LOCUS       c00162_JAKXAD0..       13587 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAKXAD010000244.1 Lactobacillus crispatus strain CM_B12_S858-bin_1
            KJCBDHIP_244, whole genome shotgun sequence.
ACCESSION   JAKXAD010000244
VERSION     JAKXAD010000244
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 18:23:54
            Original ID  :: JAKXAD010000244.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13587
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13587
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3176:8587]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3177..8587
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13587
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13587
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             2..118
                     /locus_tag="ctg162_1"
                     /transl_table=11
                     /translation="DLHSVNRRQRQMCIRDSSTVGIKCDKPDLIHDAHLLSF"
     CDS             complement(87..983)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168.6; E-value:
                     3e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg162_2"
                     /transl_table=11
                     /translation="MLKIEHLNKSFGSTQVLFDVSFSVSDGRILGLVGKNGSGKSTIFH
                     SILKFVDYDGQISIDGHSFNAKDYDNIGYLPEERSLMPKLTISDQVVFLASLKGMPAKK
                     VKEELPDWLSRLAVKGIPMDKIKSLSKGNQQKVQMIATLIHQPKLIILDEPFSGLDPVN
                     VDLMKQLILEEKRKGATIIFSDHDMRNVEELCDDVVMINDGHIVLNGPVNEIKNSFGLT
                     RIFVRTDKSATELSALPGVKDIILQNNGMKLLILADEKYGKDIFNQLSAGQYIQTFDQE
                     PPTLDEIFKMKAGARHE"
     CDS             complement(1001..1423)
                     /locus_tag="ctg162_3"
                     /transl_table=11
                     /translation="MNNEKFARENKRIIEGMGIGALVGPILALVMMYVKTAGSPQPFQI
                     IMSIGAGLAFGLMFGGIMSASLVLNKTVASKIPWQKKVLKLAPQVIGTGVVVASAGVVI
                     TLVTNWGSVDIVKTIFSTDTLWQFFDGVLLGLITIR"
     CDS             complement(1450..1641)
                     /locus_tag="ctg162_4"
                     /transl_table=11
                     /translation="MLYLIYIVLGLLIILAVNYAVTAFLAVHDLLENREKDQLSFGDAF
                     KKYFAKNNIPTKFSDLFN"
     CDS             complement(1998..2537)
                     /locus_tag="ctg162_5"
                     /transl_table=11
                     /translation="MKKLILNLLTIFAWIYQIFCVIGIIMWIVMGGVVLFGIHNPDFRA
                     GFESGRGIKGVSVDNYIGAIVVVLLSLIMMSVAAFLICRYARLIVKNIKQEVYFADSNL
                     NLLKKLLISVAGYTLISIIDYIIFITHRTWFAKSSNNVLYPSGVTTGLLFLAVLYVVYL
                     VFKYGMKVQEDADSII"
     CDS             complement(2542..2724)
                     /locus_tag="ctg162_6"
                     /transl_table=11
                     /translation="MLPEKKRQIGSIIGMLIMMAILVFANLGGTWSVLRITLLVIGVTG
                     VIGSAIYRIIHILRG"
     CDS             complement(2892..3107)
                     /locus_tag="ctg162_7"
                     /transl_table=11
                     /translation="MKNKILTERQVRNRSIIAGILALLIGLVWDYFQYKTLSFGTVFWN
                     IVESVAFVIFMNIFMNSYYKKKSKKQ"
