LOCUS       c00034_JAKXDC0..       12670 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAKXDC010000031.1 Lactobacillus crispatus strain
            DZD_CM_31_S799-bin_2 CHMNGAEL_31, whole genome shotgun sequence.
ACCESSION   JAKXDC010000031
VERSION     JAKXDC010000031
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 15:53:25
            Original ID  :: JAKXDC010000031.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12670
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12670
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6294:8829]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6295..8829
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12670
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12670
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             2..397
                     /locus_tag="ctg34_1"
                     /transl_table=11
                     /translation="RVDDREKIMNEFKQVHQQPNKEAAIKVLHAFYDKWNRAYNHVIRN
                     LKEIEPDLLVFYSYPKQIRASIYSTNMIESFNNVIKRKAKPKAEFPNEQSLDTFIGIQA
                     MSYNERYFNRIHKGFGQVQDTLESYFD"
     CDS             complement(673..1713)
                     /locus_tag="ctg34_2"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKRPA
                     SKSKRVKTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNY
                     EFDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLI
                     DVLRKM"
     CDS             2039..2185
                     /locus_tag="ctg34_3"
                     /transl_table=11
                     /translation="MIRSIKMKGMRTLIKLLLIGGSFLTLGLMAISSVLINKPAVAKVK
                     HRH"
     CDS             complement(2283..2975)
                     /locus_tag="ctg34_4"
                     /transl_table=11
                     /translation="MTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFPEFISTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(3041..3547)
                     /locus_tag="ctg34_5"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             complement(3513..3623)
                     /locus_tag="ctg34_6"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             complement(3679..4284)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_7"
                     /sec_met_domain="LysR_substrate (E-value: 1.7e-12,
                     bitscore: 37.3, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASRSGYFILNENTARLINTTDL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             complement(4286..4447)
                     /locus_tag="ctg34_8"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             complement(4463..5665)
                     /locus_tag="ctg34_9"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMELKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     ISYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPE
                     QNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRK
                     VAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDY
                     F"
     CDS             complement(5745..6281)
                     /locus_tag="ctg34_10"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDINMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             complement(6295..7197)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_11"
                     /sec_met_domain="OTCace (E-value: 5.5e-47, bitscore: 149.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 2.6e-20, bitscore:
