LOCUS       c00022_JAIBNY0..       15661 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIBNY010000009.1 Lactiplantibacillus plantarum strain GUANKE
            NODE_9_length_92836_cov_50.264710, whole genome shotgun sequence.
ACCESSION   JAIBNY010000009
VERSION     JAIBNY010000009
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 00:44:45
            Original ID  :: JAIBNY010000009.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15661
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15661
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4779:5661](-)"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4780..5661)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..15661
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15661
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             2..148
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MKLVTVGTNFKNQRRKQMGRETKIRFLVPFAYTEASYVTASFIMI
                     KTC"
     CDS             complement(304..633)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MDVDAQKLFTLVDAAYNQPITNQPSDSYRQALLAAAIDLNNNVSP
                     QQVTIQLYQAYYRNYMVPMTLPRQHRDLYQYVHTQLQRLTRKEQRHMALGYGLIATHLT
                     FGPLN"
     CDS             complement(828..2162)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 334.7; E-value: 1.1e-101)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_3"
                     /transl_table=11
                     /translation="MTNKYDYDVLYIGAGHATFDGAAPLAKTGVRVGVIESGLIGGTCP
                     NRGCNAKITLDEPVKLTREAARLNDILSSAPTINWTANVAHKQEIIDPLPAGLTARLED
                     GGATIIHGHATFKDAHTVVVDDQQNITAEKIVIATGLKPHRLDIPGTKLAHDSSDFMNL
                     KRLPQSIVIIGAGYIGMEFATIANAAGAQVTVMLHGDQALRDFYQPFVAQVVDDLTERG
                     VTFIKNANVQAFTKQDDQFQVSYGDHQQLTTDWILDATGRIPNLDGLGLDRIGVKYDHH
                     GVYVNDHLQTNVPNIYAAGDVLANDLPKVTPAAYFESKYLMRLFSGQTSAPIDYPVIPS
                     VVFTSPRIAQAGMKIPAAEKAGLTVSDNDLADYWYYQVSKEPIAASKQVHDQDGHLVGV
                     TEISDQAEDAVNALLPAIEYQLDREQIDRLIGIFPTIGYAAWHRA"
     CDS             2298..3410
                     /locus_tag="ctg22_4"
                     /transl_table=11
                     /translation="MHALIAIDSFKNSITSIQANRIVAKRFAAHGITATQVAIADGGEG
                     TVAAWLANHVGGQAITASTVDLAQRPVTATYGYFATEKMAVIEVAAASGIQFVTTTLTP
                     LATNTYGTGLLIKDAIERGARQIILGLGGSGTVDGGAGILRALGYRFWAADGQELAMTG
                     ADLSRVTKIDDRHVLPQLAEVSFISAADVTNPLTGPNGAAKVFGPQKGLPVAQIQAHDA
                     ALAHYMTVAAGAVSAHEGDGAAGGIGFALRYFLHARVRSGFQLLAEMSNLKTKVAQADL
                     VISGEGQVDDQSFMGKVPIQLSQLAQAAGKPCYLLVGRQKGANETFAKQGVTAVLPIVD
                     QVMTLDQAMAQGPANLERMADRLARIISQS"
     CDS             complement(3477..4418)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="PF00561 (E-value: 3.9e-08, bitscore: 25.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTRAVAGISAPVAIFSAALFASEKLYDFAFKRVDYVPETSADK
                     QKYADAYYAYVDWLHRQPVQQWQLNANDEANHLVAQYVPAKTTSNRTVIVSHGYKGDGE
                     TMANYAYMFHQMGYNVLLPDDRGHGQSAGKYISFGWQDRRDYLGWIDKVVRINGRHTDI
                     ILFGVSMGGATVEMMSGEDLPSQVKAIIADCGYSSIEEELAYLLKRQFHLPKYPFVPIV
                     SFINRHRMGYYLSDVSSVEQLKHNHLPIFFIHGDKDVYVPSWMLKENYQAAKGPKQMWQ
                     VPNATHAESFWIDPAEYQRHVTAFLNHYVPDK"
     CDS             complement(4780..5661)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_6"
                     /sec_met_domain="phytoene_synt (E-value: 5.5e-57, bitscore:
                     185.6, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKLMPKFEQHRTDFAYCQTITKRSSSAFYTAFSQLPLERAWSIY
