LOCUS       c00047_JAJGUR0..       12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGUR010000086.1 Limosilactobacillus reuteri strain LTM_Jesus_5_1
            scaffold86, whole genome shotgun sequence.
ACCESSION   JAJGUR010000086
VERSION     JAJGUR010000086
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 15:40:27
            Original ID  :: JAJGUR010000086.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 68437
            Orig. end    :: 80588
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[73437:75588](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7151)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1098..1319)
                     /locus_tag="ctg47_44"
                     /transl_table=11
                     /translation="MRIDIKHYLEVNHLTIYQVSKRSGYGYTTLHKSFNKPQSSSTSLN
                     LRDLDALARAQDKSMWEVLKELEEHYLE"
     CDS             1824..3011
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value: 4e-71.
                     Score: 231.8. Matches aSDomain:
                     nrpspksdomains_ctg47_45_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 269.1; E-value: 1e-81)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_45"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4e-07, bitscore:
                     22.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFAKLTPGGIREFDYQVSAIPGIIKLTLGEP
                     DFNVPAAMKQAAIDSINANDSHYAPGNGTFALRQAIAHFMQDRYKLEYDPKNEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSGDDFVLTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTIKSTNLIVIADEIYSELVYGAIHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKAATQEMKDAYEQRRDFVVNSLQKLGFELINPQGAFYVFAKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNITAFINKED"
     aSDomain        1932..2984
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg47_45_Aminotran_1_2.1"
                     /evalue="4.00E-71"
                     /label="ctg47_45_Aminotran_1_2.1"
                     /locus_tag="ctg47_45"
                     /protein_end="387"
                     /protein_start="36"
                     /score="231.8"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPAAMKQAAIDSINANDSHYAPGNGTFALRQAI
                     AHFMQDRYKLEYDPKNEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSGDDFVLTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTI
                     KSTNLIVIADEIYSELVYGAIHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKAATQEMKDAYEQRRDFVVNSLQKLGF
                     ELINPQGAFYVFAKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             3013..4008
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 295.4; E-value: 6e-90)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_46"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELAADV
                     DGLVIQQRSKVPADIYEKLHANGLKQIATRTAGFDMVDIKKANENGLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSIEIHTARIGIIGVGRIGGTLAKL
                     LNALGATVLGYDTNPRTDLDGIVQFVSKEKLLKQADVVSLHVDLNPTSKGLLTANDFAM
                     MKPTAGLVNASRGPVVNTADLVTALKAGEIAAAALDTFEGEETVAAADRREKGLDDQPL
                     VKELHEMDNVIITPHIAFFTNLAVKNMVDISLDDVMTILNSEKSPHEITL"
     CDS             4076..4504