     CDS             complement(3177..3371)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg162_8"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 6.7e-09,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKEMNYKELEKVSGGTNWLGVGGSCLSGFIDALPSGSGMIKGCV
                     EGAVKDFAKQNRHKKHKHR"
     CDS             complement(3389..3640)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg162_9"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.8e-15,
                     bitscore: 48.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKFETLTYEELSAVFGGNGGKARRRRKITNCAKAIGMGALKDGL
                     KYGIAGTAFGTPIGTVGGAIFGANVGIISGSVSCVSHL"
     CDS             complement(4233..4430)
                     /locus_tag="ctg162_10"
                     /transl_table=11
                     /translation="MKRIIISKDEVLLSGILGGSGSVDDIGLTDTEHMLPLYSKKGGNH
                     KRDVYLENPKFFQSSFHRGR"
     CDS             complement(4431..5735)
                     /locus_tag="ctg162_11"
                     /transl_table=11
                     /translation="MNKKKILMLMLSPAVLLMMNSTIVHADEGNTSQENKSEVVSKTEN
                     DDKNVSESEQKTSSKNEAAQTQNKQEEEPAASEDQNNQSQNTNNQDPNNANEEDSEDDE
                     DEVSVEDYENNVKDFHRVKMQEVKDLLAEKNNQEHLMYIGRPTCYYCRQFSPDLKDFNE
                     IVKGKLLYFNIDAEEGAHEYAFKEIGIPGTPTTMRFINGKIISAWVGGEKTGQELYNFL
                     YSDAANKLVEQAVIKDQPKDDNTTESESNEIPEVTVAEDDQTQSSNDVAITDFVENSVF
                     ENAANVASSTADLTKVTTGNQEYAAPRAETKKKTVKKPVKPKIVATKVKKTAKSHKKNI
                     ILAAVSEKHGSVKENKQFDSVKVQSKPYSAVKNNQNRITKLKRLENDTIKNGSTQSLPS
                     TGEKDNIWGQLIGMISILISLVLGISLGKKTKEEK"
     CDS             complement(5890..6486)
                     /locus_tag="ctg162_12"
                     /transl_table=11
                     /translation="MNNKDYESTEYYSYKFKNFSTMIIIPMAILVLILIVGSFFATRQS
                     TVTSTGIVEPQNTLNIANRNYHEGQIVRRNREKWLVHLDDKQENTVHLFPMIKAKRTVN
                     VVTYFPGNKIGAIKKGQTLYFQVANASGTMDRLVGKVKEIGVYPINLRGNNVYEVICKA
                     KSKKNLKYGMEGNATIITGKSTYFEYFKDKILNQN"
     CDS             complement(6497..8587)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 311.6; E-value:
                     1.8e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg162_13"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1038.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.4e-35, bitscore:
                     110.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILKKYHSRVFLAHLRHSARTNLEGTTALGLVKTAQAFNLKTEAV
                     KADMSLFDPDADIQYPFIVHVLKQGELLHYYVVIKATKNYLVIADPDPSVGLTKMSKEK
                     FSQEWTGIALFMVPNDDFEPLKEKKQNLWSLFPYMFKQKKLVTNIILAALLMTIISICS
                     SYFLQGLIDTYIPSGTYQTLSILAIGLLIAYVFNSIFSYGQNFLLDVLGQRLSIDLNLQ
                     YIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGIVLAIQ
                     NSTLFVITLLSLPIYAVVILSFSKKFEKMNNDQMESNAVLSSSVIEDIQGIETIKALNS
                     EQTRYRKIDSQFVDYLKKSFRYSKTESLQSALKTFIQLSLNVIILWVGAKVVMNGQMSI
                     GQLMTFNALLSYFVDPLQSIINLQPTLQSANVAQNRLNEVYMVKSEFQKDAQIRDAKQL
                     AGEIEYHHVDYHYGYGVDVLKDINLKIEPNDKLAIVGMSGSGKSTMVKLLVDFFSPSKG
                     KLTFNGFNSTKVDKHVLRSYVNYVPQTPYIFSGTIKENLLLGSRPDITEKDILKACQIA
                     EIESEIEQLPLQFETKMDENAKILSGGQKQRLTIARALLSPAKILIFDEATSGLDTITE