                     AVYAFCRTADDLVDVDHDIDGLMALRQSLTTFANGHVPDHPMWRALAVVFETYDMNLDV
                     FFDMLTGQEQDATFKQPQTQQALEDYCYYVAGSVGLMILPMLATNPQSLVKPAVELGIA
                     MQLTNILRDVGEDYQRGRIYLPSKLLAHYQLNPTDLHGPIPSANFIRLWEHEAQIAMNK
                     YEAALTMMPQIDPVARPSLLAATLLYRELLLIAREQHYPILSQRIFLTDERKTQVLNQV
                     STKVHELALKEA"
     CDS             complement(5900..7138)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 377.8; E-value: 1.7e-114)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MKQVSIIGAGIGGLTAAVRLQKLGYNVTIYEQNAQPGGKMNQIVS
                     QGFTFDVGPTIVMMKDIYEEVFRFCGVDPHNYLPFEEVQPLMHLVFGDQSSLDLSRDLP
                     TLIAEINRIAPDDVNGMLNFLADIYHRYTIAKPNFLERSFRNWRDFYNLPALYAGLQLR
                     TFNNAYKNIAKFIKNENLRNSLAFQTLYIGISPYQGPSLYNIIPMIELFYGVYFLKGGM
                     YTVVNSLVKLFKEQGGTLKLTTPVQEIIIKDKVAVGIRVNNHPIHSDYVLCNADFPTAM
                     TTLIPNEQDRGQYTDQKIAKMDYSCSCLVLYLGLDKKYPTEALHTIHFAQDFSKNVADL
                     FDNGKLPEDPSYYVYVPSKMDPSLAPENSEALYVLVPVPELSKFNDWSPTTLKNYRQLI
                     INKLRQTATFSDI"
     CDS             complement(7745..8443)
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="LFYSFFDPTYLLVIIGLIISMAASGYVNRTFRHYDAYRSQSGTTG
                     TDAARFILSQSGINDVGVQKISGDLTDNYNGQTKILSLSEATADSTSVAAIGVAAHECG
                     HAVQDHVNYWPMRLRTALVPITNIGSSLSLPLIIIGVLLSYNQTLIHIGILLFSLALLF
                     QLVTLPVEFNASRRALQILSDGQVLTRDEVPMVRKVLVAAALTYVAAALSTFLQLLRLI
                     ILFGGNRDDN"
     CDS             8611..8778
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MEKTYRTKTYGEMPLKLDTGKGWIFPKGVEVKAHVDLETGQVSFF
                     IAPEDLDKMK"
     CDS             9267..10142
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MKHKLIERCFPNMTIKIVTDSSVQLTTAEIAQYNIKVVPLLVGFG
                     GDLIADTAVSTAEFDQQMAVSPVLPTTSQPPIGDFVSCYDELTADGSQVLSLHLTETLS
                     GTVNAARQAAKLASGDVTVIDTQAADRGMAFQVLTAARMAHAGADMATILAKITVIRQH
                     TKTYLFVDTLDNLVKGGRVPKLAGMVTNLIKLKFVFELEAGKLKLYTRGRGKKALIKAQ
                     EQILDQLADATRVEAAGISYVGEPSVAEAPEKLLQQVVPQVTPLVARTSPIIATHTGVG
                     AYALMFYTVD"
     CDS             10317..11045
                     /locus_tag="ctg22_11"
                     /transl_table=11
                     /translation="VSYLLNNPFFGIGLSILVYGIGEYLYHKTNRFVLFQPLFFGMLLG
                     IGLLVLIASILKAPVQKVYEAYQVGGDWLFWFVAPATVSFAVPLYKRNDIFKKHWDVIV
                     IALAIGLGLSLFGIYGISRLLGLTDAALGAMLVQAATTAIALPVAESVGGDQAIAAFAV
                     ILNSVLIYALGDHFIRWFKLHKNPLGAGLGFGIAGNAVGATKAIEVSEAAGATGAIAFV
                     IAGILVNFMVPGFAQLIGLG"
     CDS             11065..11484
                     /locus_tag="ctg22_12"
                     /transl_table=11
                     /translation="MKKGAFITQIVIYGLILLASSLIANLVNKIWPAFPMPTPLIGMIL
                     LYLLLTFKVVKLEQVAGVSNFFVQFISLIFIPSGIALVTKLDVLKAEGVQIVIVIIVST
                     LMLLLFTAGIAWVLIQVKEWFIARRTNSNVELEED"
     CDS             complement(11896..12447)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 83.7;
                     E-value: 2.4e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_13"
                     /transl_table=11
                     /translation="LKNMFVGPHVALAVPQPEDFDEISDWYTDADFVRKMDTAAARPLT
                     GEELERTYRNLDRNTEYYFHVHSLEDDHLLGFVTLFNIEWHNQVAQLAIAIGDPDERGH
                     GYGTETLSLILNYAFNELNLYKVCLDVIATNPAAIAVYQNSGFEFEGTNKRAIKRDGQR
                     IDLYHMGLFAADFQPRVTLN"
     CDS             12889..13743
