LOCUS       c00109_JAKWZL0..       12190 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAKWZL010000084.1 Lactobacillus crispatus strain
            JKR_P1_15_G02_S687_001-bin_1 NHMMGGNF_84, whole genome shotgun
            sequence.
ACCESSION   JAKWZL010000084
VERSION     JAKWZL010000084
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-20 15:31:26
            Original ID  :: JAKWZL010000084.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12190
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12190
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5813:8348]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5814..8348
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12190
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12190
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(192..1232)
                     /locus_tag="ctg109_1"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKRPA
                     SKSKRVKTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNY
                     EFDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLI
                     DVLRKM"
     CDS             complement(1802..2494)
                     /locus_tag="ctg109_2"
                     /transl_table=11
                     /translation="MTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFPEFISTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(2560..3066)
                     /locus_tag="ctg109_3"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             complement(3032..3142)
                     /locus_tag="ctg109_4"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             complement(3198..3803)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_5"
                     /sec_met_domain="LysR_substrate (E-value: 1.4e-12,
                     bitscore: 37.3, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASRSGYFILNENTARLINTTDL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             complement(3805..3966)
                     /locus_tag="ctg109_6"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             complement(3982..5184)
                     /locus_tag="ctg109_7"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMELKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     ISYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPE
                     QNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRK
                     VAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDY
                     F"
     CDS             complement(5264..5800)
                     /locus_tag="ctg109_8"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDINMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             complement(5814..6716)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_9"
                     /sec_met_domain="OTCace (E-value: 4.6e-47, bitscore: 149.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 2.2e-20, bitscore:
                     63.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLTAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIHKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIIYN"
     CDS             complement(6677..7108)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_10"
