LOCUS       c00054_JAJGVW0..       11386 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJGVW010000160.1 Limosilactobacillus reuteri strain Cor124_1_1
            scaffold160, whole genome shotgun sequence.
ACCESSION   JAJGVW010000160
VERSION     JAJGVW010000160
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 16:48:32
            Original ID  :: JAJGVW010000160.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3807
            Orig. end    :: 15193
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11386
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[8807:10193](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6386
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..11386
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11386
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             412..1806
                     /locus_tag="ctg54_5"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLCLLVLVVSCMTIHQRRHFNKNVKIDNVAVGG
                     LTAKQALKRLQDNPQSPKIYVNNELVFKDKQSVAKFSSADKPKIVNALHSQYTFFPSSK
                     VKNIAVKPQSINQDEVSKIDQAVSQKVTELNNGRKAPVDAYAVYENGRVQVKPAVGGTQ
                     YSLDGLHNKVENEIAGGTIHLKPKYTTPLSANSKTVRNEKAKLEELSKRSVTYQVQNKK
                     YQLNCGEIITRATYQNGKYHFDTGAADSKINEINNTQATLGKSFEFRTHDGSVIKTTDA
                     GSYGWKISKKQAGKTLTNALVANKQTVNAKNEIYGKGYNQQGTGYNTTSNNGIGDTYAE
                     VSLADQHAWFYKDGKCVLSTDIVSGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVKYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFHDLQKN
                     EPVIIY"
     CDS             1820..1918
                     /locus_tag="ctg54_6"
                     /transl_table=11
                     /translation="MRPSAERAIMIAIACFVLTIIISFALSEGWIK"
     CDS             1930..2094
                     /locus_tag="ctg54_7"
                     /transl_table=11
                     /translation="MVDFDLETKKNLVIINLFYIGLIALYCILHAGPLNLLVFFGMLVI
                     ANVAEILIG"
     CDS             2240..3550
                     /locus_tag="ctg54_8"
                     /transl_table=11
                     /translation="MIQLTLAQSFFADYLNILEIINVYRLIVGKINAKKLLPDILVALV
                     IVLLPVFSNLNSLNVLFIIIYLWASDRLTSSKNIVLDSLIAMLNGVVMASLFDLVDHYT
                     YTFFLQGKTDIALLGWLIPINDLVITIVVAILAIKVVRPKLRWIRINFPRPIGLWQITA
                     ILFMLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCTTGFINFVKSSQQTQRQQQIID
                     KYQAQIANANQLNQQYNEIRRERHDTRNMLLSVQGYIRDHKDKEAEKLLATFLQNDTVE
                     KHYGEIDNALDKIKISGLHNLVKEKAYKIVEKGIPFSFEINAEIDELPGSEIKTARIIG
                     ILMDNAIEATFKQAKPYIQFALLKHSAEVYELVIANSIEQKLNINTALKFEHSTKEGHQ
                     GIGLSNVTQLVENDDHYSFSAEVKDKVIIMTCFIQGK"
     CDS             3558..4325
                     /locus_tag="ctg54_9"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEAYLAILDIELDNQLSGIDVAEQIRKKAEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGKQIESIADRLRIDIDEAYARYQNYVSSNQKHHEKITYEPIRGVKRQVDL
                     ENLYYIESVKNTNRRLRIVGKDIRIEYHGELNQVDSNHLLKVNQSTLINPKAIQEFNRK
                     ERIVYFDTNREIKVTVSYRKIKSLVDFLEKENH"
     CDS             4567..4725
