttagtggg
     1501 acgaataata aaggaaatga gacgccaaaa ggtgtctggt atattatgta ccagcaaaca
     1561 ccgtctgtcc ttcgaggcct taacgatgat ggttcgaaat atgcaagtaa ggtccaatat
     1621 tggtcaccat ttactgatag tggatgtgga tttcatgatg caagctggcg tcatgactgg
     1681 tcgaaacaag cctatctcgc taaaggtggc ggatcgcatg gatgtatcaa catgcatcca
     1741 gatgttgccg gacaagcctt tcacgactta cagaaaaatg agcctgtaat tatctactaa
     1801 aggagaattt cttatgcgcc caagtgctga acgctcaata atgattgcgg ttgtttgttt
     1861 tatattaaca attattattt cattcgcctt gtctgaggga tggataaagt agggatttaa
     1921 cgatggactt agaaaagaag aaaaatttgg taattattaa tctattttat gttggattaa
     1981 ttttaattta ctgcattttg catgcagggc cactgaattt aatggtattt ttgataatgc
     2041 taattattgc gaatttagta ggtatattaa gtaataatta attttaaaat gttatgggag
     2101 gatttagtca tgttagagaa aaagtataaa attttaacaa aaaaagagct actcaaacta
     2161 tacggtggtt ggggatattc acttgctttt agagatactc gttcatggga aagagcagtt
     2221 ttaaaatgga ttaaaagatg attaaattaa ctgttgggca aggattagta tcatctatat
     2281 caaatattat tgaaattatt tttatttatc gattggtaac aaaaagctta tcattgaaat
     2341 taataataat tgactctttg gctgttttga tgatgatatt cttttcggta atatttatga
     2401 tgctaggctc cctttatcca gtacttatag tattttattt atggttagtt gatagaataa
     2461 aatctaactc ctgtatagct ataaatagca ttcttgcgat atgtactagt atcataatgt
     2521 catctttatt tgatttagtg gatcattata cttatacatt tttcgtacaa ggaaaggcac
     2581 atgtatcact tttaggttgg ttaattccgt tgaatgattg tattttaaca tttatagtaa
     2641 gcgtatttgt aatcaagatt atttatcctg agataaagtg ggtttatatt aaatttccca
     2701 accctattca attatggaaa ataactgcta tctattttgt actttatatt tggttaacta
     2761 ctattgcaga aaaagaagaa attgctgata aatacgcttc attactgtta atcatgtatt
     2821 ctataatcat aatagtatct gttaccggct tccttacttt tgttaaaaat aatgaacaaa
     2881 ctcaacacca acagagatta atcaatgatt atcaatcgca aattgctaat gcccacaaaa
     2941 taaataaaca ttataatgag attcggcgtg agcgtcacga tacacgtaat atgcttctca
     3001 gtattcaagg atatattcgt gatcacaaag ataaggaagc ggaggaatta ctagcaacgt
     3061 ttcttcaaaa tgatacagtt gaaaagcatt atggtgaaat tgataatgca ttagataaga
     3121 ttaaaatttc agggttgcat aatcttatta aggaaaaggc ttataaaata gtagaaaaag
     3181 gtattccgtt ttcgtttgaa gttaatgctg agatcgacaa gttaccaggt tccgaaataa
     3241 aaactgctag aattatcgga attttaatgg acaatgcaat tgaagcaaca tttaagcaag
     3301 ctaaaccata tatccaattt gcgttgctta agcacagtcc agaagtttat gaattggtaa
     3361 ttgctaattc gattgagcaa aaacttaata ttaatactgc actaaaattt gaacattcga
     3421 ctaaagaagg gcatcaagga attggtcttt caaatgtgac acagttggta gaaaatgatg
     3481 accattattc tttttcagcg gaagttaaag ataaggtaat tatgatgact tgttttattc
     3541 agggaaagtg agaataaaat gttaaaggta attattttgg aaaatgatga ttatcaagct
