LOCUS       c00113_JAJQWP0..       12436 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJQWP010000053.1 Lactobacillus helveticus strain NBIMCC 8269 (179)
            NODE_53_length_12436_cov_296.524271, whole genome shotgun sequence.
ACCESSION   JAJQWP010000053
VERSION     JAJQWP010000053
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 18:34:46
            Original ID  :: JAJQWP010000053.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12436
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12436
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6821:9717]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6822..9717
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12436
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12436
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(49..843)
                     /locus_tag="ctg113_1"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDT"
     CDS             complement(971..1954)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg113_2"
                     /sec_met_domain="PLDc_2 (E-value: 1.4e-27, bitscore: 86.4,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKEAAANGAKVRVIYDTSGSRGTKPSFFDHLRELGGEAQPFISTS
                     KKHWFTTPRLNDHLHRKLVIIDHHIGYIGGFNIGDQYVNKSPKFGHWRDTHLRVIGQSP
                     ILMEVRFAMDWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQLFPQDLIINITA
                     SDEAEGIIAGAKKYIYIQTPYLIPEESILEALIIAANSGIDVRIMVPCMPDHPFVYRAT
                     EYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNISSVGSANQDFRSYTLNFEVNSFNYNP
                     ALTQELKKIFEKDLDKCTLLTNDYFAQQSSWLKFKQYFSRLLSPIF"
     CDS             complement(2005..2457)
                     /locus_tag="ctg113_3"
                     /transl_table=11
                     /translation="MILTWDIIRRTIEVLWIINIAFAVWTVFRSRRSVVATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQRDMLKEHDLLPEKERLPRV
                     RMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKMPKNLSA"
     CDS             2600..3097
                     /locus_tag="ctg113_4"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVT
                     NY"
     CDS             complement(3165..5438)
                     /locus_tag="ctg113_5"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKGLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRNGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSNLSDLTDKDVLALAGSATDKRNTGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYFFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLVYQPV
                     MKNR"
     CDS             5567..6421
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     73.6; E-value: 3.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg113_6"
                     /sec_met_domain="LysR_substrate (E-value: 4.4e-31,
                     bitscore: 98.0, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 8.6e-24, bitscore: 73.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKLKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             6494..6712