                     /locus_tag="ctg22_14"
                     /transl_table=11
                     /translation="LRPLQVIQISDLHLTPHGQVPVHGQQYDPWGKLANIIDDIRRLPT
                     MPDLIVFTGDLIHDGSADDYQRLHAIVHTMEAEFDCHVRVILGNHDRRAAFYEGYLPAD
                     PGPYYASRMRIGNNDFYFLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPL
                     DGPTMTNMHYAILQNTPALLSVLRGHNLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYA
                     IDCHDLHHHYVHEGSSYQIITIDRGQVGVTTRQLLHGKAVIDELTIPDTKFVGRAPQGY
                     ESR"
     CDS             13798..14025
                     /locus_tag="ctg22_15"
                     /transl_table=11
                     /translation="MGLFRHHNQMPPRIKRKLKQRLLPVAAMEITATTIVVADVLTAKS
                     FRRGHRLGWLLLAFVQPFGPWLYFAFGQER"
     CDS             14220..14576
                     /locus_tag="ctg22_16"
                     /transl_table=11
                     /translation="MQRESELRQQAQEAIKGLIVRLSGWSDQSGDLLDIIDVLMQVDKK
                     ITTAKNPEALVNRLVNYIRSVAIKGRLHFPDEEEKLMIDLGIIGQKAGLNGAYMADFSD
                     KSQFYGMLEEVPQH"
     CDS             complement(14820..15302)
                     /gene_functions="regulatory (smcogs) SMCOG1266:hydrogen
                     peroxide sensitive repressor (Score: 127.1; E-value:
                     7.6e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_17"
                     /transl_table=11
                     /translation="VAEDMLTQALQQLKDHKIRVTPQRQIILNYLITHHNHPSVETIYQ
                     ELATQLPNLSLATVYNTLKLFVDLGIVIELQNGDAGTHYDFFGRPHYHVVCENCGKITD
                     VFEPDLRSVEAKAAELSGYLVTGHNMEVYGLCPDCQKLLNVTKTADLKRLKLTHSE"
ORIGIN
        1 tatgaaactg gtcacggtag ggaccaactt taaaaatcaa aggcgtaagc aaatgggacg
       61 agaaaccaaa attcggtttc tcgtcccatt tgcttataca gaggctagtt atgtcacagc
      121 ctcttttatt atgattaaaa cgtgctaaaa agatgggctg tttattcgtc agccgatgcg
      181 cgtcctattt cgacctccgg ggctggggac gattaatggc tatttttgag cttgataatg
      241 gcacggttta atcatgcttc atactaaacg ataactagcg caatgcgtgt aagtaccttg
      301 atttcagttc aagggaccaa atgttaggtg cgtcgcaatc agaccatacc caagtgccat
      361 atgacgctgt tctttgcgcg tgaggcgctg taattgggtg tgaacgtatt ggtagaggtc
      421 acgatgctgg cgtggtagag tcattgggac catatagtta cgataatagg cttgatatag
      481 ctggatggtt acttgctgtg gcgaaacgtt gttattcagg tcgattgcag ctgccagtag
      541 cgcttggcgg taggaatcgg atggttgatt ggtaatcggc tgattataag cagcatctac
      601 taaggtaaat aatttttgag catccacatc cattgttaga accaaccttt caatcgttga
      661 gataggcgca attatagcat ggtcagtatg cttgatgtgc aggcccgagt tggtttctaa
      721 agtaatggaa cgaacataac cagagccgcc aatgagcggg ggtcattggc ggctctggtt
      781 attaataagg gattaatcaa gcggcggtcg cagcagtgtt ttctgtttta agcccggtgc
      841 caagctgcgt agccgatggt tgggaaaata ccgatcaaac ggtcgatttg ttcacggtct
      901 aattgatatt cgatagctgg cagtagtgcg ttgacggcat cttcagcttg atcactgatt
      961 tcagtcacgc caacgagatg gccgtcttgg tcatggacct gtttactagc ggcaatcggt
     1021 tccttggaga cttgataata ccagtaatct gctaagtcat tatcactaac ggttaagccg
     1081 gctttttcag cggccggtat tttcatgcca gcttgcgcaa ttcgtggtga agtaaagacg
     1141 accgatggaa ttaccggata gtcaatggga gcactggttt gaccagagaa caaacgcatc
     1201 aagtatttgg actcaaagta ggctgcaggt gtgacctttg gcaagtcatt ggcaaggaca
     1261 tcaccggctg catagatgtt aggaacgttg gtttgcaagt ggtcgttgac ataaacgccg
     1321 tggtggtcat atttgacgcc aatccggtct aagcctaagc catctaagtt tggaattcga
     1381 ccagtcgcat ccaggatcca gtcggtcgtt aattgctggt ggtcgccata actaacttgg
     1441 aactggtcat cctgtttggt aaatgcttgc acgttggcat ttttgatgaa ggttacccca