                     /locus_tag="ctg47_47"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             4783..4968
                     /locus_tag="ctg47_48"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYIYLLLLFLWIAPFSDGSLPLDESLLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(5001..7151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 325; E-value: 1.5e-98)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_49"
                     /sec_met_domain="TIGR01193 (E-value: 1.9e-276, bitscore:
                     911.5, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.2e-40, bitscore:
                     128.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYPYYVAQVDETDCGVAALAMILRNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFDRLWSGVCLLFSPAKGYTPQKEPLAGLTTMFQQLTNY
                     KKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLAILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGMMVIIGIVLSLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAILVIQDRLSIGTLMAFNALLAFFISPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDTEKSDTNSQDQTDLIGPINIQHVDYSYEYSRPILKDINLQIGCNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQSPQLFSGTIKDNL
                     LMGLDHEISAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALL
                     TSAHVLIFDESTSSLDPITEKRIVENLLEIEDRTMIFIAHRLSIAKKVNKVVVMCDGKI
                     IEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7230..7415)
                     /locus_tag="ctg47_50"
                     /transl_table=11
                     /translation="MVKVRINKQFYKDFNFYFYMLFIVLWIKPLIDAENGYEFTYCLVF
                     LVGAIIATLLTIFKTK"
     CDS             complement(7428..7589)
                     /locus_tag="ctg47_51"
                     /transl_table=11
                     /translation="MAYRKLNFNELSDVSGGWGVTPWNLVEPVGRVAGSLWKHRRSYYA
                     GYRDSPFH"
     CDS             complement(7591..7758)
                     /locus_tag="ctg47_52"
                     /transl_table=11
                     /translation="MIKILNNTELREINGGFKHNIWYYYGWGRASCIGTQRRNPSAFLN
                     HPNFIVLGGN"
     CDS             8024..8179
                     /locus_tag="ctg47_53"
                     /transl_table=11
                     /translation="MVKPLDDKFLAKVTGGYGYGNFVASAIYSVAKSAWHHRRDIGQGY
                     LDSPFH"
     CDS             8391..8561
                     /locus_tag="ctg47_54"
                     /transl_table=11
                     /translation="MTTKKLKSSELEKIIGGRSWVGKGWYYTSYGWASGIAAKKRFPGA
                     FLNNAFFVTSK"
     CDS             complement(8660..9433)
                     /locus_tag="ctg47_55"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYIENIVTQRRMINNTLQSYDMKVWLQTNDP
                     QEVIKKVKNEDYFAILDIELDGDISGIDVAEQIRAKSEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGDKIESITDRLRIDIDEAYVRYQNYVNNNQHHQDKFIYEPIRGVKRQVDF
                     EDLYYIEAIKNKSRRLRIVGKSIRIEYHGELGKISDERLLRINQSTLINPLSIQRFSKK
                     ERTVYFDDEISVTVSYRKLKLLTDFLNDMKNNMVY"
     CDS             complement(9441..10754)
                     /locus_tag="ctg47_56"
                     /transl_table=11
                     /translation="MIHLTVGQGLTSSILNIIEIIFIYQLVTSDFSLGLVIIDFLAVLM