     3601 gattatacag agcgcctcgt ttctcagcga aaattgatta atgctactcc aaatagttat
     3661 gacatagaat tatatttacg gacaaatgat ccgcaaaaag tgatcaacag tatcaaagat
     3721 gacgcttatt tagcgatttt agacattgag ctagacaatc aacttagtgg gatcgatgtt
     3781 gctgagcaga tccgcaaaaa agctgaattt gccgaaatta tctttgtaac tgcttatcaa
     3841 gaatacttac cttatactgt ttcgcgccga attgagccat ttgactatat atcaaaggga
     3901 aaacagattg agtcgattgc agatcgactc cggattgata ttgatgaagc atatgctcgc
     3961 tatcagaatt atgtaagtag taaccaaaaa caccatgaaa aaattaccta tgaacctatt
     4021 cgtggtgtaa aacgacaagt tgatttagaa aatctttact atattgaatc agtaaaaaat
     4081 acaaatcgac ggttacggat cgttggaaag gatattcgaa ttgaatacca tggtgagcta
     4141 aatcaagtcg atagtaacca tctattgaaa gttaatcaga gtactctgat taatcctaaa
     4201 gcaatccaag aatttaatcg taaggaacgt gtagtttact ttgatgcgaa tcgagaaatt
     4261 aaagtgactg ttagttatcg aaaaataaaa tcattagttg attttctcga aaaggaagat
     4321 tactaactac tttattttta aagaaactgt gacaaaaagc tgtcgtggtt tcttttttat
     4381 tgtcaaacaa ttttagtaaa cgttttcata acttttacta cgaattctgc agaaaggctt
     4441 acgaattttg caaaatgaca cagagaaaat ttatacttat atactaaggg tgggatcaag
     4501 gtaaagcatt atgcattgga acataatgtt aaaatcctaa ctttatcgta tcaggaggca
     4561 attaaaatga cctatcgtaa attaaacttc gatgaattaa acaaggtttc tggtggatgg
     4621 agtctatctt cacaggttaa tgaactagtt aaagatgttg ttaattcctt gaataaatgg
     4681 gctcaatctt gctacgcagg ctataaagat agtccatttc actaatagtt tataatttaa
     4741 tgactatgaa atttaaccac gatttttaca ccaatcttga tttttatatc tatattatag
     4801 ttacattctt ctgggtctta gcaattccca aggcaagtaa catttatgaa acaattatat
     4861 gtatagcttg cgcgatcatt ggtgtttttg cagctctacg aattttattt aaaactaaat
     4921 agcattttat aagaatataa agcccagaat cattattaat tttggacttt atttctttat
     4981 ctaattagaa agcaaggtga atgaaaatca attacccata ttacgtagcc caagttgatg
     5041 aagcagattg tggagtcgcc tccttagcaa tgattttgcg caattttggt tctgtttatc
     5101 caatcgcaaa attacgtgac ctagcccgga cgactaagca aggaactact gccttaggac
     5161 ttgtaaaagc agcgaagcat cttggattag acgttattcc cattcaagca gatatatcat
     5221 tgtttgatga tcctgaaatt acttacccgt tgatcgcgca tgtgattaaa gatgatttac
     5281 ttcattactg tgtcgttttt aaggctgatc aagattacat ctatgtagct gatccagatc
     5341 ctgctacgaa agtacaaaaa atgacgtggg atgaatttgg tcgtttatgg tcaggtgtat
     5401 gtttgctttt ttcgcctgct aaggggtatg caccgcaaaa agaaccttta gctggattaa
     5461 cgacgatgtt tcaacaatta actaattata aaaaagatat atccggaatt gttattgcgg
     5521 caatgctaat tacttttatc agcatcgtcg gttcatacta tctccaatta attattgatc
     5581 ggtttatacc ttcgaaaaat attaatggct tagcgatcct tgctggtagt ttattagtag
     5641 tttatgcgtt taattctctt tttaattatc tgcgagatgt tctcttgact aggctggatc
     5701 aaaaactgac atcacaaata agtcttagat atattcacca tgtttatcgt ctaccgatgc