                     /sec_met_domain="OTCace_N (E-value: 4.6e-38, bitscore:
                     120.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             complement(7119..8348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_11"
                     /sec_met_domain="Amidinotransf (E-value: 2.1e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             complement(8422..9270)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg109_12"
                     /sec_met_domain="LysR_substrate (E-value: 3.7e-30,
                     bitscore: 94.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.7e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             9399..11672
                     /locus_tag="ctg109_13"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGKVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(11740..12054)
                     /locus_tag="ctg109_14"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVAFLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTSNYRIVDNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
ORIGIN
        1 ttagcttata atttggctta ttgtctagaa cgatttaact agcaccacgc gtatcatcct
       61 ttaatcttac tacacaaaaa taatttttta cacatatttt tttaattttt aagctaaatc
      121 atatttcata aacataaaat aagactagta atcaattcaa attgactact agtctctttg
      181 tttaccaaaa actacatttt tcgcaaaacg tcgatcaata cacgacgtaa gtcttcgttc
      241 ttcttaccca tttcttcgat caatctagct ttatcatcta aagcctgatt atatttatct
      301 tgcaaagcat tatatctttg ctccagttga ttgtaatttc tgattactgt attgtagcgt
      361 tcacgcaaac cgctagcttc atcaaattca taattattcc gattatcata attatttcga
      421 ttattatagc ggcggttaga ctgattatta cgtgagcggt tattattttc tcttctgatc
      481 tcaaaaggat gcttattttg tcgcttacgt tgattttgcg tttgattatt attatttcga
      541 ttattgctat tcttctgatt attcttacgc tcaaagtcct tagattgacc ttcacgactt
      601 tcattctgat ccttagaatg ttgctcaggc ttttctttag tttctgtttc cttattttca
      661 gccgcttttt cagcattctt gcgatacttt tgatcaatct tgatattttg ataaaaagga
      721 ctaagttcag ctataacttt ttcaccatct tcaaccgaaa aacttccccg cttgttaact
      781 ggcttaataa agttggtctt cacaattgaa gcaatcttat cctctaattt cttttgaata
      841 gatttatcaa tcttatcatt ctttataact ttagctaaaa tcttacgctt agtaattgtc
      901 ttaacccgct tagatttaga agctggcctc ttatcagtag catcctcttt agctggggct
      961 tccttagcac gacgttcaat tgcatctgcg taatcttgta cattaccaat aattaattta
     1021 gcaacagccg gcttaaaata ttttcttctt cgcacagtaa tacttggttg tttacgtgta
     1081 cgcacaaagt tataaatttt aatctttagt ttttgttgta attctttact tgcattaggc
     1141 aacaattgat caatcatttg attcattgtt accatttcat ttaaatcaat attttgttgt
     1201 tctaataatg tttgctctac tattcctggc atttccaatc ctatattctt ttaatttttt
     1261 cacaacaaaa agggccatta cggcctattt tgcaataata catcaatttt ctcattaata
     1321 aacttaatgc actttccatt ttacaacatt aacgctattt acgaaaaggg ctacaagcat
     1381 attctctatt ttttaaccaa aacaagcagc atcccatcga tactgcttta ttttatgcgc
     1441 agttgcacta gactttgact ctatttctat tttacgtgct aaccagcctt ttttctagtt
     1501 ttattttctt aactaatcca ttaggtttta catataaatt cttaatatta tttcgctatt
     1561 ataagatcaa ttaagatgaa aggaatgaga accttgatta aactactctt aattggttga
     1621 tcatttttaa cgcttggttt aatggccatc agctcagtat taattaataa accagcagta
     1681 gcaaaggtaa aacatcgcca ctaaaaacca gaataatata tgttaataaa tcttttcccc
     1741 tctaactaga aagaccaggt tatgtactcc acatagcctg gtcttctttt cgtcttattc