     1501 cgttcggtta agtcgtcaac cacttgtgca acgaatggtt ggtaaaaatc acggagggcc
     1561 tggtcgccat gtaacatgac tgtcacttgg gcaccggccg cgttagcgat ggtggcaaat
     1621 tccataccaa tatagcctgc gccaatgatg acgatacttt gtggtaaccg tttaaggttc
     1681 ataaaatcac tactatcgtg ggcgagcttg gtccccggaa tatctaaacg atggggcttt
     1741 aaaccagtcg caataacgat tttttcagcg gtaatgtttt gctgatcatc aacgacaacg
     1801 gtgtgagcgt ccttgaacgt ggcatgacca tgaatgatcg ttgcgccacc atcttccaaa
     1861 cgagctgtca ggcctgctgg taagggatca ataatctctt gtttatgggc cacgttggcc
     1921 gtccaattaa tggttggtgc actgctcaaa atatcattga ggcgtgctgc ttcccgcgtt
     1981 aatttgacag gttcatcaag agtgattttg gcgttacaac cacgattagg gcaggtgccc
     2041 ccaatcagac cactctcaat cacaccgacg cgaacaccag tcttggcgag tggtgcggcg
     2101 ccatcaaacg tggcgtgacc cgcaccaatg tataacacat cgtaatcgta tttgtttgtc
     2161 atgatttatc agcctccatt aaaattttgg taacttaagc ttaacgagtt ttaagaaacc
     2221 tgacaactga tatgaattgc tcgcgcccgc tgtaatgatt atactaaaag taattatgtc
     2281 aatagggaga cgttaatatg cacgctttga tcgcaattga ttcatttaaa aattccatca
     2341 cgagcattca ggccaaccga atagtggcta aacgatttgc ggctcacgga atcaccgcta
     2401 ctcaagttgc gattgccgat ggtggtgaag gaacggtggc ggcgtggctg gctaaccatg
     2461 ttggtggaca agctattacg gcatcaacgg tggatctggc gcaacggcca gtgactgcaa
     2521 cgtatggcta ctttgccact gaaaaaatgg cagtgattga ggttgcggct gcatccggaa
     2581 tccagtttgt cacgacgacc ttgacgccgt tagcaacgaa tacctatggg accgggctac
     2641 tgattaaaga tgcgattgag cgtggcgccc gtcagattat tctgggctta ggtggtagcg
     2701 gaacggtcga cggtggtgcc ggaatcctac gtgcgctcgg ttatcgtttt tgggctgccg
     2761 atggtcaaga gttagccatg actggcgctg atttaagtcg ggtcactaag attgacgatc
     2821 gacatgtgtt gccacaatta gctgaagtct cgttcattag tgcagcggac gtgacgaatc
     2881 cgctaacggg accgaacggc gcagctaagg tttttggccc acaaaaagga ttaccggttg
     2941 ctcaaattca ggctcacgat gccgctttag ctcactatat gacggtcgca gctggcgcgg
     3001 tgagtgccca cgaaggcgat ggggctgccg gtggtattgg gtttgcttta cgttactttt
     3061 tacacgcccg cgttcgctct ggttttcaat tgttagctga aatgagcaat cttaaaacga
     3121 aagtggccca agcggatcta gttatctctg gtgaaggcca agtcgacgat cagagtttta
     3181 tgggcaaggt accaattcag ctcagtcagt tagcccaagc ggccggcaag ccttgctatt
     3241 tattagttgg tcggcaaaaa ggtgcaaatg aaacatttgc caaacagggg gtcacggctg
     3301 ttttaccgat tgtcgatcaa gtcatgacct tagatcaagc catggcgcag ggaccagcca
     3361 atctggaacg gatggcggac cgcttagccc gaatcattag ccagtcataa aacaacttaa
     3421 gcggtcaaaa aaaccgtatg tgcagtgaat agcgcatacg gtttttcgac tgaattttat
     3481 ttatcaggaa catagtgatt caaaaaggct gtaacatgtc gttgatactc ggcaggatcg
     3541 atccaaaaac tctcggcgtg agtggcgttg ggaacctgcc acatctgctt ggggccctta
     3601 gcggcctgat aattttcttt gagcatccaa cttgggacgt agacatcctt gtcaccgtga
     3661 ataaagaaga tcggtagatg gttatgtttg agctgttcga cagaactgac gtcgcttaaa
     3721 taatagccca tacggtggcg gttaataaaa ctaacgatgg gcacaaacgg atactttggt
     3781 aagtgaaact gtcgctttaa taagtaagcg agttcttcct cgatactcga ataaccacaa
     3841 tcggcaatga tggccttaac ttgtgatgga aggtcttcgc cgctcatcat ttcaacggtc
     3901 gcaccaccca tgctgacacc aaaaaggatg atatccgtgt gacgaccatt gatacggacg
     3961 actttatcga tccagcctaa atagtcgcgg cgatcctgcc acccaaagct aatgtacttg
     4021 ccggcacttt gcccatggcc gcgatcgtcg ggcaagagga cgttatagcc catttgatgg
     4081 aacatataag cgtaatttgc catcgtttca ccatcacctt tgtagccatg ggaaacaata
     4141 acggttcggt tgctggttgt tttagcagga acgtactgtg cgacaaggtg attggcctcg
     4201 tcattagcgt tcagttgcca ctgttgaacg ggctgtcggt gtagccaatc gacataagcg
     4261 tagtaggcat cggcgtattt ttgtttatct gccgaagttt cgggcacgta atcaacacgc
