# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Lactobacillus_reuteri/1.contigAnn/FFN/A00000301.ffn --translate --temp_dir Lactobacillus_reuteri/4.eggNOG_mapper --output_dir Lactobacillus_reuteri/4.eggNOG_mapper --output A00000301 --cpu 36 --keep_mapping_files -m diamond # time: Mon Jul 4 03:25:30 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. LEHHPAIP_00001 349123.Lreu23DRAFT_4541 4.3e-13 79.3 Lactobacillaceae Bacteria 1U6Y4@1239,29PR7@1,30APF@2,3F8PS@33958,4IGSA@91061 NA|NA|NA LEHHPAIP_00002 557436.Lreu_1599 1.9e-206 724.9 Lactobacillaceae cytX ko:K03457 ko00000 2.A.39 Bacteria 1TTBN@1239,3F4YG@33958,4HA3B@91061,COG1457@1,COG1457@2 NA|NA|NA U Belongs to the purine-cytosine permease (2.A.39) family LEHHPAIP_00003 525309.HMPREF0494_0944 5.7e-85 320.9 Lactobacillaceae ltrA Bacteria 1VAA8@1239,3F523@33958,4HMPC@91061,COG4292@1,COG4292@2 NA|NA|NA S Bacterial low temperature requirement A protein (LtrA) LEHHPAIP_00005 272626.lin0472 4.9e-80 305.4 Listeriaceae Bacteria 1TR5V@1239,26JT5@186820,4HDF3@91061,COG3835@1,COG3835@2 NA|NA|NA KT Purine catabolism regulatory protein-like family LEHHPAIP_00006 1423732.BALS01000017_gene1768 5.5e-154 550.8 Bacilli ko:K10974 ko00000,ko02000 2.A.39.1 Bacteria 1TTBN@1239,4HD25@91061,COG1457@1,COG1457@2 NA|NA|NA F Permease for cytosine/purines, uracil, thiamine, allantoin LEHHPAIP_00007 543734.LCABL_22670 5.2e-153 547.4 Lactobacillaceae ko:K09703 ko00000 Bacteria 1TR39@1239,3F5F2@33958,4HC1C@91061,COG3535@1,COG3535@2 NA|NA|NA S Protein of unknown function (DUF917) LEHHPAIP_00008 1423732.BALS01000017_gene1766 1.8e-183 649.0 Lactobacillaceae apc3 3.5.2.9 ko:K01469 ko00480,map00480 R00251 RC00553 ko00000,ko00001,ko01000 Bacteria 1TQVB@1239,3F4TR@33958,4HB8X@91061,COG0145@1,COG0145@2 NA|NA|NA EQ Hydantoinase/oxoprolinase N-terminal region LEHHPAIP_00009 1071400.LBUCD034_0440 2.7e-236 824.3 Lactobacillaceae ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 1VRWM@1239,3FBC3@33958,4HTJK@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein LEHHPAIP_00010 525309.HMPREF0494_1093 5.9e-11 74.3 Lactobacillaceae Bacteria 1U842@1239,2AIKA@1,3192G@2,3FAI4@33958,4II1H@91061 NA|NA|NA LEHHPAIP_00013 1114972.AUAW01000039_gene16 1.6e-85 323.6 Lactobacillaceae Bacteria 1UI5D@1239,3FBS7@33958,4ISEB@91061,COG2433@1,COG2433@2 NA|NA|NA S MobA/MobL family LEHHPAIP_00017 557436.Lreu_0260 1.1e-113 416.0 Lactobacillaceae Bacteria 1TR5G@1239,3F3JY@33958,4H9ZA@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain LEHHPAIP_00018 557436.Lreu_0261 1.3e-102 379.0 Lactobacillaceae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1V3NB@1239,3F3VZ@33958,4HH2Z@91061,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis LEHHPAIP_00019 557436.Lreu_0262 0.0 2282.7 Lactobacillaceae mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPF1@1239,3F4KU@33958,4H9NB@91061,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site LEHHPAIP_00020 349123.Lreu23DRAFT_5130 2.1e-39 167.9 Lactobacillaceae yabO GO:0008150,GO:0040007 Bacteria 1VEI5@1239,3F7JX@33958,4HKJJ@91061,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein LEHHPAIP_00021 349123.Lreu23DRAFT_5131 5.6e-56 223.4 Lactobacillaceae divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 1VKC5@1239,3F76Z@33958,4HR53@91061,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator LEHHPAIP_00022 349123.Lreu23DRAFT_5132 9.8e-67 259.6 Lactobacillaceae yabR ko:K07570,ko:K07571 ko00000 Bacteria 1V6FE@1239,3F6HV@33958,4HIKM@91061,COG1098@1,COG1098@2 NA|NA|NA J RNA binding LEHHPAIP_00023 557436.Lreu_0266 1.2e-250 872.1 Lactobacillaceae tilS 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPXP@1239,3F4GY@33958,4H9ZM@91061,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine LEHHPAIP_00024 349123.Lreu23DRAFT_5134 1.3e-96 359.0 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F56C@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family LEHHPAIP_00025 349123.Lreu23DRAFT_5135 0.0 1205.7 Lactobacillaceae ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPTV@1239,3F49Z@33958,4HAJB@91061,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins LEHHPAIP_00026 349123.Lreu23DRAFT_5136 2.6e-169 601.3 Lactobacillaceae hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1TRCH@1239,3F42B@33958,4HAFR@91061,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress LEHHPAIP_00027 349123.Lreu23DRAFT_5137 5.4e-189 666.8 Lactobacillaceae dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4C6@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines LEHHPAIP_00028 557436.Lreu_0271 2.8e-290 1003.8 Lactobacillaceae lysS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP2P@1239,3F439@33958,4H9X4@91061,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family LEHHPAIP_00029 349123.Lreu23DRAFT_3824 9.4e-118 429.5 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase LEHHPAIP_00030 349123.Lreu23DRAFT_3825 3e-156 557.8 Lactobacillaceae rssA Bacteria 1TQ9W@1239,3F52H@33958,4HCHJ@91061,COG4667@1,COG4667@2 NA|NA|NA S Phospholipase, patatin family LEHHPAIP_00031 349123.Lreu23DRAFT_3826 1.6e-53 216.5 Lactobacillaceae sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9,3.2.1.26 ko:K00692,ko:K01193,ko:K20811 ko00052,ko00500,ko01100,ko02020,map00052,map00500,map01100,map02020 R00801,R00802,R02410,R03635,R03921,R04194,R05140,R06088 RC00028,RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 GH32,GH68 Bacteria 1TR8C@1239,3F5DC@33958,4HBYU@91061,COG1621@1,COG1621@2,COG4932@1,COG4932@2 NA|NA|NA M Levansucrase/Invertase LEHHPAIP_00032 257314.LJ_0913 6.7e-164 583.6 Lactobacillaceae sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9,3.2.1.26 ko:K00692,ko:K01193,ko:K20811 ko00052,ko00500,ko01100,ko02020,map00052,map00500,map01100,map02020 R00801,R00802,R02410,R03635,R03921,R04194,R05140,R06088 RC00028,RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 GH32,GH68 Bacteria 1TR8C@1239,3F5DC@33958,4HBYU@91061,COG1621@1,COG1621@2 NA|NA|NA M Levansucrase/Invertase LEHHPAIP_00033 349123.Lreu23DRAFT_3826 5.8e-10 70.5 Lactobacillaceae sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9,3.2.1.26 ko:K00692,ko:K01193,ko:K20811 ko00052,ko00500,ko01100,ko02020,map00052,map00500,map01100,map02020 R00801,R00802,R02410,R03635,R03921,R04194,R05140,R06088 RC00028,RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 GH32,GH68 Bacteria 1TR8C@1239,3F5DC@33958,4HBYU@91061,COG1621@1,COG1621@2,COG4932@1,COG4932@2 NA|NA|NA M Levansucrase/Invertase LEHHPAIP_00034 557436.Lreu_0994 1.3e-201 708.8 Lactobacillaceae xerS GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K04763 ko00000,ko03036 Bacteria 1V0KQ@1239,3FBHW@33958,4HDPQ@91061,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_00036 349123.Lreu23DRAFT_3831 8e-70 269.6 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V6RB@1239,3FCD4@33958,4HJS6@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs LEHHPAIP_00037 349123.Lreu23DRAFT_3832 1.2e-76 292.4 Lactobacillaceae marR Bacteria 1VDIT@1239,3F6SX@33958,4HNFP@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family LEHHPAIP_00038 557436.Lreu_0991 7.9e-169 599.7 Lactobacillaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,3F3XP@33958,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids LEHHPAIP_00039 557436.Lreu_0990 1.4e-32 145.2 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VGIY@1239,3F7ZJ@33958,4HP0V@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis LEHHPAIP_00040 557436.Lreu_0989 2.9e-152 544.7 Lactobacillaceae fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPB7@1239,3F3W9@33958,4HBCU@91061,COG0331@1,COG0331@2 NA|NA|NA I Malonyl CoA-acyl carrier protein transacylase LEHHPAIP_00041 557436.Lreu_0988 1.2e-124 452.6 Lactobacillaceae Bacteria 1TP76@1239,3F4RI@33958,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase LEHHPAIP_00042 557436.Lreu_0987 4.1e-223 780.4 Lactobacillaceae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPA7@1239,3F51H@33958,4H9SD@91061,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP LEHHPAIP_00043 557436.Lreu_0986 2.9e-73 281.2 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VAB7@1239,3F7M1@33958,4HKCS@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA LEHHPAIP_00044 557436.Lreu_0985 8.6e-75 286.2 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V6EX@1239,3F5EE@33958,4HGX1@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs LEHHPAIP_00045 557436.Lreu_0984 7e-256 889.4 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit LEHHPAIP_00046 557436.Lreu_0983 4.2e-142 510.8 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F3T6@33958,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA LEHHPAIP_00047 557436.Lreu_0982 9.2e-136 489.6 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,3F496@33958,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I alpha subunit LEHHPAIP_00048 557436.Lreu_0981 4.3e-130 470.7 Lactobacillaceae fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPVD@1239,3F4AQ@33958,4H9YN@91061,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH LEHHPAIP_00075 324831.LGAS_0123 2.1e-24 119.0 Lactobacillaceae Bacteria 1U5CK@1239,2ACE2@1,311ZJ@2,3F5IZ@33958,4IF3R@91061 NA|NA|NA LEHHPAIP_00076 557436.Lreu_1023 9.5e-59 232.6 Lactobacillaceae Bacteria 1VQ4B@1239,2A8RI@1,30XU8@2,3F4H8@33958,4IJHJ@91061 NA|NA|NA LEHHPAIP_00077 349123.Lreu23DRAFT_3783 1.3e-70 272.3 Lactobacillaceae Bacteria 1VQ4B@1239,2A8RI@1,30XU8@2,3F4H8@33958,4IJHJ@91061 NA|NA|NA LEHHPAIP_00078 349123.Lreu23DRAFT_3782 9.3e-32 142.5 Lactobacillaceae Bacteria 1TUPQ@1239,2C0IE@1,2Z7YA@2,3F4HC@33958,4IEVE@91061 NA|NA|NA LEHHPAIP_00079 557436.Lreu_1025 9.8e-152 542.7 Lactobacillaceae 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1VDCB@1239,3F49A@33958,4HKSC@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family LEHHPAIP_00080 557436.Lreu_1026 4.7e-123 447.2 Lactobacillaceae nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP10@1239,3F3NR@33958,4HAG4@91061,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion LEHHPAIP_00081 349123.Lreu23DRAFT_3780 2e-100 371.7 Lactobacillaceae fic ko:K04095 ko00000,ko03036 Bacteria 1VK13@1239,3F711@33958,4IQYB@91061,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family LEHHPAIP_00082 349123.Lreu23DRAFT_3779 2.8e-70 271.2 Lactobacillaceae Bacteria 1U6P4@1239,2AR8Z@1,31GIU@2,3F88G@33958,4IGG4@91061 NA|NA|NA LEHHPAIP_00083 349123.Lreu23DRAFT_3778 0.0 1398.3 Lactobacillaceae XK27_00340 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3F4S2@33958,4HB9S@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family LEHHPAIP_00084 557436.Lreu_1030 2.1e-88 332.0 Lactobacillaceae ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1V8AM@1239,3F813@33958,4IPMQ@91061,COG1525@1,COG1525@2 NA|NA|NA L nuclease LEHHPAIP_00085 349123.Lreu23DRAFT_3403 2.7e-39 167.5 Lactobacillaceae Bacteria 1U6K4@1239,29PH0@1,30AF5@2,3F82R@33958,4IGCT@91061 NA|NA|NA LEHHPAIP_00086 557436.Lreu_0357 0.0 1171.8 Lactobacillaceae ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 Bacteria 1TQE1@1239,3F44Y@33958,4HAZH@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00087 557436.Lreu_0356 4.5e-302 1043.1 Lactobacillaceae ybeC Bacteria 1TPJH@1239,3FCAM@33958,4HUE6@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00088 557436.Lreu_0355 2e-80 305.1 Lactobacillaceae ko:K19055 ko00000,ko01000,ko03016 Bacteria 1V29H@1239,3F6ZD@33958,4HP8F@91061,COG3760@1,COG3760@2 NA|NA|NA S Aminoacyl-tRNA editing domain LEHHPAIP_00089 557436.Lreu_0354 5.5e-292 1009.6 Lactobacillaceae groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1TP1T@1239,3F3MM@33958,4HA38@91061,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions LEHHPAIP_00090 349123.Lreu23DRAFT_3398 1.1e-43 182.2 Lactobacillaceae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1V9ZM@1239,3F7CZ@33958,4HKEK@91061,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter LEHHPAIP_00092 349123.Lreu23DRAFT_3396 8.2e-114 416.4 Lactobacillaceae rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,3F40G@33958,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state LEHHPAIP_00093 557436.Lreu_0351 0.0 1075.5 Lactobacillaceae uup ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein LEHHPAIP_00094 349123.Lreu23DRAFT_3394 1.6e-182 645.2 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid LEHHPAIP_00095 349123.Lreu23DRAFT_3393 5.9e-227 793.1 Lactobacillaceae mtnE 2.6.1.83 ko:K08969,ko:K10206 ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230 M00034,M00527 R07396,R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQD6@1239,3F4TW@33958,4HAHQ@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase LEHHPAIP_00096 349123.Lreu23DRAFT_3392 1.6e-140 505.4 Lactobacillaceae mtnU 3.5.1.3 ko:K11206,ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 1TQDK@1239,3F4ND@33958,4HC44@91061,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase LEHHPAIP_00097 349123.Lreu23DRAFT_3391 8.4e-137 493.0 Lactobacillaceae proB GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPG6@1239,3F4E1@33958,4HA9B@91061,COG0263@1,COG0263@2 NA|NA|NA F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate LEHHPAIP_00098 349123.Lreu23DRAFT_3390 7.6e-217 759.6 Lactobacillaceae proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130 Bacteria 1TQ9V@1239,3F3W7@33958,4HB7B@91061,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate LEHHPAIP_00099 557436.Lreu_0344 2e-130 471.9 Lactobacillaceae proC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0899,iIT341.HP1158 Bacteria 1TP1E@1239,3F4SE@33958,4H9RV@91061,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline LEHHPAIP_00100 557436.Lreu_0343 2e-194 684.9 Lactobacillaceae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TQDR@1239,3F4AX@33958,4HANB@91061,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction LEHHPAIP_00101 349123.Lreu23DRAFT_3387 2e-100 371.7 Lactobacillaceae rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,3F522@33958,4HIKU@91061,COG0454@1,COG0456@2 NA|NA|NA K Ribosomal-protein-alanine acetyltransferase LEHHPAIP_00102 557436.Lreu_0341 9.5e-127 459.5 Lactobacillaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,3F3WV@33958,4HHD7@91061,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ LEHHPAIP_00104 557436.Lreu_1584 9.4e-27 125.9 Lactobacillaceae ko:K07482 ko00000 Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region LEHHPAIP_00105 575594.ACOH01000017_gene1539 1.7e-67 262.3 Lactobacillaceae ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1U59Y@1239,3F5BK@33958,4IF1G@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_00106 748671.LCRIS_00244 8.1e-149 533.9 Lactobacillaceae 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 1UHXY@1239,3F52E@33958,4ISAC@91061,COG1196@1,COG1196@2,COG3064@1,COG3064@2 NA|NA|NA M Rib/alpha-like repeat LEHHPAIP_00107 575594.ACOH01000006_gene262 5.3e-54 216.9 Lactobacillaceae ko:K08368 ko00000,ko02000 2.A.1 Bacteria 1UHPS@1239,3FBSI@33958,4IS5K@91061,COG0477@1,COG0477@2 NA|NA|NA U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family LEHHPAIP_00108 575594.ACOH01000006_gene263 3.5e-174 617.8 Lactobacillaceae Bacteria 1TRFZ@1239,3F4KN@33958,4HEZ0@91061,COG1808@1,COG1808@2 NA|NA|NA S Domain of unknown function (DUF389) LEHHPAIP_00109 575594.ACOH01000006_gene264 1e-88 332.8 Lactobacillaceae ko:K06400 ko00000 Bacteria 1TPBH@1239,3F590@33958,4IPTE@91061,COG1961@1,COG1961@2 NA|NA|NA L Recombinase LEHHPAIP_00110 324831.LGAS_1462 1.2e-68 266.2 Lactobacillaceae ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1U5BV@1239,3F5ZJ@33958,4HC81@91061,COG1475@1,COG1475@2 NA|NA|NA K DNA binding LEHHPAIP_00111 324831.LGAS_1461 1e-120 439.5 Bacteria Bacteria COG0553@1,COG0553@2 NA|NA|NA L helicase activity LEHHPAIP_00112 334390.LAF_1040 4.9e-207 726.9 Bacteria Bacteria COG0553@1,COG0553@2 NA|NA|NA L helicase activity LEHHPAIP_00114 891391.LAC30SC_02695 1.8e-55 221.9 Lactobacillaceae arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1V3JW@1239,3F6GQ@33958,4HH49@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family LEHHPAIP_00115 557436.Lreu_0786 2e-163 581.6 Lactobacillaceae ko:K07482 ko00000 Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region LEHHPAIP_00116 272621.LBA0541 0.0 1153.7 Lactobacillaceae cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3FC0Y@33958,4HT7C@91061,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase LEHHPAIP_00117 1133569.AHYZ01000062_gene1502 7.9e-35 152.5 Lactobacillaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VK5F@1239,3FBN8@33958,4IRA3@91061,COG2608@1,COG2608@2 NA|NA|NA C Heavy-metal-associated domain LEHHPAIP_00118 272621.LBA0543 1.2e-94 352.4 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VB1X@1239,3F4SN@33958,4HMJG@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family LEHHPAIP_00119 1133569.AHYZ01000062_gene1500 5.2e-113 413.7 Lactobacillaceae rcfA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3XW@1239,3F4YM@33958,4HDG1@91061,COG0664@1,COG0664@2 NA|NA|NA K Transcriptional regulator, Crp Fnr family LEHHPAIP_00120 272621.LBA0545 6.3e-113 413.3 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1F8@1239,3F4WH@33958,4HFVS@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase LEHHPAIP_00121 1133569.AHYZ01000062_gene1498 3.6e-62 244.2 Lactobacillaceae 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 iHN637.CLJU_RS14520 Bacteria 1TR3U@1239,3F6H8@33958,4HCAN@91061,COG1794@1,COG1794@2 NA|NA|NA M Asp/Glu/Hydantoin racemase LEHHPAIP_00122 272621.LBA0546 2e-22 110.9 Lactobacillaceae 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 iHN637.CLJU_RS14520 Bacteria 1TR3U@1239,3F6H8@33958,4HCAN@91061,COG1794@1,COG1794@2 NA|NA|NA M Asp/Glu/Hydantoin racemase LEHHPAIP_00123 1423814.HMPREF0549_1462 1.5e-69 268.9 Lactobacillaceae ko:K06400 ko00000 Bacteria 1TPBH@1239,3F590@33958,4IPTE@91061,COG1961@1,COG1961@2 NA|NA|NA L Recombinase LEHHPAIP_00124 1423814.HMPREF0549_1462 2.6e-67 261.2 Lactobacillaceae ko:K06400 ko00000 Bacteria 1TPBH@1239,3F590@33958,4IPTE@91061,COG1961@1,COG1961@2 NA|NA|NA L Recombinase LEHHPAIP_00125 1133569.AHYZ01000062_gene1494 1.7e-21 109.0 Bacteria Bacteria COG1961@1,COG1961@2 NA|NA|NA L recombinase activity LEHHPAIP_00126 1133569.AHYZ01000062_gene1493 4.7e-19 100.5 Lactobacillaceae Bacteria 1TPBH@1239,3F4SH@33958,4IQ08@91061,COG1961@1,COG1961@2 NA|NA|NA L Recombinase zinc beta ribbon domain LEHHPAIP_00127 324831.LGAS_1490 1.3e-68 265.8 Lactobacillaceae Bacteria 1TPBH@1239,3F4SH@33958,4IQ08@91061,COG1961@1,COG1961@2 NA|NA|NA L Recombinase zinc beta ribbon domain LEHHPAIP_00128 324831.LGAS_1489 8.2e-19 99.4 Lactobacillaceae Bacteria 1U69K@1239,2DKP9@1,30A6N@2,3F7DG@33958,4IG0R@91061 NA|NA|NA LEHHPAIP_00129 324831.LGAS_1487 2.4e-29 134.4 Lactobacillaceae Bacteria 1V3TR@1239,3F68Y@33958,4IRAT@91061,COG4824@1,COG4824@2 NA|NA|NA S Bacteriophage holin family LEHHPAIP_00130 525309.HMPREF0494_0883 7.2e-54 216.5 Lactobacillaceae Bacteria 1VBQZ@1239,3F6FJ@33958,4IFGX@91061,COG5614@1,COG5614@2 NA|NA|NA S Phage head-tail joining protein LEHHPAIP_00131 575594.ACOH01000006_gene269 1.3e-39 168.7 Lactobacillaceae Bacteria 1VETG@1239,2E3C8@1,32YBI@2,3FA1K@33958,4IS2S@91061 NA|NA|NA S Phage gp6-like head-tail connector protein LEHHPAIP_00132 324831.LGAS_1485 8.8e-172 609.8 Lactobacillaceae Bacteria 1TS6A@1239,3F4Y2@33958,4HCCS@91061,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family LEHHPAIP_00133 349123.Lreu23DRAFT_4344 1.2e-88 332.4 Lactobacillaceae tpx 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 1V474@1239,3F5VY@33958,4HFMW@91061,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides LEHHPAIP_00134 1423814.HMPREF0549_1452 1.1e-127 462.6 Lactobacillaceae 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1TST7@1239,3F54T@33958,4HEFP@91061,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F NUDIX domain LEHHPAIP_00135 1423814.HMPREF0549_1453 6.6e-257 892.9 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP LEHHPAIP_00136 1423814.HMPREF0549_1454 1.2e-102 379.0 Lactobacillaceae pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 ko:K16788 ko00000,ko02000 2.A.88.5 iSB619.SA_RS09955 Bacteria 1V1CY@1239,3F41F@33958,4HFRS@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family LEHHPAIP_00137 349123.Lreu23DRAFT_5095 3.4e-149 534.3 Lactobacillaceae lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 ko00000,ko01000 Bacteria 1TQKA@1239,3F575@33958,4HCPS@91061,COG0095@1,COG0095@2 NA|NA|NA H biotin lipoate A B protein ligase LEHHPAIP_00138 557436.Lreu_0224 1e-270 938.7 Lactobacillaceae ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 1TPVB@1239,3F442@33958,4HAX8@91061,COG1078@1,COG1078@2 NA|NA|NA S HD domain protein LEHHPAIP_00139 557436.Lreu_0223 2.1e-146 525.0 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase LEHHPAIP_00140 349123.Lreu23DRAFT_5092 1.2e-47 196.8 Lactobacillaceae Bacteria 1U5XS@1239,29P09@1,309YE@2,3F6NK@33958,4IFM1@91061 NA|NA|NA LEHHPAIP_00141 557436.Lreu_0221 4.2e-178 630.6 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3U2@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) LEHHPAIP_00142 349123.Lreu23DRAFT_5090 9.2e-240 835.9 Lactobacillaceae glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP88@1239,3F4I3@33958,4H9V5@91061,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain LEHHPAIP_00143 557436.Lreu_0219 6.9e-150 536.6 Lactobacillaceae purR 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1TPN9@1239,3F3NH@33958,4HB8I@91061,COG0503@1,COG0503@2 NA|NA|NA F pur operon repressor LEHHPAIP_00144 349123.Lreu23DRAFT_5088 1.2e-117 429.5 Lactobacillaceae znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1V0SX@1239,3FC75@33958,4HTE9@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family LEHHPAIP_00145 557436.Lreu_0217 2.2e-122 444.9 Lactobacillaceae fhuC ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1TQ68@1239,3F49M@33958,4HAZI@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter LEHHPAIP_00146 557436.Lreu_0216 1.8e-167 595.1 Lactobacillaceae znuA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FBJR@33958,4HZ7G@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family LEHHPAIP_00147 557436.Lreu_0215 3.1e-161 574.3 Lactobacillaceae ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 1TPXV@1239,3F43W@33958,4HAV8@91061,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol LEHHPAIP_00148 349123.Lreu23DRAFT_5083 6.8e-37 159.5 Lactobacillaceae veg Bacteria 1VEQM@1239,3F7D3@33958,4HKF8@91061,COG4466@1,COG4466@2 NA|NA|NA S Biofilm formation stimulator VEG LEHHPAIP_00149 349123.Lreu23DRAFT_5082 3.6e-160 570.9 Lactobacillaceae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 1TP9W@1239,3F3VC@33958,4HA4R@91061,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits LEHHPAIP_00150 557436.Lreu_0212 2.1e-97 361.7 Lactobacillaceae rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985,ko:K07476 ko00000,ko01000 Bacteria 1V3K3@1239,3F64F@33958,4HH5Y@91061,COG1658@1,COG1658@2 NA|NA|NA J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step LEHHPAIP_00151 349123.Lreu23DRAFT_5080 3.5e-154 550.8 Lactobacillaceae tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1TNY1@1239,3F3N2@33958,4HA74@91061,COG0084@1,COG0084@2 NA|NA|NA L hydrolase, TatD family LEHHPAIP_00152 349123.Lreu23DRAFT_5079 0.0 1333.2 Lactobacillaceae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPA1@1239,3F3XR@33958,4H9VC@91061,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation LEHHPAIP_00153 557436.Lreu_0209 1.2e-160 572.4 Lactobacillaceae yunF Bacteria 1TPX4@1239,3F40Y@33958,4HA0X@91061,COG1801@1,COG1801@2 NA|NA|NA F Protein of unknown function DUF72 LEHHPAIP_00155 557436.Lreu_0208 3.4e-129 467.6 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3F4WS@33958,4HC4I@91061,COG0846@1,COG0846@2 NA|NA|NA K SIR2 family LEHHPAIP_00156 557436.Lreu_0207 1.6e-177 628.6 Lactobacillaceae Bacteria 1VT7R@1239,296WI@1,2ZU5A@2,3F4R1@33958,4HVBN@91061 NA|NA|NA LEHHPAIP_00157 557436.Lreu_0206 9.1e-226 789.3 Lactobacillaceae mvaA 1.1.1.34,1.1.1.88,2.3.1.9 ko:K00021,ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081,R02082 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPNY@1239,3F3YY@33958,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family LEHHPAIP_00158 349123.Lreu23DRAFT_5073 2.1e-166 591.7 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase LEHHPAIP_00159 557436.Lreu_0204 7.7e-191 672.9 Lactobacillaceae trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPY7@1239,3F3V6@33958,4HA1K@91061,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family LEHHPAIP_00160 557436.Lreu_0203 2.1e-182 644.8 Lactobacillaceae hpaIM 2.1.1.72 ko:K00571,ko:K07319 ko00000,ko01000,ko02048 Bacteria 1UHUQ@1239,3F56H@33958,4HCEV@91061,COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family LEHHPAIP_00161 349123.Lreu23DRAFT_5070 6.3e-81 306.6 Lactobacillaceae ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 1V44G@1239,3F68C@33958,4HH8C@91061,COG0105@1,COG0105@2 NA|NA|NA F Belongs to the NDK family LEHHPAIP_00162 557436.Lreu_0201 0.0 1465.7 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase LEHHPAIP_00163 557436.Lreu_0200 2.4e-204 718.0 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family LEHHPAIP_00165 557436.Lreu_0199 4.5e-255 886.7 Lactobacillaceae gabT 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1VS6F@1239,3F569@33958,4H9M7@91061,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family LEHHPAIP_00166 557436.Lreu_0198 5.2e-265 919.8 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3FCAJ@33958,4HA32@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00167 557436.Lreu_0197 9.3e-118 429.5 Lactobacillaceae nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRAK@1239,3F42U@33958,4HATD@91061,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate LEHHPAIP_00168 557436.Lreu_0196 8.9e-41 172.6 Bacteria 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria COG3976@1,COG3976@2 NA|NA|NA S FMN binding LEHHPAIP_00169 349123.Lreu23DRAFT_5038 7.1e-220 769.6 Lactobacillaceae norA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08153,ko:K19576,ko:K19578 M00717,M00765 ko00000,ko00002,ko02000 2.A.1.2.10,2.A.1.2.70,2.A.1.2.8 Bacteria 1TS6K@1239,3F4X1@33958,4HB1V@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00170 557436.Lreu_0194 5.8e-169 600.1 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily LEHHPAIP_00171 557436.Lreu_0193 6.3e-154 550.1 Lactobacillaceae metQ1 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family LEHHPAIP_00172 349123.Lreu23DRAFT_5035 4.7e-191 673.7 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system LEHHPAIP_00173 349123.Lreu23DRAFT_5034 3.1e-103 381.3 Lactobacillaceae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease LEHHPAIP_00174 349123.Lreu23DRAFT_5033 1.2e-213 748.8 Lactobacillaceae argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase LEHHPAIP_00175 349123.Lreu23DRAFT_5032 6e-189 666.8 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281 ko00000 2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F587@33958,4HD2H@91061,COG0038@1,COG0038@2 NA|NA|NA P chloride LEHHPAIP_00176 349123.Lreu23DRAFT_4366 8.8e-215 752.7 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family LEHHPAIP_00177 349123.Lreu23DRAFT_5096 3.4e-58 230.7 Lactobacillaceae ko:K07491 ko00000 Bacteria 1V3YY@1239,3F6SB@33958,4HJZJ@91061,COG1943@1,COG1943@2 NA|NA|NA L PFAM transposase IS200-family protein LEHHPAIP_00178 1423734.JCM14202_2833 7.4e-25 119.0 Lactobacillaceae ltrA_1 Bacteria 1TP9A@1239,3F4TJ@33958,4H9NW@91061,COG3344@1,COG3344@2 NA|NA|NA L PFAM RNA-directed DNA polymerase (Reverse transcriptase) LEHHPAIP_00179 944562.HMPREF9102_1889 7.1e-84 316.6 Lactobacillaceae panE1 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid LEHHPAIP_00180 525309.HMPREF0494_0657 2.4e-211 741.5 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid LEHHPAIP_00181 1423814.HMPREF0549_1573 2.6e-176 624.8 Bacilli Bacteria 1VAIE@1239,4HZG7@91061,COG4127@1,COG4127@2 NA|NA|NA S FRG LEHHPAIP_00182 557436.Lreu_0364 4.5e-97 360.5 Lactobacillaceae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1V1D5@1239,3F40M@33958,4HFX9@91061,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase LEHHPAIP_00183 557436.Lreu_0363 6e-115 420.2 Lactobacillaceae comFC ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 1V73S@1239,3F714@33958,4HJ6R@91061,COG1040@1,COG1040@2 NA|NA|NA S Competence protein LEHHPAIP_00184 557436.Lreu_0362 3.6e-249 867.1 Lactobacillaceae comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K02240 M00429 ko00000,ko00002,ko02044 3.A.11.1 Bacteria 1TPZE@1239,3F3TQ@33958,4HB00@91061,COG4098@1,COG4098@2 NA|NA|NA L Helicase C-terminal domain protein LEHHPAIP_00185 349123.Lreu23DRAFT_3407 2.1e-106 391.7 Lactobacillaceae yvyE 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1V6MQ@1239,3F3SQ@33958,4HBIT@91061,COG1739@1,COG1739@2 NA|NA|NA S YigZ family LEHHPAIP_00186 349123.Lreu23DRAFT_3222 2.2e-44 184.5 Lactobacillaceae Bacteria 1U6Q7@1239,2CE48@1,2ZYCQ@2,3F8AG@33958,4IGHA@91061 NA|NA|NA LEHHPAIP_00187 557436.Lreu_0868 3.1e-57 228.0 Lactobacillaceae yhaI Bacteria 1VN88@1239,3F8S0@33958,4HSH3@91061,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) LEHHPAIP_00188 1423814.HMPREF0549_0260 6.2e-140 503.4 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase LEHHPAIP_00189 349123.Lreu23DRAFT_3224 0.0 2058.9 Lactobacillaceae hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1TP7S@1239,3F50Q@33958,4HB5A@91061,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification LEHHPAIP_00190 349123.Lreu23DRAFT_3225 1e-280 972.2 Lactobacillaceae hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1TPGZ@1239,3F4HM@33958,4HA1J@91061,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification system LEHHPAIP_00191 1139996.OMQ_00037 1.6e-46 193.7 Enterococcaceae 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,4B379@81852,4HFAV@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain LEHHPAIP_00192 349123.Lreu23DRAFT_3227 8.9e-178 629.4 Lactobacillaceae Bacteria 1TPE1@1239,3FC9T@33958,4HDHJ@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_00193 1158614.I592_03783 9.1e-55 221.1 Enterococcaceae hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,4B379@81852,4HFAV@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain LEHHPAIP_00194 349123.Lreu23DRAFT_3229 3.3e-161 574.3 Lactobacillaceae ko:K07448 ko00000,ko02048 Bacteria 1V7W8@1239,3F4T4@33958,4HHU7@91061,COG1715@1,COG1715@2 NA|NA|NA L restriction endonuclease LEHHPAIP_00195 585524.HMPREF0493_1681 2e-89 335.9 Lactobacillaceae mrr GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700 ko:K07448 ko00000,ko02048 Bacteria 1V1TA@1239,3F5UV@33958,4HC3T@91061,COG1715@1,COG1715@2 NA|NA|NA L restriction endonuclease LEHHPAIP_00196 557436.Lreu_0876 0.0 1494.9 Lactobacillaceae Bacteria 1UJK2@1239,3FBV9@33958,4HWPF@91061,COG3886@1,COG3886@2 NA|NA|NA L PLD-like domain LEHHPAIP_00198 349123.Lreu23DRAFT_4611 2e-09 67.0 Lactobacillaceae Bacteria 1TR1J@1239,3FC9P@33958,4HHQ8@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain LEHHPAIP_00199 557436.Lreu_1659 6.2e-114 416.8 Lactobacillaceae Bacteria 1TR1J@1239,3FC9P@33958,4HHQ8@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain LEHHPAIP_00200 557436.Lreu_1660 3.3e-133 481.1 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VR9G@1239,3F3TR@33958,4HV4W@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein LEHHPAIP_00201 557436.Lreu_1661 7.9e-97 359.8 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V39N@1239,3F4QM@33958,4HF32@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component LEHHPAIP_00202 557436.Lreu_1662 4.4e-250 870.2 Lactobacillaceae cbiO1 ko:K05776,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00189,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1UI2R@1239,3F3WM@33958,4ISG8@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein LEHHPAIP_00203 557436.Lreu_1663 6.6e-111 406.8 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V679@1239,3FBEQ@33958,4HFRQ@91061,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein LEHHPAIP_00204 557436.Lreu_1664 1.6e-52 211.8 Lactobacillaceae yvlA Bacteria 1VIUB@1239,2DZIG@1,32VBI@2,3F7EN@33958,4HRZP@91061 NA|NA|NA LEHHPAIP_00205 349123.Lreu23DRAFT_4617 0.0 1206.8 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter LEHHPAIP_00206 349123.Lreu23DRAFT_4618 6.4e-52 209.9 Lactobacillaceae ypaA ko:K08987 ko00000 Bacteria 1VAVU@1239,3F7NA@33958,4HQHN@91061,COG3759@1,COG3759@2 NA|NA|NA S Protein of unknown function (DUF1304) LEHHPAIP_00207 349123.Lreu23DRAFT_4619 1.7e-187 661.8 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta LEHHPAIP_00208 349123.Lreu23DRAFT_4620 1e-72 279.3 Lactobacillaceae Bacteria 1VEC4@1239,3F654@33958,4HM2F@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_00209 557436.Lreu_1669 3.2e-158 564.3 Lactobacillaceae Bacteria 1VQQ8@1239,2E39Q@1,32Y99@2,3F4UX@33958,4HRY1@91061 NA|NA|NA LEHHPAIP_00210 349123.Lreu23DRAFT_4622 4.1e-87 327.4 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1TZGF@1239,3FC43@33958,4HEDQ@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase LEHHPAIP_00211 557436.Lreu_1670 4.4e-23 113.2 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1TZGF@1239,3FC43@33958,4HEDQ@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase LEHHPAIP_00212 557436.Lreu_1671 4.2e-256 890.2 Lactobacillaceae ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 Bacteria 1TQ10@1239,3FCCF@33958,4HF7Z@91061,COG3775@1,COG3775@2 NA|NA|NA G PTS system Galactitol-specific IIC component LEHHPAIP_00213 349123.Lreu23DRAFT_4624 1.7e-210 738.4 Lactobacillaceae Bacteria 1TRNU@1239,3FCA6@33958,4HCSX@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00214 349123.Lreu23DRAFT_4625 3.9e-135 487.6 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPJE@1239,3F58G@33958,4HB5U@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter LEHHPAIP_00215 557436.Lreu_1674 8.2e-115 419.9 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VRGN@1239,2E0PZ@1,32W8Q@2,3F72X@33958,4HWS3@91061 NA|NA|NA LEHHPAIP_00216 349123.Lreu23DRAFT_3436 8.8e-15 85.1 Lactobacillaceae Bacteria 1U6K5@1239,29PH2@1,30AF7@2,3F82T@33958,4IGCV@91061 NA|NA|NA LEHHPAIP_00218 349123.Lreu23DRAFT_3434 1.5e-169 602.1 Lactobacillaceae whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 ko:K09762 ko00000 Bacteria 1TP2X@1239,3F4AB@33958,4HB4H@91061,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation LEHHPAIP_00219 349123.Lreu23DRAFT_3433 2.1e-185 654.8 Lactobacillaceae ybhK Bacteria 1TPNV@1239,3F4D5@33958,4HA0Z@91061,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions LEHHPAIP_00220 557436.Lreu_0386 1.2e-160 572.4 Lactobacillaceae rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1TPS4@1239,3F4NY@33958,4H9KM@91061,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities LEHHPAIP_00221 557436.Lreu_0385 2.7e-244 850.9 Lactobacillaceae steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00222 349123.Lreu23DRAFT_3430 0.0 1884.4 Lactobacillaceae uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPIJ@1239,3F4TZ@33958,4HAW9@91061,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate LEHHPAIP_00223 557436.Lreu_0383 0.0 1303.1 Lactobacillaceae uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,3F3XM@33958,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage LEHHPAIP_00224 891391.LAC30SC_02465 2e-13 81.6 Lactobacillaceae Bacteria 1U6JA@1239,29PGB@1,30AEG@2,3F80W@33958,4IGBU@91061 NA|NA|NA LEHHPAIP_00225 349123.Lreu23DRAFT_3427 5.1e-116 423.7 Lactobacillaceae yfbR ko:K07023 ko00000 Bacteria 1TSDU@1239,3F4RZ@33958,4HA8H@91061,COG1896@1,COG1896@2 NA|NA|NA S HD containing hydrolase-like enzyme LEHHPAIP_00226 557436.Lreu_0380 0.0 1151.3 Lactobacillaceae pgm GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2N@1239,3F457@33958,4HADU@91061,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain LEHHPAIP_00227 349123.Lreu23DRAFT_3425 7.2e-89 333.2 Lactobacillaceae ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria 1V3S2@1239,3F6A3@33958,4HJ0Z@91061,COG1607@1,COG1607@2 NA|NA|NA I Thioesterase superfamily LEHHPAIP_00228 557436.Lreu_0378 1.9e-161 575.1 Lactobacillaceae aatB ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQNR@1239,3F432@33958,4IETM@91061,COG0834@1,COG0834@2 NA|NA|NA ET PFAM extracellular solute-binding protein, family 3 LEHHPAIP_00229 349123.Lreu23DRAFT_3423 1.8e-204 718.4 Lactobacillaceae argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase LEHHPAIP_00230 557436.Lreu_0376 8.6e-173 612.8 Lactobacillaceae trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F411@33958,4HA4N@91061,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family LEHHPAIP_00231 557436.Lreu_0375 2.7e-168 597.8 Lactobacillaceae lutA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K18928 ko00000 iEC042_1314.EC042_0340,iEcSMS35_1347.EcSMS35_0338 Bacteria 1TPFC@1239,3F4GX@33958,4HAKC@91061,COG0247@1,COG0247@2 NA|NA|NA C Cysteine-rich domain LEHHPAIP_00232 557436.Lreu_0374 3.5e-293 1013.4 Lactobacillaceae lutB ko:K18929 ko00000 iSF_1195.SF0259,iSFxv_1172.SFxv_0274,iS_1188.S0280 Bacteria 1TREQ@1239,3F4IV@33958,4H9UI@91061,COG1139@1,COG1139@2 NA|NA|NA C 4Fe-4S dicluster domain LEHHPAIP_00233 557436.Lreu_0373 4.6e-137 493.8 Lactobacillaceae yrjD ko:K00782 ko00000 Bacteria 1UZAK@1239,3F4UV@33958,4HH3R@91061,COG1556@1,COG1556@2 NA|NA|NA S LUD domain LEHHPAIP_00234 349123.Lreu23DRAFT_3418 1.1e-169 602.4 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase LEHHPAIP_00235 349123.Lreu23DRAFT_3417 8.5e-182 642.9 Lactobacillaceae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQ5P@1239,3F4C8@33958,4HAXW@91061,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase LEHHPAIP_00236 557436.Lreu_0370 2.1e-154 551.6 Lactobacillaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,3F42N@33958,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins LEHHPAIP_00237 349123.Lreu23DRAFT_3415 1.7e-176 625.2 Lactobacillaceae hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1TP5Z@1239,3F3Z3@33958,4HAXR@91061,COG1493@1,COG1493@2 NA|NA|NA F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion LEHHPAIP_00238 349123.Lreu23DRAFT_3414 4.9e-52 210.3 Lactobacillaceae yvlD ko:K08972 ko00000 Bacteria 1VF4I@1239,3F7IN@33958,4HNXP@91061,COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV LEHHPAIP_00239 908339.HMPREF9265_0848 7.7e-31 139.8 Lactobacillaceae ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VKBQ@1239,3F7XD@33958,4HQZ8@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain protein LEHHPAIP_00240 557436.Lreu_0366 1.7e-187 661.8 Lactobacillaceae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1TPSB@1239,3F3SN@33958,4H9N2@91061,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA LEHHPAIP_00241 349123.Lreu23DRAFT_3411 0.0 1552.0 Lactobacillaceae secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TPEY@1239,3F4DH@33958,4HA22@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane LEHHPAIP_00242 557436.Lreu_0427 1.4e-153 548.9 Lactobacillaceae Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family LEHHPAIP_00243 557436.Lreu_0426 2.1e-171 608.2 Lactobacillaceae arcC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 Bacteria 1TP9H@1239,3F3T4@33958,4H9QD@91061,COG0549@1,COG0549@2 NA|NA|NA E Belongs to the carbamate kinase family LEHHPAIP_00244 557436.Lreu_0425 7.6e-191 672.9 Lactobacillaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 iAF1260.b0273,iECDH10B_1368.ECDH10B_0261,iECS88_1305.ECS88_4841,iHN637.CLJU_RS12430,iJO1366.b0273,iJR904.b0273,iY75_1357.Y75_RS01410 Bacteria 1TPF2@1239,3F48K@33958,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline LEHHPAIP_00245 349123.Lreu23DRAFT_3488 3.6e-154 550.8 Lactobacillaceae ko:K03413,ko:K07719 ko02020,ko02030,map02020,map02030 M00506,M00518 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 1UHR2@1239,3F61D@33958,4HIGR@91061,COG2197@1,COG2197@2 NA|NA|NA KT YcbB domain LEHHPAIP_00246 557436.Lreu_0422 3.1e-30 137.1 Lactobacillaceae xylB 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family LEHHPAIP_00248 349123.Lreu23DRAFT_3477 1e-25 122.1 Lactobacillaceae Bacteria 1U74Y@1239,2AE1U@1,313UM@2,3F8ZF@33958,4IGZM@91061 NA|NA|NA LEHHPAIP_00249 349123.Lreu23DRAFT_3476 5e-262 909.8 Lactobacillaceae pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iLJ478.TM1385 Bacteria 1TP29@1239,3F3XK@33958,4H9VI@91061,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family LEHHPAIP_00250 557436.Lreu_0419 9.6e-96 356.3 Lactobacillaceae lacA 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1V06U@1239,3FBEW@33958,4IPZB@91061,COG0110@1,COG0110@2 NA|NA|NA S Transferase hexapeptide repeat LEHHPAIP_00251 557436.Lreu_0418 4.1e-153 547.4 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport LEHHPAIP_00252 557436.Lreu_0417 5.8e-272 943.0 Lactobacillaceae yclK 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3FBSR@33958,4IS6U@91061,COG5000@1,COG5000@2,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase LEHHPAIP_00253 557436.Lreu_0416 1.6e-134 485.3 Lactobacillaceae Bacteria 1TQUQ@1239,3F3QZ@33958,4HAXP@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator LEHHPAIP_00255 349123.Lreu23DRAFT_3471 1.3e-76 292.7 Lactobacillaceae lytE Bacteria 1VA10@1239,3FC14@33958,4HMUH@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif LEHHPAIP_00256 557436.Lreu_0414 1.1e-147 529.3 Lactobacillaceae XK27_02985 Bacteria 1VUNA@1239,3FC84@33958,4HVG5@91061,COG0561@1,COG0561@2 NA|NA|NA S Cof-like hydrolase LEHHPAIP_00257 557436.Lreu_0413 1.8e-78 298.5 Lactobacillaceae Bacteria 1V6TR@1239,3F66M@33958,4HXA8@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_00258 349123.Lreu23DRAFT_3468 0.0 1205.7 Lactobacillaceae oatA Bacteria 1TPTG@1239,3F3WT@33958,4HB7R@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase LEHHPAIP_00259 349123.Lreu23DRAFT_3467 5.6e-52 209.9 Lactobacillaceae Bacteria 1VX4A@1239,2C26E@1,3424N@2,3F70Q@33958,4HXT9@91061 NA|NA|NA LEHHPAIP_00260 349123.Lreu23DRAFT_3466 0.0 1182.9 Lactobacillaceae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 1TPGU@1239,3F467@33958,4H9R4@91061,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source LEHHPAIP_00261 557436.Lreu_0409 8.5e-254 882.5 Lactobacillaceae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1TP1X@1239,3F3W5@33958,4HB16@91061,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate LEHHPAIP_00262 557436.Lreu_0408 1.7e-125 455.7 Lactobacillaceae ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 1TSIV@1239,3F41C@33958,4HD8Y@91061,COG4856@1,COG4856@2 NA|NA|NA S YbbR-like protein LEHHPAIP_00263 349123.Lreu23DRAFT_3463 5e-151 540.4 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 1TPRW@1239,3F4N3@33958,4H9XZ@91061,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria LEHHPAIP_00264 557436.Lreu_0406 3.4e-247 860.5 Lactobacillaceae fucP ko:K02429 ko00000,ko02000 2.A.1.7 Bacteria 1TQ1K@1239,3F3U4@33958,4HTTC@91061,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily LEHHPAIP_00265 349123.Lreu23DRAFT_3461 1e-66 259.2 Lactobacillaceae rbsD GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009056,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016052,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0016887,GO:0017111,GO:0019303,GO:0019321,GO:0019323,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0042802,GO:0043211,GO:0043492,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:1901575 5.4.99.62 ko:K06726 ko02010,map02010 R08247 RC02247 ko00000,ko00001,ko01000 iAF1260.b3748,iBWG_1329.BWG_3439,iECDH10B_1368.ECDH10B_3936,iECDH1ME8569_1439.ECDH1ME8569_3636,iECH74115_1262.ECH74115_5184,iECSP_1301.ECSP_4798,iECs_1301.ECs4690,iETEC_1333.ETEC_4039,iEcDH1_1363.EcDH1_4219,iJO1366.b3748,iJR904.b3748,iY75_1357.Y75_RS18330 Bacteria 1VA2V@1239,3F6GA@33958,4HIFW@91061,COG1869@1,COG1869@2 NA|NA|NA G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose LEHHPAIP_00266 557436.Lreu_0404 1.1e-164 585.9 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway LEHHPAIP_00267 557436.Lreu_0403 3e-167 594.3 Lactobacillaceae murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP3W@1239,3F40T@33958,4HAD8@91061,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation LEHHPAIP_00268 349123.Lreu23DRAFT_3458 3.9e-101 374.0 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1V57H@1239,3F42Z@33958,4HI1V@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III LEHHPAIP_00269 349123.Lreu23DRAFT_3457 2.2e-75 288.1 Lactobacillaceae ko:K09155 ko00000 Bacteria 1TRD5@1239,3F45M@33958,4HAAW@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain LEHHPAIP_00270 557436.Lreu_0400 4.4e-86 323.9 Lactobacillaceae Bacteria 1V22A@1239,3F7BU@33958,4ITA6@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain LEHHPAIP_00271 349123.Lreu23DRAFT_3455 2.2e-79 301.6 Lactobacillaceae ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 1V6CV@1239,3F3MR@33958,4HIIF@91061,COG0802@1,COG0802@2 NA|NA|NA O Hydrolase, P-loop family LEHHPAIP_00272 349123.Lreu23DRAFT_3454 1.1e-178 632.5 Lactobacillaceae pta 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iSB619.SA_RS03155 Bacteria 1TPQ0@1239,3F3MW@33958,4H9VH@91061,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase LEHHPAIP_00273 557436.Lreu_0397 1.8e-135 488.4 Lactobacillaceae ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSN@1239,3F3W0@33958,4HBTR@91061,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine LEHHPAIP_00274 557436.Lreu_0396 9.1e-104 382.9 Lactobacillaceae yxjI ko:K21429 ko00000,ko01002 Bacteria 1V8EY@1239,3F698@33958,4HMMS@91061,COG4894@1,COG4894@2 NA|NA|NA LEHHPAIP_00275 349123.Lreu23DRAFT_3451 1.4e-83 315.5 Lactobacillaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,3F65B@33958,4HGZX@91061,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA LEHHPAIP_00276 349123.Lreu23DRAFT_3450 0.0 1464.9 Lactobacillaceae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQ1G@1239,3F4EC@33958,4HBBH@91061,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs LEHHPAIP_00277 349123.Lreu23DRAFT_3449 3.2e-141 507.7 Lactobacillaceae est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 1TQ7X@1239,3F5XW@33958,4HBE6@91061,COG1647@1,COG1647@2 NA|NA|NA S Serine aminopeptidase, S33 LEHHPAIP_00278 557436.Lreu_0392 1.8e-34 151.4 Lactobacillaceae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEQR@1239,3F7IQ@33958,4HNKC@91061,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase LEHHPAIP_00279 557436.Lreu_0391 9e-292 1008.8 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F3MU@33958,4HD2H@91061,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P chloride LEHHPAIP_00280 349123.Lreu23DRAFT_3446 1.2e-244 852.0 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease LEHHPAIP_00281 349123.Lreu23DRAFT_3445 4.2e-250 870.2 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1TP2S@1239,3F3JP@33958,4HAKI@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis LEHHPAIP_00282 349123.Lreu23DRAFT_3444 4.5e-140 503.8 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) LEHHPAIP_00283 349123.Lreu23DRAFT_3443 1.2e-227 795.4 Lactobacillaceae pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS04145 Bacteria 1TP3H@1239,3F3SC@33958,4H9R3@91061,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family LEHHPAIP_00284 349123.Lreu23DRAFT_3442 1.1e-189 669.1 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F3JS@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family LEHHPAIP_00286 349123.Lreu23DRAFT_3439 2.1e-103 381.7 Lactobacillaceae clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQ91@1239,3F3M0@33958,4HA8J@91061,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins LEHHPAIP_00287 525309.HMPREF0494_0122 9.4e-17 94.0 Lactobacillaceae Bacteria 1U746@1239,29PW0@1,30AUA@2,3F8Y6@33958,4IGYS@91061 NA|NA|NA LEHHPAIP_00288 349123.Lreu23DRAFT_4800 5.1e-159 567.0 Lactobacillaceae Bacteria 1TP77@1239,3F3VP@33958,4HAZB@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_00289 557436.Lreu_1906 3.8e-85 320.9 Lactobacillaceae lacA Bacteria 1TSQQ@1239,3F73Z@33958,4HJJ7@91061,COG0110@1,COG0110@2 NA|NA|NA S transferase hexapeptide repeat LEHHPAIP_00290 525365.HMPREF0548_1226 3.1e-133 481.5 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TPW7@1239,3F5IC@33958,4HEFQ@91061,COG1073@1,COG1073@2 NA|NA|NA S Hydrolases of the alpha beta superfamily LEHHPAIP_00291 349123.Lreu23DRAFT_4797 2.6e-12 77.4 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase LEHHPAIP_00292 557436.Lreu_1905 1.7e-89 335.5 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase LEHHPAIP_00293 557436.Lreu_1904 1.7e-153 548.5 Lactobacillaceae tesE ko:K02509 ko00350,ko01120,map00350,map01120 R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 Bacteria 1TQVG@1239,3F515@33958,4HBMC@91061,COG3971@1,COG3971@2 NA|NA|NA Q hydratase LEHHPAIP_00294 557436.Lreu_1903 6.5e-176 623.2 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily LEHHPAIP_00295 557436.Lreu_1902 2.4e-228 797.7 Lactobacillaceae aadAT ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 R01939 RC00006 ko00000,ko00001,ko01000 Bacteria 1TPS5@1239,3F4AH@33958,4H9M3@91061,COG1167@1,COG1167@2 NA|NA|NA EK Aminotransferase, class I LEHHPAIP_00296 557436.Lreu_1901 2.3e-155 555.1 Lactobacillaceae ypuA Bacteria 1TR2I@1239,3FBNF@33958,4HBVZ@91061,COG4086@1,COG4086@2 NA|NA|NA S Protein of unknown function (DUF1002) LEHHPAIP_00297 557436.Lreu_1900 7.5e-183 646.4 Lactobacillaceae ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1TPP9@1239,3FCC6@33958,4HD98@91061,COG0252@1,COG0252@2 NA|NA|NA EJ L-asparaginase, type I LEHHPAIP_00298 557436.Lreu_1899 9.3e-145 519.6 Lactobacillaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UZXK@1239,3F41Q@33958,4HUWT@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_00299 