     1801 tttatggttg gtagaaaatt gcaccttggt caacaattac atctggttgc aacttacgta
     1861 aactcttact ttcaacacaa tattttgtat tattcaaata ctctttgaag ttcttagttt
     1921 ccaagtgctg cttgtaagct tcattattac gataaacttc aatagctaac cattcatttg
     1981 gttgatcggc aacagttcct gcaatcattg ccaaaatatc tttttcttct tcgactgccg
     2041 ttttcatttc tttcattaca gcatgagcaa actcatcgcc cttacctaaa gaaacaccaa
     2101 tttcagtcag ataaataaca taatcatttg atccggtaac tgctagtttt tctgcctttg
     2161 tagaaataaa ttccggaaac aattctacct ttactcgact agttaaaata tctttagcaa
     2221 cgtcagtaaa atccttaaat tgctttgaat tagcatgagt atcataactt gcttcgtctt
     2281 gatagcattc tactacaaaa ttagtagttt cttcgtcatg acttgtctgc ataaacaatg
     2341 tgcctggttc gttttcttga gaagtaagca tattatgttg ccctgcctta acgaactttg
     2401 catgatcctc tttattagtt tctagtttat ataaacgcaa aattggtgtt tgttttaatt
     2461 tcataacttc tcctccaaga attaattttg tcattattat actaaatttt atcgcgtcta
     2521 ttagtaaaaa acatccctta gttaagggat gtcacaaaac tataacgtgt aattaacttt
     2581 cttaaacttg tagtccttca tttttttagc taatttcttg cttctgaagt agttaccacc
     2641 atcatatcta ctagaataaa ccagcacgtt atgcttttta ccattaatgg tttgtggtac
     2701 cactcgataa agactccaat tttcaaaagt aatccacgga tcaatctcat agaatgtatc
     2761 attcttcatt ttggtagttt taccagacat ccagttttgc gttaccttat caaagttctt
     2821 ctggttagca attctaccat tgaagtaatc actaattgtc gaagcctcct gggtaaatat
     2881 tggtttgcca ttaacagtat gttcagtaaa ggtgatcttt gtgccattat gtgcattacg
     2941 atcataagag taccaagtac cctgcatctt ttttggaata gtaacctgta caccattacc
     3001 ataagttgaa gcatcaacag tctcaacttg actagccaaa ccagttaatc ctaaaacaag
     3061 taccattgat gttaaaggta acaaagttct ttttagcata aaaatcatct ccagaatgta
     3121 aaatatatga gtccgctttc ataatatatt ttacagtatc ttatagtact tagacaagat
     3181 atttttaact ttacagatta atattcttgc tgcaatagct ttataaactc actacttaac
     3241 gctgaatttg acttataaaa agccattatc ttttgcttta ttaactgacc atgatcaagc
     3301 aagaaaagtg gctgcaaatc tgtagtatta attaacctag ccgtattctc atttaaaata
     3361 aaatagccag acctagaggc gaccaacagt gctgcttctt cgaccgagtt agaagcgatg
     3421 aattgactgc caatttgata caaatcttta aataaatgta gctcactaac ctcttcttca
     3481 ggtttagcca caataaaaca agtcatatca ttgagctcgt ctttttcaat catttgaatg
     3541 ccattaggat acattccctt gggcaaaatt gccattacac cagcttgagt caattctgtt
     3601 tcatcaaagt taagattctc gtcacgcaaa tcattgattg ctatgtctgc ttcatcttca
     3661 ttcagttttg caaaagcacc atcatgacta gtcgcaagta gttttacatc tacattagga
     3721 tgttttaaca caaaatgctg cactgcctga tctaattcct tacgacctaa ttggtcaaaa
     3781 tatgcaatct ttaattccgt cattttattt ttcatccagc ggtgcgtgtc cttcttctgc
     3841 tactcttctt ttatccttag tatcttcatg cttattaagt gccatcaagg caaaaaagat
     3901 caaattcaaa ccactaacta caatgccaaa taattttatt aaattgagtt tcttttcttt
     3961 actcattttt taacctcaca actaaaaata atcataaaat gatacatcgc ctttaacgaa
     4021 atctaatttt ttgatgcggt aatctgtaat taatcctagt ttaacagcag cattcatggt
     4081 tagtctacct aatagcacct gggtccacgc ggtaattgat cccgaaaaat caaccaatgc
     4141 atcttcctta cgttctaccg ctaccttacg tccatgatta cttaattgcc aaactccaat
     4201 attccaagga cactgttcat cgctattgac ttccagatta aaatcacctt cttgcattgg
     4261 ccgcatacaa gccaaaactt tttcaaaatc aataattcga ctcatcatat aaggacgcaa
     4321 atcaacttgg agttcgtttt gttcaggaaa aagttcagct cgtaacgatt tctctggtac
