LOCUS       c00002_JAJGUW0..       14605 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGUW010000101.1 Limosilactobacillus reuteri strain
            BHM_Lincecum_1_1 scaffold101, whole genome shotgun sequence.
ACCESSION   JAJGUW010000101
VERSION     JAJGUW010000101
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 15:46:54
            Original ID  :: JAJGUW010000101.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14605
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14605
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4440:9605]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4441..9605
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14605
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14605
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(4..1386)
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="VRQSQKTGQQADRLPRIGLENRKYTRARSTDYGEGKGMSVTIQDL
                     VLDRNNLNQAYLRVKRNKGAAGIDGMTVNDLLPYLRENKTELIASLREGKYKPAPVKRV
                     EIPKPNGGVRKLGIPTVVDRMVQQAVAQILTPIFERVFSDNSFGFRPHRGAHDAIAKVV
                     DLYNQGYRRVVDLDLKAYFDNVNHDLMIKYLQQYIDDPWTLRLIRKFLTSGVLDHELFA
                     RSEKGTPQGGPLSPLLANIYLNELDKELTRRGHHFVRYADDCNIYVKSQRAGERVMRSI
                     TRFLEKQLKVKVNPDKTKVGSPLRLKFLGFSLGVDHNGAYARPAKQSQQRVRKALKLLT
                     KRNRGISLTRMFEEIHRKMRGWLQYYSIGKLTDFIQRLDKWLRARIRQYIWKQWKKFKT
                     KVTNLQKLGLSQHDAYVFASTRKGYWRTAHSKTLSYSLTNRKLEQLGLMNMSKTLQSIQ
                     CD"
     CDS             2122..2271
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MIKMPVCKMDSVRYLIRTGKQGALIGILFYYKRMIKEISYSKKLI
                     SSNR"
     CDS             complement(2462..2788)
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MSFTMNLYYTGEGDNAKKFAQEMEERGIADKIRQQPGNLKYEYFQ
                     PLDDPHTILLIDTWESQEALDADHNSPMMAELAKLREKYNLHMRAERFVPENLPDKDNK
                     FLRK"
     CDS             complement(2809..3303)
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MTLGTYQQVKDALKNFGITDYTVIDHPAAHTTEEADAYIAGHEGV
                     RTKTMFLKGKKKNFYMVIMDDKKPMDFHKFMALTGAKRVSMARPEYLQEQLGLAPGIVS
                     PFGLLNNEAHNVKVYFDKDIVNEPIQTFHPNENTHTIFIKTDDLFKFLKQVDFEPEIID
                     L"
     CDS             3547..3807
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MSSKVQVNIDPELKQSAENIIKEIGLTPTAVINGMYKQIVATGKI
                     PLSFSLTSRQRAELELREVSKKIPVREVKTKEEFEEFFNED"
     CDS             3797..4123
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MRTNQIYTAYVSWGLDGKRRPVLIVEDKNKNVFCYRITSKYKNKS
                     ERIKKNYFPLMDWKIEGLDKQSYIDVGDIIKLSKEHVSFRLVGELSIRDIEALVEFIRN
                     RYEI"
     CDS             complement(4441..6600)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 280.8; E-value:
                     3.7e-85)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_7"
                     /sec_met_domain="TIGR01193 (E-value: 3.1e-289, bitscore:
                     952.6, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.4e-39, bitscore:
                     124.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYNFRRHYINQVDEADCGVAALAMILHNYGSKISLATLRKFTKTT
                     TDGTTALGIVKAAEKLKMDVEAYQADASLFDSKDVIYPFIAHLIKKDSGLLHYCVVFKS
                     SKKHIFIADPDPNIQVKRIPKVNFFEEWTGIAIFAKPGKNYKAIQEKIPTFKRLCRPLF
                     QQKSLLFGIITAAFIVTFLNILNSYYLQTLLDTLIPNKLQDPLAIISIGLLFAYLFNSL