                     IIFFSIVFFMLGSLYPVLIVFYFWLVDRIKSNSYIVINSILAMCISIVMASLFDLVDHY
                     TYTFFLQGKTDIALLGWLIPINDLIITIVVAILAIKVVRPKLRWIRINFPRPIGLWQIT
                     AILFMLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCATGFINFVKSSQQTQRQQQII
                     DKYQAQIANANQLNQQYNEIRRERHDTRNMLLSVQGYIRDHKDKEAEKLLATFLQNDTV
                     EKHYGEIDNALDKIKISGLHNLIKEKAYKIVEKGIPFSFEVNAEIDELPGSEIKTARII
                     GILMDNAIEATFKQTKPYIQFALLKHSPEVYELVIANSIEQKLNINTALKFEHSTKEGH
                     QGIGLSNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             complement(10909..11073)
                     /locus_tag="ctg47_57"
                     /transl_table=11
                     /translation="MVDLNLETKKNLVIINLFYIGLIALYCILHAGPLNFLVFLGMLVL
                     ANIAEFVVK"
ORIGIN
        1 gctgggtgct ttgctgctaa gtgagcagcg gtcatatcga ttaagtcgat agccttgtca
       61 ggtaatgcgc gttgtggcat gtattgaaca gagtaatcaa cagcagcttg gagaacgtca
      121 tctggtaact ttacattgtg gtgacgttcg tacaagtcac ggataccttt aaggatggcc
      181 actgtatcag ccttgcttgg agcattaaca gtaacagaat tgaaccgccg tgctaatgca
      241 gcatccttca taatagtgtt ccggtattca tcttgagtag ttgcaccgat aaccgttagt
      301 tcaccacggg ataatgctgg cttaataatg tcagacatac ccttggaacc actagaatca
      361 ccagttgaac cggcaccaat aatttggtga atttcatcga agaagaggat gatatttcca
      421 gccttcttga cttcatcaac caacttttgc atgttttctt caaaactacc acgatattga
      481 gtacctgctt caaggccaga aatatcgata ctgataattt ccttgtcctt gatagcagct
      541 ggtacatcgc cggaaacaat tgcttgtgct aaaccttcaa caacagcagt cttaccaaca
      601 ccagcatccc caactaatac agggttgttc tttgtccgcc ggcttaaaat ttcagctgtt
      661 tcttggattt ccttgttccg accaataaca gggtcaagtt catgttcacg agcttcttga
      721 gttaagtttc gacctaactt gtgtaagata ctatccttac ctgcgttagg ttgagggcca
      781 ggttgcccac cttgttgagg atttgcaccg cctggcaatt gaccagttct acgatattca
      841 gcaaattctt ctggtgttac ttcacgacca ttgattaggt aacgccgatt atcagaattg
      901 aaaccattca tgccacccat taattgatta aagatgtcat tcatgtcgtt gtcaaatgga
      961 ttcattgggt tttgagccat atgcaatccc tcctcaatta aatataatat tttattttct
     1021 aagtttcgta gtctaagtat tctagaagtt aaaagttaac gcatttaact tcctgtggct
     1081 acagcaaagc cacaatctca ttcgaggtaa tgctcttcta gttctttaag gacctcccac
     1141 atactcttgt cctgagcacg agccaaggca tcaagatcac gcaggttaag cgaggtcgaa
     1201 ctagactgtg gtttgttaaa cgatttgtgt aaagtcgtgt agccgtaacc ggaacgcttg
     1261 gaaacttgat aaatggtcaa gtggttaact tccaaataat gtttgatgtc gatccgcatt
     1321 gctacccact tcctttacga ttaatattat atcacatttg tggagtaaga caacaaaaaa
     1381 gacacaaaaa aataaaaaaa attgtagaat ataaatttca tattaaatta aaggcgaact
     1441 aataatcaca aacattttcg catttcatta tatttacatt tgtcatcaat aaataatttt
     1501 gtaattaata ttttttctta atcaaccctt gacaaagatt aaaaaacaat tagaataatt
     1561 aataatcagt taatcaaaag gaggacacaa tgatgagcac tgcgacaatt cacttgaatc
     1621 aagcgtatgt cttctggttt agcgcgatta ccgtccgcta accagcagtg attttatcat
     1681 tgtgatgttc ccggatgacc cccaaacatc cgagagcctc ttttatactc attccaatct
     1741 gatcaagaag ccctggatgt ttttcctata gcattcaggg cttctttttt ctaaatctac
     1801 atattatata ggaggaattt atcatgccaa ctactaaaaa agaaattctc aatcgtctta
     1861 acaataattt cgctaaactc actcctggtg ggatccgcga atttgactat caagtcagcg