     5761 gatttttctc cacaagaaaa acgggggaaa ttacgtctcg ttttaatgat attaataaga
     5821 ttattgatgc cttatcaagt actgttattt caatattctt agatgttggc gtgatggtga
     5881 ttataggaat tgttctttct ttgtatgatc agtcattatt tttaactaca attagtacca
     5941 ttccgattta tgtcattatc atttatgcct ttaataagcg ctttgctaaa cttgatcagg
     6001 aacagatgga gagtaatgct caattaagtt ctgccattat tgaggattta aaaggcgtag
     6061 aaacgttgaa agtgctgcaa cttgaaaata tccgttataa aaatgttgaa aaacaatttg
     6121 cggatttctt acgaaagaat ctaacatatg ttaaaactaa atcttttcag gatgcaatta
     6181 aaatgtggat tcaatacggc ttagtaacaa tcattctttt tcaaggggcg gttttagtag
     6241 ttcaagatag attaagtatt gggacattga tggcctttaa tgcattatta gccttttttg
     6301 tcagtccatt gcaaaacatt attaatcttc aacctaaact ccaagaagct aaagtagcga
     6361 ataatcgatt gaatgaagtg ctgcaagttg ataccgaaaa gtcagatacg aattctcagg
     6421 atcaaacaga tttaataggg ccgataagca ttcaacatgt tgactattca tatgaatata
     6481 gtcgtccaat tttacaagat atcaatcttc aaattggttg taatgataaa ctggcaattg
     6541 taggattgag cggttctggt aaatcgacct tggcaaagtt gttagttggc ttttatttac
     6601 ctactcaagg gcagatagaa tttaatcagc ataaaataac agagattaat ctttgcgata
     6661 ttagacaata tgtacattac ttacctcaat cgccacaatt attttcggga acaatcaaag
     6721 ataacttgtt aatgggatta gatcatgaaa tatccgcaga agaaatcgat aatgcatgta
     6781 aattggcatt aatctataat gatattcaag agatgccctt aaaatatgaa acaaaactag
     6841 atgaagaagc aaccgcatta tctggtggtc aaaaacaacg cttgacgatt gcacgagcac
     6901 tcctagcttc tgcgcgtgtt ttaattttcg atgaatcaac aagtagctta gatccaatta
     6961 ctgaaaaaag aatcgttgag aatttgcttg aaattgaaga ccgcacaatg atttttattg
     7021 cccatcgtct ttcgattgct aagaaagtca ataaagtggt agtaatgcgc gacggaaaaa
     7081 tcattgaaca gggtactcac caggaacttt tgaatcatca tcaagaatac tataatttgt
     7141 ggaatgcata aaaggctccg aacattgctg ttggagcctt ttttcagtct ttattaaaca
     7201 taattgcgag catggaaccg atagtaaaaa ttataaagaa gatacatagt agcgactcat
     7261 ctaatggaag cgaaccatct gaaaatggtg caatccagag aaacaaaagt aataagtata
     7321 tataaaagaa accatcccgc caaaagtcct tattgaaatg aattttcatt agttctcccc
     7381 ctaagacagt atgtgtacct tattataatg aaagatctaa tttaaaggac attttgcaaa
     7441 attcgttaag tttcttgcag aattcgtata gattaactat taaaaaacgc cttggaaact
     7501 cccaagacgt tttttcaact aatcaacttt tacaaatcca tcttgaacaa atttcgttcc
     7561 ataggtcaga gtgttttcca cgggacactt tgcggcaacg tcagcgagga acttcttgat
     7621 gtcttcatca gactcgctgc tgcgaaggtg tggttggtaa cggatctcag taaacttacg
     7681 aacattcttg ccatcagcaa cgtcttcacg accaagatca ccctcgattg ttacccaaaa
     7741 agctcgtaaa tcaaagttac gttttttagc taatgcttgg gcagtgattg cttggcaggc
     7801 accaaatgac gcaagaagaa tttctactgg attcatcccc gtattagtac tttctggctc
     7861 atcaaaggta atttcaaaac cacgggtacc tgctgaaact tgcatccccg ttgttgtctt
