LOCUS       c00054_JAKXBQ0..       13191 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAKXBQ010000058.1 Lactobacillus crispatus strain CM_G08_S831-bin_2
            FKEFEFDL_58, whole genome shotgun sequence.
ACCESSION   JAKXBQ010000058
VERSION     JAKXBQ010000058
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 10:02:45
            Original ID  :: JAKXBQ010000058.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13191
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13191
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4289:8191]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4290..8191
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13191
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13191
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(36..182)
                     /locus_tag="ctg54_1"
                     /transl_table=11
                     /translation="MTELHYDIVGSFLRPAELKKARAEFEEGKIKQEELTHVENKEIPE
                     LSN"
     CDS             complement(432..593)
                     /locus_tag="ctg54_2"
                     /transl_table=11
                     /translation="LVQADVVDSNEYGLGAILKSKLLSKQFTSDDRYPVRVFPILGALS
                     KELVVKLT"
     CDS             874..1359
                     /locus_tag="ctg54_3"
                     /transl_table=11
                     /translation="MSKFEILKLMAFASLFAVMTFILVVVFVGNRRAAKYDERQELIRG
                     RGDRYGFLVLIVGEVISALFMQTDFYTKHGIAVNFAIIMLSLTVMSVYDIVHGAYFAFN
                     EEHVKANSWLYVVLGICLILGYIDDFNSALNIMGIYWLIIGVVSLFQLHRDKESDKD"
     CDS             1356..1553
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 57; E-value: 5.2e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg54_4"
                     /transl_table=11
                     /translation="LKNLKMKAARVGKDLTQEDLAQQIDVSRQTISAIEKGNYNPSINL
                     CIKICQALDKTLDDLFWPEG"
     CDS             1538..1657
                     /locus_tag="ctg54_5"
                     /transl_table=11
                     /translation="LAGGIVLVQYRSFFAKYDQNGARFDELIFDKQNRFMIFL"
     CDS             1928..2074
                     /locus_tag="ctg54_6"
                     /transl_table=11
                     /translation="MKKLNEKELVEVKGGFADPTVSFFALNDITINKKHRNHFNWKKIF
                     GLK"
     CDS             2078..3484
                     /locus_tag="ctg54_7"
                     /transl_table=11
                     /translation="MFFQALFSPVIDLYIFYRLSGWKFKREDYAFSIVFIGTCVLAGSV
                     VQIDDFLVDIIQAFLIFLFSYLVKKEKKVKFIFGAILFFELLDLLITISAEIILLIFDI
                     SSSSMTFVFLLVEFVIIVIIQKYYLKIRKLLNDRNSSIFIGLIFYVYLSSSIVYFLALK
                     STHMTIVFEVSLSLLVLQIVFSVITYIAIIKVQKGLLTKQEQKEQKFQLELANADRKAK
                     EAENKELILKQQQLSSEMEQLQEYSNYLDKNEDDLHRFKHDYQNILNGLKVSAQEGNTA
                     EVVKILDQYTETQFNKKALRKYNGVNHIHEKNLKSIAIAKLSKLYSLGLDYSFDCEHDI
                     SRIPDSVNILDLVRIIGITFDNAAEESQALIKETGNSNSARIDAMYYQENGDFEFEIRN
                     RVRKSGVATDKISQKNYTTKKHHMGLGLANVKEITHKYEDSMIVNYYVDDGWFTFDLTI
                     LPDSESGTEK"
     CDS             3488..4312
                     /locus_tag="ctg54_8"
                     /transl_table=11
