LOCUS       c00466_JAIZVS0..        5292 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAIZVS010000004.1 Lacticaseibacillus paracasei strain CJNU 1877
            NODE_9_length_25895_cov_10.382313, whole genome shotgun sequence.
ACCESSION   JAIZVS010000004
VERSION     JAIZVS010000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 23:05:07
            Original ID  :: JAIZVS010000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5292
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5292
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[58:292](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(59..292)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..5292
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5292
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(59..292)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg466_1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3e-15, bitscore:
                     47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(564..1517)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.7; E-value: 5.1e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg466_2"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             1722..2456
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 3.6e-12. Score:
                     38.3. Matches aSDomain: nrpspksdomains_ctg466_3_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.9; E-value: 1.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg466_3"
                     /sec_met_domain="adh_short (E-value: 6.3e-35, bitscore:
                     111.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        1740..2228
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg466_3_PKS_KR.1"
                     /evalue="3.60E-12"
                     /label="ctg466_3_PKS_KR.1"
                     /locus_tag="ctg466_3"
                     /protein_end="169"
                     /protein_start="6"
                     /score="38.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     aSModule        1740..2228
                     /domains="nrpspksdomains_ctg466_3_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg466_3"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1743..1823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg466_3_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg466_3"
                     /protein_end="34"
                     /protein_start="7"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             2482..3645
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     291.4; E-value: 1.5e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg466_4"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDTLKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGIKTPADAEKAAESFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSVTSSNVPQD"
     CDS             complement(3907..5169)
                     /locus_tag="ctg466_5"
                     /transl_table=11
                     /translation="MPMPVIRALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALP
                     DEKLQKDFPLHVYQTGSGTQTNMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFP
                     TVMNITAAIAVNQLLHAVNQLCSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWV
                     AMMEHDQIALKQLQPNLFYLAIGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNK
                     FAALAAHSEISVVHGAIKTLAADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPG
                     KVNPTQAEALTMAAVRVMGNDTTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTS
                     FTEKLAAGLTIHAPHMRALVDHSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAVK
                     SGDVTAAQFDKWVDPLKMTKA"
ORIGIN
        1 ggtggtaact ttaattatgc aatctagggt tttaaagtaa tgcccacttc tttacttatc
       61 attgcatccc atctcctaag catttaatag ctgacccaac cgctcctaag tttccaccaa
      121 ctacggcgcc gccgattatc ccaaaaggac caccagctag gccagtaatc gttcctgatc
      181 caataccagc cgtgatgcca gtaacaaatg tagcagcaca atcaaatttc tttttcccac
      241 ctgaaacccc tgacaactga aaatcgtcga gctggcgata attataagac ataattttcc
      301 ttttttcttc aaaaagcaac aagttatttt gtgtaaggtc gactttactg tctttaacat
      361 acattaatta tttgtgtaaa atgccaaaat tttttaaacg taggaaattt ccagtttaac
      421 gtcgtcttta cacttttatt gttcagttgc gctttaaaag tcaaaaattc ttaacgttta
      481 aatctccttg cttggtaaaa acttcaattt tttgcaaaaa aaatcgtctc agcaatttga
      541 gacaattttt tcatatcatc aacttacggc aaatcattcc ccgccgcaaa gtaaatgtca
      601 taccattctt gtcgggtcaa cgtgatgtcc gcgccttccg cactttcctt gatatgttca
      661 ggattcatag agccgagaat cacctgcaca ccaactggat ggcgtaatag ccaagcgact
      721 gcgattgcat ttttattggt gtggtagtgg tcagcgactt tctgcagttc atcattcaac
      781 gccttaaact tcgggctatc gataaaggtg ccttcaaaca tgccgtattg gaatggtgac
      841 catgcttgta aggtcatgtg tttgcgttgc aagtatggta ataggctgcc atcatgatcg
      901 accgaggcag cgtcggccat gttggtgtgc atccccgcat tgaccatgcc agtatgggca
      961 acggagaatt gaacttggtc aatcagcaaa ggctgccgaa tgccgctttc aagcaacgca
     1021 atttgttcag ggttaaagtt ggagacgcca aaatgccgaa ccttgccact ttgttccaat
     1081 gcatcaaagg ccgccgcaac gtcatcgact tccattaacg gatctggccg atgcaacaag
     1141 accgaatcaa ggtaatcaac ctgcaaccgt ttcaaaatgt gatcaaccgc tgacagtaag
     1201 tgatcttttg aaaagtcgta ccgtttgccg aataccaaac tgccatgaga gcgttttgga
     1261 tcaacgacga tcccgacttt cgattgaatg aataactgat cgcgggaaac gctggcttgc
     1321 ttcaaggctt caccaaaaac ctcttcggat ttgccttggc cataaatgtc ggccgagtcg
     1381 ataaagttga tgccgtcatt gtacgcacta tccagcacat tggccgcttt gtcgggggcc
     1441 agcacattca tccgcatgat gcccaaggcc acacttgacg cctgccaatt ggatccgcct
     1501 aatcgaactt gtttcataaa cacaaaactc ccttcgatac gtcatttcaa attatgttac
     1561 tgacgacaag ttaagtgtag cccctaaagt ccacttgagg tcaagccaat attagaattt
     1621 caataaaaca gcttgcatgg tgctgagctg cgcggtaggt taagttgtgt ctgttactta
     1681 ttttttctta gcaggataag cccataaagg aggccgtgat tttgacagtt aaagataaag
     1741 tggttgtaat cacaggtgca tcgagcggga ttggcgcggc aacggtacaa gtgttggccg
     1801 aggctggtgc aaaactagtc atcggtgcgc ggcgcacaga acggttggct gaattggcgg
     1861 ccagctttac ggacggtcag gtgctgtatc aacaaaccga tgtgaccgac cagcagcaag
     1921 tgaaagcgct gattgatttg gcgttggata agtttggtca tgtggatgtt ttgtataaca
     1981 acgctggcct gatgccactt tctgaaatgg ccgaactcaa agtcaacgaa tgggaacgga
     2041 tgattgacgt caacattaaa ggcgtcttgt atgggatcgc cgcggtttta ccgcctatga
     2101 ttgcccaaca cagtggccaa attatcacaa cagactcagt tgccggtcac attgttcacc
     2161 ctggaaccgc cgtttactcc ggtaccaagt gggctattca ggcgatcatg gacggcctgc
     2221 gacaagaaca agcggctaat catattaaaa cgaccatgat ctcgcccggt gccgtgaata
     2281 ctgagctttt cagcacaatt accgatccta agcgccgtga agctgttgaa gccgatgaaa
     2341 aaaacaatgg cctcagcgcc tcggatgttg ccaaggcagt tttgtatgcc attgatcaac
     2401 cggccaatgt tgccatcaat gaagtgctct tacggccagt cacgcaagaa cgttaatttt
     2461 cgtctaaagg agtgtgattg catgtcgggt tatcattttt taaaaccgtt caccttcaag
     2521 caccaaacca tcacgttgaa aaatcgcatt gtcattccgc cgatgacaac gcgcctgtcg