                     /locus_tag="ctg54_10"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVKDVVNSLNKWAQSCYAG
                     YKDSPFH"
     CDS             5001..6386
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 119.9; E-value:
                     2.1e-36)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_11"
                     /sec_met_domain="TIGR01193 (E-value: 2.7e-171, bitscore:
                     563.1, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.4e-39, bitscore:
                     125.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYPYYVAQVDEADCGIASLAMILRNFGSIYPIAKLRDLARTT
                     KQGTTALGLLKAAKHLGLDVIPIQADLSLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFGRLWSGVSLLFSPAKGYTPQKEPLAGLMTMFRQLTNY
                     KKDISGIVIAALLITFISIVGSYYLQLIIDRFIPSKSINGLAILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGHVLFLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSDIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAVLVIQGRLSIGILMAFNALLAFFISPLQNIINLQPKLQEAKVANNRLN
                     EVL"
     CDS             6432..7151
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 201.1; E-value:
                     3.4e-61)"
                     /gene_kind="transport"
                     /locus_tag="ctg54_12"
                     /transl_table=11
                     /translation="LVGPINIQHVDYSYEYSRPILQDINLQIGCNDKLAIVGLSGSGKS
                     TLAKLLVGFYLPTQGQIEFNQHKTTKINLCDIRQYVHYLPQSPQLFSGTIKDNLLMGLD
                     HEVSAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALLTSAHV
                     LIFDESTSSLDPITEKRIVENLLEIEDRTMIFIAHRLSIAKKVNKVVVMRDGKIIEQGT
                     HQELLNHHQEYYNLWNA"
     CDS             complement(7340..7525)
                     /locus_tag="ctg54_13"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYIYLLLLFLWIAPFSDGSLPLDESLLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(7804..8232)
                     /locus_tag="ctg54_14"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLQAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSN
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             complement(8300..9295)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 298.6; E-value: 6.1e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_15"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTADV
                     DGLVIQQRSKVPADIYEKLHTNGLKQIATRTAGFDMVDIKKANENDLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSTEIHTATIGIIGVGRIGGTLAKL
                     LHALGATVLGYDTNPRTDLDRIVQFVSKEELLKQADVVSLHVDLNPASKGLLTANDFAM
                     MKPTAGLVNASRGPVVNTADLVTALKAGEIAAAALDTFEGEETVAAADRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMTILNGGKSPHEITL"
     CDS             complement(9297..10484)
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     2.5e-73. Score: 239.0. Matches aSDomain:
                     nrpspksdomains_ctg54_16_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 275.6; E-value:
                     1.1e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_16"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.6e-07,
                     bitscore: 22.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFAKLTPGGIREFDYQASAIPGIIKLTLGEP