                     /locus_tag="ctg113_7"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKELKKSMTILPTLWKNREFMSFI"
     CDS             6822..7232
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_8"
                     /sec_met_domain="Amidinotransf (E-value: 2.6e-26, bitscore:
                     82.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEIQNATPSLADLAEDPDYPFYL
                     DPMLNVYFTRDQQAAIGNGMTINRMTSRARRRESLFMETVLKHHPDFKNANIPIWRDRY
                     THGRLEGGDELILNNHVFSNRYFSNNFRCRNH"
     CDS             7180..7734
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_9"
                     /sec_met_domain="Amidinotransf (E-value: 3.1e-49, bitscore:
                     157.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQITSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFILDKSGKIDIYVLEQDDHGEIKITPETDLIKVLKNYLHLSE
                     IDLISTGGGDAIAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSS
                     ELSRGRGGPRCMSYPLVREDL"
     CDS             7746..7883
                     /locus_tag="ctg113_10"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPTELNYLIDFALHLKELKKIFRMNI
                     "
     CDS             7982..8590
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_11"
                     /sec_met_domain="OTCace (E-value: 1.4e-37, bitscore: 119.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 6.1e-26, bitscore:
                     81.4, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDVIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLTLAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHD"
     CDS             8785..9207
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_12"
                     /sec_met_domain="AA_kinase (E-value: 5.6e-13, bitscore:
                     39.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKPIGPFYTFNEMQR"
     CDS             9376..9717
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_13"
                     /sec_met_domain="AA_kinase (E-value: 2.4e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             9734..10270
                     /locus_tag="ctg113_14"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             10391..11557
                     /locus_tag="ctg113_15"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLIKKILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHIDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             11573..11734
                     /locus_tag="ctg113_16"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLNVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             11737..12342
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg113_17"
                     /sec_met_domain="LysR_substrate (E-value: 7.4e-19,
                     bitscore: 58.1, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDVVIKDFILLAKKVY"
ORIGIN
        1 aaactattga gttttcaagg cttcatagtt ctttttggtg tgggaagttt aagtatctaa
       61 taatactaat ttgctttttt taacttgagt tagccagtta ttgaaaaatg ttttctgagt
      121 atctttccat tgaaacaata gatttgataa tgaataattt tctggcttct tataatgtcg