     4321 ttgaaagcaa aatcgtagag cttctcactc gcgaataggg cggccgaaaa aattgccaca
     4381 ggagcactaa tcccggctac ggcgcgtgtt tttttcatta aatatcactc ctctaatctc
     4441 tcaataatat gatacgccga ttagaagtga gatgtaacta tattattcta gtaatataaa
     4501 aggccatcgc ggcgggcgat gacctataaa ttgcattggt cgctaggtgg catccccagc
     4561 gagcctgttt ttcattaact ttggaggagt aaatgaaaaa ggttcaagtg gctgaaggag
     4621 atgtccagtc actatatgtt tagtatagta gtttgattgt taaaaggtaa ctaaatcgct
     4681 tacttgactg gtgaaaaaac taaaaattat ttgtgggtgg tcaatattcc ggtatggaca
     4741 gatttcgtcg tgccaagtat gataccgatt caagtcgcat taagcctcct taagggctag
     4801 ttcatgcact ttagtgctaa cttgattaag gacctgtgtt ttacgttcat ctgtcaaaaa
     4861 gatgcgctga cttaaaattg ggtagtgttg ttcacgtgcg attagcaata attcacgata
     4921 aagcaaagtg gcggctaata gcgatggccg ggcgacggga tcaatttgtg gcatcatggt
     4981 taatgcagcc tcgtacttgt tcatggcaat ctgtgcttca tgttcccaaa gccgaataaa
     5041 attggcagat gggatggggc catgcaagtc agttggattg agctgatagt gtgccaatag
     5101 ttttgatggc aggtagattc ggccacgttg gtagtcttca ccaacatctc ttaaaatatt
     5161 ggtgagttgc atggcgatgc ctaattctac ggctggtttg acaagtgatt gcgggttagt
     5221 tgctagcatt ggcaaaatca tcagaccaac cgatccggcg acgtaatagc aatagtcttc
     5281 aagtgcttgc tgagtttgag gttgtttaaa agtcgcgtct tgttcttgac cagtgagcat
     5341 atcgaaaaag acgtcaagat tcatatcata agtctcaaaa acgacggcca gtgcgcgcca
     5401 cattgggtgg tctgggacat gaccattggc aaaggtggtc aatgattggc gcaatgccat
     5461 tagaccatca atatcatggt caacatcaac gaggtcgtcg gctgttcgac aaaaagcata
     5521 aacggcgtaa atactccaag cgcgttctag tggtaattgc gagaaggcgg tgtagaatgc
     5581 gctagaagac cttttagtaa ttgtttgaca gtacgcaaag tcagtgcgat gttgttcgaa
     5641 tttaggcatt agtttggtca tctttaatca actcctcaac ggctaattta gcactttgca
     5701 taacaatggg aacaccggcc ccagggtggg tgctactacc acaaaaataa agatggtcgg
     5761 catagtcgaa cttgttatgg ggacgataat aattactttg ttttaacgtc ggtcgtaagc
     5821 cgaaagtggc tccattatag gcgccaaact gttctttgaa gtcaaccggt gtaaactgct
     5881 tttcgacaac gatatgctgt taaatatcgc tgaaggtagc cgtttgtctt agtttgttaa
     5941 tgattagttg acgatagttc ttcagtgttg ttggtgacca gtcattaaac tttgagagct
     6001 caggaactgg tactaaaaca tagagtgcct cactgttttc gggagctaaa cttggatcca
     6061 tctttgatgg aacatagaca taatacgagg gatcttctgg taacttgccg ttgtcaaata
     6121 gatcggcgac gtttttgctg aaatcttgtg caaagtggat cgtgtgtaat gcttcggttg
     6181 ggtatttttt gtctagtcct aaatacaaga cgagacatga gcatgaataa tccattttgg
     6241 caattttttg atctgtgtac tgaccacgat cctgctcatt tggaatcagt gttgtcatgg
     6301 cggttggaaa atcagcatta cataggacat agtcactgtg gatcggatga ttattgacac
     6361 gaatgccgac agcaacttta tctttgatga taatttcttg aactggtgtg gtaagcttta
     6421 acgtaccacc ctgttctttg aataacttaa cgagactatt gacaactgtg tacataccac
     6481 cctttaaaaa atagaccccg tagaagagct caatcatcgg aataatgttg tatagcgacg
     6541 ggccctggta gggagaaatc ccaatataca gtgtctgaaa ggctaatgaa ttacgtagat
     6601 tttcattctt gataaatttt gcaatgtttt tgtaggcatt gttaaaggtg cgtaactgta
     6661 gtcctgcata cagagcgggt aggttataaa agtcacgcca gttacgaaat gatcgttcta
     6721 aaaaattagg cttcgcgatg gtataccggt gataaatatc cgctaaaaaa tttaacatac
     6781 cattgacgtc atcaggcgca atgcggttaa tctcggcaat taatgttggg agatcgcgtg
     6841 acaaatcgag actagattga tcaccaaaga caaggtgcat caaaggttga acttcttcga
     6901 atggtaaata gttgtgcgga tcgaccccgc aaaagcgaaa gacttcttcg tagatgtctt
     6961 tcatcatgac gatcgtcggc cccacgtcaa atgtaaatcc ttggctaaca atctggttca
     7021 ttttgccacc cggttgcgcg ttttgctcat aaatcgtaac attataacct aatttttgaa
     7081 gccgtactgc agcggttaag ccaccaatac cagcgccaat aatcgatact tgcttcatca
     7141 gtaaatctcc cccttaacag atgaataact aaaaagcatg gttaatcatt agttatattt