                     /translation="MQYPVFICDDDQNQIEQTKKILGAAEMILSDDEEIEFSIASATDY
                     MGAIDYLKKHKLDGGIYFLDVELGGDTEEDTGFDLAALIKKRDERAQIIFVTSHADLSL
                     ITFRRRLGPIDYIVKTSDLDKFRQMMVKTVEVAIYNLHKFNYMKKMTFSYKIGRQTRNV
                     NIDDIIYISTTITPHKLLMILTTGEMQLLGSINQYAKENPMLEKINQSCLVNPKNIESI
                     DLKQHRVSFVNGDVEDFSRSSVKMMKDFLARYNYKTEKLAKQKEINDGHVNV"
     CDS             4290..6455
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     249.8; E-value: 3.4e-76)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 319.4; E-value:
                     7.8e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_9"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1076.8,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.9e-45, bitscore:
                     145.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMGMLTYKSIYVPQIDETDCGAACLAMILKNYHSQVSIAHLRHIA
                     KTNTEGTTALGLVKTAEKFNMDVQAVKADMSLFNMKDIQYPFIVHVIKDGGLLHYYVVL
                     KSTKRKIIVADPDPTSGIKKMSKKAFEKEWTGITLFMVPKADFKPVKEKKNNLLSLFPY
                     MFKQKKLVRNIILAALLMTLISICSSYFVQGLIDTYIPNGTFTTLSVLAIGLLIAYVFN
                     SIFSYGQQFLLNVLGQRLSIDLNLQYIKHIFELPMEFFTTRKTGEITSRFSDASRIIDA
                     LASTVISLFLDLSIVILMGIILAVQNMTLFLITLASLPLYAIVILGFSKRFERLNNDQM
                     ESNAVVSSSIIEDIQGIETIKALNSEQVRYRKIDSQFVDYLKKAFKYSKTEAFQTALKT
                     FIRLSLNVIILWVGASVVMHNQMSIGELMAFNALLSYFIDPLQNIINLQPTLQAANVAQ
                     NRLNEVYLVQSEFKGKTSVNDSHDLNGDINFSHVDYRYGYGEDVLKDINLTIKDNEKLT
                     IVGMSGSGKSTMVKLLVDFFSPTKGKVTFNGHSTRSINKHVLRSYVNYVPQTPYIFAGT
                     IKENLLLGSRKNITEKEIEEACQIAEIKNDIEKLPLGFNTQLDENAKILSGGQKQRLTI
                     ARALLSPAKVLIFDEATSGLDTITEKKVVDNLIRLKNKTVIFIAHRLAIAERTDNIVVL
                     NQGQVVEQGNHNELMKKRGYYYNLVKS"
     CDS             6465..6728
                     /locus_tag="ctg54_10"
                     /transl_table=11
                     /translation="MSDQDLESSKFYSYKFRNFSTMIILPAFILVILLFLGSFFAVHEN
                     VVNSMGVITPDHVLSLQNRAYREGQKLSKGINLTLANGKKEY"
     CDS             6749..7102
                     /locus_tag="ctg54_11"
                     /transl_table=11
                     /translation="LDNKDSVAMPDIKNRRKLRVVTYVPSSEVAVLNKGQQVRFQIENK
                     QGMSEILNGKIISIGTYPVQQKGMSMFEVETMLKTTKSERKFLRYGMQGKVSIITGKAS
                     YFNYIKSKLLNSK"
     CDS             7310..7489
                     /locus_tag="ctg54_12"
                     /transl_table=11
                     /translation="MESTVNFEKLNSNKLVSVVGGSHSRNYYNGRGTGRNIRAAGTVAN
                     VIWTGAKIISHFLG"
     CDS             7834..8007
                     /locus_tag="ctg54_13"
                     /transl_table=11
                     /translation="MKDYLMLLVNISFLVTWFYTPKTQIGTWVAAIVAVVALIVDTVDI
                     INFIFKSRKRNE"
     CDS             8051..8191
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_14"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.5e-10,
                     bitscore: 33.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFQKLSTAELQNIVGGRGKSSWWRNVQRGVSQFMSGLRDGLAG
                     K"
     CDS             8216..8362
                     /locus_tag="ctg54_15"