                     FTFSRDYLLAILGQKLSKIIILNYIKHVLRLPMAFFSTRKTGDILSRFTDANKVIDALV
                     SAIISIFLDATILIIIGTVLALQDIRLFGITMLIIPIYSLIIFSFTSNFRKLNQKEMES
                     NATVSASIIEDIRGIETIKSLNCEEVRSDKITNEFNDFLHKSLVHTRLNNIQQGLKTFV
                     QLSLNLIILWVGANQVIKNELSIGQLMTYNALLVYFTTSLQNIINLQPKIQSAQVANNR
                     LNEIYMVKDEFKNTTKHNHSLKNGTIELKNVSYSYEYNSPILQNINLKIKSGEKLTIVG
                     LSGSGKSTLMKLLVNYFDVSNGEILINNLNILNISKKQLRSFINYVPQIPYTFSGTIKE
                     NLLLGNRTTITEKDIVTACKTAMIHDDIMHLPLGYNSKLDENATTFSGGQKQRLTIARA
                     LLSSAKVLIFDESTSGLDVLTEEKLIKNLMALSSKTIIFIAHRLSIARITNNITVIDNG
                     KIVEQGSHKELLKNKSLYFKLMQTQ"
     CDS             complement(6612..7385)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MDYHLLVCDDDRTQAKNIATLLKMSSIILEEQDIHPTIDLIATDA
                     ESVLDYLEFNSDLNNIIAFLDIQLDENSSSKGGLDLAQKIKTLNEKAQIIFITTHEELA
                     FLTFQRRINPLDYITKTTNQRDLQRRLTETLELAIRKLNEFNYIKKNTFSYKVGTRIIN
                     VNFSNILYISTTKFPHKLKIVTSNGQGEFSGDIKTIEQNYPLFFKASQSSLINLQNVET
                     INTKKRLIKFSNNDCLNYSRSRAKELNNLYKNLTC"
     CDS             complement(7398..8660)
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MNILIQIISVIQALTFELLIFLYLIKIKVTKRDTFRLTIIFTILF
                     LMIGLGYIGAYLSTILEGGFLYFYFKNRTPKPKLIGAILLTLTTSILTDFSTFTIDKVL
                     SLPTSYILFIDPIFYLFIFILFYHYHPLDKIEDKNATINLWILFYLFITLNIAGFIIFT
                     TPRVTPAFIVIFCLLVLQCSFTVFIYRISRQIQQKKLQLQEKKDLLFLIQNLEENQSKL
                     RRFKHDYQNLLNSLKLSAIHGDNQALLDKLENYSRDNLGKDSLWQFQDTKNIKDDVLRS
                     IFISKLNSIYQKDIKYHFECLTEINDLPNIDLFDLIRIIGIAYDNALEECETLKKLGAR
                     TVEINSMLYQSAPNKLEFEIKNTCRKQLSTNKLHQEGITNKANHEGLGLATVKKIANKY
                     HNVYIAYSSDNGYFTFTISIE"
     CDS             complement(8673..8810)
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MKKLSTQQLSLIKGGYGYALTFKSVNNNTYTYTNKIISSLRHIFH
                     "
     CDS             9177..9383
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_11"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.6e-16,
                     bitscore: 51.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLEDFQLKQILGGKNSWQQNVYGSVGAAAAGAGLGAAICGPAC
                     GFVGAHYGAIAWAGVTGATHGFH"
     CDS             9417..9605
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_12"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.3e-11,
                     bitscore: 36.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQLKNEQLEFILGGNRWGNATIGAMSGAARGVKWCRPAGAWGMA
                     GCAVVGAGVGGYFGYHS"
     CDS             9625..9927
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MKKIIKNNKWNIIAILIFFGLCIYYVYDKNIVMASDSLLGAIIWL
                     ISCLNKKYSYLAGIALISYAVFILIIRVDLWPGAVACIVIGLFILFFYLKKLKKQ"
     CDS             complement(10141..10395)
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MEILADEFNIDRLAIVGGGKINGGFLEAGLVDETSILIGAGADGR
                     TGQPSLFDGRPESGRPIALQLKDVESYEDGAVWLRYLVK"
     CDS             complement(10525..10809)
                     /locus_tag="ctg2_15"
                     /transl_table=11
                     /translation="MNKPYIIVHMMTSVDGRIDCGMTAQLAGEPEYYSTLDSLNIPTRI
                     SGRVTAETELTRDGKFNPQNKEILGKTDFARNATADSYNIVVDTKGTLQ"
     CDS             complement(10910..11839)
                     /locus_tag="ctg2_16"