                     KKVVDNLMKLKDKTIIFIAHRLAIAQRTNNILVVDHGQIVEQGSHEKLMQKHGFYYNLV
                     EN"
     CDS             complement(8783..9583)
                     /locus_tag="ctg162_14"
                     /transl_table=11
                     /translation="MSKFPIIVCDDDKDLANQMAKNINASIQDLIDDNEGYAELNESVT
                     FVANDFAQAVGYIVTNDIKNGIYFLDIELSRESKAKNGVDLAEFIKKNDENAQIIFVTA
                     YDKYAPLTYRRRIGAIDYISKSMSSDKIIQRIEETLRNAFDNLSNRIKFSQRDFTYKIG
                     RRVCKVAEGDILFIEHSTTQHKVHMVTENGEVEYKANITQIDKENPFLAKVSQSSLVNP
                     KNISAIDTKERIIIFDNGQMVTYSRSYKAVVKKLVDKFENIKVE"
     CDS             complement(9576..10904)
                     /locus_tag="ctg162_15"
                     /transl_table=11
                     /translation="MEKIVLFLFLNVFSSLADVWCFFKISRVRSKKRQILFLCIANIFL
                     GLLLSIGNIGVIFTNILETLLFVLYLRKNNTLEILFGSIILVCTLDLLVDIVSDMITQV
                     MSFTLIGQLSLRFLLILMMIVAIKLGNGKIYNYLANQNNKIFVGILAYTYVSTVSISII
                     YIQSKSFTPLTLFFSLYILIQTIFAIFIYHEMTMVQEKLLNKKDQEKLKQQQHQLEEYA
                     SYLEKSEDDLRAFRHDYKNILNSLKVSAQEGNVQEVIQKLDKYTETNLNSKALLKYKDL
                     NHIYVKSIKSIIIPKITELYNLDIPYNFECRNNIRNLPDHVDELDLVRIIGITFDNAIE
                     ESKALIAEKHDIRSAEVQIMVYSDDPDEFEFEIRNKIQNKNISTSQIQQRGFTTKKDHK
                     GLGLANIKEIESKYPDMSISYTIQDGWFDFYMTIDTEDGEEDE"
     CDS             complement(10892..11023)
                     /locus_tag="ctg162_16"
                     /transl_table=11
                     /translation="MKKQNVKKTVLKEEELTKVVGGSTAHVGFNFLSKKLWNNIWKR"
     CDS             complement(11141..12538)
                     /locus_tag="ctg162_17"
                     /transl_table=11
                     /translation="MFVGRHQELEQLNQAYQENDFQFTVIYGRRRIGKTSLINEFLKDK
                     KSIYYVALEENAEDNLKRFSDAISIFKNTDQGGKEKFANFEECFKEITHLAQKQRVILV
                     IDEFPYLAKAYPTISSMLQSYIDHEFKETNLFLILCGSSMSFMERQVLGYQSPLYGRRT
                     LALKLEPFKLSEAHEMLPKLSKEDAFIINTVCGGVPQYLSYMSDSMSVADNIKKNFLSK
                     SGRLFDEPNNLLQQELRDPTNYNSIINAIASGASKHSKIAQSAHLQTGPLTTYLNNLID
                     LGIVEKKLPVTEQKKSKSKNIVYRICDGMFRFWYTFVGKQTDLIERGLTDLAWVKVQKG
                     LSDFMGPEFEKYSQDFMWSQDMNEKIVPNPFIHLGNWWGTDKRTHQQVELDIVGFSDDE
                     RDGYFGECKWKNEPISRSVLEKLITNSEIFKYPLKHYYLFSKSGFTDSCQELAKKINCQ
                     LFTFEEI"
ORIGIN
        1 agatctacac tcggttaatc gtcggcagcg tcagatgtgt ataagagaca gctctacggt
       61 aggaatcaaa tgcgacaagc cagatcttat tcatgacgcg cacctgcttt cattttgaaa
      121 atctcgtcta aagttggagg ttcctggtca aaagtctgga tatattgacc ggccgaaagt
      181 tggttaaaaa tatccttacc atatttttcg tctgcaagaa taagcagctt cattccattg
      241 ttttgcaaaa ttatatcttt tacacctggt aaggctgata attcagtagc acttttgtct
      301 gtcctgacaa aaattcgagt taggccaaag ctgttcttaa tttcatttac tgggccattc
      361 aagacgatat gcccatcatt gatcattacg acgtcatcgc acaattcttc cacgttacgc
      421 atatcatgat cagaaaaaat gatcgtagcg ccttttcttt tttcttccaa aatcagctgc
      481 ttcattagat caacattaac aggatctagt ccactgaatg gttcatctaa aataatcaat
      541 ttaggttgat gaattaaagt tgcaatcatc tgtacttttt gttggttacc tttagacaaa
      601 gacttaatct tatccatggg gatcccttta acagccaaac gtgataacca atcaggcaat
      661 tcttctttta cctttttagc cggcatccct ttaaggctag ccaaaaacac tacctgatct