                     /transl_table=11
                     /translation="LTLDQLKNTIGGKGHSRNYYAGRNFGRTLRNVSQMLNSSMRPISI
                     WNV"
     CDS             8444..9241
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_16"
                     /sec_met_domain="Abi (E-value: 1.1e-17, bitscore: 56.0,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNNKYYLALADEVEFSNKAEVNKTIRNLFILAIILLIGSFVLPHL
                     IVGNMITKWLIVIIFIVAFAYVAEHFILTTKTFNQRLKLQGISKVMMIIYCVFLALILF
                     GALKDKILLFKLPLYQIMVAALAAILPAICEEFLFRGILFNTFLLVFRKEKYDILWTSI
                     VCSILFGLYHLNNLTSQSLISTVGQVIITLGMGLFLSYLRVWSNGLIWCMVVHFLQDFS
                     PKILSTDYGTSKIKLTVLVATLIVILMLICIYTINRRFLELSN"
     CDS             9319..9591
                     /locus_tag="ctg54_17"
                     /transl_table=11
                     /translation="MENAKELKSLLVGVKQKVVEDSAAVELINHALSNLEQGVNIEKVV
                     FDLKRDLNNYSLSHNFKLPQPLTELQLKLNENSNKWRDAGLTGSI"
     CDS             complement(9672..11468)
                     /locus_tag="ctg54_18"
                     /transl_table=11
                     /translation="MAIPNRNEVPEELKWDLTRIFKNDEEWEQAYAAAQEKIDQLGELK
                     GTLAKSGKDLYEGLTKILAVKREVENIYVYATMSSDVDTANSHYLGYVSRVQSLANQFE
                     AATSFINPEILSIPSDKLAEFKQAEPRLKNYAHYLEMITNKRPHTLPAEQEKLIADAGD
                     ALGVSENTFNVLTNSDMEYGYVQDDDGNMEQLSDGLYSLLIQSQNRDVRKGAFDTLYAT
                     YSQFQNSLASTLSGVVKKHNYNAKAHKYDSARQAALAENGVPEAVYDTLIQEVDSHLDL
                     LHRYVALRKKILGLKDLQMWDMYVPLTGKPSLSYNFEEAKEVAKKALKPLGEDYLKHVD
                     YIFNNRVIDPIESKNKVTGAYSGGAYDTDPYELLNWEDNIDSLYTLVHETGHSVHSWYT
                     RNTQPYVYGDYPIFVAEIASTTNENILTEYFLDHITDPKTRAFILNYYLDSFKGTLFRQ
                     TQFAVFEQFLHEADANGEPLTADTLDDVYGQINQHYYGDSVEPGGDIALEWSRIPHFYY
                     NFYVYQYATGFAAATALANKVVHGTPAERDAYLGFLKAGSSDYPTEIMKRAGVDMTKPD
                     YLEDAFKTFEKRLNEFESLIEK"
     CDS             11636..12874
                     /locus_tag="ctg54_19"
                     /transl_table=11
                     /translation="MDQNPKRREDYRARRSSLNLHRNRAFAADAPALKPGNFLARLVGV
                     VALLAVCFGVAWAAHMYFTVHSVIDSKNGGNTATSAKIVNRQPISILVLGVDQGIEGRH
                     DRGNSDTMILATANPQKNSATMTSIPRDTLADIKGDPGDKYFMFRVNSAYEIGGHESSM
                     KTVSSMLNVPINYYLEVNMKALKSLVNAVGGVDVNVPFDFSYDWCDFHKGKQHLNGRHA
                     VAYVRMRKEDPRGDYGRQMRQRQVIEAIAHKAMSVNTLSNYRKLVDVFNKYVKTNLTFN
                     DMLSLALNYRGCMKNMKSSYIQGHDAWIDGASIQVASTKELQKTSDRIRKNLNLSTQTL
                     NNEETRQNELNDQNNHIKWDDPQAFTNYQIYDQNQDKPASGSNSGYGEGTGTGSSSSSS
                     SSSSSSSGWHFHW"
ORIGIN
        1 aagcaatata tctcttcata acctaactgt tgcacttaat ttgacaattc agggatctct
       61 ttattttcaa catgagttaa ttcttcttgc ttaatctttc cttcttcaaa ttctgcgcga
      121 gcctttttta attctgcagg tcttaaaaag ctaccaacga tatcgtaatg taattctgtc
      181 ataatttttc tccttagttt tgcttcgatg ttttatttaa cgatgaaaag tccgatgatg
      241 atcaagatca accagacaat agtgcacatt cggttgaatg cctttttact gatgatgatt
      301 tgtgaacttg tagttttgat aggtttatcc attgtctggc tcctttctga aaaattaaat
      361 aagcaaaata aaaagcgccc ttagcataga atttctatgc tagggacgcc taagcgtgtt