557436.Lreu_1898 2.3e-159 568.2 Lactobacillaceae akr5f 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase LEHHPAIP_00300 575605.ACQN01000026_gene742 7.5e-99 367.1 Lactobacillaceae qorB 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1TT90@1239,3F4UU@33958,4HC1K@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family LEHHPAIP_00301 557436.Lreu_1894 4.2e-59 233.8 Lactobacillaceae yneR Bacteria 1U71X@1239,3F8VF@33958,4IGWD@91061,COG4841@1,COG4841@2 NA|NA|NA LEHHPAIP_00302 349123.Lreu23DRAFT_4788 7.2e-129 466.5 Lactobacillaceae yfeJ 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1V98D@1239,3FBR8@33958,4HK2D@91061,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase LEHHPAIP_00303 557436.Lreu_1891 1.6e-138 498.8 Lactobacillaceae Bacteria 1VM9X@1239,3F5AS@33958,4IF18@91061,COG2200@1,COG2200@2 NA|NA|NA T EAL domain LEHHPAIP_00304 557436.Lreu_1890 2.2e-246 857.8 Lactobacillaceae pgaC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0007155,GO:0008150,GO:0008194,GO:0008375,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0022610,GO:0031589,GO:0042710,GO:0043708,GO:0044464,GO:0044764,GO:0051704,GO:0071944,GO:0090605 ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 Bacteria 1TR2P@1239,3F3RY@33958,4HAQN@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase LEHHPAIP_00305 557436.Lreu_1889 3.7e-82 310.8 Lactobacillaceae Bacteria 1VG2N@1239,2E4JE@1,32ZEG@2,3F6QS@33958,4HPPN@91061 NA|NA|NA LEHHPAIP_00306 557436.Lreu_1888 5e-171 607.1 Lactobacillaceae 2.7.7.65 ko:K20955 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1V9Y7@1239,3FC2R@33958,4HQBN@91061,COG2199@1,COG3706@2 NA|NA|NA T GGDEF domain LEHHPAIP_00307 557436.Lreu_1887 2.2e-120 438.3 Bacilli yhjH GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006355,GO:0008081,GO:0008134,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0040012,GO:0040013,GO:0042578,GO:0043392,GO:0043433,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051090,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051252,GO:0051270,GO:0051271,GO:0060255,GO:0065007,GO:0065009,GO:0071111,GO:0080090,GO:1902021,GO:1902201,GO:1903506,GO:2000112,GO:2000145,GO:2000146,GO:2000677,GO:2000678,GO:2001141 3.1.4.52 ko:K21086 ko02026,map02026 ko00000,ko00001,ko01000 Bacteria 1W185@1239,4HYC2@91061,COG2200@1,COG2200@2 NA|NA|NA T Putative diguanylate phosphodiesterase LEHHPAIP_00308 349123.Lreu23DRAFT_4786 1e-256 892.1 Lactobacillaceae asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,3F4EK@33958,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase LEHHPAIP_00309 349123.Lreu23DRAFT_4785 4.9e-198 696.8 Lactobacillaceae asnA GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 R00483 RC00010 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299 Bacteria 1TP28@1239,3F40A@33958,4HAEC@91061,COG2502@1,COG2502@2 NA|NA|NA F aspartate--ammonia ligase LEHHPAIP_00310 557436.Lreu_1884 1e-17 95.1 Lactobacillaceae folT Bacteria 1V5I7@1239,3F5GB@33958,4HK9Q@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF transporter, substrate-specific component LEHHPAIP_00311 557436.Lreu_1884 6.1e-39 166.4 Lactobacillaceae folT Bacteria 1V5I7@1239,3F5GB@33958,4HK9Q@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF transporter, substrate-specific component LEHHPAIP_00312 575605.ACQN01000026_gene741 5.5e-48 197.2 Lactobacillaceae Bacteria 1V6FK@1239,3F73Q@33958,4HKZD@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_00313 349123.Lreu23DRAFT_4783 0.0 1667.9 Lactobacillaceae pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR43@1239,3F3UH@33958,4HA20@91061,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase LEHHPAIP_00314 557436.Lreu_1882 1.8e-84 318.5 Lactobacillaceae ylbE Bacteria 1V8TX@1239,3FB6T@33958,4HJBS@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD dependent epimerase dehydratase family protein LEHHPAIP_00315 349123.Lreu23DRAFT_4782 1.3e-12 77.8 Lactobacillaceae ylbE Bacteria 1V8TX@1239,3FB6T@33958,4HJBS@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD dependent epimerase dehydratase family protein LEHHPAIP_00316 349123.Lreu23DRAFT_4781 8.8e-256 889.0 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F3QA@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase LEHHPAIP_00317 349123.Lreu23DRAFT_4780 2.2e-210 738.0 Lactobacillaceae Bacteria 1TQHD@1239,3FB93@33958,4HBCZ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00318 349123.Lreu23DRAFT_4779 6.8e-232 809.7 Lactobacillaceae Bacteria 1U5A3@1239,29NNJ@1,309KH@2,3F5BX@33958,4IF1J@91061 NA|NA|NA LEHHPAIP_00319 557436.Lreu_1878 4e-83 313.9 Lactobacillaceae Bacteria 1V43K@1239,3F6PX@33958,4HH01@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family LEHHPAIP_00320 557436.Lreu_1877 4.1e-107 394.0 Lactobacillaceae XK27_02070 ko:K07078 ko00000 Bacteria 1V1CR@1239,3F576@33958,4HD6W@91061,COG3560@1,COG3560@2 NA|NA|NA S Nitroreductase family LEHHPAIP_00321 557436.Lreu_1876 1.8e-50 204.9 Lactobacillaceae hxlR Bacteria 1VA9M@1239,3F7S1@33958,4HH0A@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family LEHHPAIP_00322 557436.Lreu_1875 1.2e-120 439.1 Lactobacillaceae Bacteria 1UJSC@1239,3F4ZZ@33958,4HCVT@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family LEHHPAIP_00323 349123.Lreu23DRAFT_4774 1.6e-73 282.0 Bacilli elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 1VAJY@1239,4HIH7@91061,COG2153@1,COG2153@2 NA|NA|NA S Gnat family LEHHPAIP_00324 557436.Lreu_1873 5.7e-36 156.4 Lactobacillaceae Bacteria 1V64Y@1239,3F812@33958,4HNUM@91061,COG4892@1,COG4892@2 NA|NA|NA S Cytochrome B5 LEHHPAIP_00325 349123.Lreu23DRAFT_4770 1.3e-218 765.4 Lactobacillaceae yxjG_1 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent LEHHPAIP_00327 349123.Lreu23DRAFT_4768 2.8e-15 86.7 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1NJ@1239,3FCCR@33958,4HFWT@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid LEHHPAIP_00328 557436.Lreu_1867 8.6e-119 433.0 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1NJ@1239,3FCCR@33958,4HFWT@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid LEHHPAIP_00329 557436.Lreu_1866 1.5e-237 828.6 Lactobacillaceae ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3K6@33958,4HCZ0@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00330 349123.Lreu23DRAFT_4766 2.8e-31 141.0 Lactobacillaceae npp Bacteria 1TRZ7@1239,3F4V5@33958,4HAY5@91061,COG1524@1,COG1524@2 NA|NA|NA S type I phosphodiesterase nucleotide pyrophosphatase LEHHPAIP_00331 557436.Lreu_1865 1.7e-47 194.9 Lactobacillaceae npp Bacteria 1TRZ7@1239,3F4V5@33958,4HAY5@91061,COG1524@1,COG1524@2 NA|NA|NA S type I phosphodiesterase nucleotide pyrophosphatase LEHHPAIP_00332 349123.Lreu23DRAFT_4766 1.1e-101 375.9 Lactobacillaceae npp Bacteria 1TRZ7@1239,3F4V5@33958,4HAY5@91061,COG1524@1,COG1524@2 NA|NA|NA S type I phosphodiesterase nucleotide pyrophosphatase LEHHPAIP_00333 349123.Lreu23DRAFT_4765 4.2e-84 317.4 Lactobacillaceae yxiO ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 1TRTH@1239,3F5D5@33958,4H9VB@91061,COG2270@1,COG2270@2 NA|NA|NA S Vacuole effluxer Atg22 like LEHHPAIP_00334 349123.Lreu23DRAFT_4765 1.2e-74 285.8 Lactobacillaceae yxiO ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 1TRTH@1239,3F5D5@33958,4H9VB@91061,COG2270@1,COG2270@2 NA|NA|NA S Vacuole effluxer Atg22 like LEHHPAIP_00337 349123.Lreu23DRAFT_4761 0.0 1201.8 Lactobacillaceae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP78@1239,3F3TC@33958,4HABZ@91061,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) LEHHPAIP_00338 557436.Lreu_1862 1.5e-28 133.3 Lactobacillaceae Bacteria 1U6N1@1239,29PIM@1,30AGS@2,3F86A@33958,4IGEW@91061 NA|NA|NA LEHHPAIP_00339 349123.Lreu23DRAFT_4421 1.5e-147 528.9 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TPW7@1239,3F5IC@33958,4HEFQ@91061,COG1073@1,COG1073@2 NA|NA|NA S Hydrolases of the alpha beta superfamily LEHHPAIP_00340 349123.Lreu23DRAFT_4420 8e-196 689.5 Lactobacillaceae adhP GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0006081,GO:0006117,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0045471,GO:0046185,GO:0046187,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0097305,GO:1901575,GO:1901700 1.1.1.1 ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 iECP_1309.ECP_1480 Bacteria 1TP5B@1239,3F4PR@33958,4HA9Z@91061,COG1064@1,COG1064@2 NA|NA|NA C alcohol dehydrogenase LEHHPAIP_00341 349123.Lreu23DRAFT_4419 4.4e-77 293.9 Lactobacillaceae ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03708 ko00000,ko03000 Bacteria 1VAXT@1239,3F53E@33958,4HIFT@91061,COG4463@1,COG4463@2 NA|NA|NA K Belongs to the CtsR family LEHHPAIP_00342 557436.Lreu_1494 0.0 1588.9 Lactobacillaceae clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE LEHHPAIP_00343 349123.Lreu23DRAFT_4415 3e-110 404.4 Lactobacillaceae ko:K09017 ko00000,ko03000 Bacteria 1UYPI@1239,3FBFF@33958,4IQ2E@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family LEHHPAIP_00344 349123.Lreu23DRAFT_4414 0.0 2356.6 Lactobacillaceae rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TP96@1239,3F4ET@33958,4H9PK@91061,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates LEHHPAIP_00345 349123.Lreu23DRAFT_4413 0.0 2385.1 Lactobacillaceae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TNYT@1239,3F3KF@33958,4HA24@91061,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates LEHHPAIP_00346 557436.Lreu_1490 2.3e-199 701.4 Lactobacillaceae ykiI Bacteria 1VRBZ@1239,2DSXT@1,32UTZ@2,3F4NM@33958,4HT22@91061 NA|NA|NA LEHHPAIP_00347 349123.Lreu23DRAFT_4411 1.7e-106 392.1 Bacilli pilD 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 1TQY4@1239,4HCC3@91061,COG1989@1,COG1989@2 NA|NA|NA NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases LEHHPAIP_00348 349123.Lreu23DRAFT_4410 3.9e-72 277.3 Lactobacillaceae rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FJ@1239,3F64B@33958,4HFMZ@91061,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit LEHHPAIP_00349 557436.Lreu_1487 2.4e-83 314.7 Lactobacillaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1GG@1239,3F3RX@33958,4H9PA@91061,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA LEHHPAIP_00350 349123.Lreu23DRAFT_4408 0.0 1373.6 Lactobacillaceae fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPF9@1239,3F3JR@33958,4HAB8@91061,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome LEHHPAIP_00351 349123.Lreu23DRAFT_4406 3.4e-49 200.7 Lactobacillaceae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6C9@1239,3F6KC@33958,4HIKH@91061,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes LEHHPAIP_00352 349123.Lreu23DRAFT_4405 1.5e-118 432.2 Lactobacillaceae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPFT@1239,3F45I@33958,4HAEN@91061,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit LEHHPAIP_00353 349123.Lreu23DRAFT_4404 5.5e-107 393.7 Lactobacillaceae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPGW@1239,3F3QD@33958,4HB01@91061,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel LEHHPAIP_00354 349123.Lreu23DRAFT_4403 5.7e-46 189.9 Lactobacillaceae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA4W@1239,3F6Z2@33958,4HKCV@91061,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome LEHHPAIP_00355 349123.Lreu23DRAFT_4402 4.2e-150 537.3 Lactobacillaceae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TP9X@1239,3F3XI@33958,4HAE8@91061,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity LEHHPAIP_00356 349123.Lreu23DRAFT_4401 1.4e-46 191.8 Lactobacillaceae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6CX@1239,3F6XP@33958,4HIG0@91061,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA LEHHPAIP_00357 349123.Lreu23DRAFT_4400 2.8e-52 211.1 Lactobacillaceae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6PU@1239,3F6K6@33958,4HIK2@91061,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome LEHHPAIP_00358 349123.Lreu23DRAFT_4399 6.1e-112 410.2 Lactobacillaceae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPCP@1239,3F3Q8@33958,4HAUR@91061,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation LEHHPAIP_00359 349123.Lreu23DRAFT_4398 3.5e-76 290.8 Lactobacillaceae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1AY@1239,3F653@33958,4HFPN@91061,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs LEHHPAIP_00360 349123.Lreu23DRAFT_4397 8.4e-28 129.0 Lactobacillaceae rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEME@1239,3F82Z@33958,4HNUP@91061,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family LEHHPAIP_00361 349123.Lreu23DRAFT_4396 5e-41 173.3 Lactobacillaceae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YC@1239,3F7FX@33958,4HKDN@91061,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA LEHHPAIP_00362 349123.Lreu23DRAFT_4395 1.1e-59 235.7 Lactobacillaceae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3N0@1239,3F6GT@33958,4HGYR@91061,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome LEHHPAIP_00363 349123.Lreu23DRAFT_4394 2.6e-49 201.1 Lactobacillaceae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,3F6X5@33958,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit LEHHPAIP_00364 557436.Lreu_1471 1.4e-95 355.5 Lactobacillaceae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPE0@1239,3F3Q7@33958,4HBAX@91061,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits LEHHPAIP_00365 349123.Lreu23DRAFT_4391 1.3e-66 258.8 Lactobacillaceae rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,3F64E@33958,4HH32@91061,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit LEHHPAIP_00366 349123.Lreu23DRAFT_4390 2.1e-94 351.7 Lactobacillaceae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FC@1239,3F4G5@33958,4HFQD@91061,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center LEHHPAIP_00367 349123.Lreu23DRAFT_4389 6.6e-57 226.5 Lactobacillaceae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DM@1239,3F6KN@33958,4HIGF@91061,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance LEHHPAIP_00368 349123.Lreu23DRAFT_4388 6.3e-85 320.1 Lactobacillaceae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1B1@1239,3F3VY@33958,4HFN4@91061,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body LEHHPAIP_00369 349123.Lreu23DRAFT_4387 2.9e-24 117.1 Lactobacillaceae rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEG4@1239,3F7ZU@33958,4HNHF@91061,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 LEHHPAIP_00370 349123.Lreu23DRAFT_4386 1.5e-63 248.8 Lactobacillaceae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KE@1239,3F675@33958,4HFPW@91061,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA LEHHPAIP_00371 349123.Lreu23DRAFT_4385 1.7e-238 831.6 Lactobacillaceae secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1TPHB@1239,3F4FV@33958,4HAWH@91061,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently LEHHPAIP_00372 349123.Lreu23DRAFT_4384 4.4e-123 447.2 Lactobacillaceae adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,3F3KB@33958,4HA89@91061,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism LEHHPAIP_00373 1423814.HMPREF0549_1406 1.2e-32 145.2 Lactobacillaceae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1V9ZK@1239,3F7CW@33958,4HKF4@91061,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex LEHHPAIP_00374 349123.Lreu23DRAFT_4382 1.4e-14 84.3 Lactobacillaceae rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK4F@1239,3F8TC@33958,4HR2X@91061,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family LEHHPAIP_00375 557436.Lreu_1459 6.2e-58 229.9 Lactobacillaceae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JH@1239,3F6GN@33958,4HGX6@91061,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits LEHHPAIP_00376 349123.Lreu23DRAFT_4380 2.3e-63 248.1 Lactobacillaceae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3IK@1239,3F67D@33958,4HH2T@91061,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome LEHHPAIP_00377 349123.Lreu23DRAFT_4379 2.8e-171 607.8 Lactobacillaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,3F3W6@33958,4H9R1@91061,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates LEHHPAIP_00378 349123.Lreu23DRAFT_4378 1.1e-62 245.7 Lactobacillaceae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6JQ@1239,3F6GJ@33958,4HGX2@91061,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 LEHHPAIP_00379 557436.Lreu_1455 4.2e-139 500.7 Lactobacillaceae ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F3VD@33958,4H9R8@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates LEHHPAIP_00380 557436.Lreu_1454 3.3e-150 537.7 Lactobacillaceae ecfA2 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363 3.6.3.55 ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00186,M00211,M00581,M00582 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4 Bacteria 1TPH8@1239,3F48E@33958,4HA7T@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates LEHHPAIP_00381 557436.Lreu_1453 1.7e-140 505.4 Lactobacillaceae ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQ0E@1239,3F3UW@33958,4H9VT@91061,COG0619@1,COG0619@2 NA|NA|NA U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates LEHHPAIP_00382 349123.Lreu23DRAFT_4374 4.2e-141 507.3 Lactobacillaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,3F4KC@33958,4HCFI@91061,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs LEHHPAIP_00383 349123.Lreu23DRAFT_4373 4.5e-79 300.4 Lactobacillaceae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3HX@1239,3F696@33958,4HG0I@91061,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly LEHHPAIP_00384 349123.Lreu23DRAFT_4372 1.6e-64 251.9 Lactobacillaceae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3MQ@1239,3F656@33958,4HH3B@91061,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family LEHHPAIP_00385 349123.Lreu23DRAFT_4371 8e-140 503.1 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase LEHHPAIP_00386 557436.Lreu_1448 1.5e-112 412.1 Lactobacillaceae acmC 3.2.1.96 ko:K01227,ko:K02395 ko00511,map00511 ko00000,ko00001,ko01000,ko02035 Bacteria 1V7JY@1239,3F584@33958,4HIY4@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein LEHHPAIP_00387 349123.Lreu23DRAFT_4369 2.3e-99 368.2 Lactobacillaceae xpt GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko04147 iYO844.BSU22070 Bacteria 1V1DU@1239,3F49S@33958,4HFNW@91061,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis LEHHPAIP_00388 349123.Lreu23DRAFT_4368 2.1e-210 738.0 Lactobacillaceae purK2 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3FC8U@33958,4HJI4@91061,COG0026@1,COG0026@2 NA|NA|NA F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate LEHHPAIP_00389 349123.Lreu23DRAFT_4365 0.0 1479.9 Lactobacillaceae pcrA 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,3F400@33958,4HB12@91061,COG0210@1,COG0210@2 NA|NA|NA L ATP-dependent DNA helicase LEHHPAIP_00390 557436.Lreu_1444 0.0 1325.1 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,3F43C@33958,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA LEHHPAIP_00391 349123.Lreu23DRAFT_4363 1.2e-202 712.2 Lactobacillaceae camS Bacteria 1TSYE@1239,3F3KI@33958,4HBI8@91061,COG4851@1,COG4851@2 NA|NA|NA S sex pheromone LEHHPAIP_00392 349123.Lreu23DRAFT_4362 7e-50 203.0 Lactobacillaceae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,3F7XB@33958,4HNNA@91061,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) LEHHPAIP_00393 557436.Lreu_1441 9.1e-278 962.2 Lactobacillaceae gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1TP0C@1239,3F4BK@33958,4HBAZ@91061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) LEHHPAIP_00394 349123.Lreu23DRAFT_4360 9.1e-275 952.2 Lactobacillaceae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPG3@1239,3F44H@33958,4HAFB@91061,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) LEHHPAIP_00395 557436.Lreu_1439 9.6e-186 656.0 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQAU@1239,3F447@33958,4H9WD@91061,COG1597@1,COG1597@2 NA|NA|NA G Lipid kinase LEHHPAIP_00396 557436.Lreu_1438 9.8e-258 895.6 Lactobacillaceae rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,3F41R@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family LEHHPAIP_00397 334390.LAF_1567 7.9e-14 82.4 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region LEHHPAIP_00398 944562.HMPREF9102_0723 3.7e-56 224.6 Lactobacillaceae ltrA Bacteria 1VAA8@1239,3FB87@33958,4HMPC@91061,COG4292@1,COG4292@2 NA|NA|NA S Bacterial low temperature requirement A protein (LtrA) LEHHPAIP_00399 908339.HMPREF9265_0607 2.6e-43 181.4 Lactobacillaceae ltrA Bacteria 1TR19@1239,3FB88@33958,4HCYV@91061,COG4292@1,COG4292@2 NA|NA|NA S Bacterial low temperature requirement A protein (LtrA) LEHHPAIP_00400 349123.Lreu23DRAFT_4664 1.6e-79 302.0 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein LEHHPAIP_00401 349123.Lreu23DRAFT_4665 4e-78 297.4 Lactobacillaceae ko:K03719 ko00000,ko03000,ko03036 Bacteria 1V3MI@1239,3F6FN@33958,4HJUY@91061,COG1522@1,COG1522@2 NA|NA|NA K AsnC family LEHHPAIP_00402 349123.Lreu23DRAFT_4667 4.5e-228 797.0 Lactobacillaceae gltP GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015849,GO:0016020,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702,GO:0071944 ko:K03309,ko:K11102 ko00000,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2 iPC815.YPO0254,iYO844.BSU10220 Bacteria 1TPME@1239,3F4Q2@33958,4H9T7@91061,COG1301@1,COG1301@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family LEHHPAIP_00403 557436.Lreu_1772 9.2e-99 366.3 Lactobacillaceae dedA 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1TS2R@1239,3F5F9@33958,4HA51@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein LEHHPAIP_00404 908339.HMPREF9265_1673 6.2e-10 69.3 Lactobacillaceae Bacteria 1V05W@1239,3F4R7@33958,4HSX6@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance LEHHPAIP_00405 349123.Lreu23DRAFT_4688 1.1e-167 595.9 Lactobacillaceae cysK GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family LEHHPAIP_00406 349123.Lreu23DRAFT_4687 3.8e-156 557.4 Lactobacillaceae metAA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11970 Bacteria 1TQVR@1239,3F5CA@33958,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to LEHHPAIP_00407 349123.Lreu23DRAFT_4686 0.0 1163.7 Lactobacillaceae ysaB ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 Bacteria 1TR2D@1239,3F45H@33958,4HAZG@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family LEHHPAIP_00408 557436.Lreu_1789 2.9e-134 484.6 Lactobacillaceae macB2 ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 Bacteria 1TNZG@1239,3F3MG@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein LEHHPAIP_00409 349123.Lreu23DRAFT_4684 5.3e-181 640.2 Lactobacillaceae Bacteria 1TSIC@1239,3F5QR@33958,4HFQK@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor LEHHPAIP_00410 349123.Lreu23DRAFT_4683 5.4e-124 450.3 Lactobacillaceae Bacteria 1TR32@1239,3F5NZ@33958,4HAUJ@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator LEHHPAIP_00411 349123.Lreu23DRAFT_4682 3.9e-156 557.4 Lactobacillaceae ytbE 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4T@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo keto reductase LEHHPAIP_00412 557436.Lreu_1785 2.4e-133 481.5 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1VE5T@1239,3F3MB@33958,4HMNW@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter LEHHPAIP_00413 349123.Lreu23DRAFT_4678 1.1e-81 309.3 Lactobacillaceae greA ko:K03624,ko:K04760 ko00000,ko03021 Bacteria 1V1G3@1239,3F6ZK@33958,4HW8H@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides LEHHPAIP_00414 557436.Lreu_1783 6.2e-202 709.9 Lactobacillaceae Bacteria 1UFYX@1239,29V2W@1,30GG3@2,3F5AU@33958,4IF19@91061 NA|NA|NA LEHHPAIP_00415 557436.Lreu_1782 3.5e-52 210.7 Lactobacillaceae Bacteria 1W304@1239,2905K@1,2ZMVG@2,3F7TH@33958,4I0TS@91061 NA|NA|NA LEHHPAIP_00416 349123.Lreu23DRAFT_4675 9.1e-36 155.6 Lactobacillaceae Bacteria 1W6D0@1239,2930D@1,2ZQHQ@2,3F7KZ@33958,4HZS5@91061 NA|NA|NA LEHHPAIP_00417 349123.Lreu23DRAFT_4674 3.1e-92 344.4 Lactobacillaceae yxkA ko:K06910 ko00000 Bacteria 1VJEE@1239,3FBPI@33958,4IRQB@91061,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein LEHHPAIP_00418 557436.Lreu_1779 1.2e-143 515.8 Lactobacillaceae ptp3 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V851@1239,3F55V@33958,4HJB2@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family LEHHPAIP_00419 349123.Lreu23DRAFT_4672 2.5e-175 621.3 Lactobacillaceae celE GO:0000272,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005975,GO:0005976,GO:0006073,GO:0006080,GO:0008150,GO:0008152,GO:0008810,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010391,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0016798,GO:0017144,GO:0030243,GO:0030245,GO:0030246,GO:0030247,GO:0030248,GO:0042737,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0045491,GO:0045493,GO:0046555,GO:0051273,GO:0051275,GO:0052689,GO:0071554,GO:0071704,GO:1901575,GO:2000884 3.2.1.4 ko:K01179,ko:K20276 ko00500,ko01100,ko02024,map00500,map01100,map02024 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1U9HW@1239,3F4VR@33958,4HQ3R@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family LEHHPAIP_00420 557436.Lreu_1777 1.6e-224 785.0 Lactobacillaceae galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPD0@1239,3F3Q9@33958,4HARP@91061,COG0153@1,COG0153@2 NA|NA|NA F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) LEHHPAIP_00421 349123.Lreu23DRAFT_4670 1.1e-278 965.3 Lactobacillaceae galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPBN@1239,3F4D8@33958,4HAYJ@91061,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase LEHHPAIP_00422 349123.Lreu23DRAFT_4669 5.4e-181 640.2 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_00424 349123.Lreu23DRAFT_3543 3.7e-82 310.8 Lactobacillaceae usp6 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1V3NY@1239,3F68T@33958,4HIP3@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein LEHHPAIP_00425 349123.Lreu23DRAFT_3544 4.4e-46 190.3 Lactobacillaceae Bacteria 1U6AT@1239,29P9H@1,30A7M@2,3F7GV@33958,4IG27@91061 NA|NA|NA LEHHPAIP_00426 557436.Lreu_0488 1.8e-240 838.2 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3WF@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA LEHHPAIP_00427 557436.Lreu_0489 1.8e-84 318.5 Lactobacillaceae yueI Bacteria 1VFCV@1239,3F64D@33958,4HNNE@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) LEHHPAIP_00428 349123.Lreu23DRAFT_4704 4.7e-21 107.1 Lactobacillaceae Bacteria 1U6JA@1239,29PGB@1,30AEG@2,3F80W@33958,4IGBU@91061 NA|NA|NA LEHHPAIP_00429 1280676.AUJO01000013_gene3503 4.3e-08 63.9 Butyrivibrio Bacteria 1VDA9@1239,24F9E@186801,4BXFZ@830,COG3274@1,COG3274@2 NA|NA|NA S Acyltransferase family LEHHPAIP_00430 557436.Lreu_0576 2.5e-64 251.1 Lactobacillaceae XK27_01125 ko:K07484 ko00000 Bacteria 1VAJD@1239,3F7E1@33958,4HKCG@91061,COG3436@1,COG3436@2 NA|NA|NA L PFAM IS66 Orf2 family protein LEHHPAIP_00432 349123.Lreu23DRAFT_4183 1e-68 266.2 Lactobacillaceae moaC GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 1V3J4@1239,3F65H@33958,4HH39@91061,COG0315@1,COG0315@2 NA|NA|NA H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) LEHHPAIP_00433 525309.HMPREF0494_1522 5.5e-45 186.8 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1VCAX@1239,3F9SC@33958,4HNBK@91061,COG2151@1,COG2151@2 NA|NA|NA S Pfam:DUF59 LEHHPAIP_00434 349123.Lreu23DRAFT_4185 1.6e-169 602.1 Lactobacillaceae moaA 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394 RC03420 ko00000,ko00001,ko01000 Bacteria 1TP89@1239,3F5T2@33958,4HAKQ@91061,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate LEHHPAIP_00438 349123.Lreu23DRAFT_3073 3.5e-97 360.9 Lactobacillaceae ltrA_1 Bacteria 1TP9A@1239,3F4TJ@33958,4H9NW@91061,COG3344@1,COG3344@2 NA|NA|NA L PFAM RNA-directed DNA polymerase (Reverse transcriptase) LEHHPAIP_00439 1296415.JACC01000099_gene1790 8.6e-47 192.6 Aquimarina ltrA_1 Bacteria 1HX5X@117743,2YJW3@290174,4NGGU@976,COG3344@1,COG3344@2 NA|NA|NA L Reverse transcriptase (RNA-dependent DNA polymerase) LEHHPAIP_00440 557436.Lreu_0576 5.6e-48 196.4 Lactobacillaceae XK27_01125 ko:K07484 ko00000 Bacteria 1VAJD@1239,3F7E1@33958,4HKCG@91061,COG3436@1,COG3436@2 NA|NA|NA L PFAM IS66 Orf2 family protein LEHHPAIP_00441 349123.Lreu23DRAFT_4094 3.3e-56 224.2 Lactobacillaceae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DB@1239,3F6HZ@33958,4HH2W@91061,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit LEHHPAIP_00442 349123.Lreu23DRAFT_4095 2.3e-27 127.5 Lactobacillaceae rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VF5W@1239,3F7CQ@33958,4HNIQ@91061,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family LEHHPAIP_00443 349123.Lreu23DRAFT_4096 3.7e-85 320.9 Lactobacillaceae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1V1RC@1239,3F4MS@33958,4HFUS@91061,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins LEHHPAIP_00444 557436.Lreu_1242 1.9e-172 611.7 Lactobacillaceae dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K11144 ko00000,ko03032 Bacteria 1TPZX@1239,3F4JK@33958,4HABS@91061,COG1484@1,COG1484@2 NA|NA|NA L Primosomal protein DnaI LEHHPAIP_00445 349123.Lreu23DRAFT_4098 1.9e-221 775.0 Lactobacillaceae dnaB ko:K03346 ko00000,ko03032 Bacteria 1TSBB@1239,3F5D7@33958,4H9RI@91061,COG3611@1,COG3611@2 NA|NA|NA L replication initiation and membrane attachment LEHHPAIP_00446 557436.Lreu_1244 1.1e-80 305.8 Lactobacillaceae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,3F65S@33958,4HGXA@91061,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes LEHHPAIP_00447 557436.Lreu_1245 5e-97 360.5 Lactobacillaceae coaE 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6FS@1239,3F6WF@33958,4HII3@91061,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A LEHHPAIP_00448 557436.Lreu_1246 4.1e-158 563.9 Lactobacillaceae fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPM9@1239,3F43E@33958,4H9Q7@91061,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates LEHHPAIP_00449 557436.Lreu_1247 0.0 1742.6 Lactobacillaceae polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPKJ@1239,3F3ZA@33958,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity LEHHPAIP_00450 349123.Lreu23DRAFT_4103 1e-15 88.2 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) LEHHPAIP_00451 557436.Lreu_1248 2.4e-72 278.1 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) LEHHPAIP_00452 557436.Lreu_1249 1.4e-119 435.6 Lactobacillaceae ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V66F@1239,3FBMP@33958,4IR6X@91061,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family LEHHPAIP_00453 557436.Lreu_1250 1.1e-250 872.1 Lactobacillaceae mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 1TQ5H@1239,3F49J@33958,4HAR4@91061,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family LEHHPAIP_00454 557436.Lreu_1251 9.4e-118 429.5 Lactobacillaceae pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V3R1@1239,3F58U@33958,4HHBI@91061,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily LEHHPAIP_00455 349123.Lreu23DRAFT_4110 1.8e-53 214.9 Lactobacillaceae ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1VAS6@1239,3F72K@33958,4HKGM@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin LEHHPAIP_00456 349123.Lreu23DRAFT_4111 1.1e-56 225.7 Lactobacillaceae ytzB Bacteria 1VMU8@1239,3F73X@33958,4HREZ@91061,COG5584@1,COG5584@2 NA|NA|NA S Small secreted protein LEHHPAIP_00457 349123.Lreu23DRAFT_4112 2.6e-11 73.2 Lactobacillaceae glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0040008,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045926,GO:0046394,GO:0046395,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 iB21_1397.B21_01492,iECBD_1354.ECBD_2118,iECB_1328.ECB_01481,iECD_1391.ECD_01481,iYL1228.KPN_01636,iYO844.BSU02430 Bacteria 1TP64@1239,3F4NW@33958,4H9XA@91061,COG2066@1,COG2066@2 NA|NA|NA E Belongs to the glutaminase family LEHHPAIP_00458 349123.Lreu23DRAFT_4115 1.3e-64 252.3 Bacteria 2.1.1.72,3.1.21.3 ko:K01154,ko:K02014,ko:K03933,ko:K07316 ko00000,ko01000,ko02000,ko02048 1.B.14 AA10,CBM73 Bacteria COG1629@1,COG1629@2,COG2189@1,COG2189@2,COG4932@1,COG4932@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family LEHHPAIP_00459 349123.Lreu23DRAFT_4115 1.3e-12 78.6 Bacteria 2.1.1.72,3.1.21.3 ko:K01154,ko:K02014,ko:K03933,ko:K07316 ko00000,ko01000,ko02000,ko02048 1.B.14 AA10,CBM73 Bacteria COG1629@1,COG1629@2,COG2189@1,COG2189@2,COG4932@1,COG4932@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family LEHHPAIP_00460 349123.Lreu23DRAFT_4115 9.5e-16 90.1 Bacteria 2.1.1.72,3.1.21.3 ko:K01154,ko:K02014,ko:K03933,ko:K07316 ko00000,ko01000,ko02000,ko02048 1.B.14 AA10,CBM73 Bacteria COG1629@1,COG1629@2,COG2189@1,COG2189@2,COG4932@1,COG4932@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family LEHHPAIP_00461 349123.Lreu23DRAFT_4117 2.5e-16 90.5 Lactobacillaceae Bacteria 1UHXX@1239,29W6X@1,30HS4@2,3F8TA@33958,4ISAB@91061 NA|NA|NA S YSIRK type signal peptide LEHHPAIP_00462 349123.Lreu23DRAFT_4118 3.1e-121 441.0 Lactobacillaceae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1TQCA@1239,3F3QM@33958,4HC08@91061,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA LEHHPAIP_00463 557436.Lreu_1261 3.9e-218 763.8 Lactobacillaceae ecsB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1VG@1239,3F4HH@33958,4HG1K@91061,COG4473@1,COG4473@2 NA|NA|NA U ABC transporter LEHHPAIP_00464 349123.Lreu23DRAFT_4120 6.7e-136 490.0 Lactobacillaceae ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3F444@33958,4HA2B@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein LEHHPAIP_00465 557436.Lreu_1263 1.2e-76 292.4 Lactobacillaceae hit ko:K02503 ko00000,ko04147 Bacteria 1V9ZJ@1239,3F6K5@33958,4HIG2@91061,COG0537@1,COG0537@2 NA|NA|NA FG histidine triad LEHHPAIP_00467 349123.Lreu23DRAFT_4123 8.5e-128 463.4 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1V5RY@1239,3FBHM@33958,4HH41@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins LEHHPAIP_00468 349123.Lreu23DRAFT_4124 0.0 1469.1 Lactobacillaceae Bacteria 1TQP3@1239,3F3PF@33958,4HBCA@91061,COG4717@1,COG4717@2 NA|NA|NA L AAA domain LEHHPAIP_00469 557436.Lreu_1267 2.8e-221 774.2 Lactobacillaceae yhaO ko:K03547 ko00000,ko03400 Bacteria 1TWMI@1239,3F3PX@33958,4HCA0@91061,COG0420@1,COG0420@2 NA|NA|NA L Ser Thr phosphatase family protein LEHHPAIP_00470 557436.Lreu_1268 9.4e-38 162.9 Lactobacillaceae yheA Bacteria 1VASS@1239,3F822@33958,4HKKC@91061,COG3679@1,COG3679@2 NA|NA|NA S Belongs to the UPF0342 family LEHHPAIP_00471 349123.Lreu23DRAFT_4127 0.0 1346.6 Lactobacillaceae pbp2A 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F49Q@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein LEHHPAIP_00472 557436.Lreu_1270 0.0 1112.1 Lactobacillaceae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPEZ@1239,3F4DE@33958,4HAR3@91061,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase LEHHPAIP_00473 349123.Lreu23DRAFT_4130 2.1e-151 541.6 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase LEHHPAIP_00474 349123.Lreu23DRAFT_4131 3.5e-166 590.9 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family LEHHPAIP_00476 349123.Lreu23DRAFT_4132 1.3e-36 158.7 Lactobacillaceae Bacteria 1U6CF@1239,2DKPT@1,30A91@2,3F7KP@33958,4IG44@91061 NA|NA|NA LEHHPAIP_00477 349123.Lreu23DRAFT_4133 5.1e-43 180.3 Lactobacillaceae Bacteria 1U6NG@1239,29PIY@1,30AH3@2,3F870@33958,4IGFF@91061 NA|NA|NA LEHHPAIP_00478 557436.Lreu_1275 2.1e-208 731.5 Lactobacillaceae folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796,ko:K18824,ko:K18974 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPKT@1239,3F4SS@33958,4H9SY@91061,COG0294@1,COG0294@2 NA|NA|NA H dihydropteroate synthase LEHHPAIP_00479 349123.Lreu23DRAFT_4135 1.3e-102 379.0 Lactobacillaceae xtp 2.5.1.15,3.6.1.66 ko:K00796,ko:K02428 ko00230,ko00790,ko01100,map00230,map00790,map01100 M00126,M00841 R00426,R00720,R01855,R02100,R02720,R03066,R03067,R03531 RC00002,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 1VWAB@1239,3F4R5@33958,4HWPY@91061,COG0127@1,COG0127@2 NA|NA|NA F Ham1 family LEHHPAIP_00480 557436.Lreu_1277 4.7e-222 776.9 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPX5@1239,3F3ZR@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family LEHHPAIP_00481 349123.Lreu23DRAFT_4137 6.9e-104 383.3 Lactobacillaceae folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3609c Bacteria 1TRNM@1239,3F4A0@33958,4HAXS@91061,COG0302@1,COG0302@2 NA|NA|NA F GTP cyclohydrolase 1 LEHHPAIP_00482 557436.Lreu_1279 2.9e-90 337.8 Lactobacillaceae folK 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6PR@1239,3F6SY@33958,4HIMG@91061,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) LEHHPAIP_00483 557436.Lreu_1280 2.6e-55 221.1 Lactobacillaceae folB 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA0I@1239,3F7N6@33958,4HKKK@91061,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin LEHHPAIP_00484 557436.Lreu_1281 8.4e-69 266.2 Lactobacillaceae Bacteria 1VMB8@1239,2EG6W@1,339YS@2,3F80J@33958,4HRH5@91061 NA|NA|NA LEHHPAIP_00486 349123.Lreu23DRAFT_4143 2.5e-43 181.0 Lactobacillaceae Bacteria 1W0FC@1239,2FCT0@1,344W0@2,3F7QR@33958,4HXX0@91061 NA|NA|NA LEHHPAIP_00487 349123.Lreu23DRAFT_4144 2.7e-109 401.4 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VFRX@1239,3F4Q0@33958,4HRQQ@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity LEHHPAIP_00488 557436.Lreu_1284 3.1e-31 140.6 Lactobacillaceae Bacteria 1U6ME@1239,2AI9B@1,318PY@2,3F85B@33958,4IGE9@91061 NA|NA|NA LEHHPAIP_00489 557436.Lreu_1285 6.8e-162 576.6 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3FB6B@33958,4HE6Z@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway LEHHPAIP_00490 557436.Lreu_1286 7.4e-186 656.4 Lactobacillaceae rbsR ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F44Q@33958,4HE07@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding proteins and sugar binding domain of LacI family LEHHPAIP_00491 557436.Lreu_1287 2.2e-113 414.8 Lactobacillaceae Bacteria 1U5EA@1239,29NQX@1,309NV@2,3F5Q3@33958,4IF5Q@91061 NA|NA|NA LEHHPAIP_00492 349123.Lreu23DRAFT_4149 5e-116 423.7 Lactobacillaceae dck 2.7.1.74 ko:K00893 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F4MY@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase LEHHPAIP_00493 557436.Lreu_1289 1.4e-176 625.5 Lactobacillaceae ko:K02395 ko00000,ko02035 Bacteria 1UYRM@1239,3FC1U@33958,4HVMB@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase LEHHPAIP_00494 557436.Lreu_1290 7.3e-86 323.2 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VMC9@1239,3F6UZ@33958,4HYXY@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family LEHHPAIP_00495 349123.Lreu23DRAFT_4152 8.1e-276 955.7 Lactobacillaceae pepV 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPEG@1239,3F3UV@33958,4HC14@91061,COG0624@1,COG0624@2 NA|NA|NA E dipeptidase PepV LEHHPAIP_00496 349123.Lreu23DRAFT_4153 5.4e-153 547.0 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1TNZE@1239,3F480@33958,4HBZC@91061,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration LEHHPAIP_00497 557436.Lreu_1293 1.1e-300 1038.5 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein LEHHPAIP_00498 349123.Lreu23DRAFT_4155 7.6e-42 176.0 Lactobacillaceae Bacteria 1W40S@1239,28VX1@1,2ZHYD@2,3F7NY@33958,4I25G@91061 NA|NA|NA LEHHPAIP_00499 349123.Lreu23DRAFT_4156 0.0 1681.0 Lactobacillaceae leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TP0Y@1239,3F46M@33958,4HAG1@91061,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family LEHHPAIP_00500 349123.Lreu23DRAFT_4157 5.6e-217 760.0 Lactobacillaceae metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCV@1239,3F3T0@33958,4HB33@91061,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme LEHHPAIP_00501 557436.Lreu_1297 5.1e-93 347.1 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UYWG@1239,3F5KA@33958,4HGWW@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase LEHHPAIP_00502 349123.Lreu23DRAFT_4160 4.6e-258 896.7 Lactobacillaceae Bacteria 1TS0Y@1239,3F4GE@33958,4HEMR@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00503 349123.Lreu23DRAFT_4161 2.8e-84 317.8 Lactobacillaceae perR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K03711,ko:K09825 ko00000,ko03000 Bacteria 1V400@1239,3F67J@33958,4HHF8@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family LEHHPAIP_00504 349123.Lreu23DRAFT_4162 8.2e-233 812.8 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease LEHHPAIP_00505 349123.Lreu23DRAFT_4163 4.5e-100 370.5 Bacilli Bacteria 1VKIA@1239,4HNUJ@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family LEHHPAIP_00506 349123.Lreu23DRAFT_4164 1e-23 115.2 Lactobacillaceae Bacteria 1U6S6@1239,29PMB@1,30AJH@2,3F8E9@33958,4IGJQ@91061 NA|NA|NA LEHHPAIP_00507 349123.Lreu23DRAFT_3321 5.5e-33 146.4 Lactobacillaceae Bacteria 1UIMF@1239,2AQ9M@1,31FFI@2,3FBVB@33958,4ISND@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) LEHHPAIP_00508 1314.HKU360_01100 3.9e-237 827.0 Bacilli Bacteria 1V37H@1239,4HGN5@91061,COG3464@1,COG3464@2 NA|NA|NA L Transposase LEHHPAIP_00509 349123.Lreu23DRAFT_4801 3.7e-85 320.9 Lactobacillaceae Bacteria 1V45R@1239,3F7P2@33958,4HQY8@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin LEHHPAIP_00510 349123.Lreu23DRAFT_4802 2.8e-165 587.8 Lactobacillaceae Bacteria 1TPM1@1239,3F4IP@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S Oxidoreductase, aldo keto reductase family protein LEHHPAIP_00511 349123.Lreu23DRAFT_4803 3.8e-182 644.0 Lactobacillaceae 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F4EJ@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase LEHHPAIP_00512 349123.Lreu23DRAFT_4814 1.3e-98 366.3 Lactobacillaceae Bacteria 1TQXN@1239,3F4Y5@33958,4HBHT@91061,COG5434@1,COG5434@2 NA|NA|NA M Protein of unknown function (DUF3737) LEHHPAIP_00513 349123.Lreu23DRAFT_4815 1.1e-225 788.9 Lactobacillaceae 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I LEHHPAIP_00514 349123.Lreu23DRAFT_4816 3.1e-92 344.7 Lactobacillaceae Bacteria 1VAET@1239,3F6C2@33958,4HMQ8@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain LEHHPAIP_00515 349123.Lreu23DRAFT_4817 4e-224 783.9 Lactobacillaceae Bacteria 1V5MM@1239,3FBU1@33958,4ISZN@91061,COG5002@1,COG5002@2 NA|NA|NA T GHKL domain LEHHPAIP_00516 349123.Lreu23DRAFT_4818 9.9e-118 429.5 Lactobacillaceae Bacteria 1TQY9@1239,3FC94@33958,4HUBD@91061,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal LEHHPAIP_00517 557436.Lreu_1914 3.5e-158 564.3 Lactobacillaceae mleP3 ko:K07088 ko00000 Bacteria 1UY4N@1239,3FBIX@33958,4HEPU@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein LEHHPAIP_00518 1314.HKU360_01100 3.9e-237 827.0 Bacilli Bacteria 1V37H@1239,4HGN5@91061,COG3464@1,COG3464@2 NA|NA|NA L Transposase LEHHPAIP_00519 349123.Lreu23DRAFT_4689 2.4e-286 990.7 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol LEHHPAIP_00520 557436.Lreu_1794 7.6e-195 686.4 Lactobacillaceae Bacteria 1TSUK@1239,3F3S1@33958,4H9X7@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00521 349123.Lreu23DRAFT_4691 4.3e-86 323.9 Lactobacillaceae ymdB Bacteria 1TPCU@1239,3F6GV@33958,4HIHC@91061,COG2110@1,COG2110@2 NA|NA|NA S Macro domain protein LEHHPAIP_00522 557436.Lreu_1796 4.4e-98 364.0 Lactobacillaceae Bacteria 1VEKB@1239,3F84P@33958,4HH0D@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins LEHHPAIP_00523 557436.Lreu_1797 0.0 1266.1 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 LEHHPAIP_00524 557436.Lreu_1798 1.4e-47 195.3 Lactobacillaceae Bacteria 1U6RG@1239,2DKRV@1,30AIZ@2,3F8D1@33958,4IGIW@91061 NA|NA|NA LEHHPAIP_00525 557436.Lreu_1799 4.5e-236 823.5 Lactobacillaceae Bacteria 1VE6N@1239,3F556@33958,4HMSF@91061,COG3864@1,COG3864@2 NA|NA|NA S Putative metallopeptidase domain LEHHPAIP_00526 557436.Lreu_1800 3.4e-203 714.1 Lactobacillaceae 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1U8NZ@1239,3F53Z@33958,4HCYD@91061,COG0714@1,COG0714@2 NA|NA|NA S associated with various cellular activities LEHHPAIP_00527 557436.Lreu_1801 3.4e-120 437.6 Lactobacillaceae mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1E6@1239,3F59D@33958,4HG5E@91061,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family LEHHPAIP_00528 557436.Lreu_1802 5.9e-64 250.0 Lactobacillaceae yeaO Bacteria 1VABH@1239,3F715@33958,4HKI2@91061,COG3189@1,COG3189@2 NA|NA|NA S Protein of unknown function, DUF488 LEHHPAIP_00530 557436.Lreu_1804 3.4e-118 431.0 Lactobacillaceae yrkL ko:K11748 ko00000,ko02000 2.A.37.1.2 Bacteria 1V4UF@1239,3F6XY@33958,4HIR3@91061,COG2249@1,COG2249@2 NA|NA|NA S Flavodoxin-like fold LEHHPAIP_00531 349123.Lreu23DRAFT_4701 5.2e-53 213.4 Lactobacillaceae Bacteria 1VZZV@1239,2CCD8@1,348YF@2,3F79R@33958,4HZ8C@91061 NA|NA|NA LEHHPAIP_00532 97137.C821_00560 1.8e-16 93.6 Lactobacillaceae Bacteria 1VZSI@1239,29W71@1,30HS8@2,3F4M9@33958,4IEVP@91061 NA|NA|NA S Domain of unknown function (DUF4767) LEHHPAIP_00533 557436.Lreu_1807 1.2e-135 489.6 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TYDT@1239,3FBWF@33958,4HB9Z@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase LEHHPAIP_00534 349123.Lreu23DRAFT_4704 1.7e-47 194.9 Lactobacillaceae Bacteria 1U6JA@1239,29PGB@1,30AEG@2,3F80W@33958,4IGBU@91061 NA|NA|NA LEHHPAIP_00535 557436.Lreu_1809 8.9e-206 722.6 Lactobacillaceae nrnB ko:K07097 ko00000 Bacteria 1TQPZ@1239,3F5R4@33958,4HCSM@91061,COG2404@1,COG2404@2 NA|NA|NA S DHHA1 domain LEHHPAIP_00536 557436.Lreu_1810 1.8e-226 791.6 Lactobacillaceae Bacteria 1VK4A@1239,2EM25@1,33ERN@2,3F53P@33958,4HRGD@91061 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2325) LEHHPAIP_00537 557436.Lreu_1811 1.2e-247 862.1 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids LEHHPAIP_00538 349123.Lreu23DRAFT_4708 1.7e-105 388.7 Lactobacillaceae ko:K02395 ko00000,ko02035 Bacteria 1V7JY@1239,3F65T@33958,4I2AJ@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein LEHHPAIP_00539 557436.Lreu_1813 7.8e-143 513.1 Lactobacillaceae Bacteria 1V2HX@1239,3F3MV@33958,4HK25@91061,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV LEHHPAIP_00540 557436.Lreu_1814 1.9e-273 948.0 Lactobacillaceae ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein LEHHPAIP_00541 908339.HMPREF9265_1114 2.6e-17 94.4 Lactobacillaceae relB ko:K07473 ko00000,ko02048 Bacteria 1VJC4@1239,3F879@33958,4I1CX@91061,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin LEHHPAIP_00542 1423814.HMPREF0549_1473 6.4e-18 97.8 Lactobacillaceae Bacteria 1VEKB@1239,3F6AB@33958,4HNIW@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain LEHHPAIP_00543 1423815.BACR01000049_gene2333 4.5e-44 184.1 Lactobacillaceae arsB 1.20.4.1 ko:K03325,ko:K03741 ko00000,ko01000,ko02000 2.A.59 Bacteria 1TRMD@1239,3F5RE@33958,4HC8A@91061,COG0798@1,COG0798@2 NA|NA|NA P Sodium Bile acid symporter family LEHHPAIP_00544 525309.HMPREF0494_1082 2.7e-62 244.6 Lactobacillaceae arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1V3JW@1239,3F6GQ@33958,4HH49@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family LEHHPAIP_00545 257314.LJ_0230 1.8e-42 178.3 Lactobacillaceae arsR ko:K03892 ko00000,ko03000 Bacteria 1VEER@1239,3F77P@33958,4HPIB@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor LEHHPAIP_00546 525309.HMPREF0494_1081 1.6e-180 638.6 Lactobacillaceae arsB 1.20.4.1 ko:K03325,ko:K03741 ko00000,ko01000,ko02000 2.A.59 Bacteria 1TRMD@1239,3F5RE@33958,4HC8A@91061,COG0798@1,COG0798@2 NA|NA|NA P Sodium Bile acid symporter family LEHHPAIP_00547 525309.HMPREF0494_1082 8.2e-72 276.2 Lactobacillaceae arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1V3JW@1239,3F6GQ@33958,4HH49@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family LEHHPAIP_00548 525309.HMPREF0494_1083 9.4e-56 222.6 Lactobacillaceae cadX ko:K21903 ko00000,ko03000 Bacteria 1VBPB@1239,3F6GW@33958,4HMSR@91061,COG0640@1,COG0640@2 NA|NA|NA K Bacterial regulatory protein, arsR family LEHHPAIP_00549 525309.HMPREF0494_1084 2.8e-95 354.8 Lactobacillaceae cadD Bacteria 1V1RM@1239,3F4RK@33958,4HGMR@91061,COG4300@1,COG4300@2 NA|NA|NA P Cadmium resistance transporter LEHHPAIP_00550 1123302.KB904159_gene1259 1.1e-13 83.2 Firmicutes ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VK84@1239,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional LEHHPAIP_00551 908339.HMPREF9265_1212 3.9e-24 117.1 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase LEHHPAIP_00552 349123.Lreu23DRAFT_4713 1e-28 132.1 Bacilli WQ51_00220 ko:K07729 ko00000,ko03000 Bacteria 1VEKB@1239,4IPQ1@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain LEHHPAIP_00553 349123.Lreu23DRAFT_4714 7.4e-104 383.3 Lactobacillaceae Bacteria 1U48Z@1239,2EQR3@1,33IAY@2,3F8JT@33958,4IE0B@91061 NA|NA|NA S Protein of unknown function (DUF3278) LEHHPAIP_00555 349123.Lreu23DRAFT_4716 1.7e-73 283.1 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VFKC@1239,3F6HG@33958,4IFHN@91061,COG0791@1,COG0791@2 NA|NA|NA M PFAM NLP P60 protein LEHHPAIP_00556 557436.Lreu_1817 4.1e-181 640.6 Lactobacillaceae ABC-SBP ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter LEHHPAIP_00557 349123.Lreu23DRAFT_4718 1.1e-153 549.3 Lactobacillaceae XK27_08840 ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family LEHHPAIP_00558 349123.Lreu23DRAFT_4719 1.8e-136 491.9 Lactobacillaceae XK27_08845 ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F3NW@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ABC transporter, ATP-binding protein LEHHPAIP_00559 557436.Lreu_1820 5.1e-96 357.1 Lactobacillaceae Bacteria 1VUU3@1239,3F6NP@33958,4HVGH@91061,COG4300@1,COG4300@2 NA|NA|NA P Cadmium resistance transporter LEHHPAIP_00560 349123.Lreu23DRAFT_4721 9.9e-55 219.2 Lactobacillaceae Bacteria 1VA6G@1239,3F7DH@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator, ArsR family LEHHPAIP_00561 349123.Lreu23DRAFT_4722 9.5e-234 815.8 Lactobacillaceae mepA ko:K18908 M00705 ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 Bacteria 1TPFM@1239,3F3KX@33958,4HEHY@91061,COG0534@1,COG0534@2 NA|NA|NA V MATE efflux family protein LEHHPAIP_00562 557436.Lreu_1823 3.2e-55 220.7 Lactobacillaceae trxA ko:K03619,ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F7I4@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family LEHHPAIP_00563 349123.Lreu23DRAFT_4724 6.6e-131 473.4 Lactobacillaceae terC ko:K05794 ko00000 Bacteria 1UVIJ@1239,3F3WS@33958,4HEKW@91061,COG0861@1,COG0861@2 NA|NA|NA P membrane LEHHPAIP_00564 557436.Lreu_1825 1.1e-167 595.9 Lactobacillaceae rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TSM6@1239,3F50K@33958,4HA7M@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil LEHHPAIP_00565 349123.Lreu23DRAFT_4726 2.8e-168 597.8 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F4B8@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein LEHHPAIP_00566 557436.Lreu_1827 1.2e-279 968.4 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase LEHHPAIP_00567 349123.Lreu23DRAFT_4728 4.7e-241 840.1 Lactobacillaceae pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 ko:K03458,ko:K16169,ko:K16170 ko00000,ko02000 2.A.40,2.A.40.3.1,2.A.40.3.2 iSB619.SA_RS02140 Bacteria 1TNZZ@1239,3F3Y7@33958,4HBAM@91061,COG2233@1,COG2233@2 NA|NA|NA F xanthine permease LEHHPAIP_00568 349123.Lreu23DRAFT_4729 2.1e-247 861.3 Lactobacillaceae nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 1TQ3B@1239,3F3VX@33958,4HA18@91061,COG1757@1,COG1757@2 NA|NA|NA C Na H antiporter NhaC LEHHPAIP_00569 349123.Lreu23DRAFT_4730 3.6e-269 933.7 Lactobacillaceae Bacteria 1TQJ0@1239,3FCFJ@33958,4HBGX@91061,COG1288@1,COG1288@2 NA|NA|NA S C4-dicarboxylate anaerobic carrier LEHHPAIP_00570 218140.BPSY_1167 2.9e-70 271.9 Bifidobacteriales Bacteria 2GJGM@201174,4CZMJ@85004,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase LEHHPAIP_00571 525365.HMPREF0548_0486 4.6e-36 158.3 Lactobacillaceae ko:K19333 ko00000,ko03000 Bacteria 1V8YE@1239,3F4Y3@33958,4HIR8@91061,COG1414@1,COG1414@2 NA|NA|NA K Bacterial transcriptional regulator LEHHPAIP_00572 557436.Lreu_1837 2.7e-125 454.5 Lactobacillaceae pgm3 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQWQ@1239,3FC5M@33958,4HFDZ@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase family LEHHPAIP_00573 349123.Lreu23DRAFT_4732 1.2e-39 168.7 Lactobacillaceae Bacteria 1U9EP@1239,2900D@1,31CV8@2,3F8AF@33958,4IJHN@91061 NA|NA|NA LEHHPAIP_00574 349123.Lreu23DRAFT_4733 0.0 1396.7 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily LEHHPAIP_00575 557436.Lreu_1840 1.1e-206 725.7 Lactobacillaceae gldA 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 Bacteria 1TQFU@1239,3F4E4@33958,4HC8K@91061,COG0371@1,COG0371@2 NA|NA|NA C dehydrogenase LEHHPAIP_00576 349123.Lreu23DRAFT_3251 1.8e-113 415.2 Lactobacillaceae Bacteria 1TR6E@1239,3FBCW@33958,4HCAZ@91061,COG3547@1,COG3547@2 NA|NA|NA L transposase IS116 IS110 IS902 family protein LEHHPAIP_00577 349123.Lreu23DRAFT_3045 4.5e-82 310.5 Lactobacillaceae Bacteria 1TR6E@1239,3FBCW@33958,4HCAZ@91061,COG3547@1,COG3547@2 NA|NA|NA L transposase IS116 IS110 IS902 family protein LEHHPAIP_00578 557436.Lreu_1841 2.2e-38 164.5 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase LEHHPAIP_00579 557436.Lreu_1841 1.5e-63 249.2 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase LEHHPAIP_00580 557436.Lreu_1842 5.3e-215 753.4 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family LEHHPAIP_00581 349123.Lreu23DRAFT_4738 4.8e-97 360.5 Lactobacillaceae Bacteria 1U6NC@1239,29PIV@1,30AH0@2,3F86U@33958,4IGFC@91061 NA|NA|NA LEHHPAIP_00583 349123.Lreu23DRAFT_4740 1.3e-122 445.7 Lactobacillaceae yciB Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG LEHHPAIP_00584 349123.Lreu23DRAFT_4741 1.4e-259 901.7 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain LEHHPAIP_00585 557436.Lreu_1846 1.5e-107 395.6 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1V9F4@1239,3F5N4@33958,4IS4H@91061,COG0062@1,COG0062@2 NA|NA|NA H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX LEHHPAIP_00586 349123.Lreu23DRAFT_4743 3.6e-85 320.9 Lactobacillaceae Bacteria 1U7RY@1239,29QA9@1,30B9E@2,3FA3C@33958,4IHPA@91061 NA|NA|NA LEHHPAIP_00587 557436.Lreu_1848 1.5e-244 851.7 Lactobacillaceae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP3D@1239,3F3M3@33958,4HAM2@91061,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase LEHHPAIP_00588 557436.Lreu_1849 4.9e-213 746.9 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00589 349123.Lreu23DRAFT_4746 1e-100 372.9 Lactobacillaceae Bacteria 1U55V@1239,29DQI@1,300NC@2,3F4UQ@33958,4IEX6@91061 NA|NA|NA LEHHPAIP_00590 349123.Lreu23DRAFT_4747 1e-24 118.6 Lactobacillaceae Bacteria 1W51D@1239,29A0B@1,2ZX1X@2,3F8Q7@33958,4I0QW@91061 NA|NA|NA LEHHPAIP_00591 349123.Lreu23DRAFT_4748 6.7e-173 613.2 Lactobacillaceae scrR ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4JE@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family LEHHPAIP_00592 557436.Lreu_1924 1.1e-192 679.1 Lactobacillaceae Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase LEHHPAIP_00593 349123.Lreu23DRAFT_4830 6e-94 350.1 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F3K3@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family LEHHPAIP_00594 349123.Lreu23DRAFT_4831 1.8e-98 365.2 Lactobacillaceae yhiD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V409@1239,3F3QE@33958,4HK8H@91061,COG1285@1,COG1285@2 NA|NA|NA S MgtC family LEHHPAIP_00595 557436.Lreu_1927 7e-54 216.5 Lactobacillaceae Bacteria 1TQC2@1239,3FCAT@33958,4HHUH@91061,COG4832@1,COG4832@2 NA|NA|NA S GyrI-like small molecule binding domain LEHHPAIP_00596 349123.Lreu23DRAFT_4834 3e-125 454.5 Lactobacillaceae ybhF_2 ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQKM@1239,3F3VV@33958,4HBUK@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system LEHHPAIP_00597 349123.Lreu23DRAFT_4835 3.8e-183 647.5 Lactobacillaceae ybhR ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQG7@1239,3F40D@33958,4H9MK@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC transporter LEHHPAIP_00598 349123.Lreu23DRAFT_4836 1.2e-90 339.3 Lactobacillaceae Bacteria 1V3R8@1239,3FCEK@33958,4HQ5Z@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family LEHHPAIP_00599 557436.Lreu_1928 7.3e-110 403.3 Lactobacillaceae Bacteria 1VBTT@1239,2E7EK@1,331XM@2,3F4W0@33958,4HMT5@91061 NA|NA|NA S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) LEHHPAIP_00600 557436.Lreu_1929 3.2e-50 204.1 Lactobacillaceae azlD Bacteria 1V9YS@1239,3F8HI@33958,4HJID@91061,COG1687@1,COG1687@2 NA|NA|NA E Branched-chain amino acid transport LEHHPAIP_00601 557436.Lreu_1930 5.3e-119 433.7 Lactobacillaceae azlC Bacteria 1TP8P@1239,3F5PP@33958,4HE6G@91061,COG1296@1,COG1296@2 NA|NA|NA E azaleucine resistance protein AzlC LEHHPAIP_00602 349123.Lreu23DRAFT_4841 6.9e-259 899.4 Lactobacillaceae Bacteria 1TPS5@1239,3F55Z@33958,4HD5A@91061,COG1167@1,COG1167@2 NA|NA|NA K Aminotransferase class I and II LEHHPAIP_00603 349123.Lreu23DRAFT_4842 3.2e-92 344.4 Lactobacillaceae Bacteria 1TQ6G@1239,3F4DW@33958,4HC54@91061,COG1574@1,COG1574@2 NA|NA|NA S amidohydrolase LEHHPAIP_00604 557436.Lreu_1932 2.8e-79 301.2 Lactobacillaceae Bacteria 1TQ6G@1239,3F4DW@33958,4HC54@91061,COG1574@1,COG1574@2 NA|NA|NA S amidohydrolase LEHHPAIP_00605 557436.Lreu_0441 5.5e-105 387.1 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 LEHHPAIP_00606 1203076.CAKF01000017_gene1686 2.1e-37 161.4 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region LEHHPAIP_00607 1203076.CAKF01000017_gene1686 3.3e-121 441.0 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region LEHHPAIP_00608 557436.Lreu_1934 9.2e-49 199.1 Lactobacillaceae 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1V3V3@1239,3F72S@33958,4IFUY@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase GNAT family LEHHPAIP_00609 349123.Lreu23DRAFT_4844 2.5e-14 83.6 Lactobacillaceae 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1V3V3@1239,3F72S@33958,4IFUY@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase GNAT family LEHHPAIP_00610 349123.Lreu23DRAFT_4845 1.7e-113 415.2 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7H9@1239,3F56W@33958,4HMGQ@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family LEHHPAIP_00611 557436.Lreu_1936 1.4e-247 861.7 Lactobacillaceae yxbA 6.3.1.12 ko:K17810 ko00000,ko01000 Bacteria 1TQPN@1239,3F3S7@33958,4HAB0@91061,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp enzyme LEHHPAIP_00612 349123.Lreu23DRAFT_4847 1.7e-290 1004.6 Lactobacillaceae murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,3F3UE@33958,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan LEHHPAIP_00613 557436.Lreu_1938 0.0 1315.8 Lactobacillaceae asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRPB@1239,3F3NT@33958,4HAIP@91061,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase LEHHPAIP_00614 349123.Lreu23DRAFT_4849 0.0 1271.9 Lactobacillaceae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,3F454@33958,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 LEHHPAIP_00615 349123.Lreu23DRAFT_4850 2.8e-252 877.5 Lactobacillaceae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1TPJF@1239,3F3WA@33958,4HA06@91061,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 LEHHPAIP_00616 349123.Lreu23DRAFT_4851 1.1e-130 472.6 Lactobacillaceae jag ko:K06346 ko00000 Bacteria 1V3IN@1239,3F5WG@33958,4HHHU@91061,COG1847@1,COG1847@2 NA|NA|NA S R3H domain protein LEHHPAIP_00617 349123.Lreu23DRAFT_4852 1.7e-129 468.8 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TQ0J@1239,3F3SD@33958,4HB3J@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins LEHHPAIP_00618 349123.Lreu23DRAFT_4853 2e-58 231.5 Lactobacillaceae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1VA78@1239,3F6GS@33958,4HKG6@91061,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme LEHHPAIP_00619 1423814.HMPREF0549_1042 3.4e-14 83.2 Lactobacillaceae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK90@1239,3F81W@33958,4HR2Z@91061,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family LEHHPAIP_00620 349123.Lreu23DRAFT_4855 1.1e-250 872.1 Lactobacillaceae dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1TPV7@1239,3F3YA@33958,4H9MW@91061,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids LEHHPAIP_00621 349123.Lreu23DRAFT_4856 2.1e-205 721.5 Lactobacillaceae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQ7J@1239,3F3ZQ@33958,4H9TF@91061,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria LEHHPAIP_00622 349123.Lreu23DRAFT_4857 4.9e-34 149.8 Lactobacillaceae yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 1VEJ2@1239,3F803@33958,4HNMC@91061,COG2501@1,COG2501@2 NA|NA|NA S S4 domain protein YaaA LEHHPAIP_00623 349123.Lreu23DRAFT_4858 1.3e-204 718.8 Lactobacillaceae recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TP9U@1239,3F3Q1@33958,4HA0W@91061,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP LEHHPAIP_00624 349123.Lreu23DRAFT_4859 0.0 1285.4 Lactobacillaceae gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 1TQ0R@1239,3F48M@33958,4H9Y6@91061,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner LEHHPAIP_00625 349123.Lreu23DRAFT_4860 0.0 1460.3 Lactobacillaceae gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 1TP2Z@1239,3F3YM@33958,4HAHY@91061,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner LEHHPAIP_00626 349123.Lreu23DRAFT_4861 1.2e-48 198.7 Lactobacillaceae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA18@1239,3F6ZY@33958,4HKHD@91061,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA LEHHPAIP_00627 349123.Lreu23DRAFT_4862 3.1e-77 294.7 Lactobacillaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,3F66N@33958,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism LEHHPAIP_00628 349123.Lreu23DRAFT_4863 1.6e-35 154.8 Lactobacillaceae rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 1V9XS@1239,3F7CY@33958,4HKCC@91061,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit LEHHPAIP_00629 944562.HMPREF9102_0612 1.3e-75 289.3 Lactobacillaceae deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4,5.4.2.8 ko:K01619,ko:K01840 ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130 M00114 R01066,R01818 RC00408,RC00436,RC00437 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAJ@1239,3F4M3@33958,4HAAJ@91061,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate LEHHPAIP_00630 908339.HMPREF9265_0006 6.5e-18 96.3 Lactobacillaceae deoR GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05346 ko00000,ko03000 Bacteria 1TPUB@1239,3F4PP@33958,4HCAR@91061,COG2390@1,COG2390@2 NA|NA|NA K sugar-binding domain protein LEHHPAIP_00631 575594.ACOH01000028_gene512 1.1e-52 213.0 Lactobacillaceae deoR GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05346 ko00000,ko03000 Bacteria 1TPUB@1239,3F4PP@33958,4HCAR@91061,COG2390@1,COG2390@2 NA|NA|NA K sugar-binding domain protein LEHHPAIP_00632 557436.Lreu_0010 0.0 1313.1 Lactobacillaceae yybT Bacteria 1TPGP@1239,3F3TY@33958,4HBVH@91061,COG3887@1,COG3887@2 NA|NA|NA T signaling protein consisting of a modified GGDEF domain and a DHH domain LEHHPAIP_00633 349123.Lreu23DRAFT_4865 2e-74 285.0 Lactobacillaceae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6QG@1239,3F68P@33958,4HIKJ@91061,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA LEHHPAIP_00634 557436.Lreu_0012 1.5e-234 818.5 Lactobacillaceae dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1TPCT@1239,3F4MW@33958,4H9Y8@91061,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication LEHHPAIP_00635 349123.Lreu23DRAFT_4867 2.6e-206 724.5 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00636 349123.Lreu23DRAFT_4868 9.1e-61 239.2 Lactobacillaceae Bacteria 1U690@1239,29P85@1,30A67@2,3F7C2@33958,4IG05@91061 NA|NA|NA LEHHPAIP_00637 557436.Lreu_0015 1.4e-156 558.9 Lactobacillaceae Bacteria 1TQQR@1239,3F59Q@33958,4HDT2@91061,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate nucleotide phosphotransferase, PPK2 family LEHHPAIP_00638 908339.HMPREF9265_2070 3.8e-38 164.5 Lactobacillaceae Z012_01130 Bacteria 1UZBJ@1239,3F566@33958,4HM3C@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family LEHHPAIP_00639 1033837.WANG_1871 3e-71 275.4 Lactobacillaceae Z012_01130 Bacteria 1UZBJ@1239,3F566@33958,4HM3C@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family LEHHPAIP_00641 349123.Lreu23DRAFT_4871 1.8e-72 278.5 Lactobacillaceae Bacteria 1VMZX@1239,3F7JV@33958,4HMTC@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein LEHHPAIP_00642 349123.Lreu23DRAFT_4872 2.9e-307 1060.4 Lactobacillaceae lmrA 3.6.3.44 ko:K06147,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21 Bacteria 1TSY4@1239,3FC4S@33958,4HAJQ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter LEHHPAIP_00644 557436.Lreu_0019 3.1e-130 471.1 Lactobacillaceae Bacteria 1TPQG@1239,3F4FB@33958,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator LEHHPAIP_00645 349123.Lreu23DRAFT_4874 0.0 1171.4 Lactobacillaceae vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F45G@33958,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase LEHHPAIP_00646 557436.Lreu_0021 2e-244 851.3 Lactobacillaceae yycH Bacteria 1V32Y@1239,3F4HR@33958,4HG2Q@91061,COG4863@1,COG4863@2 NA|NA|NA S YycH protein LEHHPAIP_00647 349123.Lreu23DRAFT_4876 7.8e-149 533.1 Lactobacillaceae yycI Bacteria 1V1FW@1239,3F3PV@33958,4HFWZ@91061,COG4853@1,COG4853@2 NA|NA|NA S YycH protein LEHHPAIP_00648 349123.Lreu23DRAFT_4877 5.9e-154 550.1 Lactobacillaceae vicX 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ8E@1239,3F3S4@33958,4HAKD@91061,COG1235@1,COG1235@2 NA|NA|NA S domain protein LEHHPAIP_00649 557436.Lreu_0024 6.6e-216 756.5 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease LEHHPAIP_00650 557436.Lreu_0025 1e-87 329.3 Lactobacillaceae pgpA 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 1V3I0@1239,3F6QT@33958,4HH4Y@91061,COG1267@1,COG1267@2 NA|NA|NA I Phosphatidylglycerophosphatase A LEHHPAIP_00651 349123.Lreu23DRAFT_4880 1.5e-175 622.1 Lactobacillaceae ABC-SBP ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter LEHHPAIP_00652 349123.Lreu23DRAFT_4881 4.7e-88 330.5 Lactobacillaceae rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1V3JM@1239,3F3YX@33958,4HFP8@91061,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA LEHHPAIP_00654 557436.Lreu_0029 2.9e-96 357.8 Lactobacillaceae Bacteria 1TP8I@1239,3FBB2@33958,4HF88@91061,COG0431@1,COG0431@2 NA|NA|NA S reductase LEHHPAIP_00655 557436.Lreu_0030 4.9e-226 790.0 Lactobacillaceae dhaT 1.1.1.1,1.1.1.202 ko:K00086,ko:K13954 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02377,R03119,R04880,R05233,R05234,R06917,R06927 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649 ko00000,ko00001,ko01000 iYL1228.KPN_03491 Bacteria 1TPB4@1239,3F4SZ@33958,4HAPA@91061,COG1454@1,COG1454@2 NA|NA|NA C Dehydrogenase LEHHPAIP_00656 349123.Lreu23DRAFT_4885 1.3e-154 552.4 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport LEHHPAIP_00657 557436.Lreu_0032 1.9e-149 535.0 Lactobacillaceae Bacteria 1V5HJ@1239,3FBBB@33958,4HMUV@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase-like domain LEHHPAIP_00658 557436.Lreu_0033 4.1e-147 527.3 Lactobacillaceae proC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0899,iIT341.HP1158 Bacteria 1UI7P@1239,3F769@33958,4HEZA@91061,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline LEHHPAIP_00659 349123.Lreu23DRAFT_4888 4.4e-258 896.7 Lactobacillaceae gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family LEHHPAIP_00660 557436.Lreu_0035 2.8e-143 515.0 Lactobacillaceae bacG ko:K02005 ko00000 Bacteria 1TT2M@1239,3F5MV@33958,4HG99@91061,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family LEHHPAIP_00661 557436.Lreu_0036 2.8e-128 464.5 Lactobacillaceae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBJ@1239,3F4CA@33958,4HFUH@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter LEHHPAIP_00662 349123.Lreu23DRAFT_4892 7.8e-214 749.6 Lactobacillaceae bacI ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUU@1239,3FB5I@33958,4HATE@91061,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain LEHHPAIP_00663 349123.Lreu23DRAFT_4893 3.8e-22 111.7 Lactobacillaceae Bacteria 1U8BH@1239,29QMQ@1,30BMC@2,3FASY@33958,4II9H@91061 NA|NA|NA LEHHPAIP_00664 557436.Lreu_0040 4.8e-260 903.3 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain LEHHPAIP_00666 349123.Lreu23DRAFT_4897 1.6e-08 65.5 Lactobacillaceae 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UYTM@1239,3F7GX@33958,4HIRT@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain LEHHPAIP_00667 334390.LAF_1659 8.7e-54 216.1 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model LEHHPAIP_00668 525309.HMPREF0494_1313 3.6e-85 320.9 Lactobacillaceae Bacteria 1U5C6@1239,3F5HT@33958,4IF3D@91061,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein LEHHPAIP_00669 1158614.I592_01171 4e-119 434.1 Enterococcaceae hisK 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V77D@1239,4AZQU@81852,4HHQX@91061,COG1387@1,COG1387@2 NA|NA|NA E Histidinol phosphatase and related hydrolases of the PHP family LEHHPAIP_00672 557436.Lreu_0042 5e-75 287.0 Lactobacillaceae osmC Bacteria 1V3B2@1239,3F6SM@33958,4HI09@91061,COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein LEHHPAIP_00673 349123.Lreu23DRAFT_4904 8.3e-174 616.3 Lactobacillaceae ldhD 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family LEHHPAIP_00674 349123.Lreu23DRAFT_4905 1.8e-215 755.0 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase LEHHPAIP_00675 349123.Lreu23DRAFT_4906 7.8e-32 142.5 Lactobacillaceae Bacteria 1VZ0G@1239,2BZQ9@1,3490W@2,3F7PN@33958,4HY72@91061 NA|NA|NA LEHHPAIP_00676 349123.Lreu23DRAFT_4907 0.0 1231.5 Lactobacillaceae clpL ko:K04086 ko00000,ko03110 Bacteria 1TPMU@1239,3F43D@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O associated with various cellular activities LEHHPAIP_00678 349123.Lreu23DRAFT_4910 3.1e-104 384.4 Lactobacillaceae wecD3 Bacteria 1VC3M@1239,3FBUJ@33958,4IS49@91061,COG0454@1,COG0456@2 NA|NA|NA K PFAM GCN5-related N-acetyltransferase LEHHPAIP_00679 349123.Lreu23DRAFT_4911 5.5e-283 979.5 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol LEHHPAIP_00680 349123.Lreu23DRAFT_4912 0.0 2412.9 Lactobacillaceae rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.3,3.6.4.12 ko:K01153,ko:K16899 ko00000,ko01000,ko02048,ko03400 Bacteria 1TQJW@1239,3F3RS@33958,4HAY6@91061,COG3857@1,COG3857@2 NA|NA|NA L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity LEHHPAIP_00681 557436.Lreu_0050 0.0 2676.4 Lactobacillaceae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,3F3Z0@33958,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A LEHHPAIP_00682 349123.Lreu23DRAFT_4914 4.3e-172 610.5 Lactobacillaceae malR ko:K02529 ko00000,ko03000 Bacteria 1TPZM@1239,3F4TM@33958,4H9ZT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family LEHHPAIP_00683 349123.Lreu23DRAFT_4915 5.7e-214 750.0 Lactobacillaceae phbA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034308,GO:0034309,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046165,GO:0046395,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:0072329,GO:1901575,GO:1901576,GO:1901615,GO:1901617 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 iSSON_1240.SSON_3004 Bacteria 1TP07@1239,3F3Q5@33958,4H9RJ@91061,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family LEHHPAIP_00684 349123.Lreu23DRAFT_4916 1.1e-256 892.1 Lactobacillaceae malT ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator LEHHPAIP_00685 557436.Lreu_0054 0.0 1561.2 Lactobacillaceae mapA 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 R01555 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic LEHHPAIP_00686 557436.Lreu_0055 1.6e-120 438.7 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3F4ST@33958,4HF3K@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase LEHHPAIP_00687 557436.Lreu_0056 1e-71 276.2 Lactobacillaceae Bacteria 1U6RP@1239,2AG18@1,3165B@2,3F8DG@33958,4IGJ4@91061 NA|NA|NA LEHHPAIP_00688 1423814.HMPREF0549_0988 3.7e-87 327.8 Lactobacillaceae 2.7.6.5 ko:K00951,ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F518@33958,4IQWD@91061,COG2357@1,COG2357@2 NA|NA|NA T Region found in RelA / SpoT proteins LEHHPAIP_00689 557436.Lreu_0058 3.3e-118 431.0 Lactobacillaceae Bacteria 1TPU2@1239,3F53G@33958,4HG2E@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator LEHHPAIP_00690 557436.Lreu_0059 3.1e-226 790.8 Lactobacillaceae sptS 2.7.13.3 ko:K11328 ko02020,map02020 M00464 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UHQH@1239,3F4JY@33958,4HAHG@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase LEHHPAIP_00691 557436.Lreu_0060 4.7e-216 756.9 Lactobacillaceae yfeO GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03281 ko00000 2.A.49 Bacteria 1UZ4F@1239,3F605@33958,4HDXG@91061,COG0038@1,COG0038@2 NA|NA|NA P Voltage gated chloride channel LEHHPAIP_00692 349123.Lreu23DRAFT_4919 5.6e-258 896.3 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family LEHHPAIP_00693 557436.Lreu_0063 8.6e-136 489.6 Lactobacillaceae puuD ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F4PK@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S peptidase C26 LEHHPAIP_00694 557436.Lreu_0064 5.9e-168 596.7 Lactobacillaceae yvgN Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase LEHHPAIP_00695 557436.Lreu_0065 0.0 1137.5 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UGF1@1239,3FC1C@33958,4HBM4@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C Membrane domain of glycerophosphoryl diester phosphodiesterase LEHHPAIP_00696 557436.Lreu_0066 1.5e-86 325.5 Lactobacillaceae hmpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1VBJP@1239,3FB41@33958,4HNRQ@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component LEHHPAIP_00697 557436.Lreu_0067 2e-263 914.4 Lactobacillaceae nox Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase LEHHPAIP_00698 557436.Lreu_0068 3.8e-187 660.6 Lactobacillaceae guaC 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS06660 Bacteria 1TNYF@1239,3F45K@33958,4HA55@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides LEHHPAIP_00699 349123.Lreu23DRAFT_4927 1.4e-253 881.7 Lactobacillaceae purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4C@1239,3F3RQ@33958,4H9YT@91061,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP LEHHPAIP_00700 557436.Lreu_0070 3.9e-78 298.1 Lactobacillaceae Bacteria 1W566@1239,2CG78@1,2ZKRC@2,3F6AU@33958,4I124@91061 NA|NA|NA LEHHPAIP_00701 349123.Lreu23DRAFT_4929 4.1e-95 354.0 Lactobacillaceae pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 1V3GV@1239,3F4SR@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant LEHHPAIP_00703 557436.Lreu_0076 9.3e-13 78.2 Lactobacillaceae steT_1 Bacteria 1UZNT@1239,3F3SX@33958,4HFMI@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00704 349123.Lreu23DRAFT_4931 4.3e-13 80.1 Lactobacillaceae Bacteria 1U5TP@1239,3F6HI@33958,4IFHQ@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator, TetR family LEHHPAIP_00705 349123.Lreu23DRAFT_4931 1e-73 282.7 Lactobacillaceae Bacteria 1U5TP@1239,3F6HI@33958,4IFHQ@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator, TetR family LEHHPAIP_00706 349123.Lreu23DRAFT_4932 8.3e-72 276.2 Lactobacillaceae Bacteria 1VFXH@1239,2DNYJ@1,32ZT4@2,3F6B5@33958,4HPEG@91061 NA|NA|NA LEHHPAIP_00707 349123.Lreu23DRAFT_4933 3.1e-268 930.6 Lactobacillaceae tagE3 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1V09I@1239,3FBDH@33958,4HDDD@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 LEHHPAIP_00708 349123.Lreu23DRAFT_4934 1.4e-270 938.3 Lactobacillaceae tagE2 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1VSNK@1239,3F4VP@33958,4HU8G@91061,COG0438@1,COG0438@2 NA|NA|NA M Poly(Glycerol-phosphate) alpha-glucosyltransferase LEHHPAIP_00709 349123.Lreu23DRAFT_4935 3e-280 970.7 Bacilli Bacteria 1TSAS@1239,4HIT7@91061,COG4932@1,COG4932@2 NA|NA|NA M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes LEHHPAIP_00710 349123.Lreu23DRAFT_4936 0.0 1168.7 Lactobacillaceae malL 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein LEHHPAIP_00711 349123.Lreu23DRAFT_4937 7.5e-266 922.5 Lactobacillaceae ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator LEHHPAIP_00712 557436.Lreu_0085 0.0 2050.4 Lactobacillaceae carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase LEHHPAIP_00713 557436.Lreu_0086 1.1e-206 725.7 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain LEHHPAIP_00714 557436.Lreu_0087 6.1e-260 902.9 Lactobacillaceae ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator LEHHPAIP_00715 557436.Lreu_0088 8.9e-176 622.9 Lactobacillaceae ko:K02529 ko00000,ko03000 Bacteria 1TRFH@1239,3F5CG@33958,4HBNT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family LEHHPAIP_00716 557436.Lreu_0089 7.2e-264 916.0 Lactobacillaceae rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP4H@1239,3F4GQ@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family LEHHPAIP_00717 557436.Lreu_0090 5.4e-101 373.6 Lactobacillaceae nqr 1.5.1.36 ko:K22393 ko00740,ko01100,map00740,map01100 R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 Bacteria 1TPRA@1239,3F44U@33958,4HDA5@91061,COG0431@1,COG0431@2 NA|NA|NA S reductase LEHHPAIP_00718 557436.Lreu_0091 1.2e-198 699.1 Lactobacillaceae XK27_09615 ko:K09155 ko00000 Bacteria 1TPRA@1239,3F44U@33958,4HDA5@91061,COG0431@1,COG0431@2,COG2461@1,COG2461@2 NA|NA|NA S reductase LEHHPAIP_00719 557436.Lreu_0092 1.7e-176 625.2 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3FB4A@33958,4HDFE@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein LEHHPAIP_00720 557436.Lreu_1304 1.6e-54 219.2 Lactobacillaceae Bacteria 1V759@1239,3F58J@33958,4HK5F@91061,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) LEHHPAIP_00721 557436.Lreu_1305 2.5e-77 294.7 Lactobacillaceae Bacteria 1V7RA@1239,2DMPJ@1,32SWG@2,3F7QU@33958,4IG6C@91061 NA|NA|NA S Psort location Cytoplasmic, score LEHHPAIP_00722 349123.Lreu23DRAFT_4167 4.6e-285 986.5 Lactobacillaceae dinB 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3FCBJ@33958,4HFGA@91061,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family C-terminal domain LEHHPAIP_00723 349123.Lreu23DRAFT_4168 2e-76 291.6 Lactobacillaceae hsp ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3FB63@33958,4HIUZ@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family LEHHPAIP_00724 349123.Lreu23DRAFT_4169 4.5e-152 543.9 Lactobacillaceae yeaE Bacteria 1TPM1@1239,3FB4U@33958,4HBIQ@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo keto LEHHPAIP_00725 349123.Lreu23DRAFT_4170 5.3e-237 826.6 Lactobacillaceae preA GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0051536,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 ko:K02572,ko:K02573,ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_2293 Bacteria 1TRPI@1239,3FC4Q@33958,4HBRG@91061,COG0167@1,COG0167@2,COG1146@1,COG1146@2 NA|NA|NA C 4Fe-4S dicluster domain LEHHPAIP_00726 349123.Lreu23DRAFT_4171 4.7e-235 820.1 Lactobacillaceae preT GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0051536,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 iECED1_1282.ECED1_2593,iECO103_1326.ECO103_2621,iLF82_1304.LF82_3021 Bacteria 1TR18@1239,3F5CE@33958,4HFCY@91061,COG0493@1,COG0493@2 NA|NA|NA E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster LEHHPAIP_00727 349123.Lreu23DRAFT_4172 1.5e-146 525.4 Lactobacillaceae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,3F4GK@33958,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III LEHHPAIP_00728 557436.Lreu_1312 1.3e-88 332.8 Lactobacillaceae lytE Bacteria 1V773@1239,3F3JQ@33958,4HIJG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein LEHHPAIP_00729 557436.Lreu_1313 0.0 1133.6 Lactobacillaceae oppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TS8Q@1239,3F4T6@33958,4HCZ1@91061,COG0444@1,COG0444@2 NA|NA|NA EP Psort location Cytoplasmic, score LEHHPAIP_00730 349123.Lreu23DRAFT_4175 2e-42 179.5 Lactobacillaceae lytE Bacteria 1V773@1239,3F3JQ@33958,4HIJG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein LEHHPAIP_00731 557436.Lreu_1315 9.8e-158 562.8 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1U5WR@1239,3F6MK@33958,4IFK7@91061,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) LEHHPAIP_00732 349123.Lreu23DRAFT_4177 7.6e-111 406.4 Lactobacillaceae nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 1V1HG@1239,3F46H@33958,4HGJ9@91061,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine LEHHPAIP_00733 557436.Lreu_1317 0.0 1538.5 Lactobacillaceae nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 1TR9K@1239,3F435@33958,4HBIY@91061,COG1328@1,COG1328@2 NA|NA|NA F Ribonucleoside-triphosphate reductase LEHHPAIP_00734 349123.Lreu23DRAFT_4179 1.1e-57 229.2 Lactobacillaceae lmrB ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00735 557436.Lreu_1318 2.2e-152 545.0 Lactobacillaceae lmrB ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_00736 557436.Lreu_1319 4.1e-98 364.0 Lactobacillaceae 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1VEW7@1239,3FCFM@33958,4HQMJ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain LEHHPAIP_00737 349123.Lreu23DRAFT_3975 6.8e-154 550.1 Lactobacillaceae ko:K07273 ko00000 Bacteria 1UV96@1239,3F7BC@33958,4IFZR@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 LEHHPAIP_00738 349123.Lreu23DRAFT_3976 5.2e-57 227.3 Lactobacillaceae Bacteria 1U6IX@1239,29PG3@1,30AE8@2,3F80H@33958,4IGBF@91061 NA|NA|NA S Bacteriophage holin of superfamily 6 (Holin_LLH) LEHHPAIP_00739 1567453.A0A0A1ENR5_9CAUD 8.4e-34 149.8 Siphoviridae Viruses 4QFX5@10239,4QMC7@10699,4QRBG@28883 NA|NA|NA LEHHPAIP_00740 349123.Lreu23DRAFT_4196 4.3e-131 476.5 Lactobacillaceae Bacteria 1V5YB@1239,3FBEX@33958,4IPZC@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase LEHHPAIP_00742 349123.Lreu23DRAFT_4198 0.0 1629.4 Lactobacillaceae Bacteria 1V80R@1239,3FC11@33958,4HJEY@91061,COG4926@1,COG4926@2 NA|NA|NA M Prophage endopeptidase tail LEHHPAIP_00743 349123.Lreu23DRAFT_4199 8.9e-147 526.2 Lactobacillaceae Bacteria 1VHE0@1239,3F6A1@33958,4HNTT@91061,COG4722@1,COG4722@2 NA|NA|NA S phage tail LEHHPAIP_00744 349123.Lreu23DRAFT_4200 2.6e-259 901.7 Lactobacillaceae sca1 Bacteria 1TQ28@1239,3F5K4@33958,4HAFE@91061,COG1196@1,COG1196@2,COG5412@1,COG5412@2 NA|NA|NA D Phage tail tape measure protein LEHHPAIP_00745 349123.Lreu23DRAFT_4201 1e-60 239.2 Lactobacillaceae Bacteria 1VKIN@1239,2EHS8@1,33BHZ@2,3F7N3@33958,4HR6E@91061 NA|NA|NA LEHHPAIP_00746 349123.Lreu23DRAFT_4202 2.6e-55 221.1 Lactobacillaceae Bacteria 1VGCP@1239,2EBTF@1,335T1@2,3F84Y@33958,4HP3P@91061 NA|NA|NA S Phage tail assembly chaperone protein, TAC LEHHPAIP_00747 349123.Lreu23DRAFT_4203 7.7e-103 379.8 Lactobacillaceae Bacteria 1VUVY@1239,2F0XZ@1,33TZM@2,3F76N@33958,4HVU9@91061 NA|NA|NA S Phage tail tube protein LEHHPAIP_00748 908339.HMPREF9265_0939 8.4e-21 106.7 Lactobacillaceae Bacteria 1VEQW@1239,2DQ37@1,334JI@2,3FBQW@33958,4IS04@91061 NA|NA|NA S Protein of unknown function (DUF3168) LEHHPAIP_00749 349123.Lreu23DRAFT_4205 4.2e-68 263.8 Lactobacillaceae Bacteria 1VFPA@1239,2CIV5@1,32ZS6@2,3F81G@33958,4HQWN@91061 NA|NA|NA S Bacteriophage HK97-gp10, putative tail-component LEHHPAIP_00750 349123.Lreu23DRAFT_4206 7.9e-46 189.5 Lactobacillaceae Bacteria 1VIHK@1239,2E86K@1,332JW@2,3F8A2@33958,4HZJB@91061 NA|NA|NA LEHHPAIP_00751 349123.Lreu23DRAFT_4207 2.1e-64 251.5 Lactobacillaceae Bacteria 1VN9C@1239,2EKJJ@1,33E9D@2,3F7K9@33958,4HR20@91061 NA|NA|NA S Phage gp6-like head-tail connector protein LEHHPAIP_00752 349123.Lreu23DRAFT_4208 1.1e-153 549.3 Bacilli Bacteria 1V47S@1239,2C2F4@1,305QN@2,4HIHZ@91061 NA|NA|NA LEHHPAIP_00753 349123.Lreu23DRAFT_4209 2.6e-101 374.8 Lactobacillaceae Bacteria 1VEET@1239,2DNT1@1,32YZX@2,3F7QQ@33958,4HQ00@91061 NA|NA|NA S Domain of unknown function (DUF4355) LEHHPAIP_00755 349123.Lreu23DRAFT_4211 2e-173 615.9 Lactobacillaceae Bacteria 1UV98@1239,3FB8J@33958,4HSNW@91061,COG2369@1,COG2369@2 NA|NA|NA S Phage Mu protein F like protein LEHHPAIP_00756 349123.Lreu23DRAFT_4212 3.3e-272 943.7 Lactobacillaceae Bacteria 1TR67@1239,2DB9U@1,2Z7Z6@2,3FB8U@33958,4HCTZ@91061 NA|NA|NA S Phage portal protein LEHHPAIP_00757 349123.Lreu23DRAFT_4213 1.1e-244 852.0 Lactobacillaceae ko:K06909 ko00000 Bacteria 1TRQP@1239,3FB8E@33958,4HDMY@91061,COG1783@1,COG1783@2 NA|NA|NA S Phage terminase, large subunit LEHHPAIP_00759 349123.Lreu23DRAFT_4214 1.6e-60 238.8 Lactobacillaceae ko:K07474 ko00000 Bacteria 1VAD9@1239,3F6ZJ@33958,4HXMG@91061,COG3728@1,COG3728@2 NA|NA|NA L Terminase small subunit LEHHPAIP_00761 349123.Lreu23DRAFT_4217 4.7e-79 300.4 Bacilli arpU Bacteria 1W30Q@1239,2DPRG@1,3333C@2,4I13H@91061 NA|NA|NA S Phage transcriptional regulator, ArpU family LEHHPAIP_00768 349123.Lreu23DRAFT_4223 8e-60 236.1 Lactobacillaceae Bacteria 1VA3C@1239,2DJ23@1,32UC6@2,3F7VB@33958,4HPYG@91061 NA|NA|NA S VRR_NUC LEHHPAIP_00770 349123.Lreu23DRAFT_4225 2.6e-233 814.3 Lactobacillaceae Bacteria 1TQNX@1239,3F4EZ@33958,4HCHZ@91061,COG5545@1,COG5545@2 NA|NA|NA S Virulence-associated protein E LEHHPAIP_00771 349123.Lreu23DRAFT_4226 1.9e-136 491.9 Lactobacillaceae Bacteria 1V4PM@1239,3F3RI@33958,4HHZK@91061,COG3378@1,COG3378@2 NA|NA|NA S Bifunctional DNA primase/polymerase, N-terminal LEHHPAIP_00772 349123.Lreu23DRAFT_4227 1.7e-93 348.6 Lactobacillaceae Bacteria 1VDGZ@1239,2C0B0@1,32WZE@2,3F79D@33958,4HMDG@91061 NA|NA|NA LEHHPAIP_00773 349123.Lreu23DRAFT_4228 7.1e-141 506.5 Lactobacillaceae Bacteria 1UYIX@1239,3F5K8@33958,4HF6W@91061,COG2887@1,COG2887@2 NA|NA|NA L AAA domain LEHHPAIP_00774 349123.Lreu23DRAFT_4229 4e-259 900.2 Lactobacillaceae res Bacteria 1TQ62@1239,3F3YQ@33958,4HAJ1@91061,COG1061@1,COG1061@2 NA|NA|NA L Helicase C-terminal domain protein LEHHPAIP_00775 349123.Lreu23DRAFT_4230 2.7e-77 294.7 Lactobacillaceae Bacteria 1VCFK@1239,2DNFZ@1,32XB4@2,3F7GM@33958,4IG23@91061 NA|NA|NA S Siphovirus Gp157 LEHHPAIP_00776 349123.Lreu23DRAFT_4232 1.2e-29 135.2 Lactobacillaceae Bacteria 1U8EP@1239,29G0D@1,302Y6@2,3FAWF@33958,4IICI@91061 NA|NA|NA LEHHPAIP_00778 349123.Lreu23DRAFT_4235 8.8e-40 169.5 Lactobacillaceae Bacteria 1U722@1239,29PUI@1,30ASP@2,3F8VP@33958,4IGWI@91061 NA|NA|NA LEHHPAIP_00780 365659.smi_0409 6e-15 87.0 Streptococcus mitis XK27_10050 Bacteria 1VDKY@1239,2TQ9P@28037,4IS6B@91061,COG1396@1,COG1396@2,COG2932@1,COG2932@2 NA|NA|NA K Peptidase S24-like LEHHPAIP_00781 1227360.C176_15972 2.4e-19 102.1 Planococcaceae Bacteria 1U5SG@1239,26HNZ@186818,4II4P@91061,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase LEHHPAIP_00782 349123.Lreu23DRAFT_4241 9.7e-69 266.2 Lactobacillaceae Bacteria 1U85Z@1239,2ATXK@1,3196B@2,3FAK8@33958,4II3H@91061 NA|NA|NA LEHHPAIP_00783 1300150.EMQU_2343 2.7e-26 125.9 Enterococcaceae Bacteria 1VGV0@1239,2DMUJ@1,32TRR@2,4B2B7@81852,4HKWA@91061 NA|NA|NA S Domain of unknown function (DUF4352) LEHHPAIP_00784 349123.Lreu23DRAFT_4243 8.6e-143 513.5 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_00794 557436.Lreu_1853 6.3e-238 830.1 Lactobacillaceae acm2 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 1UYRM@1239,3F4XJ@33958,4HAU6@91061,COG1388@1,COG1388@2,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase LEHHPAIP_00795 349123.Lreu23DRAFT_4750 3.5e-49 200.7 Lactobacillaceae czrA ko:K21903,ko:K22043 ko00000,ko03000 Bacteria 1VA6G@1239,3F7DH@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator, ArsR family LEHHPAIP_00796 557436.Lreu_1855 2.5e-36 157.5 Lactobacillaceae Bacteria 1U74X@1239,29PWM@1,30AUZ@2,3F8ZC@33958,4IGZK@91061 NA|NA|NA LEHHPAIP_00797 349123.Lreu23DRAFT_4753 0.0 1189.9 Lactobacillaceae yhcA ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1TPBJ@1239,3F44P@33958,4HBK7@91061,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein LEHHPAIP_00798 349123.Lreu23DRAFT_4754 1.3e-117 429.1 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1TQP5@1239,3F4RP@33958,4HBXK@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein LEHHPAIP_00799 557436.Lreu_1858 2.1e-167 595.1 Lactobacillaceae hrtB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TWFZ@1239,3F3K5@33958,4H9RQ@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease LEHHPAIP_00800 557436.Lreu_1859 1.8e-84 318.5 Lactobacillaceae ygfC Bacteria 1VXZV@1239,3FCEI@33958,4HXIZ@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator (TetR family) LEHHPAIP_00801 349123.Lreu23DRAFT_4757 9.9e-191 672.5 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3FC44@33958,4HVQZ@91061,COG1063@1,COG1063@2 NA|NA|NA E Alcohol dehydrogenase GroES-like domain LEHHPAIP_00802 557436.Lreu_1861 1.2e-286 991.9 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system LEHHPAIP_00803 1314.HKU360_01100 3.9e-237 827.0 Bacilli Bacteria 1V37H@1239,4HGN5@91061,COG3464@1,COG3464@2 NA|NA|NA L Transposase LEHHPAIP_00804 557436.Lreu_1538 6e-199 699.9 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1V5UK@1239,3FC7G@33958,4HTRY@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose LEHHPAIP_00805 349123.Lreu23DRAFT_4461 8.3e-21 105.5 Lactobacillaceae Bacteria 1U81E@1239,29QFZ@1,30BFD@2,3FAEU@33958,4IHYU@91061 NA|NA|NA LEHHPAIP_00806 557436.Lreu_1537 6e-263 912.9 Lactobacillaceae Bacteria 1UCBA@1239,3F3JA@33958,4HBCI@91061,COG4320@1,COG4320@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2252) LEHHPAIP_00807 334390.LAF_0133 1.4e-167 595.9 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family LEHHPAIP_00808 557436.Lreu_1536 1e-295 1021.9 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1UCSJ@1239,3FBNC@33958,4HMXT@91061,COG4974@1,COG4974@2 NA|NA|NA L PFAM plasmid pRiA4b ORF-3 family protein LEHHPAIP_00809 557436.Lreu_1535 3.3e-205 720.7 Lactobacillaceae adhA 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TP5B@1239,3F599@33958,4HVD8@91061,COG1064@1,COG1064@2 NA|NA|NA C Zinc-binding alcohol dehydrogenase family protein LEHHPAIP_00810 349123.Lreu23DRAFT_4457 6.6e-110 403.3 Lactobacillaceae ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,3F3TI@33958,4H9V0@91061,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides LEHHPAIP_00811 349123.Lreu23DRAFT_4456 4.3e-158 563.9 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family LEHHPAIP_00812 557436.Lreu_1532 1.2e-302 1045.0 Lactobacillaceae sfcA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0030145,GO:0036094,GO:0043167,GO:0043169,GO:0043464,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,3F3RH@33958,4HBF1@91061,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme LEHHPAIP_00813 557436.Lreu_1531 4e-259 900.2 Lactobacillaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHPH@1239,3F3K0@33958,4HA6P@91061,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate LEHHPAIP_00814 349123.Lreu23DRAFT_4453 5.8e-266 922.9 Lactobacillaceae frdC 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F3KJ@33958,4HAXN@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain LEHHPAIP_00815 349123.Lreu23DRAFT_4452 4.9e-252 876.7 Lactobacillaceae yflS ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3F4RH@33958,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region LEHHPAIP_00816 1314.HKU360_01100 3.9e-237 827.0 Bacilli Bacteria 1V37H@1239,4HGN5@91061,COG3464@1,COG3464@2 NA|NA|NA L Transposase LEHHPAIP_00817 349123.Lreu23DRAFT_4663 0.0 1227.6 Lactobacillaceae lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter LEHHPAIP_00818 349123.Lreu23DRAFT_4662 2.3e-28 131.0 Lactobacillaceae Bacteria 1U6DN@1239,29PBP@1,30A9X@2,3F7NV@33958,4IG5D@91061 NA|NA|NA LEHHPAIP_00819 349123.Lreu23DRAFT_4661 7.1e-275 952.6 Lactobacillaceae gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 1TP4I@1239,3F3S8@33958,4H9NC@91061,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH LEHHPAIP_00820 349123.Lreu23DRAFT_4660 3.2e-286 990.3 Lactobacillaceae zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 1TPYF@1239,3F48G@33958,4HA73@91061,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone LEHHPAIP_00821 557436.Lreu_1764 4.4e-190 670.6 Lactobacillaceae yeaN GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 1TP9R@1239,3F52B@33958,4H9YZ@91061,COG2807@1,COG2807@2 NA|NA|NA P Transporter, major facilitator family protein LEHHPAIP_00822 349123.Lreu23DRAFT_4657 2.7e-73 281.2 Lactobacillaceae ko:K04750 ko00000 Bacteria 1V6QS@1239,3F6RM@33958,4HK80@91061,COG2764@1,COG2764@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase LEHHPAIP_00823 349123.Lreu23DRAFT_4656 2.7e-82 311.2 Lactobacillaceae nrdI ko:K03647 ko00000 Bacteria 1VWJA@1239,3FBB8@33958,4HW5I@91061,COG1780@1,COG1780@2 NA|NA|NA F Belongs to the NrdI family LEHHPAIP_00824 349123.Lreu23DRAFT_4655 3.5e-236 823.9 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain LEHHPAIP_00825 349123.Lreu23DRAFT_4654 1.4e-153 548.9 Lactobacillaceae ypdB ko:K01990,ko:K21397 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1U5IJ@1239,3F61E@33958,4IF9C@91061,COG1131@1,COG1131@2 NA|NA|NA V (ABC) transporter LEHHPAIP_00826 557436.Lreu_1759 2.5e-89 334.7 Lactobacillaceae 1.14.14.47,1.6.5.3,1.6.99.3 ko:K00329,ko:K00356,ko:K00491,ko:K21572 ko00190,ko00220,ko00330,ko01100,ko01110,map00190,map00220,map00330,map01100,map01110 R11711,R11712,R11713,R11945 RC00061,RC00177,RC00330,RC01044 ko00000,ko00001,ko01000,ko02000 8.A.46.1,8.A.46.3 Bacteria 1U673@1239,3F78A@33958,4IFXN@91061,COG0702@1,COG0702@2 NA|NA|NA GM epimerase LEHHPAIP_00827 349123.Lreu23DRAFT_4652 1.1e-89 335.9 Lactobacillaceae M1-874 ko:K13638,ko:K13640 ko00000,ko03000 Bacteria 1V7Z4@1239,3FBF9@33958,4HJXK@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) LEHHPAIP_00828 349123.Lreu23DRAFT_4651 2.3e-78 298.1 Lactobacillaceae yybA 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1V3PS@1239,3F6VT@33958,4HFN6@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_00829 557436.Lreu_1756 5.7e-132 476.9 Lactobacillaceae XK27_07210 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TT38@1239,3F4C9@33958,4HCE2@91061,COG3382@1,COG3382@2 NA|NA|NA S B3 4 domain LEHHPAIP_00830 557436.Lreu_1755 2.6e-160 571.6 Lactobacillaceae Bacteria 1TQBF@1239,3F603@33958,4HGFS@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter LEHHPAIP_00831 349123.Lreu23DRAFT_4648 1.3e-156 558.9 Lactobacillaceae 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 1VSC9@1239,3F4RS@33958,4HUQI@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel LEHHPAIP_00832 557436.Lreu_1753 2.2e-160 571.6 Lactobacillaceae Bacteria 1U6HQ@1239,29PF5@1,30ADB@2,3F7XY@33958,4IGA0@91061 NA|NA|NA LEHHPAIP_00833 349123.Lreu23DRAFT_4646 1e-133 482.6 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family LEHHPAIP_00834 557436.Lreu_1751 3.6e-138 497.7 Lactobacillaceae eutJ ko:K04024 ko00000 Bacteria 1TQVV@1239,3F5YP@33958,4HGZA@91061,COG4820@1,COG4820@2 NA|NA|NA E Hsp70 protein LEHHPAIP_00835 557436.Lreu_1750 8.3e-159 566.6 Lactobacillaceae Bacteria 1V5UU@1239,3F728@33958,4IST3@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein LEHHPAIP_00836 557436.Lreu_1749 1.6e-37 161.8 Lactobacillaceae pduA_4 ko:K04027 ko00000 Bacteria 1VA0E@1239,3F7H9@33958,4HM6R@91061,COG4577@1,COG4577@2 NA|NA|NA CQ BMC LEHHPAIP_00837 557436.Lreu_1748 2.7e-134 484.6 Lactobacillaceae pduB Bacteria 1TTAA@1239,3F4UG@33958,4HTBP@91061,COG4816@1,COG4816@2 NA|NA|NA E BMC LEHHPAIP_00838 557436.Lreu_1747 0.0 1112.1 Lactobacillaceae pduC 4.2.1.28 ko:K01699 ko00640,map00640 R02376 RC00707 ko00000,ko00001,ko01000 iLF82_1304.LF82_332,iNRG857_1313.NRG857_10160,iYL1228.KPN_03205 Bacteria 1TPU7@1239,3F5RI@33958,4HDTR@91061,COG4909@1,COG4909@2 NA|NA|NA Q Dehydratase large subunit LEHHPAIP_00839 557436.Lreu_1746 3.9e-125 454.1 Lactobacillaceae pduD 4.2.1.28,4.2.1.30 ko:K06121,ko:K13919 ko00561,ko00640,map00561,map00640 R01047,R02376 RC00429,RC00707 ko00000,ko00001,ko01000 Bacteria 1UT3J@1239,3F5UH@33958,4HFWN@91061,COG4909@1,COG4909@2 NA|NA|NA Q Dehydratase medium subunit LEHHPAIP_00840 557436.Lreu_1745 6.2e-72 276.9 Lactobacillaceae pduE 4.2.1.28 ko:K13920 ko00640,map00640 R02376 RC00707 ko00000,ko00001,ko01000 Bacteria 1V5ZV@1239,3F6QG@33958,4HJW7@91061,COG4910@1,COG4910@2 NA|NA|NA Q Dehydratase small subunit LEHHPAIP_00841 557436.Lreu_1744 5.6e-309 1066.2 Lactobacillaceae pduG ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TQMU@1239,3F5AC@33958,4HC7H@91061,COG0849@1,COG0849@2 NA|NA|NA D Diol dehydratase reactivase ATPase-like domain LEHHPAIP_00842 557436.Lreu_1743 4.5e-45 187.2 Lactobacillaceae pduH Bacteria 1VC2J@1239,2EB43@1,3354T@2,3F804@33958,4HRRX@91061 NA|NA|NA S Dehydratase medium subunit LEHHPAIP_00843 557436.Lreu_1742 3.6e-57 228.0 Lactobacillaceae pduK Bacteria 1VEIA@1239,3F80D@33958,4HYCR@91061,COG4577@1,COG4577@2 NA|NA|NA CQ BMC LEHHPAIP_00844 557436.Lreu_1741 7.8e-40 169.5 Lactobacillaceae pduA_4 ko:K04027 ko00000 Bacteria 1VA0E@1239,3FBCP@33958,4HJNU@91061,COG4577@1,COG4577@2 NA|NA|NA CQ BMC LEHHPAIP_00845 557436.Lreu_1740 1.9e-115 421.8 Lactobacillaceae pduL 2.3.1.222,2.3.1.8 ko:K13923,ko:K15024 ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200 M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 Bacteria 1V242@1239,3FBCE@33958,4HI57@91061,COG4869@1,COG4869@2 NA|NA|NA Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate LEHHPAIP_00846 557436.Lreu_1739 1.3e-79 302.4 Lactobacillaceae Bacteria 1U6R6@1239,29PKK@1,30AIS@2,3F8CG@33958,4HWXH@91061 NA|NA|NA S Putative propanediol utilisation LEHHPAIP_00847 557436.Lreu_1738 5.2e-41 173.3 Lactobacillaceae ccmL ko:K04028 ko00000 Bacteria 1VEI4@1239,3F83B@33958,4HNX2@91061,COG4576@1,COG4576@2 NA|NA|NA CQ Ethanolamine utilisation protein EutN/carboxysome LEHHPAIP_00848 557436.Lreu_1737 2.2e-102 378.3 Lactobacillaceae pduO 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3PI@1239,3F6A2@33958,4IS1D@91061,COG2096@1,COG2096@2 NA|NA|NA S Cobalamin adenosyltransferase LEHHPAIP_00849 557436.Lreu_1736 4.5e-77 293.9 Lactobacillaceae pduO Bacteria 1V5C7@1239,3F6JA@33958,4HHN9@91061,COG3193@1,COG3193@2 NA|NA|NA S Haem-degrading LEHHPAIP_00850 557436.Lreu_1735 3.1e-262 910.6 Lactobacillaceae pduP 1.2.1.87 ko:K13922 ko00640,map00640 R09097 RC00004,RC00184 ko00000,ko00001,ko01000 Bacteria 1TRGK@1239,3F50C@33958,4HD2C@91061,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family LEHHPAIP_00851 557436.Lreu_1734 4.3e-203 713.8 Lactobacillaceae pduQ ko:K13921 ko00640,map00640 R02377 RC00087 ko00000,ko00001 Bacteria 1TPB4@1239,3F4V4@33958,4HD0X@91061,COG1454@1,COG1454@2 NA|NA|NA C Iron-containing alcohol dehydrogenase LEHHPAIP_00852 557436.Lreu_1733 3.8e-218 763.8 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1,2.7.2.15 ko:K00925,ko:K19697 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F5QY@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction LEHHPAIP_00853 557436.Lreu_1732 3e-54 217.6 Lactobacillaceae pduU ko:K04031 ko00000 Bacteria 1VB54@1239,3FBCN@33958,4HH8R@91061,COG4810@1,COG4810@2 NA|NA|NA E BMC LEHHPAIP_00854 557436.Lreu_1731 4.4e-117 427.6 Lactobacillaceae 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1VA24@1239,3F6NY@33958,4HMSH@91061,COG2365@1,COG2365@2 NA|NA|NA T Pfam:Y_phosphatase3C LEHHPAIP_00855 557436.Lreu_1730 3.3e-75 288.1 Lactobacillaceae pgm1 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6ES@1239,3F5SD@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase LEHHPAIP_00856 557436.Lreu_1729 5.9e-68 263.8 Bacteria Bacteria COG4300@1,COG4300@2 NA|NA|NA P Cadmium resistance transporter LEHHPAIP_00857 557436.Lreu_1728 2.6e-68 264.6 Lactobacillaceae eutP ko:K04029 ko00000 Bacteria 1VAYC@1239,3F7NM@33958,4HJN3@91061,COG4917@1,COG4917@2 NA|NA|NA E Ethanolamine utilisation - propanediol utilisation LEHHPAIP_00858 557436.Lreu_1727 2.9e-73 281.2 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1V7AG@1239,3F6HY@33958,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin LEHHPAIP_00859 557436.Lreu_1726 7.9e-117 426.8 Lactobacillaceae XK27_04590 ko:K19784 ko00000 Bacteria 1V282@1239,3F4MA@33958,4HHF5@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase LEHHPAIP_00860 557436.Lreu_1725 3.2e-77 294.7 Lactobacillaceae cobO 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3PI@1239,3FB6Q@33958,4HH26@91061,COG2096@1,COG2096@2 NA|NA|NA S Cobalamin adenosyltransferase LEHHPAIP_00861 557436.Lreu_1723 1.8e-169 602.1 Lactobacillaceae cobD 4.1.1.81 ko:K04720 ko00860,map00860 R06530 RC00517 ko00000,ko00001,ko01000 Bacteria 1TP5D@1239,3FB7J@33958,4HD85@91061,COG0079@1,COG0079@2 NA|NA|NA E Aminotransferase class I and II LEHHPAIP_00862 557436.Lreu_1722 8.1e-204 716.5 Lactobacillaceae cbiA 6.3.5.11,6.3.5.9 ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 R05224,R05815 RC00010,RC01301 ko00000,ko00001,ko01000 Bacteria 1TNY2@1239,3F3UC@33958,4H9SN@91061,COG1797@1,COG1797@2 NA|NA|NA F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source LEHHPAIP_00863 557436.Lreu_1721 4.9e-147 527.3 Lactobacillaceae cobD 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3X@1239,3F4J9@33958,4HA48@91061,COG1270@1,COG1270@2 NA|NA|NA H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group LEHHPAIP_00864 557436.Lreu_1720 2.5e-108 398.3 Lactobacillaceae cbiC 5.4.99.60,5.4.99.61 ko:K06042 ko00860,ko01100,map00860,map01100 R05177,R05814 RC01292,RC01980 ko00000,ko00001,ko01000 Bacteria 1V1SX@1239,3F659@33958,4HCSR@91061,COG2082@1,COG2082@2 NA|NA|NA H Precorrin-8X methylmutase LEHHPAIP_00865 557436.Lreu_1719 6.4e-186 656.8 Lactobacillaceae cbiD 2.1.1.195 ko:K02006,ko:K02188 ko00860,ko01100,ko02010,map00860,map01100,map02010 M00245,M00246 R07773 RC00003,RC02051 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1TQ3M@1239,3F638@33958,4HBDG@91061,COG1903@1,COG1903@2 NA|NA|NA H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A LEHHPAIP_00866 557436.Lreu_1718 1.6e-79 302.4 Lactobacillaceae cbiE 2.1.1.132,2.1.1.289 ko:K00595,ko:K03399 ko00860,ko01100,map00860,map01100 R05149,R05813,R07775 RC00003,RC01279,RC02052,RC02053 ko00000,ko00001,ko01000 iHN637.CLJU_RS15725 Bacteria 1V832@1239,3F6B8@33958,4HI86@91061,COG2241@1,COG2241@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases LEHHPAIP_00867 557436.Lreu_1717 1.4e-77 295.8 Lactobacillaceae cbiT 2.1.1.132,2.1.1.196 ko:K00595,ko:K02191 ko00860,ko01100,map00860,map01100 R05149,R05813,R07774 RC00003,RC01279,RC02052,RC02054 ko00000,ko00001,ko01000 Bacteria 1TS3H@1239,3F6ID@33958,4HAP3@91061,COG2242@1,COG2242@2 NA|NA|NA H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LEHHPAIP_00868 557436.Lreu_1716 8.1e-129 466.5 Lactobacillaceae cobM 1.3.1.76,2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,4.99.1.4 ko:K02304,ko:K05936,ko:K13541 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947,R05180,R05181,R05809,R05810,R07772 RC00003,RC01012,RC01034,RC01293,RC01294,RC01545,RC02049,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6J@1239,3F5NQ@33958,4HBN5@91061,COG2875@1,COG2875@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases LEHHPAIP_00869 557436.Lreu_1715 3.3e-144 518.1 Lactobacillaceae cbiG 2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12 ko:K02189,ko:K05934,ko:K05936,ko:K13541 ko00860,ko01100,map00860,map01100 R05180,R05181,R05809,R05810,R07772 RC00003,RC01293,RC01294,RC01545,RC02049,RC02097,RC03471 ko00000,ko00001,ko01000 iHN637.CLJU_RS15705 Bacteria 1TPYM@1239,3F5AW@33958,4HAX7@91061,COG2073@1,COG2073@2 NA|NA|NA H Cobalamin synthesis G C-terminus LEHHPAIP_00870 557436.Lreu_1714 1.1e-127 462.6 Lactobacillaceae cobJ 2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,6.3.5.10 ko:K02232,ko:K05934,ko:K05936,ko:K13541 ko00860,ko01100,map00860,map01100 M00122 R05180,R05181,R05225,R05809,R05810,R07772 RC00003,RC00010,RC01293,RC01294,RC01302,RC01545,RC02049,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPJ7@1239,3F5GP@33958,4HCQ1@91061,COG1010@1,COG1010@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases LEHHPAIP_00871 557436.Lreu_1713 2.5e-98 365.2 Lactobacillaceae cobK 1.3.1.106,1.3.1.54,2.1.1.195 ko:K02188,ko:K05895 ko00860,ko01100,map00860,map01100 R05150,R05812,R07773 RC00003,RC01280,RC02051 ko00000,ko00001,ko01000 iHN637.CLJU_RS15690 Bacteria 1UHWY@1239,3F5CX@33958,4HC6V@91061,COG2099@1,COG2099@2 NA|NA|NA H Precorrin-6x reductase CbiJ/CobK LEHHPAIP_00872 557436.Lreu_1712 2.7e-178 631.7 Lactobacillaceae cobA 2.1.1.107,4.2.1.75 ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQNH@1239,3F5SP@33958,4HBB7@91061,COG0007@1,COG0007@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases LEHHPAIP_00873 557436.Lreu_1711 1.1e-107 396.4 Lactobacillaceae cbiK GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016829,GO:0016852,GO:0017144,GO:0018130,GO:0019251,GO:0019438,GO:0020037,GO:0022607,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0042597,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050897,GO:0051186,GO:0051188,GO:0051259,GO:0051262,GO:0051266,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.99.1.3 ko:K02190 ko00860,ko01100,map00860,map01100 R05807 RC01012 ko00000,ko00001,ko01000 Bacteria 1TQ5V@1239,3F6A6@33958,4HGQK@91061,COG4822@1,COG4822@2 NA|NA|NA H Cobalt chelatase (CbiK) LEHHPAIP_00874 557436.Lreu_1710 8.1e-91 340.1 Lactobacillaceae cobI 2.1.1.130,2.1.1.151,4.99.1.3 ko:K02190,ko:K03394 ko00860,ko01100,map00860,map01100 R03948,R05807,R05808 RC00003,RC01012,RC01035,RC01662 ko00000,ko00001,ko01000 Bacteria 1TP87@1239,3F67P@33958,4HB4V@91061,COG2243@1,COG2243@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases LEHHPAIP_00875 557436.Lreu_1709 8.5e-123 446.4 Lactobacillaceae cbiM GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02007 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1TQVK@1239,3FBNJ@33958,4HBKM@91061,COG0310@1,COG0310@2 NA|NA|NA P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import LEHHPAIP_00876 557436.Lreu_1708 7.6e-44 183.0 Lactobacillaceae cbiN GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02009 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18 Bacteria 1VF03@1239,3F7KG@33958,4HNIU@91061,COG1930@1,COG1930@2 NA|NA|NA P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import LEHHPAIP_00877 557436.Lreu_1707 6.8e-103 380.2 Lactobacillaceae cbiQ ko:K02008 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1V0B0@1239,3F690@33958,4HKD3@91061,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein LEHHPAIP_00878 557436.Lreu_1706 7.8e-122 443.4 Lactobacillaceae cbiO GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 2.1.1.195 ko:K02006,ko:K02188 ko00860,ko01100,ko02010,map00860,map01100,map02010 M00245,M00246 R07773 RC00003,RC02051 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1TPH8@1239,3F559@33958,4HAHF@91061,COG1122@1,COG1122@2 NA|NA|NA P part of an ABC transporter complex. Responsible for energy coupling to the transport system LEHHPAIP_00879 557436.Lreu_1705 6.6e-239 833.2 Lactobacillaceae cobQ 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS15780,iJN678.cbiP Bacteria 1TP5E@1239,3F55X@33958,4HAQW@91061,COG1492@1,COG1492@2 NA|NA|NA H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation LEHHPAIP_00880 557436.Lreu_1704 2.7e-58 231.5 Lactobacillaceae cysG 1.3.1.76,4.99.1.4 ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947 RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA2E@1239,3F7WD@33958,4HIRG@91061,COG1648@1,COG1648@2 NA|NA|NA H Putative NAD(P)-binding LEHHPAIP_00881 557436.Lreu_1703 5.4e-194 683.7 Lactobacillaceae hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009288,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0042597,GO:0042802,GO:0042995,GO:0043226,GO:0043228,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055040,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02407,ko:K02492,ko:K10714,ko:K15671 ko00680,ko00860,ko01051,ko01052,ko01100,ko01110,ko01120,ko01200,ko02040,map00680,map00860,map01051,map01052,map01100,map01110,map01120,map01200,map02040 M00121 R04109,R08059 RC00055,RC00149,RC00202 ko00000,ko00001,ko00002,ko01000,ko01008,ko02035 iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iSB619.SA_RS08420,iUTI89_1310.UTI89_C1404 Bacteria 1TQN9@1239,3F5CK@33958,4HAVC@91061,COG0373@1,COG0373@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) LEHHPAIP_00882 557436.Lreu_1702 9.8e-137 493.0 Lactobacillaceae hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01749,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iHN637.CLJU_RS15760,iPC815.YPO3849 Bacteria 1TPFQ@1239,3F5UC@33958,4H9TV@91061,COG0181@1,COG0181@2 NA|NA|NA H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps LEHHPAIP_00883 557436.Lreu_1701 6.2e-174 616.7 Lactobacillaceae hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TP09@1239,3F5DY@33958,4HBQC@91061,COG0113@1,COG0113@2 NA|NA|NA H Delta-aminolevulinic acid dehydratase LEHHPAIP_00884 557436.Lreu_1700 4.3e-239 833.6 Lactobacillaceae hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 iUMNK88_1353.UMNK88_158 Bacteria 1TPNH@1239,3FBCC@33958,4HANQ@91061,COG0001@1,COG0001@2 NA|NA|NA H Aminotransferase class-III LEHHPAIP_00885 557436.Lreu_1699 1.6e-76 292.4 Lactobacillaceae cobU GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568 2.7.1.156,2.7.7.62,6.3.5.10 ko:K02231,ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05221,R05222,R05225,R06558 RC00002,RC00010,RC00428,RC01302 ko00000,ko00001,ko00002,ko01000 iECIAI1_1343.ECIAI1_2074,iECSE_1348.ECSE_2277,iECW_1372.ECW_m2165,iETEC_1333.ETEC_2103,iEcE24377_1341.EcE24377A_2275,iEcSMS35_1347.EcSMS35_1131,iEcolC_1368.EcolC_1635,iLF82_1304.LF82_0337,iSDY_1059.SDY_2240,iWFL_1372.ECW_m2165 Bacteria 1V6F8@1239,3F71H@33958,4HKIE@91061,COG2087@1,COG2087@2 NA|NA|NA H Cobinamide kinase / cobinamide phosphate guanyltransferase LEHHPAIP_00886 557436.Lreu_1698 2.2e-118 431.8 Lactobacillaceae cobS GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 ko:K02233 ko00860,ko01100,map00860,map01100 M00122 R05223,R11174 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_2837,iECO103_1326.ECO103_2453,iECSP_1301.ECSP_2657,iECs_1301.ECs2787,iG2583_1286.G2583_2502,iUTI89_1310.UTI89_C2230,iZ_1308.Z3152,ic_1306.c2478 Bacteria 1V1QB@1239,3F5PT@33958,4HM4K@91061,COG0368@1,COG0368@2 NA|NA|NA H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate LEHHPAIP_00887 557436.Lreu_1697 5.8e-74 283.9 Lactobacillaceae gpm 3.1.3.73,5.4.2.12 ko:K02226,ko:K15634 ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00122 R01518,R04594,R11173 RC00017,RC00536 ko00000,ko00001,ko00002,ko01000 Bacteria 1VEMM@1239,3F7IC@33958,4HPA5@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family LEHHPAIP_00888 557436.Lreu_1696 6.5e-64 250.8 Lactobacillaceae hemD 2.1.1.107,4.2.1.75 ko:K01719,ko:K13542,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 1U6TZ@1239,3F8HG@33958,4IGMT@91061,COG1587@1,COG1587@2 NA|NA|NA H Uroporphyrinogen-III synthase LEHHPAIP_00889 557436.Lreu_1695 1.6e-146 525.8 Lactobacillaceae cobT GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21,6.3.5.11,6.3.5.9 ko:K00768,ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 M00122 R04148,R05224,R05815 RC00010,RC00033,RC00063,RC01301 ko00000,ko00001,ko00002,ko01000 iSDY_1059.SDY_2242,iSF_1195.SF2059,iSFxv_1172.SFxv_2293,iS_1188.S2169 Bacteria 1TPC1@1239,3F5K0@33958,4HAE0@91061,COG2038@1,COG2038@2 NA|NA|NA F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) LEHHPAIP_00890 1120998.AUFC01000012_gene467 1.8e-55 223.0 Clostridia cnrT Bacteria 1TPST@1239,248K5@186801,COG0697@1,COG0697@2 NA|NA|NA EG PFAM EamA-like transporter family LEHHPAIP_00891 557436.Lreu_1694 1.7e-50 205.3 Lactobacillaceae Bacteria 1VF26@1239,2DNM7@1,32Y2X@2,3F6AM@33958,4HP82@91061 NA|NA|NA S Domain of unknown function (DUF4430) LEHHPAIP_00892 557436.Lreu_1693 1.1e-71 276.2 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V5GD@1239,3F5H7@33958,4HI8Y@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF transporter, substrate-specific component LEHHPAIP_00893 525309.HMPREF0494_2191 2.9e-19 100.5 Lactobacillaceae Bacteria 1V0EH@1239,3F4KW@33958,4HXBI@91061,COG1672@1,COG1672@2 NA|NA|NA S PFAM Archaeal ATPase LEHHPAIP_00894 349123.Lreu23DRAFT_4645 5.5e-179 633.6 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3FB6C@33958,4HH0S@91061,COG1052@1,COG1052@2 NA|NA|NA C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family LEHHPAIP_00895 908339.HMPREF9265_1369 1.3e-17 96.3 Lactobacillaceae Bacteria 1TTKV@1239,3F7IS@33958,4IG35@91061,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain LEHHPAIP_00896 349123.Lreu23DRAFT_4643 1.8e-288 998.0 Lactobacillaceae lmrA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein LEHHPAIP_00897 349123.Lreu23DRAFT_4642 0.0 1093.2 Lactobacillaceae yfiC ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter LEHHPAIP_00898 324831.LGAS_1503 0.0 1120.1 Lactobacillaceae rtpR 1.1.98.6,1.17.4.1,1.17.4.2 ko:K00525,ko:K00527,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02017,R02018,R02019,R02020,R02022,R02023,R02024,R04315,R11633,R11634,R11635,R11636 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TT3U@1239,3F3VU@33958,4HFF1@91061,COG0209@1,COG0209@2 NA|NA|NA F ribonucleoside-triphosphate reductase activity LEHHPAIP_00899 349123.Lreu23DRAFT_4641 2.6e-269 934.1 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase LEHHPAIP_00900 349123.Lreu23DRAFT_4640 1.6e-85 322.0 Lactobacillaceae ybaK ko:K03976 ko00000,ko01000,ko03016 Bacteria 1V6JF@1239,3FC62@33958,4HHFK@91061,COG2606@1,COG2606@2 NA|NA|NA J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily LEHHPAIP_00901 349123.Lreu23DRAFT_4638 4.7e-126 457.2 Lactobacillaceae gntR ko:K03710 ko00000,ko03000 Bacteria 1TTCD@1239,3F4DA@33958,4HEXQ@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein LEHHPAIP_00902 1423814.HMPREF0549_1190 0.0 1647.1 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase LEHHPAIP_00903 349123.Lreu23DRAFT_4636 2.4e-17 94.0 Lactobacillaceae yagE Bacteria 1VTJD@1239,3FCAN@33958,4HTQM@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00904 557436.Lreu_1685 2.1e-116 425.2 Lactobacillaceae yagE Bacteria 1VTJD@1239,3FCAN@33958,4HTQM@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00905 349123.Lreu23DRAFT_4636 4.6e-80 303.9 Lactobacillaceae yagE Bacteria 1VTJD@1239,3FCAN@33958,4HTQM@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_00906 557436.Lreu_1684 4.2e-138 497.3 Lactobacillaceae aroD ko:K06889 ko00000 Bacteria 1UXYN@1239,3FB9J@33958,4HA7V@91061,COG1073@1,COG1073@2 NA|NA|NA S Serine hydrolase (FSH1) LEHHPAIP_00907 557436.Lreu_1681 9.1e-240 835.9 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids LEHHPAIP_00908 557436.Lreu_1680 8.4e-165 586.3 Lactobacillaceae Bacteria 1V3T9@1239,3FC7F@33958,4HU07@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family LEHHPAIP_00909 557436.Lreu_1679 0.0 1243.0 Lactobacillaceae tetP ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPQH@1239,3F4B4@33958,4HAS9@91061,COG0480@1,COG0480@2 NA|NA|NA J elongation factor G LEHHPAIP_00910 349123.Lreu23DRAFT_4631 2.5e-80 304.7 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein LEHHPAIP_00911 557436.Lreu_1677 5.1e-195 686.8 Lactobacillaceae lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F4UZ@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase LEHHPAIP_00912 557436.Lreu_1676 7.1e-63 246.5 Lactobacillaceae Bacteria 1U68K@1239,29P7S@1,30A5V@2,3F7B2@33958,4IFZG@91061 NA|NA|NA LEHHPAIP_00913 797515.HMPREF9103_01494 8.9e-14 83.6 Lactobacillaceae Bacteria 1UFZH@1239,29V33@1,30GGE@2,3F5BQ@33958,4IF1H@91061 NA|NA|NA LEHHPAIP_00914 1314.HKU360_01100 3.9e-237 827.0 Bacilli Bacteria 1V37H@1239,4HGN5@91061,COG3464@1,COG3464@2 NA|NA|NA L Transposase LEHHPAIP_00915 557436.Lreu_0151 2.8e-188 664.5 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family LEHHPAIP_00916 557436.Lreu_0478 1.5e-147 528.9 Lactobacillaceae 2.3.1.19 ko:K00634,ko:K07729 ko00650,ko01100,map00650,map01100 R01174 RC00004,RC02816 ko00000,ko00001,ko01000,ko03000 Bacteria 1VMYH@1239,3F5QH@33958,4ISF0@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins LEHHPAIP_00917 557436.Lreu_0477 3.4e-216 757.3 Lactobacillaceae ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP2Y@1239,3F41Z@33958,4H9KB@91061,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family LEHHPAIP_00918 349123.Lreu23DRAFT_3533 1.4e-47 195.3 Lactobacillaceae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1V6WV@1239,3F7WB@33958,4HIMA@91061,COG0509@1,COG0509@2 NA|NA|NA E glycine cleavage LEHHPAIP_00919 349123.Lreu23DRAFT_3532 1.1e-220 772.3 Lactobacillaceae rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,3F4J4@33958,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family LEHHPAIP_00920 349123.Lreu23DRAFT_3531 1e-31 142.1 Lactobacillaceae Bacteria 1U6D6@1239,2BRKM@1,32KJX@2,3F7N5@33958,4IG4Y@91061 NA|NA|NA S Protein of unknown function (DUF2969) LEHHPAIP_00921 349123.Lreu23DRAFT_3530 1.9e-178 631.7 Lactobacillaceae mbl ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F463@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D Cell shape determining protein MreB Mrl LEHHPAIP_00922 349123.Lreu23DRAFT_3529 3e-240 837.4 Lactobacillaceae murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine LEHHPAIP_00923 557436.Lreu_0469 1.3e-33 148.7 Lactobacillaceae ywzB Bacteria 1VK5C@1239,3F88D@33958,4HR8D@91061,COG4836@1,COG4836@2 NA|NA|NA S Protein of unknown function (DUF1146) LEHHPAIP_00924 349123.Lreu23DRAFT_3528 3.8e-67 260.8 Lactobacillaceae atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1VA89@1239,3F6I6@33958,4HKHS@91061,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane LEHHPAIP_00925 349123.Lreu23DRAFT_3527 1.1e-267 928.7 Lactobacillaceae atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10965 Bacteria 1TPGF@1239,3F3TF@33958,4HAT6@91061,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits LEHHPAIP_00926 349123.Lreu23DRAFT_3526 4.8e-163 580.5 Lactobacillaceae atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820 Bacteria 1TPBX@1239,3F40E@33958,4HB0E@91061,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex LEHHPAIP_00927 349123.Lreu23DRAFT_3525 4.4e-283 979.9 Lactobacillaceae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1TNZ8@1239,3F3R4@33958,4HAMZ@91061,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit LEHHPAIP_00928 349123.Lreu23DRAFT_3524 5.1e-93 347.1 Lactobacillaceae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VAG3@1239,3FC80@33958,4HKFW@91061,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation LEHHPAIP_00929 349123.Lreu23DRAFT_3523 1.1e-57 229.6 Lactobacillaceae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01170,iYO844.BSU36850 Bacteria 1VB85@1239,3F5M8@33958,4HM64@91061,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) LEHHPAIP_00930 1423814.HMPREF0549_0811 1.5e-14 85.1 Lactobacillaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VEHP@1239,3F82A@33958,4HNKQ@91061,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation LEHHPAIP_00931 349123.Lreu23DRAFT_3521 7.3e-124 449.9 Lactobacillaceae atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1TQIT@1239,3F3RE@33958,4H9NV@91061,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane LEHHPAIP_00932 349123.Lreu23DRAFT_3520 7.7e-233 812.8 Lactobacillaceae pyrP ko:K02824 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 iLJ478.TM0819 Bacteria 1TQKX@1239,3F3UJ@33958,4HAEU@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease LEHHPAIP_00933 349123.Lreu23DRAFT_3519 4.4e-130 470.7 Lactobacillaceae yibF Bacteria 1TSWX@1239,3F3S6@33958,4HBKX@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name LEHHPAIP_00934 557436.Lreu_0458 2.9e-191 674.5 Lactobacillaceae yibE Bacteria 1TPEV@1239,3F3M9@33958,4HCP3@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name LEHHPAIP_00935 557436.Lreu_0457 0.0 1105.1 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) LEHHPAIP_00936 557436.Lreu_0456 6.6e-116 423.3 Lactobacillaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,3F4M0@33958,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate LEHHPAIP_00937 349123.Lreu23DRAFT_3515 2.3e-229 801.2 Lactobacillaceae glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVM@1239,3F4C1@33958,4HA5K@91061,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism LEHHPAIP_00938 557436.Lreu_0454 1.4e-195 688.7 Lactobacillaceae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP1I@1239,3F3T1@33958,4HA7W@91061,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine LEHHPAIP_00939 557436.Lreu_0453 1.5e-166 592.0 Lactobacillaceae prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1TSMA@1239,3F460@33958,4HC6W@91061,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif LEHHPAIP_00940 557436.Lreu_0452 1.2e-194 685.6 Lactobacillaceae prfA ko:K02835 ko00000,ko03012 Bacteria 1TQ7V@1239,3F3Q0@33958,4H9MB@91061,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA LEHHPAIP_00941 557436.Lreu_0451 1.7e-107 395.2 Lactobacillaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 1TRVM@1239,3F4UE@33958,4HA4A@91061,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase LEHHPAIP_00942 557436.Lreu_0450 2.2e-262 911.0 Lactobacillaceae murD 3.4.21.10,6.3.2.13,6.3.2.9 ko:K01317,ko:K01925,ko:K01928,ko:K01932 ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100 R02783,R02788 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011,ko04131 Bacteria 1UHPI@1239,3F3TN@33958,4HVP0@91061,COG0771@1,COG0771@2 NA|NA|NA M Mur ligase, middle domain LEHHPAIP_00943 557436.Lreu_0449 1.2e-134 485.7 Lactobacillaceae cobQ ko:K07009 ko00000 Bacteria 1UYMA@1239,3FBI0@33958,4HEXH@91061,COG3442@1,COG3442@2 NA|NA|NA S CobB/CobQ-like glutamine amidotransferase domain LEHHPAIP_00944 908339.HMPREF9265_1799 3e-10 71.2 Lactobacillaceae Bacteria 1U6GY@1239,29PEK@1,30ACS@2,3F7WA@33958,4IG95@91061 NA|NA|NA LEHHPAIP_00945 557436.Lreu_0448 6.1e-223 780.0 Lactobacillaceae arcD ko:K03758 ko00000,ko02000 2.A.3.2 Bacteria 1TSSB@1239,3F84A@33958,4HA92@91061,COG0531@1,COG0531@2 NA|NA|NA U Amino acid permease LEHHPAIP_00946 349123.Lreu23DRAFT_3507 1.1e-259 902.1 Lactobacillaceae ko:K03758 ko00000,ko02000 2.A.3.2 Bacteria 1TSSB@1239,3F3P5@33958,4HA92@91061,COG0531@1,COG0531@2 NA|NA|NA E Arginine ornithine antiporter LEHHPAIP_00947 349123.Lreu23DRAFT_3506 2.7e-79 301.2 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1VA3U@1239,3F65K@33958,4HPCQ@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes LEHHPAIP_00948 557436.Lreu_0445 2e-217 761.5 Lactobacillaceae arcA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 1TQWS@1239,3F4VJ@33958,4HCMG@91061,COG2235@1,COG2235@2 NA|NA|NA E Arginine LEHHPAIP_00949 557436.Lreu_0444 1.5e-183 648.7 Lactobacillaceae ampC Bacteria 1U828@1239,3FBDZ@33958,4HA0Q@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase LEHHPAIP_00950 557436.Lreu_0443 7e-19 100.9 Lactobacillaceae Bacteria 1VQCC@1239,2DI2W@1,33GVK@2,3F8BF@33958,4HR7Z@91061 NA|NA|NA LEHHPAIP_00951 349123.Lreu23DRAFT_3502 0.0 1302.7 Bacteria Bacteria COG4932@1,COG4932@2 NA|NA|NA M domain protein LEHHPAIP_00952 349123.Lreu23DRAFT_3502 9.7e-139 499.6 Bacteria Bacteria COG4932@1,COG4932@2 NA|NA|NA M domain protein LEHHPAIP_00953 349123.Lreu23DRAFT_3501 3.8e-90 338.2 Lactobacillaceae Bacteria 1U6AG@1239,29P9C@1,30A7G@2,3F7FY@33958,4IG1U@91061 NA|NA|NA LEHHPAIP_00954 575594.ACOH01000010_gene1683 7e-134 483.8 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_00955 1423724.BAMM01000034_gene2134 2e-08 66.6 Bacteria xre Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding LEHHPAIP_00956 908339.HMPREF9265_0357 2.6e-12 77.8 Lactobacillaceae Bacteria 1U748@1239,29PW2@1,30AUC@2,3F8Y9@33958,4IGYU@91061 NA|NA|NA LEHHPAIP_00957 575594.ACOH01000010_gene1679 1.5e-29 135.6 Lactobacillaceae Bacteria 1U8F0@1239,29QPT@1,30BPH@2,3FAWV@33958,4IICW@91061 NA|NA|NA LEHHPAIP_00958 663952.SDD27957_00585 1.8e-39 169.5 Bacilli ko:K14623 ko00000,ko03400 Bacteria 1VUFB@1239,4HVHU@91061,COG3617@1,COG3617@2 NA|NA|NA K COG3617 Prophage antirepressor LEHHPAIP_00960 1423724.BAMM01000034_gene2128 5e-08 63.9 Lactobacillaceae Bacteria 1U71P@1239,2DKTQ@1,30ASD@2,3F8V7@33958,4IGW6@91061 NA|NA|NA LEHHPAIP_00964 632245.CLP_3324 8.9e-09 68.2 Clostridiaceae Bacteria 1TQT6@1239,24I78@186801,36JE7@31979,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein LEHHPAIP_00966 557436.Lreu_0438 5.5e-68 263.5 Bacilli Bacteria 1W5ZE@1239,2BZQS@1,2ZTX2@2,4HZHP@91061 NA|NA|NA LEHHPAIP_00969 557436.Lreu_0437 4.6e-53 213.8 Lactobacillaceae Bacteria 1U7TI@1239,29QBA@1,30BAH@2,3FA5N@33958,4IHR0@91061 NA|NA|NA LEHHPAIP_00972 349123.Lreu23DRAFT_3500 1.4e-47 195.3 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter LEHHPAIP_00973 349123.Lreu23DRAFT_3500 5.9e-117 427.2 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter LEHHPAIP_00974 349123.Lreu23DRAFT_3500 3.9e-40 171.0 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter LEHHPAIP_00975 349123.Lreu23DRAFT_3499 2.3e-56 224.6 Lactobacillaceae Bacteria 1W08C@1239,2FI40@1,349WT@2,3F7QX@33958,4HYGC@91061 NA|NA|NA LEHHPAIP_00977 557436.Lreu_0432 1.2e-85 322.4 Lactobacillaceae Bacteria 1U62W@1239,29P3K@1,30A1T@2,3F6X0@33958,4IFS1@91061 NA|NA|NA LEHHPAIP_00978 557436.Lreu_0431 0.0 1182.9 Lactobacillaceae copA 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase LEHHPAIP_00979 349123.Lreu23DRAFT_3495 1.1e-49 202.6 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1TQ02@1239,3FBQA@33958,4IRVT@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain LEHHPAIP_00980 557436.Lreu_0428 1.4e-101 375.6 Lactobacillaceae XK27_08875 Bacteria 1VW9X@1239,3F60X@33958,4HWF8@91061,COG5549@1,COG5549@2 NA|NA|NA O PFAM peptidase M10A and M12B, matrixin and adamalysin LEHHPAIP_00982 1329250.WOSG25_020250 1e-11 78.6 Bacilli Bacteria 1VK4J@1239,2EK2P@1,33DT4@2,4I15W@91061 NA|NA|NA S by MetaGeneAnnotator LEHHPAIP_00986 575594.ACOH01000003_gene776 5.2e-41 175.3 Lactobacillaceae Bacteria 1UV2A@1239,29WTK@1,30IEZ@2,3F6DE@33958,4I41W@91061 NA|NA|NA S Domain of unknown function (DUF2479) LEHHPAIP_00989 908339.HMPREF9265_0933 6e-218 764.2 Bacilli ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VW67@1239,4HWSY@91061,COG0791@1,COG0791@2 NA|NA|NA M CHAP domain LEHHPAIP_00990 349123.Lreu23DRAFT_3984 1.9e-81 309.3 Lactobacillaceae Bacteria 1VGQF@1239,2E9AZ@1,333IU@2,3F5IA@33958,4HQBT@91061 NA|NA|NA S Phage tail protein LEHHPAIP_00991 908339.HMPREF9265_0935 5.2e-131 475.7 Lactobacillaceae Z012_10445 Bacteria 1TQ28@1239,3F5K4@33958,4HAFE@91061,COG5283@1,COG5283@2,COG5412@1,COG5412@2 NA|NA|NA D Phage tail tape measure protein LEHHPAIP_00992 908339.HMPREF9265_0936 8.2e-14 83.2 Lactobacillaceae Bacteria 1VKIN@1239,2EHS8@1,33BHZ@2,3F7N3@33958,4HR6E@91061 NA|NA|NA LEHHPAIP_00994 1329250.WOSG25_020250 1e-11 78.6 Bacilli Bacteria 1VK4J@1239,2EK2P@1,33DT4@2,4I15W@91061 NA|NA|NA S by MetaGeneAnnotator LEHHPAIP_00998 575594.ACOH01000003_gene776 5.2e-41 175.3 Lactobacillaceae Bacteria 1UV2A@1239,29WTK@1,30IEZ@2,3F6DE@33958,4I41W@91061 NA|NA|NA S Domain of unknown function (DUF2479) LEHHPAIP_01001 908339.HMPREF9265_0933 1.5e-224 786.2 Bacilli ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VW67@1239,4HWSY@91061,COG0791@1,COG0791@2 NA|NA|NA M CHAP domain LEHHPAIP_01002 349123.Lreu23DRAFT_3984 1.4e-90 339.7 Lactobacillaceae Bacteria 1VGQF@1239,2E9AZ@1,333IU@2,3F5IA@33958,4HQBT@91061 NA|NA|NA S Phage tail protein LEHHPAIP_01003 908339.HMPREF9265_0935 1.8e-134 487.3 Lactobacillaceae Z012_10445 Bacteria 1TQ28@1239,3F5K4@33958,4HAFE@91061,COG5283@1,COG5283@2,COG5412@1,COG5412@2 NA|NA|NA D Phage tail tape measure protein LEHHPAIP_01004 908339.HMPREF9265_0936 1.1e-13 82.8 Lactobacillaceae Bacteria 1VKIN@1239,2EHS8@1,33BHZ@2,3F7N3@33958,4HR6E@91061 NA|NA|NA LEHHPAIP_01005 349123.Lreu23DRAFT_3983 9.9e-21 106.7 Bacilli ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VW67@1239,4HWSY@91061,COG0791@1,COG0791@2,COG3953@1,COG3953@2 NA|NA|NA M CHAP domain LEHHPAIP_01008 575594.ACOH01000003_gene776 5.2e-41 175.3 Lactobacillaceae Bacteria 1UV2A@1239,29WTK@1,30IEZ@2,3F6DE@33958,4I41W@91061 NA|NA|NA S Domain of unknown function (DUF2479) LEHHPAIP_01012 1329250.WOSG25_020250 1e-11 78.6 Bacilli Bacteria 1VK4J@1239,2EK2P@1,33DT4@2,4I15W@91061 NA|NA|NA S by MetaGeneAnnotator LEHHPAIP_01014 1567453.A0A0A1ENR5_9CAUD 1.3e-31 142.5 Siphoviridae Viruses 4QFX5@10239,4QMC7@10699,4QRBG@28883 NA|NA|NA LEHHPAIP_01015 525309.HMPREF0494_1756 2.2e-24 118.6 Lactobacillaceae Bacteria 1U6IX@1239,29PG3@1,30AE8@2,3F80H@33958,4IGBF@91061 NA|NA|NA S Bacteriophage holin of superfamily 6 (Holin_LLH) LEHHPAIP_01016 349123.Lreu23DRAFT_3849 1.7e-183 648.7 Lactobacillaceae ps461 3.5.1.104 ko:K07273,ko:K22278 ko00000,ko01000 Bacteria 1V3SH@1239,3F6ZF@33958,4HNR1@91061,COG1388@1,COG1388@2,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 LEHHPAIP_01017 557436.Lreu_0779 0.0 1367.4 Lactobacillaceae topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1TPUS@1239,3F3VS@33958,4HA6C@91061,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone LEHHPAIP_01018 557436.Lreu_0780 1.4e-164 585.5 Lactobacillaceae lacX 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1U26T@1239,3F3KT@33958,4HA4J@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase LEHHPAIP_01019 349123.Lreu23DRAFT_3202 1.2e-104 386.0 Lactobacillaceae plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,3.5.1.104 ko:K08591,ko:K22278 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VA3J@1239,3FCBC@33958,4HHUW@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP LEHHPAIP_01020 557436.Lreu_1005 3.4e-172 610.9 Lactobacillaceae Bacteria 1U58X@1239,29NMY@1,309JW@2,3F570@33958,4IF08@91061 NA|NA|NA LEHHPAIP_01021 557436.Lreu_1006 1.8e-43 181.4 Lactobacillaceae Bacteria 1U5Q9@1239,2BZ0D@1,309UA@2,3F6B1@33958,4IFEF@91061 NA|NA|NA LEHHPAIP_01022 349123.Lreu23DRAFT_3799 2.9e-20 103.6 Lactobacillaceae Bacteria 1U5Q9@1239,2BZ0D@1,309UA@2,3F6B1@33958,4IFEF@91061 NA|NA|NA LEHHPAIP_01023 349123.Lreu23DRAFT_3796 0.0 1169.5 Lactobacillaceae Bacteria 1U6IR@1239,3F76G@33958,4HMS0@91061,COG3012@1,COG3012@2 NA|NA|NA S SEC-C Motif Domain Protein LEHHPAIP_01024 349123.Lreu23DRAFT_3795 2e-49 201.4 Lactobacillaceae Bacteria 1U7Z8@1239,29QEM@1,30BDZ@2,3FACJ@33958,4IHWK@91061 NA|NA|NA LEHHPAIP_01025 557436.Lreu_1013 8.6e-137 493.0 Lactobacillaceae thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1R6@1239,3F43J@33958,4HFTJ@91061,COG2145@1,COG2145@2 NA|NA|NA H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) LEHHPAIP_01026 557436.Lreu_1014 1.1e-147 529.3 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase LEHHPAIP_01027 557436.Lreu_1015 1.5e-115 422.2 Lactobacillaceae thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3ZR@1239,3F5ZQ@33958,4HH1E@91061,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) LEHHPAIP_01028 349123.Lreu23DRAFT_3791 1.3e-227 795.4 Lactobacillaceae clcA_2 ko:K03281 ko00000 2.A.49 Bacteria 1V07H@1239,3F4QW@33958,4IQYS@91061,COG0038@1,COG0038@2 NA|NA|NA P Chloride transporter, ClC family LEHHPAIP_01029 1154757.Q5C_00855 4.4e-129 468.0 Bacilli Bacteria 1TRSB@1239,4HDPK@91061,COG3547@1,COG3547@2 NA|NA|NA L PFAM transposase IS116 IS110 IS902 LEHHPAIP_01030 557436.Lreu_1017 0.0 1574.3 Lactobacillaceae malZ 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 1TR8N@1239,3F4CE@33958,4HB1D@91061,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family LEHHPAIP_01031 349123.Lreu23DRAFT_3789 9.3e-110 402.9 Lactobacillaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VF2U@1239,3F75K@33958,4HJBQ@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues LEHHPAIP_01032 557436.Lreu_0275 2.3e-41 174.5 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family LEHHPAIP_01033 557436.Lreu_0275 6.4e-90 336.7 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family LEHHPAIP_01034 349123.Lreu23DRAFT_5031 2e-79 301.6 Lactobacillaceae msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1UPN0@1239,3F6H4@33958,4HGWN@91061,COG0229@1,COG0229@2 NA|NA|NA O peptide methionine sulfoxide reductase LEHHPAIP_01035 349123.Lreu23DRAFT_5030 1.9e-102 378.6 Lactobacillaceae proW ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1UHWH@1239,3F5XQ@33958,4HJIP@91061,COG1174@1,COG1174@2 NA|NA|NA P ABC transporter, permease protein LEHHPAIP_01036 349123.Lreu23DRAFT_5029 6.5e-142 510.0 Lactobacillaceae proV ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TPV8@1239,3F55H@33958,4H9SI@91061,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter, ATP-binding protein LEHHPAIP_01037 349123.Lreu23DRAFT_5028 3.1e-105 387.9 Lactobacillaceae proWZ ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1V41S@1239,3FB48@33958,4HH8U@91061,COG1174@1,COG1174@2 NA|NA|NA P ABC transporter permease LEHHPAIP_01038 557436.Lreu_0184 1.7e-162 578.6 Lactobacillaceae proX ko:K05845 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TQ7D@1239,3FB49@33958,4HESS@91061,COG1732@1,COG1732@2 NA|NA|NA M ABC transporter, substrate-binding protein, QAT family LEHHPAIP_01039 349123.Lreu23DRAFT_5026 3.8e-73 280.8 Lactobacillaceae Bacteria 1V6FK@1239,3F73Q@33958,4HKZD@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_01040 557436.Lreu_0182 1.6e-35 154.8 Lactobacillaceae 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1V0UQ@1239,3FB42@33958,4HDP4@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding LEHHPAIP_01042 557436.Lreu_0181 3.7e-221 773.9 Lactobacillaceae 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 R01057,R02749 RC00408 ko00000,ko00001,ko01000 Bacteria 1TP70@1239,3F5Y0@33958,4H9RU@91061,COG1015@1,COG1015@2 NA|NA|NA G Metalloenzyme superfamily LEHHPAIP_01043 557436.Lreu_0180 7.5e-311 1072.4 Lactobacillaceae cadA Bacteria 1TQ07@1239,3F4JI@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase LEHHPAIP_01044 557436.Lreu_0179 1.3e-123 449.1 Lactobacillaceae XK27_08875 Bacteria 1VW9X@1239,3F60X@33958,4HWF8@91061,COG5549@1,COG5549@2 NA|NA|NA O PFAM peptidase M10A and M12B, matrixin and adamalysin LEHHPAIP_01045 557436.Lreu_0178 2.3e-125 454.9 Lactobacillaceae Bacteria 1TX8X@1239,2A0WK@1,30P1Q@2,3F6QW@33958,4I65V@91061 NA|NA|NA LEHHPAIP_01046 557436.Lreu_0177 2.6e-52 211.1 Lactobacillaceae ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1VBI9@1239,3F7IR@33958,4HMY5@91061,COG4095@1,COG4095@2 NA|NA|NA S Sugar efflux transporter for intercellular exchange LEHHPAIP_01047 557436.Lreu_0176 6.1e-244 849.7 Lactobacillaceae merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TP1W@1239,3FC6T@33958,4HBZF@91061,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulfide oxidoreductase LEHHPAIP_01049 349123.Lreu23DRAFT_5017 0.0 1823.5 Lactobacillaceae Bacteria 1TQ62@1239,3F3YQ@33958,4HAJ1@91061,COG1061@1,COG1061@2,COG3886@1,COG3886@2 NA|NA|NA L Helicase C-terminal domain protein LEHHPAIP_01050 557436.Lreu_0173 1.6e-64 252.3 Lactobacillaceae 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 Bacteria 1VB2R@1239,3F7AV@33958,4HM3J@91061,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily LEHHPAIP_01051 557436.Lreu_0172 4.1e-178 630.6 Lactobacillaceae Bacteria 1TQ12@1239,3F4U1@33958,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase LEHHPAIP_01053 557436.Lreu_0171 8.5e-142 509.6 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) LEHHPAIP_01054 349123.Lreu23DRAFT_5013 1.9e-26 124.8 Lactobacillaceae psiE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K13256 ko00000 Bacteria 1VCG5@1239,3FBQN@33958,4HKQN@91061,COG3223@1,COG3223@2 NA|NA|NA S Phosphate-starvation-inducible E LEHHPAIP_01055 349123.Lreu23DRAFT_5012 5.9e-97 360.1 Lactobacillaceae ydeN ko:K07002 ko00000 Bacteria 1V6R4@1239,3FBQF@33958,4HVF4@91061,COG3545@1,COG3545@2 NA|NA|NA S Serine hydrolase LEHHPAIP_01057 349123.Lreu23DRAFT_5010 2.2e-182 644.8 Bacilli Bacteria 1TSGY@1239,4H9WP@91061,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family LEHHPAIP_01058 349123.Lreu23DRAFT_5007 1.2e-253 882.1 Lactobacillaceae nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 1TQ3B@1239,3F3VX@33958,4HA18@91061,COG1757@1,COG1757@2 NA|NA|NA C Na H antiporter NhaC LEHHPAIP_01059 349123.Lreu23DRAFT_5006 2.5e-36 157.5 Bacteria Bacteria COG4892@1,COG4892@2 NA|NA|NA S Cytochrome b5-like Heme/Steroid binding domain LEHHPAIP_01060 349123.Lreu23DRAFT_5005 1.8e-113 415.2 Lactobacillaceae ywnB ko:K07118 ko00000 Bacteria 1TZ3T@1239,3F5K7@33958,4HVUN@91061,COG2910@1,COG2910@2 NA|NA|NA S NAD(P)H-binding LEHHPAIP_01061 557436.Lreu_0163 7e-36 156.0 Lactobacillaceae Bacteria 1U6PW@1239,2BV51@1,32QIB@2,3F89X@33958,4IGGV@91061 NA|NA|NA LEHHPAIP_01062 349123.Lreu23DRAFT_5003 3.3e-127 461.1 Lactobacillaceae Bacteria 1TPHT@1239,3FC9Q@33958,4HVYE@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Dehydrogenase reductase LEHHPAIP_01063 557436.Lreu_0161 4.9e-238 830.1 Lactobacillaceae yhjE Bacteria 1TQIJ@1239,3FCBR@33958,4HAM0@91061,COG0477@1,COG0477@2 NA|NA|NA EGP MFS transporter, metabolite H symporter (MHS) family protein LEHHPAIP_01064 748671.LCRIS_00244 1.9e-18 99.0 Lactobacillaceae 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 1UHXY@1239,3F52E@33958,4ISAC@91061,COG1196@1,COG1196@2,COG3064@1,COG3064@2 NA|NA|NA M Rib/alpha-like repeat LEHHPAIP_01065 349123.Lreu23DRAFT_4763 3.4e-121 441.0 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F5BG@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain LEHHPAIP_01066 557436.Lreu_1587 7.9e-123 446.4 Lactobacillaceae Bacteria 1U5VI@1239,3F6K2@33958,4IFJ8@91061,COG5549@1,COG5549@2 NA|NA|NA O Zinc-dependent metalloprotease LEHHPAIP_01067 349123.Lreu23DRAFT_4534 2.6e-88 331.3 Lactobacillaceae luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1CH@1239,3F4W2@33958,4HFPR@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) LEHHPAIP_01068 557436.Lreu_1585 3.8e-159 567.4 Lactobacillaceae metQ_4 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1V0Z6@1239,3FC6K@33958,4HBBW@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family LEHHPAIP_01071 557436.Lreu_1361 5e-237 826.6 Lactobacillaceae Bacteria 1TR5X@1239,3F57W@33958,4HBD9@91061,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain LEHHPAIP_01072 557436.Lreu_1360 3.2e-130 471.1 Lactobacillaceae Bacteria 1TRWF@1239,3FBJW@33958,4IQXF@91061,COG1484@1,COG1484@2 NA|NA|NA O Bacterial dnaA protein LEHHPAIP_01073 1033837.WANG_1127 8e-153 546.6 Lactobacillaceae tnp2 Bacteria 1TQ93@1239,3F4RB@33958,4HC0Q@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM Transposase, IS204 IS1001 IS1096 IS1165 LEHHPAIP_01074 557436.Lreu_1081 3.8e-85 320.9 Lactobacillaceae yxjG_1 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent LEHHPAIP_01075 557436.Lreu_1083 4.4e-158 563.9 Lactobacillaceae menA 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TSZV@1239,3F3JM@33958,4HA68@91061,COG1575@1,COG1575@2 NA|NA|NA H 1,4-dihydroxy-2-naphthoate LEHHPAIP_01076 349123.Lreu23DRAFT_5169 5.5e-178 630.2 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family LEHHPAIP_01077 257314.LJ_0143 8e-134 485.0 Lactobacillaceae Bacteria 1UJ2D@1239,3F5DF@33958,4ISZI@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation LEHHPAIP_01078 557436.Lreu_1085 0.0 1349.3 Lactobacillaceae lacZ 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 1TQN6@1239,3F3PC@33958,4HARI@91061,COG1874@1,COG1874@2 NA|NA|NA G -beta-galactosidase LEHHPAIP_01079 557436.Lreu_1086 0.0 1237.2 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter LEHHPAIP_01080 557436.Lreu_1087 3e-187 661.0 Lactobacillaceae lacR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_01081 349123.Lreu23DRAFT_5163 3.8e-10 69.7 Lactobacillaceae Bacteria 1U6EP@1239,29PCK@1,30AAU@2,3F7R6@33958,4IG6H@91061 NA|NA|NA LEHHPAIP_01082 557436.Lreu_1090 3.3e-160 570.9 Lactobacillaceae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,3F4GK@33958,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III LEHHPAIP_01083 349123.Lreu23DRAFT_5161 1.2e-52 212.2 Lactobacillaceae Bacteria 1VFER@1239,3F7BQ@33958,4HM4N@91061,COG1694@1,COG1694@2 NA|NA|NA S Mazg nucleotide pyrophosphohydrolase LEHHPAIP_01084 557436.Lreu_1092 8.5e-34 149.1 Lactobacillaceae Bacteria 1U8GZ@1239,2BU6A@1,32PFG@2,3FAZ2@33958,4IIEU@91061 NA|NA|NA LEHHPAIP_01085 557436.Lreu_1149 3.6e-64 250.8 Lactobacillaceae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6FT@1239,3F6K4@33958,4HIK3@91061,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site LEHHPAIP_01086 557436.Lreu_1150 9.9e-261 905.6 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F4XD@33958,4I3H6@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_01087 349123.Lreu23DRAFT_3934 2.2e-142 511.5 Lactobacillaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,3F3NP@33958,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family LEHHPAIP_01088 349123.Lreu23DRAFT_3935 7.6e-91 339.7 Lactobacillaceae rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1V6HD@1239,3F74P@33958,4HH3H@91061,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes LEHHPAIP_01089 557436.Lreu_1153 4.1e-40 170.2 Lactobacillaceae ylqC ko:K06960 ko00000 Bacteria 1VEG7@1239,3F829@33958,4HNX0@91061,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family LEHHPAIP_01090 349123.Lreu23DRAFT_3937 2.2e-44 184.5 Lactobacillaceae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA0X@1239,3F6VV@33958,4HKNN@91061,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family LEHHPAIP_01091 557436.Lreu_1155 1.8e-249 868.2 Lactobacillaceae ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1TP06@1239,3F40R@33958,4H9T4@91061,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY LEHHPAIP_01092 349123.Lreu23DRAFT_3939 1.3e-57 228.8 Lactobacillaceae ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 ko:K09787 ko00000 Bacteria 1VEGP@1239,3F7FG@33958,4HKK6@91061,COG2739@1,COG2739@2 NA|NA|NA S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein LEHHPAIP_01093 349123.Lreu23DRAFT_3940 1.1e-177 629.8 Lactobacillaceae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,3F3YC@33958,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) LEHHPAIP_01094 557436.Lreu_1158 0.0 1599.3 Lactobacillaceae smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,3F478@33958,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning LEHHPAIP_01095 349123.Lreu23DRAFT_3942 1.2e-131 475.7 Lactobacillaceae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1TPGC@1239,3F564@33958,4HAWU@91061,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism LEHHPAIP_01096 349123.Lreu23DRAFT_3943 2.9e-38 164.1 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VEE3@1239,3F7F4@33958,4HNQ0@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis LEHHPAIP_01097 557436.Lreu_1161 1e-187 662.5 Lactobacillaceae plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPXS@1239,3F4N9@33958,4HA0R@91061,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA LEHHPAIP_01098 557436.Lreu_1162 0.0 1324.7 Lactobacillaceae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TQ6I@1239,3F3JW@33958,4HAWN@91061,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) LEHHPAIP_01099 557436.Lreu_1163 0.0 1082.0 Lactobacillaceae yloV ko:K07030 ko00000 Bacteria 1TQMX@1239,3F3X0@33958,4HBSE@91061,COG1461@1,COG1461@2 NA|NA|NA S DAK2 domain fusion protein YloV LEHHPAIP_01100 349123.Lreu23DRAFT_3947 4.7e-58 230.3 Lactobacillaceae asp Bacteria 1V731@1239,3F72W@33958,4HIS4@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function LEHHPAIP_01101 349123.Lreu23DRAFT_3948 7e-26 122.5 Lactobacillaceae rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TVQH@1239,3FCDR@33958,4HSV0@91061,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family LEHHPAIP_01102 557436.Lreu_1166 2.4e-121 441.4 Lactobacillaceae thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VA0W@1239,3F4N8@33958,4HHS1@91061,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase LEHHPAIP_01103 349123.Lreu23DRAFT_3950 4.2e-118 430.6 Lactobacillaceae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,3F4KX@33958,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family LEHHPAIP_01104 349123.Lreu23DRAFT_3951 1.5e-161 575.5 Lactobacillaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TPSQ@1239,3F3XH@33958,4HA9W@91061,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit LEHHPAIP_01105 557436.Lreu_1169 0.0 1225.3 Lactobacillaceae Bacteria 1TP3F@1239,3F4G6@33958,4H9KD@91061,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase LEHHPAIP_01106 557436.Lreu_1170 6.1e-129 466.8 Lactobacillaceae stp 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1V6K5@1239,3F4UI@33958,4HCDR@91061,COG0631@1,COG0631@2 NA|NA|NA T phosphatase LEHHPAIP_01107 557436.Lreu_1171 2e-247 861.3 Lactobacillaceae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TP3N@1239,3F45F@33958,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA LEHHPAIP_01108 349123.Lreu23DRAFT_3955 6.7e-173 613.2 Lactobacillaceae fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 iSB619.SA_RS06010 Bacteria 1TQ32@1239,3F4N7@33958,4HART@91061,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus LEHHPAIP_01109 557436.Lreu_1173 0.0 1588.9 Lactobacillaceae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TNYB@1239,3F3N8@33958,4H9WW@91061,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA LEHHPAIP_01110 557436.Lreu_1174 1.3e-208 732.3 Lactobacillaceae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPP3@1239,3F3XX@33958,4HAK8@91061,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine LEHHPAIP_01111 349123.Lreu23DRAFT_3958 7.7e-32 142.5 Lactobacillaceae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1VK74@1239,3F81N@33958,4HNHS@91061,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits LEHHPAIP_01112 349123.Lreu23DRAFT_3959 7.9e-114 416.4 Lactobacillaceae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15680 Bacteria 1TP0M@1239,3F3X9@33958,4HAYW@91061,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP LEHHPAIP_01113 349123.Lreu23DRAFT_3960 4.2e-53 213.8 Lactobacillaceae Bacteria 1U70V@1239,29PTH@1,30ARQ@2,3F8TW@33958,4IGV6@91061 NA|NA|NA LEHHPAIP_01114 557436.Lreu_1178 6.1e-262 909.8 Lactobacillaceae recN GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 1TP99@1239,3F43U@33958,4H9ZR@91061,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA LEHHPAIP_01115 557436.Lreu_1179 7.3e-77 293.1 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,3F71C@33958,4HFY8@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes LEHHPAIP_01116 557436.Lreu_1180 1.2e-149 535.8 Lactobacillaceae rrmJ 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1TPE4@1239,3F45T@33958,4HAPY@91061,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J LEHHPAIP_01117 349123.Lreu23DRAFT_3964 4.9e-154 550.4 Lactobacillaceae ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TPQY@1239,3F436@33958,4HA8E@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family LEHHPAIP_01118 349123.Lreu23DRAFT_3965 1.3e-42 178.7 Lactobacillaceae xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1VK9I@1239,3F81K@33958,4HNRB@91061,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides LEHHPAIP_01119 349123.Lreu23DRAFT_3966 2.6e-215 754.6 Lactobacillaceae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP4E@1239,3F4RE@33958,4HAN2@91061,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides LEHHPAIP_01120 557436.Lreu_1184 1.3e-146 525.8 Lactobacillaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1P@1239,3F46A@33958,4H9Q6@91061,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate LEHHPAIP_01121 349123.Lreu23DRAFT_3968 4.7e-70 270.4 Lactobacillaceae nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1VA9B@1239,3F7KW@33958,4HKMU@91061,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons LEHHPAIP_01122 349123.Lreu23DRAFT_3969 2.2e-70 271.6 Lactobacillaceae yqhY ko:K10947 ko00000,ko03000 Bacteria 1V4IC@1239,3F71X@33958,4HJ7T@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function LEHHPAIP_01123 557436.Lreu_1187 1.7e-114 418.7 Lactobacillaceae Bacteria 1VEKU@1239,3F6IQ@33958,4I0FI@91061,COG1514@1,COG1514@2 NA|NA|NA J 2'-5' RNA ligase superfamily LEHHPAIP_01124 557436.Lreu_1188 7.3e-200 703.0 Lactobacillaceae pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,3F4DR@33958,4HAT7@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain LEHHPAIP_01125 557436.Lreu_1189 2.6e-129 468.0 Lactobacillaceae yggS ko:K06997 ko00000 Bacteria 1TRDN@1239,3F8KS@33958,4HC45@91061,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis LEHHPAIP_01126 349123.Lreu23DRAFT_4043 1.3e-44 185.3 Lactobacillaceae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6HW@1239,3F6WU@33958,4HIMN@91061,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family LEHHPAIP_01127 557436.Lreu_1191 2.4e-53 214.5 Lactobacillaceae ysxB ko:K07584 ko00000 Bacteria 1VEQ9@1239,3F839@33958,4HNMV@91061,COG2868@1,COG2868@2 NA|NA|NA J Cysteine protease Prp LEHHPAIP_01128 349123.Lreu23DRAFT_4045 5.2e-50 203.4 Lactobacillaceae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YH@1239,3F6WT@33958,4HIGK@91061,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 LEHHPAIP_01129 349123.Lreu23DRAFT_4046 7e-110 403.3 Lactobacillaceae Bacteria 1VGVA@1239,3F3TB@33958,4HPAG@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator LEHHPAIP_01132 349123.Lreu23DRAFT_4048 5.7e-86 323.6 Lactobacillaceae dut Bacteria 1VGAY@1239,3F6E4@33958,4HPDT@91061,COG4508@1,COG4508@2 NA|NA|NA S Protein conserved in bacteria LEHHPAIP_01133 557436.Lreu_1195 3e-179 634.4 Lactobacillaceae Bacteria 1VK1W@1239,2F367@1,33W0S@2,3F3MT@33958,4HWH4@91061 NA|NA|NA LEHHPAIP_01134 557436.Lreu_1196 9.7e-150 536.2 Lactobacillaceae Bacteria 1V8SY@1239,2AZ1J@1,31R7P@2,3F4MX@33958,4HJRD@91061 NA|NA|NA LEHHPAIP_01135 557436.Lreu_1197 4.8e-51 206.8 Lactobacillaceae ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein LEHHPAIP_01136 557436.Lreu_1198 4.7e-99 