      721 gaaatagtta acttaggcat caaacttcgc tcttcaggca gatagccaat attgtcataa
      781 tctttagcgt tgaaagaatg tccatcaata ctaatctggc cgtcataatc aacgaatttc
      841 aaaatactat gaaagatcgt cgacttaccc gacccatttt taccaaccag tccaagaata
      901 cgcccatctg acacactgaa gctaacatca aacaaaacct gtgttgaccc gaagctttta
      961 tttaggtgtt ctatttttaa cataattttt cctcaacttt ttatctaatg gttattagac
     1021 ctagaagtac accgtcaaag aactgccata aagtatcggt tgaaaaaatt gtttttacaa
     1081 tatcaactga cccccaattg gttactaaag taatcactac accagctgaa gcaaccacta
     1141 ctcctgtacc aataacttga ggggcaagtt tcaacacttt cttctgccat ggaatctttg
     1201 atgcgaccgt tttattaagg actaagcttg cggacatgat gccaccaaac attagaccga
     1261 aagccaatcc ggctccaatc gacataataa tttgaaaagg ttgaggcgaa ccagcagtct
     1321 taacatacat catcacaaga gctaatattg gtccaacaag tgctccaatt cccatgcctt
     1381 caataattcg tttgttttca cgagcaaatt tttcattatt cattgttctt acctcaagga
     1441 aattttcagc taattaaaca aatccgaaaa cttagtcgga atgttgttct tggcgaagta
     1501 tttcttgaat gcatccccaa aactcaattg atctttttct ctattttcaa gcaaatcatg
     1561 aacagctaag aatgctgtaa cggcgtaatt aacggctaaa atgattaaca aaccgagcac
     1621 aatataaatt aagtacagca ttgttctttc ctccaattca gcgattatct cccaggaaat
     1681 aatcttttat ccttttaaat taatcatatc cccatcattt atgtaaaagg taaaaccgtc
     1741 caattctgtc atttttcgga ctgattttgc attttattct tcatcttttt tataaactaa
     1801 taaatcccct ggttgacaat ccaagacttc acagatcttg ctcaacgtgt cgaagcgaac
     1861 gccatgcgcc tttcctgtct tcagaatcga caggttagcc ggcgttatac caactttctc
     1921 tgccaactcc tttgaagaca tctttcgctt caagagcata aaatctagtg tcacttcaat
     1981 catctatatc aacctttcta aataatcgag tctgcatcct cctgaacctt cattccgtac
     2041 ttgaatacca agtagactac gtatagtact gctaggaaaa gcaaaccagt tgtcacacca
     2101 cttgggtata gtacattatt cgaggattta gcgaaccaag tgcggtgagt tatgaaaata
     2161 atgtaatcta ttattgaaat aagggtatat ccagcaactg aaattaataa tttcttgagt
     2221 aaattcaaat tactatcagc aaagtaaact tcttgcttga tattcttaac aattaatctg
     2281 gcatatcgac agattaaaaa ggctgcaacg ctcatcatga tcagtgatag caacacaacc
     2341 actattgcac cgatatagtt atcaactgat acgcctttta tacccctacc actttcaaag
     2401 ccagcacgaa aatccggatt atgtatacca aataacacaa cacctcccat aacgatccac
     2461 ataattattc ctatcacaca aaatatttgg taaatccaag caaaaatcgt aagcaaattc
     2521 aaaattaatt ttttcatttt tctatcctct caaaatatgg atgattctgt atatagcact
     2581 gccaattaca cccgttactc caattactaa taatgtaatt ctaagaacac tccatgttcc
     2641 gcctaagtta gcaaacacta agattgccat cattatcagc attccaataa ttgaacctat
     2701 ctgtcttttc ttttctggaa gcatatctat ccctctcttc cataaaacta tctatctctt
     2761 tctcgtcttt tataattatt gtattacgat aatttataat tgcaatacag aaataaaata
     2821 tttttttggg ataataaaaa aataccaaat tagtcgttaa actaacttgg tattatgttt
     2881 tatcttccaa gctactgctt tttacttttc ttcttatagt aagagttcat gaaaatattc
     2941 ataaagataa caaaggctac actttcaact atattccaaa atactgttcc aaagcttaat
     3001 gttttgtact gaaaatagtc ccataccaat cctattaaca gggccaaaat accagcgatg
     3061 atacttctgt ttctaacttg gcgctcggtt aaaattttat ttttcataat ttttacccca
     3121 ttattatcat atcgaaaaat aggaaatcta ttaaccgaat tttctatttt ttaatattat
     3181 ctatgtttat gttttttatg tctattttgt ttggcgaaat ctttaacagc gccttctaca
     3241 catcctttta tcataccact tccgctaggg agcgcatcaa tgaaacccga taaacatgat
