LOCUS       c00002_JAJTJS0..       17782 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJTJS010000011.1 Lacticaseibacillus rhamnosus strain ICIS-627
            NODE_11_length_105926_cov_246.575478, whole genome shotgun sequence.
ACCESSION   JAJTJS010000011
VERSION     JAJTJS010000011
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 05:34:14
            Original ID  :: JAJTJS010000011.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3322
            Orig. end    :: 21104
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17782
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[8322:16104]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..12782
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..17782
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17782
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1603..2958)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MKAKDNQADRGDQPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLPKSGVNTDKLDALERFVRHFDKEYATQTVRDIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPIEMVCCFVGAGIGNWLREIMIRRNWTLLACIGVSVAVACLVYFIAF
                     RGLEMGLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMVVHLRPENFVDLGLSPILLLVYRLIASFCGVFGFSVMFNSPRRMAIQAGL
                     IGAVANTLRLELVDLNTIPPAAAAFIGALVAGLIASAINRVDGYPRISLTVPSIVIMVP
                     GLYIYRAVYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRQSD"
     CDS             complement(3138..3491)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MDYEEELETKGYIDCLLHELHEQPQLIRQTNIEEVVERTKEEIIR
                     DGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDELRRIANGQKKEDPRRFLRI
                     RHFLAQRFQHHMQ"
     CDS             complement(3609..4988)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLPSRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQNYHVKASASGVLHLETALAGNQYV
                     PSGSVLARILPDLTEQTVADIKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQSLYYGLAGQASVITGTKTYWDYFADKMFNH
                     R"
     CDS             complement(5001..7193)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 311.7; E-value:
                     1.6e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_8"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1107.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.8e-41, bitscore:
                     132.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQANMQLFDLEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQ
                     LQQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKL
                     QMARVANNRLNEVYLVESEFKEQRHLTERHLIEGPIRVRDVSFKYGFGQDVLKNVNLEV
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVP
                     QDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILS
                     GGQKQRLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIA
                     AKTEQIVVMDHGKIVEQGDHATLLAQDGYYARLVHE"
     CDS             7808..9103
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MTLMSDTTYFFITLPIFLTGIYFLTFVFESRSRVIHITFWSVFGT
                     LLSLLLSTYGEVFFFIIYACYVAKTTSRSNVFWVFIFMEVNLIVITAHTTSTQALVLLK
                     ARLDPCILIADSVINLAVFIATIWLLSKKKEQIIKLRDLVREQNKLQRSILIYTGANCA
                     SLYCFEATWNLIDLNNFLSWLSLGVFLLSVVISLYSIFFILKSYKYYIELIWIKRAESS
                     QRAYYATLAQQQKRTDKLLHDYKNLLATLQLSMDQSTHNISSETRDVVSKAQQALSQVE
                     FNQETFDAIKSDSLKSLLYLKWTEALHQNIKMYVHIEGIIEPLDSSTSFAVIRALGILI
                     DNALEETSRSGNSKFSVLLINSSSYLEVNVINDVTAGFELSNLNQSGFTTKGHGRGKGL
                     TIINELIEQNKKISLKKKVKDNQLKITLFVWR"
     CDS             9108..9884
