LOCUS       c00118_JAJAOX0..       15873 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAJAOX010000301.1 Limosilactobacillus reuteri strain QAULRN15
            NODE_300, whole genome shotgun sequence.
ACCESSION   JAJAOX010000301
VERSION     JAJAOX010000301
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-20 18:24:10
            Original ID  :: JAJAOX010000301.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15873
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15873
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1038:7506]"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1039..7506
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
     cand_cluster    1..15873
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /kind="single"
                     /product="Nitrate_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15873
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Nitrate_reductase"
                     /region_number="1"
                     /rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /tool="gutsmash"
     CDS             80..970
                     /locus_tag="ctg118_1"
                     /transl_table=11
                     /translation="MNIKSVPKKQLWGIELNLVSLLFSSISPVLNKFSLTSLSPVVGGI
                     FTSAFAAIFTFATILITRQHVSLTNLKSLWLWLLGGTNAIGIILQYIALSTLSPITVTL
                     IARMYLVYVFLLSYIFLKEKITKWDYLAIILCILGSFFISGSRLQFSDNLLGLICAFIY
                     PLMYAANNIVAKYLVSDEEPNNVLFFNHFTSALLLFCYALITGTSFSHISSQAVAFNFG
                     GAFFNGFMSLLLFYTSLQFITAGKANIVRALGPVIVIIYSSFFFPVQVTPSLFLGAILV
                     ILASTIVTFTRTNHE"
     CDS             complement(1039..1728)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_gam"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_2"
                     /sec_met_domain="Nitrate_red_gam (E-value: 1.2e-77,
                     bitscore: 250.4, seeds: 140, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNGWSIFLWVIYPYIMLASFFIGTFVRFKYFHPSITAKSSELFE
                     KKWLMIGSVTFHIGIILAFFGHCLGMFIPASWTAYFGITEHMYHIFGSLMMGIPAGILA
                     FVGIAILTYRRMTCSRVYKTSDINDIIVDWALLVTIALGLACTITGAFIDYNYRTTISP
                     WARSLFVLNPQWQLMRSVPLIYKIHVLCGLAIFGYFPYTRLVHALTLPWQYIFRRFIVY
                     RRRARVY"
     CDS             complement(1721..2299)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_3"
                     /sec_met_domain="Nitrate_red_del (E-value: 1.4e-09,
                     bitscore: 28.2, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIDFRRLTDLKDTFAVLSRLIDYPDTETFSPEIRQLLLTDNALST
                     ATRGELLSLFDELAALSSIEVQEMYAHLFEMNRRYTLYMSYYKMTDSRERGTILARLKM
                     LYEMFGISEATSELSDYLPLLLEFLAYGDYTNDPRRQDIQLALSVIEEGTYTLLKNAVT
                     DSDSPYIQLIRLTRSLIGSCIKMEVQEDA"
     CDS             complement(2292..3851)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_bet_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Fer4_11"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_4"
                     /sec_met_domain="Fer4_11 (E-value: 3.3e-39, bitscore:
                     123.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00052, bitscore: 10.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_bet_C (E-value: 1.9e-28,
                     bitscore: 88.2, seeds: 110, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIKAQISMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNVE
                     TKPGVGYPKRWEDEDQYHGGWTLNSKGKLKLRAGSKLNKIALGKIFYNNDMPELDNYYE
                     PWTYDYKTLFGPEQKHQPVARPKSQITGEGMELTTGPNWDDDLAGSTEYVQQDPNMQKI
                     EGDIKNNFEQAFMMYLPRLCEHCLNAPCVASCPSGAMYKRDEDGIVLVDQERCRGWRFC
                     MTGCPYKKVYFNWKTHKAEKCTFCYPRIEEGQPTVCAETCVGRIRYIGAILYDADRVEE
                     AASTPDESKLYEAQLGLFLDPNDPEVVKQALKDGLSEEMIEAAQKSPIYKMAVKEKIAF