      421 accacccaaa ttcaagttag cttcacaact aactccttac taagtgctcc caaaattggg
      481 aatactcgga cggggtaacg atcgtcactc gtaaattgct tacttaatag cttgctcttt
      541 aaaatagctc caagaccata ttcgttacta tcgactacat cggcttgcac caactccgac
      601 tctctgcaga agtcttaagt aattactcat ctcttctaag cttttattaa tttaattgtc
      661 attataatac gacgatgaaa agaagaagtc aaggaaattt ttgaaaaatc aggatcatta
      721 acaaataatc ggtatcaaat ctcacgaaat gataccgatt atgttaatgc tagtttttat
      781 aaatacaaat ttattagtaa aaatgtaaaa catactttac attttgcaaa tatgggctta
      841 atatcaaact attaaaagaa agggatgtgt aaaatgtcaa aatttgaaat attaaaatta
      901 atggcttttg caagcttgtt tgcagttatg actttcatct tagtcgttgt attcgtggga
      961 aatcgtcgtg cggcaaagta tgatgaacga caggaattga ttcgtggtcg tggtgacagg
     1021 tatggctttc ttgtgttaat cgttggagaa gtaatttctg ctttattcat gcagacggat
     1081 ttttatacaa agcatggtat tgctgttaac tttgcaatta ttatgttgtc attaacggtg
     1141 atgtcagttt acgatatagt ccatggagca tattttgcat ttaatgaaga gcatgttaag
     1201 gcaaatagtt ggctatatgt tgtacttggt atttgcttga ttctaggata tattgatgac
     1261 tttaacagtg cgctgaacat tatggggatt tattggttga ttattggagt agtaagcctg
     1321 tttcaactcc atcgtgataa ggaaagtgat aaggattgaa aaatttaaaa atgaaggctg
     1381 cacgagtcgg taaagactta acgcaagaag atttggcgca gcagattgat gtttcaagac
     1441 agacaatttc tgcgattgag aagggaaatt ataatccctc gattaactta tgtatcaaaa
     1501 tttgtcaggc gctggataaa acgttggatg atcttttttg gccggaggga tagtactcgt
     1561 acaatatcga tcattttttg caaaatatga tcaaaatggt gcaagatttg atgagctgat
     1621 ttttgataaa cagaataggt ttatgatttt tctataataa tttttaagta aaggagagga
     1681 agatcatgcg aaaattgtcg acttcgattc tagaaaaaat tgttggagga cggtcaaaaa
     1741 ttagacggca tttcttcaag agtaattctc ggggatgggg aaatggttct ggtggaggaa
     1801 cattttaaat gaaaatgcag aatatgattt gaatggtgca aaatttgacg actttagttg
     1861 tgagattatg tgtgtagtaa cattaatagt gtaaaaattg ttagttaatt gaaaggaaat
     1921 ttgaattatg aaaaagttga atgaaaagga attagttgaa gttaagggtg gatttgctga
     1981 tcctacagtt agtttttttg ctcttaacga tatcacaata aataaaaaac atagaaatca
     2041 ttttaactgg aagaaaattt ttggattaaa atagaaaatg ttttttcaag ctttattttc
     2101 tcctgtaatt gatttgtata ttttttatcg attgtcaggc tggaagttta agagagaaga
     2161 ttatgcattt tcgatagttt ttattggaac atgcgtatta gctggtagtg tagtacaaat
     2221 agatgatttt ttagtagata ttattcaagc gtttttaata ttcctttttt catatttggt
     2281 aaaaaaagag aaaaaagtaa aatttatttt tggggcaatt ttattttttg aattattaga
     2341 tcttcttata acaattagtg ctgaaataat actattaatt tttgatatta gttctagtag
     2401 catgactttt gtatttttgc tagtggaatt cgtaattata gttataattc aaaagtatta
     2461 tttaaaaatt cgtaagttac taaatgatcg aaatagttcg atttttattg gattaatatt
     2521 ttacgtttat ttatcaagct ctattgtgta ttttttagca ttgaaaagta cacatatgac
     2581 tatagttttt gaagtgtctt tgagtttatt agtgcttcag atagttttct ctgtaattac
     2641 ttatatagct atcattaaag tgcaaaaagg ccttctaact aaacaagaac aaaaagagca
     2701 aaaatttcag cttgaactag caaatgctga tagaaaagca aaagaagcag aaaataagga
     2761 actgattctt aaacagcagc aattgagttc tgagatggaa caattacagg aatattcaaa
     2821 ttatcttgat aaaaatgaag atgatttgca tcgtttcaaa cacgactatc aaaatatttt
     2881 aaatggctta aaagtaagtg ctcaagaagg taatactgca gaagttgtaa aaatacttga
     2941 tcagtatact gaaacgcaat ttaataaaaa ggctttgcgt aaatataatg gtgtaaatca