367.1 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1V1MJ@1239,3FBG0@33958,4HG4U@91061,COG0225@1,COG0225@2 NA|NA|NA C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine LEHHPAIP_01137 349123.Lreu23DRAFT_4054 3.9e-12 76.3 Lactobacillaceae Bacteria 1U751@1239,29PWQ@1,30AV2@2,3F8ZI@33958,4IGZQ@91061 NA|NA|NA LEHHPAIP_01138 349123.Lreu23DRAFT_4055 2.3e-41 174.5 Lactobacillaceae patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase LEHHPAIP_01139 349123.Lreu23DRAFT_4055 6.1e-32 142.9 Lactobacillaceae patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase LEHHPAIP_01140 349123.Lreu23DRAFT_4055 3.9e-96 357.5 Lactobacillaceae patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase LEHHPAIP_01141 349123.Lreu23DRAFT_4056 2.2e-295 1020.8 Lactobacillaceae gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iSB619.SA_RS02860 Bacteria 1TPJC@1239,3FCC8@33958,4HTGI@91061,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) LEHHPAIP_01142 557436.Lreu_1202 6.2e-265 919.5 Lactobacillaceae glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1TNZA@1239,3F41A@33958,4HACE@91061,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase LEHHPAIP_01143 557436.Lreu_1203 2e-174 618.2 Lactobacillaceae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1TPSC@1239,3F3XS@33958,4HAVW@91061,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) LEHHPAIP_01144 349123.Lreu23DRAFT_4059 5.9e-22 109.4 Bacilli Bacteria 1TVQX@1239,29KU8@1,307RP@2,4I084@91061 NA|NA|NA S Protein of unknown function (DUF3042) LEHHPAIP_01145 557436.Lreu_1205 3.4e-67 260.8 Lactobacillaceae yqhL Bacteria 1VAI7@1239,3F67E@33958,4HKCE@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like protein LEHHPAIP_01146 557436.Lreu_1206 5.6e-183 646.7 Lactobacillaceae glk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS07790 Bacteria 1TPKW@1239,3F4F0@33958,4HBAU@91061,COG1940@1,COG1940@2 NA|NA|NA G Glucokinase LEHHPAIP_01147 557436.Lreu_1207 7.4e-36 156.0 Lactobacillaceae yqgQ Bacteria 1VK83@1239,3F83I@33958,4HRG2@91061,COG4483@1,COG4483@2 NA|NA|NA S Bacterial protein of unknown function (DUF910) LEHHPAIP_01148 557436.Lreu_1208 1.6e-19 101.3 Lactobacillaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,3F3WR@33958,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Peptidase, S54 family LEHHPAIP_01149 557436.Lreu_1208 1.6e-74 285.4 Lactobacillaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,3F3WR@33958,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Peptidase, S54 family LEHHPAIP_01150 557436.Lreu_1209 1.8e-101 375.2 Lactobacillaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,3F4KQ@33958,4HM35@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family LEHHPAIP_01151 349123.Lreu23DRAFT_4065 4.2e-21 106.3 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEJ4@1239,3F828@33958,4HNIM@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family LEHHPAIP_01152 349123.Lreu23DRAFT_4066 0.0 1332.0 Lactobacillaceae pbp2b 3.4.16.4 ko:K00687,ko:K05515,ko:K12553,ko:K21465 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQHY@1239,3F3KH@33958,4HAFX@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein LEHHPAIP_01153 557436.Lreu_1212 0.0 1712.2 Lactobacillaceae Bacteria 1TRR1@1239,3F49G@33958,4HBW6@91061,COG4485@1,COG4485@2 NA|NA|NA S membrane LEHHPAIP_01154 557436.Lreu_1213 3.1e-68 264.2 Lactobacillaceae yneR Bacteria 1VEQE@1239,3F7SB@33958,4HNU2@91061,COG4841@1,COG4841@2 NA|NA|NA S Belongs to the HesB IscA family LEHHPAIP_01155 349123.Lreu23DRAFT_4069 5.3e-78 297.0 Lactobacillaceae greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03624 ko00000,ko03021 Bacteria 1V44S@1239,3F4ZF@33958,4HGZU@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides LEHHPAIP_01156 349123.Lreu23DRAFT_4070 2.3e-116 424.9 Lactobacillaceae udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,3F3KE@33958,4HAVR@91061,COG0572@1,COG0572@2 NA|NA|NA F Cytidine monophosphokinase LEHHPAIP_01157 349123.Lreu23DRAFT_4071 3.6e-114 417.5 Lactobacillaceae rlpA ko:K03642,ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VFKC@1239,3F6HG@33958,4IFHN@91061,COG0791@1,COG0791@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM NLP P60 protein LEHHPAIP_01158 557436.Lreu_1217 0.0 1567.4 Lactobacillaceae pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1TP98@1239,3F3V3@33958,4HAQ9@91061,COG0072@1,COG0072@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily LEHHPAIP_01159 557436.Lreu_1218 2.3e-198 698.0 Lactobacillaceae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPFW@1239,3F4NT@33958,4HAVN@91061,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily LEHHPAIP_01160 349123.Lreu23DRAFT_4074 4.4e-58 230.3 Lactobacillaceae yodB Bacteria 1VBI7@1239,3F7FK@33958,4HKBR@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family LEHHPAIP_01161 557436.Lreu_1220 1.2e-91 342.4 Lactobacillaceae XK27_09705 6.1.1.14 ko:K01879,ko:K06950 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V4QX@1239,3F64N@33958,4HHW0@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. LEHHPAIP_01162 557436.Lreu_1221 4.1e-144 517.3 Lactobacillaceae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1V3JP@1239,3F3NF@33958,4HCF5@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family LEHHPAIP_01163 349123.Lreu23DRAFT_4077 1.6e-42 178.3 Firmicutes acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 1VDVJ@1239,COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family LEHHPAIP_01164 557436.Lreu_1223 1.3e-168 599.0 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TSDN@1239,3F3P3@33958,4HCC8@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins LEHHPAIP_01165 557436.Lreu_1224 8.2e-67 259.6 Lactobacillaceae def_1 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V73T@1239,3F6ZA@33958,4HISW@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins LEHHPAIP_01166 557436.Lreu_1225 4.3e-234 817.0 Lactobacillaceae Bacteria 1TP6V@1239,3FBD2@33958,4IPM0@91061,COG0534@1,COG0534@2 NA|NA|NA V MatE LEHHPAIP_01167 557436.Lreu_1226 4.8e-266 923.3 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid LEHHPAIP_01168 557436.Lreu_1227 3.7e-279 966.8 Lactobacillaceae arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPSK@1239,3F3NU@33958,4HAH5@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase LEHHPAIP_01169 557436.Lreu_1228 1.5e-121 442.2 Lactobacillaceae Bacteria 1TS81@1239,3F421@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator LEHHPAIP_01170 349123.Lreu23DRAFT_4084 1.1e-28 131.7 Lactobacillaceae rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VEFI@1239,3FCDY@33958,4HNIZ@91061,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family LEHHPAIP_01171 349123.Lreu23DRAFT_4085 2.9e-99 367.9 Lactobacillaceae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1VB08@1239,3F61Z@33958,4HME9@91061,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 LEHHPAIP_01172 557436.Lreu_1231 1.5e-208 731.9 Lactobacillaceae ylbM Bacteria 1TPP2@1239,3F3QC@33958,4HAZJ@91061,COG1323@1,COG1323@2 NA|NA|NA S Belongs to the UPF0348 family LEHHPAIP_01173 349123.Lreu23DRAFT_4087 1.1e-135 489.2 Lactobacillaceae yqeM Bacteria 1TQUF@1239,3F4KM@33958,4HD2W@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase LEHHPAIP_01174 557436.Lreu_1233 4.9e-60 236.9 Lactobacillaceae rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 1VA2Z@1239,3F7QN@33958,4HKEJ@91061,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation LEHHPAIP_01175 349123.Lreu23DRAFT_4089 2.8e-111 407.9 Lactobacillaceae nadD 2.7.6.3,2.7.7.18 ko:K00950,ko:K00969,ko:K06950 ko00760,ko00790,ko01100,map00760,map00790,map01100 M00115,M00126,M00841 R00137,R03005,R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6Y1@1239,3F47C@33958,4HHRY@91061,COG1713@1,COG1713@2 NA|NA|NA H Hydrolase, HD family LEHHPAIP_01176 349123.Lreu23DRAFT_4090 6.9e-121 439.9 Lactobacillaceae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3SK@1239,3F4D6@33958,4HGXK@91061,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) LEHHPAIP_01177 349123.Lreu23DRAFT_4091 1.9e-47 194.9 Lactobacillaceae yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 1VEGM@1239,3F7EW@33958,4HKC7@91061,COG1534@1,COG1534@2 NA|NA|NA J RNA-binding protein LEHHPAIP_01178 349123.Lreu23DRAFT_4092 2.1e-218 764.6 Lactobacillaceae yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 ko:K06948 ko00000,ko03009 Bacteria 1TPM2@1239,3F4JU@33958,4HAAF@91061,COG1161@1,COG1161@2 NA|NA|NA S Ribosome biogenesis GTPase YqeH LEHHPAIP_01179 349123.Lreu23DRAFT_4093 1.4e-95 355.5 Lactobacillaceae yqeG ko:K07015 ko00000 Bacteria 1V6KM@1239,3F46V@33958,4HGAV@91061,COG2179@1,COG2179@2 NA|NA|NA S HAD phosphatase, family IIIA LEHHPAIP_01180 557436.Lreu_0272 5.6e-84 317.0 Lactobacillaceae Bacteria 1V414@1239,2C5T7@1,2ZU21@2,3F6JK@33958,4HHIP@91061 NA|NA|NA LEHHPAIP_01182 891391.LAC30SC_01360 1.3e-197 695.7 Lactobacillaceae Bacteria 1TTJI@1239,3F4IB@33958,4HDG6@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_01183 891391.LAC30SC_01355 2.3e-22 110.9 Firmicutes Bacteria 1VIF1@1239,2E38H@1,32Y87@2 NA|NA|NA S DNA binding domain, excisionase family LEHHPAIP_01184 637911.AM305_05100 4.3e-09 70.9 Gammaproteobacteria Bacteria 1MXQ6@1224,1SJSR@1236,2DBQZ@1,2ZAHJ@2 NA|NA|NA LEHHPAIP_01186 349123.Lreu23DRAFT_5009 6.1e-171 606.7 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair LEHHPAIP_01187 405566.lhv_2015 9.2e-59 233.4 Lactobacillaceae Bacteria 1UY4S@1239,3FBF8@33958,4HD5D@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain LEHHPAIP_01188 575594.ACOH01000016_gene1578 4e-12 78.6 Lactobacillaceae Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain LEHHPAIP_01189 575594.ACOH01000016_gene1577 2.7e-08 65.5 Bacteria dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease LEHHPAIP_01191 349123.Lreu23DRAFT_3631 4.3e-155 553.9 Lactobacillaceae ko:K07482 ko00000 Bacteria 1TRSF@1239,3FB5X@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Helix-turn-helix domain LEHHPAIP_01192 748671.LCRIS_00244 1.7e-32 146.0 Lactobacillaceae 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 1UHXY@1239,3F52E@33958,4ISAC@91061,COG1196@1,COG1196@2,COG3064@1,COG3064@2 NA|NA|NA M Rib/alpha-like repeat LEHHPAIP_01193 349123.Lreu23DRAFT_4247 6.3e-38 162.9 Lactobacillaceae ykuJ Bacteria 1U6NV@1239,3F87U@33958,4IGFT@91061,COG4703@1,COG4703@2 NA|NA|NA S Protein of unknown function (DUF1797) LEHHPAIP_01194 349123.Lreu23DRAFT_4248 5.1e-179 633.6 Lactobacillaceae mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1UY7Z@1239,3F3UR@33958,4HCG6@91061,COG0392@1,COG0392@2 NA|NA|NA I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms LEHHPAIP_01195 557436.Lreu_1322 1.5e-197 695.3 Lactobacillaceae cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 ko:K13678 R10865 RC00005,RC00049 ko00000,ko01000,ko01003 GT4 Bacteria 1TPSS@1239,3F47X@33958,4HB9F@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein LEHHPAIP_01196 557436.Lreu_1323 4.6e-227 793.5 Lactobacillaceae mgs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPTA@1239,3F4H5@33958,4HA41@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein LEHHPAIP_01197 557436.Lreu_1324 0.0 1095.9 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) LEHHPAIP_01198 349123.Lreu23DRAFT_4252 2.7e-39 167.5 Lactobacillaceae ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,3F6XQ@33958,4HKGA@91061,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein HPR LEHHPAIP_01199 349123.Lreu23DRAFT_4253 6.4e-27 125.9 Lactobacillaceae Bacteria 1U6RE@1239,29PKR@1,30AIX@2,3F8CZ@33958,4IGIU@91061 NA|NA|NA LEHHPAIP_01200 557436.Lreu_1327 0.0 1315.1 Lactobacillaceae clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F3K9@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family LEHHPAIP_01201 557436.Lreu_1328 1.7e-100 372.1 Lactobacillaceae Bacteria 1V2M1@1239,3FCAQ@33958,4HFPD@91061,COG4684@1,COG4684@2 NA|NA|NA S Pfam:DUF3816 LEHHPAIP_01202 557436.Lreu_1329 3e-141 507.7 Lactobacillaceae manA GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,5.3.1.8,5.4.2.8 ko:K01809,ko:K01840,ko:K04035 ko00051,ko00520,ko00860,ko01100,ko01110,ko01130,map00051,map00520,map00860,map01100,map01110,map01130 M00114 R01818,R01819,R06265,R06266,R06267,R10068 RC00376,RC00408,RC00741,RC01491,RC01492,RC03042 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801 Bacteria 1VWMM@1239,3F62Q@33958,4HX8A@91061,COG1482@1,COG1482@2 NA|NA|NA G MucBP domain LEHHPAIP_01203 557436.Lreu_1330 5.5e-116 423.7 Lactobacillaceae Bacteria 1U656@1239,2BVSH@1,30A3J@2,3F72Y@33958,4IFV0@91061 NA|NA|NA LEHHPAIP_01204 349123.Lreu23DRAFT_4259 4.4e-155 553.9 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TS5Y@1239,3F4BF@33958,4HBUA@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein LEHHPAIP_01205 349123.Lreu23DRAFT_4260 6e-64 250.0 Lactobacillaceae gntR1 ko:K07979 ko00000,ko03000 Bacteria 1VAC6@1239,3F721@33958,4HKVW@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family LEHHPAIP_01206 349123.Lreu23DRAFT_4261 0.0 2503.4 Bacteria bamA ko:K07277,ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029 1.B.33 Bacteria COG2849@1,COG2849@2,COG3266@1,COG3266@2 NA|NA|NA GM domain, Protein LEHHPAIP_01207 349123.Lreu23DRAFT_4262 0.0 1788.1 Lactobacillaceae Bacteria 1UV99@1239,2BFPM@1,329I6@2,3F9IG@33958,4IHB4@91061 NA|NA|NA S Peptidase, M23 LEHHPAIP_01208 349123.Lreu23DRAFT_4263 0.0 1408.7 Lactobacillaceae Bacteria 1VB5V@1239,3F3P4@33958,4HN9W@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family LEHHPAIP_01209 349123.Lreu23DRAFT_4264 1.2e-307 1061.6 Lactobacillaceae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1TPYT@1239,3F489@33958,4HADS@91061,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP LEHHPAIP_01210 349123.Lreu23DRAFT_4265 4e-225 787.3 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein LEHHPAIP_01211 349123.Lreu23DRAFT_4266 7.4e-163 580.1 Lactobacillaceae yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter LEHHPAIP_01212 349123.Lreu23DRAFT_4267 0.0 1546.2 Bacteria csd1 3.5.1.28 ko:K01447,ko:K17733,ko:K19117 R04112 RC00064,RC00141 ko00000,ko01000,ko01002,ko01011,ko02048 Bacteria COG4193@1,COG4193@2,COG5632@1,COG5632@2 NA|NA|NA G domain, Protein LEHHPAIP_01213 349123.Lreu23DRAFT_3628 1.6e-109 402.1 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein LEHHPAIP_01214 349123.Lreu23DRAFT_3627 2.8e-101 374.8 Lactobacillaceae Bacteria 1V7UW@1239,3F4YP@33958,4HHH4@91061,COG4478@1,COG4478@2 NA|NA|NA S Protein of unknown function (DUF1461) LEHHPAIP_01215 557436.Lreu_0563 5.5e-133 480.3 Lactobacillaceae nagD 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGM@1239,3F49D@33958,4HA3R@91061,COG0647@1,COG0647@2 NA|NA|NA G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro LEHHPAIP_01216 349123.Lreu23DRAFT_3625 6.6e-93 346.7 Lactobacillaceae yutD Bacteria 1VA85@1239,3F66P@33958,4HKF7@91061,COG4470@1,COG4470@2 NA|NA|NA S Protein of unknown function (DUF1027) LEHHPAIP_01217 557436.Lreu_0561 4.7e-111 407.1 Lactobacillaceae Bacteria 1V35X@1239,3FBJA@33958,4IQV1@91061,COG4186@1,COG4186@2 NA|NA|NA S Calcineurin-like phosphoesterase LEHHPAIP_01218 349123.Lreu23DRAFT_3623 1.3e-221 775.4 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction LEHHPAIP_01219 349123.Lreu23DRAFT_3622 7.9e-143 513.1 Lactobacillaceae ytxK 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TRIQ@1239,3F4CI@33958,4H9SE@91061,COG0827@1,COG0827@2 NA|NA|NA L N-6 DNA Methylase LEHHPAIP_01221 557436.Lreu_0558 1.2e-68 265.8 Lactobacillaceae ko:K02248 M00429 ko00000,ko00002,ko02044 Bacteria 1W67R@1239,2DGNT@1,2ZWQN@2,3F85R@33958,4I06G@91061 NA|NA|NA LEHHPAIP_01222 557436.Lreu_0557 3.2e-41 174.1 Lactobacillaceae Bacteria 1U79U@1239,29Q03@1,30AYJ@2,3F962@33958,4IH4Q@91061 NA|NA|NA LEHHPAIP_01223 557436.Lreu_0556 3.4e-79 300.8 Lactobacillaceae ko:K02246,ko:K02456,ko:K02457,ko:K02679 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1U6NU@1239,3F87R@33958,4IGFS@91061,COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein LEHHPAIP_01224 557436.Lreu_0555 7.1e-47 193.0 Lactobacillaceae comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1VFI9@1239,3F7ZC@33958,4HNNT@91061,COG4537@1,COG4537@2 NA|NA|NA U competence protein ComGC LEHHPAIP_01225 557436.Lreu_0554 5.1e-182 643.7 Lactobacillaceae comGB ko:K02244 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1U00C@1239,3F3S9@33958,4HGUA@91061,COG1459@1,COG1459@2 NA|NA|NA NU type II secretion system LEHHPAIP_01226 557436.Lreu_0553 4.9e-179 633.6 Lactobacillaceae comGA ko:K02243 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1TPGE@1239,3F4HY@33958,4HB0C@91061,COG2804@1,COG2804@2 NA|NA|NA NU Type II IV secretion system protein LEHHPAIP_01227 349123.Lreu23DRAFT_3614 5.9e-132 476.9 Lactobacillaceae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 1TPP5@1239,3F4WF@33958,4H9WJ@91061,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein LEHHPAIP_01228 557436.Lreu_0551 3.3e-131 474.6 Lactobacillaceae Bacteria 1W6BV@1239,28T2R@1,2ZFBY@2,3F7CC@33958,4HZQK@91061 NA|NA|NA LEHHPAIP_01229 349123.Lreu23DRAFT_3612 7.1e-181 639.8 Lactobacillaceae ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4AA@33958,4H9NG@91061,COG1609@1,COG1609@2 NA|NA|NA K catabolite control protein A LEHHPAIP_01230 557436.Lreu_0549 3.6e-210 737.3 Lactobacillaceae pepQ 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ6R@1239,3F3X5@33958,4HA5I@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain LEHHPAIP_01231 349123.Lreu23DRAFT_3610 3e-25 121.7 Lactobacillaceae Bacteria 1U6NM@1239,2DKRN@1,30AH6@2,3F87G@33958,4IGFK@91061 NA|NA|NA LEHHPAIP_01232 349123.Lreu23DRAFT_3609 6.5e-38 163.7 Lactobacillaceae WQ51_05790 Bacteria 1VAXN@1239,3F6KB@33958,4HM93@91061,COG4768@1,COG4768@2 NA|NA|NA S protein containing a divergent version of the methyl-accepting chemotaxis-like domain LEHHPAIP_01233 557436.Lreu_0546 3.4e-147 527.7 Lactobacillaceae ykuT GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1TR9Z@1239,3F49U@33958,4HCB8@91061,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel LEHHPAIP_01234 349123.Lreu23DRAFT_3607 1.8e-153 548.5 Lactobacillaceae 3.1.3.102,3.1.3.104,3.1.3.23 ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R00804,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UYU8@1239,3F5E3@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase LEHHPAIP_01235 557436.Lreu_0544 1.1e-74 285.8 Lactobacillaceae ykuL Bacteria 1V9HN@1239,3F678@33958,4HH3X@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain LEHHPAIP_01236 557436.Lreu_0543 1.7e-93 348.6 Lactobacillaceae ko:K07095 ko00000 Bacteria 1VA0U@1239,3F73R@33958,4HM24@91061,COG0622@1,COG0622@2 NA|NA|NA S Phosphoesterase LEHHPAIP_01237 557436.Lreu_0542 3.7e-105 387.5 Lactobacillaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1V6RN@1239,3F3KD@33958,4HCP6@91061,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions LEHHPAIP_01238 557436.Lreu_0541 3.1e-147 527.7 Lactobacillaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 1TPPR@1239,3F446@33958,4HA46@91061,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis LEHHPAIP_01239 557436.Lreu_0540 3e-96 357.8 Lactobacillaceae yslB Bacteria 1VD7N@1239,3F7ZI@33958,4HKV3@91061,COG1719@1,COG1719@2 NA|NA|NA S Protein of unknown function (DUF2507) LEHHPAIP_01240 349123.Lreu23DRAFT_3601 6.1e-54 216.5 Lactobacillaceae trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F6Y3@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family LEHHPAIP_01241 557436.Lreu_0538 0.0 1505.3 Lactobacillaceae mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TP5W@1239,3F4DX@33958,4H9NZ@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity LEHHPAIP_01242 349123.Lreu23DRAFT_3599 2.7e-86 324.7 Lactobacillaceae cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1V7U0@1239,3F643@33958,4HIUU@91061,COG1286@1,COG1286@2 NA|NA|NA S Colicin V production protein LEHHPAIP_01243 349123.Lreu23DRAFT_3598 6.1e-48 196.4 Lactobacillaceae yrzB Bacteria 1VAPW@1239,3F6X3@33958,4HKV7@91061,COG3906@1,COG3906@2 NA|NA|NA S Belongs to the UPF0473 family LEHHPAIP_01244 349123.Lreu23DRAFT_3597 3.6e-76 290.8 Lactobacillaceae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1V6ER@1239,3F6NI@33958,4HH04@91061,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA LEHHPAIP_01245 349123.Lreu23DRAFT_3596 4.1e-43 180.3 Lactobacillaceae yrzL Bacteria 1VAC4@1239,3F7EG@33958,4HKD0@91061,COG4472@1,COG4472@2 NA|NA|NA S Belongs to the UPF0297 family LEHHPAIP_01246 557436.Lreu_0533 0.0 1762.3 Lactobacillaceae alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPK6@1239,3F3QS@33958,4H9XC@91061,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain LEHHPAIP_01247 349123.Lreu23DRAFT_3593 3.7e-233 813.9 Lactobacillaceae cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K18692 ko00000,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F4FQ@33958,4HA98@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures LEHHPAIP_01248 557436.Lreu_0531 2.1e-182 644.8 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F4FC@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain protein LEHHPAIP_01249 349123.Lreu23DRAFT_3591 6.2e-31 140.6 Lactobacillaceae yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEMC@1239,3F7EY@33958,4HNK0@91061,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase LEHHPAIP_01250 557436.Lreu_0529 1.7e-188 665.2 Lactobacillaceae tgt_1 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 1TNZ4@1239,3F43F@33958,4HCNM@91061,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) LEHHPAIP_01251 349123.Lreu23DRAFT_3588 1.3e-187 662.1 Lactobacillaceae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TR47@1239,3F47S@33958,4HBMW@91061,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing LEHHPAIP_01252 557436.Lreu_0527 4.3e-101 374.0 Lactobacillaceae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V3KF@1239,3F42W@33958,4HHI5@91061,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB LEHHPAIP_01253 557436.Lreu_0526 0.0 1306.2 Lactobacillaceae mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPGK@1239,3F3PK@33958,4HB34@91061,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex LEHHPAIP_01254 557436.Lreu_0525 0.0 1697.2 Lactobacillaceae mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPRJ@1239,3F4A5@33958,4HA63@91061,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity LEHHPAIP_01255 349123.Lreu23DRAFT_3583 9.5e-209 733.0 Lactobacillaceae rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,3F3WX@33958,4HC9J@91061,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay LEHHPAIP_01256 557436.Lreu_0523 1.7e-196 691.8 Lactobacillaceae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,3F3KU@33958,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage LEHHPAIP_01257 349123.Lreu23DRAFT_3581 8.1e-227 792.7 Lactobacillaceae cinA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1TQ1N@1239,3F4I4@33958,4HATN@91061,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family LEHHPAIP_01258 349123.Lreu23DRAFT_3580 2.5e-101 374.8 Lactobacillaceae pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iSB619.SA_RS06365 Bacteria 1V6PJ@1239,3F4BI@33958,4HCEX@91061,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family LEHHPAIP_01259 349123.Lreu23DRAFT_3579 1.2e-135 489.6 Lactobacillaceae ymfM ko:K15539 ko00000 Bacteria 1V9EA@1239,3FC82@33958,4HPRN@91061,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain LEHHPAIP_01260 557436.Lreu_0519 2.3e-248 864.4 Lactobacillaceae ymfH ko:K07263 ko00000,ko01000,ko01002 Bacteria 1TP5I@1239,3F4MU@33958,4H9YG@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 LEHHPAIP_01261 557436.Lreu_0518 5.3e-226 790.0 Lactobacillaceae ymfF Bacteria 1TPN6@1239,3F3SA@33958,4H9P5@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 inactive domain protein LEHHPAIP_01262 349123.Lreu23DRAFT_3576 2.5e-158 564.7 Lactobacillaceae aatB ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQNR@1239,3F3WC@33958,4HF14@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein LEHHPAIP_01263 557436.Lreu_0516 1.2e-117 429.1 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1UYAZ@1239,3FC39@33958,4HFTM@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein LEHHPAIP_01264 349123.Lreu23DRAFT_3574 3.2e-102 377.9 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1V280@1239,3F3VF@33958,4HGMH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease LEHHPAIP_01265 349123.Lreu23DRAFT_3573 8.7e-93 346.3 Lactobacillaceae mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1VEV7@1239,3F6PG@33958,4HPAC@91061,COG2891@1,COG2891@2 NA|NA|NA M rod shape-determining protein MreD LEHHPAIP_01266 349123.Lreu23DRAFT_3572 3.5e-152 544.3 Lactobacillaceae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1TR1V@1239,3F3MC@33958,4HB0K@91061,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape LEHHPAIP_01267 349123.Lreu23DRAFT_3571 1.7e-179 635.2 Lactobacillaceae mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F3ZV@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D cell shape determining protein MreB LEHHPAIP_01268 557436.Lreu_0511 1.8e-121 441.8 Lactobacillaceae radC ko:K03630 ko00000 Bacteria 1TQ3K@1239,3F5IM@33958,4HB1W@91061,COG2003@1,COG2003@2 NA|NA|NA L DNA repair protein LEHHPAIP_01269 349123.Lreu23DRAFT_3569 7.2e-242 842.8 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F498@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family LEHHPAIP_01270 557436.Lreu_0509 1.8e-231 808.1 Lactobacillaceae ndh GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TR6X@1239,3F4N1@33958,4HA14@91061,COG1252@1,COG1252@2 NA|NA|NA C NADH dehydrogenase LEHHPAIP_01271 557436.Lreu_0508 0.0 1130.9 Lactobacillaceae cydD ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1UHN5@1239,3F4PG@33958,4HAAB@91061,COG4987@1,COG4987@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC LEHHPAIP_01272 557436.Lreu_0507 2.3e-311 1074.3 Lactobacillaceae cydD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1TQ1P@1239,3F451@33958,4HAN0@91061,COG4988@1,COG4988@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD LEHHPAIP_01273 349123.Lreu23DRAFT_3565 4.5e-183 647.1 Lactobacillaceae cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120 Bacteria 1TRYV@1239,3F40S@33958,4H9KF@91061,COG1294@1,COG1294@2 NA|NA|NA C Cytochrome d ubiquinol oxidase subunit II LEHHPAIP_01274 557436.Lreu_0505 1.5e-272 944.9 Lactobacillaceae cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 1TRH4@1239,3F4MJ@33958,4HA19@91061,COG1271@1,COG1271@2 NA|NA|NA C ubiquinol oxidase LEHHPAIP_01275 349123.Lreu23DRAFT_3563 0.0 1746.1 Lactobacillaceae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1TPN4@1239,3F3RB@33958,4HB85@91061,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner LEHHPAIP_01276 349123.Lreu23DRAFT_3562 3.2e-228 797.3 Lactobacillaceae thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07461 ko00000,ko00001,ko01000,ko03016 iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 Bacteria 1TPNW@1239,3F3N0@33958,4HAV9@91061,COG0301@1,COG0301@2 NA|NA|NA H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS LEHHPAIP_01277 557436.Lreu_0502 2.3e-215 754.6 Lactobacillaceae iscS2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F4CD@33958,4HAEE@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V LEHHPAIP_01278 557436.Lreu_0501 3.4e-244 850.9 Lactobacillaceae ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 ko:K06286,ko:K07158 ko00000,ko03036 Bacteria 1TQR7@1239,3F47K@33958,4HA15@91061,COG4477@1,COG4477@2 NA|NA|NA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization LEHHPAIP_01279 349123.Lreu23DRAFT_3558 3.7e-108 397.5 Lactobacillaceae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TR0J@1239,3F3P0@33958,4HAC9@91061,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit LEHHPAIP_01280 557436.Lreu_1584 1.3e-72 278.9 Lactobacillaceae ko:K07482 ko00000 Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region LEHHPAIP_01281 349123.Lreu23DRAFT_5152 1.6e-171 608.6 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F4AU@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA G Responsible for synthesis of pseudouridine from uracil LEHHPAIP_01282 557436.Lreu_0573 1.5e-152 545.4 Lactobacillaceae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1TRB3@1239,3F45D@33958,4HB08@91061,COG0061@1,COG0061@2 NA|NA|NA F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP LEHHPAIP_01283 557436.Lreu_0572 2e-115 421.8 Lactobacillaceae yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F452@33958,4HA3Q@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein LEHHPAIP_01284 349123.Lreu23DRAFT_5149 3.1e-113 414.5 Lactobacillaceae yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TQ8K@1239,3F6QR@33958,4HAI8@91061,COG2761@1,COG2761@2 NA|NA|NA Q Thioredoxin LEHHPAIP_01285 349123.Lreu23DRAFT_5148 1.4e-267 928.3 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase LEHHPAIP_01286 557436.Lreu_0569 2.6e-194 684.5 Lactobacillaceae coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,3F4BZ@33958,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein LEHHPAIP_01287 557436.Lreu_0568 6.7e-119 433.3 Lactobacillaceae mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K16511 ko00000 Bacteria 1UZ7D@1239,3F5G4@33958,4HID6@91061,COG4862@1,COG4862@2 NA|NA|NA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis LEHHPAIP_01288 349123.Lreu23DRAFT_5145 2.7e-67 261.2 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6HJ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress LEHHPAIP_01289 557436.Lreu_0566 8.8e-76 289.7 Lactobacillaceae traP GO:0005575,GO:0016020 1.14.99.57,6.2.1.3 ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1V501@1239,3F3UU@33958,4HHA2@91061,COG2329@1,COG2329@2 NA|NA|NA S enzyme involved in biosynthesis of extracellular polysaccharides LEHHPAIP_01290 525309.HMPREF0494_1214 6.1e-181 640.2 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent LEHHPAIP_01291 1297534.CAUJ01000005_gene97 5.3e-124 451.4 Bacilli repE Bacteria 1UBUD@1239,4HB0A@91061,COG1959@1,COG1959@2 NA|NA|NA K Primase C terminal 1 (PriCT-1) LEHHPAIP_01293 1035189.HMPREF9954_1860 1.8e-11 75.9 Streptococcus infantis Bacteria 1TWK7@1239,2DIZC@1,304ED@2,43GH6@68892,4I5DW@91061 NA|NA|NA S Thioredoxin LEHHPAIP_01295 1035189.HMPREF9954_1861 9.7e-07 60.8 Streptococcus infantis Bacteria 1TWJQ@1239,2DIZ5@1,304E3@2,43GFN@68892,4I5D8@91061 NA|NA|NA LEHHPAIP_01296 997830.HMPREF1124_0834 2.3e-27 129.8 Streptococcus infantis Bacteria 1W27X@1239,2DCHT@1,2ZE7E@2,43GGG@68892,4I25E@91061 NA|NA|NA LEHHPAIP_01301 1074451.CRL705_1887 9.5e-156 556.2 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair LEHHPAIP_01303 211110.gbs0382 9.3e-29 134.0 Bacilli ada 3.2.2.21 ko:K13529,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 1TR37@1239,4HHHQ@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA/RNA non-specific endonuclease LEHHPAIP_01305 997830.HMPREF1124_0825 6.7e-11 74.3 Streptococcus infantis Bacteria 1TWKB@1239,2BKU4@1,32FAD@2,43GHI@68892,4I5E1@91061 NA|NA|NA LEHHPAIP_01306 1161413.HMPREF1510_1730 3.4e-125 456.1 Bacilli ruvB 3.6.4.12 ko:K03551,ko:K07126 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V0DS@1239,4HENV@91061,COG2255@1,COG2255@2 NA|NA|NA L four-way junction helicase activity LEHHPAIP_01310 1121865.OMW_00624 1.9e-76 295.4 Firmicutes Bacteria 1VSR7@1239,2EYQW@1,33RY9@2 NA|NA|NA LEHHPAIP_01314 203123.OEOE_0093 1.8e-194 686.0 Leuconostocaceae traI 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 1TPJD@1239,4AYEZ@81850,4HAZV@91061,COG0550@1,COG0550@2 NA|NA|NA L C-terminal repeat of topoisomerase LEHHPAIP_01318 482234.SCAZ3_00280 3.9e-188 664.8 Bacilli clpB ko:K03694,ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Bacteria 1TPMU@1239,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family LEHHPAIP_01321 1403946.Q615_SPAC00114G0040 2.5e-16 94.4 Streptococcus anginosus group Bacteria 1TW0G@1239,2DIU0@1,3044E@2,42EHD@671232,4I4P6@91061 NA|NA|NA LEHHPAIP_01322 1123315.AUIP01000020_gene2240 4e-264 917.9 Bacilli ko:K03205 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1TPCF@1239,4H9ZN@91061,COG3505@1,COG3505@2 NA|NA|NA U COG3505 Type IV secretory pathway, VirD4 components LEHHPAIP_01323 883168.HMPREF9318_00143 2.7e-89 337.0 Bacteria Bacteria 2DF83@1,2ZQUZ@2 NA|NA|NA LEHHPAIP_01325 1423806.JCM15457_1771 3e-23 117.5 Lactobacillaceae Bacteria 1W39C@1239,3F754@33958,4I0DV@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation LEHHPAIP_01329 1140001.I571_02880 5e-29 134.8 Bacteria 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria COG3764@1,COG3764@2 NA|NA|NA M Sortase family LEHHPAIP_01330 1140001.I571_02879 5.6e-85 322.4 Enterococcaceae Bacteria 1TSCY@1239,4B3DY@81852,4I2HB@91061,COG4932@1,COG4932@2 NA|NA|NA M Gram-positive pilin backbone subunit 2, Cna-B-like domain LEHHPAIP_01331 1140001.I571_02252 4.7e-43 181.8 Enterococcaceae 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1UN9R@1239,4B6AY@81852,4HH56@91061,COG3764@1,COG3764@2 NA|NA|NA M Sortase family LEHHPAIP_01335 1033837.WANG_1100 1.9e-30 138.7 Lactobacillaceae higB-2 Bacteria 1U5P8@1239,3FAI9@33958,4II1M@91061,COG4737@1,COG4737@2 NA|NA|NA S RelE toxin of RelE / RelB toxin-antitoxin system LEHHPAIP_01336 1033837.WANG_1099 3.8e-21 107.5 Lactobacillaceae ko:K07726 ko00000,ko03000 Bacteria 1VEWZ@1239,3F82N@33958,4HP6G@91061,COG2944@1,COG2944@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins LEHHPAIP_01339 86416.Clopa_3153 3.3e-21 107.8 Clostridiaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,24HF9@186801,36IQ6@31979,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein LEHHPAIP_01346 1122147.AUEH01000001_gene517 3e-08 65.1 Lactobacillaceae Bacteria 1U74E@1239,29PW7@1,30AUI@2,3F8YN@33958,4IGZ1@91061 NA|NA|NA LEHHPAIP_01348 334390.LAF_0059 6.9e-67 260.4 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family LEHHPAIP_01350 1235801.C822_01042 1.1e-86 326.6 Lactobacillaceae endA ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease LEHHPAIP_01353 1235801.C822_00307 3e-126 458.4 Lactobacillaceae ko:K18640 ko00000,ko04812 Bacteria 1UJAK@1239,3FBWM@33958,4ITM7@91061,COG4972@1,COG4972@2 NA|NA|NA NU StbA protein LEHHPAIP_01355 388919.SSA_0155 5.2e-07 60.5 Streptococcus sanguinis Bacteria 1UACV@1239,1WS5P@1305,2AR9W@1,31GJT@2,4IKR3@91061 NA|NA|NA S Uncharacterized protein pXO2-11 LEHHPAIP_01356 1235801.C822_00299 9.7e-38 163.7 Lactobacillaceae Bacteria 1U7XV@1239,2BNGP@1,32H4W@2,3FAB0@33958,4IHV8@91061 NA|NA|NA LEHHPAIP_01357 1214217.ALNF01000025_gene946 4.2e-230 804.3 Bacilli trsE Bacteria 1W186@1239,4HA4T@91061,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase LEHHPAIP_01359 1033837.WANG_p1172 1.2e-28 134.4 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VW67@1239,3F41W@33958,4HWSY@91061,COG0791@1,COG0791@2 NA|NA|NA M CHAP domain LEHHPAIP_01361 1329250.WOSG25_070410 1.8e-07 63.2 Leuconostocaceae Bacteria 1U3C1@1239,29MH1@1,308EW@2,4AXH6@81850,4ID48@91061 NA|NA|NA LEHHPAIP_01362 1235801.C822_00292 1.7e-100 373.2 Lactobacillaceae Bacteria 1UIMF@1239,2AQ9M@1,31FFI@2,3FBVB@33958,4ISND@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) LEHHPAIP_01363 1284775.HMPREF1640_10930 3.9e-14 85.5 Bacteroidia Bacteria 2FTG5@200643,4NZ8H@976,COG3274@1,COG3274@2 NA|NA|NA S enterobacterial common antigen metabolic process LEHHPAIP_01364 557436.Lreu_1346 0.0 1307.7 Lactobacillaceae gtfC GO:0005575,GO:0005576 2.4.1.5 ko:K00689,ko:K20276 ko00500,ko02020,ko02024,map00500,map02020,map02024 R02120,R06066 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1VQXK@1239,3F93W@33958,4HEIA@91061,COG0366@1,COG0366@2,COG5263@1,COG5263@2 NA|NA|NA G Glycosyl hydrolase family 70 LEHHPAIP_01365 1033837.WANG_1127 8e-153 546.6 Lactobacillaceae tnp2 Bacteria 1TQ93@1239,3F4RB@33958,4HC0Q@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM Transposase, IS204 IS1001 IS1096 IS1165 LEHHPAIP_01366 349123.Lreu23DRAFT_3221 2.4e-22 110.9 Lactobacillaceae Bacteria 1U6N8@1239,29PIT@1,30AGY@2,3F86M@33958,4IGF8@91061 NA|NA|NA LEHHPAIP_01367 349123.Lreu23DRAFT_3219 2.9e-96 357.8 Lactobacillaceae Bacteria 1V8P4@1239,3F65X@33958,4HVM8@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain LEHHPAIP_01368 349123.Lreu23DRAFT_3218 1.7e-295 1021.1 Lactobacillaceae gntK 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family LEHHPAIP_01369 349123.Lreu23DRAFT_3217 7.8e-16 89.0 Lactobacillaceae gntT GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015128,GO:0015144,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K03299,ko:K06155 ko00000,ko02000 2.A.8,2.A.8.1.4 Bacteria 1TQ14@1239,3F3V0@33958,4HB0Y@91061,COG2610@1,COG2610@2 NA|NA|NA EG Gluconate LEHHPAIP_01370 272621.LBA1405 2.7e-23 114.8 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1U5ST@1239,3F841@33958,4IEKF@91061,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system LEHHPAIP_01371 1408287.AXUR01000081_gene2181 1.9e-11 75.1 Bacteria ko:K07172 ko00000,ko02048 Bacteria COG2336@1,COG2336@2 NA|NA|NA T PFAM SpoVT AbrB LEHHPAIP_01372 349123.Lreu23DRAFT_3975 2.2e-176 624.8 Lactobacillaceae ko:K07273 ko00000 Bacteria 1UV96@1239,3F7BC@33958,4IFZR@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 LEHHPAIP_01373 349123.Lreu23DRAFT_3976 2.6e-45 188.3 Lactobacillaceae Bacteria 1U6IX@1239,29PG3@1,30AE8@2,3F80H@33958,4IGBF@91061 NA|NA|NA S Bacteriophage holin of superfamily 6 (Holin_LLH) LEHHPAIP_01374 1567453.A0A0A1ENR5_9CAUD 1.3e-31 142.5 Siphoviridae Viruses 4QFX5@10239,4QMC7@10699,4QRBG@28883 NA|NA|NA LEHHPAIP_01376 1329250.WOSG25_020250 1e-11 78.6 Bacilli Bacteria 1VK4J@1239,2EK2P@1,33DT4@2,4I15W@91061 NA|NA|NA S by MetaGeneAnnotator LEHHPAIP_01380 575594.ACOH01000003_gene776 5.2e-41 175.3 Lactobacillaceae Bacteria 1UV2A@1239,29WTK@1,30IEZ@2,3F6DE@33958,4I41W@91061 NA|NA|NA S Domain of unknown function (DUF2479) LEHHPAIP_01383 349123.Lreu23DRAFT_3983 9.9e-21 106.7 Bacilli ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VW67@1239,4HWSY@91061,COG0791@1,COG0791@2,COG3953@1,COG3953@2 NA|NA|NA M CHAP domain LEHHPAIP_01384 1123318.KB904586_gene441 0.0 1256.1 Bacilli tetP ko:K18220 br01600,ko00000,ko01504 Bacteria 1TPQH@1239,4HAS9@91061,COG0480@1,COG0480@2 NA|NA|NA J elongation factor G LEHHPAIP_01385 391295.SSU05_0923 3e-69 267.7 Bacilli Bacteria 1TQX2@1239,28IGH@1,2Z8HY@2,4HA00@91061 NA|NA|NA S Conjugative transposon protein TcpC LEHHPAIP_01388 908339.HMPREF9265_1401 5.2e-143 513.8 Lactobacillaceae Bacteria 1TP8S@1239,3F4QA@33958,4HCBZ@91061,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein LEHHPAIP_01389 908339.HMPREF9265_1402 8.3e-34 149.8 Lactobacillaceae Bacteria 1U7SI@1239,29QAK@1,30B9S@2,3FA44@33958,4IHPX@91061 NA|NA|NA LEHHPAIP_01390 575594.ACOH01000016_gene1578 3.6e-07 62.0 Lactobacillaceae Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain LEHHPAIP_01391 1298598.JCM21714_2814 1.9e-185 656.0 Bacilli sthIM 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 1TR8A@1239,4HBP1@91061,COG2189@1,COG2189@2 NA|NA|NA L Adenine specific DNA methylase Mod LEHHPAIP_01392 575594.ACOH01000019_gene1495 0.0 1248.4 Lactobacillaceae res_1 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 1TRVK@1239,3F61Y@33958,4HAVG@91061,COG3421@1,COG3421@2 NA|NA|NA L Type III restriction enzyme, res subunit LEHHPAIP_01393 1136177.KCA1_0105 1.6e-42 178.7 Lactobacillaceae hxlR Bacteria 1VA9M@1239,3F7S1@33958,4HH0A@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family LEHHPAIP_01394 944562.HMPREF9102_2154 7.5e-162 576.6 Lactobacillaceae qor 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TRNC@1239,3F48F@33958,4HATC@91061,COG0604@1,COG0604@2 NA|NA|NA C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily LEHHPAIP_01395 387344.LVIS_A11 2.4e-71 275.0 Lactobacillaceae Bacteria 1W1Q8@1239,3F7V4@33958,4I0U9@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain LEHHPAIP_01397 1232666.JANE01000002_gene733 6e-93 346.7 Staphylococcaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974,ko:K19545 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko01504,ko03016,ko03019 Bacteria 1TV2B@1239,4H0P1@90964,4IJI1@91061,COG0617@1,COG0617@2 NA|NA|NA J Aminoglycoside-2''-adenylyltransferase LEHHPAIP_01398 60520.HR47_03405 3.7e-31 140.6 Lactobacillaceae Bacteria 1VGSH@1239,3F84H@33958,4HQ68@91061,COG3877@1,COG3877@2 NA|NA|NA S Protein of unknown function (DUF2089) LEHHPAIP_01399 60520.HR47_03410 9.3e-28 129.4 Lactobacillaceae Bacteria 1VYT7@1239,2FGRX@1,348MC@2,3F8YI@33958,4HY30@91061 NA|NA|NA LEHHPAIP_01402 525309.HMPREF0494_1087 5.7e-90 337.0 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase LEHHPAIP_01404 349123.Lreu23DRAFT_4476 2.8e-162 578.6 Lactobacillaceae lsa ko:K06158,ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000,ko03012 3.A.1.121 Bacteria 1TNYS@1239,3F53D@33958,4HBFK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter LEHHPAIP_01405 557436.Lreu_1549 3e-133 481.1 Lactobacillaceae Bacteria 1TP1H@1239,3F43I@33958,4HFZ9@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold LEHHPAIP_01406 349123.Lreu23DRAFT_4478 4e-179 634.0 Lactobacillaceae MA20_14895 Bacteria 1TQYA@1239,3F4TY@33958,4HCCP@91061,COG2855@1,COG2855@2 NA|NA|NA S Conserved hypothetical protein 698 LEHHPAIP_01407 349123.Lreu23DRAFT_4480 1.2e-94 352.4 Lactobacillaceae Bacteria 1V955@1239,3F4UW@33958,4IEX8@91061,COG0655@1,COG0655@2 NA|NA|NA S NADPH-dependent FMN reductase LEHHPAIP_01408 557436.Lreu_1553 2.7e-171 607.8 Lactobacillaceae mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02385 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family LEHHPAIP_01409 349123.Lreu23DRAFT_4483 1.4e-178 632.1 Lactobacillaceae hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKF@1239,3F4VU@33958,4HAYG@91061,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX LEHHPAIP_01410 349123.Lreu23DRAFT_4484 1.4e-229 802.0 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system LEHHPAIP_01411 557436.Lreu_1556 1e-77 296.2 Lactobacillaceae Bacteria 1U697@1239,3F7CB@33958,4IG0C@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase LEHHPAIP_01412 349123.Lreu23DRAFT_4489 7.7e-115 419.9 Lactobacillaceae ktrA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ9H@1239,3F5G0@33958,4HBPH@91061,COG0569@1,COG0569@2 NA|NA|NA P domain protein LEHHPAIP_01413 557436.Lreu_1558 4.5e-239 833.6 Lactobacillaceae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,3F5BE@33958,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P Potassium uptake protein LEHHPAIP_01414 557436.Lreu_1559 0.0 1226.5 Lactobacillaceae mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen LEHHPAIP_01415 349123.Lreu23DRAFT_4492 1.7e-139 501.9 Lactobacillaceae nfrA 1.5.1.38,1.5.1.39 ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,3F4IY@33958,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase LEHHPAIP_01416 557436.Lreu_1561 1e-223 782.3 Lactobacillaceae Bacteria 1VTKQ@1239,3FC1V@33958,4HTYV@91061,COG3405@1,COG3405@2 NA|NA|NA G Glycosyl hydrolases family 8 LEHHPAIP_01417 557436.Lreu_1562 8.5e-243 845.9 Lactobacillaceae ydaM Bacteria 1TR2P@1239,3F3RY@33958,4HAQN@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase LEHHPAIP_01418 557436.Lreu_1563 3.3e-142 511.1 Lactobacillaceae Bacteria 1VR8Q@1239,2F08C@1,33TBR@2,3F6XD@33958,4HTKM@91061 NA|NA|NA LEHHPAIP_01419 349123.Lreu23DRAFT_4497 6.6e-125 453.4 Lactobacillaceae phoU ko:K02039 ko00000 Bacteria 1URN3@1239,3F46W@33958,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake LEHHPAIP_01420 349123.Lreu23DRAFT_4498 3.1e-136 491.1 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system LEHHPAIP_01421 557436.Lreu_1566 2.6e-155 554.7 Lactobacillaceae pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3F412@33958,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease protein PstA LEHHPAIP_01422 349123.Lreu23DRAFT_4500 1.9e-153 548.5 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane LEHHPAIP_01423 557436.Lreu_1568 1.1e-158 565.8 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate LEHHPAIP_01424 557436.Lreu_1569 3.6e-131 474.2 Lactobacillaceae Bacteria 1TPWS@1239,3F61A@33958,4H9KP@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C-terminal domain protein LEHHPAIP_01425 557436.Lreu_0350 9.7e-20 102.1 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase LEHHPAIP_01426 557436.Lreu_0350 1.3e-145 522.3 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase LEHHPAIP_01427 557436.Lreu_0350 3.2e-39 167.9 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase LEHHPAIP_01428 349123.Lreu23DRAFT_3740 2.2e-16 92.0 Lactobacillaceae Bacteria 1U6N9@1239,29PIU@1,30AGZ@2,3F86N@33958,4IGF9@91061 NA|NA|NA K Transcriptional regulator, HxlR family LEHHPAIP_01429 349123.Lreu23DRAFT_4519 3.9e-187 660.6 Lactobacillaceae Bacteria 1VQC4@1239,2EPCR@1,33GZE@2,3F8F8@33958,4HSDU@91061 NA|NA|NA LEHHPAIP_01430 557436.Lreu_1574 1.2e-97 362.5 Lactobacillaceae 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1VEW7@1239,3F5HK@33958,4HPE4@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase LEHHPAIP_01431 557436.Lreu_1575 4e-83 313.9 Lactobacillaceae manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,3F40I@33958,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase LEHHPAIP_01432 557436.Lreu_1578 8.2e-70 269.6 Lactobacillaceae 1.1.1.90 ko:K00055,ko:K06898 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8E@1239,3F3QP@33958,4HAH9@91061,COG1062@1,COG1062@2 NA|NA|NA C Zn-dependent alcohol dehydrogenases, class III LEHHPAIP_01433 557436.Lreu_1579 1.3e-53 215.7 Lactobacillaceae ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1V6SG@1239,3F74A@33958,4HIZN@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family LEHHPAIP_01434 557436.Lreu_1580 3.9e-182 644.0 Lactobacillaceae Bacteria 1U5CK@1239,2ACE2@1,311ZJ@2,3F5IZ@33958,4IF3R@91061 NA|NA|NA LEHHPAIP_01435 349123.Lreu23DRAFT_4525 4.2e-98 364.0 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F422@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase LEHHPAIP_01436 557436.Lreu_1582 1.7e-183 648.7 Lactobacillaceae ko:K07035 ko00000 Bacteria 1TS5F@1239,3F4FE@33958,4HC7U@91061,COG3641@1,COG3641@2 NA|NA|NA S Phosphotransferase system, EIIC LEHHPAIP_01437 349123.Lreu23DRAFT_3280 3e-27 127.1 Lactobacillaceae ko:K07491 ko00000 Bacteria 1TSQ0@1239,3F6VR@33958,4HGEM@91061,COG1943@1,COG1943@2 NA|NA|NA L PFAM transposase IS200-family protein LEHHPAIP_01439 349123.Lreu23DRAFT_3073 6.3e-37 159.8 Lactobacillaceae ltrA_1 Bacteria 1TP9A@1239,3F4TJ@33958,4H9NW@91061,COG3344@1,COG3344@2 NA|NA|NA L PFAM RNA-directed DNA polymerase (Reverse transcriptase) LEHHPAIP_01440 349123.Lreu23DRAFT_4947 6.5e-251 872.8 Lactobacillaceae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,3F3M6@33958,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) LEHHPAIP_01441 349123.Lreu23DRAFT_4948 2e-264 917.9 Lactobacillaceae glnP ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQUG@1239,3F4HA@33958,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter LEHHPAIP_01442 349123.Lreu23DRAFT_4949 5.5e-138 496.9 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10038 ko02010,map02010 M00227,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.2 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein LEHHPAIP_01443 557436.Lreu_0100 1.4e-219 768.8 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease LEHHPAIP_01444 349123.Lreu23DRAFT_4952 1.3e-218 765.4 Lactobacillaceae nupG GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015212,GO:0015213,GO:0015214,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015506,GO:0015672,GO:0015858,GO:0015861,GO:0015862,GO:0015864,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072531,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1901505,GO:1901642,GO:1902600 ko:K03317,ko:K16323 ko00000,ko02000 2.A.41,2.A.41.1 Bacteria 1TRSK@1239,3FB6J@33958,4HBRZ@91061,COG1972@1,COG1972@2 NA|NA|NA F Nucleoside transporter LEHHPAIP_01445 557436.Lreu_0102 3.3e-169 600.9 Lactobacillaceae rihC 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSSS@1239,3F4T0@33958,4HB17@91061,COG1957@1,COG1957@2 NA|NA|NA F Nucleoside LEHHPAIP_01446 349123.Lreu23DRAFT_4954 2.7e-160 571.2 Lactobacillaceae fadB4 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 1TPJS@1239,3F4SY@33958,4HA59@91061,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase LEHHPAIP_01447 349123.Lreu23DRAFT_4955 9.2e-122 443.0 Lactobacillaceae rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1TPBT@1239,3F3ZX@33958,4HAAZ@91061,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA LEHHPAIP_01448 349123.Lreu23DRAFT_4956 1.8e-144 518.8 Lactobacillaceae noc ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TP0I@1239,3F4RU@33958,4HAC6@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family LEHHPAIP_01449 557436.Lreu_0106 3.6e-140 504.2 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3F4AE@33958,4HAYM@91061,COG1192@1,COG1192@2 NA|NA|NA D Sporulation initiation inhibitor LEHHPAIP_01450 349123.Lreu23DRAFT_4958 1.9e-153 548.5 Lactobacillaceae spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TQ2B@1239,3F47R@33958,4H9TB@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family LEHHPAIP_01451 349123.Lreu23DRAFT_4959 1.2e-31 141.7 Lactobacillaceae yyzM Bacteria 1VEQ7@1239,3F823@33958,4HNHU@91061,COG4481@1,COG4481@2 NA|NA|NA S Bacterial protein of unknown function (DUF951) LEHHPAIP_01452 557436.Lreu_0109 2e-200 704.9 Lactobacillaceae ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1TPRK@1239,3F3TK@33958,4H9SQ@91061,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner LEHHPAIP_01453 557436.Lreu_0110 3.1e-136 491.1 Lactobacillaceae XK27_01040 Bacteria 1VF5N@1239,3FCFF@33958,4HJMB@91061,COG4858@1,COG4858@2 NA|NA|NA S Protein of unknown function (DUF1129) LEHHPAIP_01454 349123.Lreu23DRAFT_4962 3.4e-118 431.0 Lactobacillaceae deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4,5.4.2.8 ko:K01619,ko:K01840 ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130 M00114 R01066,R01818 RC00408,RC00436,RC00437 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAJ@1239,3F4M3@33958,4HAAJ@91061,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate LEHHPAIP_01455 349123.Lreu23DRAFT_4963 4.5e-235 820.1 Lactobacillaceae deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 R01057,R02749 RC00408 ko00000,ko00001,ko01000 Bacteria 1TP70@1239,3F3Y4@33958,4H9RU@91061,COG1015@1,COG1015@2 NA|NA|NA G Phosphotransfer between the C1 and C5 carbon atoms of pentose LEHHPAIP_01456 557436.Lreu_0113 2.1e-233 814.7 Lactobacillaceae pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 iHN637.CLJU_RS08925 Bacteria 1TPCH@1239,3F45P@33958,4H9NP@91061,COG0213@1,COG0213@2 NA|NA|NA F pyrimidine-nucleoside phosphorylase LEHHPAIP_01457 349123.Lreu23DRAFT_4965 1.1e-130 472.6 Lactobacillaceae deoD GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1,2.4.2.28 ko:K00772,ko:K03784 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468 Bacteria 1TQPG@1239,3F4K1@33958,4HADM@91061,COG0813@1,COG0813@2 NA|NA|NA F Purine nucleoside phosphorylase LEHHPAIP_01458 557436.Lreu_0115 1.2e-169 602.4 Lactobacillaceae deoR GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05346 ko00000,ko03000 Bacteria 1TPUB@1239,3F4PP@33958,4HCAR@91061,COG2390@1,COG2390@2 NA|NA|NA K sugar-binding domain protein LEHHPAIP_01459 557436.Lreu_0116 4.1e-209 733.8 Lactobacillaceae guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1TNZ1@1239,3F3XN@33958,4H9V3@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides LEHHPAIP_01460 349123.Lreu23DRAFT_4968 3.8e-125 454.1 Lactobacillaceae Bacteria 1TP9M@1239,3F3Y0@33958,4HB3T@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator LEHHPAIP_01461 349123.Lreu23DRAFT_4969 2.4e-201 708.0 Lactobacillaceae hpk31 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPB6@1239,3F479@33958,4HARU@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase LEHHPAIP_01462 349123.Lreu23DRAFT_4970 2.3e-138 498.4 Lactobacillaceae azlC Bacteria 1TP8P@1239,3FB4H@33958,4HN4R@91061,COG1296@1,COG1296@2 NA|NA|NA E AzlC protein LEHHPAIP_01463 557436.Lreu_0120 1.6e-52 211.8 Lactobacillaceae azlD Bacteria 1UF1S@1239,3F7GD@33958,4HQ7J@91061,COG4392@1,COG4392@2 NA|NA|NA S branched-chain amino acid LEHHPAIP_01464 349123.Lreu23DRAFT_4972 6.6e-124 450.3 Lactobacillaceae ko:K09681 ko00000,ko03000 Bacteria 1TQ6Y@1239,3F4CY@33958,4HWQQ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain LEHHPAIP_01465 557436.Lreu_0123 5e-173 613.6 Lactobacillaceae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1TQ96@1239,3F4BQ@33958,4H9M6@91061,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family LEHHPAIP_01466 557436.Lreu_0124 2.1e-246 857.8 Lactobacillaceae pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,3F3S3@33958,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily LEHHPAIP_01467 349123.Lreu23DRAFT_4975 3.3e-172 610.9 Lactobacillaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 1TPFV@1239,3F4PJ@33958,4HA5H@91061,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily LEHHPAIP_01468 349123.Lreu23DRAFT_4976 6e-129 466.8 Lactobacillaceae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1TPPH@1239,3F47Y@33958,4HAJ2@91061,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) LEHHPAIP_01469 557436.Lreu_0127 9.6e-115 419.5 Lactobacillaceae pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1V1BZ@1239,3F487@33958,4HFV7@91061,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) LEHHPAIP_01470 557436.Lreu_0128 1.1e-113 416.0 Lactobacillaceae thiE 2.5.1.3,2.7.6.2,5.4.2.6 ko:K00788,ko:K00949,ko:K01838,ko:K07025 ko00500,ko00730,ko01100,map00500,map00730,map01100 M00127 R00619,R02728,R03223,R10712,R11310 RC00002,RC00017,RC00224,RC00408,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7JX@1239,3F9UF@33958,4IHH2@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase LEHHPAIP_01471 944562.HMPREF9102_1861 7.9e-96 356.7 Lactobacillaceae ribA 3.5.4.25,4.1.99.12 ko:K01497,ko:K14652 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 Bacteria 1U24A@1239,3F4KE@33958,4IBMV@91061,COG0108@1,COG0108@2 NA|NA|NA H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate LEHHPAIP_01472 557436.Lreu_0129 1.8e-228 798.1 Lactobacillaceae cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1TSG4@1239,3F3PA@33958,4HDKI@91061,COG2230@1,COG2230@2 NA|NA|NA M cyclopropane-fatty-acyl-phospholipid synthase LEHHPAIP_01473 349123.Lreu23DRAFT_4980 6.6e-174 616.7 Lactobacillaceae Bacteria 1TSBK@1239,3F46E@33958,4HBYJ@91061,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter LEHHPAIP_01474 349123.Lreu23DRAFT_4981 0.0 1097.4 Lactobacillaceae fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family LEHHPAIP_01475 349123.Lreu23DRAFT_4982 0.0 1102.0 Lactobacillaceae alsS 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQE8@1239,3FCE6@33958,4HAV1@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family LEHHPAIP_01476 349123.Lreu23DRAFT_4983 4.5e-129 467.2 Lactobacillaceae budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 1V4AH@1239,3F41S@33958,4HJ98@91061,COG3527@1,COG3527@2 NA|NA|NA H Belongs to the alpha-acetolactate decarboxylase family LEHHPAIP_01477 1114972.AUAW01000021_gene2173 2.7e-24 118.2 Lactobacillaceae Bacteria 1UZG6@1239,3F85W@33958,4HCQS@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein LEHHPAIP_01478 272621.LBA1214 3.4e-187 661.4 Lactobacillaceae thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 1TPR0@1239,3F3UF@33958,4H9R7@91061,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase LEHHPAIP_01479 575594.ACOH01000011_gene417 5.8e-172 610.5 Lactobacillaceae hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1TQ2H@1239,3F5BM@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase LEHHPAIP_01480 575594.ACOH01000011_gene416 8.1e-101 373.6 Lactobacillaceae thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 1TRWS@1239,3F44T@33958,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate LEHHPAIP_01481 349123.Lreu23DRAFT_4984 1.1e-83 315.8 Lactobacillaceae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,3F6P0@33958,4HFR7@91061,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) LEHHPAIP_01482 349123.Lreu23DRAFT_4985 1.5e-214 751.9 Lactobacillaceae purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) LEHHPAIP_01483 349123.Lreu23DRAFT_4986 8.9e-253 879.0 Lactobacillaceae purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095 Bacteria 1TPMM@1239,3F48P@33958,4HACW@91061,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily LEHHPAIP_01484 557436.Lreu_0137 1.4e-130 472.2 Lactobacillaceae purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 1TP11@1239,3F44Z@33958,4H9U8@91061,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family LEHHPAIP_01485 557436.Lreu_0138 1.8e-37 161.4 Lactobacillaceae purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1VEH1@1239,3F81F@33958,4HP0E@91061,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL LEHHPAIP_01486 557436.Lreu_0139 3.1e-127 461.1 Lactobacillaceae purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1B@1239,3F48D@33958,4HAKZ@91061,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL LEHHPAIP_01487 557436.Lreu_0140 0.0 1478.4 Lactobacillaceae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAS@1239,3F4IQ@33958,4HB3N@91061,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL LEHHPAIP_01488 557436.Lreu_0141 2e-277 961.1 Lactobacillaceae purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,3F3U7@33958,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine LEHHPAIP_01489 557436.Lreu_0142 6.2e-196 689.9 Lactobacillaceae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1TP9J@1239,3F4RT@33958,4HABW@91061,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase LEHHPAIP_01490 349123.Lreu23DRAFT_4993 8e-105 386.3 Lactobacillaceae purN 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3RJ@1239,3F3UN@33958,4HGY5@91061,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate LEHHPAIP_01491 557436.Lreu_0144 1.5e-294 1018.1 Lactobacillaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,3F4FD@33958,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH LEHHPAIP_01492 557436.Lreu_0145 2.8e-243 847.4 Lactobacillaceae purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 1UHN9@1239,3F4Z8@33958,4HA70@91061,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family LEHHPAIP_01493 349123.Lreu23DRAFT_4996 1e-130 472.6 Lactobacillaceae gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQFP@1239,3F3SK@33958,4HAW7@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate LEHHPAIP_01494 557436.Lreu_0147 1.8e-166 592.0 Lactobacillaceae Bacteria 1U59P@1239,29NNF@1,309KD@2,3F5AE@33958,4IF13@91061 NA|NA|NA LEHHPAIP_01495 349123.Lreu23DRAFT_4998 5.4e-239 833.2 Lactobacillaceae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 1TPGN@1239,3F48J@33958,4H9YV@91061,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) LEHHPAIP_01496 557436.Lreu_0275 6.4e-90 336.7 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family LEHHPAIP_01497 557436.Lreu_0275 5.3e-40 169.9 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family LEHHPAIP_01500 557436.Lreu_0277 1.3e-263 915.2 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter LEHHPAIP_01501 557436.Lreu_0278 2.7e-149 534.6 Lactobacillaceae yjjH Bacteria 1VHY9@1239,3F3SW@33958,4HPAR@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase LEHHPAIP_01504 349123.Lreu23DRAFT_3320 1e-111 409.5 Lactobacillaceae Bacteria 1U5V7@1239,29NYS@1,309WV@2,3F6J8@33958,4IFIU@91061 NA|NA|NA LEHHPAIP_01505 349123.Lreu23DRAFT_3322 3.2e-248 864.0 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_01506 557436.Lreu_0281 1.6e-299 1034.6 Lactobacillaceae aspT ko:K07085 ko00000 2.A.81 Bacteria 1UGE4@1239,3F5RV@33958,4HTZ2@91061,COG2985@1,COG2985@2 NA|NA|NA P Predicted Permease Membrane Region LEHHPAIP_01507 349123.Lreu23DRAFT_3324 2.4e-130 471.5 Lactobacillaceae racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1V28U@1239,3FBJU@33958,4IQX8@91061,COG1794@1,COG1794@2 NA|NA|NA M Belongs to the aspartate glutamate racemases family LEHHPAIP_01508 349123.Lreu23DRAFT_3325 1.8e-127 461.8 Lactobacillaceae gntR1 ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1UYBW@1239,3F4D0@33958,4HDDG@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein LEHHPAIP_01509 557436.Lreu_0284 6.9e-286 989.2 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP LEHHPAIP_01510 557436.Lreu_0285 4.4e-152 543.9 Lactobacillaceae nadE GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 1TQ38@1239,3F43Z@33958,4HA2R@91061,COG0171@1,COG0171@2 NA|NA|NA F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source LEHHPAIP_01511 557436.Lreu_0286 0.0 1411.4 Lactobacillaceae yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K06959 ko00000 Bacteria 1TPFE@1239,3F415@33958,4HAGY@91061,COG2183@1,COG2183@2 NA|NA|NA K Tex-like protein N-terminal domain protein LEHHPAIP_01512 557436.Lreu_0287 1.5e-82 312.0 Lactobacillaceae ydcK ko:K03095 ko00000 Bacteria 1V6NU@1239,3F703@33958,4HIHY@91061,COG3091@1,COG3091@2 NA|NA|NA S Belongs to the SprT family LEHHPAIP_01514 557436.Lreu_0288 0.0 1305.4 Lactobacillaceae lacL 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1TPDC@1239,3F4EI@33958,4HANW@91061,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family LEHHPAIP_01515 557436.Lreu_0289 2.2e-184 651.4 Lactobacillaceae lacM 3.2.1.23,3.2.1.35,3.2.1.51,3.2.1.97 ko:K01190,ko:K01197,ko:K01206,ko:K17624 ko00052,ko00511,ko00531,ko00600,ko01100,map00052,map00511,map00531,map00600,map01100 M00076,M00077 R01105,R01678,R03355,R04783,R06114,R07824,R07825,R10905 RC00049,RC00452 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko04147 GH101,GH29 Bacteria 1TRVA@1239,3F51Z@33958,4HFMH@91061,COG3250@1,COG3250@2 NA|NA|NA G beta-galactosidase LEHHPAIP_01516 349123.Lreu23DRAFT_3333 0.0 1131.3 Lactobacillaceae Bacteria 1UZCF@1239,3F48H@33958,4HDPY@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO LEHHPAIP_01517 349123.Lreu23DRAFT_3334 1e-133 482.6 Lactobacillaceae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V2UT@1239,3FB95@33958,4HGRK@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate LEHHPAIP_01518 349123.Lreu23DRAFT_3335 3.8e-167 594.0 Lactobacillaceae Bacteria 1VSAN@1239,3F60S@33958,4HEXJ@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold LEHHPAIP_01519 557436.Lreu_0293 2.9e-215 754.2 Lactobacillaceae metC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine LEHHPAIP_01520 557436.Lreu_0294 1.1e-119 436.0 Lactobacillaceae tcyB GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0033229,GO:0034220,GO:0042883,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098655,GO:0098656,GO:1901682,GO:1902475,GO:1903712,GO:1903825,GO:1905039 ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 iYO844.BSU03600 Bacteria 1TPQ8@1239,3F4QR@33958,4H9N1@91061,COG0765@1,COG0765@2 NA|NA|NA E ABC transporter LEHHPAIP_01521 349123.Lreu23DRAFT_3338 2.2e-134 485.0 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10010 ko02010,map02010 M00234,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14 Bacteria 1TNYD@1239,3F4YF@33958,4HUHS@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein LEHHPAIP_01522 557436.Lreu_0296 4e-139 500.7 Lactobacillaceae tcyA ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 Bacteria 1TR13@1239,3F4MH@33958,4HBRP@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family LEHHPAIP_01523 557436.Lreu_0297 1.9e-266 924.5 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F49B@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family LEHHPAIP_01524 349123.Lreu23DRAFT_3341 2.2e-125 454.9 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,3F43N@33958,4HFQ7@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate LEHHPAIP_01525 349123.Lreu23DRAFT_3342 3.8e-50 203.8 Lactobacillaceae HA62_12640 ko:K06975 ko00000 Bacteria 1VEEX@1239,3F80F@33958,4HNR2@91061,COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase LEHHPAIP_01526 557436.Lreu_0300 3.6e-99 367.5 Lactobacillaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V6HX@1239,3F65D@33958,4HIZ3@91061,COG0756@1,COG0756@2 NA|NA|NA F dUTP diphosphatase LEHHPAIP_01527 557436.Lreu_0301 7.8e-255 885.9 Lactobacillaceae radA ko:K04485 ko00000,ko03400 Bacteria 1TQ7Y@1239,3F3W8@33958,4H9YC@91061,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function LEHHPAIP_01528 349123.Lreu23DRAFT_3345 1.1e-204 719.2 Lactobacillaceae yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TP0P@1239,3F46T@33958,4H9NQ@91061,COG4956@1,COG4956@2 NA|NA|NA S domain protein LEHHPAIP_01529 557436.Lreu_0303 1.3e-273 948.3 Lactobacillaceae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1TP9D@1239,3F4K7@33958,4HA6D@91061,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family LEHHPAIP_01530 349123.Lreu23DRAFT_3347 4.7e-70 270.4 Lactobacillaceae mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K11145 ko00000,ko01000,ko03009 Bacteria 1VA5V@1239,3F6HS@33958,4HIM3@91061,COG1939@1,COG1939@2 NA|NA|NA J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) LEHHPAIP_01531 557436.Lreu_0305 4.7e-137 493.8 Lactobacillaceae rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K12952 ko00000,ko01000,ko03009,ko03016 3.A.3.23 Bacteria 1TP9G@1239,3F3TD@33958,4HBBI@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family LEHHPAIP_01532 349123.Lreu23DRAFT_3349 1.4e-21 107.8 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VFTQ@1239,3F83F@33958,4HR5Q@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family LEHHPAIP_01533 349123.Lreu23DRAFT_3350 1.4e-15 88.2 Lactobacillaceae secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VK48@1239,3F86Y@33958,4HR1W@91061,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation LEHHPAIP_01534 349123.Lreu23DRAFT_3351 3.4e-97 360.9 Lactobacillaceae nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1TR3P@1239,3F55W@33958,4HAJA@91061,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination LEHHPAIP_01535 349123.Lreu23DRAFT_3352 3.7e-70 270.8 Lactobacillaceae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1BS@1239,3F64I@33958,4HFQ0@91061,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors LEHHPAIP_01536 349123.Lreu23DRAFT_3353 3e-122 444.5 Lactobacillaceae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPTS@1239,3F3VQ@33958,4HAK4@91061,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release LEHHPAIP_01537 557436.Lreu_0310 2.8e-224 784.3 Lactobacillaceae aadAT ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 R01939 RC00006 ko00000,ko00001,ko01000 Bacteria 1TPS5@1239,3F4AH@33958,4H9M3@91061,COG1167@1,COG1167@2 NA|NA|NA EK Aminotransferase, class I LEHHPAIP_01539 557436.Lreu_0311 1.8e-32 144.8 Lactobacillaceae Bacteria 1VX75@1239,3F5WJ@33958,4HH0B@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family group 2 LEHHPAIP_01540 557436.Lreu_0311 6.3e-154 550.1 Lactobacillaceae Bacteria 1VX75@1239,3F5WJ@33958,4HH0B@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family group 2 LEHHPAIP_01541 557436.Lreu_0312 4e-209 733.8 Lactobacillaceae mnaA 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1TQZT@1239,3F3KQ@33958,4HBI3@91061,COG0381@1,COG0381@2 NA|NA|NA G Belongs to the UDP-N-acetylglucosamine 2-epimerase family LEHHPAIP_01542 349123.Lreu23DRAFT_3359 3.8e-82 310.8 Lactobacillaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JJ@1239,3F4S4@33958,4HH0N@91061,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors LEHHPAIP_01543 349123.Lreu23DRAFT_3360 3.2e-54 217.6 Lactobacillaceae rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6EI@1239,3F6YA@33958,4HIGQ@91061,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation LEHHPAIP_01544 557436.Lreu_0315 4.8e-34 150.2 Lactobacillaceae Bacteria 1U6JA@1239,29PGB@1,30AEG@2,3F80W@33958,4IGBU@91061 NA|NA|NA LEHHPAIP_01545 349123.Lreu23DRAFT_3363 3.2e-38 164.5 Lactobacillaceae mscL GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1VA14@1239,3F6YZ@33958,4HKIA@91061,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell LEHHPAIP_01546 557436.Lreu_0318 2.4e-56 224.6 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VIVQ@1239,3FBMB@33958,4IR4R@91061,COG1695@1,COG1695@2 NA|NA|NA K transcriptional regulator PadR family LEHHPAIP_01547 349123.Lreu23DRAFT_3365 8.7e-81 306.6 Lactobacillaceae XK27_06920 Bacteria 1VBG6@1239,3F6I7@33958,4HSRQ@91061,COG4709@1,COG4709@2 NA|NA|NA S Protein of unknown function (DUF1700) LEHHPAIP_01548 557436.Lreu_0320 3.2e-133 481.1 Lactobacillaceae Bacteria 1VKFR@1239,3F74T@33958,4HRQ4@91061,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin LEHHPAIP_01549 557436.Lreu_0321 0.0 1713.0 Lactobacillaceae adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 Bacteria 1TPB4@1239,3F3RN@33958,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family LEHHPAIP_01550 349123.Lreu23DRAFT_3368 2.2e-198 698.0 Lactobacillaceae nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,3F3P1@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides LEHHPAIP_01551 557436.Lreu_0323 0.0 1446.8 Lactobacillaceae nrdE 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides LEHHPAIP_01552 349123.Lreu23DRAFT_3370 3.4e-35 153.7 Lactobacillaceae nrdH GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009 ko:K06191 ko00000 Bacteria 1VE2N@1239,3FBRA@33958,4HSRX@91061,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin LEHHPAIP_01553 557436.Lreu_0325 5.2e-87 327.0 Lactobacillaceae tadA 3.5.4.33 ko:K11991 R10223 RC00477 ko00000,ko01000,ko03016 Bacteria 1V3HZ@1239,3F6IS@33958,4HH7S@91061,COG0590@1,COG0590@2 NA|NA|NA F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) LEHHPAIP_01554 557436.Lreu_0326 7.6e-290 1002.7 Lactobacillaceae dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPS9@1239,3F3P2@33958,4HAUE@91061,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity LEHHPAIP_01555 349123.Lreu23DRAFT_3373 7e-47 193.0 Lactobacillaceae yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,3F7F3@33958,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection LEHHPAIP_01556 349123.Lreu23DRAFT_3374 6.3e-108 396.7 Lactobacillaceae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TR87@1239,3F4JQ@33958,4HAZR@91061,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO LEHHPAIP_01557 557436.Lreu_0329 1.1e-37 162.2 Lactobacillaceae Bacteria 1U6F9@1239,2DKQF@1,30ABA@2,3F7S7@33958,4IG70@91061 NA|NA|NA S Protein of unknown function (DUF2508) LEHHPAIP_01558 349123.Lreu23DRAFT_3376 7.6e-112 409.8 Lactobacillaceae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02535 Bacteria 1V1HE@1239,3F4JR@33958,4HGWR@91061,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis LEHHPAIP_01559 349123.Lreu23DRAFT_3377 2.9e-51 207.6 Lactobacillaceae yaaQ Bacteria 1V6NI@1239,3F6VW@33958,4HIHA@91061,COG3870@1,COG3870@2 NA|NA|NA S Cyclic-di-AMP receptor LEHHPAIP_01560 557436.Lreu_0332 1.7e-182 645.2 Lactobacillaceae holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRVS@1239,3F50D@33958,4HA3T@91061,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III LEHHPAIP_01561 349123.Lreu23DRAFT_3379 3.1e-43 181.0 Lactobacillaceae yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1VA1F@1239,3F864@33958,4HKND@91061,COG4467@1,COG4467@2 NA|NA|NA L Involved in initiation control of chromosome replication LEHHPAIP_01562 557436.Lreu_0334 7.5e-155 553.1 Lactobacillaceae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1TP6U@1239,3F4AI@33958,4HAH8@91061,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA LEHHPAIP_01563 557436.Lreu_0335 8.4e-134 483.0 Lactobacillaceae fat 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 Bacteria 1V3RB@1239,3F41B@33958,4HHJ4@91061,COG3884@1,COG3884@2 NA|NA|NA I Acyl-ACP thioesterase LEHHPAIP_01564 557436.Lreu_0336 9.7e-283 978.8 Lactobacillaceae ppx3 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1VT8Q@1239,3F49N@33958,4HB84@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase LEHHPAIP_01565 557436.Lreu_0337 0.0 1480.7 Lactobacillaceae ppk GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iJN746.PP_5217 Bacteria 1TNZM@1239,3F3PE@33958,4HA88@91061,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) LEHHPAIP_01566 349123.Lreu23DRAFT_3384 6.4e-171 606.7 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase LEHHPAIP_01567 349123.Lreu23DRAFT_3385 6.8e-192 676.4 Lactobacillaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,3F3YF@33958,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family LEHHPAIP_01569 557436.Lreu_0150 3.1e-62 244.2 Lactobacillaceae XK27_01125 ko:K07484 ko00000 Bacteria 1VAJD@1239,3F7E1@33958,4HKCG@91061,COG3436@1,COG3436@2 NA|NA|NA L PFAM IS66 Orf2 family protein LEHHPAIP_01570 557436.Lreu_0151 9.9e-69 266.2 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family LEHHPAIP_01571 557436.Lreu_1046 4.2e-109 401.0 Lactobacillaceae Bacteria 1TPPI@1239,3FB7D@33958,4HAKP@91061,COG1484@1,COG1484@2 NA|NA|NA L Bacterial dnaA protein LEHHPAIP_01572 557436.Lreu_1047 2.6e-137 495.4 Lactobacillaceae Bacteria 1TR5X@1239,3F57W@33958,4HBD9@91061,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain LEHHPAIP_01573 557436.Lreu_0151 2.8e-188 664.5 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family LEHHPAIP_01574 557436.Lreu_0150 3.1e-62 244.2 Lactobacillaceae XK27_01125 ko:K07484 ko00000 Bacteria 1VAJD@1239,3F7E1@33958,4HKCG@91061,COG3436@1,COG3436@2 NA|NA|NA L PFAM IS66 Orf2 family protein LEHHPAIP_01576 349123.Lreu23DRAFT_3632 5e-182 643.7 Lactobacillaceae pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3J@1239,3F3RC@33958,4HBHB@91061,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller LEHHPAIP_01577 557436.Lreu_0579 1.4e-158 565.5 Lactobacillaceae rrmA 2.1.1.187 ko:K00563,ko:K10947 R07233 RC00003 ko00000,ko01000,ko03000,ko03009 Bacteria 1V1WE@1239,3F4U3@33958,4HGQ9@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase LEHHPAIP_01578 349123.Lreu23DRAFT_3634 2.3e-95 354.8 Lactobacillaceae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1V3GW@1239,3F42Y@33958,4HFNY@91061,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily LEHHPAIP_01579 557436.Lreu_0581 0.0 1422.5 Lactobacillaceae ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F3JZ@33958,4H9WA@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family LEHHPAIP_01580 349123.Lreu23DRAFT_3636 1.2e-10 71.2 Lactobacillaceae Bacteria 1U73D@1239,29PVH@1,30ATR@2,3F8XG@33958,4IGXZ@91061 NA|NA|NA S Protein of unknown function (DUF4044) LEHHPAIP_01581 349123.Lreu23DRAFT_3637 1.7e-57 228.4 Lactobacillaceae Bacteria 1U6JI@1239,29PGG@1,30AEM@2,3F81C@33958,4IGC0@91061 NA|NA|NA LEHHPAIP_01582 349123.Lreu23DRAFT_3638 3.1e-77 294.3 Lactobacillaceae mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1V3JD@1239,3F6K3@33958,4HH23@91061,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family LEHHPAIP_01583 557436.Lreu_0585 8.8e-173 612.8 Lactobacillaceae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1TNZV@1239,3F3MF@33958,4H9U2@91061,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA LEHHPAIP_01584 349123.Lreu23DRAFT_3640 2.9e-55 221.1 Lactobacillaceae ftsL Bacteria 1VCE5@1239,3F6KG@33958,4HM4W@91061,COG4839@1,COG4839@2 NA|NA|NA D Cell division protein FtsL LEHHPAIP_01585 557436.Lreu_0587 0.0 1397.1 Lactobacillaceae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1TP93@1239,3F47N@33958,4H9VQ@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein LEHHPAIP_01586 349123.Lreu23DRAFT_3642 4.4e-180 637.1 Lactobacillaceae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1TP8W@1239,3F3YP@33958,4H9TP@91061,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan LEHHPAIP_01587 557436.Lreu_0589 4.2e-261 906.7 Lactobacillaceae murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQ3P@1239,3F49W@33958,4HA5P@91061,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) LEHHPAIP_01588 557436.Lreu_0590 1.6e-202 711.8 Lactobacillaceae murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1TQFT@1239,3F4FW@33958,4HBAQ@91061,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) LEHHPAIP_01589 557436.Lreu_0591 2.1e-141 508.4 Lactobacillaceae divIB ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1V6V5@1239,3F406@33958,4HDFD@91061,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex LEHHPAIP_01590 349123.Lreu23DRAFT_3646 2.5e-253 880.9 Lactobacillaceae ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TP1Z@1239,3F413@33958,4H9NF@91061,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring LEHHPAIP_01591 349123.Lreu23DRAFT_3647 3.5e-222 777.3 Lactobacillaceae ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1TP6W@1239,3F4V1@33958,4H9WZ@91061,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity LEHHPAIP_01592 349123.Lreu23DRAFT_3648 2.1e-70 271.6 Lactobacillaceae sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 1VER3@1239,3F7MQ@33958,4HKIC@91061,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA LEHHPAIP_01593 349123.Lreu23DRAFT_3649 3.2e-40 170.6 Lactobacillaceae yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1VEKA@1239,3F843@33958,4HNJR@91061,COG0762@1,COG0762@2 NA|NA|NA S YGGT family LEHHPAIP_01594 349123.Lreu23DRAFT_3650 2.4e-144 518.1 Lactobacillaceae ylmH ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1U5V2@1239,3F48W@33958,4HD3F@91061,COG2302@1,COG2302@2 NA|NA|NA S S4 domain protein LEHHPAIP_01595 557436.Lreu_0597 1.3e-35 156.8 Lactobacillaceae divIVA ko:K04074 ko00000,ko03036 Bacteria 1V27M@1239,3F4IN@33958,4HG80@91061,COG3599@1,COG3599@2 NA|NA|NA D DivIVA domain protein LEHHPAIP_01596 557436.Lreu_0598 0.0 1938.7 Lactobacillaceae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1TPS7@1239,3F3X4@33958,4HAWB@91061,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) LEHHPAIP_01597 349123.Lreu23DRAFT_3653 4.2e-32 143.3 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1W688@1239,3F81I@33958,4I1Y3@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein LEHHPAIP_01598 349123.Lreu23DRAFT_3654 1.1e-98 365.9 Lactobacillaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,3F53J@33958,4HII9@91061,COG0494@1,COG0494@2 NA|NA|NA L ADP-ribose pyrophosphatase LEHHPAIP_01600 557436.Lreu_0602 1.6e-123 448.7 Lactobacillaceae mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7WK@1239,3F4HE@33958,4HB8K@91061,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively LEHHPAIP_01601 557436.Lreu_0603 1.6e-216 758.4 Lactobacillaceae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F3RF@33958,4HA6H@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V LEHHPAIP_01602 557436.Lreu_0604 7.5e-58 229.6 Lactobacillaceae XK27_04120 Bacteria 1VDSF@1239,2DHWG@1,32U9W@2,3F7E3@33958,4HP9N@91061 NA|NA|NA S Putative amino acid metabolism LEHHPAIP_01603 557436.Lreu_0605 6.9e-225 786.2 Lactobacillaceae mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPIZ@1239,3F4N5@33958,4HBJ6@91061,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 LEHHPAIP_01604 557436.Lreu_0606 2.9e-122 444.5 Lactobacillaceae pgm6 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V6ES@1239,3F3U3@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase LEHHPAIP_01605 349123.Lreu23DRAFT_3661 4.9e-117 427.2 Lactobacillaceae Bacteria 1VFGR@1239,3F4MD@33958,4IBSH@91061,COG0457@1,COG0457@2 NA|NA|NA S Repeat protein LEHHPAIP_01606 349123.Lreu23DRAFT_3662 0.0 1577.0 Lactobacillaceae recD2 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,3F44X@33958,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity LEHHPAIP_01607 349123.Lreu23DRAFT_3663 6.9e-173 613.2 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3V8@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) LEHHPAIP_01608 349123.Lreu23DRAFT_3664 7.1e-181 639.8 Lactobacillaceae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMN@1239,3F4F7@33958,4HBH4@91061,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan LEHHPAIP_01609 557436.Lreu_0611 6.7e-259 899.4 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family LEHHPAIP_01610 557436.Lreu_0612 1.5e-244 851.7 Lactobacillaceae lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 1TPE9@1239,3F3VJ@33958,4H9XW@91061,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine LEHHPAIP_01611 349123.Lreu23DRAFT_3667 7e-74 283.9 Lactobacillaceae dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1TQUJ@1239,3F3U0@33958,4H9KY@91061,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate LEHHPAIP_01612 349123.Lreu23DRAFT_3668 1.1e-222 778.9 Lactobacillaceae hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3F419@33958,4H9SG@91061,COG1473@1,COG1473@2 NA|NA|NA E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate LEHHPAIP_01613 349123.Lreu23DRAFT_3669 2.9e-173 614.4 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) LEHHPAIP_01614 557436.Lreu_0616 4.3e-141 507.3 Lactobacillaceae dapB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490 Bacteria 1TR9D@1239,3F3MA@33958,4HA5X@91061,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate LEHHPAIP_01615 557436.Lreu_0617 7.7e-219 766.1 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase LEHHPAIP_01616 557436.Lreu_0618 1e-198 699.1 Lactobacillaceae asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC6@1239,3F4S9@33958,4HA9H@91061,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate LEHHPAIP_01617 525309.HMPREF0494_0681 8.5e-84 317.4 Lactobacillaceae ko:K02647 ko00000,ko03000 Bacteria 1TQWD@1239,3F4YQ@33958,4HB2H@91061,COG3835@1,COG3835@2 NA|NA|NA KT Putative sugar diacid recognition LEHHPAIP_01618 557436.Lreu_0621 4.2e-218 763.8 Lactobacillaceae ko:K03299 ko00000,ko02000 2.A.8 Bacteria 1TQ14@1239,3F57Q@33958,4HBI6@91061,COG2610@1,COG2610@2 NA|NA|NA EG GntP family permease LEHHPAIP_01619 557436.Lreu_0622 6e-208 729.9 Lactobacillaceae glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 1TPSI@1239,3F3V2@33958,4HA91@91061,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family LEHHPAIP_01620 557436.Lreu_0623 2.2e-57 228.0 Lactobacillaceae Bacteria 1U6U5@1239,29PNP@1,30AKW@2,3F8HP@33958,4IGMZ@91061 NA|NA|NA LEHHPAIP_01622 557436.Lreu_0625 1.7e-122 446.4 Lactobacillaceae mltD ko:K08307,ko:K12204,ko:K19224,ko:K21471 ko00000,ko01000,ko01002,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 CBM50 Bacteria 1VG0Z@1239,3F50V@33958,4HBE9@91061,COG0791@1,COG0791@2,COG1388@1,COG1388@2 NA|NA|NA M NlpC P60 family protein LEHHPAIP_01623 557436.Lreu_0626 5.7e-29 132.9 Lactobacillaceae Bacteria 1U6WX@1239,29PG6@1,30ANR@2,3F8N1@33958,4IGR3@91061 NA|NA|NA LEHHPAIP_01624 557436.Lreu_0627 1.9e-180 638.3 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQJH@1239,3FBKT@33958,4HJ8D@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic LEHHPAIP_01625 349123.Lreu23DRAFT_3679 9.8e-32 142.1 Lactobacillaceae ykzG Bacteria 1VEI7@1239,3F807@33958,4HNSK@91061,COG5503@1,COG5503@2 NA|NA|NA S Belongs to the UPF0356 family LEHHPAIP_01626 349123.Lreu23DRAFT_3680 4.8e-79 300.4 Lactobacillaceae Bacteria 1VQPI@1239,2C389@1,2ZQCN@2,3F79N@33958,4I0G9@91061 NA|NA|NA LEHHPAIP_01627 349123.Lreu23DRAFT_3681 1.4e-101 375.6 Lactobacillaceae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V70B@1239,3F3YH@33958,4HH0G@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions LEHHPAIP_01628 1297534.CAUJ01000005_gene97 5.3e-124 451.4 Bacilli repE Bacteria 1UBUD@1239,4HB0A@91061,COG1959@1,COG1959@2 NA|NA|NA K Primase C terminal 1 (PriCT-1) LEHHPAIP_01630 1035189.HMPREF9954_1860 1.8e-11 75.9 Streptococcus infantis Bacteria 1TWK7@1239,2DIZC@1,304ED@2,43GH6@68892,4I5DW@91061 NA|NA|NA S Thioredoxin LEHHPAIP_01632 1035189.HMPREF9954_1861 9.7e-07 60.8 Streptococcus infantis Bacteria 1TWJQ@1239,2DIZ5@1,304E3@2,43GFN@68892,4I5D8@91061 NA|NA|NA LEHHPAIP_01633 997830.HMPREF1124_0834 2.3e-27 129.8 Streptococcus infantis Bacteria 1W27X@1239,2DCHT@1,2ZE7E@2,43GGG@68892,4I25E@91061 NA|NA|NA LEHHPAIP_01638 1074451.CRL705_1887 9.5e-156 556.2 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair LEHHPAIP_01640 211110.gbs0382 9.3e-29 134.0 Bacilli ada 3.2.2.21 ko:K13529,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 1TR37@1239,4HHHQ@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA/RNA non-specific endonuclease LEHHPAIP_01642 997830.HMPREF1124_0825 6.7e-11 74.3 Streptococcus infantis Bacteria 1TWKB@1239,2BKU4@1,32FAD@2,43GHI@68892,4I5E1@91061 NA|NA|NA LEHHPAIP_01643 1161413.HMPREF1510_1730 3.4e-125 456.1 Bacilli ruvB 3.6.4.12 ko:K03551,ko:K07126 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V0DS@1239,4HENV@91061,COG2255@1,COG2255@2 NA|NA|NA L four-way junction helicase activity LEHHPAIP_01647 1121865.OMW_00624 1.9e-76 295.4 Firmicutes Bacteria 1VSR7@1239,2EYQW@1,33RY9@2 NA|NA|NA LEHHPAIP_01651 203123.OEOE_0093 1.8e-194 686.0 Leuconostocaceae traI 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 1TPJD@1239,4AYEZ@81850,4HAZV@91061,COG0550@1,COG0550@2 NA|NA|NA L C-terminal repeat of topoisomerase LEHHPAIP_01655 482234.SCAZ3_00280 3.9e-188 664.8 Bacilli clpB ko:K03694,ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Bacteria 1TPMU@1239,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family LEHHPAIP_01658 1403946.Q615_SPAC00114G0040 2.5e-16 94.4 Streptococcus anginosus group Bacteria 1TW0G@1239,2DIU0@1,3044E@2,42EHD@671232,4I4P6@91061 NA|NA|NA LEHHPAIP_01659 1123315.AUIP01000020_gene2240 4e-264 917.9 Bacilli ko:K03205 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1TPCF@1239,4H9ZN@91061,COG3505@1,COG3505@2 NA|NA|NA U COG3505 Type IV secretory pathway, VirD4 components LEHHPAIP_01660 883168.HMPREF9318_00143 2.7e-89 337.0 Bacteria Bacteria 2DF83@1,2ZQUZ@2 NA|NA|NA LEHHPAIP_01662 1423806.JCM15457_1771 3e-23 117.5 Lactobacillaceae Bacteria 1W39C@1239,3F754@33958,4I0DV@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation LEHHPAIP_01666 1140001.I571_02880 5e-29 134.8 Bacteria 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria COG3764@1,COG3764@2 NA|NA|NA M Sortase family LEHHPAIP_01667 1140001.I571_02879 5.6e-85 322.4 Enterococcaceae Bacteria 1TSCY@1239,4B3DY@81852,4I2HB@91061,COG4932@1,COG4932@2 NA|NA|NA M Gram-positive pilin backbone subunit 2, Cna-B-like domain LEHHPAIP_01668 1140001.I571_02252 4.7e-43 181.8 Enterococcaceae 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1UN9R@1239,4B6AY@81852,4HH56@91061,COG3764@1,COG3764@2 NA|NA|NA M Sortase family LEHHPAIP_01672 1033837.WANG_1100 1.9e-30 138.7 Lactobacillaceae higB-2 Bacteria 1U5P8@1239,3FAI9@33958,4II1M@91061,COG4737@1,COG4737@2 NA|NA|NA S RelE toxin of RelE / RelB toxin-antitoxin system LEHHPAIP_01673 1033837.WANG_1099 3.8e-21 107.5 Lactobacillaceae ko:K07726 ko00000,ko03000 Bacteria 1VEWZ@1239,3F82N@33958,4HP6G@91061,COG2944@1,COG2944@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins LEHHPAIP_01676 86416.Clopa_3153 3.3e-21 107.8 Clostridiaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,24HF9@186801,36IQ6@31979,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein LEHHPAIP_01683 1122147.AUEH01000001_gene517 3e-08 65.1 Lactobacillaceae Bacteria 1U74E@1239,29PW7@1,30AUI@2,3F8YN@33958,4IGZ1@91061 NA|NA|NA LEHHPAIP_01685 334390.LAF_0059 6.9e-67 260.4 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family LEHHPAIP_01687 1235801.C822_01042 1.1e-86 326.6 Lactobacillaceae endA ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease LEHHPAIP_01690 1235801.C822_00307 3e-126 458.4 Lactobacillaceae ko:K18640 ko00000,ko04812 Bacteria 1UJAK@1239,3FBWM@33958,4ITM7@91061,COG4972@1,COG4972@2 NA|NA|NA NU StbA protein LEHHPAIP_01692 388919.SSA_0155 5.2e-07 60.5 Streptococcus sanguinis Bacteria 1UACV@1239,1WS5P@1305,2AR9W@1,31GJT@2,4IKR3@91061 NA|NA|NA S Uncharacterized protein pXO2-11 LEHHPAIP_01693 1235801.C822_00299 9.7e-38 163.7 Lactobacillaceae Bacteria 1U7XV@1239,2BNGP@1,32H4W@2,3FAB0@33958,4IHV8@91061 NA|NA|NA LEHHPAIP_01694 1214217.ALNF01000025_gene946 4.2e-230 804.3 Bacilli trsE Bacteria 1W186@1239,4HA4T@91061,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase LEHHPAIP_01696 1033837.WANG_p1172 1.2e-28 134.4 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VW67@1239,3F41W@33958,4HWSY@91061,COG0791@1,COG0791@2 NA|NA|NA M CHAP domain LEHHPAIP_01698 1329250.WOSG25_070410 1.8e-07 63.2 Leuconostocaceae Bacteria 1U3C1@1239,29MH1@1,308EW@2,4AXH6@81850,4ID48@91061 NA|NA|NA LEHHPAIP_01699 1235801.C822_00292 1.7e-100 373.2 Lactobacillaceae Bacteria 1UIMF@1239,2AQ9M@1,31FFI@2,3FBVB@33958,4ISND@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) LEHHPAIP_01700 1423814.HMPREF0549_1105 1.6e-171 608.6 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1NJ@1239,3FCCR@33958,4HFWT@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid LEHHPAIP_01701 575594.ACOH01000018_gene1499 4.2e-49 203.4 Lactobacillaceae ebh ko:K08086 ko00000 Bacteria 1W39C@1239,3F754@33958,4I0DV@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation LEHHPAIP_01702 1203076.CAKF01000003_gene24 4.4e-48 197.6 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1A7@1239,3F655@33958,4HG0B@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase LEHHPAIP_01703 862514.HMPREF0623_1596 1.9e-134 485.3 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 LEHHPAIP_01704 334390.LAF_1569 3.3e-71 275.0 Lactobacillaceae ko:K07483,ko:K07497 ko00000 Bacteria 1V4FD@1239,3FBFG@33958,4IQ19@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain LEHHPAIP_01705 500635.MITSMUL_03779 6.3e-257 893.3 Negativicutes ade 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 R01244 RC00477 ko00000,ko00001,ko01000 Bacteria 1TP84@1239,4H304@909932,COG1001@1,COG1001@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family LEHHPAIP_01706 349123.Lreu23DRAFT_3553 3.8e-182 644.4 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease LEHHPAIP_01707 353496.LBU_0899 1.4e-163 582.4 Lactobacillaceae add 3.5.4.2,3.5.4.4 ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko01000 Bacteria 1U44B@1239,3F5RC@33958,4HCES@91061,COG1816@1,COG1816@2 NA|NA|NA F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism LEHHPAIP_01708 557436.Lreu_1613 0.0 1234.9 Lactobacillaceae nplT 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 R02112,R03122,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 1TNZ0@1239,3F41N@33958,4HB67@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family LEHHPAIP_01709 557436.Lreu_1614 2.5e-258 897.5 Lactobacillaceae ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1VSS5@1239,3F62S@33958,4HT1M@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator Superfamily LEHHPAIP_01710 405566.lhv_0260 1.8e-34 152.1 Lactobacillaceae 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1U7GV@1239,3F9ND@33958,4IHDA@91061,COG0827@1,COG0827@2,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits LEHHPAIP_01711 405566.lhv_0260 2e-109 402.5 Lactobacillaceae 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1U7GV@1239,3F9ND@33958,4IHDA@91061,COG0827@1,COG0827@2,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits LEHHPAIP_01712 557436.Lreu_1606 1.3e-224 785.4 Lactobacillaceae oxlT ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 1TPR9@1239,3F4XT@33958,4HB93@91061,COG2223@1,COG2223@2 NA|NA|NA P Major Facilitator Superfamily LEHHPAIP_01713 557436.Lreu_1605 8.6e-159 566.2 Lactobacillaceae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1TSUW@1239,3F598@33958,4HVQM@91061,COG0566@1,COG0566@2 NA|NA|NA J Methyltransferase LEHHPAIP_01714 349123.Lreu23DRAFT_4550 1.3e-18 98.2 Lactobacillaceae ywlG Bacteria 1V3H0@1239,3F66D@33958,4HH6F@91061,COG4475@1,COG4475@2 NA|NA|NA S Belongs to the UPF0340 family LEHHPAIP_01715 349123.Lreu23DRAFT_4549 1.3e-48 198.7 Lactobacillaceae Bacteria 1U72S@1239,2DKU2@1,30AT7@2,3F8WF@33958,4IGXB@91061 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE LEHHPAIP_01716 349123.Lreu23DRAFT_4548 1e-37 162.2 Lactobacillaceae Bacteria 1TU4U@1239,3F8GD@33958,4IGM3@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module LEHHPAIP_01717 1033837.WANG_1127 1.2e-179 636.0 Lactobacillaceae tnp2 Bacteria 1TQ93@1239,3F4RB@33958,4HC0Q@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM Transposase, IS204 IS1001 IS1096 IS1165 LEHHPAIP_01718 557436.Lreu_1041 1e-108 399.4 Lactobacillaceae mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K11733,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid LEHHPAIP_01720 349123.Lreu23DRAFT_3766 7.4e-67 259.6 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1UPNV@1239,3F6UK@33958,4IV86@91061,COG2337@1,COG2337@2 NA|NA|NA T Toxin-antitoxin system, toxin component, MazF family LEHHPAIP_01721 349123.Lreu23DRAFT_3767 5.2e-37 159.8 Lactobacillaceae ko:K18829 ko00000,ko02048 Bacteria 1U6MA@1239,2DKME@1,309X7@2,3F856@33958,4IGE5@91061 NA|NA|NA LEHHPAIP_01722 525309.HMPREF0494_1298 6.7e-07 62.8 Lactobacillaceae Bacteria 1W39C@1239,3F754@33958,4I0DV@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation LEHHPAIP_01723 349123.Lreu23DRAFT_3769 0.0 2192.2 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein LEHHPAIP_01724 557436.Lreu_1034 1e-142 512.7 Lactobacillaceae ywqE 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,3F3RT@33958,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM PHP domain protein LEHHPAIP_01725 349123.Lreu23DRAFT_3772 6.8e-209 733.0 Lactobacillaceae sbcD ko:K03547 ko00000,ko03400 Bacteria 1TQY6@1239,3F4A9@33958,4HAKB@91061,COG0420@1,COG0420@2 NA|NA|NA L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity LEHHPAIP_01726 349123.Lreu23DRAFT_3773 0.0 1670.6 Lactobacillaceae sbcC ko:K03546 ko00000,ko03400 Bacteria 1TPCS@1239,3F3TE@33958,4H9Q3@91061,COG0419@1,COG0419@2 NA|NA|NA L Putative exonuclease SbcCD, C subunit LEHHPAIP_01727 349123.Lreu23DRAFT_4291 0.0 1617.4 Lactobacillaceae 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1V7CU@1239,3FBVE@33958,4HCZJ@91061,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 LEHHPAIP_01728 349123.Lreu23DRAFT_4292 2.1e-117 428.3 Lactobacillaceae rfbP 2.7.8.6 ko:K00996 ko00000,ko01000,ko01005 Bacteria 1V2YT@1239,3FBFI@33958,4IQ2I@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase LEHHPAIP_01729 557436.Lreu_1376 1e-170 605.9 Lactobacillaceae yfdH 2.4.2.53 ko:K10012,ko:K12999,ko:K13670 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000 4.D.2.1.8 GT2 Bacteria 1UHWE@1239,3F3JX@33958,4ISA4@91061,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase, group 2 family protein LEHHPAIP_01730 557436.Lreu_1377 1.9e-146 525.0 Lactobacillaceae cps1D Bacteria 1U6EG@1239,3F539@33958,4HG4F@91061,COG1442@1,COG1442@2 NA|NA|NA M Domain of unknown function (DUF4422) LEHHPAIP_01731 557436.Lreu_1378 1.2e-135 489.2 Lactobacillaceae recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1V72V@1239,3F4BY@33958,4HJ7R@91061,COG2137@1,COG2137@2 NA|NA|NA S Regulatory protein RecX LEHHPAIP_01732 557436.Lreu_1379 4.9e-31 139.8 Lactobacillaceae Bacteria 1U76N@1239,29PXV@1,30AW8@2,3F91K@33958,4IH1G@91061 NA|NA|NA LEHHPAIP_01733 557436.Lreu_1380 6.6e-34 149.4 Lactobacillaceae Bacteria 1VKCM@1239,2DR42@1,33A2M@2,3F8R5@33958,4HRAS@91061 NA|NA|NA S Protein of unknown function (DUF2922) LEHHPAIP_01734 349123.Lreu23DRAFT_4298 1.8e-143 515.4 Lactobacillaceae yihY ko:K07058 ko00000 Bacteria 1U7HM@1239,3F4TC@33958,4H9MJ@91061,COG1295@1,COG1295@2 NA|NA|NA S Belongs to the UPF0761 family LEHHPAIP_01735 349123.Lreu23DRAFT_4299 3.4e-280 970.3 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid LEHHPAIP_01736 349123.Lreu23DRAFT_4300 9.5e-256 889.0 Lactobacillaceae ko:K03758 ko00000,ko02000 2.A.3.2 Bacteria 1TSSB@1239,3F3P5@33958,4HA92@91061,COG0531@1,COG0531@2 NA|NA|NA E Arginine ornithine antiporter LEHHPAIP_01737 349123.Lreu23DRAFT_4301 1.6e-221 775.0 Lactobacillaceae arcT 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1TQPD@1239,3F3PZ@33958,4HE7P@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase LEHHPAIP_01738 349123.Lreu23DRAFT_4302 1.3e-167 595.5 Lactobacillaceae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1TQC1@1239,3F3MK@33958,4H9S9@91061,COG0024@1,COG0024@2 NA|NA|NA E Methionine Aminopeptidase LEHHPAIP_01739 557436.Lreu_1386 1.4e-78 298.9 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1V7AG@1239,3F6HY@33958,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin LEHHPAIP_01740 1423814.HMPREF0549_1476 1.3e-67 262.3 Lactobacillaceae gtcA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VESW@1239,3F4GH@33958,4HNK7@91061,COG2246@1,COG2246@2 NA|NA|NA S Teichoic acid glycosylation protein LEHHPAIP_01741 525365.HMPREF0548_2001 7.1e-56 223.4 Lactobacillaceae Bacteria 1VDSZ@1239,2ZQQ1@2,3F6N4@33958,4HXVX@91061,arCOG04234@1 NA|NA|NA LEHHPAIP_01742 557436.Lreu_1389 9e-209 732.6 Lactobacillaceae mnaA 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1TQZT@1239,3F3KQ@33958,4HBI3@91061,COG0381@1,COG0381@2 NA|NA|NA G Belongs to the UDP-N-acetylglucosamine 2-epimerase family LEHHPAIP_01744 349123.Lreu23DRAFT_4307 1.9e-231 808.1 Lactobacillaceae yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 Bacteria 1TQ9R@1239,3F4K8@33958,4HANR@91061,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase LEHHPAIP_01745 557436.Lreu_1391 5.9e-191 673.3 Lactobacillaceae mocA ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3F4EV@33958,4HCIG@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase LEHHPAIP_01746 349123.Lreu23DRAFT_4309 9.1e-62 242.7 Lactobacillaceae Bacteria 1VNS7@1239,2EGZM@1,33ARR@2,3F83W@33958,4HSZW@91061 NA|NA|NA S Domain of unknown function (DUF4828) LEHHPAIP_01747 349123.Lreu23DRAFT_4310 1.1e-104 386.0 Lactobacillaceae yvdD 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1UKED@1239,3F5U4@33958,4HE2X@91061,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family LEHHPAIP_01748 349123.Lreu23DRAFT_4311 1.5e-164 585.5 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily LEHHPAIP_01749 557436.Lreu_1395 2.2e-295 1020.8 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family LEHHPAIP_01750 557436.Lreu_1396 3e-195 687.6 Lactobacillaceae Bacteria 1VBKU@1239,2DI63@1,32UAI@2,3F66K@33958,4HUJH@91061 NA|NA|NA S Protein of unknown function (DUF3114) LEHHPAIP_01751 349123.Lreu23DRAFT_4314 5.5e-80 303.5 Bacteria yjcF GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.4.33,4.4.1.8 ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941,R10223 RC00056,RC00069,RC00382,RC00477,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007,ko03016 Bacteria COG2153@1,COG2153@2 NA|NA|NA K protein acetylation LEHHPAIP_01752 349123.Lreu23DRAFT_4315 7.3e-116 423.3 Lactobacillaceae ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V779@1239,3F3QH@33958,4HIX1@91061,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family LEHHPAIP_01753 349123.Lreu23DRAFT_4268 1.9e-155 555.1 Lactobacillaceae rfbD 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP71@1239,3F4QS@33958,4HBXF@91061,COG1091@1,COG1091@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose LEHHPAIP_01754 349123.Lreu23DRAFT_4269 7.8e-199 699.5 Lactobacillaceae rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,3F3R6@33958,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily LEHHPAIP_01755 349123.Lreu23DRAFT_4270 1.6e-108 398.7 Lactobacillaceae rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRVB@1239,3F4FN@33958,4HFQB@91061,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose LEHHPAIP_01756 349123.Lreu23DRAFT_4271 9.2e-161 572.8 Lactobacillaceae rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 1V301@1239,3F4F8@33958,4H9R0@91061,COG1209@1,COG1209@2 NA|NA|NA H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis LEHHPAIP_01757 349123.Lreu23DRAFT_4273 0.0 1374.0 Lactobacillaceae 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 