                     63.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLTAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIHKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIIYN"
     CDS             complement(7158..7589)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_12"
                     /sec_met_domain="OTCace_N (E-value: 5.6e-38, bitscore:
                     120.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             complement(7600..8829)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_13"
                     /sec_met_domain="Amidinotransf (E-value: 2.5e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             complement(8903..9574)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_14"
                     /sec_met_domain="LysR_substrate (E-value: 8.4e-30,
                     bitscore: 93.8, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQPKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             complement(9580..9750)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     57.3; E-value: 3.9e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg34_15"
                     /sec_met_domain="HTH_1 (E-value: 1.1e-18, bitscore: 57.3,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     HYLKERHMVLS"
     CDS             9879..12179
                     /locus_tag="ctg34_16"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNAKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGKVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNRYIITINFIN"
     CDS             complement(12220..12534)
                     /locus_tag="ctg34_17"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVAFLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTSNYRIVDNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
ORIGIN
        1 acgcgtcgac gatcgtgaaa agatcatgaa cgaattcaaa caggtgcatc aacagccaaa
       61 taaagaagct gcgatcaaag tcttgcacgc cttctatgac aagtggaaca gagcgtacaa
      121 ccatgtcatc agaaatctca aagagattga acctgatctg ctggtctttt acagctatcc
      181 taagcagatc agggcttcaa tttactccac caatatgatc gaatccttta acaacgttat
      241 caagcgtaaa gctaaaccta aagcagagtt tccaaatgaa cagtcgcttg atacttttat
      301 tggcattcaa gcaatgagct acaacgaacg ctatttcaat cgaatccaca aaggctttgg
      361 tcaggttcag gataccttag aatcctactt tgattaaata aaagattaaa aaatcaatct
      421 acgagaaaaa tctatttaca caaaagattt gacagtttcc tcgaaacaca ttgcttttaa
      481 atagctcttt taaactcata cttctcctcc attaatcatt aataaaaata tttatcatcc
      541 tttaatctta ctacacgaaa ataatttttt acacatattt ttttaatttt taagctaaat
      601 catatttcat aaacataaaa taagactagt aatcaattca aattgactac tagtctcttt
      661 gtttaccaaa aactacattt ttcgcaaaac gtcgatcaat acacgacgta agtcttcgtt
      721 cttcttaccc atttcttcga tcaatctagc tttatcatct aaagcctgat tatatttatc
      781 ttgcaaagca ttatatcttt gctccagttg attgtaattt ctgattactg tattgtagcg
      841 ttcacgcaaa ccgctagctt catcaaattc ataattattc cgattatcat aattatttcg
      901 attattatag cggcggttag actgattatt acgtgagcgg ttattatttt ctcttctgat
      961 ctcaaaagga tgcttatttt gtcgcttacg ttgattttgc gtttgattat tattatttcg
     1021 attattgcta ttcttctgat tattcttacg ctcaaagtcc ttagattgac cttcacgact
     1081 ttcattctga tccttagaat gttgctcagg cttttcttta gtttctgttt ccttattttc
     1141 agccgctttt tcagcattct tgcgatactt ttgatcaatc ttgatatttt gataaaaagg
     1201 actaagttca gctataactt tttcaccatc ttcaaccgaa aaacttcccc gcttgttaac
     1261 tggcttaata aagttggtct tcacaattga agcaatctta tcctctaatt tcttttgaat
     1321 agatttatca atcttatcat tctttataac tttagctaaa atcttacgct tagtaattgt
     1381 cttaacccgc ttagatttag aagctggcct cttatcagta gcatcctctt tagctggggc