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MSKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLATIDWSAINDSIFLLDIELGDSATSGVDVATAIRKKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLE
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVLRL
                     DITNRFVYMDNQDKLEVSIRRIGELRNILTGTRALS"
     CDS             complement(10291..10473)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MTVVIYSILLILAFFFTFVFVTAIGWQMIDLLRHRLHPRTSFWEK
                     YSQLTQLAISILPFS"
     CDS             complement(11492..11791)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MKKLKWFSGGNERAEQAIQLIDELLRDFDDSSSHSDRLRTVLRNN
                     REALIYKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             complement(11970..12128)
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLAIPVAAILGFLATDAWSHADELVAGV
                     KQGWERS"
     CDS             complement(12597..12782)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_14"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.7e-08,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEIVDKLNGN"
     CDS             complement(12842..13027)
                     /locus_tag="ctg2_15"
                     /transl_table=11
                     /translation="MTMRTGLALKEISGKMLELTSGGNVPLSNCSVDPPNERHPPAYES
                     AFKYKLPIVHPIKVAT"
     CDS             complement(13413..13598)
                     /locus_tag="ctg2_16"
                     /transl_table=11
                     /translation="MSTRLTKLVDYGLIIATIIFAIYTVTSAIGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKSA"
     CDS             complement(13648..14454)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_17"
                     /sec_met_domain="Abi (E-value: 1.4e-14, bitscore: 47.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYTLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQVIVLKVTLSRPRLKPVIIWGLLFILIAWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGGLIRAFYVAHHRHAKYQLLFCIGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEKFLARLSHS"
     CDS             complement(14775..15215)
                     /locus_tag="ctg2_18"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNAKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKISSTLKKSGILTSKTGLNGGLRLAKTPQTITVYEILTAIEGTAPLFKLHQEIDPAAF
                     VNGERVTSWLTASTNVLNRAEDAMVQVLKQTSIADLAEAAEA"
     CDS             complement(15270..16697)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 326.9; E-value:
                     2.7e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_19"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQIIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAAQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAARYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPIPTLLISAVLWVAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSKVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTSSLTKIADVFGQAMLIGVGMTIV
                     GLILVVTLIIPAEKAAK"
     CDS             complement(16870..17202)
                     /locus_tag="ctg2_20"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKQAASGGLMETEAQEVVDEALDILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
ORIGIN
        1 attcatccac cgcaacgcta tcattttcat taatgattgg catcacctgc cgcttcagca
       61 aagcatcgat ggtatccaaa acatgctgcc gagtttgcgg ataatcaaaa acgtcatgcg
      121 ttaacaacaa ctgaccaatt ttagcgccat aatcgctaaa cctttgcgta tacaacgtca
      181 ttaactctga ttgaccaatc gccgccaacg cctgctgctg agcaatttca gcaggccgca
      241 ccgtcacacc aagcttggcc atcccaaccc caatcgcacc agacgtgact aaaaccagct
      301 cataaccttg attcgtcaaa gccgccaacg tatacgccag ccgatctatg gtctgcaaat
      361 taaccttgcc attttgatga atcaaactac tcgtccctat tttgacaact aaccgtttac