     1921 caatccccgg catcattaaa ctaacattag gtgaaccaga ctttaatgtg ccagccgcaa
     1981 tgaagcaggc cgcaatcgat agcatcaatg ccaatgattc acactatgct ccgggaaatg
     2041 ggactttcgc acttcgtcaa gcaatcgctc acttcatgca agatcgttac aaactggaat
     2101 acgatccaaa aaacgaaatt gctgttacag ttggcgcaac agaaggaatt ttcgcttctc
     2161 tttctactat tattaatccc ggcgacgaaa ttatcattcc aaccccaact ttccccttct
     2221 acatggctgt tacaaagatt cttggtggga ttccgattga agttgataca agcggcgatg
     2281 attttgttct cacacccgca agactccaaa gcgtactaga agaacatcct aatgcaaagg
     2341 gactagttct taactacccc tccaacccaa ctggtgttac ttacacccaa gatcaaatta
     2401 aagcactagc cgatacgatt aaatcaacta acctgattgt aattgcagat gaaatttact
     2461 ctgaacttgt ttacggagct attcatactt caatcgctaa ttacatcccc gaacaaacgc
     2521 taattttaaa tggtgcctca aaatcacacg caatgactgg ttaccgcatt ggttttatcg
     2581 ctgggccgca agaattgatg aaatcggtca gtgccattca cgcaatgtta gtaaccgctg
     2641 cttctaatcc agcaatggcc gctgcagtag ccgcatttgg tactgacgaa ggaaaagcag
     2701 ctactcaaga aatgaaagat gcctatgagc aacgacgaga ctttgttgtt aatagcctcc
     2761 aaaaattagg attcgagttg attaatcctc aaggagcctt ctacgttttt gccaagattc
     2821 ctgaacaata tggtaacgat gaccttaaat ttgcgacaga tcttgctaat gaaggaaaag
     2881 ttgctgtgat tcctggttcc ttctttggag ctggcggcca aggatatgtt cgaattagtt
     2941 acgccaccag tatggaaaat ctaaccggag ctcttgataa cattacggcc ttcattaata
     3001 aggaggatta gcatgacgaa aatcttgatg actagtgtgc gggacgatga acaaaccgcc
     3061 attaacgaat acgcgaaaga acataatatc gaaatcatca caacgccgaa attgattgac
     3121 gatgctgttg aattagcggc cgatgttgat ggactcgtga ttcagcaacg cagtaaagtt
     3181 ccggctgata tttatgaaaa gctacatgcc aatggtctga aacaaattgc tactcggacc
     3241 gcgggatttg acatggtcga catcaaaaag gctaacgaaa atggcttagt cgtaaccaat
     3301 gtaccagcat attcaccgcg gagtgtcgcc gagttcgcat taatgcagat tttccggtta
     3361 cttcggaaaa cttaccgctt tgaccaccaa gtcgccgaaa atgacttccg ctggtttagc
     3421 gatgaacagt caatcgaaat tcacacggca aggattggaa ttattggggt cgggcgtatc
     3481 ggcggaacac ttgctaaact tctcaatgcc ctcggtgcca ctgttcttgg ttatgacacg
     3541 aatccgcgca ctgacctcga tggaattgtc cagttcgttt ctaaagaaaa attactaaag
     3601 caagccgatg ttgttagtct ccacgttgat ctaaacccaa cttctaaagg tttgctgacc
     3661 gctaacgact ttgcaatgat gaaaccaact gctggtttgg tcaatgctag tcgtggtcca
     3721 gtcgttaata cagctgacct cgtcacagca ttaaaagctg gtgaaatcgc cgcggccgcc
     3781 cttgatacct ttgaaggtga agaaacagtt gcagctgcgg accgccgaga aaaaggcctt
     3841 gatgatcagc cccttgttaa agaattacat gaaatggata atgtcattat tactccccac
     3901 attgctttct ttactaattt agcagtcaaa aacatggtgg atatttcact tgatgatgtg
     3961 atgacaatcc ttaatagcga aaaatcacca catgaaatta ccttataatt gagcaccctc
     4021 attgaccaaa agtatcgtct cgattacact atgggtatta aaggagggaa cggttatgag
     4081 taaatataaa gtaactgcaa ctaagacaac aacggggatg caggtttcag caggtacccg
     4141 tggttttgaa attacctttg atgagccaga aagtactaat acggggatga atccagtaga
     4201 aattcttctt gcgtcatttg gtgcctgtca ggcaatcact gcccaagcat tagctaaaaa
     4261 gcgtaacttt gacttacgag ctttttgggt aacaatcgag ggtgatcttg gtcgtgaaga
     4321 cgttgctgat ggcaagaatg ttcgtaagtt tactgagatc cgttaccaac cacaccttcg
     4381 cagcagcgag tctgatgaag acatcaagaa gttcctcgct gacgttgccg caaagtgtcc
     4441 tgtggaaaac accctgacct acggaacgaa atttgttcaa gatggatttg taaaagttga