     7201 tggtttaata atgtaaaaag tacaacaaat atgattacta tgacgtatta aagtagtcgg
     7261 taggtgcgaa tagagcggac gagaaaaaca aaaaaaccac cgtatcgggg aatacggtgg
     7321 aaaaaggagt agggtaaaca tgtgacgggg aatcacatgt tactatgaat ttcattactt
     7381 tggaggagta aatgaaaaat tttaggttgt gttatagctg attgagttaa cctcaattgc
     7441 tatgatgtaa tcataccgag gttgtgtgaa gaatttgtga ctgaacatgg cgaatgtcat
     7501 gaaaaaaagg gaaaggcttt attaagaagt gtgaagaatc atcaacgttc ttacggaatg
     7561 ccttggcgag gtgcgatgat cgactgtttg gggccaaaga aaatagtcac ttcaaaagtt
     7621 gtcctttgaa gtgactattt tgattcgcaa tcaatgctag taataacaag tttgcggcga
     7681 cgctaagttg atagtgacca agcagatttt ggtgactggc tgtgggcact gccatttggc
     7741 gcgattagtt atcgtcacga ttaccaccga atagaataat tagtcgtagt aattgtaaga
     7801 atgttgacag ggctgcagca acataggtta aagccgccgc gacaagcact ttacgcacca
     7861 tgggaacttc gtcgcgagtc aaaacttgcc catcagataa aatctggagg gcgcgtcttg
     7921 aggcgttgaa ttcaactgga agcgtgacaa gttggaacaa taacgccagt gagaagagta
     7981 aaatcccaat gtgaatcagt gtttggttgt aactcaataa aacgccgata atgattagtg
     8041 gtaatgataa gcttgaaccg atgttcgtga tgggcacgag ggcggtccgc aagcgcattg
     8101 gccaatagtt aacgtgatct tgaactgcgt gtccgcattc gtgggccgca actccgatgg
     8161 cggccacaga ggttgaatct gctgtggctt ctgataggct gagaatctta gtttgaccgt
     8221 tgtaattgtc ggtcagatcc ccgcttatct tttggacacc aacatcattg ataccagatt
     8281 ggcttaaaat aaagcgagct gcatcggtgc cggttgtgcc agattgacta cgataggcat
     8341 cataatgccg gaatgtccga ttaacgtaac ccgatgcggc cattgagata atcagtccaa
     8401 tgatgactaa taggtaagtc ggatcaaaaa acgaatagaa caaggtcgac ccctcctaag
     8461 tggtttaatg ttaatccgat tctatcagat ttagcgtgac attcctactg aagaaagcca
     8521 ttggaaagtg tctttactat cgagaaacga cgtcagatta tataattagc ccagttaatc
     8581 gtaattggca aagagcgaag gagttttctg atggaaaaga cgtatcgaac caaaacgtat
     8641 ggggaaatgc cgttaaagtt agatactggg aaaggctgga tttttcctaa aggtgttgaa
     8701 gtgaaggcgc acgttgattt agaaacggga caggtcagtt tttttattgc accagaagat
     8761 ctcgataaga tgaaataagt attaggacca cgatacgcgg taaggttgag aagtttgttt
     8821 ctcgccttgg cgcgtttttt atggtggaaa ttggattggc aatgattatg gttaatacgg
     8881 tgttcacgcg tgagccacaa ctgcttgaag gcaataaaaa acctccgtat cggggaaata
     8941 cggaggaaaa gggaagtaaa tcggtaaaat gtaattaagt acacacacat cattacttgg
     9001 ggaagtaatc attaaagtta gggggtcgtt aaggattggg atttccttaa tgactataaa
     9061 cacagtatag cggcgacgcg tgaagaaagt gtgacgcgaa aagtttaaaa gcatgatttt
     9121 cagacgaaaa agttaggtca tggaacgaaa aaatatgacg atttttacaa agtttataac
     9181 gaaatgatga ccgtcataaa tcaatatgag tggctaaatg ctggtgtgac gcagttttta
     9241 ttggtcctag actctgaggt gctataatga agcacaaatt aatcgaaagg tgttttccaa
     9301 atatgacaat taaaatcgtc accgattcgt cggtccaatt aacgacggcc gagattgcac
     9361 agtataatat taaagtggtt ccgttactcg tggggttcgg tggcgacttg attgcagata
     9421 cggcagttag taccgcggaa tttgaccaac agatggcagt cagcccagtc ttgccaacga
     9481 ctagccagcc gccaattggt gatttcgtca gttgctacga tgaattgaca gcggatggta
     9541 gccaagtatt atcactacat ttgacggaga cattgagtgg gacggtcaat gctgctcgcc
     9601 aagctgccaa acttgctagt ggcgatgtga cagttattga tacccaggcg gctgaccgtg
     9661 ggatggcctt tcaagtgctt acagcagcac ggatggctca cgccggtgcg gatatggcca
     9721 caattttggc gaagataacc gtcattcggc agcatactaa gacctacttg ttcgtggata
     9781 cgctcgacaa tttggtcaaa ggtgggcgcg tccctaagtt ggctggcatg gtcacgaatt
     9841 tgattaaatt aaaatttgtc tttgaattag aagccggaaa attaaaactt tatacgcggg
     9901 ggcgcgggaa aaaggcgcta atcaaagcgc aggaacaaat tctagaccaa ttagcggatg
     9961 cgactcgagt cgaagcggct ggaatttctt acgtcggcga accgagcgtt gcggaagcgc