     3301 ccacctacac caagccagtt agtgccacca cttacttttt ctaattcttt ataattcatt
     3361 tctttcatca taaaagttac ctcctttttt acaaatgtga tacacaagaa actgatccgc
     3421 taataatacc cacattagca ccaaatatag ctccacctac tgtaccaatt ggagtaccaa
     3481 atgcagtgcc tgcaatgcca tattttagtc catccttcaa cgctcccatt ccaatagctt
     3541 tagcacaatt tgtgattttt ctacggcgtc ttgctttacc accgttacca ccgaaaacag
     3601 ctgacagttc ttcataagtt aaagtttcaa atttgttcat gtttttcccc tttataaaac
     3661 ttctaattac aattttcata agtgaattaa gttttacctc tcttcaactt acacactaat
     3721 aatacaaaac aatttacctt cattggcgta taataccgat ttagcacgaa acaagatcta
     3781 tttggaaaat atttaccaaa tcggccaagt tttcgtatat tagtaattta caaaggattc
     3841 ttattaattg ttacgctaac ttgatattct gttttataaa tccgaaaact agtaaaaaca
     3901 tagacacaat gcacttatta tgagaatggc taacaaaaaa atcttctcat agccaaggct
     3961 acaagaagat tgccatcaca ttaatgcata aactgatacg cacgctcttt actttaataa
     4021 aacatgatca attatacgac tataacatag ccactcaaaa cccaaaactt gagtcgaaat
     4081 caaataatca tttttagcat agtaacctac gaaaaaaatc acaagtttca taggtttctt
     4141 tgcgttatct tctaagtatt acgatatttt ctattggaga tatttttagc ctattcgcac
     4201 cagtattttt ttcaatactt atctactagt tattatctac ctctatgaaa agaactttgg
     4261 aaaaacttag gattttccaa ataaacgtct cgtttatgat taccaccttt cttactgtat
     4321 aaaggtagca tgtgttcagt atcagttaga ccaatatcat ctacagaacc tgacccacct
     4381 aaaattccgc ttaaaagtac ttcatcttta gaaataatga ttcgtttcat ctacttttcc
     4441 tccttagttt tctttcctaa tgaaatgccc aaaactaaac tgattaagat actaatcatt
     4501 ccaattaatt gaccccagat attatccttc tcacctgtag atggtaaaga ctgagtagaa
     4561 ccatttttaa tagtgtcatt ttccaatcgc tttaacttag taattctatt ttgattgttc
     4621 ttaacggcac tataaggctt gctttgcact tttactgaat caaattgttt attttctttc
     4681 acacttccgt gtttttcact aactgctgct agaataatat tctttttatg cgatttagct
     4741 gttttcttga ccttagtggc tacgatttta ggttttactg gcttcttcac agttttcttc
     4801 ttagtttcag ctctaggagc cgcatactct tgattacctg tcgtaacttt agtcagatct
     4861 gcagtagagc tagcaacatt tgcagcattc tcaaatacgc tattttcaac aaagtcagta
     4921 atagcaacgt cattgctaga ctgtgtttga tcatcttcag ctacagtcac ttcaggtatt
     4981 tcattacttt cagattcagt agtattatca tccttcggtt gatccttaat tactgcctgt
     5041 tccactaatt tattagctgc atcagaatac aaaaagttat ataactcttg tcccgtcttt
     5101 tctccaccga cccatgcact aataattttt ccattaataa atctcattgt agttggagta
     5161 cctggaatac caatttcttt gaaggcatac tcatgtgctc cttcttcagc atcaatattg
     5221 aaataaagca gcttaccttt aacgatttca ttgaaatctt ttaaatcagg tgaaaattgt
     5281 cgacagtagt aacatgttgg acgaccgata tacataagat gttcttgatt atttttctct
     5341 gctagaagat cttttacttc ttgcattttt actctatgaa aatcttttac attgttctca
     5401 taatcttcaa cagatacctc atcttcatca tcttcactat cttcctcatt tgcattatta
     5461 ggatcttgat tattagtatt ctgtgactga ttattttgat cttcagaagc tgctggctct
     5521 tcttcctgct tattttgagt ttgagctgct tcgttcttac tactagtttt ctgctcagat
     5581 tcggaaacat ttttatcatc attttctgtt ttagatacta cttcactttt attctcttga
     5641 gaagtattac cttcatccgc atgcacaata gtactattca tcatcaataa tactgctggg
     5701 ctcaacatta acattaatat ttttttctta ttcatagatc ttcctccgta ttttttataa
     5761 ctaagaaaaa tatatcaatt atcagctatc tttttggtta tcagacttat tcagtacact
     5821 ttttgaccaa atcagttatc aaaataattg gaatttgatt ctaactaaaa aagagctttt