      421 aatgcagcat ccgtttcacc atcgctacct ccacttaccg ccgattacca gaatattaaa
      481 aaagccccgc cttgatcgag acacccgtta aggcggtacc attctcgttc aaagccgtgc
      541 tttgcgcttt tttactattt aatttcgtca atcttcaatt caagcttgga ttcgcgggcc
      601 attcagaact ttcagcaaat gtcctgatct ctgtgagccg ctactatgac ttgatgaagt
      661 gattgtatgc ggggtgtcgg gaaaagtcaa gcgggttatt cggttctggt aacatctata
      721 cagggtgtat ttttaaacaa gtctgcccat tcatcagatg ttggcaatac gcggagaaca
      781 atggcatcat caacaacttt tacaaagagc tctctcgttt cgtcaaggtt tagttgtcta
      841 tgcattttaa ttggtatgac aagccgatgt ttaattactg actcttaact ttaagcagcg
      901 tgcttatgtt tacgctttgc tttgcgtgcg acgaacaacc attctccgag gaaggaaccg
      961 cagacaccgc caacgtagat ccaccactta aaaggaatgt tcgataactt ggcaagaata
     1021 aatcccacac tcattgctcc tgcaagggcg gttgcgaagt tacggtgttg tttcatgtcg
     1081 cttcaacttc tttcaatatt tagtctttgt tgaacccata atttgaatag atgtcattag
     1141 tctttctact ggttaaccaa atagctttcc aaagaagcta caatgatgcc tattccaagc
     1201 tgcctacgag gtgcttacct tgccacgtga ccgccaacaa cagttcttga acaattatcg
     1261 ttgcacgctt tctagcagcc gctacagcat catcgcgtcc ccagacttca agaccgtatc
     1321 aattgttaac ttaaaaaaga tacgcttctc gaacacggct ttgctcagtt tttatcaatc
     1381 gttttataaa atgctatcta aacctttgtt gatgcagatt atacatgact cgcattttgt
     1441 gtcaaaaaga atacacggaa tttttgccaa atacacatta tataacgatt gatatacaac
     1501 aaaattaaga acctgactca ttcgtcaaaa caaacagtaa gaaaagtaga acgcccgtaa
     1561 gaatgaagtg gggttatttg tgttgctaaa aagttatact gatcaatcgc tttgccgcca
     1621 gcgagaatcc ataatcaagc gagcggtaaa caagcccagc ggtaaaaaca taatgataag
     1681 tgcggcacgc gtcatccatt cggcaccgac gccaatatta ttcaatccaa tattgtaaac
     1741 tgcccggtaa atatacaagc caggcaccat gatgacgatt gatggcactg ttagcgaaat
     1801 ccgcggatag ccatcaacgc gattaatcgc cgacgcaatc agtccggcta ccaacgcgcc
     1861 gataaatgcc gccgcagcag ggggaatcgt attgagatcc accaattcaa gccgcaacgt
     1921 attcgccact gccccaatca acccggcctg gattgccatt cggcgggggc tgttaaacat
     1981 caccgagaat ccaaagaccc cacaaaagct ggcaatgagg cgataaacca aaagaaggat
     2041 cggactcagg cctaagtcga caaagttttc cgggcgtaaa tggacaacca ttgcgaccag
     2101 ccaaccaacc agcgaagcca caatggtaat catcaacgca tacagtagtc gttccattcc
     2161 cgagcgcata tcctgcttcg aaatatccag catactggtg ataaatggga agcccggaat
     2221 cacaaacaac atggcgccga tataccccgc ttcatgccgc gccgcaatgc ccagtcccat
     2281 ttccagtccg cgaaaagcga taaaataaac caagcaggca accgccacac tgacaccgat
     2341 acaagccagc agtgtccagt tacgccgaat catgatttca cgcagccaat taccgatccc
     2401 tgcaccaaca aaacaacaaa ccatttcgat aggaccgccg cctaacaaaa agacgaaagc
     2461 gcaacacgcc aaagcagctg ctaatccggc gcgcaacgga tcgtaattgc cagacatctt
     2521 ttgaatctga tcaagtcgat gatgaatatc ccgcacggtt tgagtcgcat actctttgtc
     2581 aaaatgacgc acaaaacgtt ccaacgcatc caacttgtca gtattcacac cgctttttgg
     2641 cagtgaaagc acctcagaat aggcatggtt attgctaaag caggtatacg ataaggaaat
     2701 taagccaata tctgctgagc acgacatccg caatgctcga gcaacggtgt tcatcgcctc
     2761 acgcacgcgc cacgccccgg taccacacgc cagcaacatg atcccgactc ggccaacgag
     2821 tgacgcgcgc tcttcaaggg tggcatgatc ggcttgccgc tcttcgctga caatcacgtc
     2881 ataccacgga atctgcatat gatgtttttc tgaaagcggc tggtctcccc gatccgcttg
     2941 gttatctttt gccttcataa ctcgtgctaa tccttcttct tatagggatt gtctttttca
     3001 aaaaaattga aaataaacat tcactattct agcacaattc ataacagggt gtatttttga
     3061 ctttttgaaa ctaatgaatt tgaacgcctt attcatgaca agcacgcaca aactagcaat
     3121 catttctcgg tctcaactta ttgcatatga tgttggaatc gctgcgccag aaaatgccgg
     3181 attcgcaaaa agcgacgagg atcttccttc ttctgtccat tagcaatcct tcgtagttcg
     3241 tcaattgcat ctcgtccttc ttgactcaac cgtacacttt cagtcgtgag gataaaatca