     3001 tatccatgag aagaacttga aaagtatcgc aattgctaag ttgtctaaac tttatagttt
     3061 aggtctagat tatagtttcg attgtgaaca cgacatttct cgaattcctg atagtgttaa
     3121 tattttagat ctggtcagaa taattggtat cacgtttgat aatgctgcag aagaaagtca
     3181 ggccttgatc aaagaaacag gtaactctaa tagtgcgcga atagatgcaa tgtattatca
     3241 agaaaacggc gatttcgagt ttgaaattcg aaatcgcgtt agaaaaagtg gagtagcgac
     3301 agataaaata agtcaaaaga attatacaac caagaaacat catatgggtt taggactagc
     3361 gaatgtaaaa gaaattactc ataaatatga agattcaatg attgttaatt actatgttga
     3421 tgatgggtgg tttacttttg atttaacaat tttgcctgat agtgaaagtg ggactgaaaa
     3481 ataaaaaatg caatatccag tatttatttg tgatgatgat caaaatcaaa ttgagcaaac
     3541 taagaaaatt cttggtgctg cggaaatgat tttgtcagat gatgaagaaa ttgaattttc
     3601 aattgcatct gcaactgatt acatgggtgc aattgattat ctgaagaaac ataaattaga
     3661 tggtggtatc tactttcttg atgttgaatt aggcggtgat acggaagaag atactggctt
     3721 tgatctggct gccttaatta aaaagcgaga tgaacgagct caaattatct ttgtaactag
     3781 tcatgcagac ttatcattaa ttacattcag aagacgatta ggtccaattg actacattgt
     3841 aaaaacatct gatttggata aatttagaca gatgatggta aagactgtag aagtagctat
     3901 ctacaactta cacaaattca attatatgaa gaaaatgact ttttcgtata aaattggacg
     3961 tcaaactagg aatgtcaata ttgatgatat tatttatatt tcaacaacta taaccccgca
     4021 caagttatta atgatcttga cgacaggtga aatgcaactt ttaggtagta ttaatcaata
     4081 tgctaaagaa aatcctatgt tagagaagat taaccagtct tgtttggtga atccgaagaa
     4141 cattgagtcg attgatttga aacagcatcg tgtctcattt gttaatgggg atgttgaaga
     4201 tttttcacgt agtagtgtga aaatgatgaa agattttctt gctagatata attataaaac
     4261 agagaaatta gctaagcaga aagagataaa tgatgggcat gttaacgtat aaatcaattt
     4321 atgttccaca aatcgatgaa acagactgtg gtgcagcttg tttagcaatg atcttaaaga
     4381 attatcattc tcaagtatca atagcacatt tacgtcatat tgctaaaacc aatactgaag
     4441 gaactactgc tttaggatta gttaaaactg cggaaaaatt caatatggat gttcaagcgg
     4501 taaaagcaga tatgtcctta ttcaatatga aagatattca atatcctttt attgttcatg
     4561 tgataaaaga tggaggattg ttacattatt atgtagttct taaaagtact aaaagaaaaa
     4621 taatcgtagc cgatcctgat cctactagtg gaattaaaaa aatgtccaaa aaggcgtttg
     4681 aaaaagagtg gacaggtatt acattgttta tggtgcctaa ggcagatttt aagcctgtaa
     4741 aggagaaaaa gaataatcta ttatcattat tcccttatat gtttaaacag aaaaagttag
     4801 ttagaaacat tattttagct gctttgctga tgacactgat tagtatctgt agctcatatt
     4861 ttgtacaagg gttgattgat acatatattc ctaacggtac atttaccacg ttatctgttt
     4921 tagctattgg gttattgatt gcatatgtct ttaactcaat tttttcatat ggtcagcaat
     4981 ttttattgaa tgttttgggg cagcggttat caatcgatct taatttacaa tacattaagc
     5041 atatttttga attaccgatg gaatttttta ctaccagaaa aactggtgag attacttctc
     5101 gtttttctga tgcaagtaga attatagatg cattggcaag tacggtgatt tcattattcc
     5161 ttgatctttc aattgtaatt ttaatgggta taattttggc ggttcaaaac atgacattgt
     5221 ttttgattac gctagcttca ttaccactct atgctattgt tattctcggc ttttcaaaaa
     5281 ggtttgaaag attaaataat gaccagatgg aaagtaatgc ggtagttagt tcatcaatta
     5341 ttgaagatat tcaaggaatt gagacgatta aagcattaaa cagtgaacaa gtacgttatc
     5401 gaaaaattga tagtcagttt gttgattatt taaaaaaagc ttttaagtat agcaaaacag
     5461 aagcttttca aactgctttg aaaactttta ttagattatc actgaatgtc attattcttt