     5881 cagctccttt taattttggt taagaatttt atccttaaaa tattcaaaat atgtactctt
     5941 acctgtaata atagttgcgt tgccttccat cccatatttc aaatttttct tggacttggc
     6001 cttacagatt acttcataga cattatttcc gcgtagatta atgggatata ctccaatttc
     6061 tttcactttt cctactaatc tatccattgt tccactagca ttagctacct gaaaatacag
     6121 tgtttggcct ttttttattg ccccaatttt attacctggg aaataagtaa ctacattgac
     6181 cgttctttta gccttaatca tcggaaacaa gtgaactgta ttctcctgtt tatcatcaag
     6241 atgaactagc catttttctc tatttcttct aacaatttgt ccttcatgat agtttctatt
     6301 ggcaatatta agtgtatttt gtggttctac aattccggta gatgtaactg tactttgtct
     6361 agttgcaaag aaagaaccga ctattaagat cagaactaaa attgccatag gaataataat
     6421 catagttgaa aaattcttga atttatagga atagtattcg gtactctcat agtctttatt
     6481 attcataacg ttgctcctaa ttctcaacta agttatagta aaagccatgt ttctgcatta
     6541 atttctcatg acttccttgc tcaacaattt gaccatgatc tacaaccaga atattgttag
     6601 tcctttgtgc aattgctaaa cgatgagcaa taaaaataat agttttatct tttaatttca
     6661 ttaaattatc tactactttt ttctctgtaa tcgtatcaag cccgctagtg gcttcatcaa
     6721 aaattaaaat tttagccggt gacaataatg cacgtgcaat agttagcctt tgcttttgcc
     6781 caccggataa aatcttggca ttttcatcca tcttggtttc aaactgcagt ggtaattgtt
     6841 cgatttcaga ctcaatttct gctatctgac aggctttcaa tatatctttt tctgtaatat
     6901 ctggtcgact acctaagagc agattttctt tgattgttcc tgagaagatg tatggtgttt
     6961 ggggaacata gtttacgtat gaccgtaaga catgcttatc tactttagta gaattaaatc
     7021 cattaaaagt taacttgcct ttgcttggag agaagaaatc aactaaaagt ttgaccatag
     7081 tagacttacc tgagccactc atccctacga ttgccaactt atcattgggt tcgattttta
     7141 aattaatatc ttttaataca tcgactccat agccataatg atagtcaaca tgatgatatt
     7201 caatctcacc tgctaattgc ttggcatccc taatctgagc atctttctgg aactcactct
     7261 taaccatgta tacttcattc aatcgatttt gtgctacatt agctgattgt agagttggtt
     7321 gaagattaat aatgctctga agtggatcta caaaatacga tagtaatgcg ttgaaggtca
     7381 ttaattgacc aatgctcatc tgcccgttca ttacaacctt agcccctacc cagaggataa
     7441 ttacattgag agataactga atgaaggtct ttaaagctga ctgcaaagat tcagttttac
     7501 tgtaacgaaa agatttcttg aggtaatcga cgaattgact atcaatctta cgataacgtg
     7561 tttgttcgct atttaaagct ttgattgttt caattccttg aatatcttca attactgaag
     7621 aacttaagac agcattactc tccatctgat cattattcat cttttcaaat ttcttagaaa
     7681 agctaagaat caccactgca taaattggca aagacagtag agtaatcaca aatagagtgg
     7741 aattttgaat tgccaaaact attcccatca caattacaat tgaaagatca agaaataatg
     7801 aaataactgt actggcgagt gcgtcaataa ttcgactagc atcagagaac cttgaggtaa
     7861 tttcccctgt tctacgagtt acgaagaatt ccattggtaa ttcaaaaata tggcgaatgt
     7921 attgtaagtt aagatcaata cttaatcgct gacctagaac atccaataga aaattttgcc
     7981 cgtaagaaaa gatagagttg aaaacatatg ctatcaataa accaatagct aggatcgaca
     8041 aagtttggta tgtaccgcta ggaatataag tatcaattaa gccttgcaag aagtatgagc
     8101 tacaaatact aatgattgtc atcaaaagag cagccaaaat aatattagtg actagtttct
     8161 tttgtttgaa catgtatgga aatagtgacc acagattttg ctttttctct ttgagtggct
     8221 caaaatcatc atttgggacc ataaaaaggg caattcccgt ccattcttga gaaaactttt
     8281 ctttagacat tttcgttaaa ccaacgctag gatccggatc agcaatcact aaataatttt
     8341 tggttgcctt aatcacaaca taatagtgga gtaattcgcc ttgctttaag acgtgtacga
     8401 tgaaaggata ttgaatgtct gcatcaggat caaacaagga catgtcagct ttaactgctt