     3301 attcttagta tcatccgaaa aacatgccgt cgtaattcat agccatgaaa accatcgcgg
     3361 ataatctctt ccttggttct ttccacaact tcttcaatat tcgtttggcg gatgagctgc
     3421 ggttgttcat gtaattcatg caacaggcag tcgatatagc cttttgtttc taattcttcc
     3481 tcgtaatcca tacgccgatc accgcctttc atttgactaa cttgatccgc atcgtttttt
     3541 atggtcattt tcttaaataa tgggcatcgc cttttcgcta ctaaacaaca aaagcggtaa
     3601 ataccgattt atcgatggtt aaacatctta tctgcaaagt aatcccaata agtctttgtg
     3661 ccggtgataa cagatgcttg gccggctaat ccataataaa gggactgccg ctgcgattta
     3721 gataatttca cccgcgcctt gaccgtaaag aagttaccaa ctttcggatc gcgtgttggg
     3781 gcgacgtcaa tcgcataaac ccggccatct aatatggtag gggtcggcac attctcagca
     3841 attcgcaggc gtactttctg cccacgcttg atgctcatga tctctgtcgg cgaaacgcct
     3901 aattttatgt cagcaaccgt ttgttccgtt aaatccggca gaattcgtgc caacacgctt
     3961 cctgaaggga cgtattgatt cccggccaag gcagtttcta aatgcaaaac gccactggca
     4021 cttgctttga catgatagtt ttgagtttca tcattcaagg tagctaactt agcctcgtct
     4081 gcttggacct gttgctgaac cttcgtctgt tccgcaacgg ctgtttgctg caaccgactt
     4141 tgtaatgcgg ttagattagc ctgagtctct cccgcttttt gagccgatac atctgcttgt
     4201 ttttgaccgg cccgttgctg ctctaaagac gtcaaattgg tttgttcctc atccaactgt
     4261 gtctgtaatt gagcaaggta ctggcgttta aggttcgcct gtgcctccgc gtcggtattt
     4321 tttatctcac tttcatattg ttgataaagg tagtgatagg cgtggcgact gggcaagggt
     4381 ttgttcgcct gaatcgccgc ttttgcctcg gagatagcgg ccatttttgc ttggctcgtt
     4441 tggatactgg cgcttagtaa ccgatcaatc tctttgtttt tttcactagc gacggtttgg
     4501 gttgcctgct cagcctctgc tgtcagtgtc agcactcgcc gttgactcag ataatcttgc
     4561 acctgttgtt gatagccgaa tcggtctgcc tttgaaaaaa gatctttgtt ttcggtaaca
     4621 ctttgtttca aaacatccaa ttgctgctgt tgctctttta gcgttgccag ttgctgcttg
     4681 agtaatttaa tttgtgttgg attggcgaca tcgtggtaaa caagtaaggt ctcgcctttc
     4741 ttcacgcgct tgccttcttt catgcggttc gagacgatcc gattggcggc cgtcgcctga
     4801 actgtcacgg ctgcctttac cggttcaatt tcggcagctg tcagcacagt tacctcgcgc
     4861 cgagcaaaga tcagaaacaa tagcaagcct aagaaaagaa tcgtactagg cataataatc
     4921 atcgttgaaa aattgcgaaa gcggtgctgg taatattcgg tcgttgcaag ttttttggga
     4981 tccatcatct aaagctcacc tcactcatga accaggcgcg cgtaataacc gtcttgggct
     5041 aacaacgttg catggtcacc ttgttccaca attttgccat gatccatcac cacaatttgt
     5101 tcggttttag ccgcaatagt taagcgatgg gcaacaaaaa taatggtccg atccgtcatt
     5161 gccagcaagc gatcgacaat ttttcgctct gtaatggtat ccagactgct ggtcgattcg
     5221 tcaaaaatca gtacttttgc cggtgacaac aaggcccgtg caatcgccag ccgctgcttc
     5281 tgaccgcctg ataaaatact gccgctttct gacaatttgg tctgccactg ctgcggtaag
     5341 tttgcgatgt ctgcggcaat ttccgcagcc aaacacgcct gcgtcaaatc ttgttccgaa
     5401 acatccgaac ggctacctaa cgtcaaattc tccaacaccg tgcccgaaaa aataaacgga
     5461 tcctgaggta catattcaat atattgccgt aatgttgtca ggttaatgtc tttgaccgga
     5521 atgccattaa acgtgatggt tcctttatcg gcatcaaccg ggtaaaagcc aactaataat
     5581 tttgctaatg tcgacttacc agaaccgctc atgccaacaa tggtatattt agcattttcc
     5641 ggcacttcaa ggttgacgtt tttcaataca tcttggccaa aaccatattt aaacgagaca
     5701 tcccgaacgc gtatcggacc ttcgattaaa tgccgctccg tcaagtgccg ctgttctttg
     5761 aattccgatt cgaccagata aacttcattc aggcgattgt tagcaacccg cgccatttgt
     5821 aactttggct gtaggttgat gatgctttca agcggattcg taaagtatga cagcagtgca
     5881 ttaaaggtca gcatctgccc caagctcatc cgattggcaa tcaccaaact tgccccaatc
     5941 cacaacacca caacgttcaa cgccagcttc aacagacctt taatcgcttg ctgtaattga
     6001 tctgccttgg tgtaactaaa cgatttcttc agataggtta gaaattcccg atcaacccgt
     6061 tcatagctaa ctcgttcgcc ggtcagggac ttgatggttt caatgccatt caaatcttca
     6121 ataatcgatg aactcaagat tgcgttactt tccatcgtct cttggttcaa ccgatcaaac