     5521 gggtgggggc aagtgttgta atgcataatc aaatgtctat tggtgaattg atggcattta
     5581 atgcattatt atcatatttt attgatccat tacaaaatat tattaacttg caacctacac
     5641 ttcaagctgc aaatgtagct cagaatcgtt taaatgaagt ttatttagtt caaagtgaat
     5701 ttaagggcaa aacttcagtt aatgatagtc atgatttaaa tggagacatt aatttctcac
     5761 atgtcgatta tcgttatgga tatggtgaag atgtcttaaa agatattaat ttgacgatca
     5821 aagataatga gaaattaact attgtgggaa tgagtggatc aggtaagtca actatggtta
     5881 aattgttggt tgattttttc agtcccacaa aaggaaaagt aacttttaat ggtcattcga
     5941 ctagaagtat aaataagcat gttttacgct catatgtgaa ttatgtgcca caaactccat
     6001 atatttttgc aggtaccatt aaagagaatc ttttgttggg aagtcgtaag aatataactg
     6061 aaaaagagat agaagaagct tgccaaatcg cggagataaa gaatgacatt gaaaaattgc
     6121 cattaggatt taatacacaa ttagatgaaa atgctaagat tttgtcaggt ggtcagaagc
     6181 aaagattaac aattgctagg gccttacttt cacctgctaa ggtattgatt tttgatgaag
     6241 caacaagtgg gcttgataca attactgaga aaaaagtggt tgataattta attaggttaa
     6301 agaataaaac tgttatattt attgcgcatc gtttagctat tgctgagaga actgacaata
     6361 ttgtggtatt gaatcaaggt caagttgtag aacaaggtaa tcataacgaa ttaatgaaaa
     6421 agcgtggcta ttattacaat ttggtgaaaa gttaggtgat attaatgagt gatcaagatt
     6481 tggaaagtag taagttctat tcctataagt ttcgcaactt ttccacgatg ataattttgc
     6541 cagcctttat tttagtaatt ctattatttt tgggatcttt ctttgctgta catgaaaatg
     6601 tggttaatag tatgggtgtt atcacgccag atcatgtatt atctttgcag aatagagcat
     6661 atagagaggg gcaaaaactg tcaaagggga ttaatctcac cttagctaat ggtaaaaaag
     6721 agtattaaaa gataatgcta ttgtccattt ggataacaaa gatagtgttg ctatgccaga
     6781 tataaaaaat aggagaaaac tgagagtagt aacatatgtc cctagttctg aagttgctgt
     6841 acttaataaa ggacaacaag tgagatttca gattgagaat aagcaaggaa tgtctgagat
     6901 acttaatggg aaaattatta gtataggtac ttatcctgtc caacaaaaag ggatgagcat
     6961 gtttgaagta gagactatgc ttaagactac caagtcagaa agaaagtttt tgcggtatgg
     7021 gatgcaaggt aaagtgtcaa ttattacagg aaaagctagt tactttaatt atattaagtc
     7081 taaattgcta aattctaagt aaaattagtg agatgtcgat gattgaaact catatagtag
     7141 gcagttttgg atcaaattat gtactttagc agaatatgat gtggatgttg ctaacttatg
     7201 acaatgtcat agaaaatacc actattctgg taaagttata tatgtaagtt gataaggtac
     7261 ttagaggtac taagtgaggc aggcttaaag atttatcgga ggtatcaaaa tggaaagtac
     7321 tgttaatttt gaaaagttaa attcaaacaa attagtaagt gttgtaggag gtagtcactc
     7381 tcgaaactac tacaatggtc gtggtactgg tagaaatatt agggctgcag gaacggttgc
     7441 aaatgttatt tggactggag ctaagattat cagccacttt ttgggataaa atttaagtta
     7501 taggcaaaag tataagataa tattctttat tttagtagtt ttgagaaatt taactgctct
     7561 tctctataaa aaacttttgt ttagaagtgt tttattggat atcgttgctt taatttttta
     7621 tcaatataat atcctttaaa catgttattg tttgatttga tacattttat tagtgaacgc
     7681 atcctcgcgt atttcgatta taagtcaaat ttcaggggcg ttattcttgg actatatatt
     7741 tagaactagg aaactgatta agctgacgta aacaaggtag cttttaaagt aataagatga
     7801 aaggttaatc gatatcaact tggtaggaga aaaatgaaag actatttaat gttattagta
     7861 aatatttctt ttcttgtgac ttggttttat actcccaaga ctcaaattgg tacttgggta
     7921 gcagcaattg tagcagttgt tgcattgatt gtagatacag ttgacattat taactttatt
     7981 ttcaagtcaa gaaaacgaaa tgaataatta tcggtaaaga aatttgctaa ttagtattgg
     8041 aggtatagaa atgaataatt ttcaaaaact aagtactgct gaattacaaa atattgtagg