                     DFNVPAAMKQAAIDSINANDSHYAPGNGTLALRQAIAHFMQDRYELEYDPENEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSSDDFVLTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTVKSTNLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKAVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNSLQKLGFELINPQGAFYVFAKIPKQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIASFINKEN"
     aSDomain        complement(9324..10376)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg54_16_Aminotran_1_2.1"
                     /evalue="2.50E-73"
                     /label="ctg54_16_Aminotran_1_2.1"
                     /locus_tag="ctg54_16"
                     /protein_end="387"
                     /protein_start="36"
                     /score="239.0"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPAAMKQAAIDSINANDSHYAPGNGTLALRQAI
                     AHFMQDRYELEYDPENEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSSDDFVLTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTV
                     KSTNLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKAVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNSLQKLGF
                     ELINPQGAFYVFAKIPKQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             10990..11211
                     /locus_tag="ctg54_17"
                     /transl_table=11
                     /translation="MRIDIKHYLEVNHLTIYQVSKCSGYGYTTLHKSFNKPQSSSTSLN
                     LRDLDALARAQDKSMWEVLKELEEHYLE"
ORIGIN
        1 agacaaccca agctgcatca actcaacaac ctgtaacagt ggaagatggg atgaacttta
       61 gctaccgggc tgcgcaaaaa gctggcgtga ttgataataa tacatctgtt gaagagtttt
      121 acaaaaatgc caaggaaggt aatggttctg taacctacaa cggtcaaact atttactaca
      181 aagctaaggg taataatcaa tatcaagtta caaccgctaa atagtttggt tactaaaaag
      241 tgtccggcat tttgtccaga cactttttta gtaaaaatac tatgaaagat gtaaaatata
      301 ctaattgttt gcgctttagt atataatgaa tgagcgtaat gaatatgttt actaagtgat
      361 cattcagtat agaaatatac ttaaaggttt ggatgttatt ggagtacttt tatgcaaaaa
      421 ctatctatta aacaactaat aataattaca ttgtgcttat tagtgctggt ggttagctgc
      481 atgactattc accagcgtcg tcattttaat aagaacgtta agatcgataa tgtggcagtt
      541 ggtggattga ctgctaagca agcattaaag aggttacaag ataatccaca atcgccaaaa
      601 atttatgtta acaatgaatt agtatttaag gataagcaat cagtagcaaa gtttagtagt
      661 gctgataaac caaaaattgt aaatgcatta catagccaat acactttttt tccatcatct
      721 aaggtaaaga acattgcggt taagcctcaa agcattaatc aagatgaagt atcaaagatt
      781 gatcaagcag taagtcaaaa ggtaacagaa ttaaataatg gtcgaaaagc tcctgttgat
      841 gcttacgcgg tatacgaaaa tggccgagta caagtaaaac cagcagttgg tggtacgcaa
      901 tacagtttag atggtttgca taataaagtt gaaaatgaaa ttgctggggg aacaattcat
      961 ctgaagccaa aatatacgac tccactttct gcaaatagta aaactgttcg gaatgaaaaa
     1021 gcaaagctcg aagaattatc aaaacgatct gtaacatacc aagtacaaaa caaaaagtat
     1081 caattaaatt gtggtgagat tattaccaga gcaacctatc aaaatggaaa ataccacttt
     1141 gacactggag cagctgattc aaagattaat gaaattaata atacccaagc aactcttggc
     1201 aaatcatttg aattcagaac ccatgacgga tcagtgatca aaacaacaga tgctggctca
     1261 tatgggtgga agatcagtaa gaaacaagct ggaaagactc ttacgaatgc attggttgca