     1441 ttccttagca cgacgttcaa ttgcatctgc gtaatcttgt acattaccaa taattaattt
     1501 agcaacagcc ggcttaaaat attttcttct tcgcacagta atacttggtt gtttacgtgt
     1561 acgcacaaag ttataaattt taatctttag tttttgttgt aattctttac ttgcattagg
     1621 caacaattga tcaatcattt gattcattgt taccatttca tttaaatcaa tattttgttg
     1681 ttctaataat gtttgctcta ctattcctgg catttccaat cctatattct tttaattttt
     1741 tcacaacaaa aagggccatt acggcctatt ttgcaataat acatcaattt tctcattaat
     1801 aaacttaatg cactttccat tttacaacat taacgctatt tacgaaaagg gctacaagca
     1861 tattctctat tttttaacca aaacaagcag catcccatcg atactgcttt attttatgcg
     1921 cagttgcact agactttgac tctatttcta ttttacgtgc taaccagcct tttttctagt
     1981 tttattttct taactaatcc attaggtttt acatataaat tcttaatatt atttcgctat
     2041 gataagatca attaagatga aaggaatgag aaccttgatt aaactactct taattggtgg
     2101 atcattttta acgcttggtt taatggccat cagctcagta ttaattaata aaccagcagt
     2161 agcaaaggta aaacatcgcc actaaaaacc agaataatat atgttaataa atcttttccc
     2221 ctctaactag aaagaccagg ttatgtactc cacatagcct ggtcttcttt tcgtcttatt
     2281 ctttatggtt ggtagaaaat tgcaccttgg tcaacaatta catctggttg caacttacgt
     2341 aaactcttac tttcaacaca atattttgta ttattcaaat actctttgaa gttcttagtt
     2401 tccaagtgct gcttgtaagc ttcattatta cgataaactt caatagctaa ccattcattt
     2461 ggttgatcgg caacagttcc tgcaatcatt gccaaaatat ctttttcttc ttcgactgcc
     2521 gttttcattt ctttcattac agcatgagca aactcatcgc ccttacctaa agaaacacca
     2581 atttcagtca gataaataac ataatcattt gatccggtaa ctgctagttt ttctgccttt
     2641 gtagaaataa attccggaaa caattctacc tttactcgac tagttaaaat atctttagca
     2701 acgtcagtaa aatccttaaa ttgctttgaa ttagcatgag tatcataact tgcttcgtct
     2761 tgatagcatt ctactacaaa attagtagtt tcttcgtcat gacttgtctg cataaacaat
     2821 gtgcctggtt cgttctcttg agaagtaagc atattatgtt gccctgcctt aacgaacttt
     2881 gcatgatcct ctttattagt ttctagttta tataaacgca aaattggtgt ttgttttaat
     2941 ttcataactt ctcctccaag aattaatttt gtcattatta tactaaattt tatcgcgtct
     3001 attagtaaaa aacatccctt agttaaggga tgtcacaaaa ctataacgtg taattaactt
     3061 tcttaaactt gtagtccttc atttttttag ctaatttctt gcttctgaag tagttaccac
     3121 catcatatct actagaataa accagcacgt tatgcttttt accattaatg gtttgtggta
     3181 ccactcgata aagactccaa ttttcaaaag taatccacgg atcaatctca tagaatgtat
     3241 cattcttcat tttggtagtt ttaccagaca tccagttttg cgttacctta tcaaagttct
     3301 tctggttagc aattctacca ttgaagtaat cactaattgt cgaagcctcc tgggtaaata
     3361 ttggtttgcc attaacagta tgttcagtaa aggtgatctt tgtgccatta tgtgcattac
     3421 gatcataaga gtaccaagta ccctgcatct tttttggaat agtaacctgt acaccattac
     3481 cataagttga agcatcaaca gtctcaactt gactagccaa accagttaat cctaaaacaa
     3541 gtaccattga tgttaaaggt aacaaagttc tttttagcat aaaaatcatc tccagaatgt
     3601 aaaatatatg agtccgcttt cataatatat tttacagtat cttatagtac ttagacaaga
     3661 tatttttaac tttacagatt aatattcttg ctgcaatagc tttataaact cactacttaa
     3721 cgctgaattt gacttataaa aagccattat cttttgcttt attaactgac catgatcaag
     3781 caagaaaagt ggctgcaaat ctgtagtatt aattaaccta gccgtattct catttaaaat
     3841 aaaatagcca gacctagagg cgaccaacag tgctgcttct tcgaccgagt tagaagcgat
     3901 gaattgactg ccaatttgat acaaatcttt aaataaatgt agctcactaa cctcttcttc
     3961 aggtttagcc acaataaaac aagtcatatc attgagctcg tctttttcaa tcatttgaat
     4021 gccattagga tacattccct tgggcaaaat tgccattaca ccagcttgag tcaattctgt
     4081 ttcatcaaag ttaagattct cgtcacgcaa atcattgatt gctatgtctg cttcatcttc
     4141 attcagtttt gcaaaagcac catcatgact agtcgcaagt agttttacat ctacattagg
     4201 atgttttaac acaaaatgct gcactgcctg atctaattcc ttacgaccta attggtcaaa