     6181 ggccgctgaa atgcaaaaac aatcaccaaa taacacggca cggcaatcaa tgacactaaa
     6241 aacaaagtcc cattttggat ccctagaaca atgcctaata ttaggacaat ccagacatcc
     6301 aaaaacaacg tcataatcgt attcgccagc gcgtcaataa ttttattggc atccgcaaac
     6361 cgcgacacaa tctctccggt ccgccgagtt gaaaaaaacg acatcggcaa ttcatataag
     6421 tggcgcacat accctaaaat gacatcaatc gcaagccgct gccccaacac cgccatcaaa
     6481 aaattctggc cataagtcaa cacagcttgc agcaagtaag ccaccaaaag gccactagca
     6541 atcatcccca tcgtcgtccg catggcattc ggtatatacg tatcaataat agactgcaaa
     6601 aaatacgacc caacgatact aatgaccgta atcaataccg cggccagaat aatgttcgcg
     6661 ataatacctt tttgcttagc cagcatgggt acaaacgcaa acaaactgcc tttgtcctcc
     6721 ttacgcggct gatactgcgg cgccggtgca ataaagatgg ccacacccga ccattctttt
     6781 tcaaacacct ctcgcgaaag ccaggtcatg cgcactgacg ggtcaggatc gccaatcaga
     6841 atactcgtgc gcgttgcttt aaaaacaaca tagtaatgaa gcaattcacc gcgcttcagc
     6901 acatgggcaa taaacggata aggcacatcc tcaagatcaa acaactgcat attcgcctgc
     6961 accggtttcg tctcaaacgc tagtgcttca gcggcccgaa cgattcccaa agccgtcgtg
     7021 ccatcctgat ttgtcttcgc taactcgcgc aagtgggcta acgaatagtc cgacccattg
     7081 tatttaagca gcatgtttaa cgcagccaca ccacagtcac gctcgtcaac ttgtgcggtg
     7141 tagaaacgtt tgtagtaggt gatctggcct agttttgggg tgtatttaac cattaactct
     7201 cctcgcttat taagccatta gattcaggcc tcttttatga gccgatatac catgacgttt
     7261 agtcaaaaat acaggtagtg aatccccaaa tttggggtta cccttttgat ataagcactg
     7321 taagatttag ttttttacat ttaaaatgtg tggtagtata ttttagagca ggattaatag
     7381 cgtataaaaa taaatattaa aattaaaagc acttttatat atctaaatat ttatttttat
     7441 acgttgaagg caatcgtctg tctggccttt aatgcttccc ctgaaactgt tctatgagcc
     7501 actttctcaa attattaaat gttgagctta ttggtcggcc accaccaagt atctccgtaa
     7561 gacgatcatc cgaaattacg ctgcttttca tctgacgctg aaactccttt ttgttgttca
     7621 tttcaaccta cctcctacga tttattcttc tgtatttaac ctaacatgtc gtgagctttt
     7681 tagggcctac aaaaaataaa cgtcgtgttt tggccattta acgttatatc gttagcatat
     7741 gacgtcattt attttcattc ggtatgaaga acttgccata ctttcataac tagcggaggt
     7801 tttctatatg acactgatgt cagacacaac ctacttcttt ataacccttc ctattttttt
     7861 gactggaatt tactttctta ccttcgtttt cgaaagccgt tccagagtta tccacattac
     7921 tttttggtca gtcttcggaa cgcttctgtc tttgctcctt tcgacttatg gcgaagtctt
     7981 cttttttatc atctatgcat gttatgtagc taagaccact tcacgttcaa atgttttctg
     8041 ggtttttatc tttatggaag tcaatctgat cgtcatcaca gctcacacta ctagtacaca
     8101 ggctttggtc ttgctcaaag cacgccttga tccttgcatt ttaatcgccg actcagttat
     8161 taacttagca gtattcatcg cgactatctg gttactatct aagaagaaag aacaaattat
     8221 aaagttgcgc gacttagttc gagaacagaa taaattgcaa cgttccattc ttatttacac
     8281 aggcgcaaac tgtgcgtcac tctattgttt tgaagctact tggaatctga ttgacctcaa
     8341 taatttcttg tcctggttaa gccttggcgt attcctactt tcagttgtga tcagccttta
     8401 ttcaattttc tttatcttaa aatcctataa atattatata gagctcatct ggattaaacg
     8461 ggcagaaagt tcccagcgtg cttactatgc aacgttagca cagcaacaaa agagaacgga
     8521 caagctcctt catgattaca aaaacttatt agccacgttg cagttgtcaa tggatcaatc
     8581 aactcacaac atttcttctg agacgcgaga cgttgtttca aaggcacaac aagcgctatc
     8641 tcaagtcgag ttcaatcaag aaaccttcga tgcaattaaa agcgattcgt tgaaaagtct
     8701 actctattta aaatggacag aagcgctaca tcagaatatc aagatgtacg ttcacatcga
     8761 agggatcatt gaaccgctcg atagcagcac ttcattcgcg gtcattcgtg cactcggtat
     8821 tttaattgac aacgctttag aagaaacaag ccgctccgga aactcaaagt ttagtgtctt
     8881 attaatcaat tcaagctcgt acctggaagt taatgtcatc aatgacgtga ccgcgggatt
     8941 tgaactatca aatcttaacc agtctggatt taccaccaaa ggccatggtc gcggaaaggg
     9001 gttgaccatt attaacgagc tgattgaaca aaacaaaaaa atcagcctta agaaaaaggt
     9061 caaagataac cagttgaaaa tcacactttt tgtatggagg taactttatg tctaaaaaca