                     /transl_table=11
                     /translation="MSIGQIFNQVVIIFLLMLLGAVIRKLGFLHPQSINDLTNITLYFL
                     SPIVIIKAFEQPFSRSRFYQLLLLIAGVFLTYFVSILIAKLLFHKVKDQNIRQIATYGS
                     IYSNNGFMGVPLAQGLFGSVGVFYAVASMIGFNVMSWTQGIGIFQKRQPHDWRTQLKKI
                     ILNPNIIAIIIGLFLFISSFRLPKLIAGFIDYTSPAFTPLSMIVIGSNLANLSIKNIKL
                     PTALWGSLFVRNIFFPILGTIILLLLGITGVPLFTTVILSACPVAGLVVLFTLQSNGDA
                     RPATVLMSISTILSLVTIPLVYWFASLW"
     CDS             11942..12664
                     /locus_tag="ctg2_17"
                     /transl_table=11
                     /translation="MLISNKDGKGNDFMSTLLVIQAHPHIENSLSLTVGKQFVDTYKET
                     HPNDQVIIRDLYAKGVPPLNDVTMEAWRKQKFDEPMTEEEKDLLKRHEEWLDEFISADK
                     YVFINPMYNHFLPAEMKQYLDLTAVAHKTFKYTSNGPVGLLTGKKAIHIQAAGSEYHKS
                     GKWGTVKFLIKKAFGIKSKESSALMDLGDMYLTNMLKFYGITDVEKLFVEGADAHRDQR
                     QKILDNALAEAKSMAKVF"
     CDS             12701..13195
                     /locus_tag="ctg2_18"
                     /transl_table=11
                     /translation="MNKVNEETITKIRHTIELLRVQHSNIHGSQEQQWIQEHLTDEKLK
                     QEVLNLSIVAFHILSALESGEQTGIEIAEKINVTRGGVTRAAKKLLQYDLILATKHSDD
                     KKKIYYSLTDEGKKLAKVHDQMHETIKRELVDKLTAKYSMDDLKIVANFLDDLYQLEQK
                     F"
     CDS             13277..13957
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 209.6; E-value: 7.2e-64)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_19"
                     /transl_table=11
                     /translation="MKKAVIMLVEDEESLASFLITELELEGYGVIWAKDGREALEIFKE
                     KDITLILLDWMLPIYDGLTVLRRIRQSSNVPIIMITARSQTSDISMALDQGLDDYITKP
                     FEIEELLARIRVVLRRLGQEKAEKYDYKFGPFEINLLKHQFMVDGKRVHLTPKEFSLMV
                     ALIKEPGVVQTRDDLLNEIWGYDFDGQTNTVDVYIRALRNKLGKYRDLIKTVRGIGYVL
                     GDEQ"
ORIGIN
        1 aacttaatca cattgaattg actggagcgt cttggacata ttcataagtc cgagttgttc
       61 cagttttcta ttagttagag aatagctcaa ggtcttactg tgtgcagttc gccagtatcc
      121 cttgcgggta ctagcgaaga catatgcatc atgctgagac agccccagct tctgtaaatt
      181 agttacctta gttttaaact tcttccattg cttccagata tactgcctta ttcgggctct
      241 caaccacttg tcaaggcgtt gaataaagtc agttagtttc ccaattgagt agtactgaag
      301 ccacccacgc atttttcggt gaatttcttc aaacattctt gtcagagata ttccacgatt
      361 acgtttagtt aataacttca atgctttcct tactcgttgt tgcgattgtt tagctggacg
      421 ggcgtaggcc ccattgtggt ctacacccaa cgaaaagcca agaaacttca accgtaacgg
      481 gctaccgact ttggttttat ctgggttcac tttaactttc aattgctttt ctagaaaccg
      541 ggtaatgctt cgcattactc gttctccagc tcgttgactt ttaacataga tgttacaatc
      601 atccgcatag cgcacaaagt ggtgaccacg tctagtcaac tctttgtcca actcatttag
      661 atagatgttc gccagtaatg gtgacaatgg tcctccttgt ggggttcctt tttcactcct
      721 agcgaaaagc tcatggtcta agactccact agttagaaac ttacgaatga gtcttagtgt
      781 ccatgggtca tcaatatatt gttggagata cttaatcatc aagtcatgat taacgttatc
      841 aaaataggct tttagatcta agtcgacaac tcttcgataa ccttgattat aaagatctac
      901 tacttttgca atagcgtcat gggccccacg gtggggacga aagccaaaac tattatcaga
      961 gaaaacgcgc tcaaagatag gcgtaagaat ttgggccaca gcttgttgaa ccattcggtc
     1021 caccaccgtt ggtattccaa gttttcttac cccaccatta ggcttcggaa tttctacccg
     1081 tttgactggt gctggtttat acttgccctc acgcaaacta gcgatcagtt ccgtcttatt