     1321 aataagcaaa cagtaaacgc caaaaatgaa atctatggta aaggttataa tcaacaagga
     1381 actgggtata atactacaag caacaatggt ataggggaca cttacgccga agtttcactg
     1441 gccgaccaac atgcctggtt ttataaagat ggtaagtgtg ttcttagtac tgatattgtt
     1501 agtgggacga ataataagga taatgaaact cctaagggtg tctggtatat catgtatcag
     1561 caaacaccgt ctgtccttcg aggccttaac gatgatggtt cgaaatatgc aagtaaggtc
     1621 aaatattggt caccatttac tgatagtgga tgtggatttc atgatgcaag ctggcgtcat
     1681 gactggtcaa aacaggctta tcttgctaaa ggcggtggat cgcacggttg tattaacatg
     1741 catccagatg ttgctggtca agcctttcat gacttacaga aaaatgagcc tgtaattatc
     1801 tactaaagga gaatttatta tgcgcccaag tgctgaacgc gcaattatga ttgcaatagc
     1861 ttgctttgtt ttaacaatta ttatttcttt tgcattatca gaaggatgga taaagtagga
     1921 gttagttata tggtggattt tgatttagaa acgaagaaaa atttggtaat tattaatctt
     1981 ttttatatcg gattaattgc cttgtattgt attttgcacg caggcccact taatctttta
     2041 gtattttttg gaatgttagt gattgcaaat gtagcagaga ttcttattgg gtaaaattag
     2101 aataggggaa agtaattatg tcaaacaata gatataaaat tttatcaaaa caagatttat
     2161 ctaagattgt tggaggatgg ggatactcac ttgtatttag aaatggatgg acaaatttct
     2221 taaataagtg gaaaaaaaga tgattcaatt aacgttagca caatcttttt ttgcggatta
     2281 tctaaatata ttagaaataa taaatgttta tcgtttaata gtcggaaaaa ttaatgcgaa
     2341 aaaattattg ccagatattt tagtagcatt agttattgta ttgcttccag tattttcaaa
     2401 cttaaactca ttaaatgtat tgtttataat tatttatcta tgggctagtg atcgactgac
     2461 ttcttctaaa aatatagtgt tagatagttt aatagcaatg cttaatggag ttgtaatggc
     2521 atctttattc gatttagtag atcactatac ttatacgttt tttttacaag gaaagacaga
     2581 tatagcactt ttaggatggc ttattccaat taatgattta gtcataacta ttgtagttgc
     2641 aatcttagca attaaagtag ttcgtcccaa actgagatgg attaggatta attttcctcg
     2701 accgataggg ttatggcaaa ttacggcaat tttgttcatg ctttatgtgt ggttaactgc
     2761 tattgccgaa aaggacgggg tagcaaataa gtatgcttcg ctgttgttaa taatgtattt
     2821 gataattatc gtagtatgta caaccgggtt tattaatttc gttaaaagca gtcagcaaac
     2881 gcaacgacag caacaaatca ttgataaata ccaagcacag attgccaacg ccaatcaatt
     2941 gaaccaacaa tacaatgaga ttcggcgtga acgtcacgat acacgtaata tgcttctcag
     3001 tgttcaaggc tatattcgtg atcacaaaga taaggaagca gaaaaattgc tagcaacgtt
     3061 tcttcaaaat gatacagttg aaaagcatta tggtgaaatt gataatgcat tagataagat
     3121 taaaatctct ggcttgcata atcttgttaa ggaaaaggct tataaaatag tagaaaaggg
     3181 tattccgttt tcgtttgaaa ttaatgctga gatcgacgag ttgccgggtt cagaaataaa
     3241 aactgctaga attatcggaa ttttaatgga taatgcaatt gaagcaacat ttaagcaagc
     3301 taaaccatat atccagtttg cattgcttaa gcatagtgca gaagtttatg aattggtaat
     3361 tgctaattca attgagcaaa aacttaatat taatactgca ctaaaatttg aacattcgac
     3421 taaggaaggg catcaaggaa ttggcctttc aaatgtgaca cagttggtag aaaatgatga
     3481 ccattattct ttttcagcgg aagttaaaga taaggtaatt ataatgactt gttttattca
     3541 gggaaagtga gaataaaatg ttaaaagtaa ttattttgga aaatgatgat tatcaagctg
     3601 attatactga gcgtctagtt tctcagcgaa aattgattaa cgctactcca aatagttatg
     3661 acatagaatt atatttgcgg acaaatgatc cgcaagaagt gattgatagc atcaaagatg
     3721 aggcttattt ggcgatttta gacattgagc tagacaatca acttagtggg attgatgttg
     3781 ctgagcagat ccgcaaaaaa gctgaatttg ccgaaattat ctttgtaact gcatatcaag