    10021 cagaaaagct tctccaacaa gtcgttccac aagtaacgcc actggttgcg cgtactagtc
    10081 caattattgc gacgcacacc ggtgttggcg cttacgcgtt gatgttttat acagttgatt
    10141 aaatttgacg aactaaccta ctattaaaaa ttactttgat gtgttataat taattaatga
    10201 taaatgagaa ccgtgttggt gcactgttct gagcctaacc accatttaat gatgactaga
    10261 cccggatggg gcaccttttt tgtcactctt ttcactaaaa gaaagtagga acttatgtga
    10321 gctatcttct caataatccg tttttcggga tcggactgtc gatcttggtg tatgggattg
    10381 gcgagtattt atatcacaaa acaaatcgct ttgtgttatt ccaaccgtta ttttttggaa
    10441 tgctgctcgg gattggttta ttggtattga ttgcgtcgat tctaaaggca cccgtgcaaa
    10501 aagtttatga agcgtaccag gttggcggcg actggttatt ctggtttgtg gcgcctgcca
    10561 ccgtctcgtt tgcggtgcca ttatataagc gtaatgatat ctttaagaaa cattgggatg
    10621 tcattgtgat tgcgttagcg attgggttag ggctgtcatt atttggtatc tatgggattt
    10681 cacggttgct tggtctgacg gatgcagcgt taggtgccat gttagtacaa gcagcaacga
    10741 cagcaattgc tttaccggtg gctgagtcgg tgggtggcga tcaagccatt gcggcgttcg
    10801 cagtcattct gaattcagtt ttgatttacg cgttaggcga ccattttatt cgctggttca
    10861 aattgcacaa gaatccgctc ggtgccgggt taggattcgg aattgccggt aatgcggttg
    10921 gtgccactaa agcgattgaa gtgagcgagg ctgcaggcgc aactggtgca atcgcctttg
    10981 tgattgccgg tattcttgtt aattttatgg ttccagggtt tgcgcagttg attggtttag
    11041 gttagatggt ccgggaggga ttcgatgaaa aaaggcgcgt ttattacaca aattgtgatt
    11101 tatggtttga ttttattggc tagtagttta atcgctaatt tagtcaataa gatttggccc
    11161 gcattcccaa tgccgacacc gttgattggg atgattctac tatacttgct gttaacattt
    11221 aaagtggtca aacttgagca ggtggcgggt gttagcaact ttttcgtcca atttatcagc
    11281 ttgattttta ttccatcagg gatcgcgtta gtaactaagt tagacgtgtt aaaggcagaa
    11341 ggcgttcaga ttgtgatcgt cattattgtt tcgacactaa tgttgttgct ttttacagcg
    11401 ggaatcgcgt gggttttaat tcaagtcaag gaatggttca ttgctcgtcg aacgaacagc
    11461 aatgttgagt tggaagaaga ttaaatcttg gtggcacata atttactcgt gagtagattg
    11521 ggtaccagtt ggatctaatc gaaacaggca gttgttgaac cgcttgtttt ggctattaca
    11581 agataatagc aggccgttgt ggggattgca tacccatgac ggctttttta gacggcaata
    11641 aaaaagccac cacatcagcg gatgtagtgg tcaaggagta ggaaacatca aagtgggggc
    11701 tttgatgaac cccattcatc agacttgggg gagtctatga atgaaagtga ttattagctg
    11761 cattatggca gcaacgcact aataatcgaa aaaactaaag aatattaagg attgacagtc
    11821 agttggtcac tttctatcaa tctgcgacta ttataattgc aaaagttatt ggctgcaact
    11881 aattgagctg attaattagt ttaaagtaac gcggggctgg aaatcagccg caaataagcc
    11941 catgtgatag aggtcgattc gttgcccatc acgcttgata gcacgcttat tggtgccctc
    12001 aaattcaaaa ccactattct ggtaaacagc gatagcggcg gggtttgttg cgatgacgtc
    12061 caaacagact ttgtaaagat tcaattcgtt aaaagcgtag ttcaaaatca agctgagtgt
    12121 ctcggtacca taaccatggc cgcgttcgtc gggatcaccg attgcgatgg ctaattgggc
    12181 aacctggtta tgccattcga tattgaatag ggtgacaaag cctaataagt ggtcgtcttc
    12241 taaactatga acgtgaaagt agtattcggt attccgatca aggttacggt aagttcgttc
    12301 gagttcttca ccggtcagtg gtcgggcggc agccgtatcc attttacgaa caaaatcggc
    12361 gtcagtgtac cagtcactga tctcatcaaa atcttctggc tggggaacag caagggccac
    12421 atggggcccg acaaacatat ttttcaaaat aatccctcac tcgtatgatg ttattaaagc
    12481 ttatcttcat ggtggcggca aaaggtgggc ttgtcaacca aaaattatga gattacgcgt
    12541 cagactagct agctcagtat gaaacacggg tggcatgtgc caagtgctga ggtcaagaac
    12601 aactagctct gggggacggc gaaataagat gcggatatac tgaagactta cagtaaagcc
    12661 gttgggcacg tgctgccgat aatgtggttt cagtataatg agggcaatac gggtgatggc
    12721 tgaactattg gtgaaaggtg ttgctgtggg ggcacttttc aatggtgcgt aaagagaggt
    12781 tagcacaaac tttacagtta ctttatatga agattggtaa aactttacgt tagctcgcta