     1141 ttctctgaga tatggcaaaa ggtcattgac tgtcatacca tcaatgcctg ctgccccttt
     1201 gtttctctta actcgcaaat aagcctgatt aaggttattg cgatccaaga ctaagtcttg
     1261 gatagtgaca ctcatacctt taccttcacc ataatcggta ctacgcgccc ttgtgtactt
     1321 tcggttttcc aaacctatcc tcggcaagcg gtcagcttgt tgtcctgttt tctgcgattg
     1381 tcgcacctga ttacacctcc gatataagtt acaagttatt gtcgttcagt ccttcgtctt
     1441 taagactact atgacctcgg ctgactcctg acttactcaa cgttacatca ctgcaccgct
     1501 tgcttctgtg gaaatttatc ttattcctct tgtcggaagc gtgtaagtca ggcctccccg
     1561 ggtaagaata ttaactttca taccatatca ccgttagctt tactgagacc aacttcgagt
     1621 agtattggac ttcaacttgt ttagcagtct tatccagtta atttcagcct tatagctact
     1681 tcttgttcat cggtgcagta ctttgcctta gacttccttc agattccacc tcacagtgga
     1741 cacccttgtc ctcagctcat ggttccaact actatggccc atagcggact ttcaccgcct
     1801 agctaatacc catgccgggc gcactaataa aacagcgatg acaaataaat gccaccgctg
     1861 aaataacatc tcgcccacct cctcttggaa ttaagtggag tttaaccaag taattcctca
     1921 attaggcgtt tgagagcctt tttgattgca acctttacaa aatgtagcag ttgcttaacg
     1981 agcccattcg gcacgataat gataaagatg caccaatgca attgggacac ctcccaactt
     2041 gcacatattt gtaggttcgt tacacctaac agcgtgcttg actattgtat catagaatta
     2101 ctgtggtata attaaaacat aatgataaag atgccggtgt gcaaaatgga ttcagttcgt
     2161 tacttaatcc gtaccggtaa acagggtgcc ttaatcggca tcctttttta ttataaaaga
     2221 atgataaaag agattagcta tagtaaaaaa ctaatctctt ctaataggta aatcatattt
     2281 tatctgtgat tttttatgaa ctttaatcta agttggtcca cttacataca aggctaaagc
     2341 gctaagcaat gggtgctaga agaaccaacc tactatatgg aacgatagat ctttaaataa
     2401 aaattttcta agtctttgtt gaactaaagg acttagagaa tttttttgat gttatagctg
     2461 cttattttcg caagaattta ttatccttat ccggtaaatt ttcggggaca aagcgttctg
     2521 cgcgcatgtg taaattatat ttttcacgca acttcgctaa ttccgccatc attggtgaat
     2581 tatgatcagc gtctaatgct tcttgacttt cccaggtatc aatcaaaaga atcgtgtggg
     2641 gatcatcaag tggttgaaaa tattcgtatt ttagattacc aggttgttga cgaattttgt
     2701 cagcaattcc ccgctcctcc atttcctggg caaacttttt ggcattatca ccttcaccag
     2761 tgtagtaaag attcattgta aaactcatgg ttattcctcc tattttttct acaggtcaat
     2821 aatttctggt tcaaaatcaa cctgcttaag aaatttgaac aagtcatcgg tcttaataaa
     2881 aattgtatga gtattttcat tgggatggaa agtctgaatt ggttcattga caatatcctt
     2941 gtcaaaatat acctttacat tatgagcttc attattcagg aggccaaatg gtgaaacaat
     3001 tcctggtgct aagccaagct gttcttgcag atattccggt cgagccattg aaaccctttt
     3061 agctccagtt agggccatga atttatgaaa gtccattggt tttttatcat ccataataac
     3121 catatagaaa ttctttttct tccctttcag aaacatggtt ttagtgcgaa caccttcatg
     3181 accagcgata tatgcatcag cttcttcggt ggtgtgagca gcagggtgat caatcacagt
     3241 atagtcagtt attccgaaat tttttaatgc atccttgact tgctgatagg ttcctaatgt
     3301 cataatttcg ctccttaatt aaatctttct tcatgaaacg cttacattaa ttataaagca
     3361 aattaagcga ttagatgagc caatagtttt tctgtaaaac ttgtttcaat taatactagg
     3421 gatcgaactt aatattttta tggaagaaat tttaatcgaa gctcttgtta cttagtagga
     3481 aatgtcataa taaccattat tatttataat tacaatatgt tattatatga tcatgaggtg
     3541 attataatga gttcgaaagt tcaagtaaac attgatccag aattaaaaca gtcagcggag
     3601 aatattataa aagaaattgg tttaacccca acagctgtaa taaatggaat gtataaacaa
     3661 atagttgcca cagggaaaat acctcttagt ttttctttga catcaagaca aagggcggag
     3721 ttggagttaa gagaagtatc caagaaaatt ccagttcgtg aagttaagac aaaagaggaa
     3781 tttgaggaat tttttaatga ggactaatca aatttatact gcttatgtat cttggggttt