     3841 aatatttacc ttatactgtt tcgcgccgaa ttgagccatt cgactatata tcaaagggga
     3901 aacagattga atcgattgcg gatcgactcc ggattgatat tgatgaagca tatgctcgct
     3961 atcagaatta tgtaagtagt aaccaaaaac accacgaaaa aattacctat gaacctattc
     4021 gtggtgtaaa acgccaagtt gatttggaaa atctttacta tattgaatca gtaaaaaata
     4081 caaatcgacg gttacggatc gttggaaagg atattcgaat tgagtaccat ggtgaactaa
     4141 atcaagttga tagtaaccat ctattgaaag ttaatcagag tacgctgatt aatcctaaag
     4201 caatccaaga atttaatcgt aaagaacgta tagtttactt tgatacgaat cgagaaatta
     4261 aagtgactgt tagttatcga aaaataaaat cattagtcga ttttctcgaa aaggaaaacc
     4321 actaactact ttattttcaa agaaactgtg acaaaaagct gtcgtggttt ctttttttat
     4381 tgtcaaacaa tttcagtaaa cgttttcaag aattttacta cgaattctgc agaaaggctt
     4441 acgaattttg caaaatgaca cagagaaaat ttttacttat atactaaggg tgggatcaag
     4501 gtaaagtatt atgtattgga acataatgtt aaaatcctaa ctttatcgta tcaggaggta
     4561 attacaatga cctatcgtaa attaaacttc gatgaattaa gcaaggtttc tggtggatgg
     4621 agtctatctt cacaggttaa tgaactagtt aaagatgttg ttaattcctt gaacaaatgg
     4681 gctcaatctt gctacgcagg ctataaagat agtccatttc actaatagtt tataacttaa
     4741 tgattatgaa atttaaccac gatttttaca ccaattttga tttttatatc tatattatag
     4801 ttacattttt ctgggtctta gcaattccca aggcaagtaa catttatgaa acaattatat
     4861 gtatagcttg cacaatcatt ggtatttttg cggctctacg aattttattt aaaaataaat
     4921 agtatcttat aagaatataa agcccagaat cattattaat tttggacttt atttctttgt
     4981 ctaattagaa agcaaggtga atgaaaatca attacccata ttatgtagcc caagttgatg
     5041 aagcagattg tggaatcgct tccttagcaa tgattctccg caattttggg tctatttatc
     5101 caatcgcaaa attacgtgat ctagcccgaa caactaagca aggaactact gccttaggat
     5161 tattaaaagc agcaaagcat cttggattag acgttattcc cattcaagca gatctatcat
     5221 tgtttgatga tcctgaaatt acttacccat tgattgcgca tgtgattaag gatgatttac
     5281 ttcattactg tgtcgttttt aaggctgatc aagattacat ctatgtagct gatccagatc
     5341 ctgctacgaa agtacaaaaa atgactcggg atgaatttgg tcgtttatgg tcaggtgtaa
     5401 gtttactttt ttcgcctgct aagggatata cgccacaaaa agaaccttta gctggattaa
     5461 tgacgatgtt tcgacaatta actaattata aaaaagatat atcaggaatt gtcattgcgg
     5521 cattattaat taccttcatc agcatcgtcg gttcatacta tctccaatta attattgatc
     5581 ggtttattcc ctcgaaaagt attaatggct tagcgattct tgctggtagt ttgttagtag
     5641 tttatgtgtt taattctctt tttaattatc tgcgagatgt tctcttgact aggctggatc
     5701 aaaaactaac gtcacaaata agtcttagat atattcacca tgtttatcgt ttaccgatga
     5761 gatttttctc cacaagaaaa acgggggaaa taacttcgcg gtttaatgac attaataaga
     5821 ttattgatgc tttatcaagc actattattt caatgttctt agatgttggc gtgatggtga
     5881 ttattggcca tgttctcttc ttgtatgatc ggtcattatt tttaactaca attagtacca
     5941 ttccgattta tgtcattatc atttatgcct ttaataagcg ttttgctaaa cttgatcagg
     6001 aacagatgga aagtaatgct caattaagtt ctgacattat tgaggattta aaaggcgtag
     6061 agacattgaa agtgctgcaa cttgaaaata tccgttataa aaatgttgaa aaacaatttg
     6121 cggatttctt acgaaagaat ctaacatatg tcaaaactaa atcttttcag gatgcgatta
     6181 aaatgtggat tcaatacggt ttagtaacaa tcattctttt tcaaggagca gttttagtaa
     6241 ttcagggtcg cttaagtatt ggaatattga tggcctttaa tgcattattg gcctttttta
     6301 tcagtccatt acaaaatatt attaatcttc aacctaaact ccaagaagct aaagtagcga