     8461 cagtttttag attaaatgct tgtgctgttt taactaagcc cagagcggta gtcccttcta
     8521 aattagtgcg ggctgaatga cgtaaatggg ctaaaaatac tctagaatga tattttttaa
     8581 gaatcatagc taagcatgca actccacaat ctgattcgtc tacttgtggt acataaattg
     8641 atttatactg tagtaacatc ttttccactc ctcatattaa gttgaatcca ttatttcatg
     8701 attggaaaac taaatgtaaa aaaataccaa atcggttatt ctcattaccg attcggtatt
     8761 ttagttttct aactagattg agctactcaa ctttaatatt ttcaaattta tctacaagct
     8821 ttttaaccac ggctttatac gatctagaat aagttaccat ctgaccatta tcaaatataa
     8881 taatgcgttc cttcgtgtca attgcactaa tgttcttagg atttaccaaa gaagattgcg
     8941 aaacttttgc caagaatggg ttttctttat caatctgagt aatatttgcc ttatactcaa
     9001 cttctccatt ctcagtaacc atatgtactt tatgctgtgt agtactgtgt tcaatgaaaa
     9061 gtatatcgcc ttcggccact ttacatacgc gccgaccaat cttataagta aagtcacgtt
     9121 gactaaactt aattctgtta gataaattat cgaaggcgtt acgtaacgtt tcttcgatac
     9181 gttgaataat cttatcagac gacatagact tactaatata atcaattgca ccgatacgac
     9241 ggcgatacgt taatggagcg tacttatcgt acgccgttac gaagatgatc tgggcatttt
     9301 cgtcattctt cttgatgaat tcagctaaat ctacgccatt cttagcttta gactctcgac
     9361 ttaattcaat atctaagaag tagataccat tcttaatatc atttgtgact atgtatccta
     9421 ccgcttgagc aaaatcgtta gcaacaaacg taacagattc atttaattca gcgtaacctt
     9481 cattatcatc tattaagtct tgaatagatg cattgatatt cttagccatc tgattagcta
     9541 aatctttatc gtcatcgcat acaatgattg ggaacttact catcctcttc accatcttcc
     9601 gtatcaattg tcatataaaa gtcgaaccag ccgtcttgaa ttgtataaga aatagacata
     9661 tcaggatatt tactctcaat ttccttaata ttagctaatc caagcccttt atggtctttc
     9721 ttagtagtaa agccacgttg ttgaatttga ctagttgaga tatttttatt ttggatttta
     9781 tttctgattt cgaactcaaa ttcatctggg tcatcagaat agaccattat ttggacttca
     9841 gcacttcgaa tatcatgctt ttcggcaatc aatgctttac tttcctcaat tgcattatcg
     9901 aaagtaatgc caataatacg tactagatcg agttcatcta catggtctgg taaattacgg
     9961 atattatttc gacattcaaa attatatggt atatccaaat tatacaattc tgttatcttt
    10021 ggaataataa tgctcttaat tgatttaacg taaatgtgat ttaggtcttt atatttaagt
    10081 aaggctttag aatttaggtt agtttcagta tatttatcta gtttctgaat tacttcttga
    10141 acgttacctt cttgcgcact tacctttaaa gaattaagaa tatttttgta atcatgtctg
    10201 aaggcgcgaa gatcatcttc acttttttca agataagaag catattcttc aagctgatgc
    10261 tgctgttgct ttaatttttc ttgatccttt ttatttaaaa gtttttcttg taccatcgtc
    10321 atttcatgat atataaatat agcaaaaata gtttggataa gaatatagag agaaaagaac
    10381 aaagttaatg gtgtaaaaga tttgctttga atatatatga tagagatgct caccgtagaa
    10441 acataggtat aagctaatat gcctacgaaa attttattat tttggtttgc tagataatta
    10501 tatatttttc cattacctag ttttattgca actatcatca ttagtattag taagaaacgt
    10561 agtgataatt ggcctatcaa agtaaatgac ataacctgag tgatcatatc agacacaata
    10621 tcaactaata aatctaatgt gcatactaat attattgaac caaatagtat ttctaatgta
    10681 ttattttttc tcaaatataa tacaaaaagc aaagtttcaa gtatatttgt gaagattacg
    10741 ccaatattac ctatagacaa taacaaccct aaaaaaatat tagcaataca caaaaataga
    10801 atctgtctct ttttagatct tactcttgat attttaaaaa aacaccatac atctgctaaa
    10861 ctagaaaaaa cattaagaaa aagaaataag actatctttt ccatatatta ttccaaagtt
    10921 ttttactcaa gaaattaaaa ccaacatgtg ccgtgcttcc accaacaacc ttagtcaatt
    10981 cttcttcctt caaaacagtc tttttaacat tttgcttctt catgatattt catcctttca