     3841 agatgggaaa aggcgtccag ttttgatcgt agaagataaa aataaaaatg tcttttgtta
     3901 tagaataaca agtaaataca aaaacaaatc tgagagaatt aagaaaaatt attttcctct
     3961 tatggattgg aaaatagagg gacttgataa gcagtcatat attgatgtgg gagatattat
     4021 taagctttca aaagaacatg tgtcttttag gcttgttgga gaattgtcaa tacgtgatat
     4081 tgaagcgctg gtagaattta ttcgcaatcg atatgagata taaaaataaa aacgtcgcag
     4141 aaaaattctg tggcgtttta ttaatgtctt tagacctagt tgagtgcgtg agcagagcga
     4201 atgcacgaaa caaaaaacca cctgctatgc gggtgggcga taaaattaga taaaaaagcc
     4261 tcttttgcct taagatgtag gtgttcaagc caaagtcaat aagggaaaag aggtaataag
     4321 aatatggtta ataattaaac aagttagcca tataaaaagt atagatggaa aattatatga
     4381 ctattgtata agctaagaat gcttaatcgt tatgcaaaat tgaataaaga cagcctctat
     4441 ttattgtgtt tgcataagtt taaaatataa cgatttattt ttgagaagtt ctttatgaga
     4501 accctgttca acaattttgc cattatcaat aactgtaata ttatttgtaa ttcgagctat
     4561 tgaaagacga tgggcaataa agatgatcgt ttttgaagat aatgccatga gatttttgat
     4621 tagtttctct tctgttaaaa catcaagtcc actagtagat tcatcgaaaa tgagtacttt
     4681 tgctgatgag agtaatgctc tcgctattgt aagccgctgc ttctgccctc cagaaaaagt
     4741 tgttgcattt tcatctaatt tactattata tcccaacggt aaatgcatta tatcatcatg
     4801 tatcatagcg gttttacatg cagttacaat atctttttca gtaatcgtag tgcggtttcc
     4861 taataataag ttttctttaa tcgttcctga aaatgtataa ggaatttgtg gcacataatt
     4921 aataaaagaa cgtaactgct ttttagagat atttaaaata tttagattat taataagaat
     4981 ttcaccattt gaaacatcaa aataatttac taataatttc attaaggttg atttaccaga
     5041 gccacttaga cccacgattg tcagtttttc gccagactta atttttaagt taatattttg
     5101 taatatagga gaattgtact cgtagctata agaaacattt tttaactcga ttgttccatt
     5161 ttttaatgaa tgattatgtt tagttgtatt tttaaattcg tctttaacca tgtatatctc
     5221 atttaaacga ttattagcaa cttgcgcact ttggattttg ggttgtaggt taatgatgtt
     5281 ttgaagggaa gttgtaaagt aaactagtaa tgcattatag gtcattaatt gtccaattga
     5341 taattcattt ttaataacct ggttagctcc aacccataaa atgataaggt taagcgaaag
     5401 ttgaacaaaa gttttgagtc cttgttgtat attatttaat ctagtgtgga ctaatgactt
     5461 atgtaagaaa tcattaaatt cgttagtaat cttgtcagaa cgaacttctt cgcaattaag
     5521 agatttaata gtttcgattc ctctaatatc ttctataatt gatgcactta ctgttgcgtt
     5581 actttccatt tctttttggt ttagtttcct aaaattacta gtaaatgaaa aaattatcag
     5641 agaataaata ggaataataa gcatagtaat tccgaataat ctaatatcct gtaaagcaag
     5701 aactgtgcct ataattatta aaatagtggc atctaaaaag atagatataa ttgcactgac
     5761 aagagcatca attactttat tcgcgtcagt aaaacgagat agaatatcac cagtctttct
     5821 agtagagaaa aatgccattg gaagtcttaa aacatgcttt atatagttta ggataataat
     5881 tttagatagt ttctgcccta gaattgctaa taagtaatcc cgagaaaaag taaatagaga
     5941 gttaaaaaga taggcgaaca atagtccaat actaataatt gctaaaggat cttgaagttt
     6001 attaggaatt aatgtgtcaa gtaaagtttg tagataataa gaatttaaaa tattaagaaa
     6061 cgttacaata aaagctgctg taataattcc aaaaagtagg gatttttgtt gaaaaagtgg
     6121 tcgacataat cttttaaaag tggggatttt ttcttgaata gctttatagt ttttacctgg
     6181 ttttgcaaaa atagcaattc cggtccattc ttcaaaaaaa ttgaccttag gaatacgttt
     6241 aacttgtata ttaggatcag gatcagcaat aaaaatatgt tttttggaac ttttaaaaac
     6301 aacacaatag tgaagtaggc cactgtcttt ttttatgaga tgagcaataa aaggataaat
     6361 tacatctttt gaatcaaata aactagcatc tgcttgatat gcttcaacat ccatttttaa
     6421 cttttctgct gcttttacaa tcccaagtgc agtagttcca tcagtagtgg tttttgtaaa
     6481 ttttcgcaga gttgctaatg aaattttaga gccgtaatta tgaagaatca ttgctagtgc