     4261 atatgcaatc tttaattccg tcattttatt tttcatccag cggtgcgtgt ccttcttctg
     4321 ctactcttct tttatcctta gtatcttcat gcttattaag tgccatcaag gcaaaaaaga
     4381 tcaaattcaa accactaact acaatgccaa ataattttat taaattgagt ttcttttctt
     4441 tactcatttt ttaacctcac aactaaaaat aatcataaaa tgatacatcg cctttaacga
     4501 aatctaattt tttgatgcgg taatctgtaa ttaatcctag tttaacagca gcattcatgg
     4561 ttagtctacc taatagcacc tgggtccacg cggtaattga tcccgaaaaa tcaaccaatg
     4621 catcttcctt acgttctacc gctaccttac gtccatgatt acttaattgc caaactccaa
     4681 tattccaagg acactgttca tcgctattga cttccagatt aaaatcacct tcttgcattg
     4741 gccgcataca agccaaaact ttttcaaaat caataattcg actcatcata taaggacgca
     4801 aatcaacttg gagttcgttt tgttcaggaa aaagttcagc tcgtaacgat ttctctggta
     4861 cgctcatttt aaattgctta acactgcccg cgtgcgaacc cataaaacca aacatactca
     4921 gtaatccctg cggcgtaatt gcgtacattt catcagctaa aaaagtattg tctctaatgc
     4981 gataaatcaa gtaactaatt ggccgctcat ccgcgtcaaa ataaacggct acattgcggt
     5041 gatgataata agaatcaagt ctattccacc accatgcctc acgtacaacc gtgttacgtt
     5101 catcatcagt atgcagttga cgttcataaa gttgaatcac accattttga acagctaaat
     5161 tgtcccactt gccacgcact atatgaccag aacgtggtaa tttaaaacta cgcaatgcgc
     5221 ttccatcaaa gcgatattct ttttgataaa tactattgct aaacccgtac tggcgataaa
     5281 agctctccga aaatggtgcc aggttagcaa acggaatatc ttgcctatgt aagtcatgca
     5341 aaatttcttt cattaattgg gaaatatgac cttggccacg atactcagga tatgaagcta
     5401 cataacctat tccagccatc ggtaaatgat gcccaaaaac atcactttta aatcgattaa
     5461 ccataatata gctagctaat ttttccttat caaaatagcc ataacctgta ctatgatcat
     5521 aacgactcat aaaattttcg tctttagtca aatcattatt tttcaaaaat gcatattgaa
     5581 ttaatgccgt aatttgcttt aaattattct tatttttctt taattccatg cttattccta
     5641 tacgtacatc tataaattta ttcattacta ttttagttca ttttttaaat ttttaactag
     5701 atttttcata aaaataaacc ggaatcataa aatcccggtt tattttacgc aacgtattct
     5761 tgataaagct gagagataaa tgcctgcatc tgttccactg aatgtctccg gctgcgagca
     5821 cattctttag cagggcgatc acataaaaag cacttacgtg gctgcctgcc caaatctctg
     5881 cgtgaaattg cagcttgttt attttttacc aacacgtctg catcaaagag acgtcccaat
     5941 gatatctgat tctcaaaatc aattgttgag cgctttactt tttcaattga caaagataat
     6001 acataaaagt tttcacagcc actatcatca ttaagctgtg tcaccaattt aaaatgataa
     6061 cctaggttag tccaagcatt ttccagctca ttgataccca acataaacat tttagttaaa
     6121 tagcgattat tcttgattgg tcctgggata ttcatattaa tgtcgactag agtttgatta
     6181 ggatacttat taaaaatctt atgttgtaca gctactcgcc tatctttagc tgctaaaact
     6241 tgggcaatat cctgcttttt tccttcatta aaaatattca tttttatcac ccagttaatt
     6301 ataaatgatt gtgccgactc cgtctgctag tttgttggca ttgctcaaag aggtgataat
     6361 tgctaaatta cctgtttttt ctacaaattc aattgcagct tctatcttag gcttcatact
     6421 cccagctgcg aaataacctg ctgctagata ttgtttgagc tgttcaactt ttattttacc
     6481 aattgcttgt tgattttctt tgccataatt caaaaatgca tgatccaccg ttgttagaat
     6541 tactaattca tcagcgttga tatcttctgc cattttagca gcggaaaaat ctttatgaat
     6601 tacgccggca acacctctga gatgcccatc tttcacaata acaaggatgc caccaccgcc
     6661 acaggcaatc ggaataaata aatttcctaa agtagccgcc atcactgctt taattgaatg
     6721 caatcgattt tcagcttctg taaattgcca agcatacttt gaattaaaga cctcatcagt
     6781 tacttccatc tcatttaagc catatttttc atagatttct tctcccacct gagttgttcg
     6841 atcatgaaaa gctgtcaaac aatgcataaa gatcaattgg tcatctggtg taccagtcat
     6901 ttgcatcatt ttcattgtga ccgtatatgg ctttaataat ttaattcgtt cagaccaatc
     6961 attttcaccc atcgaaaccc aaacatcggt ataaacaaca ttggctcctt taacgccttg
     7021 agcaatatca tctgtgatca aattttttga acctgaatct tgggcaaaat tttgagcaat