     8101 tggtcgtggt aaaagctctt ggtggagaaa tgtacaaagg ggcgtaagtc agtttatgtc
     8161 aggccttcgt gatggcttag caggtaaata aaaagaaagt attaaaatgg aagaattgac
     8221 gttagatcaa ttaaaaaata ctataggtgg taaaggacac tctcgtaatt actatgctgg
     8281 tcgcaatttt gggagaactc tacgaaatgt tagtcaaatg ctgaatagtt cgatgagacc
     8341 tattagtatt tggaacgttt gaaagttata agtaataagg ctaataaatt taattagaat
     8401 ttattagcct tattatttca tataaaagta ttagggtgaa acattgaata ataaatatta
     8461 cttggcatta gccgatgaag tagaatttag taataaggct gaagtcaata aaacaatcag
     8521 aaatctattt atacttgcaa tcattctttt aataggttca tttgtgttgc cacatttaat
     8581 tgtaggcaac atgataacca agtggttgat tgtaatcatc tttatagtcg cttttgcata
     8641 tgtagccgag cattttattt taacgactaa gacttttaat caaaggctaa aattgcaagg
     8701 aatatcaaaa gtaatgatga tcatctactg tgtctttttg gccttaatac tttttggagc
     8761 attaaaagat aaaatattat tatttaagtt gcctctgtat caaataatgg tagcggcttt
     8821 agctgcgata ttgcccgcaa tctgtgagga atttttattt agagggattt tatttaatac
     8881 tttcttgcta gtttttcgta aagaaaaata tgatatctta tggacatcta ttgtatgttc
     8941 aattctgttc ggcttatatc atttaaataa tttaactagt caatcattaa tttcaactgt
     9001 tggtcaagtg attattacat tgggtatggg gttattcctt agttatctaa gagtgtggtc
     9061 caatggatta atttggtgta tggtagtaca ctttttacag gacttttcac ctaagatatt
     9121 gagcacagat tatggtactt ctaaaattaa attgacggta ttggtggcaa cactgattgt
     9181 aattttaatg ttaatttgta tttatacaat taatcgtaga tttttggaat taagtaatta
     9241 aaatcgataa aaataatcgg tatcaaatat gctaaaatga taccgattat ttttatatga
     9301 gcgtgatagg agaacgatat ggaaaacgca aaagagttga aatcacttct agtcggtgta
     9361 aaacaaaagg ttgtcgaaga tagcgcagca gtagagctaa tcaatcacgc tttaagtaat
     9421 ttggagcagg gagttaatat tgaaaaggta gtctttgact tgaaacgtga tctgaataat
     9481 tattcattgt cacataattt caagctgcct caaccattaa ctgaattaca gctaaagtta
     9541 aacgaaaatt ccaataaatg gcgggatgca ggtctaacag gttcaattta aataaaaata
     9601 agtatcatca acaaaaaaat cgatatcaaa tcttacgaaa tgatatcgat tttttatatg
     9661 agcgcgatta tttatttctc aatcaagctt tcaaattcgt tcaaccgttt ttcaaaagtc
     9721 ttgaaggcat cttctaagta gtcaggctta gtcatgtcta cgccagcacg cttcatgatc
     9781 tcagttgggt aatcacttga accagcttta agaaagccaa ggtaggcatc cctctcagca
     9841 ggcgttccat gaaccacctt gtttgctaat gctgttgcag ccgcaaagcc agtcgcatat
     9901 tggtacacat agaaattgta gtagaagtgt ggaattcgtg accattcaag ggcaatatcg
     9961 ccgcctggtt caacgctatc gccgtaataa tgctgattaa tttgaccgta aacgtcgtct
    10021 aaagtgtcag cggtcagtgg ttctccatta gcatcggctt cgtgcaagaa ttgttcaaac
    10081 acggcaaatt gagtttgacg gaataaagtg cctttaaatg aatcaaggta gtaatttaag
    10141 ataaaggccc gcgtcttagg atcggtaatg tggtctaaga aatattcggt caaaatattt
    10201 tcattagtag ttgaagcaat ttcagccaca aagattggat agtcgccgta aacgtaaggt
    10261 tgagtattgc gagtgtacca ggagtgaacg gagtgaccag tttcgtggac taaagtataa
    10321 agtgaatcga tgttatcttc ccagttgagc aactcataag gatcggtatc ataagcacca
    10381 ccggagtagg caccagttac cttgttttta gattctattg ggtcgatgac acgattatta
    10441 aaaatatagt caacatgctt caagtagtct tcgcccaaag gcttcaatgc ctttttagca
    10501 acttccttag cttcttcaaa gttataagaa agagaaggct tcccagttag cggcacgtac
    10561 atgtcccaca tttgcaaatc ttttaagcct aaaattttct tgcgcaaggc aacgtaacga