     9121 aaacgatcct aaacatttat attctcgaag acaaccctga ctatctaacc tttatccaag
     9181 aaactgtgca gcagtacctt ctgattgaag aactacccgc caagatccgg ctggcaacaa
     9241 cgtcagcaac cgaactgctc gcaactattg attggtcagc catcaacgat agtatcttcc
     9301 tccttgatat cgagctggga gattcagcga caagcggcgt agatgtagcc acagccattc
     9361 ggaaaaagtc atattatgtc gatatcctct tcatcactag ccatgtagat gaagctttaa
     9421 ggattttaga gcacaaaatc gcacctctgg acatgatcaa caagaactca ccttcaaaga
     9481 cagaaaagaa aattcgaaat aacattcttt atgcaataaa acgtctaaag gcgcgtcagg
     9541 tcgcatctcc cagattattt agctacagca tcaactccag tattttttca cttgaaatgg
     9601 atgagctcat ctatattcaa actgctcccg gcgtctcagg gacactggag cttcatgcag
     9661 aaaatgaaat cacaaccttt cccggcaacc ttaaggaact agcgaccaaa tataccaact
     9721 tatgtcgatg ccataagagt atcctgatta atcccgcaca tgttttgcgt ctggacatca
     9781 caaaccgatt cgtttatatg gacaatcaag ataaacttga ggtcagtatt cggagaatag
     9841 gcgagttgcg caacatctta acaggcacac gggctttatc ttaagaagag tgtgactggg
     9901 caatcatcct agatttctgt taatcaacac agctgaacgc acaaataacg catcctcaat
     9961 atcaagggtg cgttatttgg ttggtttata caggttggaa atactattcc tcctgaaagg
    10021 ttttatgcca atctgtcatc ggttctactt caaccaaagc gctatcgact gacccgtttg
    10081 ataaccagcg tcataaatcc cctttaaaat tcccggtgaa aagtaccaaa acgccattat
    10141 taaaacccca atggcaacaa gcaacgacac tttctgttgg aatgataatc ttgcaaattg
    10201 atcgattacg ctcacctcgt ttacgagcag acttattttt acttctttca gtaatccatt
    10261 agtaacctgt tctttatgtt ctcccgcctt ctaagaaaaa ggcaatatac taatggccaa
    10321 ctgcgtcaat tgggaatatt tctcccaaaa agatgttcgc ggatgaagcc gatgtcttaa
    10381 gaggtctatc atctgccagc cgatcgcagt tacaaatacg aatgtgaaga aaaatgccag
    10441 aatcaaaagt atagaatata tcacaactgt cataagcaaa gctccttgag tcttccttta
    10501 aatttacatt gaagcggcaa attagcgagc acaggttcgg agatactata cgttctgcta
    10561 aggtcatcat acaagtaaga agtcacaaaa atgaagccat tttacctatt taatattgtt
    10621 tccgaaaggc cttttactgt caggaagaaa aaacaatcgt gggttttgaa agctcatctt
    10681 atttagcatc agttctgcca tactcacgcg caagatctcc tgatttgtat ttttgtttca
    10741 atacaaatca ggagactttt gcgttttttg gctgatcgaa catagtgtaa caagattctg
    10801 acactaaaaa cagttcccaa atatcagtag tgtcacctaa aatctcattt gccgtcatga
    10861 acagccgata ttgcattatt atagcctggc agatggctgt gtcacaatag ttgctgtctc
    10921 cttgagatga caggcttccc actgacaata acactgccac cttaccaata ctttgaaatc
    10981 aaacaaagaa aatttgttat ttagagcgtt tacggtcttt aacctttgaa gatgtgacac
    11041 ttaatttaga gaaaagaatc aaaacaatga agattgaaag catctctatg aacgcccgga
    11101 cgatgaaaaa atcaaaaccc aagcaatcga caatcagctt gtttaagaca tcactgagcg
    11161 aaaacccgcc gaaacagata caaacgataa tccagaaaga agcttcatta agctatgtgc
    11221 gcatagtttt aagaatcgtc atcgtacctt cgctttgctc atcactaaat catttatcga
    11281 ccgatcagtt ttggctctgt ctttttaagt tagaccgtta tattcgaaac tagtttgcct
    11341 acgtcgccgt tataaaatgg acaacctttt aggcatcatc cattgacaac aggcccatac
    11401 caaccagcat cgcaatcgga gtttgatctg caccaaatga atcagtgagc ctaaccataa
    11461 tcaagcgcac tcaccgtttt aggagtggcc tctagtaccc atatctgata ttcgccagcg
    11521 aagaaagctg ctcgaatttg tcagattgtt gcttggttaa caagatattg ttttgcaaca
    11581 gggcattaga gatttctaga ttcatgcggc ttaaaataaa tggaaccgct gcttgcttgt
    11641 aaattaaggc ctctctattg ttccttagca ctgtccgtaa gcgatcacta tgggaagaac
    11701 tgtcatcgaa gtcgcgaagc agttcatcga taagctgtat cgcttgttca gcccgttcat
    11761 tcccaccaga aaaccatttc aatttcttca tctttcactc caaaaaagtt gcgctagtgc
    11821 accttcactt gtaacacgtt tggcgccgtg cattgccaga tctgccgtag caatgacaga
    11881 aagaacatgc tcgcccacag ataaaaggct tgttctgggc agagatactt ttacaacggc
    11941 gacaacgctt aagaattaac gcaccgttat tacgatcgtt cccatccttg cttgactccc