     7081 tttttgtaca tcaggatgtg taaacaaagg cttgggtgta acaatatgta cattaacacc
     7141 taacattgag ccacaaacta aaagactgtc ggcaacatta tcgcggccat cacccacttc
     7201 caaacaggaa cgccagaata tttagccagc tcttctacat cttcttgagc aaaaccgcga
     7261 tattcaattc catcatacat tgagcctagg actttagccg tatccttgac gctttctttt
     7321 ttacctaagt ggatctcgct tgcgcctaga tattctggat gagcacctaa atcattacaa
     7381 gctactacaa aagcagatcg cgtcctagtt gaggcttttt caaaaagtag tgcaatattt
     7441 ttacctttca gatattcatg tgggatatgc tcttttttaa gttcttttaa atgtaatgca
     7501 aaatcaatta aatatgaaat ttcagctgga gtatagtctt tacaatcgag aaaacttcta
     7561 ccttgaaaaa cattttgtaa atatttcatt ttttgcctct tataaatctt cacgaatcaa
     7621 cggacacgac atacatctag gaccgccacg accacgtgag agttcactag accgaatctc
     7681 atgaacgatg atgccatgtt ttcttagcaa atcattggat acataattac gatcataagt
     7741 aacgacttca cctggtgcaa ttgccaaggt atttgagccg tcattccatt gttcacgtgg
     7801 tgcggcaatt ggatcaccac caccagttgg aattaaatcc aattcgctta aatgtaagtt
     7861 ttctttcaaa acctgcacca aatcattctt ttctgtgatt tttacaccgt tgtgatcatc
     7921 gggctgtaga acataaatat caattttgcc ggctttatct aaaataaagg gatgaaccgt
     7981 aaattgatta taattaatca ttgtaaaaac tgtatcaagg tgcatcatag catgattgtg
     8041 cggaatctta atcgctaaaa tcgtatcata acttgaatga tcaaataaat tatgagctaa
     8101 gtcagtaatt gcagttgcag aagtgcgttg tgaaatacct acagctaaca catggttatt
     8161 tagaactagt tcatccccgc cctcaaggcg accatgatga taacggtcac gccaaactgg
     8221 aatagttgcg ttcttgaaat caggatgatt tttcaaaatt gtttccataa ataatgattc
     8281 acgtcgtcta gctctgaaag tcatccggtt aatggtcatc cctgaaccaa ttgcagcctg
     8341 ttgatctcga gtaaaatata catttggcat tggatcaaga taaaaagggt aatctgggtc
     8401 ctcagccaaa tctgctaaag atggggtaga attatgaatc gcactttttc taattccagc
     8461 aatcaccgtt tttaccattt ccttagttag caattcttgg agatagttca gcaataattg
     8521 atgcaaagga tcctgttttt taatacttga ttcatccagt aactgatcta agaatgcccg
     8581 acgaactttc tcatctgtta aagattctgc taataaatcc tcaagatata atactttgat
     8641 cccctgctgc ctcaatacat gcgcaaaagc atcatgttct tcttgggcaa tcttcagata
     8701 aggaatatcg tcaatcaaca ttcgatgcaa aatatctggg gctagatttt ctagttcttt
     8761 tcccggtcga tgtaacatca ccgtttttaa cttaccaatt tctgaataaa catgaatcgg
     8821 actcgacatt caaccacctt ctattaatta ttgtacccgt ttacatttat tatggatcaa
     8881 ttaggtaaaa gttacagtat tatcatattg cagcaatgat ttttttcatt aaaggtgtaa
     8941 cttgatgatc tttacgccaa accagctgca aatgtgttat ccaattagca tgtttaattg
     9001 cgatcatatt ttcttgggca taagttgtcg caattgattc tggtactagc gctactccca
     9061 tttttctctt ggcccaagta attgctgtcc gtgaatcatc acacttaacc gcataaaatg
     9121 gtttaagccc atgatgtgca aaagtttgat taaaaatatc ctcaaagcga cgataaataa
     9181 tcaatggctg atctgctaga tctttaatgc gtaattcttt ttttggctga aaatctgggt
     9241 ctacactaat agccatcatt ttttcagttg ttaaagtctt agtatttaaa cctgtctggt
     9301 tgtaaggcgt tcgtacaatg cctagatcga ttgtcttttt ttctaattta tccaggatgc
     9361 cataagtatt atcttcataa atatcaaaag aaatttccgg ataatatttt cgtaattcat
     9421 taaaagaatt cattggtatc aagcccgttg aggaagatgc cattccaatt gcaatcgttc
     9481 ccaattcacc ggaaatagtc ttatgtactt ggttttcagc attttgagct agagaaataa
     9541 tttcattggc atagctttga aaaatttgtc ccacatcagt tagctcaata ccatgtgccg
     9601 ttcttttaaa taatgcgcgc ccaactcttt ctctaattgt tttaattgat agcttaatgg
     9661 tggctgtgca atatacaagc gcttagcagc tgctgtaatc tgcttttctt ctgctacaac
     9721 tagaaaataa cgtaactgtt ttagattcat attatttatc ctttttttat ttcaattgat
     9781 agtgatatta aaatatttaa tatcttatat tgtattttag tattttattc atagcaatat