     4381 gctcatttta aattgcttaa cactgcccgc gtgcgaaccc ataaaaccaa acatactcaa
     4441 taatccctgc ggcgtaattg cgtacatttc atcagctaaa aaagtattgt ctctaatgcg
     4501 ataaatcaag taactaattg gccgctcatc cgcgtcaaaa taaacggcta cattgcggtg
     4561 atgataataa gaatcaagtc tattccacca ccatgcctca cgtacaaccg tgttacgttc
     4621 atcatcagta tgcagttgac gttcataaag ttgaatcaca ccattttgaa cagctaaatt
     4681 gtcccacttg ccacgcacta tatgaccaga acgtggtaat ttaaaactac gcaatgcgct
     4741 tccatcaaag cgatattctt tttgataaat actattgcta aacccgtact ggcgataaaa
     4801 gctctccgaa aatggtgcca ggttagcaaa cggaatatct tgcctatgta agtcatgcaa
     4861 aatttctttc attaattggg aaatatgacc ttggccacga tactcaggat atgaagctac
     4921 ataacctatt ccagccatcg gtaaatgatg cccaaaaaca tcacttttaa atcgattaac
     4981 cataatatag ctagctaatt tttccttatc aaaatagcca taacctgtac tatgatcata
     5041 acgactcata aaattttcgt ctttagtcaa atcattattt ttcaaaaatg catattgaat
     5101 taatgccgta atttgcttta aattattctt atttttcttt aattccatgc ttattcctat
     5161 acgtacatct ataaatttat tcattactat tttagttcat tttttaaatt tttaactaga
     5221 tttttcataa aaataaaccg gaatcataaa atcccggttt attttacgca acgtattctt
     5281 gataaagctg agagataaat gcctgcatct gttccactga atgtctccgg ctgcgagcac
     5341 attctttagc agggcgatca cataaaaagc acttacgtgg ctgcctgccc aaatctctgc
     5401 gtgaaattgc agcttgttta ttttttacca acacgtctgc atcaaagaga cgtcccaatg
     5461 atatctgatt ctcaaaatca attgttgagc gctttacttt ttcaattgac aaagataata
     5521 cataaaagtt ttcacagcca ctatcatcat taagctgtgt caccaattta aaatgataac
     5581 ctaggttagt ccaagcattt tccagctcat tgatacccaa cataaacatt ttagttaaat
     5641 agcgattatt cttgattggt cctgggatat tcatattaat gtcgactaga gtttgattag
     5701 gatacttatt aaaaatctta tgttgtacag ctactcgcct atctttagct gctaaaactt
     5761 gggcaatatc ctgctttttt ccttcattaa aaatattcat ttttatcacc cagttaatta
     5821 taaatgattg tgccgactcc gtctgctagt ttgttggcat tgctcaaaga ggtgataatt
     5881 gctaaattac ctgttttttc tacaaattca attgcagctt ctatcttagg cttcatactc
     5941 ccagctgcga aataacctgc tgctagatat tgtttgagct gttcaacttt tattttacca
     6001 attgcttgtt gattttcttt gccataattc aaaaatgcat gatccaccgt tgttagaatt
     6061 actaattcat cagcgttgat atcttctgcc attttagcag cggaaaaatc tttatgaatt
     6121 acgccggcaa cacctctgag atgcccatct ttcacaataa caaggatgcc accaccgcca
     6181 caggcaatcg gaataaataa atttcctaaa gtagccgcca tcactgcttt aattgaatgc
     6241 aatcgatttt cagcttctgt aaattgccaa gcatactttg aattaaagac ctcatcagtt
     6301 acttccatct catttaagcc atatttttca tagatttctt ctcccacctg agttgttcga
     6361 tcatgaaaag ctgtcaaaca atgcataaag atcaattggt catctggtgt accagtcatt
     6421 tgcatcattt tcattgtgac cgtatatggc tttaataatt taattcgttc agaccaatca
     6481 ttttcaccca tcgaaaccca aacatcggta taaacaacat tggctccttt aacgccttga
     6541 gcaatatcat ctgtgatcaa attttttgaa cctgaatctt gggcaaaatt ttgagcaatt
     6601 ttttgtacat caggatgtgt aaacaaaggc ttgggtgtaa caatatgtac attaacacct
     6661 aacattgagc cacaaactaa aagactgtcg gcaacattat cgcggccatc acccacttcc
     6721 aaacaggaac gccagaatat ttagccagct cttctacatc ttcttgagca aaaccgcgat
     6781 attcaattcc atcatacatt gagcctagga ctttagccgt atccttgacg ctttcttttt
     6841 tacctaagtg gatctcgctt gcgcctagat attctggatg agcacctaaa tcattacaag
     6901 ctactacaaa agcagatcgc gtcctagttg aggctttttc aaaaagtagt gcaatatttt