1UYRM@1239,3F4XJ@33958,4HAU6@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase LEHHPAIP_01758 944562.HMPREF9102_0233 1.8e-134 486.5 Bacilli Bacteria 1V8VK@1239,2DM6I@1,31X8H@2,4IR1A@91061 NA|NA|NA LEHHPAIP_01759 944562.HMPREF9102_0232 1.2e-145 522.7 Lactobacillaceae rfbJ Bacteria 1UI8D@1239,3F49C@33958,4IST0@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 LEHHPAIP_01760 203120.LEUM_1399 5.8e-83 315.5 Leuconostocaceae Bacteria 1V4M1@1239,2DGTK@1,2ZX8T@2,4AY6N@81850,4ISSZ@91061 NA|NA|NA LEHHPAIP_01761 353496.LBU_1584 2e-72 279.6 Lactobacillaceae Bacteria 1V0QX@1239,3F60P@33958,4HFH3@91061,COG3274@1,COG3274@2 NA|NA|NA S Acyltransferase family LEHHPAIP_01762 272621.LBA1731 1.3e-80 306.6 Lactobacillaceae glfT1 1.1.1.133 ko:K00067,ko:K07011 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4NS@1239,3F6P7@33958,4HHDW@91061,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 LEHHPAIP_01763 349123.Lreu23DRAFT_4278 1.8e-67 262.7 Lactobacillaceae Bacteria 1W68V@1239,3F669@33958,4IFBY@91061,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family LEHHPAIP_01764 944562.HMPREF9102_0207 3.4e-76 292.0 Lactobacillaceae rgpB ko:K12997 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1V2EP@1239,3F74Y@33958,4HHPV@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 LEHHPAIP_01765 944562.HMPREF9102_0199 3.9e-28 131.7 Lactobacillaceae ko:K16692 ko00000,ko01000,ko01001 Bacteria 1W5Q7@1239,3F84M@33958,4HZIW@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein LEHHPAIP_01766 944562.HMPREF9102_0198 3.1e-90 339.0 Lactobacillaceae cps3F Bacteria 1VKUY@1239,2DN9M@1,32W9S@2,3F629@33958,4IPMK@91061 NA|NA|NA LEHHPAIP_01767 1423806.JCM15457_1205 4.7e-76 291.6 Lactobacillaceae Bacteria 1V8J0@1239,3FBD0@33958,4HVPH@91061,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups LEHHPAIP_01768 349123.Lreu23DRAFT_4285 3.2e-211 741.1 Lactobacillaceae rfbX Bacteria 1TP7R@1239,3F48Q@33958,4HC84@91061,COG2244@1,COG2244@2 NA|NA|NA S Membrane protein involved in the export of O-antigen and teichoic acid LEHHPAIP_01769 349123.Lreu23DRAFT_4286 3.1e-217 760.8 Lactobacillaceae glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,3F52G@33958,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase LEHHPAIP_01770 349123.Lreu23DRAFT_4289 6.1e-25 120.9 Lactobacillaceae Bacteria 1U6E7@1239,2CETN@1,30AAE@2,3F7PU@33958,4IG5Z@91061 NA|NA|NA LEHHPAIP_01771 349123.Lreu23DRAFT_4290 0.0 1503.0 Lactobacillaceae Bacteria 1V7GB@1239,3F5VT@33958,4I28M@91061,COG4193@1,COG4193@2,COG4990@1,COG4990@2 NA|NA|NA G Peptidase_C39 like family LEHHPAIP_01772 557436.Lreu_0246 1.8e-99 368.6 Lactobacillaceae glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0040008,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045926,GO:0046394,GO:0046395,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 iB21_1397.B21_01492,iECBD_1354.ECBD_2118,iECB_1328.ECB_01481,iECD_1391.ECD_01481,iYL1228.KPN_01636,iYO844.BSU02430 Bacteria 1TP64@1239,3F4NW@33958,4H9XA@91061,COG2066@1,COG2066@2 NA|NA|NA E Belongs to the glutaminase family LEHHPAIP_01773 557436.Lreu_0246 4.5e-55 220.3 Lactobacillaceae glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0040008,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045926,GO:0046394,GO:0046395,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 iB21_1397.B21_01492,iECBD_1354.ECBD_2118,iECB_1328.ECB_01481,iECD_1391.ECD_01481,iYL1228.KPN_01636,iYO844.BSU02430 Bacteria 1TP64@1239,3F4NW@33958,4H9XA@91061,COG2066@1,COG2066@2 NA|NA|NA E Belongs to the glutaminase family LEHHPAIP_01774 557436.Lreu_0249 1.5e-252 878.2 Lactobacillaceae dltD ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TSZU@1239,3F3WE@33958,4HC3H@91061,COG3966@1,COG3966@2 NA|NA|NA M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) LEHHPAIP_01775 349123.Lreu23DRAFT_5117 2.8e-35 154.1 Lactobacillaceae dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VFQI@1239,3F7Q1@33958,4HNIH@91061,COG0236@1,COG0236@2 NA|NA|NA J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall LEHHPAIP_01776 557436.Lreu_0251 1.1e-233 815.5 Lactobacillaceae dltB ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TP52@1239,3F4KK@33958,4HBQG@91061,COG1696@1,COG1696@2 NA|NA|NA M MBOAT, membrane-bound O-acyltransferase family LEHHPAIP_01777 349123.Lreu23DRAFT_5119 2.2e-295 1020.8 Lactobacillaceae dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPTH@1239,3F49R@33958,4HAHU@91061,COG1020@1,COG1020@2 NA|NA|NA H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall LEHHPAIP_01779 557436.Lreu_0254 1.1e-59 235.7 Lactobacillaceae acpS 2.7.6.3,2.7.8.7,5.1.1.1 ko:K00950,ko:K00997,ko:K01775 ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502 M00126,M00841 R00401,R01625,R03503 RC00002,RC00017,RC00285 ko00000,ko00001,ko00002,ko01000,ko01011 iYO844.BSU04620 Bacteria 1VA0T@1239,3F6HC@33958,4HKBI@91061,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein LEHHPAIP_01780 349123.Lreu23DRAFT_5122 2e-208 731.5 Lactobacillaceae alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1TNYY@1239,3F3X2@33958,4HA95@91061,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids LEHHPAIP_01781 557436.Lreu_0256 9.4e-62 242.7 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1V6DK@1239,3F6Y9@33958,4HGXF@91061,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module LEHHPAIP_01782 349123.Lreu23DRAFT_5124 3.1e-251 874.0 Lactobacillaceae Bacteria 1TTBN@1239,3F4YG@33958,4HA3B@91061,COG1457@1,COG1457@2 NA|NA|NA U Belongs to the purine-cytosine permease (2.A.39) family LEHHPAIP_01783 557436.Lreu_0258 2.3e-242 844.3 Lactobacillaceae codA 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 Bacteria 1TRK2@1239,3F4JP@33958,4HAAV@91061,COG0402@1,COG0402@2 NA|NA|NA F cytosine deaminase LEHHPAIP_01784 557436.Lreu_0259 6.4e-145 520.0 Lactobacillaceae tesE ko:K02509 ko00350,ko01120,map00350,map01120 R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 Bacteria 1TQVG@1239,3F515@33958,4HBMC@91061,COG3971@1,COG3971@2 NA|NA|NA Q hydratase LEHHPAIP_01785 557436.Lreu_0932 0.0 1097.8 Lactobacillaceae FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,3F3PS@33958,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K Fibronectin-binding protein LEHHPAIP_01786 557436.Lreu_0931 0.0 1589.7 Lactobacillaceae carB 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRNP@1239,3FC3W@33958,4HTJU@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase LEHHPAIP_01787 349123.Lreu23DRAFT_3288 1.4e-206 725.3 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1VTN5@1239,3FC4C@33958,4HT8S@91061,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family LEHHPAIP_01788 557436.Lreu_0929 2.2e-173 614.8 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TPCM@1239,3F3P6@33958,4HBG2@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil LEHHPAIP_01789 557436.Lreu_0928 1.7e-73 282.0 Lactobacillaceae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1VA9R@1239,3F66R@33958,4HIR4@91061,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins LEHHPAIP_01790 349123.Lreu23DRAFT_3285 5.6e-65 253.4 Lactobacillaceae esbA Bacteria 1W31C@1239,2BZWG@1,2ZPAS@2,3F6SQ@33958,4I09H@91061 NA|NA|NA S Family of unknown function (DUF5322) LEHHPAIP_01791 349123.Lreu23DRAFT_3284 9e-71 272.7 Lactobacillaceae rnhA 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1VH2B@1239,3F7JC@33958,4HIY9@91061,COG0328@1,COG0328@2 NA|NA|NA L Ribonuclease HI LEHHPAIP_01792 349123.Lreu23DRAFT_3282 4.3e-222 776.9 Lactobacillaceae rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1TP0X@1239,3F3NZ@33958,4HBKY@91061,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily LEHHPAIP_01793 557436.Lreu_0924 4e-81 307.4 Lactobacillaceae ko:K03647 ko00000 Bacteria 1VWJA@1239,3FBB8@33958,4HW5I@91061,COG1780@1,COG1780@2 NA|NA|NA F Belongs to the NrdI family LEHHPAIP_01794 349123.Lreu23DRAFT_3279 1.2e-42 179.1 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1VEQ4@1239,3F6VZ@33958,4HNP1@91061,COG3599@1,COG3599@2 NA|NA|NA D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation LEHHPAIP_01795 349123.Lreu23DRAFT_3278 3.2e-101 374.4 Lactobacillaceae ypsA Bacteria 1V6SM@1239,3F4MR@33958,4HJGM@91061,COG4474@1,COG4474@2 NA|NA|NA S Belongs to the UPF0398 family LEHHPAIP_01796 557436.Lreu_0921 5.8e-117 426.8 Lactobacillaceae recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03700 ko00000,ko03400 Bacteria 1V3S4@1239,3F4DG@33958,4HGZ7@91061,COG3331@1,COG3331@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation LEHHPAIP_01797 349123.Lreu23DRAFT_3276 0.0 1230.3 Lactobacillaceae ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F424@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein 1A LEHHPAIP_01798 557436.Lreu_0919 1.3e-160 572.4 Lactobacillaceae Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family LEHHPAIP_01799 349123.Lreu23DRAFT_3274 8.1e-123 446.4 Lactobacillaceae dnaD ko:K02086 ko00000 Bacteria 1V283@1239,3F4FF@33958,4HFP3@91061,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein LEHHPAIP_01800 557436.Lreu_0917 9.9e-86 322.8 Lactobacillaceae ypmB Bacteria 1VA2H@1239,3F4MM@33958,4HNMM@91061,COG5353@1,COG5353@2 NA|NA|NA S Protein conserved in bacteria LEHHPAIP_01801 557436.Lreu_0916 0.0 1835.8 Lactobacillaceae dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQHQ@1239,3F4KA@33958,4HB2Y@91061,COG0847@1,COG0847@2,COG1199@1,COG1199@2 NA|NA|NA L helicase involved in DNA repair and perhaps also replication LEHHPAIP_01802 557436.Lreu_0915 6.3e-171 606.7 Lactobacillaceae mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT5C@1239,3F3TW@33958,4HAQQ@91061,COG1577@1,COG1577@2 NA|NA|NA I mevalonate kinase LEHHPAIP_01803 349123.Lreu23DRAFT_3270 7.4e-167 593.2 Lactobacillaceae mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXR@1239,3F4B5@33958,4HAM6@91061,COG3407@1,COG3407@2 NA|NA|NA I diphosphomevalonate decarboxylase LEHHPAIP_01804 349123.Lreu23DRAFT_3269 1.8e-212 745.0 Lactobacillaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,3F3RZ@33958,4HC93@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase LEHHPAIP_01805 349123.Lreu23DRAFT_3268 6.4e-193 679.9 Lactobacillaceae fni 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQZ3@1239,3F3UY@33958,4HAMV@91061,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) LEHHPAIP_01806 349123.Lreu23DRAFT_3267 9.3e-86 322.8 Lactobacillaceae ko:K08996 ko00000 Bacteria 1VX0K@1239,3F6A5@33958,4HX2R@91061,COG3477@1,COG3477@2 NA|NA|NA S Protein of unknown function (DUF1440) LEHHPAIP_01807 1074451.CRL705_1887 4.9e-160 570.5 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair LEHHPAIP_01808 557436.Lreu_0244 8.7e-252 875.9 Lactobacillaceae cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F46Q@33958,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity LEHHPAIP_01809 557436.Lreu_0243 1.9e-256 891.3 Lactobacillaceae murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1VT78@1239,3F4SK@33958,4HACR@91061,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein LEHHPAIP_01810 349123.Lreu23DRAFT_5111 2e-158 565.1 Lactobacillaceae htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1TP23@1239,3F40Z@33958,4HB11@91061,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family LEHHPAIP_01811 557436.Lreu_0241 7e-93 346.7 Lactobacillaceae lemA ko:K03744 ko00000 Bacteria 1V3Z0@1239,3F4TF@33958,4HH6H@91061,COG1704@1,COG1704@2 NA|NA|NA S LemA family LEHHPAIP_01812 557436.Lreu_0240 8e-87 326.2 Lactobacillaceae ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1V6SG@1239,3F74A@33958,4HIZN@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family LEHHPAIP_01813 557436.Lreu_0239 9.2e-121 439.5 Lactobacillaceae pgm3 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQF1@1239,3F4RY@33958,4I2XH@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family LEHHPAIP_01814 557436.Lreu_0238 1.3e-162 578.9 Lactobacillaceae fba 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,3F4EF@33958,4H9ZU@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-1,6-bisphosphate aldolase, class II LEHHPAIP_01815 557436.Lreu_0237 9.8e-138 496.1 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F9MM@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) LEHHPAIP_01816 525309.HMPREF0494_1039 2.3e-158 565.8 Lactobacillaceae 3.2.1.55 ko:K01209 ko00520,map00520 R01762 ko00000,ko00001,ko01000 GH51 Bacteria 1TPM0@1239,3F5KT@33958,4HC24@91061,COG1653@1,COG1653@2 NA|NA|NA G Right handed beta helix region LEHHPAIP_01817 1136177.KCA1_1648 0.0 1211.4 Lactobacillaceae ppsA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 Bacteria 1TPK8@1239,3F3U1@33958,4ISER@91061,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate LEHHPAIP_01818 349123.Lreu23DRAFT_5105 7.3e-116 423.3 Lactobacillaceae srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V83Z@1239,3F54V@33958,4HJV9@91061,COG3764@1,COG3764@2 NA|NA|NA M sortase family LEHHPAIP_01819 349123.Lreu23DRAFT_5104 3.1e-164 584.3 Lactobacillaceae Bacteria 1V8NG@1239,3F41V@33958,4HJ22@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) LEHHPAIP_01820 557436.Lreu_0234 4.5e-236 823.5 Lactobacillaceae pts13C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1V5SI@1239,3F3Z5@33958,4HJTK@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane LEHHPAIP_01821 349123.Lreu23DRAFT_5102 4.6e-41 173.3 Lactobacillaceae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGU@1239,3F7D7@33958,4HKF0@91061,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 LEHHPAIP_01822 557436.Lreu_0232 2e-236 824.7 Lactobacillaceae murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 iYO844.BSU37100 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine LEHHPAIP_01823 557436.Lreu_0230 0.0 1075.1 Lactobacillaceae pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS01075,iNJ661.Rv1699 Bacteria 1TP34@1239,3F42X@33958,4H9X6@91061,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates LEHHPAIP_01824 349123.Lreu23DRAFT_5099 8.7e-51 206.8 Lactobacillaceae rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Bacteria 1V6WX@1239,3F55D@33958,4HIUK@91061,COG3343@1,COG3343@2 NA|NA|NA K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling LEHHPAIP_01825 349123.Lreu23DRAFT_5098 8.2e-67 259.6 Lactobacillaceae ywiB Bacteria 1V8IZ@1239,3F6AI@33958,4HIW0@91061,COG4506@1,COG4506@2 NA|NA|NA S Domain of unknown function (DUF1934) LEHHPAIP_01826 1074451.CRL705_1887 4.1e-159 567.4 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair LEHHPAIP_01827 557436.Lreu_0933 2.1e-160 571.6 Lactobacillaceae degV Bacteria 1TRM7@1239,3F40W@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family LEHHPAIP_01828 349123.Lreu23DRAFT_3292 1.1e-89 336.3 Lactobacillaceae Bacteria 1U6MD@1239,29PI5@1,30AGA@2,3F85A@33958,4IGE8@91061 NA|NA|NA LEHHPAIP_01829 349123.Lreu23DRAFT_3293 1.1e-116 426.0 Lactobacillaceae ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,3F3PN@33958,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. LEHHPAIP_01830 557436.Lreu_0936 8.7e-156 556.2 Lactobacillaceae gspA Bacteria 1UY8Y@1239,3F4YJ@33958,4HBAE@91061,COG1442@1,COG1442@2 NA|NA|NA M family 8 LEHHPAIP_01831 557436.Lreu_0937 1.1e-153 549.3 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase LEHHPAIP_01832 349123.Lreu23DRAFT_3298 1.5e-94 352.1 Lactobacillaceae Bacteria 1VZ11@1239,3FBE8@33958,4HH5T@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain LEHHPAIP_01833 557436.Lreu_0940 8.7e-243 845.9 Lactobacillaceae XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,3F4H2@33958,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein LEHHPAIP_01834 349123.Lreu23DRAFT_3301 1.4e-38 165.2 Lactobacillaceae gcvR ko:K07166 ko00000 Bacteria 1VENW@1239,3F811@33958,4HNJ4@91061,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family LEHHPAIP_01835 557436.Lreu_0942 1.7e-170 605.1 Lactobacillaceae 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase LEHHPAIP_01836 557436.Lreu_0943 1.5e-158 565.5 Lactobacillaceae Bacteria 1TP77@1239,3FC6P@33958,4HDPG@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain protein LEHHPAIP_01837 557436.Lreu_0944 2.6e-77 294.7 Lactobacillaceae Bacteria 1VF1B@1239,3FBG1@33958,4IQ5Z@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin LEHHPAIP_01838 349123.Lreu23DRAFT_3304 1.5e-77 295.4 Lactobacillaceae yphH Bacteria 1V3TP@1239,3FBIJ@33958,4IQRJ@91061,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain LEHHPAIP_01839 349123.Lreu23DRAFT_3305 1.7e-73 282.0 Lactobacillaceae yeaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V7EH@1239,3FBPV@33958,4IRTA@91061,COG2707@1,COG2707@2 NA|NA|NA S UPF0756 membrane protein LEHHPAIP_01840 349123.Lreu23DRAFT_3306 6.2e-244 849.7 Lactobacillaceae Bacteria 1TPRN@1239,3F3XY@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_01841 557436.Lreu_0948 5e-75 287.0 Lactobacillaceae copY Bacteria 1VA7Q@1239,3F7D0@33958,4HKGF@91061,COG3682@1,COG3682@2 NA|NA|NA K Copper transport repressor CopY TcrY LEHHPAIP_01842 557436.Lreu_0949 8.5e-246 855.9 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain LEHHPAIP_01843 557436.Lreu_0950 0.0 1103.2 Lactobacillaceae ubiB ko:K03688 ko00000 Bacteria 1TPIV@1239,3F51C@33958,4HBW3@91061,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family LEHHPAIP_01844 349123.Lreu23DRAFT_3310 1.5e-144 518.8 Lactobacillaceae Bacteria 1VA42@1239,3FBMH@33958,4IR5W@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain LEHHPAIP_01845 349123.Lreu23DRAFT_3929 2.1e-67 261.5 Lactobacillaceae Bacteria 1V7D7@1239,3F6XZ@33958,4HIGP@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LEHHPAIP_01846 557436.Lreu_0953 1.6e-56 225.3 Bacteria crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity LEHHPAIP_01847 349123.Lreu23DRAFT_3927 4.5e-55 220.3 Lactobacillaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1VM30@1239,3F8A8@33958,4HRC4@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity LEHHPAIP_01848 349123.Lreu23DRAFT_3926 0.0 1615.1 Lactobacillaceae uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP0A@1239,3F3V4@33958,4HTDZ@91061,COG0178@1,COG0178@2 NA|NA|NA L excinuclease ABC, A subunit LEHHPAIP_01849 349123.Lreu23DRAFT_3925 3.7e-120 437.6 Lactobacillaceae Bacteria 1V6V7@1239,3F417@33958,4HITM@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein LEHHPAIP_01850 557436.Lreu_0957 2.3e-229 801.2 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) LEHHPAIP_01851 557436.Lreu_0958 0.0 1187.6 Lactobacillaceae dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP37@1239,3F4RN@33958,4H9QW@91061,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) LEHHPAIP_01853 349123.Lreu23DRAFT_3921 6.6e-254 882.9 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease LEHHPAIP_01854 557436.Lreu_0961 7.2e-158 563.1 Lactobacillaceae endA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K15051 ko00000 Bacteria 1UIKC@1239,2EW1F@1,33PER@2,3FBVF@33958,4ISM6@91061 NA|NA|NA V DNA/RNA non-specific endonuclease LEHHPAIP_01855 349123.Lreu23DRAFT_3919 0.0 1529.6 Lactobacillaceae ko:K11009 ko00000,ko02042 Bacteria 1V3AR@1239,3F53M@33958,4HWUN@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol LEHHPAIP_01856 557436.Lreu_0964 2.3e-41 174.5 Lactobacillaceae ybaN ko:K09790 ko00000 Bacteria 1U6FY@1239,3F7TW@33958,4IG7Y@91061,COG2832@1,COG2832@2 NA|NA|NA S Protein of unknown function (DUF454) LEHHPAIP_01857 349123.Lreu23DRAFT_3916 1.6e-71 275.4 Lactobacillaceae Bacteria 1VG8C@1239,2C9NT@1,32ZGB@2,3F749@33958,4HN0V@91061 NA|NA|NA S Protein of unknown function (DUF3290) LEHHPAIP_01858 349123.Lreu23DRAFT_3915 4.7e-114 417.2 Lactobacillaceae yviA Bacteria 1TPNF@1239,3FC4B@33958,4HIDY@91061,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) LEHHPAIP_01859 349123.Lreu23DRAFT_3914 2.2e-162 578.2 Lactobacillaceae Bacteria 1V910@1239,3F5UB@33958,4HF90@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) LEHHPAIP_01860 349123.Lreu23DRAFT_3913 2e-18 97.4 Lactobacillaceae Bacteria 1U6ZH@1239,29PS9@1,30AQH@2,3F8RU@33958,4IGTS@91061 NA|NA|NA LEHHPAIP_01861 349123.Lreu23DRAFT_3912 2.1e-90 338.2 Lactobacillaceae ntd 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1VY4Q@1239,3F5CB@33958,4HXB4@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside LEHHPAIP_01862 557436.Lreu_0971 3.3e-152 544.3 Lactobacillaceae 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V2JE@1239,3F3Z7@33958,4HWAW@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase LEHHPAIP_01863 349123.Lreu23DRAFT_3910 8.9e-41 172.9 Lactobacillaceae yrvD ko:K08992 ko00000 Bacteria 1VGMG@1239,3F73I@33958,4HQ29@91061,COG5416@1,COG5416@2 NA|NA|NA S Pfam:DUF1049 LEHHPAIP_01865 1033837.WANG_p1079 3.3e-35 154.5 Lactobacillaceae Bacteria 1VHME@1239,3F7IG@33958,4IRT3@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) LEHHPAIP_01866 1203076.CAKF01000022_gene645 8.5e-20 102.8 Lactobacillaceae Bacteria 1VMY1@1239,3F814@33958,4HRA4@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins LEHHPAIP_01867 557436.Lreu_0978 8.8e-164 582.8 Bacilli Bacteria 1V83G@1239,4HMC4@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold LEHHPAIP_01868 349123.Lreu23DRAFT_3846 1e-111 409.5 Lactobacillaceae frnE Bacteria 1TZ1N@1239,3F5IF@33958,4HEBF@91061,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain LEHHPAIP_01869 349123.Lreu23DRAFT_3203 0.0 1260.7 Lactobacillaceae parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQCF@1239,3F430@33958,4H9UC@91061,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule LEHHPAIP_01870 557436.Lreu_0783 0.0 1567.0 Lactobacillaceae parC GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TRE7@1239,3F3MJ@33958,4HAQB@91061,COG0188@1,COG0188@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule LEHHPAIP_01871 557436.Lreu_0784 8.1e-79 299.7 Lactobacillaceae Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain LEHHPAIP_01872 557436.Lreu_0785 3.9e-173 614.0 Lactobacillaceae ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TPH6@1239,3F3PJ@33958,4H9T8@91061,COG1227@1,COG1227@2 NA|NA|NA C inorganic pyrophosphatase LEHHPAIP_01873 557436.Lreu_0787 2.7e-67 261.2 Lactobacillaceae yqkB Bacteria 1VK6M@1239,3F7JD@33958,4HRFS@91061,COG4918@1,COG4918@2 NA|NA|NA S Belongs to the HesB IscA family LEHHPAIP_01874 349123.Lreu23DRAFT_3209 1.1e-25 122.1 Lactobacillaceae Bacteria 1U6YT@1239,29PRS@1,30APZ@2,3F8QU@33958,4IGT0@91061 NA|NA|NA LEHHPAIP_01876 557436.Lreu_0789 1.6e-85 322.0 Lactobacillaceae ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1V3V3@1239,3F70T@33958,4HHNY@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain LEHHPAIP_01877 349123.Lreu23DRAFT_3212 3.7e-61 240.7 Lactobacillaceae asp Bacteria 1V8FM@1239,3F77J@33958,4HJ0H@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function LEHHPAIP_01878 349123.Lreu23DRAFT_3213 3.6e-25 120.2 Lactobacillaceae Bacteria 1U6YP@1239,29PRP@1,30APW@2,3F8QP@33958,4IGSW@91061 NA|NA|NA LEHHPAIP_01879 349123.Lreu23DRAFT_3214 6.7e-93 346.7 Lactobacillaceae Bacteria 1U65I@1239,29P5M@1,30A3T@2,3F746@33958,4IFVD@91061 NA|NA|NA LEHHPAIP_01880 557436.Lreu_0793 4.1e-289 1000.0 Lactobacillaceae gntK 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family LEHHPAIP_01881 349123.Lreu23DRAFT_3216 4.9e-182 643.7 Lactobacillaceae ko:K02525 ko00000,ko03000 Bacteria 1TQSY@1239,3FC5E@33958,4HAJI@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family LEHHPAIP_01882 557436.Lreu_0795 2.7e-197 694.5 Lactobacillaceae gntT GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015128,GO:0015144,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K03299,ko:K06155 ko00000,ko02000 2.A.8,2.A.8.1.4 Bacteria 1TQ14@1239,3F3V0@33958,4HB0Y@91061,COG2610@1,COG2610@2 NA|NA|NA EG Gluconate LEHHPAIP_01883 557436.Lreu_0796 3.7e-235 820.5 Bacilli int ko:K06400 ko00000 Bacteria 1TPUG@1239,4HB3H@91061,COG1961@1,COG1961@2 NA|NA|NA L COG1961 Site-specific recombinases, DNA invertase Pin homologs LEHHPAIP_01887 557436.Lreu_0799 4.9e-72 276.9 Lactobacillaceae Bacteria 1VMA9@1239,2ER3F@1,33IP2@2,3F82G@33958,4HR4D@91061 NA|NA|NA LEHHPAIP_01888 1235801.C822_00104 3.5e-20 104.8 Lactobacillaceae Bacteria 1W1K0@1239,3F81Z@33958,4IGCD@91061,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase LEHHPAIP_01889 349123.Lreu23DRAFT_4033 7.5e-41 172.9 Lactobacillaceae ps115 Bacteria 1VEP9@1239,3F871@33958,4HPCR@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins LEHHPAIP_01890 525309.HMPREF0494_1805 2.6e-13 80.9 Lactobacillaceae Bacteria 1U71B@1239,29PTX@1,30AS3@2,3F8UQ@33958,4IGVS@91061 NA|NA|NA LEHHPAIP_01892 1158607.UAU_01711 7.8e-12 76.3 Enterococcaceae Bacteria 1U7FJ@1239,29Q41@1,30B2R@2,4B5CZ@81852,4ICPZ@91061 NA|NA|NA LEHHPAIP_01893 557436.Lreu_1142 1.1e-112 412.9 Lactobacillaceae ko:K07741 ko00000 Bacteria 1TPKA@1239,3F471@33958,4HFGH@91061,COG3617@1,COG3617@2,COG3645@1,COG3645@2 NA|NA|NA K BRO family, N-terminal domain LEHHPAIP_01898 557436.Lreu_0806 6.5e-33 146.0 Lactobacillaceae Bacteria 1U6SN@1239,2CF9P@1,30AJT@2,3F8F3@33958,4IGK7@91061 NA|NA|NA LEHHPAIP_01902 543734.LCABL_13050 8.7e-64 250.8 Lactobacillaceae recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K07455 ko00000,ko03400 Bacteria 1UNDF@1239,3F6D8@33958,4HB2T@91061,COG3723@1,COG3723@2 NA|NA|NA L RecT family LEHHPAIP_01903 947980.E9LUM4_9CAUD 3.5e-67 261.9 Siphoviridae Viruses 4QBP3@10239,4QM06@10699,4QPEQ@28883,4QVAZ@35237 NA|NA|NA S PDDEXK-like domain of unknown function (DUF3799) LEHHPAIP_01904 1140001.I571_02085 1.1e-22 114.0 Enterococcaceae Bacteria 1VHH7@1239,4B2D6@81852,4HK51@91061,COG3935@1,COG3935@2 NA|NA|NA L Replication initiation and membrane attachment LEHHPAIP_01905 557436.Lreu_0814 7.3e-26 123.2 Lactobacillaceae Bacteria 1U8AU@1239,2AIZB@1,319HB@2,3FAS8@33958,4II8T@91061 NA|NA|NA LEHHPAIP_01908 97137.C821_00091 3.5e-38 165.2 Lactobacillaceae Bacteria 1V7KA@1239,3F7GZ@33958,4HK0P@91061,COG3646@1,COG3646@2 NA|NA|NA S ORF6C domain LEHHPAIP_01910 349123.Lreu23DRAFT_4013 1e-28 132.1 Lactobacillaceae Bacteria 1U8FD@1239,2AYWW@1,31R2K@2,3FAX9@33958,4IID9@91061 NA|NA|NA LEHHPAIP_01918 944562.HMPREF9102_0402 2.4e-33 148.7 Lactobacillaceae Bacteria 1U7NJ@1239,29Q82@1,30B73@2,3F9YC@33958,4IHJU@91061 NA|NA|NA LEHHPAIP_01919 349123.Lreu23DRAFT_3119 3.7e-75 287.7 Bacteria ko:K03744 ko00000 Bacteria COG1704@1,COG1704@2 NA|NA|NA S LemA family LEHHPAIP_01920 349123.Lreu23DRAFT_3120 1.9e-58 232.6 Firmicutes Bacteria 1W0TM@1239,2CIF9@1,343GG@2 NA|NA|NA LEHHPAIP_01923 575594.ACOH01000003_gene795 1e-58 232.6 Lactobacillaceae Bacteria 1VCA6@1239,3F7MJ@33958,4HPP0@91061,COG1598@1,COG1598@2 NA|NA|NA S HicB_like antitoxin of bacterial toxin-antitoxin system LEHHPAIP_01924 1423814.HMPREF0549_1778 1.9e-55 222.2 Lactobacillaceae ps333 ko:K07474 ko00000 Bacteria 1VAD9@1239,3F6ZJ@33958,4HXMG@91061,COG3728@1,COG3728@2 NA|NA|NA L Terminase small subunit LEHHPAIP_01925 908339.HMPREF9265_1614 3.6e-187 661.0 Lactobacillaceae ps334 Bacteria 1TT2C@1239,3F3NN@33958,4H9S2@91061,COG1783@1,COG1783@2 NA|NA|NA S Terminase-like family LEHHPAIP_01926 908339.HMPREF9265_1613 3.1e-140 505.4 Lactobacillaceae Bacteria 1TR67@1239,2DB9U@1,2Z7Z6@2,3FB8U@33958,4HCTZ@91061 NA|NA|NA S Phage portal protein LEHHPAIP_01927 908339.HMPREF9265_1612 4.4e-61 242.7 Lactobacillaceae Bacteria 1UV98@1239,3FB8J@33958,4HSNW@91061,COG2369@1,COG2369@2 NA|NA|NA S Phage Mu protein F like protein LEHHPAIP_01929 908339.HMPREF9265_0944 4.9e-42 177.9 Lactobacillaceae Bacteria 1VEET@1239,2DNT1@1,32YZX@2,3F7QQ@33958,4HQ00@91061 NA|NA|NA S Domain of unknown function (DUF4355) LEHHPAIP_01930 1423775.BAMN01000027_gene69 6.7e-32 144.8 Lactobacillaceae Bacteria 1V4MS@1239,2CIG6@1,3042M@2,3F646@33958,4HHBB@91061 NA|NA|NA LEHHPAIP_01931 908339.HMPREF9265_0942 6.8e-31 140.2 Lactobacillaceae Bacteria 1VN9C@1239,2EKJJ@1,33E9D@2,3F7K9@33958,4HR20@91061 NA|NA|NA S Phage gp6-like head-tail connector protein LEHHPAIP_01932 908339.HMPREF9265_0941 7.3e-36 156.4 Lactobacillaceae Bacteria 1VIHK@1239,2E86K@1,332JW@2,3F8A2@33958,4HZJB@91061 NA|NA|NA LEHHPAIP_01933 908339.HMPREF9265_0940 2.4e-30 138.3 Lactobacillaceae Bacteria 1VFPA@1239,2CIV5@1,32ZS6@2,3F81G@33958,4HQWN@91061 NA|NA|NA S Bacteriophage HK97-gp10, putative tail-component LEHHPAIP_01934 908339.HMPREF9265_0939 2.5e-28 131.7 Lactobacillaceae Bacteria 1VEQW@1239,2DQ37@1,334JI@2,3FBQW@33958,4IS04@91061 NA|NA|NA S Protein of unknown function (DUF3168) LEHHPAIP_01935 908339.HMPREF9265_0938 7.2e-43 180.6 Lactobacillaceae Bacteria 1VUVY@1239,2F0XZ@1,33TZM@2,3F76N@33958,4HVU9@91061 NA|NA|NA S Phage tail tube protein LEHHPAIP_01936 349123.Lreu23DRAFT_4589 2e-205 721.5 Lactobacillaceae potA 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 iSB619.SA_RS05380 Bacteria 1TP2M@1239,3F40H@33958,4H9MS@91061,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system LEHHPAIP_01937 557436.Lreu_1645 4.5e-146 523.9 Lactobacillaceae potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1TQ7Z@1239,3F4CM@33958,4HAYS@91061,COG1176@1,COG1176@2 NA|NA|NA P ABC transporter permease LEHHPAIP_01938 557436.Lreu_1644 6.5e-140 503.4 Lactobacillaceae potC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSBO_1134.SBO_1939 Bacteria 1V0VD@1239,3F3ZN@33958,4H9ZC@91061,COG1177@1,COG1177@2 NA|NA|NA P ABC transporter permease LEHHPAIP_01939 557436.Lreu_1643 5.2e-206 723.4 Lactobacillaceae potD ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 1TPY1@1239,3F3W1@33958,4HAET@91061,COG0687@1,COG0687@2 NA|NA|NA P ABC transporter LEHHPAIP_01940 557436.Lreu_1642 2e-33 148.3 Lactobacillaceae Bacteria 1U73Z@1239,29PVV@1,30AU5@2,3F8XW@33958,4IGYF@91061 NA|NA|NA LEHHPAIP_01941 349123.Lreu23DRAFT_4585 5.8e-53 213.4 Lactobacillaceae Bacteria 1U73Z@1239,29PVV@1,30AU5@2,3F8XW@33958,4IGYF@91061 NA|NA|NA LEHHPAIP_01942 349123.Lreu23DRAFT_4584 2.2e-230 804.7 Lactobacillaceae ko:K08368 ko00000,ko02000 2.A.1 Bacteria 1UHPS@1239,3FBSX@33958,4HD28@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter LEHHPAIP_01943 349123.Lreu23DRAFT_4583 3e-254 884.0 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid LEHHPAIP_01944 349123.Lreu23DRAFT_4582 6.9e-74 283.1 Lactobacillaceae apfA 2.7.7.72,3.6.1.61 ko:K00974,ko:K18445 ko00230,ko03013,map00230,map03013 R00184,R09382,R09383,R09384,R09386 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1VED7@1239,3FBDM@33958,4HRPV@91061,COG1051@1,COG1051@2 NA|NA|NA F Nudix hydrolase LEHHPAIP_01945 557436.Lreu_1638 1.5e-98 365.5 Lactobacillaceae gmk2 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1VGNR@1239,3FBBC@33958,4HQMY@91061,COG0194@1,COG0194@2 NA|NA|NA F Guanylate kinase LEHHPAIP_01946 557436.Lreu_1637 2.1e-81 308.1 Lactobacillaceae zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711 ko00000,ko03000 Bacteria 1V6RI@1239,3F6W3@33958,4HIGM@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family LEHHPAIP_01947 557436.Lreu_1636 3.1e-17 95.1 Lactobacillaceae 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 R01206,R02334 RC00467 ko00000,ko00001,ko01000 GH18 Bacteria 1VN2E@1239,2EQI3@1,33I43@2,3F860@33958,4HR4S@91061 NA|NA|NA LEHHPAIP_01948 349123.Lreu23DRAFT_4578 1e-148 532.7 Lactobacillaceae Bacteria 1V7ET@1239,2C6F0@1,32RH8@2,3F4UC@33958,4HJDI@91061 NA|NA|NA LEHHPAIP_01949 557436.Lreu_1634 3.4e-39 167.2 Bacteria pspC ko:K03973 ko00000,ko02048,ko03000 Bacteria COG1983@1,COG1983@2 NA|NA|NA KT positive regulation of macromolecule biosynthetic process LEHHPAIP_01950 349123.Lreu23DRAFT_4575 7.8e-94 349.7 Lactobacillaceae Bacteria 1VEM5@1239,3F66Z@33958,4HQRV@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator (TetR family) LEHHPAIP_01951 557436.Lreu_1632 5.3e-221 774.6 Lactobacillaceae ko:K01421 ko00000 Bacteria 1TQ15@1239,3F3Y3@33958,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein LEHHPAIP_01952 349123.Lreu23DRAFT_4572 2.1e-180 638.3 Lactobacillaceae 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family LEHHPAIP_01954 349123.Lreu23DRAFT_4570 6.6e-35 152.9 Lactobacillaceae Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein LEHHPAIP_01955 557436.Lreu_1628 8.6e-232 809.3 Lactobacillaceae hflX ko:K03665 ko00000,ko03009 Bacteria 1TNZB@1239,3F4B2@33958,4HACA@91061,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis LEHHPAIP_01956 557436.Lreu_1627 5e-127 460.3 Lactobacillaceae 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQWQ@1239,3F5CT@33958,4HFDZ@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase LEHHPAIP_01957 557436.Lreu_1626 2e-115 421.8 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F51Q@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein LEHHPAIP_01958 557436.Lreu_1625 0.0 1506.5 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase LEHHPAIP_01959 557436.Lreu_1622 1.3e-36 158.7 Bacteria Bacteria COG0446@1,COG0446@2 NA|NA|NA Q pyridine nucleotide-disulphide oxidoreductase LEHHPAIP_01960 557436.Lreu_1621 4.7e-157 560.5 Lactobacillaceae Bacteria 1TPUW@1239,3F5JP@33958,4HDIE@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family LEHHPAIP_01961 557436.Lreu_1620 0.0 1372.8 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily LEHHPAIP_01962 349123.Lreu23DRAFT_4561 1.7e-176 625.2 Lactobacillaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,3F42Q@33958,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase LEHHPAIP_01963 349123.Lreu23DRAFT_4560 1.7e-218 765.0 Lactobacillaceae ko:K07133 ko00000 Bacteria 1TP7X@1239,3F51K@33958,4HCSJ@91061,COG1373@1,COG1373@2 NA|NA|NA S cog cog1373 LEHHPAIP_01965 349123.Lreu23DRAFT_4559 3.6e-301 1040.0 Lactobacillaceae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iLJ478.TM1820 Bacteria 1TPG8@1239,3F3NV@33958,4HA7Q@91061,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP LEHHPAIP_01966 557436.Lreu_1774 8.2e-85 320.9 Lactobacillaceae tra ko:K07482 ko00000 Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family LEHHPAIP_01968 1423814.HMPREF0549_1566 2.4e-260 904.4 Lactobacillaceae mco Bacteria 1TQSU@1239,3F3XB@33958,4HDD6@91061,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase LEHHPAIP_01970 1423814.HMPREF0549_1093 8.4e-189 666.4 Lactobacillaceae Bacteria 1TQHD@1239,3FB93@33958,4HBCZ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_01971 525309.HMPREF0494_0484 8.2e-70 269.6 Lactobacillaceae Bacteria 1V43K@1239,3F6PX@33958,4HH01@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family LEHHPAIP_01972 557436.Lreu_0631 2.8e-207 727.6 Lactobacillaceae pdhA 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TQDG@1239,3F3JK@33958,4H9PQ@91061,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component LEHHPAIP_01973 349123.Lreu23DRAFT_3683 2.4e-181 641.3 Lactobacillaceae pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2496c,iYO844.BSU14590 Bacteria 1TP3J@1239,3F4RV@33958,4HA4H@91061,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, C-terminal domain protein LEHHPAIP_01974 557436.Lreu_0633 1.7e-222 778.5 Lactobacillaceae pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TR5N@1239,3F3RR@33958,4HA7A@91061,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex LEHHPAIP_01975 557436.Lreu_0634 1.4e-275 954.9 Lactobacillaceae lpdA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 Bacteria 1TP1W@1239,3F426@33958,4HB3K@91061,COG1249@1,COG1249@2 NA|NA|NA C Dehydrogenase LEHHPAIP_01976 557436.Lreu_0635 3.7e-45 187.2 Lactobacillaceae yktA ko:K16509 ko00000 Bacteria 1VEK8@1239,3F80A@33958,4HNKR@91061,COG4476@1,COG4476@2 NA|NA|NA S Belongs to the UPF0223 family LEHHPAIP_01977 349123.Lreu23DRAFT_3687 3.8e-134 484.2 Lactobacillaceae suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4E@1239,3F5BB@33958,4HB92@91061,COG0483@1,COG0483@2 NA|NA|NA G Belongs to the inositol monophosphatase superfamily LEHHPAIP_01978 557436.Lreu_0637 0.0 1209.5 Lactobacillaceae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1TQ5Y@1239,3F3UK@33958,4HAQ6@91061,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA LEHHPAIP_01979 557436.Lreu_0638 2.7e-222 777.7 Lactobacillaceae ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1TPT7@1239,3F4IK@33958,4HAEV@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family LEHHPAIP_01980 349123.Lreu23DRAFT_3690 3e-44 184.1 Lactobacillaceae ylbG Bacteria 1U6H3@1239,3F7WV@33958,4IG9C@91061,COG4471@1,COG4471@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2129) LEHHPAIP_01981 557436.Lreu_0640 1.6e-97 362.1 Lactobacillaceae rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JF@1239,3F505@33958,4HGXT@91061,COG0742@1,COG0742@2 NA|NA|NA L RNA methyltransferase, RsmD family LEHHPAIP_01982 557436.Lreu_0641 8.7e-90 336.3 Lactobacillaceae coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016043,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 1V3MR@1239,3F6YS@33958,4HH47@91061,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate LEHHPAIP_01983 349123.Lreu23DRAFT_3693 1.8e-195 688.3 Lactobacillaceae ylbL ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 1TRUF@1239,3F4KY@33958,4HBAY@91061,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family LEHHPAIP_01984 349123.Lreu23DRAFT_3694 5.8e-80 303.9 Lactobacillaceae comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1VA3W@1239,3F7NP@33958,4HKJ1@91061,COG1555@1,COG1555@2 NA|NA|NA L Competence protein ComEA LEHHPAIP_01985 349123.Lreu23DRAFT_3695 3.1e-89 334.3 Lactobacillaceae comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1V3PU@1239,3F6BF@33958,4HCDG@91061,COG2131@1,COG2131@2 NA|NA|NA F ComE operon protein 2 LEHHPAIP_01986 557436.Lreu_0645 0.0 1373.6 Lactobacillaceae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1TS9U@1239,3F3VT@33958,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein ComEC LEHHPAIP_01987 557436.Lreu_0646 3.1e-147 528.1 Lactobacillaceae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRM0@1239,3F3TP@33958,4HBB4@91061,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit LEHHPAIP_01988 349123.Lreu23DRAFT_3698 5.1e-35 153.3 Lactobacillaceae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGX@1239,3F7D8@33958,4HNJS@91061,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA LEHHPAIP_01989 349123.Lreu23DRAFT_3699 1.6e-42 178.3 Lactobacillaceae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,3F7DV@33958,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome LEHHPAIP_01990 557436.Lreu_0649 0.0 1148.3 Lactobacillaceae rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3U9@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay LEHHPAIP_01991 349123.Lreu23DRAFT_3701 1.6e-163 582.0 Lactobacillaceae Bacteria 1VXFK@1239,3FBB5@33958,4HX6X@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat LEHHPAIP_01992 349123.Lreu23DRAFT_3702 3.8e-226 790.4 Lactobacillaceae tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPKC@1239,3F3ZP@33958,4HAEH@91061,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis LEHHPAIP_01993 349123.Lreu23DRAFT_3703 1.1e-237 828.9 Lactobacillaceae tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 1TQQ8@1239,3F40B@33958,4H9Q8@91061,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase LEHHPAIP_01994 349123.Lreu23DRAFT_3704 1.8e-234 818.1 Lactobacillaceae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1TQ00@1239,3F41K@33958,4H9U4@91061,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP LEHHPAIP_01995 557436.Lreu_0654 3.6e-108 397.5 Lactobacillaceae engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1TSPW@1239,3F44G@33958,4HBXZ@91061,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation LEHHPAIP_01996 349123.Lreu23DRAFT_3706 6.1e-60 236.5 Lactobacillaceae MA20_27270 Bacteria 1VIQA@1239,3F6WJ@33958,4HM6C@91061,COG1694@1,COG1694@2 NA|NA|NA S mazG nucleotide pyrophosphohydrolase LEHHPAIP_01997 349123.Lreu23DRAFT_3708 4.9e-08 62.8 Lactobacillaceae Bacteria 1U6ZK@1239,29PSD@1,30AQK@2,3F8RX@33958,4IGTV@91061 NA|NA|NA LEHHPAIP_01998 349123.Lreu23DRAFT_3709 0.0 1200.3 Lactobacillaceae uvrC ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP4B@1239,3F3MY@33958,4H9QH@91061,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision LEHHPAIP_01999 557436.Lreu_0658 9.7e-247 859.0 Lactobacillaceae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1TPX7@1239,3F4ZA@33958,4H9P8@91061,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control LEHHPAIP_02000 557436.Lreu_0659 4.9e-176 623.6 Lactobacillaceae rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TRGP@1239,3F4F1@33958,4HABM@91061,COG1234@1,COG1234@2 NA|NA|NA J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA LEHHPAIP_02001 557436.Lreu_0660 2.1e-154 551.6 Lactobacillaceae XK27_05435 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1UG37@1239,3FC9N@33958,4HC7Y@91061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family LEHHPAIP_02002 349123.Lreu23DRAFT_3713 0.0 1469.1 Lactobacillaceae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXE@1239,3F42C@33958,4H9UP@91061,COG0608@1,COG0608@2 NA|NA|NA L Single-stranded-DNA-specific exonuclease RecJ LEHHPAIP_02003 349123.Lreu23DRAFT_3714 2.7e-91 341.3 Lactobacillaceae apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 1V1BV@1239,3F4DB@33958,4HFUA@91061,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis LEHHPAIP_02004 349123.Lreu23DRAFT_3715 4.8e-87 327.4 Lactobacillaceae Bacteria 1W3AZ@1239,28UQM@1,2ZGUY@2,3F65Q@33958,4I0YM@91061 NA|NA|NA LEHHPAIP_02006 557436.Lreu_0675 1e-127 462.6 Lactobacillaceae rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469,ko:K06993 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V4A0@1239,3F3RG@33958,4HHJ9@91061,COG0328@1,COG0328@2,COG3341@1,COG3341@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids LEHHPAIP_02007 349123.Lreu23DRAFT_3717 2.4e-209 734.6 Lactobacillaceae mvaS 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4K@1239,3F425@33958,4HA67@91061,COG3425@1,COG3425@2 NA|NA|NA I Hydroxymethylglutaryl-CoA synthase LEHHPAIP_02008 349123.Lreu23DRAFT_3719 5.5e-115 420.2 Lactobacillaceae lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1TQ3H@1239,3F3JG@33958,4HBHA@91061,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair LEHHPAIP_02009 557436.Lreu_0678 1.3e-35 155.2 Lactobacillaceae ynzC Bacteria 1VEKJ@1239,3F87S@33958,4HNIB@91061,COG4224@1,COG4224@2 NA|NA|NA S UPF0291 protein LEHHPAIP_02010 349123.Lreu23DRAFT_3721 9.8e-30 135.6 Lactobacillaceae yneF ko:K09976 ko00000 Bacteria 1VEJC@1239,3F809@33958,4HKMJ@91061,COG3763@1,COG3763@2 NA|NA|NA S Uncharacterised protein family (UPF0154) LEHHPAIP_02011 557436.Lreu_0680 4.6e-117 427.2 Lactobacillaceae plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1U8N2@1239,3F4QB@33958,4HDQR@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase LEHHPAIP_02012 557436.Lreu_0681 2.7e-140 504.6 Lactobacillaceae yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 ko00000,ko01000,ko03016 Bacteria 1TQ25@1239,3F4C5@33958,4HA8W@91061,COG4123@1,COG4123@2 NA|NA|NA L Methyltransferase small domain LEHHPAIP_02013 349123.Lreu23DRAFT_3724 7.1e-49 199.5 Lactobacillaceae yazA ko:K07461 ko00000 Bacteria 1VEZF@1239,3F7G2@33958,4HNHJ@91061,COG2827@1,COG2827@2 NA|NA|NA L GIY-YIG catalytic domain protein LEHHPAIP_02014 557436.Lreu_0683 7e-181 639.8 Lactobacillaceae ldhD 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family LEHHPAIP_02015 349123.Lreu23DRAFT_3726 4.6e-143 513.8 Lactobacillaceae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPNA@1239,3F3M1@33958,4H9N5@91061,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family LEHHPAIP_02016 349123.Lreu23DRAFT_3727 9.3e-153 546.2 Lactobacillaceae tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1TPFJ@1239,3F459@33958,4HBDV@91061,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome LEHHPAIP_02017 349123.Lreu23DRAFT_3728 8.2e-129 466.5 Lactobacillaceae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1TPXN@1239,3F42J@33958,4H9UB@91061,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP LEHHPAIP_02018 349123.Lreu23DRAFT_3729 1.4e-93 349.0 Lactobacillaceae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1V1F2@1239,3F4X2@33958,4HFSH@91061,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another LEHHPAIP_02019 557436.Lreu_0690 2.4e-141 508.1 Lactobacillaceae uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1TQTS@1239,3F42M@33958,4HA37@91061,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids LEHHPAIP_02020 349123.Lreu23DRAFT_3002 5.8e-138 496.9 Lactobacillaceae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 1UPNB@1239,3F4AF@33958,4IV81@91061,COG0575@1,COG0575@2 NA|NA|NA I Belongs to the CDS family LEHHPAIP_02021 557436.Lreu_0692 3.7e-235 820.5 Lactobacillaceae rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399,ko:K11749,ko:K16922 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPMC@1239,3F3TM@33958,4HAQ5@91061,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease LEHHPAIP_02022 557436.Lreu_0693 0.0 1128.6 Lactobacillaceae proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1TRBV@1239,3F44A@33958,4H9NN@91061,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS LEHHPAIP_02023 349123.Lreu23DRAFT_3005 0.0 2887.1 Lactobacillaceae polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPAG@1239,3F4AN@33958,4H9RF@91061,COG2176@1,COG2176@2 NA|NA|NA L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity LEHHPAIP_02024 349123.Lreu23DRAFT_3006 9.4e-83 312.8 Lactobacillaceae rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1V6KT@1239,3F6GZ@33958,4HH88@91061,COG0779@1,COG0779@2 NA|NA|NA J Required for maturation of 30S ribosomal subunits LEHHPAIP_02025 557436.Lreu_0696 2.3e-215 754.6 Lactobacillaceae nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600,ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021 Bacteria 1TPB3@1239,3F3KZ@33958,4HA7F@91061,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination LEHHPAIP_02026 349123.Lreu23DRAFT_3008 1e-44 185.7 Lactobacillaceae ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria 1VEJS@1239,3F7E2@33958,4HKBY@91061,COG2740@1,COG2740@2 NA|NA|NA K Protein of unknown function (DUF448) LEHHPAIP_02027 349123.Lreu23DRAFT_3009 1.3e-48 198.7 Lactobacillaceae ylxQ ko:K07590,ko:K07742 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEYG@1239,3F7ZK@33958,4HNY7@91061,COG1358@1,COG1358@2 NA|NA|NA J ribosomal protein LEHHPAIP_02028 557436.Lreu_0699 0.0 1232.6 Lactobacillaceae infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1TPAI@1239,3F3JV@33958,4HA8S@91061,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex LEHHPAIP_02029 349123.Lreu23DRAFT_3011 2.1e-58 231.5 Lactobacillaceae rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1VA0P@1239,3F6WZ@33958,4HII1@91061,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA LEHHPAIP_02030 557436.Lreu_0701 7.1e-164 583.2 Lactobacillaceae truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 ko00000,ko01000,ko03000,ko03016 iSB619.SA_RS06305 Bacteria 1TP9Y@1239,3F3NX@33958,4HA9X@91061,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs LEHHPAIP_02031 349123.Lreu23DRAFT_3013 4.5e-177 627.1 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1TPKS@1239,3F3TG@33958,4H9KE@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family LEHHPAIP_02032 557436.Lreu_0703 2.9e-63 247.7 Lactobacillaceae Bacteria 1U6DW@1239,2A5X0@1,30UP0@2,3F7P8@33958,4IG5K@91061 NA|NA|NA LEHHPAIP_02033 349123.Lreu23DRAFT_3015 1e-193 682.6 Lactobacillaceae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1TQP7@1239,3F3ST@33958,4HAX5@91061,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons LEHHPAIP_02034 557436.Lreu_0705 3.9e-75 287.7 Lactobacillaceae grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1V6G2@1239,3F4DY@33958,4HIRK@91061,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ LEHHPAIP_02035 557436.Lreu_0706 0.0 1128.6 Lactobacillaceae dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TP1J@1239,3F48C@33958,4HA9S@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein LEHHPAIP_02036 349123.Lreu23DRAFT_3018 2.5e-198 698.0 Lactobacillaceae dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 1TP00@1239,3F490@33958,4H9KA@91061,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins LEHHPAIP_02037 349123.Lreu23DRAFT_3019 0.0 1192.2 Lactobacillaceae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1TP0G@1239,3F3Z1@33958,4HASA@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner LEHHPAIP_02038 349123.Lreu23DRAFT_3020 2e-274 951.0 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase LEHHPAIP_02039 557436.Lreu_0715 1.1e-198 699.1 Lactobacillaceae mdh 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 R02935,R02936 RC00169 ko00000,ko00001,ko01000 Bacteria 1TR0Z@1239,3F4JZ@33958,4HB6X@91061,COG2055@1,COG2055@2 NA|NA|NA C Belongs to the LDH2 MDH2 oxidoreductase family LEHHPAIP_02041 349123.Lreu23DRAFT_3022 5.7e-172 610.1 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family LEHHPAIP_02042 557436.Lreu_0717 7.5e-58 229.6 Lactobacillaceae Bacteria 1W026@1239,2FCQV@1,344U2@2,3F7FM@33958,4HZ7F@91061 NA|NA|NA LEHHPAIP_02043 557436.Lreu_0718 3.1e-178 630.9 Lactobacillaceae prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1TPKI@1239,3F47Z@33958,4HAMF@91061,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase LEHHPAIP_02044 349123.Lreu23DRAFT_3025 6.7e-128 463.4 Lactobacillaceae rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1V1CT@1239,3F64Z@33958,4HH8P@91061,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit LEHHPAIP_02045 557436.Lreu_0720 9.4e-50 202.6 Lactobacillaceae Bacteria 1U6RR@1239,2C2I6@1,30AJ5@2,3F8DM@33958,4IGJ7@91061 NA|NA|NA LEHHPAIP_02046 349123.Lreu23DRAFT_3027 0.0 1476.1 Lactobacillaceae relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 iHN637.CLJU_RS16615,iYO844.BSU27600 Bacteria 1TNYZ@1239,3F44F@33958,4HBX7@91061,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance LEHHPAIP_02047 349123.Lreu23DRAFT_3028 8.4e-78 296.2 Lactobacillaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,3F6GK@33958,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality LEHHPAIP_02048 349123.Lreu23DRAFT_3039 