     7921 agttgctgtt actttatatt tactcataac cgttccctcc tttaataccc atagtgtaat
     7981 tgagacgata cttttggtca atgagggtgc tcaattataa ggtgatttca tgtggtgatt
     8041 ttttgctatt aaggattgtc atcacatcat caagtgaaat atccaccata tttttgactg
     8101 ctaaattagt aaagaaggca atgtgaggcg taagaatgac attatccatt tcatgtaatt
     8161 ctttaacaag gggctgatca tcaagtcctt tttctcggcg gtccgcagct gcaactgttt
     8221 cttcaccttc aaaggtatcg agggcggccg cggcgatttc cccagctttt aatgctgtga
     8281 cgaggtcagc tgtattaacg actggaccac gactagcatt gaccaaacca gcagttggtt
     8341 tcatcattgc aaagtcgtta gcggtcagca aacctttaga agttgggttt aaatcgacgt
     8401 ggagactaac aacatcggct tgccttagta attcttcttt agaaacgaac tggacaattc
     8461 catcgaggtc agtgcgcgga ttcgtgtcat aaccaagaac agtggcaccg agggcattga
     8521 gaagtttagc aagtgttccg ccgatacgcc cgaccccaat aattccaatc cttgccgtgt
     8581 gaatttcgat tgactgttca tcgctaaacc agcggaagtc attttcggcg acttggtggt
     8641 caaagcggta agttttccga agtaaccgga aaatctgcat taatgcaaac tcggcgacac
     8701 tccgcggtga atatgctggt acattggtta cgactaagcc attttcgtta gcctttttga
     8761 tgtcgaccat gtcaaatccc gcggtccgag tagcaatttg tttcagacca ttggcatgta
     8821 gcttttcata aatatcagcc ggaactttac tgcgttgctg aatcacgagt ccatcaacat
     8881 cggccgttaa ttcaacagca tcgtcaatta atttcggcgt tgtgatgatt tcgatattat
     8941 gttctttcgc gtattcgtta atggcggttt gttcatcgtc ccgcacacta gtcatcaaga
     9001 ttttcgtcat gctaatcctc cttattaatg aaggccgcaa tgttatcaag agctccggtt
     9061 agattttcca tactggtggc gtaactaatt cgaacatatc cttggccgcc agctccaaag
     9121 aaggaaccgg gaatcacagc aacttttcct tcattagcaa gatctgtcgc aaatttaagg
     9181 tcatcattac catattgttc aggaatctta gcaaaaacgt agaaggctcc ttgaggatta
     9241 atcagctcga atcctaattt ttggaggcta tcaacaacaa agtctcgtcg ttgctcatag
     9301 gcatctttca tttcttgagt agctgctttt ccttcgtcag taccaaatgc ggctactgca
     9361 gcggccattg ctggattaga agcagcggtt actaacatcg cgtgaatggc actgaccgat
     9421 ttcatcaatt cttgcggccc agcgataaaa ccaattcggt aaccagtcat tgcatgtgat
     9481 tttgaggcac catttaaaat tagcgtttgt tcggggatgt aattagcgat tgaagtatga
     9541 gtagctccgt aaaccagttc agagtaaatt tcatctgcaa ttacaatcag gttagttgat
     9601 ttaatcgtat cggctagtgc tttaatttga tcttgggtgt aagtaacacc agttgggttg
     9661 gaggggtagt taagaactag tccctttgca ttaggatgtt cttctagtac gctttggagt
     9721 cttgcgggtg tgagaacaaa atcatcgccg cttgtatcaa cttcaatcgg aatcccacca
     9781 agaatctttg taacagccat gtagaagggg aaagttgggg ttggaatgat aatttcgtcg
     9841 ccgggattaa taatagtaga aagagaagcg aaaattcctt ctgttgcgcc aactgtaaca
     9901 gcaatttcgt tttttggatc gtattccagt ttgtaacgat cttgcatgaa gtgagcgatt
     9961 gcttgacgaa gtgcgaaagt cccatttccc ggagcatagt gtgaatcatt ggcattgatg