     9841 ctgtgctacc ttattaaggt agatttggag ggaaaataat gtctgataaa tttcacggct
     9901 taactcaagc cgaagcagac aagcgcttaa aagaagatgg cttaaatgaa gtaccagagc
     9961 ctgaatacaa tttctttaaa gagttcttgt ctaagttatg gaacctatcc gcttggattc
    10021 tagaagctgc tttaattcta gaatgtatct tgggcaaatg ggtccaatca ttattcgtgt
    10081 tgttgatgct tttatttgct gcatttaacg gtgcatctaa gaaaaagcaa tcaagacgag
    10141 ttttaaataa tatttcacac aagttgactc ctactgtatc agttgaacgc gatggcaagt
    10201 ggatcaaact tgattctaaa caactagtta aaggcgattt aatctcactt aaacgcgggg
    10261 acgtactcgc agcagatgtt aaaattgttg acggtaactt agcttgtgat gaaagctcaa
    10321 ttacaggtga atctaaacca gttaagaaag caattgatga caccgccttt gccggtacta
    10381 cagttgttga aggtgatggc ctagctgttg ttactgctac aggtaaagat tctagaagcg
    10441 gtaagacgat taatttgatc aacaattccg ctgctcctgg tcacttacaa caacttttga
    10501 ctaagattat ctactacctt tgcttactag atggtgtttt aaccttagtt attattatcg
    10561 cctccttctt caaaggcggt aatttcaata cctttattaa tatgttgcca ttcctggcaa
    10621 tgatgtttat tgcttcaatt cctgtagcaa tgccatcaac ttttgcttta tccaactcat
    10681 ttgaagcaac ccgcttaagt aaagaaggag tcctgacttc tgacctaact ggaattcagg
    10741 acgcagctaa cttgaacttg cttttacttg ataagactgg aacaattacg gaaaacaaaa
    10801 ctgccgtagc cgcttggact gatctaagtg acttgcctga caaagacgtg cttgctttag
    10861 ctggagccgc aactgataaa cgtaatgctg gtattatcga tacagcaatc gatgaatact
    10921 tagtagaaaa taacattcca gtcatgaatg ctgaaaactt tactccattt acttctgaca
    10981 ctggttattc tatggctgat gttgctggac ataatgcaaa gcttggttca tttaagcaat
    11041 tatctttgat cgataaacat gccgatgaag aaatttctgg aattaatttc aaggcaggac
    11101 gctcagtggc agtcttgatt gacgataagt tagctggtgt cttcatctta caagataaag
    11161 ttagaacaga ctctaaagca gctttggctg aactcaagaa acgtggcgtt cgcccaatta
    11221 tgttaactgg tgacaatcaa aagaccgctg ctgcagtggc agaacaagtt gatttaactg
    11281 gtaaagtaat ttcgattcac gatttcaatg aaaatactga tattaatgat ttggccggta
    11341 ttgctgatgt tttaccagaa gataaactca agatggtaaa gcttttccaa gaaaaaggct
    11401 atatcgtagg gatgacaggt gacggagtta acgacgcgcc tgcattaaaa caagctgaag
    11461 taggaatcgc agtttcaaat gctgctgacg tagctaagcg ttcgggtaaa atggtattac
    11521 tagacgatgg tctaggctca attgttaaaa ttttagacgc tggacatcgc gtataccaaa
    11581 gaatgactac ttggtcacta accaagcttg ctagaactgc tgaattaacg atgctgttaa
    11641 cttttggcta tcttttcttt gactacatcc caatggcctt gaatgcaatg gttatctata
    11701 ccattatgaa caatatggtt acgatgatga ttggaactga caggactcac attacttata
    11761 agccagaaaa ctggaatatg gctaagcttg ctaagatcgc cttttcacta gctgctggtt
    11821 ggactttaat tggtattggg tttgtttggt tcttaaacac acacggttgg agtcacggtg
    11881 ctgtttctac tatggtttac gtatacctag ttcttagcgc aatgttgatt gttttgatta
    11941 ctagaactcg taagtacttt tggcaagatt acccatccaa gttggttggt agtgttcaaa
    12001 ttgcagatgt tctattgacc tttatcttag ctctttgtgg ttgggcaatg gtccagattt
    12061 ccattcaaaa cttagcaatt actgtaattg tagcgattat tgctgccata ataatcgact
    12121 taatttacca acctgtgatg aaaaacaggt atattattac cataaatttt ataaattaaa
    12181 agacttctag gaactttgaa ctcttagaag tcttttaatt tatctttttg attcacgata
    12241 tcctgctgca cgtgctgctg ctttactctt gaagaaaact gcattttcac gattcattcg
    12301 ataattatga ccgcgcatta cgtgaaagat ttttgatcgt ttattatcaa caattctgta
    12361 attactggta taaatcttag ttttatcacg atattgatgc tttctccttc tgtgatgaat
    12421 agctgcatta acaactgatg tcgacccctg caaatttgca ggcagaacac tgatttctcc
    12481 cactaacatc agaaatgcaa caatagtcac aacccaattc ttgcatcttt tcataaaaac
    12541 actcccttaa tatgtcacta tatttatata gtatacgttt atatatgaag tgttcctacg
    12601 tttattagaa actagtttga aactgtcaaa tcttttgtgt aaatagttct ttctcgtaaa
    12661 ttgatttttt
//