     6361 ataatcgatt aaatgaagtg ctgtaagttg acactgaaaa gtctgataca aattctcagg
     6421 atcaagcaga tttggtaggt ccgataaaca ttcaacatgt tgattattca tatgaatata
     6481 gtcgcccaat tttacaagat atcaatcttc aaattggttg taatgacaaa ttggcaattg
     6541 tagggttgag cggttctggt aaatcgacct tggcaaagtt gttagttggt ttttatttac
     6601 ccactcaagg gcagatagaa tttaatcagc ataaaacaac aaagattaat ctttgcgata
     6661 ttagacaata tgtacattac ttacctcaat cgccacaatt attttcggga acaatcaaag
     6721 ataacttgct aatgggacta gaccatgaag tatccgctga agaaatcgat aatgcatgta
     6781 aattggcatt aatctataat gatattcaag agatgccttt aaaatatgaa acaaaactag
     6841 atgaagaagc aactgcatta tctggtggtc aaaaacaacg cttgacgatt gcacgagcac
     6901 tcctaacttc tgcgcatgtt ttaattttcg atgaatcaac aagtagctta gatccaatta
     6961 ctgaaaaaag aatcgttgag aatttgcttg aaattgaaga ccgcacaatg atttttattg
     7021 cccaccgtct ttcgattgct aagaaagtca ataaagtggt agtaatgcgc gacggaaaaa
     7081 tcattgaaca gggtactcac caggaacttt tgaatcatca tcaagaatac tataatttgt
     7141 ggaatgcata aaagaggctg ggagaaaact tttgttttct ctcagcccca actacttgtt
     7201 atgaacaata gaaagataac gtggaaaata accacaaggc tcgagtctaa gtacgaacga
     7261 taatcagccc gtgccgtgct aatcatcgtc ctagcttagc caaccgcctt gtcgaggagg
     7321 ttatttccca ctctcttttt cagtctttat taaacataat tgcgagcatc gaaccgatag
     7381 taaaaattat aaagaagata catagtagtg actcatctaa tggcagcgaa ccatctgaaa
     7441 atggtgcaat ccagagaaac aaaagtaata agtatatata aaagaaacca tcccgccaaa
     7501 agtccttatt gaaatgaatt ttcattagtt ctccccctaa gacagtatgt gtaccttatt
     7561 ataatgaaag atctaattta aaggacactt tgcaaaattc gttaagtttc ttgcagaatt
     7621 cgtataggtt aactatttag aaagggactg tgacataagc gaagttactt tcataaaaaa
     7681 acaaatggcg cagtacacca atggcctcca acgcccggta aaaccgaatg ttggaggcct
     7741 attgttgctt gcgggggctc gaaaacgaag tcacgagtga cttctgtctc gctccctttt
     7801 caactaatca acttttacaa atccatcttg aacaaatttc gttccgtagg tcagagtgtt
     7861 ttccacggga cactttgcgg caacgtcagc gagaaacttc ttaatgtctt catcagactc
     7921 gttgctgcgt aggtgtggtt ggtaacggat ctcagtaaac ttacgaacat tcttgccatc
     7981 agcaacgtct tcacgaccaa gatcaccctc gattgttacc caaaaagctt gtaaatcaaa
     8041 gttacgcttt ttagctaatg cttgggcagt gattgcctgg caggcaccaa atgatgcaag
     8101 gagaatttct actggattca tccccgtatt agtactttct ggttcatcaa aggtaatttc
     8161 aaaaccacgg gtacctgctg aaacttgcat ccccgttgtt gtcttagttg ctgttacttt
     8221 atatttactc ataaccgtgc cctcctttaa tacccatagt gtaatcgaga cgatactttt
     8281 ggtcaatgag ggtgctcaat tataaggtga tttcatgtgg tgattttcct ccattaagga
     8341 ttgtcatcac atcatcaagt gaaatatcca ccatattttt gactgctaaa ttagtaaaga
     8401 aggcaatgtg gggagtaaga atgacattat ccatttcgtg taattcttta acaaggggct
     8461 gatcatcaag tcctttttct cggcggtccg cagctgcaac tgtttcttca ccttcaaagg
     8521 tatcaagggc ggccgcggcg atttcaccag cttttaatgc tgtgacgagg tcagctgtat
     8581 taacgactgg accacgacta gcattgacca aaccagcagt tggtttcatc attgcaaagt
     8641 cgttagcagt caacaatcct ttggaagctg ggtttaaatc gacgtggaga ctaacaacat
     8701 cggcttgctt tagtaattct tctttagaaa cgaactggac aattctatcg aggtcagtgc
     8761 gcggattcgt gtcatatcct agaacggtag cacctaatgc atgaagaagt tttgccaggg
     8821 ttccgccaat gcgtccaaca ccaataatcc caatcgtggc agtatgaatt tccgttgatt