     4501 ttagttgaaa agggagcgag atagaagtca ctcgtgactt cgttttcgag cccccgcaag
     4561 caacaatagg cctccaacat tcggttttac cgagcgttgg aggccattgg tgtactgcgc
     4621 catttgtttt tttatgaaag taacttcgct tatgtcacag tccctttcta aataggcagc
     4681 ctatacgaat tctgcaagaa acttaacgaa ttttgcaaag tgtcctttaa attagatctt
     4741 tcattataat aaggtacaca tactgtctta gggggagaac taatgaaaat tcatttcaat
     4801 aaggactttt ggcgggatgg tttcttttat atatacttat tacttttgtt tctctggatt
     4861 gctccatttt cagatggttc gctgccatta gatgagtcac tactatgtat cttctttata
     4921 atttttacta tcggttcgat gctcgcaatt atgtttaata aagactgaaa aaaggctcca
     4981 acagcaatgt tcggagcctt ttatgcattc cacaaattat agtattcttg atgatgattc
     5041 aaaagttctt ggtgagtacc ctgttcaatg atttttccgt cgcacattac taccacttta
     5101 ttgactttct tagcaatcga aagacggtgg gcaataaaaa tcattgtgcg gtcttcaatt
     5161 tcaagcaaat tctcaacgat tcttttttca gtaattggat ctaaactact tgttgattca
     5221 tcgaaaatta aaacatgcgc agaagttagg agtgctcgtg caatcgtcaa gcgttgtttt
     5281 tgaccaccag ataatgcggt tgcttcttca tctagttttg tttcatattt taagggcatc
     5341 tcttgaatat cattatagat taatgccaat ttacatgcat tatcgatttc ttctgcggat
     5401 atttcatgat ctaatcccat taacaagtta tctttgattg ttcccgaaaa taattgtggc
     5461 gattgaggta agtaatgtac atattgtcta atatcgcaaa gattaatctc tgttgtctta
     5521 tgctgattaa attctatctg cccttgagta ggtaaataaa agccaactaa cagctttgcc
     5581 aaggtcgatt taccagaacc gctcaaccct acaattgcca atttgtcatt acaaccaatt
     5641 tgaagattga tatcttttaa aattggacga ctatattcat atgaatagtc aacatgttga
     5701 atgtttatcg gccctattaa atctgtttga tcctgagaat tcgtatctga cttttcggta
     5761 tcaacttgca gcacttcatt caatcgatta ttcgctactt tagcttcttg gagtttaggt
     5821 tgaagattaa taatattttg caacggactg ataaaaaagg ctaataatgc attaaaggcc
     5881 attaatgtcc caatacttaa tcggtcctga attaccaaaa ttgctccttg aaaaagaatg
     5941 attgttacta aaccgtattg aatccacatt ttaattgcat cctgaaaaga tttagtttta
     6001 acatatgtta gattctttcg taagaaatcc gcaaattgct tttcaacatt tttataacgg
     6061 atattttcaa gttgcagcac tttcaacgtc tctacgcctt ttaaatcctc aataattgca
     6121 gaacttaatt gagcattact ctccatctgt tcctgatcaa gtttagcaaa gcgcttatta
     6181 aaggcataaa tgataataac ataaatcgga atggtactaa ttgtagttaa aaataatgac
     6241 cgatcatata aagaaagaac aattcctata atcaccatca tgccaacgtc taagaacatt
     6301 gaaataatag tgcttgataa ggcatcaata atcttattaa tgtcattaaa ccgtgaagta
     6361 atttctcccg tttttcttgt ggagaaaaat cgcatcggta gacgataaac atggtgaata
     6421 tatctaagac ttatttgtga tgtcagtttt tgatccagcc tagtcaaaag aacatctcgc
     6481 agataattaa aaagagaatt aaacacataa actactaata aactaccagc gaggatcgct
     6541 aagccattaa tatttttcga gggaataaac cgatcaataa ttaattggag atagtatgaa
     6601 ccgacgatgc tgatgaaagt aattagcatt gccgcaataa caattccgga tatatctttt
     6661 ttataattag ttaattgttg aaacatcgtc gttaatccag ctaaaggttc tttttgcggt
     6721 gtatacccct tagcaggcga aaaaagcaaa catacacctg accataaacg atcaaattca
     6781 tcccgcgtca ttttttgtac tttcgtagca ggatctggat cagctacata gatgtaatct
     6841 tgatcagcct taaaaacgac acagtaatga agtaaatcat ccttaatcac atgtgcgatc
     6901 aatgggtaag taatttcagg atcatcaaac aatgatatat ctgcttgaat gggtataacg
     6961 tctaatccaa gatgcttcgc tgcttttaca agtcctaagg cagtagttcc ttgcttagtc