      181 ctctggatgt gcagcaatct ctctttcata ttctttttta aggccttttc ggccatattc
      241 gatatgagag aaaataaaat tttgctcagg cttttctaaa gaagagacca taaatagatg
      301 cccattatcg tcaactgaat taatggttaa tcgtggatct tgcataatct gtgttttatc
      361 catttcagcg taacgagcat gtggagcgat aaatcctttg ctgagtccat ttaataaagg
      421 atgtggttcg ataattaaat gaggaaaaac accaaagatt tttttcgata aaattctttt
      481 ttgaatattg taaaaataat ctaaagcggc cattgcaccc cagcaaaaat ataattgctg
      541 caacttgtat ttatctaata gttggagcaa acatcggact tcctcgatgt aggtaacttg
      601 atcaaaatca agatgatcta aaggtgcgcc cgtaatgata aagccatcaa actctttgat
      661 ttgattaaga tctaatggct gggaagtttt tgcaacttca ggtgggacag gacgattttg
      721 ataatgcata cgtggataaa agaaagtcag gtctgcatct ggcaaaacgc gtgcaaatct
      781 ttgttgagta tctaacttat cgtgcattaa attcaaaacg cctattttta ctctattagc
      841 caagttttat cctccttact ttttaatagt tatcattata taacctataa aaaataagta
      901 aagaaataaa actgcatttt taaaatacaa agtaaaaccc ctatcggata aaccgataga
      961 gggcttttca ttaaaaaata ggtgataata atcttgagaa gtattgctta aattttaacc
     1021 atgatgattg ttgagcaaag tagtcattag ttaaaagggt acatttatct aagtccttct
     1081 caaaaatttt ctttaattct tgagttaaag cagggttgta gttgaatgag tttacctcaa
     1141 agtttaatgt atagcttcgg aaatcttgat tggcggaacc aactgaagaa atattagaac
     1201 cgctaaccat agtttttgca tgaataaaac catcattata tttgtatact ttaacgccat
     1261 gggctactaa atacttagca tagtattctg tagcacgata aacaaatgga tgatcgggca
     1321 tgcaaggaac cataattcga acatcaatac cgctgttagc agcgataatt aaggcttcaa
     1381 gaattgattc ttcgggaatt aaataaggcg tttgaatata aatgtatttt ttagctcctg
     1441 caataattcc ctcagcctcg tctgatgccg taatgttgat tattaggtcc tgaggaaaca
     1501 attgcatagc gacattttta ttatcattga tatcttttcg attgacagta aatggtttaa
     1561 gttcctttaa ttcaaattta ggtaaatttg ttcttctgat tgacgtgttc cagtccattg
     1621 caaaccggac ctccattaga attggtgatt gcccaattac acgtaaatgg gtatcccgcc
     1681 aatgaccgaa ttttggtgat ttattgacat attgatctcc aatattaaat ccgccaatat
     1741 agccaatatg gtggtcaata ataactaatt ttctatgtaa gtggtcattg agtcgtgggg
     1801 tagtaaacca gtgctttttt gaagtggaaa taaatggctg agcttcgccg cccaattctc
     1861 ttaaatggtc aaaaaagctt ggcttagtgc ctcttgatcc agaggtatca taaattactc
     1921 ttaccttagc accattagct gcagcctctt tcaaggcttt taaaacacga tgccctaatt
     1981 ggttagaata aaaagtataa aattctaagc tgacagattt tttggcattt tgatatcagt
     2041 aatcatttgg tcaaaaagtt ctggtccaga aataaatact ttgacctgat tatcaaaagt
     2101 taaaatcgca tcatcgttgt taagatttag ttccgaaagc attcttactc gtggaagacg
     2161 ctctttttca ggtagaagat cgtgctcttt aagcatgtcg cgttgctcag ctaaataatg
     2221 tctttgtacc tttttttgct cttcttgaat agcaaagatt tcatcatgtg aaagctgacg
     2281 accaaagaaa agatatagga taaaaccgat accgggcaga acggttaata caagcatcca
     2341 tgcccaagtt gcaacaacgc tgcggcgact tctaaagacc gtccatacag caaacgcaat
     2401 attgataatc cataagactt cgatagtcct acggattata tcccaagtta aaatcatgaa
     2461 ttaagtagtg ttataaataa ttttagcaga attaagcaaa tagttataaa acagatgagt
     2521 aaaaaatgct tccaattcga taatttttga taaaataagg gatggagaat ggtataaaca
     2581 ctacgggggg tggattatga tgagaaaaca aattatttct gctgcaggta taatgttagc