    12001 gccaccagct catcagcatg gctccacgca tctgttgcca ggaatccaag aatagcagcg
    12061 acagggattg cgagcggtcc gataccgccg gaaatcttac tcaattcagc ttcattcaac
    12121 ttagtcatta aaattacctc cttgtatttg taagaaacta ctcgccagtt gatccaaaag
    12181 tctttgttat ggatattgtg gcgataaaat gctcatctac cgcacaactt tttgcaaata
    12241 caaccatgga gtcatcagcg gcatgcctgg attaaagtca cttgaccttc accatcgaaa
    12301 ttctgctact tggtttgtac ggcagcatta cagcgtacag cttaggcatt gaacggaaca
    12361 ctcaaagttt aagcgtaggt aataaaccag atggcattca aaatataagc acgtttaaag
    12421 gctatctgat gctcactgtc gagatattta tcattccaaa cgcgatagtg accatctttt
    12481 ttacagcacg tatataccaa aacacctaat agatatacca agataaacgt agctaacatt
    12541 aaaagattta tcttattcat acgtttgccc gttcgagtgc ctattcatcc cggatactaa
    12601 ttgccgttaa gtttgtcaac aatctctttg gcaggaccaa tggctggcgc aaacatggcg
    12661 ccttcagccc aagaacgcgc ggttgaacca atggccttcc cgataaaggt ccacagatta
    12721 ccattatcgc caccagaaat acttgccaaa tcagccgtgt ttaaagtttt taaatgatcc
    12781 atgttcttcc tcctttttcc tttatgagcc tttcaatcta tctatcagcc taaattatca
    12841 cttaagtcgc caccttaatt ggatgaacaa tcggcagttt atacttaaat gccgattcgt
    12901 aagctggcgg atggcgttcg tttggtggat ccacactgca attggataaa ggaacattcc
    12961 caccgctcgt caattcaagc atttttcccg agatttcctt caaagctagt cctgttcgca
    13021 tggtcatccc attttcctcc tttccctttg ttagaaggac ttcccttctt ccccatcaat
    13081 ataaagtaga cagccaggtt tgtgggaatg aattttttaa cgtcgatttt tgcaagaaaa
    13141 tcgtcgtaaa aaacctaatt ttgacgttta tcgttaaaaa cccggcgatt atttgatatt
    13201 gccgccttct cttcaaaact caagcaactg caactgtatt tacttttacc catgtctttt
    13261 tcgccactgt gagcatccag tcttaagcca acttagaaag gcgattaggc tcgcggccag
    13321 catgtgcatc cattcgccgg ggaaatgatg acaaactgca cacatataac cgacaataaa
    13381 tgttaataag cagcgccaaa atcttttttg attcacgcgc tcttctgctt ttcctcccgc
    13441 tcgcttaaca gcattaacaa cgtcatcaaa atcaacattg gcgtcacaaa actcccatga
    13501 ttggtccacc caattgccga tgtgaccgta taaatggcaa aaataatggt agcgattatc
    13561 aacccataat cgactagttt agtcagtcgc gtagacatcg tttttctcct taaactcgtt
    13621 ctatcataat tgatacatac agccagttta cgaatgcgac aatcgtgcca gaaacttttc
    13681 attgttttgg ccacggcgaa aaagtcgcag tgcaatcgcc aggtaaatcc cggcaataag
    13741 gaatgcgtga acaatcgtca tcgttatagc gttgggatca ctaggcgctt ctttcggata
    13801 cggtccacta accaaagtga taacaaaatc aatcaaaaag tggatcaata ttggcataag
    13861 caacgatccg taacgaatat aaagtgctgc aaaaatagcc cccatgccaa atgcctggat
    13921 cacttgggca attgttatca caagcccttg agcaggcaaa ttactcaggt gagccaatga
    13981 aaaaacaaga ctgcttaacc ctatgcaaaa taagagttgg tatttggcat ggcgatgatg
    14041 ggcaacataa aacgcccgaa tcaacccgcc aagcatgacg ccacgaaaca aatactcttc
    14101 gggaacagcg gcaatagtac caatcacagc tgcttgcaag acgtcaatcg gtgttcgatt
    14161 tgtaaccgtg aaccaagcga taagtataaa gagcagtccc caaatgataa ctggcttcaa
    14221 tcgtggtcga ctaagtgtca cttttaagac gataacttgt ttcagtaaca gccaattaag
    14281 tgcgatcatc accagtaaaa tgatggcttt aaataagata ttcccagccc agaagtccaa
    14341 tttcagcgtg taaactgctg gaattaaaag cagctggctg attagcacaa ccaaaagcaa
    14401 gatatataaa acgcaaaatc ctggcgacaa tagcaaatga cgttttcttt ccatttatcc
    14461 accttcactc gcacgtttca atgcaacgca gcttcgatat cgctacccac aatataccga
    14521 ggctgcgcat gttacggatc attaactttt aaacgtcggg ttttcgccga taatcgttgt
    14581 attttgaaac ttgacaacgc gttaatcgtc cccatttccg aaaaggtttg ccaatggagg
    14641 cgcacttgct gactatttac tgactgcccc acagttgcac gatcctgaaa atgccgtaag
    14701 caaaatcgcc tcatccaata ccaacgcgcc aacgttagtc ttgaatgagg cgatgaaaag
    14761 ttagatttcg atttttacgc ttctgcggct tcagccaaat cagcaatgct cgtctgcttt
    14821 agcacttgca ccatagcatc ttcggctcgg tttagaacgt tggtgcttgc tgttaaccaa