    10621 tggagcaggt caaggtgaga atcaacttct tgaattaaag tatcgtaaac tgcttcaggt
    10681 acgccgtttt cagccagtgc tgcttgacgg gcagagtcat atttgtgcgc tttagcgtta
    10741 tagttgtgtt ttttcactac gccggacaag gttgaagcca gcgaattctg gaattggctg
    10801 tacgtagcat agagagtgtc gaaggcacct tttctgacgt cacggttttg cgattgaatt
    10861 aataatgagt acaaaccgtc agatagttgt tccatgttgc catcgtcatc ttggacgtag
    10921 ccgtattcca tgtcagagtt agttaaaacg ttaaaagtat tttcggaaac gcctaaagca
    10981 tctccagcat cagcgattaa cttttcttgt tcagctggca gggtatgagg tcgcttatta
    11041 gtaatcattt ccaagtagtg agcataattc tttagtcttg gctcagcttg cttaaattca
    11101 gctagtttat cactagggat gctcaagatt tctgggttaa taaaactagt agcggcttcg
    11161 aattggttag ctaagctttg cacccggctg acatagccta aataatgtga attggcagta
    11221 tccacatcgc tagacatggt ggcataaaca taaatatttt ccacctcgcg cttaacggcc
    11281 agaatcttag ttaagccttc gtacaaatct ttgccagatt ttgctaatgt accttttaat
    11341 tcaccaagtt ggtcgatttt ttcttgggcc gctgcatagg cctgttccca ttcttcatca
    11401 tttttaaaaa ttcgggtcaa gtcccactta agttcttctg ggacttcatt tctgtttggt
    11461 atcgccatat ttttcctcca taattatttc aatttgtata catcttagcc tgttatgcta
    11521 tctttcgcaa aaaaataagt tattattaat tatcggtatt tttattttat ctagagacga
    11581 aaagtgatac aaataaacta acttgtatta atttcgaagg gaaaagatca aaagaatgga
    11641 ccaaaatcca aaacgaagag aagattatcg tgctcgtcgt tcatcgctta atcttcaccg
    11701 taatcgtgca tttgcggcag acgcgccagc gctgaagcca gggaactttc tggctcggct
    11761 agtgggcgtg gtagctttat tagctgtttg ctttggcgta gcttgggccg cacatatgta
    11821 ctttactgtc cacagtgtga ttgatagcaa gaatggcggt aatactgcta cttccgctaa
    11881 aattgttaat cgacagccaa tttcaatttt agtgttggga gttgaccaag gaattgaagg
    11941 acggcatgat cgaggtaatt cggataccat gattttagcc acggctaatc cgcaaaaaaa
    12001 ctcggcaacg atgacctcaa ttccacgtga caccttagca gatattaaag gcgatccagg
    12061 tgacaaatac tttatgttcc gggtgaactc tgcttatgaa attggcggac atgaatcaag
    12121 tatgaagacg gtctcgtcca tgcttaatgt gccaatcaat tattatcttg aagtaaatat
    12181 gaaggcattg aagagcttgg ttaatgcggt aggcggtgtt gatgtgaatg tgccgtttga
    12241 cttttcatat gactggtgtg atttccacaa gggtaaacag cacttaaatg gccggcatgc
    12301 tgtagcttat gtgcggatga gaaaagaaga tccacgtggt gactatggtc gtcagatgcg
    12361 ccagcgtcaa gtaattgagg caattgccca caaggccatg tcagttaata cgctcagcaa
    12421 ttaccgcaag ctagttgatg tctttaataa gtatgtgaaa actaatttga ccttcaacga
    12481 tatgttaagc ttggcgttga attatcgtgg ctgtatgaaa aatatgaaga gtagctatat
    12541 tcaaggtcat gatgcctgga ttgatggagc ctcaattcaa gttgcttcaa ctaaggaatt
    12601 gcaaaagact tctgatagaa ttcgcaagaa tttgaattta tcgacccaaa cgcttaataa
    12661 cgaggaaaca cggcagaatg agttgaatga tcagaacaat cacattaagt gggatgatcc
    12721 gcaggctttt acaaactatc agatttatga tcaaaatcag gataagccag ccagcggttc
    12781 taattctggt tatggtgaag gaacagggac aggcagctcg tctagttcaa gttcatcatc
    12841 cagttcaagt agcggttggc attttcactg gtaaatgaaa gagtatccga caaggatact
    12901 ttttttctgc ggtaaaataa tcttaagagg tgagaaggat gattggaaca attgtaaata
    12961 cgttagcctt actagtagga acaactattg gctgtttttt gaaaaaagga atcaataaac
    13021 gatttgaaga tgtactcttt attgcaatgg gtttagcagc cttaggtatt ggctgggaga
    13081 atgttactaa taatatgccc aagagtcact atcctgtttt atttattgtt agcttagcac
    13141 ttggtggttt gtgcggcacg gcttgggata tctctggcca ttttgatcgc t
//