    11041 tgattttata ctcaacttgt ttacaccttt aatatatcat gtacttttaa gtaaattaaa
    11101 aaagatacca attcagtcat actttcgtac cgatccggtt tcatatttct tcaaacgtaa
    11161 acaactgaca attaattttc ttagctaatt cctgacagct atccgtaaag ccagatttgg
    11221 aaaatagata ataatgctta agtggatact tgaagatttc actatttgta atcaattttt
    11281 ctaacacact acgagagatc ggttcattct tccatttaca ttcgccgaaa tatccatcac
    11341 gttcatcgtc agagaatcct acaatatcta actcaacttg ttgatgtgtt ctcttatcgg
    11401 ttccccacca attgcccaag tggataaacg gattaggaac aattttttca ttcatatcct
    11461 gagaccacat gaagtcttga ctgtattttt caaactcagg tcccatgaaa tcagatagac
    11521 ccttttgtac ttttacccaa gcaagatcag ttaagccacg ctcaattaga tcggtttgct
    11581 tgccaacaaa ggtataccag aagcggaaca tcccgtcaca gatacgataa acgatatttt
    11641 tgcttttact cttcttttgc tcagtaaccg gtaacttttt ctcaacaata cctaaatcta
    11701 tcaaattatt caggtacgtg gttagcggac cagtttgtaa gtgggcggat tgcgcaattt
    11761 tactatgctt agaagcacct gaagctatcg cattgataat cgaattatag ttagttggat
    11821 cgcgtaattc ctgttgtaac aagttattag gctcatcaaa taagcgacct gatttactca
    11881 aaaagttttt cttaatatta tccgcaactg acatgctgtc tgacatataa ctcaaatatt
    11941 ggggtacacc gccacaaacc gtattgatga taaaagcgtc ctctttactg agttttggta
    12001 acatttcatg tgcttctgat aatttaaatg gttcaagctt taaggctaaa gtgcgacgac
    12061 catatagtgg actttggtag cctaagactt gtcgttccat aaatgacatc gatgaaccac
    12121 ataaaatcaa aaataggtta gtttctttga attcatgatc aatgtaggat tgcaacattg
    12181 aactaattgt agggtaagcc ttagccaaat aaggaaattc gtcaataact aaaattacac
    12241 gttgtttttg agctaggtgt gtaatttctt taaagcattc ctcaaaattt gcaaattttt
    12301 cttttccacc ctgatctgta tttttaaaaa tactaattgc atcagaaaaa cgttttagat
    12361 tatcttccgc attttcttca agtgctacat aataaattga ctttttatct tttaaaaact
    12421 cattgatcag tgaagtcttt ccaattcttc ttcgaccata gatcactgta aattgaaaat
    12481 cattttcttg atacgcctga ttcaattgct ctaattcttg atgtctacct acaaacatag
    12541 cgcactcctt ttcactacat cgtaatatac tacattatat tatactataa cacgatatag
    12601 tataacgtaa tgtacgtgta ttctattttt gtaataaaaa tggccgttac ttagagaaat
    12661 agcgaagatc attaaatttt aacatgctat aataacaata gaacaagaat aaaaagtttt
    12721 agcgtgcgcg ttgaggtagc tcctcaactt agtcattaac gtgtggctct gctttggcaa
    12781 agcttttttg ttatgttaat accctacaaa aaagaccgtg catccctgca cggtcttttc
    12841 atcttatcac atctattttc taacgtattc gccgttcttg tacttaaatt caatcttctt
    12901 gttaggcaat tgaaccgtaa ttctgcgata tacaggaccg aagccgtgct tttcaagctt
    12961 aactttcacg ctaccgtcct tgtttacctt aaccttgtac aagttgtatt cgcccttttg
    13021 gtacttaaag tcagttccgt tatcttgata gtgaacgtac ttaccctttt taccaaatag
    13081 tctaaaggtc atactctcgt ctggttcacc agagatgtgg ctaacttctt taccccatgg
    13141 caagatagtg ttcttcttga taaacagtgg caacttgcca attggtgcat caaccaaaat
    13201 cgtggtcttt ccagcatgtt caacaccatt ccagaaatca atccattttc cttttggcaa
    13261 atatacggca cgcttggttt gaccttcttg aacaactggg gctgccaaaa tgtcctcgcc
    13321 taccatatat tcatcattca agttatacac ctgtggatca ttttcataat taaggacaag
    13381 tggacgcata attggcaaac ctgtcttagt ttcacgatag aattcatcgt aaagatatgg
    13441 aatgaaacgg taacgcagct tcaagtactt acggtaaatt gacaaggttg gttcgccaaa
    13501 tatccatggt tcttgtgagc gagttcctag agccgcatgg tttctgtaca atggactaaa
    13561 caatgcgcct tcgatccaac gagtcaa
//