     6541 tgctactcca caatcagctt catccacttg atttatatag tgtcttctaa agttatacat
     6601 aaagtgcctc gttaacaagt tagattttta tatagattat ttaattcttt agctctgctt
     6661 ctagaataat ttaaacaatc attgttggaa aacttaataa gccgtttttt ggtattaatt
     6721 gtttcaacat tttgtaagtt aattaagcta gactgcgaag ctttgaaaaa tagaggatag
     6781 ttttgttcaa ttgttttaat atcacctgag aattcccctt gaccattaga tgtaacaatc
     6841 tttaatttat gagggaattt tgtagtagag atataaagga tattactgaa gtttacattt
     6901 ataatccttg taccaacttt ataactgaac gtattttttt taatatagtt aaattcattc
     6961 agttttctta tagctagttc tagggtttcg gttagccgtc tttgtaaatc tcgttggttt
     7021 gtagttttag ttatatagtc caacggatta attcgacgtt gaaaggtgag aaaagctagt
     7081 tcttcatgcg ttgtaataaa gattatttgt gctttttcgt taagtgtttt tatcttttga
     7141 gctaaatcta gaccgccttt tgaactggaa ttttcatcta actgaatatc taaaaaggca
     7201 ataatgttat ttaaatcact attaaattca agataatcta atacactttc tgcatcggtt
     7261 gcaatcaaat caatggtcgg atgaatatct tgttcttcaa gaataattga tgacatttta
     7321 agtagtgtag cgatattttt tgcttgagtc ctgtcatcat cgcagacaag taaatggtag
     7381 tccataagta ttcctttcta ttcaattgaa attgtaaatg taaagtaacc attatcagag
     7441 gagtaagcaa tatatacgtt gtggtatttg ttagctattt tttttacagt tgctaatcct
     7501 agcccttcat gattagcttt atttgtaatt ccttcttggt ggagtttatt agtgctaagc
     7561 tgctttcgac aagtattctt aatttcaaat tctaacttgt taggagcact ttgatacagc
     7621 attgaattga tttctacagt acgtgctcct aactttttta aggtttcgca ttcttcaagg
     7681 gcattatcat aagcgattcc aattattcga attaaatcaa ataaatcgat atttgggaga
     7741 tcattaattt cagttaaaca ttcaaaatga tatttaatat ctttttgata aattgaattt
     7801 aatttactaa taaagatact tcgcaagaca tcatctttaa tgtttttagt gtcttggaat
     7861 tgccaaagag aatctttacc aaggttatct cgagaatagt tttctaattt atcgagtaag
     7921 gcttgattat caccatggat ggcacttagt ttgagactat ttagtaagtt ttgataatca
     7981 tgtttaaatc gtcttaactt cgattgattt tcttctagat tttgaataag aaataacaag
     8041 tctttctttt cctgaagttg aagtttcttt tgctgaattt gtctgctaat tcggtatata
     8101 aagaccgtaa aactacattg aagaactagt aagcaaaaga taacaatgaa ggctggtgtt
     8161 acccgtggag ttgtaaaaat aataaatccc gcgatattta aagtaataaa aagataaaat
     8221 aagatccata aattaatagt tgcatttttg tcttcaattt tgtctagggg atggtaatgg
     8281 tagaaaagaa tgaagataaa taagtaaaag attggatcaa taaatagaat ataactagtt
     8341 ggtagtgaga gtactttatc aatagtaaat gttgagaaat cagttaaaat tgatgtggtt
     8401 aaagttaata ggatagcacc aattaattta ggcttagggg ttctattttt aaaatagaaa
     8461 tataagaagc caccctctaa tatcgttgac agatacgcac ctatataacc taagccaatc
     8521 ataagaaata agatagtgaa aatgatagtc aaacgaaatg tatctcgctt agtaactttg
     8581 atttttatca gatataagaa tattaaaagt tcgaaagtaa gagcttggat tactgatata
     8641 atttgaatca aaatattcat acttaaaatt aattaatgga aaatatgtcg taagctgctt
     8701 atgattttat tggtgtaagt atatgtatta ttatttacag atttaaatgt gagtgcataa
     8761 ccgtaaccac ctttaattaa agatagttgc tgagttgata gttttttcat aaataaatct
     8821 ctcctattgt tttatcagtg atttatttta acaggatata tcgataaaat cataaatgat
     8881 caaaagtggt tgtttagcat tcaaattttg taagaaataa atcggattgt ttcaattaat
     8941 aaagtctttt atttaataag tattaaattt ttatttactt tgttcttcta aaagggaaat
     9001 tgttattata gcatatttaa gtttaactaa attagtgatt cagatttaag agttatttca
     9061 gcatatttag gggaagtgct tgaatttgaa taaaaatcgt tgaaattaga agattctata
     9121 gaactttgtg aaagaattgt atgattaaat tgaaaaatta taaggagatt atttttatga
     9181 agaaattaga agattttcaa ttaaaacaaa ttttaggtgg taagaactca tggcaacaga