9.3e-166 589.3 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U79A@1239,3F3RK@33958,4HAZS@91061,COG3001@1,COG3001@2 NA|NA|NA G Phosphotransferase enzyme family LEHHPAIP_02049 349123.Lreu23DRAFT_3040 0.0 1214.5 Lactobacillaceae aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,3F4PE@33958,4HACD@91061,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) LEHHPAIP_02050 349123.Lreu23DRAFT_3041 1e-131 476.1 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein LEHHPAIP_02051 349123.Lreu23DRAFT_3042 1.1e-262 912.1 Lactobacillaceae glnPH2 ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease LEHHPAIP_02052 349123.Lreu23DRAFT_3043 1.2e-23 115.2 Lactobacillaceae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEHU@1239,3F81Y@33958,4HNPV@91061,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family LEHHPAIP_02053 349123.Lreu23DRAFT_3044 8.6e-70 269.6 Lactobacillaceae yqeY ko:K09117 ko00000 Bacteria 1V6F2@1239,3F6I0@33958,4HIQP@91061,COG1610@1,COG1610@2 NA|NA|NA S YqeY-like protein LEHHPAIP_02054 557436.Lreu_0730 1.4e-186 658.7 Lactobacillaceae cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein LEHHPAIP_02055 349123.Lreu23DRAFT_3047 1.7e-237 828.2 Lactobacillaceae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1TP3X@1239,3F46X@33958,4HA1E@91061,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily LEHHPAIP_02056 349123.Lreu23DRAFT_3048 3.5e-263 913.7 Lactobacillaceae argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TNZ6@1239,3F4PF@33958,4HB24@91061,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase LEHHPAIP_02057 557436.Lreu_0733 3.8e-83 314.3 Lactobacillaceae bioY GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1VAAD@1239,3F6YG@33958,4HI8T@91061,COG1268@1,COG1268@2 NA|NA|NA S BioY family LEHHPAIP_02058 557436.Lreu_0734 1.4e-170 605.5 Lactobacillaceae birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524,ko:K04096 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2,COG1654@1,COG1654@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor LEHHPAIP_02059 557436.Lreu_0735 4.5e-183 647.1 Lactobacillaceae phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1TP35@1239,3F4E7@33958,4HBD5@91061,COG1702@1,COG1702@2 NA|NA|NA T phosphate starvation-inducible protein PhoH LEHHPAIP_02060 349123.Lreu23DRAFT_3052 1.2e-82 312.4 Lactobacillaceae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1V6BU@1239,3F516@33958,4HIIE@91061,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA LEHHPAIP_02061 349123.Lreu23DRAFT_3053 2.1e-59 235.0 Lactobacillaceae dgkA 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2369,iSB619.SA_RS07900 Bacteria 1VEGR@1239,3F7DC@33958,4HNKN@91061,COG0818@1,COG0818@2 NA|NA|NA M Diacylglycerol kinase LEHHPAIP_02062 557436.Lreu_0738 3.6e-168 597.4 Lactobacillaceae era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1TP3R@1239,3F3WQ@33958,4H9WF@91061,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism LEHHPAIP_02063 349123.Lreu23DRAFT_3055 5.8e-146 523.5 Lactobacillaceae recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,3F56P@33958,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination LEHHPAIP_02064 349123.Lreu23DRAFT_3056 2.9e-179 634.4 Lactobacillaceae glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1TPW8@1239,3F3T8@33958,4HBCF@91061,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit LEHHPAIP_02065 557436.Lreu_0741 0.0 1349.0 Lactobacillaceae glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1TNZ7@1239,3F4G8@33958,4H9NT@91061,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit LEHHPAIP_02066 557436.Lreu_0742 0.0 1206.0 Lactobacillaceae dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQ0X@1239,3F3N1@33958,4HAG2@91061,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication LEHHPAIP_02067 557436.Lreu_0743 2.9e-207 727.6 Lactobacillaceae sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,3F4CF@33958,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth LEHHPAIP_02068 349123.Lreu23DRAFT_3060 2.4e-220 771.2 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase LEHHPAIP_02069 557436.Lreu_0746 4.7e-123 447.2 Lactobacillaceae trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 ko00000,ko01000,ko03016 Bacteria 1V3I4@1239,3F4GT@33958,4HHIM@91061,COG2384@1,COG2384@2 NA|NA|NA S SAM-dependent methyltransferase LEHHPAIP_02070 557436.Lreu_0747 8.5e-156 556.2 Lactobacillaceae yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ27@1239,3F3ZD@33958,4H9NY@91061,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family LEHHPAIP_02071 557436.Lreu_0748 6.6e-237 826.2 Lactobacillaceae pepT GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides LEHHPAIP_02072 557436.Lreu_0749 2e-29 134.4 Lactobacillaceae Bacteria 1U6MS@1239,2DKRG@1,30AGI@2,3F85T@33958,4IGEJ@91061 NA|NA|NA S Protein of unknown function (DUF2929) LEHHPAIP_02073 557436.Lreu_0750 0.0 2140.2 Lactobacillaceae dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPYG@1239,3F4AM@33958,4H9T3@91061,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase LEHHPAIP_02074 349123.Lreu23DRAFT_3066 1.4e-270 938.3 Lactobacillaceae pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 1TPGG@1239,3F3JU@33958,4H9VY@91061,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family LEHHPAIP_02075 349123.Lreu23DRAFT_3067 3.5e-168 597.4 Lactobacillaceae cvfB ko:K00243 ko00000 Bacteria 1TQ1Z@1239,3F44W@33958,4HDAZ@91061,COG2996@1,COG2996@2 NA|NA|NA S S1 domain LEHHPAIP_02076 349123.Lreu23DRAFT_3068 9.1e-164 582.8 Lactobacillaceae xerD ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3F3V9@33958,4HAEX@91061,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD LEHHPAIP_02077 557436.Lreu_0754 2.8e-63 247.7 Lactobacillaceae ribT ko:K02859 ko00000 Bacteria 1VAD7@1239,3F7QC@33958,4HKR2@91061,COG0454@1,COG0456@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases LEHHPAIP_02078 349123.Lreu23DRAFT_3070 2.5e-136 491.5 Lactobacillaceae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1TRW3@1239,3F4FS@33958,4HA6Q@91061,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves LEHHPAIP_02079 349123.Lreu23DRAFT_3071 1.7e-105 388.7 Lactobacillaceae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1V6HI@1239,3F5RN@33958,4HIQ0@91061,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves LEHHPAIP_02080 349123.Lreu23DRAFT_3072 5.9e-129 466.8 Lactobacillaceae rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,3F402@33958,4H9MU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family LEHHPAIP_02081 349123.Lreu23DRAFT_3179 6e-100 370.2 Lactobacillaceae Bacteria 1V4BW@1239,3F4HD@33958,4HHFT@91061,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins LEHHPAIP_02082 557436.Lreu_0759 3.3e-194 684.1 Lactobacillaceae ypbB 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU9@1239,3F45N@33958,4HJ71@91061,COG4955@1,COG4955@2 NA|NA|NA S Helix-turn-helix domain LEHHPAIP_02083 557436.Lreu_0760 1.4e-267 928.3 Lactobacillaceae recQ1 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ LEHHPAIP_02084 349123.Lreu23DRAFT_3182 2.5e-13 82.4 Lactobacillaceae Bacteria 1VFEU@1239,3F6WV@33958,4HNW5@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif LEHHPAIP_02085 349123.Lreu23DRAFT_3183 3.8e-117 427.6 Lactobacillaceae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1V3IA@1239,3F3W4@33958,4HFZE@91061,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily LEHHPAIP_02086 349123.Lreu23DRAFT_3184 1.4e-205 722.2 Lactobacillaceae rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1TQ9N@1239,3F4DQ@33958,4H9PX@91061,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 LEHHPAIP_02087 349123.Lreu23DRAFT_3185 9.4e-250 869.0 Lactobacillaceae der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 1TPNM@1239,3F4V0@33958,4HAJ6@91061,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis LEHHPAIP_02088 349123.Lreu23DRAFT_3186 2.6e-40 171.0 Lactobacillaceae hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1V9XQ@1239,3F6YN@33958,4HKF2@91061,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions LEHHPAIP_02089 557436.Lreu_0766 1.4e-234 818.5 Lactobacillaceae Bacteria 1TT97@1239,3F3ND@33958,4HAIA@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat protein LEHHPAIP_02090 349123.Lreu23DRAFT_3188 4.5e-222 776.9 Lactobacillaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1TQ2A@1239,3F3VH@33958,4HB2W@91061,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate LEHHPAIP_02091 349123.Lreu23DRAFT_3189 0.0 1188.3 Lactobacillaceae yfmR ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 1TPAX@1239,3FC7W@33958,4H9TK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein LEHHPAIP_02092 557436.Lreu_0769 7.2e-191 672.9 Lactobacillaceae thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSIR@1239,3F3SB@33958,4H9QS@91061,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis LEHHPAIP_02093 349123.Lreu23DRAFT_3191 1.6e-90 338.6 Lactobacillaceae folA 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 Bacteria 1VB80@1239,3F6Y4@33958,4HIGJ@91061,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis LEHHPAIP_02094 349123.Lreu23DRAFT_3192 1.3e-111 409.1 Lactobacillaceae hlyIII ko:K11068 ko00000,ko02042 Bacteria 1TSFK@1239,3F578@33958,4HAT2@91061,COG1272@1,COG1272@2 NA|NA|NA S protein, hemolysin III LEHHPAIP_02095 349123.Lreu23DRAFT_3193 6.4e-151 540.0 Lactobacillaceae DegV Bacteria 1TRZ4@1239,3F4CW@33958,4HBR8@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family LEHHPAIP_02096 557436.Lreu_0773 1.8e-167 595.1 Lactobacillaceae ypmR GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 Bacteria 1V76B@1239,3FBFD@33958,4HGIN@91061,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family LEHHPAIP_02097 557436.Lreu_0774 8.2e-108 396.4 Lactobacillaceae ypmS Bacteria 1VF0K@1239,3F5K5@33958,4HIYN@91061,COG4698@1,COG4698@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2140) LEHHPAIP_02098 349123.Lreu23DRAFT_3196 8.4e-34 149.1 Lactobacillaceae yozE Bacteria 1VFI4@1239,3FCDP@33958,4HR7P@91061,COG4479@1,COG4479@2 NA|NA|NA S Belongs to the UPF0346 family LEHHPAIP_02099 349123.Lreu23DRAFT_3197 5.4e-161 573.5 Lactobacillaceae ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1TQGK@1239,3F3MI@33958,4HA4D@91061,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity LEHHPAIP_02100 557436.Lreu_0777 2.1e-140 505.0 Lactobacillaceae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V1D6@1239,3F3JC@33958,4HB7M@91061,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids LEHHPAIP_02101 557436.Lreu_0778 3.3e-118 431.0 Lactobacillaceae dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1TPP7@1239,3F41U@33958,4HGWM@91061,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA LEHHPAIP_02102 575594.ACOH01000003_gene837 1e-95 357.1 Lactobacillaceae Bacteria 1TTJI@1239,3F4IB@33958,4HDG6@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_02104 911104.AEKT01000044_gene1032 1.9e-19 103.2 Leuconostocaceae Bacteria 1VZ38@1239,29Q09@1,345NW@2,4AYPA@81850,4HYJY@91061 NA|NA|NA LEHHPAIP_02105 557436.Lreu_0800 6.8e-39 166.8 Lactobacillaceae Bacteria 1W2T9@1239,29QK8@1,30BJU@2,3FAPG@33958,4I1HD@91061 NA|NA|NA S Pfam:DUF955 LEHHPAIP_02106 324831.LGAS_0575 9.3e-21 106.3 Lactobacillaceae xre Bacteria 1VK84@1239,3F85V@33958,4HRBT@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain LEHHPAIP_02116 1423767.BALU01000006_gene801 5.6e-34 151.4 Lactobacillaceae Bacteria 1V7VV@1239,2B9XI@1,323AV@2,3FABF@33958,4HK2T@91061 NA|NA|NA S Protein of unknown function (DUF1071) LEHHPAIP_02117 575594.ACOH01000003_gene814 7.4e-73 280.4 Lactobacillaceae Bacteria 1VBY4@1239,2CV27@1,32SWP@2,3FBAM@33958,4HKQV@91061 NA|NA|NA S Putative HNHc nuclease LEHHPAIP_02118 1298920.KI911353_gene4869 1.9e-21 109.0 Lachnoclostridium ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,21ZZF@1506553,24HF9@186801,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein LEHHPAIP_02120 1423814.HMPREF0549_1765 5.2e-28 131.7 Lactobacillaceae Bacteria 1UIKU@1239,3F83K@33958,4ISMR@91061,COG1846@1,COG1846@2 NA|NA|NA K Conserved phage C-terminus (Phg_2220_C) LEHHPAIP_02121 1423732.BALS01000105_gene422 5.7e-40 171.4 Lactobacillaceae dnaC 3.4.21.53 ko:K02315,ko:K04076 ko00000,ko01000,ko01002,ko03032 Bacteria 1V36Z@1239,3F6VF@33958,4HXKM@91061,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein LEHHPAIP_02125 575594.ACOH01000003_gene808 1.9e-52 212.2 Lactobacillaceae Bacteria 1VW9P@1239,2DM3A@1,31IKE@2,3F7X0@33958,4HWSR@91061 NA|NA|NA S Protein of unknown function (DUF1064) LEHHPAIP_02126 349123.Lreu23DRAFT_3891 2.3e-184 651.4 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_02127 349123.Lreu23DRAFT_3890 2.2e-122 444.9 Lactobacillaceae 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1V65N@1239,3F6P9@33958,4HHB0@91061,COG0286@1,COG0286@2 NA|NA|NA V site-specific DNA-methyltransferase (adenine-specific) activity LEHHPAIP_02128 349123.Lreu23DRAFT_4013 1.2e-14 84.7 Lactobacillaceae Bacteria 1U8FD@1239,2AYWW@1,31R2K@2,3FAX9@33958,4IID9@91061 NA|NA|NA LEHHPAIP_02133 349123.Lreu23DRAFT_3098 2.1e-18 98.2 Lactobacillaceae Bacteria 1W3JH@1239,29C1X@1,2ZZ0E@2,3F8BR@33958,4I1E9@91061 NA|NA|NA LEHHPAIP_02135 349123.Lreu23DRAFT_3879 1.1e-14 86.7 Bacilli arpU Bacteria 1W30Q@1239,2DPRG@1,3333C@2,4I13H@91061 NA|NA|NA S Phage transcriptional regulator, ArpU family LEHHPAIP_02137 1416334.X2CXX2_9CAUD 1.7e-55 222.6 Myoviridae Viruses 4QBNM@10239,4QII1@10662,4QPQ9@28883,4QUT2@35237 NA|NA|NA S N-methyltransferase activity LEHHPAIP_02138 508419.F8J156_9CAUD 4.3e-38 165.2 Siphoviridae Viruses 4QCFZ@10239,4QMFF@10699,4QRJS@28883,4QVRS@35237 NA|NA|NA LEHHPAIP_02139 1423724.BAMM01000023_gene1916 6.3e-42 177.2 Lactobacillaceae Bacteria 1V6XW@1239,3F7DT@33958,4HIUS@91061,COG2963@1,COG2963@2 NA|NA|NA L transposase activity LEHHPAIP_02140 908339.HMPREF9265_1614 4.9e-192 677.2 Lactobacillaceae ps334 Bacteria 1TT2C@1239,3F3NN@33958,4H9S2@91061,COG1783@1,COG1783@2 NA|NA|NA S Terminase-like family LEHHPAIP_02141 908339.HMPREF9265_1613 1.2e-139 503.4 Lactobacillaceae Bacteria 1TR67@1239,2DB9U@1,2Z7Z6@2,3FB8U@33958,4HCTZ@91061 NA|NA|NA S Phage portal protein LEHHPAIP_02142 908339.HMPREF9265_1612 2e-85 322.4 Lactobacillaceae Bacteria 1UV98@1239,3FB8J@33958,4HSNW@91061,COG2369@1,COG2369@2 NA|NA|NA S Phage Mu protein F like protein LEHHPAIP_02143 1206110.L0P6F5_9CAUD 1e-25 123.2 Myoviridae Viruses 4QAIU@10239,4QI6J@10662,4QPDE@28883,4QUQC@35237 NA|NA|NA S sequence-specific DNA binding transcription factor activity LEHHPAIP_02144 908339.HMPREF9265_0944 2.5e-41 175.6 Lactobacillaceae Bacteria 1VEET@1239,2DNT1@1,32YZX@2,3F7QQ@33958,4HQ00@91061 NA|NA|NA S Domain of unknown function (DUF4355) LEHHPAIP_02145 1423775.BAMN01000027_gene69 6.7e-32 144.8 Lactobacillaceae Bacteria 1V4MS@1239,2CIG6@1,3042M@2,3F646@33958,4HHBB@91061 NA|NA|NA LEHHPAIP_02146 908339.HMPREF9265_0942 6.8e-31 140.2 Lactobacillaceae Bacteria 1VN9C@1239,2EKJJ@1,33E9D@2,3F7K9@33958,4HR20@91061 NA|NA|NA S Phage gp6-like head-tail connector protein LEHHPAIP_02147 908339.HMPREF9265_0941 7.3e-36 156.4 Lactobacillaceae Bacteria 1VIHK@1239,2E86K@1,332JW@2,3F8A2@33958,4HZJB@91061 NA|NA|NA LEHHPAIP_02148 908339.HMPREF9265_0940 2.4e-30 138.3 Lactobacillaceae Bacteria 1VFPA@1239,2CIV5@1,32ZS6@2,3F81G@33958,4HQWN@91061 NA|NA|NA S Bacteriophage HK97-gp10, putative tail-component LEHHPAIP_02149 908339.HMPREF9265_0939 2.5e-28 131.7 Lactobacillaceae Bacteria 1VEQW@1239,2DQ37@1,334JI@2,3FBQW@33958,4IS04@91061 NA|NA|NA S Protein of unknown function (DUF3168) LEHHPAIP_02150 908339.HMPREF9265_0938 7.2e-43 180.6 Lactobacillaceae Bacteria 1VUVY@1239,2F0XZ@1,33TZM@2,3F76N@33958,4HVU9@91061 NA|NA|NA S Phage tail tube protein LEHHPAIP_02151 557436.Lreu_1047 4.6e-227 793.5 Lactobacillaceae Bacteria 1TR5X@1239,3F57W@33958,4HBD9@91061,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain LEHHPAIP_02152 557436.Lreu_1046 1.5e-135 488.8 Lactobacillaceae Bacteria 1TPPI@1239,3FB7D@33958,4HAKP@91061,COG1484@1,COG1484@2 NA|NA|NA L Bacterial dnaA protein LEHHPAIP_02153 1074451.CRL705_1887 2.5e-105 388.3 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair LEHHPAIP_02154 575594.ACOH01000002_gene1122 6.3e-272 943.0 Lactobacillaceae ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein LEHHPAIP_02155 575594.ACOH01000002_gene1121 2.9e-144 518.1 Lactobacillaceae oppB ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP1S@1239,3F42T@33958,4HA2S@91061,COG0601@1,COG0601@2 NA|NA|NA P ABC-type dipeptide oligopeptide nickel transport systems, permease components LEHHPAIP_02156 575594.ACOH01000002_gene1120 3.7e-131 474.6 Lactobacillaceae oppC ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,3F3W3@33958,4H9PZ@91061,COG1173@1,COG1173@2 NA|NA|NA EP ABC-type dipeptide oligopeptide nickel transport systems, permease components LEHHPAIP_02157 575594.ACOH01000002_gene1119 1.2e-165 589.3 Lactobacillaceae oppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,3F41T@33958,4HA4E@91061,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily LEHHPAIP_02158 575594.ACOH01000002_gene1118 1.9e-137 495.4 Lactobacillaceae ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,3F4GM@33958,4H9YB@91061,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily LEHHPAIP_02159 349123.Lreu23DRAFT_3034 6.2e-160 570.5 Lactobacillaceae Bacteria 1TQQ0@1239,3F4D3@33958,4HDKW@91061,COG1228@1,COG1228@2 NA|NA|NA Q Imidazolonepropionase and related amidohydrolases LEHHPAIP_02160 575594.ACOH01000002_gene1117 8.3e-223 780.0 Lactobacillaceae dap2 3.4.19.1 ko:K01303 ko00000,ko01000,ko01002 Bacteria 1TR2N@1239,3F59I@33958,4H9RR@91061,COG1506@1,COG1506@2 NA|NA|NA E Prolyl oligopeptidase family LEHHPAIP_02161 575594.ACOH01000002_gene1116 6.9e-191 673.3 Lactobacillaceae Bacteria 1TQQ0@1239,3F4D3@33958,4HDKW@91061,COG1228@1,COG1228@2 NA|NA|NA Q Imidazolonepropionase and related amidohydrolases LEHHPAIP_02162 349123.Lreu23DRAFT_3037 4.7e-220 770.4 Lactobacillaceae dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2D@1239,3F541@33958,4HB9G@91061,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain LEHHPAIP_02163 575594.ACOH01000006_gene337 2.2e-81 308.9 Lactobacillaceae Bacteria 1TQ93@1239,3F4RB@33958,4HC0Q@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM Transposase, IS204 IS1001 IS1096 IS1165 LEHHPAIP_02164 575594.ACOH01000006_gene337 3e-45 188.3 Lactobacillaceae Bacteria 1TQ93@1239,3F4RB@33958,4HC0Q@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM Transposase, IS204 IS1001 IS1096 IS1165 LEHHPAIP_02165 557436.Lreu_1594 9.5e-39 165.6 Lactobacillaceae Bacteria 1V64Y@1239,3F812@33958,4HNUM@91061,COG4892@1,COG4892@2 NA|NA|NA S Cytochrome B5 LEHHPAIP_02166 349123.Lreu23DRAFT_4473 7.5e-275 952.6 Lactobacillaceae arcD Bacteria 1TQJ0@1239,3F4C3@33958,4H9P7@91061,COG1288@1,COG1288@2 NA|NA|NA S C4-dicarboxylate anaerobic carrier LEHHPAIP_02167 557436.Lreu_1544 1.7e-259 901.4 Lactobacillaceae ytjP 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPEG@1239,3F3TS@33958,4HBNX@91061,COG0624@1,COG0624@2 NA|NA|NA E Dipeptidase LEHHPAIP_02168 557436.Lreu_1543 8.2e-216 756.1 Lactobacillaceae uhpT Bacteria 1TQZ7@1239,3F54C@33958,4HERG@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_02169 557436.Lreu_1542 4.9e-284 983.0 Lactobacillaceae gtfA GO:0003674,GO:0003824,GO:0004645,GO:0009018,GO:0016740,GO:0016757,GO:0016758 2.4.1.7 ko:K00690 ko00500,map00500 R00803 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1TR93@1239,3FB7X@33958,4HDDA@91061,COG0366@1,COG0366@2 NA|NA|NA G Sucrose glucosyltransferase LEHHPAIP_02170 557436.Lreu_1541 7e-131 473.4 Lactobacillaceae ponA Bacteria 1VBZ3@1239,3F672@33958,4HN99@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family LEHHPAIP_02171 557436.Lreu_1540 1.4e-231 808.5 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family LEHHPAIP_02172 557436.Lreu_1539 1.4e-72 278.9 Lactobacillaceae Bacteria 1VKTU@1239,2DS5S@1,33ENY@2,3F6MW@33958,4HSXX@91061 NA|NA|NA LEHHPAIP_02173 349123.Lreu23DRAFT_3266 0.0 1483.0 Lactobacillaceae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase LEHHPAIP_02174 557436.Lreu_0909 1.5e-186 658.7 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3FC5D@33958,4HEN1@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain LEHHPAIP_02175 349123.Lreu23DRAFT_3262 6.4e-170 603.2 Lactobacillaceae scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,3F3K8@33958,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family LEHHPAIP_02176 557436.Lreu_0907 1.8e-173 615.1 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family LEHHPAIP_02177 557436.Lreu_0903 1.3e-45 188.7 Lactobacillaceae lytS 2.7.13.3 ko:K02478,ko:K07704 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1VTXF@1239,3F42A@33958,4H9Z1@91061,COG3275@1,COG3275@2 NA|NA|NA T LytS YhcK-type transmembrane receptor domain protein LEHHPAIP_02178 349123.Lreu23DRAFT_3256 4.4e-147 527.3 Lactobacillaceae f42a Bacteria 1TRN5@1239,3F4ES@33958,4HA6G@91061,COG0330@1,COG0330@2 NA|NA|NA O Band 7 protein LEHHPAIP_02179 557436.Lreu_0901 3.7e-257 893.6 Lactobacillaceae rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 ko00000,ko01000,ko03009 Bacteria 1TPGQ@1239,3F492@33958,4HCHQ@91061,COG0144@1,COG0144@2,COG3270@1,COG3270@2 NA|NA|NA J NOL1 NOP2 sun family protein LEHHPAIP_02180 349123.Lreu23DRAFT_3254 1e-153 549.3 Lactobacillaceae yitU 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TREF@1239,3F47B@33958,4H9Y9@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase LEHHPAIP_02181 349123.Lreu23DRAFT_3253 9.2e-39 165.6 Lactobacillaceae Bacteria 1V64Y@1239,3F812@33958,4HNUM@91061,COG4892@1,COG4892@2 NA|NA|NA S Cytochrome B5 LEHHPAIP_02182 557436.Lreu_0898 1.3e-114 419.1 Lactobacillaceae nreC ko:K02282,ko:K07696 ko02020,map02020 M00483 ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 Bacteria 1TSBV@1239,3FC2M@33958,4HC74@91061,COG2197@1,COG2197@2 NA|NA|NA K PFAM regulatory protein LuxR LEHHPAIP_02183 349123.Lreu23DRAFT_3250 5.2e-159 567.0 Lactobacillaceae hipB GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K15773 ko00000,ko02048,ko03000 Bacteria 1VDMN@1239,3F5A3@33958,4HDVP@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix LEHHPAIP_02184 557436.Lreu_0896 8.1e-57 226.1 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1VCAX@1239,3FCDE@33958,4HNBK@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein LEHHPAIP_02185 557436.Lreu_0895 1.2e-271 941.8 Lactobacillaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 1TQ21@1239,3F44I@33958,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB LEHHPAIP_02186 557436.Lreu_0894 3.6e-79 300.8 Lactobacillaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,3F6WP@33958,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family LEHHPAIP_02187 349123.Lreu23DRAFT_3246 5.2e-234 816.6 Lactobacillaceae sufS 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TQ1W@1239,3F3UP@33958,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine LEHHPAIP_02188 557436.Lreu_0892 1.7e-240 838.2 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,3F4BR@33958,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD LEHHPAIP_02189 349123.Lreu23DRAFT_3244 1.9e-144 518.5 Lactobacillaceae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,3F3XT@33958,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC LEHHPAIP_02190 349123.Lreu23DRAFT_3243 2.8e-31 140.6 Lactobacillaceae feoA ko:K04758 ko00000,ko02000 Bacteria 1U69I@1239,3F7DB@33958,4IG0P@91061,COG1918@1,COG1918@2 NA|NA|NA P FeoA domain LEHHPAIP_02191 557436.Lreu_0890 0.0 1255.0 Lactobacillaceae feoB ko:K04759 ko00000,ko02000 9.A.8.1 iSB619.SA_RS13395 Bacteria 1TP7E@1239,3F553@33958,4HBCS@91061,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system LEHHPAIP_02192 557436.Lreu_0888 6.3e-268 929.5 Lactobacillaceae menE 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPSX@1239,3F453@33958,4HACS@91061,COG0318@1,COG0318@2 NA|NA|NA H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily LEHHPAIP_02193 557436.Lreu_0887 2.9e-156 557.8 Lactobacillaceae menB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071890,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNU@1239,3F5HN@33958,4HAD0@91061,COG0447@1,COG0447@2 NA|NA|NA H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) LEHHPAIP_02194 557436.Lreu_0886 6.7e-60 236.5 Lactobacillaceae ydiI Bacteria 1V7G2@1239,3F7FT@33958,4HIIA@91061,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily LEHHPAIP_02195 557436.Lreu_0885 7.1e-109 399.8 Bacteria yvrI ko:K03091,ko:K03093 ko00000,ko03021 Bacteria COG1191@1,COG1191@2 NA|NA|NA K sigma factor activity LEHHPAIP_02196 349123.Lreu23DRAFT_3237 1.3e-205 722.2 Lactobacillaceae Bacteria 1TP6X@1239,3F54E@33958,4IQRU@91061,COG2271@1,COG2271@2 NA|NA|NA G Transporter, major facilitator family protein LEHHPAIP_02197 557436.Lreu_0883 0.0 1857.4 Lactobacillaceae Bacteria 1TPVY@1239,3F4AK@33958,4HD9X@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO LEHHPAIP_02198 349123.Lreu23DRAFT_3235 3.3e-103 381.3 Lactobacillaceae GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K10716 ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 1UI86@1239,3FBVA@33958,4ITAR@91061,COG0664@1,COG0664@2 NA|NA|NA T Ion transport 2 domain protein LEHHPAIP_02199 557436.Lreu_0877 9.9e-177 625.9 Lactobacillaceae rihA GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0047405,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 iEC55989_1330.EC55989_0645,iECSE_1348.ECSE_0721,iEcE24377_1341.EcE24377A_0679,iSbBS512_1146.SbBS512_E0598 Bacteria 1TSSS@1239,3FB76@33958,4HEK7@91061,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase LEHHPAIP_02201 543734.LCABL_13380 5.9e-23 113.6 Lactobacillaceae Bacteria 1VHHD@1239,2EBTF@1,333J2@2,3FBPF@33958,4HQFJ@91061 NA|NA|NA S Phage tail assembly chaperone protein, TAC LEHHPAIP_02202 1154757.Q5C_03150 7.7e-23 113.2 Leuconostocaceae Bacteria 1U22W@1239,2EBTF@1,307RB@2,4AYJH@81850,4IGDZ@91061 NA|NA|NA S Phage tail assembly chaperone protein, TAC LEHHPAIP_02203 557436.Lreu_1546 5.2e-181 640.2 Lactobacillaceae yfeX ko:K07223 ko00000 Bacteria 1UY9Y@1239,3F45Z@33958,4HACQ@91061,COG2837@1,COG2837@2 NA|NA|NA P Peroxidase LEHHPAIP_02204 349123.Lreu23DRAFT_4328 3.7e-205 720.7 Lactobacillaceae amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1TQYG@1239,3F3X1@33958,4HBGK@91061,COG0004@1,COG0004@2 NA|NA|NA P ammonium transporter LEHHPAIP_02205 557436.Lreu_1411 6.8e-248 862.8 Lactobacillaceae gor 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1VTHV@1239,3FC6U@33958,4HV84@91061,COG1249@1,COG1249@2 NA|NA|NA C pyridine nucleotide-disulfide oxidoreductase LEHHPAIP_02206 349123.Lreu23DRAFT_4326 8.6e-84 316.2 Lactobacillaceae yvbK 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3IC@1239,3F7GI@33958,4HH45@91061,COG0454@1,COG0456@2 NA|NA|NA K GNAT family LEHHPAIP_02207 349123.Lreu23DRAFT_4325 1.7e-91 342.0 Lactobacillaceae Bacteria 1W6IZ@1239,28WK8@1,2ZIK8@2,3F68J@33958,4I01D@91061 NA|NA|NA LEHHPAIP_02208 557436.Lreu_1408 4.1e-121 440.7 Lactobacillaceae pnb Bacteria 1V6AG@1239,3F6YM@33958,4HN5N@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase LEHHPAIP_02209 557436.Lreu_1407 2.4e-75 288.1 Lactobacillaceae ogt 2.1.1.63 ko:K00567 ko00000,ko01000,ko03400 Bacteria 1VA03@1239,3F6RF@33958,4HETA@91061,COG0350@1,COG0350@2 NA|NA|NA L Methyltransferase LEHHPAIP_02210 349123.Lreu23DRAFT_4320 1.2e-155 555.8 Lactobacillaceae 3.2.1.96,3.5.1.28 ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 R04112 RC00064,RC00141 ko00000,ko00001,ko01000 GH73 Bacteria 1V3MY@1239,3F4BU@33958,4HBWG@91061,COG5632@1,COG5632@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase LEHHPAIP_02211 349123.Lreu23DRAFT_4319 6.8e-67 260.0 Lactobacillaceae Bacteria 1VHBQ@1239,2E0UI@1,32WBZ@2,3F7MD@33958,4IR8K@91061 NA|NA|NA S Protein of unknown function (DUF3021) LEHHPAIP_02212 557436.Lreu_1401 6e-76 290.0 Lactobacillaceae Bacteria 1VD10@1239,3F6QC@33958,4HMF3@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain LEHHPAIP_02213 557436.Lreu_1400 1.1e-92 345.9 Bacilli Bacteria 1V239@1239,4ITPJ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family LEHHPAIP_02216 525309.HMPREF0494_0797 2.4e-178 631.7 Lactobacillaceae ycsG Bacteria 1TP0Q@1239,3F582@33958,4HAYE@91061,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein LEHHPAIP_02217 1203076.CAKF01000010_gene142 5.8e-103 380.6 Lactobacillaceae ycsF ko:K07160 ko00000 Bacteria 1TR8X@1239,3F3Q3@33958,4H9PF@91061,COG1540@1,COG1540@2 NA|NA|NA S LamB/YcsF family LEHHPAIP_02218 525309.HMPREF0494_0795 3.5e-207 727.6 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit LEHHPAIP_02219 525309.HMPREF0494_0794 3.8e-38 164.5 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VH23@1239,3F7QZ@33958,4HQHP@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA LEHHPAIP_02220 525309.HMPREF0494_0793 3.1e-107 395.2 Lactobacillaceae kipA 6.3.4.6 ko:K01941,ko:K06350 ko00220,ko00791,ko01100,map00220,map00791,map01100 R00774 RC00378 ko00000,ko00001,ko01000 Bacteria 1TR6U@1239,3F545@33958,4HACC@91061,COG1984@1,COG1984@2 NA|NA|NA E Allophanate hydrolase subunit 2 LEHHPAIP_02221 525309.HMPREF0494_0792 7.7e-84 317.0 Lactobacillaceae ybgJ 3.5.1.54 ko:K01457,ko:K06351,ko:K07160 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 R00005 RC02756 ko00000,ko00001,ko01000 Bacteria 1TTBZ@1239,3F64P@33958,4HHJJ@91061,COG2049@1,COG2049@2 NA|NA|NA E Allophanate hydrolase subunit 1 LEHHPAIP_02222 1069534.LRC_03190 2.2e-41 175.6 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3FBIW@33958,4IQTG@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily LEHHPAIP_02224 334390.LAF_0232 6.2e-171 606.7 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily LEHHPAIP_02225 334390.LAF_0233 3.3e-110 404.4 Lactobacillaceae tesE ko:K02509 ko00350,ko01120,map00350,map01120 R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 Bacteria 1TQVG@1239,3F515@33958,4HBMC@91061,COG3971@1,COG3971@2 NA|NA|NA Q hydratase LEHHPAIP_02226 525309.HMPREF0494_0791 5.3e-64 251.1 Lactobacillaceae birA 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor LEHHPAIP_02227 525309.HMPREF0494_0790 0.0 1881.7 Lactobacillaceae pyc GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHP9@1239,3F4U7@33958,4IS56@91061,COG1038@1,COG1038@2 NA|NA|NA C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second LEHHPAIP_02228 1423814.HMPREF0549_1566 1.6e-296 1024.6 Lactobacillaceae mco Bacteria 1TQSU@1239,3F3XB@33958,4HDD6@91061,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase LEHHPAIP_02229 349123.Lreu23DRAFT_3438 1.7e-127 462.2 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region LEHHPAIP_02230 797515.HMPREF9103_01651 8.7e-113 413.7 Lactobacillaceae fic Bacteria 1TQMC@1239,3F45Y@33958,4HBA4@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family LEHHPAIP_02231 525365.HMPREF0548_0512 2e-129 469.2 Lactobacillaceae ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1U59Y@1239,3F5BK@33958,4IF1G@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family LEHHPAIP_02232 1203076.CAKF01000019_gene1320 4e-19 100.1 Lactobacillaceae Bacteria 1U70T@1239,29PP2@1,30ARK@2,3F8TQ@33958,4IGV4@91061 NA|NA|NA LEHHPAIP_02235 557436.Lreu_1610 2.2e-153 550.1 Lactobacillaceae Bacteria 1U7AA@1239,29Q0G@1,30AYY@2,3F970@33958,4IH58@91061 NA|NA|NA LEHHPAIP_02237 575594.ACOH01000016_gene1578 1.6e-76 292.4 Lactobacillaceae Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain LEHHPAIP_02238 575594.ACOH01000016_gene1578 3.8e-10 72.0 Lactobacillaceae Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain LEHHPAIP_02239 575594.ACOH01000016_gene1577 2.8e-13 82.0 Bacteria dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease LEHHPAIP_02242 557436.Lreu_0275 1.4e-18 98.2 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family LEHHPAIP_02245 557436.Lreu_0576 4.9e-60 236.9 Lactobacillaceae XK27_01125 ko:K07484 ko00000 Bacteria 1VAJD@1239,3F7E1@33958,4HKCG@91061,COG3436@1,COG3436@2 NA|NA|NA L PFAM IS66 Orf2 family protein LEHHPAIP_02246 349123.Lreu23DRAFT_4610 8e-182 642.9 Lactobacillaceae iunH2 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSAR@1239,3F4A3@33958,4HDCS@91061,COG1957@1,COG1957@2 NA|NA|NA F nucleoside hydrolase LEHHPAIP_02247 349123.Lreu23DRAFT_4609 4.9e-182 643.7 Lactobacillaceae yumC GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.18.1.2,1.19.1.1,1.8.1.9 ko:K00384,ko:K21567 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 iYO844.BSU32110 Bacteria 1TRPN@1239,3F3NQ@33958,4H9V7@91061,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase LEHHPAIP_02248 349123.Lreu23DRAFT_4596 4.6e-35 153.3 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TWKK@1239,3F6CT@33958,4HCXI@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase LEHHPAIP_02249 349123.Lreu23DRAFT_4596 1.2e-95 355.9 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TWKK@1239,3F6CT@33958,4HCXI@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase LEHHPAIP_02250 349123.Lreu23DRAFT_4595 1.3e-114 419.1 Lactobacillaceae gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V7U6@1239,3F658@33958,4HJ9I@91061,COG0546@1,COG0546@2 NA|NA|NA S HAD hydrolase, family IA, variant LEHHPAIP_02251 557436.Lreu_1651 9.7e-178 629.4 Lactobacillaceae yagE Bacteria 1VTJD@1239,3FCAN@33958,4HTQM@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_02252 349123.Lreu23DRAFT_4594 4.6e-52 210.3 Lactobacillaceae yagE Bacteria 1VTJD@1239,3FCAN@33958,4HTQM@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid LEHHPAIP_02253 349123.Lreu23DRAFT_4593 3.8e-84 317.4 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,3F5WI@33958,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family LEHHPAIP_02254 557436.Lreu_1649 0.0 1681.4 Lactobacillaceae pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase LEHHPAIP_02255 557436.Lreu_1648 2.3e-178 631.3 Lactobacillaceae pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1UEDT@1239,3F47H@33958,4HF61@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates LEHHPAIP_02256 349123.Lreu23DRAFT_4590 0.0 1595.5 Lactobacillaceae pepX 3.4.14.11 ko:K01281 ko00000,ko01000,ko01002 Bacteria 1TT78@1239,3F44E@33958,4HBA0@91061,COG2936@1,COG2936@2 NA|NA|NA E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline LEHHPAIP_02257 557436.Lreu_1080 8.9e-130 469.5 Lactobacillaceae menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQEA@1239,3FC67@33958,4HJYK@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) LEHHPAIP_02258 349123.Lreu23DRAFT_5172 8.2e-224 782.7 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_02259 349123.Lreu23DRAFT_5173 1.7e-167 595.1 Lactobacillaceae Bacteria 1UZK9@1239,3F5JR@33958,4HG1F@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain LEHHPAIP_02260 557436.Lreu_1077 7e-43 179.5 Lactobacillaceae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3F7KX@33958,4HKK1@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site LEHHPAIP_02261 334390.LAF_0134 4.2e-49 201.1 Lactobacillaceae ko:K07491 ko00000 Bacteria 1V4ET@1239,3F7IF@33958,4HH13@91061,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like LEHHPAIP_02262 334390.LAF_0133 2.5e-185 654.8 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family LEHHPAIP_02265 349123.Lreu23DRAFT_5176 1.1e-121 442.6 Lactobacillaceae sdaAB 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1U8TZ@1239,3F4UB@33958,4HBD6@91061,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain LEHHPAIP_02266 349123.Lreu23DRAFT_5177 3.7e-141 507.7 Lactobacillaceae sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,3F3X8@33958,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase, iron-sulfur-dependent, alpha subunit LEHHPAIP_02267 349123.Lreu23DRAFT_5178 3.6e-105 387.5 Lactobacillaceae ahpC 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1TQU7@1239,3F50G@33958,4HA2M@91061,COG0450@1,COG0450@2 NA|NA|NA O Peroxiredoxin LEHHPAIP_02268 557436.Lreu_1071 0.0 1098.6 Lactobacillaceae trxB2 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F5GD@33958,4HD19@91061,COG0492@1,COG0492@2,COG3634@1,COG3634@2 NA|NA|NA C Thioredoxin domain LEHHPAIP_02269 557436.Lreu_1068 4.9e-273 946.4 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase LEHHPAIP_02270 349123.Lreu23DRAFT_3733 2.5e-311 1073.5 Lactobacillaceae yjbQ ko:K03455,ko:K03499 ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 Bacteria 1TS32@1239,3F4AZ@33958,4H9Q5@91061,COG0475@1,COG0475@2,COG0569@1,COG0569@2 NA|NA|NA P TrkA C-terminal domain protein LEHHPAIP_02271 349123.Lreu23DRAFT_3734 2.7e-25 120.6 Lactobacillaceae dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1VKD5@1239,3F83T@33958,4HRBS@91061,COG1942@1,COG1942@2 NA|NA|NA G Belongs to the 4-oxalocrotonate tautomerase family LEHHPAIP_02272 349123.Lreu23DRAFT_3735 6.6e-292 1009.2 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate LEHHPAIP_02273 349123.Lreu23DRAFT_3736 4.3e-86 323.9 Lactobacillaceae Bacteria 1U849@1239,29QHP@1,30BH5@2,3FAID@33958,4II1Q@91061 NA|NA|NA LEHHPAIP_02274 349123.Lreu23DRAFT_3207 1.1e-264 918.7 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3F59Y@33958,4HBHG@91061,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase catalytic region LEHHPAIP_02275 349123.Lreu23DRAFT_3737 4.7e-35 153.3 Lactobacillaceae Bacteria 1U733@1239,2AG27@1,3166I@2,3F8WV@33958,4IGXM@91061 NA|NA|NA LEHHPAIP_02276 557436.Lreu_1062 3.5e-61 240.7 Lactobacillaceae Bacteria 1VB21@1239,3F898@33958,4HMT8@91061,COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation LEHHPAIP_02277 349123.Lreu23DRAFT_3740 2.6e-40 171.0 Lactobacillaceae Bacteria 1U6N9@1239,29PIU@1,30AGZ@2,3F86N@33958,4IGF9@91061 NA|NA|NA K Transcriptional regulator, HxlR family LEHHPAIP_02278 557436.Lreu_1057 4.9e-166 590.5 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein LEHHPAIP_02279 349123.Lreu23DRAFT_3742 9e-140 503.1 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein LEHHPAIP_02280 349123.Lreu23DRAFT_3743 2.8e-118 431.4 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family LEHHPAIP_02281 1169144.KB910944_gene2371 2.2e-50 205.7 Bacillus pglC ko:K13012 ko00000,ko01005 Bacteria 1TQX9@1239,1ZQHD@1386,4HAF1@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase LEHHPAIP_02282 334390.LAF_0089 1.5e-83 316.2 Lactobacillaceae lsgF Bacteria 1V1CB@1239,3F78V@33958,4I2AI@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 LEHHPAIP_02283 158787.BSCA_0263 2.1e-33 149.8 Bifidobacteriales 2.4.1.166 ko:K00745 ko00000,ko01000 GT2 Bacteria 2I2GT@201174,4CZ0W@85004,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 LEHHPAIP_02285 1158607.UAU_04641 6.1e-67 261.9 Enterococcaceae cps2I Bacteria 1TR1W@1239,4B4J4@81852,4HCW6@91061,COG2244@1,COG2244@2 NA|NA|NA S Psort location CytoplasmicMembrane, score LEHHPAIP_02286 1158602.I590_02234 4.8e-38 164.9 Enterococcaceae Bacteria 1V3YG@1239,4B3FG@81852,4HG22@91061,COG3774@1,COG3774@2 NA|NA|NA M Glycosyltransferase sugar-binding region containing DXD motif LEHHPAIP_02287 1280671.AUJH01000002_gene1591 5.3e-45 188.3 Butyrivibrio cpsJ Bacteria 1VATJ@1239,24H9J@186801,4C1T2@830,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase like family 2 LEHHPAIP_02288 1158602.I590_02234 6.2e-38 164.5 Enterococcaceae Bacteria 1V3YG@1239,4B3FG@81852,4HG22@91061,COG3774@1,COG3774@2 NA|NA|NA M Glycosyltransferase sugar-binding region containing DXD motif LEHHPAIP_02289 762968.HMPREF9441_02688 2.4e-60 239.6 Bacteroidetes Bacteria 4NJ6M@976,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase, group 2 family protein LEHHPAIP_02290 469617.FUAG_01654 2.3e-07 63.5 Fusobacteria Bacteria 3794P@32066,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 LEHHPAIP_02291 931276.Cspa_c53530 1.3e-47 196.4 Clostridiaceae Z012_10770 Bacteria 1V8R9@1239,24IIJ@186801,36IZT@31979,COG3955@1,COG3955@2 NA|NA|NA M Domain of unknown function (DUF1919) LEHHPAIP_02292 349123.Lreu23DRAFT_4269 5.6e-197 693.3 Lactobacillaceae rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,3F3R6@33958,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily LEHHPAIP_02293 349123.Lreu23DRAFT_3321 2e-36 157.9 Lactobacillaceae Bacteria 1UIMF@1239,2AQ9M@1,31FFI@2,3FBVB@33958,4ISND@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) LEHHPAIP_02294 349123.Lreu23DRAFT_3551 1.1e-33 148.7 Lactobacillaceae oxc GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0008949,GO:0009056,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019752,GO:0019842,GO:0030554,GO:0030976,GO:0032553,GO:0032555,GO:0032559,GO:0033609,GO:0033611,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0097159,GO:0097367,GO:0104004,GO:1901265,GO:1901363,GO:1901575,GO:1901681 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 R01908 RC00620 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2523,iNJ661.Rv0118c Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family LEHHPAIP_02295 349123.Lreu23DRAFT_3551 2e-32 144.4 Lactobacillaceae oxc GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0008949,GO:0009056,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019752,GO:0019842,GO:0030554,GO:0030976,GO:0032553,GO:0032555,GO:0032559,GO:0033609,GO:0033611,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0097159,GO:0097367,GO:0104004,GO:1901265,GO:1901363,GO:1901575,GO:1901681 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 R01908 RC00620 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2523,iNJ661.Rv0118c Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family LEHHPAIP_02296 557436.Lreu_0494 9.1e-126 456.4 Lactobacillaceae oxc GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0008949,GO:0009056,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019752,GO:0019842,GO:0030554,GO:0030976,GO:0032553,GO:0032555,GO:0032559,GO:0033609,GO:0033611,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0097159,GO:0097367,GO:0104004,GO:1901265,GO:1901363,GO:1901575,GO:1901681 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 R01908 RC00620 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2523,iNJ661.Rv0118c Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family LEHHPAIP_02297 557436.Lreu_0494 3.7e-67 260.8 Lactobacillaceae oxc GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0008949,GO:0009056,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019752,GO:0019842,GO:0030554,GO:0030976,GO:0032553,GO:0032555,GO:0032559,GO:0033609,GO:0033611,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0097159,GO:0097367,GO:0104004,GO:1901265,GO:1901363,GO:1901575,GO:1901681 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 R01908 RC00620 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2523,iNJ661.Rv0118c Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family LEHHPAIP_02298 557436.Lreu_0493 5.5e-138 496.9 Lactobacillaceae ko:K09861 ko00000 Bacteria 1TR33@1239,3FBM0@33958,4IR25@91061,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family LEHHPAIP_02299 349123.Lreu23DRAFT_3549 2.1e-137 495.0 Lactobacillaceae Bacteria 1VSZX@1239,3F4ZU@33958,4HTJ1@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane LEHHPAIP_02300 349123.Lreu23DRAFT_3548 6.8e-74 283.1 Lactobacillaceae 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1V7XP@1239,3F679@33958,4HXCD@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase LEHHPAIP_02301 349123.Lreu23DRAFT_4451 3.9e-159 567.4 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family LEHHPAIP_02302 557436.Lreu_1527 9.4e-253 879.0 Lactobacillaceae yjjP Bacteria 1TNZH@1239,3F4FR@33958,4HU4D@91061,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Putative threonine/serine exporter LEHHPAIP_02303 557436.Lreu_1526 4.7e-117 427.2 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V4M9@1239,3FB9B@33958,4HMW1@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase LEHHPAIP_02304 349123.Lreu23DRAFT_4448 6.5e-271 939.5 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_02305 349123.Lreu23DRAFT_4447 9.4e-186 656.0 Lactobacillaceae Bacteria 1V1HV@1239,3F5YJ@33958,4HE9T@91061,COG0657@1,COG0657@2 NA|NA|NA I Alpha beta LEHHPAIP_02306 557436.Lreu_1523 9.8e-103 379.4 Lactobacillaceae thiJ 2.7.11.1,3.5.1.124 ko:K03152,ko:K05520,ko:K12132 ko00000,ko01000,ko01001,ko01002 Bacteria 1V3UV@1239,3F3T7@33958,4IQYM@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family LEHHPAIP_02307 557436.Lreu_1522 0.0 1671.4 Lactobacillaceae mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 iYO844.BG12900 Bacteria 1TQI2@1239,3F3PY@33958,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2 NA|NA|NA S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms LEHHPAIP_02309 557436.Lreu_1521 4.3e-166 590.5 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F46Z@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil LEHHPAIP_02310 557436.Lreu_1520 2.7e-121 441.4 Lactobacillaceae Bacteria 1VF04@1239,2DQII@1,33737@2,3FBPG@33958,4IRPI@91061 NA|NA|NA S Domain of unknown function (DUF4811) LEHHPAIP_02311 557436.Lreu_1519 7.2e-270 936.0 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LEHHPAIP_02312 557436.Lreu_1518 3.4e-74 284.3 Lactobacillaceae merR ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1VDPP@1239,3F6MS@33958,4HPJY@91061,COG0789@1,COG0789@2 NA|NA|NA K MerR HTH family regulatory protein LEHHPAIP_02313 557436.Lreu_1517 2.9e-57 227.6 Lactobacillaceae Bacteria 1U6HY@1239,29PFD@1,30ADI@2,3F7YB@33958,4IGA9@91061 NA|NA|NA LEHHPAIP_02314 557436.Lreu_1516 0.0 1171.0 Lactobacillaceae rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3TT@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay LEHHPAIP_02315 557436.Lreu_1515 8.3e-221 772.7 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VNA9@1239,3F5T9@33958,4HRMP@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity LEHHPAIP_02316 349123.Lreu23DRAFT_4437 1e-108 399.4 Lactobacillaceae glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K02029,ko:K10002,ko:K10040 ko02010,ko02020,map02010,map02020 M00228,M00230,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 Bacteria 1UJM4@1239,3F3WJ@33958,4HBAS@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease LEHHPAIP_02317 557436.Lreu_1513 2.4e-110 404.8 Lactobacillaceae gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 1TQ5K@1239,3F3XW@33958,4HFBH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease LEHHPAIP_02318 557436.Lreu_1512 7.5e-152 543.1 Lactobacillaceae glnH ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3FC55@33958,4HBM1@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter LEHHPAIP_02319 557436.Lreu_1511 1.4e-133 482.3 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10041 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein LEHHPAIP_02320 557436.Lreu_1510 5.5e-83 313.5 Lactobacillaceae usp1 Bacteria 1V8UY@1239,3F6N5@33958,4HK2J@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family LEHHPAIP_02321 349123.Lreu23DRAFT_4432 8.4e-109 399.8 Lactobacillaceae Bacteria 1V6KW@1239,3FBCU@33958,4HEC6@91061,COG1814@1,COG1814@2 NA|NA|NA S VIT family LEHHPAIP_02322 349123.Lreu23DRAFT_4431 2.5e-116 424.9 Lactobacillaceae Bacteria 1V26W@1239,3F3TU@33958,4HGMW@91061,COG1814@1,COG1814@2 NA|NA|NA S membrane LEHHPAIP_02323 557436.Lreu_1507 5.5e-164 583.6 Lactobacillaceae czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,3F4KJ@33958,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter LEHHPAIP_02324 557436.Lreu_1506 1.6e-123 448.7 Lactobacillaceae sirR ko:K03709 ko00000,ko03000 Bacteria 1V3IS@1239,3F405@33958,4HH06@91061,COG1321@1,COG1321@2 NA|NA|NA K iron dependent repressor LEHHPAIP_02325 349123.Lreu23DRAFT_4428 1e-30 138.7 Lactobacillaceae cspC ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7FW@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein LEHHPAIP_02326 349123.Lreu23DRAFT_4427 2e-127 461.8 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter LEHHPAIP_02327 349123.Lreu23DRAFT_4426 1e-81 309.3 Lactobacillaceae Bacteria 1V6P0@1239,3F63I@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE LEHHPAIP_02328 557436.Lreu_1502 4.4e-118 430.6 Lactobacillaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VY85@1239,3F4DD@33958,4HXM4@91061,COG0671@1,COG0671@2 NA|NA|NA I phosphatase LEHHPAIP_02329 1423807.BACO01000023_gene723 6.6e-09 67.4 Lactobacillaceae 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1VQDG@1239,3F8SE@33958,4IFZI@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain LEHHPAIP_02330 557436.Lreu_1500 1.5e-275 954.9 Lactobacillaceae lysP ko:K03293,ko:K11733,ko:K16235 ko00000,ko02000 2.A.3.1,2.A.3.1.10,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid LEHHPAIP_02331 557436.Lreu_1498 1.1e-113 416.0 Lactobacillaceae dak 2.7.1.74,2.7.1.76 ko:K00893,ko:K10353 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase LEHHPAIP_02337 908339.HMPREF9265_0137 9.8e-186 656.4 Lactobacillaceae 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UYTM@1239,3FBD6@33958,4IPJ9@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain LEHHPAIP_02338 525309.HMPREF0494_1275 1.8e-59 236.1 Lactobacillaceae Bacteria 1U6XG@1239,2DKSQ@1,30ANY@2,3F8NZ@33958,4IGRS@91061 NA|NA|NA S Double zinc ribbon LEHHPAIP_02339 525309.HMPREF0494_1271 2.8e-49 202.2 Lactobacillaceae agrA ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1UV9A@1239,3F5N7@33958,4I490@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain LEHHPAIP_02340 575594.ACOH01000017_gene1553 3.6e-47 194.9 Lactobacillaceae Bacteria 1U67J@1239,2DKP0@1,30A53@2,3F798@33958,4IFY4@91061 NA|NA|NA LEHHPAIP_02341 575594.ACOH01000017_gene1552 2.2e-09 70.1 Lactobacillaceae Bacteria 1U5R7@1239,2CC5Z@1,309UP@2,3F6CR@33958,4IFF8@91061 NA|NA|NA S zinc-ribbon domain LEHHPAIP_02345 575594.ACOH01000018_gene1499 1.3e-28 135.6 Lactobacillaceae ebh ko:K08086 ko00000 Bacteria 1W39C@1239,3F754@33958,4I0DV@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation # 2034 queries scanned # Total time (seconds): 4.83064198494 # Rate: 421.06 q/s