     2581 tttgaagacg gcactgtgac gcgggacgaa atcaggtatt accagcaacg ggccggtggc
     2641 gtcggcatgt ttattaccgg taccgccaat gtcaatgcgc ttggcaaagg attcgaaggt
     2701 gagctaagtg tcgctgatga tcgattcatc cccggtttga gcaaactcgc cgctgcgatg
     2761 aaaacaggcg gcaccaaggc tattttgcaa atcttcagcg ctggccgcat gagcaatagc
     2821 aagattctgc gcggtgagca gccagtcagt gccagtgcgg ttgctgcgcc acgggcgggt
     2881 tacgaaacac cgcgcgcatt gacatcggca gaaatcgagg ccactattca cgattttggt
     2941 caggctgtgc gccgcgccat ccttgctggt tttgatggca tcgaactgca tggtgccaac
     3001 acctatctga tacagcaatt ctattcgcca aactctaatc gccgaaccga tgaatggggc
     3061 ggtgaccgcg ataagcggat gcgttttccg ttggcagtcg ttcatgaagc agaaaaagtg
     3121 attgccacaa ttgctgaccg gccatttttg ttaggctacc gcatttcgcc ggaagagttg
     3181 gaacagcctg gcattacctt ggatgatacc ttggccttaa tcgacacttt gaaacaaacc
     3241 aagattgatt acttgcacgt ctcccaaagt gacgtttggc gaacctcatt gcgcaacccc
     3301 gaggacacag ccatcatgaa tgaacaaatt cgtgaccatg tcgccggtgc ttttccagtg
     3361 attgtggtcg gtggcattaa aacccccgcc gatgctgaga aagcggcaga atcctttgat
     3421 ttggtcgcga ttggtcacga aatgattcgc gagccgcact gggttcagaa ggtcttagac
     3481 catgacgaaa aggcgatccg ttaccagatc gcccctgctg atcttgaaga acttggcatt
     3541 gcgccgacct tcctcgattt tatcgaaagt atttccggtg gggcaaaagg tgtcccgtta
     3601 acaactgcgc agtctgtgac atcaagcaac gtgcctcaag attaatctag catttcaaat
     3661 catcgtgcga gtcgagctgt aaaaagctcg gcttttttct tgccgtcttc aacttacgcg
     3721 atggtgcctg aaactaccag tgatttataa gttttaaatc aaggtgtgat catcacctgc
     3781 tcacgctctg acttaaacgc gttcaccagc gcagctcggc tatgcgaaga acagtgacac
     3841 agatggtcca aagcccagac catctgtgtc actgccactt cgctacgccg agctaaccgc
     3901 gccagctcac gcttttgtca tttttaacgg gtcaacccat ttatcaaact gcgctgctgt
     3961 gacgtcgccg cttttgacgg cggctgcttt taaatcgagg ttttcttgct cagccaattg
     4021 cgcgatggcg gcactttttt cgtagccgat gtggggtgcg agggcggtga ccagcatgag
     4081 cgaatgatca acgagtgctc tcatatgcgg tgcgtggatg gtcaagccgg cagctaattt
     4141 ttcagtgaaa ctcgtgactg ttttggttag tagatcagct gactctaaaa aggtactgat
     4201 gataaccggc ttgtagacgt tcaattcaaa attgccttgt gacgcggcca ccgtgatcgt
     4261 cgtatcgttg cccatgactc gaacagcggc catggttagc gcttcggcct gtgtgggatt
     4321 cactttacct ggcatgatgg aactaccagg ctcattggcc ggaatgcgca actcgccgta
     4381 tccagcacgt ggaccactgg caaggaagcg aatgtcattg gcgattttaa gcagatcagc
     4441 cgctagcgtt ttaatggcac catgaacaac gctaatttct gagtgagccg ctaaagcagc
     4501 aaacttattg gttttcgccg aaagtggtaa ttgataaaca tcgctcaatc ggcccgccac
     4561 aatcttgcca aaattagggt cagcgttaag ccccgttccg actgctgttc cgccaatggc
     4621 taagtaaaaa agattgggct gaagctgctt taaagcaatc tgatcatgct ccatcatggc
     4681 cacccatccg ctgatttctt ggccaaacgt tagcggcgtt gcatcctgta aatgagttcg
     4741 accgatttta acaacacgag cgtaagtgac ggcttttgaa tataaaacac tgcacagttg
     4801 gttgacagcg tgcaacaact gattcactgc aatagccgcc gtaatattca tcacagttgg
     4861 aaaagtatca ttggagcttt gactgtgatt cacatcatca ttcggtaaga tcggcaagtc
     4921 ggggttgagt tttgcagctt ggtggctaat gacttcgttc acattcatat ttgtttgcgt
     4981 gccagacccg gtttgataga catgcagtgg aaaatctttt tgcagttttt cgtctggcaa
     5041 agccaacaag gcatcgactg ctcgcgtgat taattggcct tttggtgccg gtaaaacatc
     5101 agcggccaca tttgctcgcg ctgccgcttt tttgagttgc agcaaggccc taatcactgg
     5161 catcggcatc aatggaccag cctgaaaatt atgccggctg cgctctgttt gcggtcccca
     5221 caaagcgttt gccggaattt caactggtcc taatgtgtcc gtttctgttc gatatttgct
     5281 catgtttacc tc
//