    14881 ctcgtgacgc gctcgccgtt gacaaacgcg gccggatcga tttcctgatg aagcttaaat
    14941 aacggcgccg tcccttcaat tgccgttaag atctcataaa ctgtaatcgt ttgtggcgtt
    15001 ttggctaatc gcaaaccgcc attgagaccg gttttcgacg ttaaaatacc acttttttta
    15061 agtgtggacg aaattttttt aatgctagga accggaatgt ttagcatttc ggaaatcttt
    15121 tgaatcgata aatagtcttc atgttgtgct tgggactttg cgttgacgta ggccgtgatt
    15181 tcaagtgctt gcgaaaatgc gactgaaaaa gccatcgaat atacctccca ttaaacgatt
    15241 gtgtatattc tattatacca atgataccgt tacttggcgg ctttttctgc cggaataatg
    15301 agcgtgacga caagtatcag gccaacaatg gtcatgccga cgccaatcaa cattgcctgt
    15361 ccgaatacat ccgcaatctt agttaagctg ctagttgacg ccgcaaagat tgccagtcct
    15421 aaagcgccgc caaattgtcg ggcggtgttg tagacgcctg atgcagctcc cgaaatttcc
    15481 ggccgaattc tagccaaacc tgaagtagcg agtgtggcaa atgccagcgc gaatcctacc
    15541 gcaaatccga gtgtcccaag taacaaaaac cagtaattgg caaaccgtga tgccactgcc
    15601 agttcagcca atgaaagtag caccgtgaca aatccgaaga tcatgacctt tgaattacgc
    15661 caccgatcaa cgaaggtccg ggccttgact gccacaatga agagtaagat ggccattggc
    15721 accatgccta atgcagtcat aaatggcgtt aatcctaaga cgccttgcat aaactgaggt
    15781 gtgtagaacc aaaagccgat tgcagcggca ctaaacaaca gagaactgac ataagaagcc
    15841 atccgttccc tatccgtaaa gatttccagt ggcattgtcg ggtgggcaac gcgaccttga
    15901 ctagcaatga atgcaaccca aagaactgct gaaatcagca acgtggggat tggccatgga
    15961 ctgccatcta acccatatga gattgaagtc atcgctaata ctgacaagat cgtaccaatc
    16021 cagtcaatct ttccggtttg gcgttttgca ctaggtaaat atcttgccgc aataccaacc
    16081 atgattaatg cgatcggacc attcatgtag aaaccgaccc gccatgacgc aaacgttgca
    16141 aagaagccgc caatgactaa accaaccgct gcaccggctc caatgacgga agcatagtag
    16201 ccgattgccc gctgtcgtgc ttttccttga aaggtgtctg ttaacaaagc caaacagttc
    16261 ggtgcaagaa tggccgcgcc cacgccttga acagcgcgaa agctaatcat gacaagcgca
    16321 ttggtagctg ccccgactgc cagactgcca actccgaaaa tagctaaact cgcaatgaat
    16381 aatggtttgc gtccgtaaat atcgcctaat ttaccgccta ctagcatcag cccagcataa
    16441 gttagcgcat aggccacctg cacccaagac aacgcgccag cattcaaatg caattgtgcc
    16501 gccattttaa cggtacccgt gtaaacaatc gatgtgtcaa gcacacctag aaaagcccca
    16561 atcagtgcca gccctaaaat aatgatttga gtcgctgaca tgcgctgcga ttgggtgatt
    16621 gccgcatctg tttcctcaat gacggtgtcg tcagccaggc catcattgat taattccttg
    16681 tcttcttctt tgctcatatg agatgcccct ttctatggtt cacttagtat attccgttta
    16741 tactaatatg gcaaatcttt tttaagcaaa aaaaccacgt gttccttaat tctatggaaa
    16801 cacgcggcta caagcgaatt cttttcgggc cggttactgg aatcagacca tggcttgggc
    16861 aacaactgtc taaataataa agtgcggccc gcctacctga ctcaattcgc catgaatgtc
    16921 attttccata aagtctttta ccgcctgcca ccactgattg gcctccgctg aaagtttcat
    16981 tccttgcaag ccgattaatc gcgtaaaccg tgcgtatagt cgcgacaagg cgtaatctgc
    17041 ggctcgattc ttgagcacat taggccgctt taaaatatct aaggcctcat ctacaacttc
    17101 ctgtgcttct gtctccatca ggccaccact agccgcttgt ttcagactca ggtttaatcc
    17161 ggtcaaaata aacagaatct gatttcgttg caccatattc atgagtgatc ctccatgtct
    17221 ggtcgataag tgtttgcatt aagatagcgt tttcttgaat tgctaactgc aatataccaa
    17281 atttatcaag cttcaggtca aactttcgat aaacgtagcc ttttcgccga ttaacgttat
    17341 tgcggacatg aatcgcccgg tccaaagcgc atagaaaaag ccgtggcgca ttaaccacga
    17401 ctaatcggaa gcgcgtattt cagcatagtc gtaaaaaggc cgaaatgaca cagttcatca
    17461 gcatcgaaca agctcatatc ccatgcggct aattaatgcc cgccacccca gacaatcgga
    17521 atagcaatca gcccagcagc cagcgcctga tcgcgataac gcttggcatt gacttgatct
    17581 gctggcacat ccgccttgat cgcattgaaa acggcgatca tctcggctgg aatcgtgtaa
    17641 tgaatgagat aatacttgga aatatcatgc gatagctggg tcacgactgc gacataagct
    17701 gttttgtcct ctgcatcttc cagttgtttc gcgttggatt cgattatttg ctttaatttg
    17761 gcatcagctt tcacggccgg ac
//