     6961 tacctttcag atattcatgt gggatatgct cttttttaag ttcttttaaa tgtaatgcaa
     7021 aatcaattaa atatgaaatt tcagctggag tatagtcttt acaatcgaga aaacttctac
     7081 cttgaaaaac attttgtaaa tatttcattt tttgcctctt ataaatcttc acgaatcaac
     7141 ggacacgaca tacatctagg accgccacga ccacgtgaga gttcactaga ccgaatctca
     7201 tgaacgatga tgccatgttt tcttagcaaa tcattggata cataattacg atcataagta
     7261 acgacttcac ctggtgcaat tgccaaggta tttgagccgt cattccattg ttcacgtggt
     7321 gcggcaattg gatcaccacc accagttgga attaaatcca attcgcttaa atgtaagttt
     7381 tctttcaaaa cctgcaccaa atcattcttt tctgtgattt ttacaccgtt gtgatcatcg
     7441 ggctgtagaa cataaatatc aattttgccg gctttatcta aaataaaggg atgaaccgta
     7501 aattgattat aattaatcat tgtaaaaact gtatcaaggt gcatcatagc atgattgtgc
     7561 ggaatcttaa tcgctaaaat cgtatcataa cttgaatgat caaataaatt atgagctaag
     7621 tcagtaattg cagttgcaga agtgcgttgt gaaataccta cagctaacac atggttattt
     7681 agaactagtt catccccgcc ctcaaggcga ccatgatgat aacggtcacg ccaaactgga
     7741 atagttgcgt tcttgaaatc aggatgattt ttcaaaattg tttccataaa taatgattca
     7801 cgtcgtctag ctctgaaagt catccggtta atggtcatcc ctgaaccaat tgcagcctgt
     7861 tgatctcgag taaaatatac atttggcatt ggatcaagat aaaaagggta atctgggtcc
     7921 tcagccaaat ctgctaaaga tggggtagaa ttatgaatcg cactttttct aattccagca
     7981 atcaccgttt ttaccatttc cttagttagc aattcttgga gatagttcag caataattga
     8041 tgcaaaggat cctgtttttt aatacttgat tcatccagta actgatctaa gaatgcccga
     8101 cgaactttct catctgttaa agattctgct aataaatcct caagatataa tactttgatc
     8161 ccctgctgcc tcaatacatg cgcaaaagca tcatgttctt cttgggcaat cttcagataa
     8221 ggaatatcgt caatcaacat tcgatgcaaa atatctgggg ctagattttc tagttctttt
     8281 cccggtcgat gtaacatcac cgtttttaac ttaccaattt ctgaataaac atgaatcgga
     8341 ctcgacattc aaccaccttc tattaattat tgtacccgtt tacatttatt atggatcaat
     8401 taggtaaaag ttacagtatt atcatattgc agcaatgatt tttttcatta aaggtgtaac
     8461 ttgatgatct ttacgccaaa ccagctgcaa atgtgttatc caattagcat gtttaattgc
     8521 gatcatattt tcttgggcat aagttgtcgc aattgattct ggtactagcg ctactcccat
     8581 ttttctcttg gcccaagtaa ttgctgtccg tgaatcatca cacttaaccg cataaaatgg
     8641 tttaagccca tgatgtgcaa aagtttgatt aaaaatatcc tcaaagcgac gataaataat
     8701 caatggctga tctgctagat ctttaatgcg taattctttt ttttgctgaa aatctgggtc
     8761 tacactaata gccatcattt tttcagttgt taaagtctta gtatttaaac ctgtctggtt
     8821 gtaaggcgtt cgtacaatgc ctagatcgat tgtctttttt tctaatttat ccaggatgcc
     8881 ataagtatta tcttcataaa tatcaaaaga aatttccgga taatattttc gtaattcatt
     8941 aaaagaattc attggtatca agcccgttga ggaagatgcc attccaattg caatcgttcc
     9001 caattcaccg gaaatagtct tatgtacttg gttttcagca ttttgagcta gagaaataat
     9061 ttcattggca tagctttgaa aaatttgtcc cacatcagtt agctcaatac catgtgccgt
     9121 tcttttaaat aattgcgcgc ccaactcttt ctctaattgt tttaattgat agcttaatgg
     9181 tggctgtgca atatacaagc gcttagcagc tgctgtaatc tgcttttctt ctgctacaac
     9241 tagaaaataa cgtaactgtt ttagattcat attatttatc ctttttttat ttcaattgat
     9301 agtgatatta aaatatttaa tatcttatat tgtattttag tattttattc atagcaatat
     9361 ctgtgctacc ttattaaggt agatttggag ggaaaataat gtctgataaa tttcacggct
     9421 taactcaagc cgaagcagac aagcgcttaa aagaagatgg cttaaatgaa gtaccagagc
     9481 ctgaatacaa tttctttaaa gagttcttgt ctaagttatg gaacctatcc gcttggattc
     9541 tagaagctgc tttaattcta gaatgtatct tgggcaaatg ggtccaatca ttattcgtgt