     2641 agttattgga ttaggcgcag caactacaca aagcgttgat gcagttgtta ctaatccagt
     2701 tagacaaggt aagagattaa atctaactag aaatgctact gtttataata gacatggtgt
     2761 taaagttgga catttaagaa agggaaagct ttacaaagta cgtgccataa aagtaattaa
     2821 tggtaatact tatgtaaaga ttcgtaaaaa tagatttgtt aaggaagaag ccttcttgcc
     2881 atatatgaag actactgtaa aagtagttaa tagaatcaaa aagcattcct ttgtttatga
     2941 tgagaatggt gaaaaaatcc caggcaaatt tttaaagcgt ggtgctaagg ttaactattt
     3001 aggccataaa gaaattaatg aaaaaccatt tatcaaaatt gctgatggtg aatatgttaa
     3061 ggctttgaat gccttgacta cagttactaa ttattaatca aaaaaacact ctgaaaacta
     3121 cattgtagta atttagtttt cagagtgttt ttgttttaag ttaattatct gtttttcatt
     3181 actggttgat aaaccaaatc aataataatt gctgcaatta atgcaaccac aacggtaatt
     3241 aataagtttt gccaactaat ttgagccatt gctaaaccgc ataaagctaa aataaaggtt
     3301 aatgcgacat cggcaatttg aacaatacct acaagtttag atgggtaatc ttgccagaag
     3361 tatttacgag ttctagtaat taatacaatt aacattgcac ttagaactaa gtaaacatag
     3421 accatggtag agatagaatt gtgactccag ccatgcatgt tgaggtagct gaaaaaagcg
     3481 ataccgataa ctgtccaacc tgcagcaaga gagaatgcga ttttggctaa ccttgccata
     3541 ttccaatttt ctggtttgta agtaatatgg gtacggtcgg taccaatcat catggtaacc
     3601 atgttattca tgattgtgta aataaccata gcatttaatg ccattggaat atagttgaag
     3661 aagaaatagc cgaaggttaa aagcatagtt aattcggcgg ttctggcgag cttagcaagt
     3721 gaccaagtag tcattcgttg atatacacgg tgaccagcat caagaatttt aacaatagag
     3781 cttaagccat catctagaag caccatctta cttgaacgct tggcaacatc ggcagcgtta
     3841 gaaacagcaa taccaacttc agcttgcttt aaagcaggag agtcgttaac accatcacca
     3901 gtcataccaa cgatataacc tttttcttgg aagaatttaa ccatcttaag tttatcttca
     3961 ggtaaaacat cggcaattcc tgctaattca tcaatatcgg tgctttcatc aaagtcatga
     4021 atagagataa cgttaccagt taaatcaact tgttcagcga ctgctgcggc agttctttga
     4081 ttatcaccag ttaacatgat tggacgtacg ccccgttttt taagttctgc taaagcagcc
     4141 ttagagtcct ttcttacttt atcttgtaag ataaatactc ccgcaagttt gtcatcaatt
     4201 aacacggcaa ctgagcgtcc agctttaaaa ttgatgcctt caactgcttc atttgcattc
     4261 ttatcgatta atgaaagttg cttaaatgaa cctaacttaa cattgtgacc atctacttca
     4321 gccatagaat agccagtgtc agaagtaaat ggggtgaagt gttcaacgtc catgacaggg
     4381 atattgtttt cttttaagta ttcatcaatg gcgatatcaa tgatacctgt attgcgctta
     4441 tcagttgcac taccggctaa agcaagtaca tctttatctg tcaaatcgct taaattgctc
     4501 caactagcaa ctgcagtttt gttttcagtg attgttcccg tcttatcaag taaaagcaag
     4561 tttaagttag ctgcatcttg gataccagtt aaatcagctg ttaagacgcc ttctttactt
     4621 aaacgggttg cttcaaatga attggacaat gcaaaggttg acggcatcgc aaccggaatt
     4681 gaagcgatga acatcatggc taagaatggc aacatgttga taaacgtatc aaaattacca
     4741 cccttaaaga atgaagcaat gataataact aaggtaagta caccgtcaag taggcaaagg
     4801 tagtaaataa tcttagttaa aagttgttgc aagtgaccag gtgcagctga attgttgatc
     4861 aagttaatag tcttaccatt tcttgaatct ttaccagttg cagtaacaat tgctaatcca
     4921 tcgccttcaa caacagtagt accagcataa gctgtgtcat caatgttctt tttaacgggc
     4981 ttagattcac cggtaattga gctttcatca caggcgatct taccgctaac catttttaca
     5041 tcggctgcaa gtacatctcc acgttgaagt gagattaagt cgcctctaac taattgctta