     8881 gttcgtcgct aaaccagcgg aagtcatttt cggcgacttg gtggtcaaag cggtaagttt
     8941 tccgaagcaa ccggaaaatc tgcattaatg caaactcggc gacactccgc ggcgaatatg
     9001 ctggtacatt ggtcacgact aggtcatttt cgttagcctt tttgatgtcg accatgtcaa
     9061 atccagctgt ccgcgttgca atttgtttga gcccattggt atggagcttt tcataaatat
     9121 cggctggaac tttactgcgt tgctgaatta cgagtccatc aacatcggca gttaattcaa
     9181 cagcatcgtc aatcaatttc ggcgttgtga tgatttcgat attgtgttct tttgcgtatt
     9241 cgttaatggc ggtttgttca tcgtcccgca cactagtcat caagattttt gtcatgttaa
     9301 ttctccttat taatgaagga tgcaatgtta tcaagagctc cggttaaatt ttccatactg
     9361 gtggcgtaac taattcgaac atatccttgg cccccagctc caaagaagga accaggaatc
     9421 acagcaactt ttccttcatt ggcaagatct gtcgcaaatt taaggtcatc attaccatat
     9481 tgtttaggaa tcttggcaaa aacgtagaag gctccttgag gattaatcag ctcgaaccct
     9541 aatttttgga ggctattaac aacaaagtct cgtcgttgct cataggcatc tttcatttct
     9601 tgagtagctg tttttccttc gtcagtacca aatgcggcta ctgcagcggc cattgctgga
     9661 ttagaagcag cagttactaa catcgcgtga atggcactga ctgctttcat caattcttgc
     9721 ggcccagcga taaaaccaat tcggtaacca gtcattgcat gtgactttga ggcaccattt
     9781 aaaattagcg tttgttcggg gatgtaatta gcgattgaag tatgagtagc tccgtaaaca
     9841 agttccgagt aaatttcatc tgcaattaca atcaggttag ttgatttaac tgtatcggct
     9901 agtgctttaa tttggtcttg ggtgtaagta acaccagttg ggttggaggg gtagttaaga
     9961 actagtcctt ttgcgttagg atgttcttct agtacgcttt ggagtcttgc gggtgtgaga
    10021 acaaaatcat cgctgcttgt atcaacttcg atcggaatcc cacccagaat ctttgtgaca
    10081 gccatgtaga aggggaaagt tggagttgga atgataattt cgtcgccagg attaataata
    10141 gtagaaagag aagcgaaaat tccctctgtt gcaccaactg taacagcaat ttcgttttcc
    10201 ggatcgtatt ccagctcgta acgatcttgc atgaagtgag cgattgcttg gcgtagtgct
    10261 aaggtcccat ttcccggagc atagtgtgaa tcattggcat tgatgctatc gattgcggcc
    10321 tgcttcattg cggctggcac attaaagtct ggttcaccta atgttagttt aatgatgcca
    10381 gggattgcgc tggcttggta atcaaattcg cggatcccgc caggagtgag tttagcgaaa
    10441 ttattgttaa gacgattaag aatttctttt ttagtagttg gcatgataaa ttcctcctat
    10501 ataatatgta gatttagaaa aaagaagccc tgaatgctat aggaaaaaca tccagggctt
    10561 cttgatcaga ttggaatgag tataaaagag gctctcggat gtttgggggt catccgggaa
    10621 catcacaatg ataaaatcac tgctggttag cggacggtaa tcgcgctaaa ccagaagaca
    10681 tacgcttgat tcaagtgaat tgtcgcagtg ctcatcattg tgtcctcctt ttgattaact
    10741 gattattaat aattctaatt attttttaat ttttgtcaag agttgattga gaaaaactat
    10801 taattacaaa attatttatt gatgacaaat gtaaatataa taaagtgtga aaatgtttgt
    10861 gattattagt tcgcctttaa tttaatatta aatttatatt ctacaatttt ttttattttt
    10921 ttcgtgtctt ttttgttgtc ttactccaca aatgtgatat aatattaatc gtaaaggaag
    10981 tgggtagcaa tgcggatcga catcaaacat tatttggaag ttaaccactt gactatttat
    11041 caagtttcca agtgttccgg ttacggctac acgactttac acaaatcgtt taacaaacca
    11101 cagtctagtt cgacctcgct taacctgcgt gatcttgatg ccttggctcg cgctcaggac
    11161 aagagcatgt gggaggtcct taaagaacta gaagagcatt acctcgaatg agattgtggc
    11221 tttgctgtag ccacaggaag ttaaatgcgt taacttttga cttctagaat acttagacta
    11281 cgaaacttag aaaacaaaat attatattta attgaggagg gattgcatat ggctcaaaac
    11341 ccaatgaatc catttgacaa cgacatgaat gacatcttta atcaat
//