     9241 atgtttatgg ttctgttggt gcggctgctg caggtgcggg attaggcgca gctatttgtg
     9301 gcccagcctg tggattcgtt ggtgcccatt atggtgctat tgcatgggca ggagtaactg
     9361 gcgctacaca cggatttcat taaaaattta gaaataaaag ggaaggagaa ataataatgc
     9421 aacaattaaa aaatgaacaa ttagaattta ttcttggcgg aaatcgttgg ggaaatgcaa
     9481 ctattggtgc aatgtcagga gcggcgaggg gtgtaaaatg gtgtcgtcct gctggagctt
     9541 ggggtatggc tggttgtgca gtagttggcg ctggagtagg tggctatttt ggttatcata
     9601 gttagtatct tattatagaa ttaaatgaaa aaaattatta agaacaataa gtggaatata
     9661 attgcaatat taatattttt tggcctttgt atatattatg tttatgataa aaacattgtt
     9721 atggctagcg attccttact gggtgcaata atctggctga ttagttgctt aaataaaaaa
     9781 tatagctact tagcaggaat agcactaatc tcatatgccg tgtttatttt aattattcgg
     9841 gtagatttat ggccgggagc agtcgcatgt atagtaatag gattgtttat cttatttttc
     9901 tatctaaaga aacttaaaaa gcaataatct agagaataaa aggtatgatc ccggttaaat
     9961 attggagtca taccttttta tcctgcactt caactttata attttcatta cgcaagactc
    10021 ttcgttactt tagtttaaat actcaaagta tatgcgatag ttcttgcgtt ttcttgtttt
    10081 taaagcacaa atgcatagaa tcacagtaat ttaccacgac cccatgcatt taaatttcag
    10141 ttacttaacc aaataccgta accagacggc gccatcttca tagctttcaa catcttttaa
    10201 ttgcagagcg attggacgac cgctttctgg acggccatca aaaagacttg gctgaccagt
    10261 tcgaccatca gcaccagcac caattaaaat actggtttca tcaactaatc cagcttcaag
    10321 gaaaccgcca ttgatttttc caccgccaac aattgctaaa cggtcaatat taaattcgtc
    10381 ggcaaggatt tccatcgctt tagccaggtc gatttgatct ttcccagttg cgatccatga
    10441 aatattttgc cgatcaaggt aatctttcgt aacttgttca ttcgtaataa tgaggtgagg
    10501 aaagttatta ccattttcct tgtctcattg taaagttccc ttagtatcga caacgatatt
    10561 ataactatca gcagttgcat ttctagcaaa gtcagtctta ccaaggattt ctttgttttg
    10621 cggattaaat ttaccatcac gcgtcaattc ggtttctgca gtaacacgtc cactaatcct
    10681 tgtaggaata tttaaactgt ccaatgtaga atagtattcg ggttcaccgg ctaattgggc
    10741 cgtcattcca caatcaattc gtccatcaac tgatgtcatc atatgcacga taatatatgg
    10801 tttattcatt tataaagcct ccacgtatct aactccatca tagattaagg aggctattat
    10861 ttgaaatgct tattatattt aatactttat tcaaagattg tatatatcat taccatagac
    10921 tagcaaacca atagactaat ggaatagtta ctaaactcaa aatggttgaa atactcatta
    10981 agacggttgc tggccgtgca tctccatttg attgtaaggt aaaaagaacg actaatcctg
    11041 ctactggaca tgcactaaga attactgtgg tgaagagtgg aacaccggtg attcctaata
    11101 ataataagat aattgtccct agaattggga agaaaatatt ccttacgaag agacttcccc
    11161 agagtgcagt tggtaatttg atatttttaa tacttagatt ggcaagatta cttccgatga
    11221 caatcattga tagtggagta aacgctggac tggtgtaatc aataaaacca gcaattaatt
    11281 ttggcaaccg aaaagaacta atgaatagga aaaggccaat aataatagcg ataatattag
    11341 gatttaaaat aattttcttt aactgtgttc tccaatcatg aggctgccgt ttttgaaaaa
    11401 ttccaattcc ctgggtccac gacatgacat taaaaccaat cattgaggcg acagcataga
    11461 agacgcccac gcttccaaaa agtccttgtg ctaatggaac gcccataaag ccattattag
    11521 aatagatact tccataagtt gcaatttgac gaatattttg gtcctttact ttatgaaaaa
    11581 gtagttttgc aatcaaaatt gaaacaaaat aggtcagaaa gacaccagca atcaatagta
    11641 ataattgata aaatcgtgat cgcgaaaacg gctgttcaaa ggccttaata attacgattg
    11701 gcgataaaaa gtagagtgta atatttgtta ggtcattaat tgattgtgga tggagaaatc
    11761 cgagctttct aataactgcc cctaaaagca ttaataagaa aataatgacg acttggttaa
    11821 aaatttgccc aattgacatt gcaccacttc cttcagttaa aaatcacaat tactatttta
    11881 taacaaaaat ctcccctttt tgttgacaag caacataaaa cgagtaaaat atatcaaaaa