     5101 gagtcaattt tgatccactt accatcgcgt tctacagcca ccttaggggt tagcttatgt
     5161 gaaatggtat ttaatacccg ccgtgactgt ttcttcttgg atgcaccgtt aaaagccgca
     5221 aaaagaagca tcaacaagac gaacaaagat tgaatccatt tgcctaagat acattcgagg
     5281 attaaggcac cttctagaac ccaggcagaa agattccata attttgatag aaattcctta
     5341 aaaaagttgt attcgggttc aggtgcttcg tttaacccat cttccttaag tcccttatct
     5401 gcttcggctt gagttaagcc atgaaatttt tcagacattt tattccctcc aaatctacct
     5461 taataaagta gcacatatgt tgtttgaatg aaaatactaa attaaaatat aagatataga
     5521 attttttaat aagagataca actaaaataa aaaagataga ttattaatga atattaaaca
     5581 attacgctac tttttagtag tagccgaaga aaagcaaatc acttcagcag ctaaaagact
     5641 atacattgca caaccgccgc tgagttatca attaaagcaa ctagaaatag aactaggagc
     5701 acaattattt aagcgtactg ctcatggaat tgaattaaca gatgctggac aaattttgca
     5761 gagctatgct agtgaaattc tctctttatc agaaagcgtg aaaaatcagg ttcataaaac
     5821 tgtttcaggt gaactaggca cgattgcaat aggcatggct tcatcatcaa ctggactaat
     5881 tcctatgaaa agttttcaag atttaactaa gttttatccg gaaatcaact ttgatattta
     5941 tgaagataat acctttggca ttatcgataa attggaaaag aagacaatcg atttaggaat
     6001 tgtgcgtacg ccttataatc gtaatggctt aaatgcaaaa actttaacta ctgaaagaat
     6061 gatggcagtt actgttgatc ccaaattaaa ggataagacg gaattaagga ttaaagatct
     6121 aaatgagcag cccctcatta tttatcgaag atttgaagaa atttttaacc agacttttgc
     6181 tcatcatggg attaagccgt tttatgctgt taaatgtgat gattctagaa cagcgattac
     6241 ttgggcgaag agaaaaatgg ggattgctct tgttcctgaa tctattgctt ctacgtatgc
     6301 acctgatgat cttattccta ttaaacatag taattggatt acgcatttgc aattagtgtg
     6361 gcgcaaggat caaaaggtga cgcctttaat gaaaagaata atagattcat taagccgtta
     6421 agattgtaac ttctacctaa ttgatccata attattgtaa gcggatatat aatttgaatt
     6481 aggagacgct ataatgactg acttaattca tgtttattcc gaaattggca aattagaaac
     6541 agttatgctg catcgaccgg gaagagaatt agaaaatctt tcaccggata tcttaaatcg
     6601 aatgttaatt gacgatattc catatttaaa aatagctcaa aaagagctca aaaagagcat
     6661 gactattttg cccacacttt ggaaaaatag ggagttcatg tcgtttatct agaagattta
     6721 ttagctcact ctttgactaa tgaagatgtc cgtacaaaat ttgtagatca attattagaa
     6781 gaatccaata taaaaaagaa gatccattac atcaattact gatggactat ttaatagcaa
     6841 tgccagtaaa tgaaatggtt aagcaaataa ttgctggtat tagaaaaaat gaaatacaaa
     6901 atgcaactcc ttcattagcc gatctagctg aagatccaga ttatccattt tatttggatc
     6961 caatgctaaa tgtgtatttt actcgtgatc aacaagcagc tattggtaat ggcatgacta
     7021 ttaatagaat gacgtctaga gctagaagac gtgagtcatt atttatggaa accgttttaa
     7081 agcatcatcc cgactttaaa aatgccaata ttcctatttg gcgtgatcgt tacactcatg
     7141 gacgtttaga aggtggcgat gagctgattt taaacaatca tgtttttagc aatcggtatt
     7201 tctcaaataa cttccgctgc cgcaatcact gaccttgctc atagcctgtt tggtcattct
     7261 agttatgaca caattttagc aattaaaata ccacataatc atgccatgat gcatctggat
     7321 acagtcttta caatgattaa ttatgatcag tgtaccgttc atccttttat tttagacaaa
     7381 tcaggaaaga ttgatattta tgttttagag caagatgatc atggtgagat taaaattacc
     7441 ccagaaactg atttgatcaa agtgttaaag aattatttgc acttatcgga gattgaccta
     7501 atttcaaccg gaggtgggga tgcaattgca gccccaagag agcagtggaa tgatggctcg