     7021 gtccgggcta ggtcacgtaa ttttgcgatt ggataaacag agccaaaatt gcgcaaaatc
     7081 atcgctaaag cggcgactcc acaatctgtt tcatcaactt gggctacata ataaggataa
     7141 ttgattttca ttcaccttgc tttctaatta gacaaagaaa taaagtccaa aattaataat
     7201 gattctgggc tttatattct tataagatac tatttagttt taaatatggt taataaagta
     7261 gcaattattg ctccaactaa gaaaactaag cagtaagtaa attcataacc attttctgca
     7321 tctattaacg gtttaatcca aagaacaata aataacatgt aaaaataaaa attaaaatct
     7381 ttgtaaaatt gtttattaat tctcactttt accatcttct cctcttatta gtgaaatgga
     7441 ctatcccgat aaccagcgta ataagagcga cgatgcttcc aaagtgaccc tgccactctg
     7501 ccaacaggtt ctactaaatt ccaaggagta actccccatc caccagaaac atcgcttaat
     7561 tcattaaagt tcaatttacg gtaagccatt ttaattacct cccaatacga tgaagttagg
     7621 atgatttaag aatgcactag gatttcgacg ttgtgttcca atgcacgatg ctcttcccca
     7681 accatagtag taccaaatat tatgcttaaa tccaccatta atttccctaa gttcagtgtt
     7741 attaagaatt ttaatcataa ttactcctcc tcgtaattat taattttagt aaatcaggtt
     7801 attactttcc ttaattacac tattagtata tatgtaaaaa ttttcttcgt atcattttgc
     7861 aagattcgtc caatctcccg cataatttgt aaccaatcca agaaaatcta acgaattatg
     7921 cactaactca aacgaatact gcaaaattgt aaaaacgctt acaaagattt tataataatc
     7981 ataacagagg aggaaaaatt aattacaact ggaggaattc aaaatggtta aaccacttga
     8041 tgacaaattt ttagcaaaag ttacaggagg atatggctat ggtaattttg tagcctcagc
     8101 tatttattct gttgccaaaa gtgcatggca tcaccgtcgt gatattggac aaggttatct
     8161 cgattcaccc ttccattaaa agaagtgata ctaatggcat ataaactcaa tagaaaatat
     8221 tacaaaagtc taaactttta ttttggtata gtcgctctta tactttggat tttttctgtt
     8281 ctcaatccgc tttcttttat tgatttttta attagcgctg cctttttaat ctattcaatc
     8341 tatgccttat gtaaaagttt aattattaag aaataaggga agttatttta atgacaacaa
     8401 aaaaactaaa gtcttcagaa cttgaaaaaa tcattggtgg cagatcttgg gttggtaaag
     8461 gatggtatta tacttcctac ggctgggcta gtggtatagc tgcaaagaaa agatttcctg
     8521 gtgcttttct taacaatgca tttttcgtaa caagtaaata aatactatga atgctcctct
     8581 gtatctaatc aaaaagttaa tttatacaaa agaaccagat cctattcagg atctggttct
     8641 tttgtttgat tctcacgtgt caataaacca tgttattttt catatcatta agaaagtcag
     8701 tcagtaactt caatttccga taacttactg tcacacttat ttcgtcatca aagtatacag
     8761 ttctctcttt cttgctaaac ctttgaattg ataaaggatt tatcaaggta ctttggttta
     8821 ttcgtaagag tctttcatct gagatcttgc ctaattcgcc atgatattca atccgaatac
     8881 tttttcccac aatccttaat cgccggctct tattttttat tgcttcaata taatataagt
     8941 cttcaaaatc aacttggcgt ttcacgcctc gaattggttc gtaaataaat ttatcttgat
     9001 gatgttgatt attattcaca taattttgat agcgaacata tgcttcatca atatctattc
     9061 gaagtcggtc agtaatggat tcgattttat cacctttaga tatataatca aaaggctcta
     9121 ttcggcgcga aacagtataa ggtaaatatt cttgataagc agttacaaag ataatttccg
     9181 caaattctga ctttgcacga atctgttcag caacgtcgat tccactaata tctccgtcca
     9241 attcgatatc taaaattgca aaataatcct cattttttac tttttttatt acttcttgag
     9301 ggtcatttgt ttgcaaccat actttcatgt cataactttg aagagtatta ttaatcatcc
     9361 gtcgttgagt gactatattt tcaatataat cagcttgata atcatcattt tctagaataa
     9421 ttacctttaa cattttattc tcactttccc tgaataaaac aagtcatcat aattacctta
     9481 tctttaactt ccgctgaaaa agaataatgg tcatcatttt ctaccaactg tgtcacattt
     9541 gaaaggccaa ttccttgatg cccttcttta gtcgaatgtt caaattttag tgcagtatta