    10021 ctatcgattg cggcctgctt cattgcggct ggcacattaa agtctggttc acctaatgtt
    10081 agtttaatga tgccagggat tgcgctgact tgatagtcaa attcgcggat cccaccagga
    10141 gtgagtttag cgaaattatt gttaagacga ttgagaattt cttttttagt agttggcatg
    10201 ataaattcct cctatataat atgtagattt agaaaaaaga agccctgaat gctataggaa
    10261 aaacatccag ggcttcttga tcagattgga atgagtataa aagaggctct cggatgtttg
    10321 ggggtcatcc gggaacatca caatgataaa atcactgctg gttagcggac ggtaatcgcg
    10381 ctaaaccaga agacatacgc ttgattcaag tgaattgtcg cagtgctcat cattgtgtcc
    10441 tccttttgat taactgatta ttaattattc taattatttt ttaatctttg tcaagggttg
    10501 attaagaaaa aatattaatt acaaaattat ttattgatga caaatgtaaa tataatgaaa
    10561 tgcgaaaatg tttgtgatta ttagttcgcc tttaatttaa tattaaattt atattctaca
    10621 atttttttta ttttttcgtg tcttttttgt tgtcttactc cacaaatgtg atataatatt
    10681 aatcgtaaag gaagtgggta gcaatgcgga tcgacatcaa acattatttg gaagttaacc
    10741 acttgaccat ttatcaagtt tccaagcgtt ccggttacgg ctacacgact ttacacaaat
    10801 cgtttaacaa accacagtct agttcgacct cgcttaacct gcgtgatctt gatgccttgg
    10861 ctcgtgctca ggacaagagt atgtgggagg tccttaaaga actagaagag cattacctcg
    10921 aatgagattg tggctttgct gtagccacag gaagttaaat gcgttaactt ttaacttcta
    10981 gaatacttag actacgaaac ttagaaaaca aaatattata tttaattgag gagggattgc
    11041 atatggctca aaacccaatg aatccatttg acaacgacat gaatgacatc tttaatcaat
    11101 taatgggtgg catgaatggt ttcaattctg ataatcggcg ttacctaatc aatggtcgtg
    11161 aagtaacacc agaagaattt gctgaatatc gtagaactgg tcaattgcca ggcggtgcaa
    11221 atcctcaaca aggtgggcaa cctggccctc aacctaacgc aggtaaggac agtatcttac
    11281 acaagttagg tcgaaactta actcaagaag ctcgtgaaca tgaacttgac cctgttattg
    11341 gtcggaacaa ggaaatccaa gaaacagctg aaattttaag ccggcgcaca aagaacaacc
    11401 ctgtattagt tggggatgct ggtgttggta agactgctgt tgttgaaggt ttagcacaag
    11461 caattgtttc cggcgatgta ccagctgcta tcaaggacaa ggaaattatc agtatcgata
    11521 tttctggcct tgaagcaggt actcaatatc gtggtagttt tgaagaaaac atgcaaaagt
    11581 tggttgatga agtcaagaag gctggaaata tcatcctctt cttcgatgaa attcaccaaa
    11641 ttatcggtgc cggttcaact ggtgattcta gtggttctaa gggtatgtct gacattatta
    11701 agccagcatt atcccgtggt gaactaacgg ttatcggtgc aactactcaa gatgaatatc
    11761 ggaacactat tatgaaggat gctgcattag cacggcggtt caattctgtt actgttaatg
    11821 ctccaagcaa ggctgataca gtggccatcc ttaaaggtat ccgtgacttg tacgaacgtc
    11881 accacaatgt aaagttacca gatgacgttc tccaagctgc tgttgattac tctgttcaat
    11941 acatgccaca acgtgcatta cctgacaagg ctatcgactt aatcgatatg accgctgctc
    12001 acttagcagc aaagcaccca gcacgtgatg ctaaggcaat tgaaaaagat atcgaagcag
    12061 aagaaaagaa gcaaaaagcg gctgctaaga aagaagatta caaggctgcc caagatgcaa
    12121 aggaaaagat tgctgacttg aagaagcaat t
//