     7561 aatactttgg ctattgcgcc aggtgaagtc gttacatatg atcgtaatta tgtatcaaat
     7621 gatttgttaa gaaagcatgg cattttagtt catgaaattc attcaagtga gctttctcgt
     7681 ggccgtggag gtccaagatg tatgtcatat ccacttgttc gtgaagattt gtaagaggcg
     7741 tcaaaatgaa atatttacaa aatgtgtttc aaggcagaag tttattaaaa tgcaaagact
     7801 atactccaac ggagcttaac tatctaattg attttgcact tcatttgaag gaactaaaga
     7861 aaatattccg catgaatatt taaaaggaaa gaatatagct cttttattta aaaaatcttc
     7921 aacaagaaca cgttcagcct ttgtagttgc atgcaatgat ttaggcgcaa accctgaata
     7981 tatgggtgct ggtgaaattc atttaggtaa aaaggaaagt attgaagata ctgcaaaggt
     8041 tttgggcagt atgtttgatg tcattgaata tcgcggtttt gctcaaaaag atgtagaaga
     8101 tttggctaaa tattctggtg tccctgtttg gaatggttta acagataaat ggcatccgac
     8161 ccaaatgttg gctgacttta tgactattaa agaaaagttt ggacatttaa aggtacttac
     8221 tttagcttat gtaggcgatg gacgtgataa tgttgccgac agtcttttag tggctggcag
     8281 catgcttgga gttaatgtac acatagttac gccaaagcct ttattcactc accctgatgt
     8341 acaaaaaatt gcagaaggtt ttgccaaaga ttctggatca agaaatttga ttactgatga
     8401 cattgaacaa ggcgttaaag gtgcaaatat tatttatact gatgtctggg tatcaatggg
     8461 tgaaaatgac tggagtgaga gaatcaaatt gttaaagcct tacacggtta caatgaatat
     8521 gatgtatatg acaggcaccc cggatgatca actaatcttt atgcactgtt tgcctgcgtt
     8581 tcatgattga actgctaaag ttggcaaaga aatttatgaa aaatatggtc taagtgaagt
     8641 ggaagttaca gatgaagtct ttaactctca atacgcttgg caatttactg aagcggaaaa
     8701 tagattgcat tctatcaaag caataatggc cgctactttg ggcaatttgt ttattccgtc
     8761 agttgatgaa ggaagtaaat aaagatgaaa agaatagttg tagctttggg tggcaatgct
     8821 attgaagcag gtgataatag tgcagctgcc caagaaaagc aggttaaaaa gacaatgaag
     8881 gttgttgcta aaatgattga aaatggtgat caggtagcga ttgttcatgg taatggcccg
     8941 caggttggta atttgctttt gcaacaatac aaaggttcaa gtaaagataa tctcgctatg
     9001 ccgcttgata cagtagtatc aatgactcaa ggcagtatcg gctattggat gcaaaaggcc
     9061 ttagacgatc aatttaaaca tacaaattat ccacatcaag ctgttgcttt aattactcag
     9121 ataatagtta atgcgaatga tccaactttt aagaatccaa ctaaaccaat tggcccattt
     9181 tatacattta acgaaatgca gaggtaaaaa atctatcatc ctgaatatac ttataagcaa
     9241 gatacaggtc gaggctatcg tcaagtagtt tcttctccaa agcctgttaa aattattaat
     9301 gcaccaggca ttgacacttt actaaagagc aagtttgttc ctattgctgc cggaggtggt
     9361 ggaattcctg ttgtagtgaa agacgatagt ttgcaaggcg tagcaggagt aattgataaa
     9421 gacttcagtg ccgcaaaact agctgaagat attcaagcag atgaattagt tattctaact
     9481 accgttgaca atgcatacgt gaactataat caacctgatc aagctcctat tggaaaaata
     9541 aagattgatc aattaaagaa gtatctagaa gctggtcaat ttgctgcagg cagcatgaag
     9601 ccaaaaattg aagctgtcat tgatttcgta gagaaaacag gaaagactgc aattattact
     9661 tctttaagaa atgcaagtaa acttgatgat ggagtaggta caattgttta taattaactg
     9721 cggtgagata taaatgaaca tttttcaaga aggaaatccg caaaatattg ctcaggtatt
     9781 agctggaaaa gattatcgtg tagctttgca gcaagctatt tttaaaaagt atcctgatgc
     9841 gactttggtt gatataaact taaatatccc ggggccaatt aaaaataatc gatatttaat
     9901 caaattattt gattacggaa ttaaacaatt agaagaaata tggcagaata agggatatga
     9961 ctataaatta gtaaaagcat taaataatga tgctggatgt gaaaatttct atgttttgcg