     9601 atattaagtt tttgctcaat cgaattagca attaccaatt cataaacttc tgggctgtgc
     9661 ttaagcaatg caaactggat ataaggttta gtttgcttaa aagttgcttc aattgcatta
     9721 tccattaaaa taccgataat tctagcagtt tttatttctg aacccggcaa ctcgtcaatc
     9781 tcagcattaa cttcaaacga aaatggaata cctttttcta ctattttata agccttttcc
     9841 ttaataagat tatgcaaccc tgaaatttta atcttatcta atgcattatc aatttcacca
     9901 taatgctttt caactgtatc attttgaaga aacgttgcta gtaatttctc cgcttcctta
     9961 tctttgtgat cacgaatgta tccttgaaca ctgagaagca tattgcgtgt atcgtgacgt
    10021 tcacgccgaa tctcattgta ttgttggttc aattgattgg cgttggcaat ctgtgcttgg
    10081 tatttatcaa tgatttgttg ctgtcgttgc gtttgctgac tacttttaac gaaattaata
    10141 aatccggttg cacatactac gataattatc aaatacatta ttaacaacag cgaggcatac
    10201 ttatttgcta ccccgtcctt ttcggcaata gcagttaacc acacataaag catgaacaaa
    10261 attgctgtaa tttgccataa ccctatcggt cgaggaaaat taatcctaat ccatctcagt
    10321 ttgggacgaa ctactttaat tgctaagatt gcaactacaa tagttatgat taaatcatta
    10381 attggaataa gccatcctaa aagtgctata tctgtctttc cttgtaaaaa aaacgtataa
    10441 gtatagtgat ctactaaatc gaataaagat gccattacaa tactaataca catcgcaaga
    10501 atactattta taactatata agaattagat tttattctgt caactaacca aaaataaaat
    10561 actataagta ctgggtatag cgatcctaac ataaaaaata ctattgagaa aaatataatc
    10621 atcaagacag ctaaaaaatc aattattact aatcctaatg aaaagtcgct agttaccaat
    10681 tgatatataa atattatttc aataatattt aatatagatg acgttaatcc ttgtcctaca
    10741 gttaaatgaa tcatctttta atccaattta aaactgctct ttcccatgaa cgaggacttt
    10801 taaaggcaag tgaatacccc caaccaccta atactttaga taattctttc cttgataaaa
    10861 atttatatga tttttttaac ataattacct ccaataaata acaattacct atttaactac
    10921 aaattcagca atattagcca aaactaacat tcccaaaaac actaaaaaat tcagtggccc
    10981 tgcatgcaaa atacaataca aggcaatcaa tccgatataa aaaaggttaa tgattaccaa
    11041 atttttcttc gtttctaaat tcaaatccac catataacta actcctactt tatccatccc
    11101 tcagacaagg cgaatgaaat aataattgtt aatatgaaac aaacaaccgc aatcattatt
    11161 gagcgttcag cacttgggcg cataataaat tctcctttag tagataatta caggctcatt
    11221 tttctgtaag tcatgaaagg cttgagcagc aacatctgga tgcatgttaa tacaaccgtg
    11281 cgatccaccg cctttagcaa gataagcctg ttttgaccaa tcgtggcgcc agcttgcatc
    11341 atgaaatcca cagccactat cagtaaatgg tgaccaatat tggaccttac ttgcatattt
    11401 tgaaccatca tcgttaaggc ctcgaagaac agacggtgtt tgctggtaca tgatatacca
    11461 gacaccctta ggagtttcat tatccttatt attcgttcca ctaacaatat cagtactaag
    11521 aacacattta ccattcttat agaaccacgc atgttggtcg gctagtgaaa cttcggcgta
    11581 agtgtcccct atgccgttgt tacttgtggt attataccca gttccttgtt gattataacc
    11641 tttaccatag atatcatttt tggcgtttac tgtttgctta tttgcaacca atgcattcgt
    11701 aagagtcttt ccagcttgtt tcttactgat cttccaacca tatgaaccag catctgttgt
    11761 tttgatcact gatccatcat gtgttttgaa ttcaaatgat ttgccaagag ttgcttgggt
    11821 attattaatt tcatcaatct ttgaattagc tgctccagtg tcaaagtgat attttccatt
    11881 ttgatatgtt gctctggtaa taatctcacc acaatttaat tgatactttt tgttttgtac
    11941 ttggtatgtt acagatcgtt ttgataattc ttcgagcttt gctttttcat tttgaacagt
    12001 tttactattt gcagaaagcg gagctttgta tactggcctc aagtaaatag ttccgccagc
    12061 aatctcattc tcaactttat tatgcaagcc atctaaactg tattgagtac caccaactgc
    12121 tggttttact tgtactcggc cattttcgta t
//