    12841 tattagagat aaccatctgg tgattaaagt atgagaggga ggatcgaatt gcgtccttta
    12901 caagttattc agatttctga tctacattta accccccacg gccaagtacc ggtacatggt
    12961 cagcagtacg atccctgggg caagcttgcc aatattattg atgatattcg gcgattacca
    13021 accatgccag atttgattgt ttttaccggg gacttgattc atgacggtag cgctgacgat
    13081 tatcagcggc tgcacgcaat cgtccatacg atggaagctg aatttgattg tcatgttcga
    13141 gttatccttg gaaaccatga tcggcgagcg gcgttttacg aagggtattt gccggctgac
    13201 ccgggaccat actacgcgag tcgcatgcgg attggcaaca acgactttta ttttttggat
    13261 tcaaaggtta gcggttatga ggcaggctgg ttggcaccac aacagctaca atggttggga
    13321 aaacatctac gacaggcacc gacaaagcgg gcttttctat ttttgcatca ccccctagat
    13381 gggccgacga tgacaaatat gcactatgcg attttacaaa atacgccggc gctgttatcg
    13441 gtgcttcggg gacataattt aggcggcgta ttctctggtc acgttcactt tgtttcaagt
    13501 tatttgattg gagataatat tctgaatgtg gtggccggtt ctgcggccta tgcgatcgat
    13561 tgccatgatc tacatcatca ttatgttcat gagggcagta gttaccaaat cattacaatc
    13621 gatcgaggac aggtcggtgt gacaacgcgc cagttactgc atgggaaagc ggttattgat
    13681 gaattgacga tcccagacac taagtttgtc gggcgagccc cacaagggta tgaatcaaga
    13741 tagcgctttc ttaattaaca aggtataatg ttggtaataa ttaagggagg cgtcaatatg
    13801 ggactatttc gtcatcacaa tcaaatgcca ccacggatca aacgtaaatt aaagcaacgg
    13861 ttgttacccg ttgccgccat ggagattacc gcaaccacaa ttgtggttgc ggatgtcttg
    13921 acggcgaagt catttcgccg aggacatcga cttggctggt tgttattagc ctttgtacaa
    13981 ccatttggac cgtggctcta ttttgcgttt ggacaggaac gttagggtaa ttagtaaatt
    14041 aaagtggggt taagttcggg tgaaagctcg gactttttta cgttgatggg cgttttttga
    14101 acgtttatga atgttttttt gaatgcaatc ataagcgtgt ataataaaag tgtatataaa
    14161 gatacctata atttgaaatt attatggtaa tccgaatcat atagaggggg actttattaa
    14221 tgcagcgaga atcagaatta cgacaacaag ctcaagaggc tattaaggga ctaatcgtcc
    14281 ggttaagtgg gtggtctgat cagtcggggg acttattgga tattattgat gtattaatgc
    14341 aggtcgataa aaaaattact acggctaaga acccagaagc cttagtcaat cgtctagtaa
    14401 actatattcg tagtgtagcc attaagggac ggttacactt tccagatgaa gaagaaaagc
    14461 taatgatcga cttaggaata atcgggcaaa aggccggatt gaacggggcc tatatggctg
    14521 atttctctga caagtcacag ttctatggca tgctggaaga agtcccacaa cattaatacc
    14581 ggccaggggg ttgagggtta ccggtcgtgt aattgctgat tggtattccg aaagcgtcct
    14641 ccgattgtga tgctgattaa agcgtaagta aaatcagctt atcgtataaa ttaaaaggaa
    14701 cacttcaggc tgtgatagtc cgcttaaggt tgacagggac taatacagga aaactgaaag
    14761 tgttcctttt gttttaggat aaccagcgcg ctaaatagcc ggttgtcatt gaactggttc
    14821 tattcactgt gcgtcaattt caatcgcttt aaatcagctg ttttagttac attgagtagt
    14881 ttctggcagt ctgggcataa tccatagact tccatattgt gacccgtaac caagtaccca
    14941 gagagttccg ccgccttggc ttcgacactg cggaggtcgg gttcgaaaac gtcagtaatt
    15001 ttaccgcaat tctcacaaac gacgtgataa tgtggtcgac cgaaaaagtc atagtgggtg
    15061 ccagcatcgc cattttgtaa ttcaattacg attcctaagt cgacaaaaag ttttaacgta
    15121 ttgtaaactg ttgccaagct caggttaggt aattgagttg ctaattcctg atagatggtt
    15181 tcgacggatg gatgattatg gtgagtaatc aaataattaa gaatgatttg ccgttgcggc
    15241 gttacacgga ttttatggtc ctttaattgc tgcaaggctt gggtcaacat atcttctgcc
    15301 acgacgcggt tcctcctttt atcatattca cccttattaa accacacttt ttagaaggat
    15361 tccaatttag aaacattact agataaaact tttgacaaaa ttaattaacg aaatagctga
    15421 aaaggcttta ctggggctga agacgtgagt aaactaacga taattaagtg catgttgatg
    15481 ggggtggtaa aatgacacaa ttaattgtac cagcattacc ggttgagcgg gtccaatacg
    15541 aacgcgcata tgtacttggc cttgaagcaa tgatgaaagt tatccggcaa cttacgacta
    15601 cggaaaaagg acggcaagta cccactaatc agttcccagt atttgcggcg agctatgatg
    15661 t
//