    10021 agaatctagc aaagtagtta aattatctac aattttattt gaagaaaata ataaaatagg
    10081 acgattattt gatgccgatg tattaattaa agggaaaact gcactttcac gccaagagct
    10141 tgaatactct agtcgccgct gctatttatg caatcgccct gctaaagagt gtgctcgatc
    10201 acggcgacac tcagtagaag agatgcaaag atacatttct agtttatatg cgaagtatgt
    10261 aaataattaa aacgggatgg gaggctaatc atcccgtttt ttcatttaaa tcttaaaaaa
    10321 agctaacgaa aaatacataa aatgttctaa aatataagta aagttatgaa tatatattgt
    10381 aaggaaaact atgaaattaa agaaaaacca agacaattta aaacaaattg cttcattgat
    10441 tgaatatgct tttttaaaag attctgattt gactacagat agtaacttta tgccccgata
    10501 tgatcatagt gatggatatg gatattttga tcaagaaaaa ttgaccagtt atatgatggt
    10561 caataagttt aaagctgaga tatttggtca tcatgttcca ctggcaggta ttggttatgt
    10621 ggcatcatat cctgaataca gaggacgtgg acatatatct aaattaataa aaaaaattct
    10681 ttttgatttg catgatcaaa aaatcccagt tgccaatcta gctccatttt cagaaaaatt
    10741 ttatcgtcat tatggtttta gcaatagtat ttaccaaaaa gaatatcgct tttcgggagc
    10801 tgcacttgct tctttcagat taccacgcaa aggtaagata attcgtggaa aatggaatga
    10861 tttgattgtt caaaatggtg tgattcaatt atatgaacgt cagttgcata ttgacgatga
    10921 aagaaatacg atcatcagag aagcttggtg gtggaataga ttagatgatt attatcatca
    10981 tcgagagatt gctgtttact tcgatgaagc tggtcggccg atgagctact tgatttatcg
    11041 cataattgat aactgtttta tggctgatga attatattca attacgcctc aaggattatt
    11101 aagcatatta ggctttatgg cagctcatat agggtcaatt aaagagtttt gtatgacatt
    11161 gcctgagaag tctttattgg ctgaactttt tccagagcaa aatgaattgg atattcaact
    11221 tcatccatat atgatgagta gaattattga tttccaaaaa gtcttgtcat gcatgcgccc
    11281 attgcaagag ggtactttta acatcgaagt taattatgat gatcagtgtc catggaatat
    11341 tggcgtttgg caattaacta attatgatca ccaagttaag tgtgaacgaa aagaagatga
    11401 actagttgat ttctctggtc caattacaac atggactcaa atcttattag gacgtttaac
    11461 tatggaatcc gcaattaaac ttggtttgat cacagattat cgaattaaaa agttggactt
    11521 tgtaaaaggt aaagtctcat tttatgatta tttttagaag aaggtatcca aaatgagtaa
    11581 gcaaaagaaa gttagattac taaaattttt aaacgtggta gttagtggaa taaatgtggt
    11641 tatttcgcta ttgattatgt tcaacaaata tcaaattaga aaagataaaa aacaaatatc
    11701 agatgaaggt catgccccat tggatgaaaa ttaactatga aaaaattgag aatagcatac
    11761 tttaaccaac ttggtagaag acaattagat cgaattgtag accaatttaa gcaaaaacat
    11821 tctgatgtag aaattgaatt aattggaatg ggacacgatg aagcttttga taaattagcc
    11881 aaaaatgaag ttgatttagc gattagtgat ttgcgcgatg atcagctcga ttttaagaaa
    11941 gaaatcttag gtcaggaagc agtaatggct attttgcaaa agggtagtta tcctagcggt
    12001 gttcagatga tcaataaaga tgatctagct gatttaacct gttttattgt agctaagcct
    12061 gaagaagagg ctgcagaact ccatttattt aaagatattt atcagattag aagcccattc
    12121 attgcttcaa attccgtaga agaggcagca ttgttagtag cttctggatc aggatatttt
    12181 ttaatgaatg aagcaaccgc cagtttaatt agtaatgata ctttacaacg attgttttta
    12241 ttgtctaatg gacaacaaat gtggcaaaag attgcagctt tttataccaa tgaagatgta
    12301 gtaattaaag attttatttt gttagctaaa aaagtatatt aatctatctt ggaacagcaa
    12361 aatactgtaa aaataaaaat gcgctgattg taaaattaaa ttgaacactt gataaaaaat
    12421 aaaaagtcca ttcgga
//