     9601 tgttgatgct tttatttgct gcatttaacg gtgcatctaa gaaaaagcaa tcaagacgag
     9661 ttttaaataa tatttcacac aagttgactc ctactgtatc agttgaacga gatggcaagt
     9721 ggatcaaact tgattctaaa caactagtta aaggcgattt aatctcactt aaacgcgggg
     9781 acgtactcgc agcagatgtt aaaattgttg acggtaactt agcttgtgat gaaagctcaa
     9841 ttacaggtga atctaaacca gttaagaaag caattgatga caccgccttt gccggtacta
     9901 cagttgttga aggtgatggc ctagctgttg ttactgctac aggtaaagat tctagaagcg
     9961 gtaagacgat taatttgatc aacaattccg ctgctcctgg tcacttacaa caacttttga
    10021 ctaagattat ctactacctt tgcttactag atggtgtttt aaccttagtt attattatcg
    10081 cctccttctt caaaggcggt aatttcaata cctttattaa tatgttgcca ttcctggcaa
    10141 tgatgtttat tgcttcaatt cctgtagcaa tgccatcaac ttttgcttta tccaactcat
    10201 ttgaagcaac ccgcttaagt aaagaaggag tcctgacttc tgacctaact ggaattcagg
    10261 acgcagctaa cttgaacttg cttttacttg ataagactgg aacaattacg gaaaacaaaa
    10321 ctgccgtagc cgcttggact gatctaagtg acttgcctga caaagacgtg cttgctttag
    10381 ctggagccgc aactgataaa cgtaatgctg gtattatcga tacagcaatc gatgaatact
    10441 tagtagaaaa taacattcca gtcatgaatg ctgaaaactt tactccattt acttctgaca
    10501 ctggttattc tatggctgat gttgctggac ataatgtaaa gcttggttca tttaagcaat
    10561 tatctttgat cgataaacat gccgatgaag aaatttctgg aattaatttc aaggcaggac
    10621 gctcagtggc agtcttgatt gacgataagt tagctggtgt cttcatctta caagataaag
    10681 ttagaacaga ctctaaagca gctttggctg aactcaagaa acgtggcgtt cgcccaatta
    10741 tgttaactgg tgacaatcaa aagaccgctg ctgcagtggc agaacaagtt gatttaactg
    10801 gtaaagtaat ttcgattcac gatttcaatg aaaatactga tattaatgat ttggccggta
    10861 ttgctgatgt tttaccagaa gataaactca agatggtaaa gcttttccaa gaaaaaggct
    10921 atatcgtagg gatgacaggt gacggagtta acgacgcgcc tgcattaaaa caagctgaag
    10981 taggaatcgc agtttcaaat gctgctgacg tagctaagcg ttcgggtaaa atggtattac
    11041 tagacgatgg tctaggctca attgttaaaa ttttagacgc tggacatcgc gtataccaaa
    11101 gaatgactac ttggtcacta accaagcttg ctagaactgc tgaattaacg atgctgttaa
    11161 cttttggcta tcttttcttt gactacatcc caatggcctt gaatgcaatg gttatctata
    11221 ccattatgaa caatatggtt acgatgatga ttggaactga caggactcac attacttata
    11281 agccagaaaa ctggaatatg gctaagcttg ctaagatcgc cttttcacta gctgctggtt
    11341 ggactttaat tggtattggg tttgtttggt tcttaaacac acacggttgg agtcacggtg
    11401 ctgtttctac tatggtttac gtatacctag ttcttagcgc aatgttgatt gttttgatta
    11461 ctagaactcg taagtacttt tggcaagatt acccatccaa gttggttggt agtgttcaaa
    11521 ttgcagatgt tctattgacc tttatcttag ctctttgtgg ttgggcaatg gtccagattt
    11581 ccattcaaaa cttagcaatt actgtaattg tagcgattat tgctgccata ataatcgact
    11641 taatttacca acctgtgatg aaaaacaggt agattattac cataaatttt ataaattaaa
    11701 agacttctag gaactttgaa ctcttagaag tcttttaatt tatctttttg attcacgata
    11761 tcctgctgca cgtgctgctg ctttactctt gaagaaaact gcattttcac gattcattcg
    11821 ataattatga ccgcgcatta cgtgaaagat ttttgatcgt ttattatcaa caattctgta
    11881 attactggta taaatcttag ttttatcacg atattgatgc tttctccttc tgtgatgaat
    11941 agctgcatta acaactgatg tcgacccctg caaatttgca ggcagaacac tgatttctcc
    12001 cactaacatc agaaatgcaa caatagtcac aacccaattc ttgcatcttt tcataaaaac
    12061 actcccttaa tatgtcacta tatttatata gtatacgttt atatatgaag tgttcctacg
    12121 tttattagaa actagtttga aactgtcaaa tcttttgtgt aaatagttct ttctcgtaaa
    12181 ttgatttttt
//