    11941 gatgttgata agcaacaaag atggaaaagg gaatgatttt atgagtacat tattagtaat
    12001 ccaagcacat ccacatattg aaaatagtct ttctttaacg gtcgggaagc aattcgttga
    12061 tacctataag gaaacgcatc ctaacgatca agttattatc cgtgaccttt atgccaaggg
    12121 cgtcccaccg ttaaatgatg tgacgatgga agcatggcga aaacaaaaat ttgatgaacc
    12181 aatgacagaa gaagagaaag atcttctaaa gcgtcatgaa gaatggttag atgaatttat
    12241 tagcgccgat aaatatgtat ttatcaatcc aatgtataac catttcttac cagcagaaat
    12301 gaaacaatat ttagacctta cagcagttgc tcacaaaaca tttaaatata cttccaatgg
    12361 gccagttggt ttattgacag gcaaaaaggc aattcacatt caggcagccg gtagcgaata
    12421 tcataaaagt ggaaagtggg gaaccgttaa attcttaatt aaaaaggcat tcggaattaa
    12481 gagcaaagaa agttcagcat taatggatct tggtgatatg tatttgacga atatgctaaa
    12541 gttctacgga attactgatg ttgaaaaatt atttgttgag ggtgccgatg ctcaccgtga
    12601 tcaacggcaa aaaattcttg ataatgcatt agcagaagca aaatcgatgg cgaaagtatt
    12661 ttgatataat ggccttaata ataaatagtg aggccaagta atgaataaag taaacgaaga
    12721 aacaataact aagattcgcc atacgattga actattacgc gtacaacaca gtaatattca
    12781 tggctcacaa gaacagcagt ggattcaaga acacttaacc gatgaaaaat taaagcaaga
    12841 agtacttaat ttgtcgattg tcgcattcca tattctgtcg gcacttgaat caggcgaaca
    12901 gacagggata gaaattgctg aaaaaataaa tgttacacga gggggagtta cgcgagccgc
    12961 aaaaaaactc cttcaatacg atttaatttt ggcgactaaa cattctgacg ataaaaagaa
    13021 aatatattat tcactaacgg atgaaggaaa gaaactagca aaagtccatg atcagatgca
    13081 tgaaacaata aagagagaat tggttgataa attaaccgca aaatactcaa tggatgattt
    13141 aaaaattgtt gctaatttct tggatgattt atatcagctt gaacaaaaat tctaattatc
    13201 agcaaaaaag tttcatatga aactttttta ttttccttca gtacaaaaca gctaaaatag
    13261 tatataggac aaaataatga agaaagctgt cattatgtta gttgaagatg aggaaagtct
    13321 tgctagtttt ttgattactg agctagaact tgaaggctat ggagtcatct gggccaaaga
    13381 tgggcgtgag gcactcgaaa tatttaaaga gaaagatata accttaatct tattagattg
    13441 gatgctccca atttatgatg gcctcacagt tctacgccga attcggcaat caagtaatgt
    13501 gccgattatt atgattacag ctcgtagtca aacttctgat atcagcatgg cactagatca
    13561 aggcttggat gattatatta ctaaaccgtt tgagattgag gaacttttag cacgaattag
    13621 ggttgtatta cgacgattgg gtcaagaaaa agcagagaaa tatgattata aatttggacc
    13681 atttgaaatt aatttactga aacatcaatt tatggttgat ggcaagcggg ttcatttaac
    13741 gcctaaagaa ttttccctca tggttgccct aattaaagaa ccaggagtcg ttcaaacccg
    13801 tgatgacctt cttaatgaaa tatgggggta tgattttgat ggtcagacca atactgttga
    13861 tgtctatatt cgtgctttgc gcaacaagtt aggcaaatac cgcgacttaa ttaaaacggt
    13921 gcgagggatt ggttatgtat taggtgatga gcaatgagta acacacatcc agtaactgca
    13981 tcgcggcaat taactcgtct tttcttaatg ttgtttgcag tgattttagt agttattaat
    14041 cttctttttg tggttaccgc cactaattta atctatcgtt atgctgatga tcaggcagaa
    14101 gaagtgattg agacaattga ggaagattgg cccgaaaatc aaaatcgcga aacttttttg
    14161 aatgcttatg ttgctcgtca agacgatgac gcaatcgaga tcactgatgg taaacgagaa
    14221 tatacctcac ccaaagccca taaaattttt aaacgaattg accagcgaaa tttagcgatc
    14281 aagaatctac agttaacccg acatggagtc tattatttac gacagcaaaa ggtccatcat
    14341 catcgaatcg taaaagtagc aattaatgtt gatgatttaa tcaaattaac aggctggctc
    14401 ttgatagtga ctttgttaat taaccttgca ataagcatca ttactctccc aatcattcat
    14461 cggttggcta aacgatggac ccgaccattg actagtttag atagtgaaat cgatgcaatc
    14521 acaccccaaa gtgatcgatt acaaacttta acaattccgc agcagccatt agaagtacga
    14581 aaagttgcgc agtcctttaa tcagc
//