                     PLHPEYRTMPMVWYIPPLSPVMSYFEGRDSIKNPEMIFPGIDQMRVPVQYLASLLTAGN
                     VPVIKKALYKLAMMRLYMRAKTSGRNFDSSKLERVDLTEKRATSLYRLLAIAKYEDRFV
                     IPSSQKAEMEDAQIEQGSLGYDECEGCALAPQHKSMFKKAEAGKSTNQIYADSFYGGIW
                     RD"
     CDS             complement(3841..7506)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_alph_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molydop_binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molybdopterin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_5"
                     /sec_met_domain="Molybdopterin (E-value: 2.7e-141,
                     bitscore: 461.4, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 1.2e-23,
                     bitscore: 73.4, seeds: 74, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_alph_N (E-value: 1.1e-08,
                     bitscore: 25.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSRFFNKVDKFNGTFTQLEENSRRWEKLYRQRWAHDKVVRTTHG
                     VNCTGSCSWNVYVKQGIITWEHQATDYPSCGPNIPGYEPRGCPRGASFSWYEYSPVRIK
                     YPYIRGKLWELWTAAKKEHENPLDAWASIVEDPEKSKKYKKVRGHGGLIRVHRYEALEM
                     ISAACLYTIKKYGPDRIGGFTPIPALSMMSFSAGARFIALMGGEQMSFYDWYADLPPAS
                     PQVWGEQTDVPESAEWYNSSYIIMWGSNVPLTRTPDAHFMTEVRYKGTKIVAVSPDYAE
                     NVKFADDWLAPEPGSDSAVAQAMTYVILDEFYQKHPIKRFIDYSKRFTDLPFMVELEPS
                     TANGDHYTPGRFVRISDLIADDTIVNPAWKTVVYDQNNHKIVVPNGTMGQEYNAKEKWN
                     LELLDQNGNKIDPALSINDQDGETEQIIADFPAFSNDGNSVVQRHLPVKKLKFTDGKEH
                     LVTNVYDLMMAQMGINRTGNDELAAKDAMDAESYFTPAWQESRSGVKAEQVIQIAREFA
                     QNAAENEGRSMVIMGGGVNHWFNADMNYRNIINMLMLCGCVGMTGGGWAHYVGQEKLRP
                     QEGWANITFANDWEKGGARQMQGTTWYYFATDQWRYEEIDNQAQKSPVWKSKHSYLHNA
                     DYNQMAIRLGWLPSYPQFDRNPLSFAKDYNTTDINEISKKVVDELKKGSLHFAAEDPDA
                     NQNQPKAFFLWRSNLFASSGKGAEYFMKHLLGAENGLLAKPNDRVKPQDMIWRDKGAVG
                     KLDLVVDMDFRMVSTPMYSDVILPAATWYEKKDLSSTDMHPFIHPFNAAVSPMWESKSD
                     WQQFKLLAKTVSEMAKKYMSGTVYDLKSAPLGHNTQGEIAQPYGKIKDWKNGETEPIPG
                     KTMPSLKLVTRDYTKIYDKFITLGPNIVNNYGYKVDDQYDYLKGMNGTASEGIGAGCPL
                     LDEDEKVCDAILRMSTASNGKLADRAWEKKQERTGEHLTDIGRGHADDSMSFKQITAQP
                     QEAYPTPIGTSAKHGGARYTPFSLMTERNIPTFTLTGRQHFYIDHEIFREFGENMATYK
                     PSLSPVVMAPGDVDVPPVKDEVTLKYMTPHGKWNIHTMYYDNLEMLTLFRGGPTIWISP
                     QDADKIKVKDNDWIEVYNRNGVVTARAVVSVRMPEGSMYMYHAQDNEIYEPLSTITGNR
                     GGSHNAPTQIHVKPTHMVGGYGQLSYGWNYYGPTGNQRDLYANVRKLKKVNWSED"
     CDS             7651..8670
                     /locus_tag="ctg118_6"
                     /transl_table=11
                     /translation="MNRYDRQERVHQIGSIGQQKISHATIMIVGVGALGSYTAEQLVRA
                     GVKRLVLIDPDIVDVTNLQRQSLFTEEDANQQRLKVEAAKEHLHEINSACQITAIPAPI
                     TADLIDEYQFTLCLDCLDNYQARDLLNKLAIIKNFDYLFASCAGTYGNVMAISPQNHPC
                     LNCLFPNINELKQNDCDLIGVNTALIPIVAGLQVSLALHYLVDKTQVNFNELITVDNWS
                     MQFSKFAINKNCHCPACAKPSSIFLEEESAPELHMLCGENAYYTVKEKPINFGRLKEFL
                     AKKELLINANRLFLHFKWENRPVSIFKNGKIVMYDLPTSAIAQKQFESLNILMKEDLL"
     CDS             8667..9164
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_7"
                     /sec_met_domain="MoCF_biosynth (E-value: 6.3e-34, bitscore:
                     106.8, seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIAILTVSDSRTLDSDTSGKLIVMKMANAGLSVVDRVIVNDDI
                     VNIQTAYLQLEQQAIDIIITNGGTGVAQRDVTIPAIRPLLKRLIPGFGEAFRQISFDEI
                     GTRALASQALAGFNYRNQLTYCLPGSQNACQTALNKLILPEYEHLLFESSSQRKEVHHH
                     AH"
     CDS             9154..10371
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_8"
                     /sec_met_domain="MoCF_biosynth (E-value: 1.2e-23, bitscore:
                     73.5, seeds: 114, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_C (E-value: 5.2e-13, bitscore: 39.2,
                     seeds: 41, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_N (E-value: 2.7e-38, bitscore: 121.3,
                     seeds: 1302, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRRIPISVAEAQKKINEIPLKTAADTIPLSEANHRVLAKDVHA
                     NYDYPHFRRAGMDGYAILASDDHDFPREFNVRGEIQAGATWDQPLQSGDAVRIMTGAYV
                     PSDVGKVIRIEKTRPAKDENKVQIITTESKTNITEAGTDVKSGDIVLAKDQEINPGGLA
                     VLTAFGVQEVAVYKKPRIAIIATGTELLGPNDTIEPGKIFNSNGIMLKNLVEETGGIVD
                     FETQLPDDAELIKRTLEEQMATHEIVITDGGVSVGDFDFIGDEARKADELLFNKIKQRP
                     GSVTTAFVQNNTLIMALSGNPGACFTGFYLYMEPLIRRYQHQASRIKQVRAILAAPYNK
                     TNGFDRYLRCTYEFKENQFYIYPNGINRSGSLANLQTTTCLALIPHSTTPMKVGTETDA
                     WLLPFK"
     CDS             10350..10841
                     /locus_tag="ctg118_9"
                     /transl_table=11
                     /translation="MAITLQIIGHKKSGKTLITTTLIERLAKEGYQVAALKHDAHNATM
                     DVPTTDSARMSNAGAKQVILQSATEFFFHQKSNVPPLTEMVELLSAENDFVLIEGHKEA
                     TQYPQILLLKPGEDPANIVPTPPLKTGSIFRGTTADLLGKDAIVSWCYNYLKQIKGDAG
                     "
     CDS             10838..11410
                     /locus_tag="ctg118_10"
                     /transl_table=11
                     /translation="MIGLVYAGGKSTRFGKDKATYHIPGLPVTNIELAVEKLTPFCQQI
                     VVCANEINRAHILKLVGQGPAVQIICDIPPYDHHGPLSAIIACTSHFSTLQDYLTLAVD
                     YPYITKDSLAVLARTSNSYIATSQHSHYSLAHFSISNEQVTTWVADNDDWRLRSFITNK
                     CVCHPLVYRSSAEFSNLNYREVDLNEK"
     CDS             11400..11684
                     /locus_tag="ctg118_11"
                     /transl_table=11
                     /translation="MKSKDSMTNPDFQKLISLVLNDLTIRRTMLENREQEVSQQMSSLE
                     KDAELEQLDDQIQQIQADFDHYREFQDPKFEFSATKYFQGPSMGLPGHP"
     CDS             11823..12881
                     /locus_tag="ctg118_12"
                     /transl_table=11
                     /translation="VLETANWIQKYFNQSPDAIFLFKNDDLLVSNEPAQRLVTVLNLNV
                     NYLLQIGKNAWSQLENDDCASCLIKKRLKGAVVPITFHSNATHPFHFSMVYRPLDDKEN
                     VFALNLENREQQQRLSQIEEHRILNQYVNEAREKERQKISQDLHDSVAQGIYAAIMGIQ
                     RLATVQNQRNTEQFQSMSAAIEKQLQTTLKEIKGIALDIRPSVLDNFGLIPAIKALAKR
                     LQNSTGITIDVIALTSAEKLQKNIQNVLYRITQEAINNAIKHAHSTEISIIVTDHDSYL
                     QLEILDNGIGFDIDQHSGFNGHSLGLMNMNERVKAYNGAFTITSKINKGTTVKVKFPYN
                     NALNKDMVRTNG"
     CDS             12874..13527
                     /locus_tag="ctg118_13"
                     /transl_table=11
                     /translation="MDNVLVADDHAIVRSGISYLVDLQPNFTVVDGTASGTDTYIRVEQ
                     GGIDILIMDLSMPPGENGLITTRRIHDKFPKVKIIILSMHEEQEYINKAMANGAMSYIL
                     KSSPDSEIVNALKHVINGEKYLDANIIVSKTDIREINASGNTLKLKGYNSLSKREKEVF
                     PLIALGYSNKEISQKMFISTKTVEAHKANISRKLHLHGRVELVQYAIHHHLIDL"
     CDS             13624..13896
                     /locus_tag="ctg118_14"
                     /transl_table=11
                     /translation="MAANLSRDDELQGILSDVARKRFINSRQVNPVSNLFLTTKYAVEK
                     QYISGAVIDESFSSTLAEINLKNAVLTDRGRNKLEQLLTQSTKEN"
     CDS             13902..14870
                     /locus_tag="ctg118_15"
                     /transl_table=11
                     /translation="MDIQDKLKRDYENKSIYTAGFYADPDNELANRKKLFDALKSLVEN
                     QAATTPFALQIMLTNGEINVMPLGLVDLEELKKYESEQRSKHGLDEHNDDIPLLIQYAP
                     HAEKKEVVKKRIGTIQDLFTNFNEQIEKIWQTVKEFMQDNFALLTTIEKDLIADSQNVM
                     HEYQITFSKMTEAERKEKLGFSVPENEVNQFCRYMADMHEVQAIVLSAGAFVNHELLGK
                     NSFTEMISDNIRRSTLFWVLDNTFYEIYYYFYMSNDNDKLHKRLKHQREALIVNMRNDA
                     FHRAQEFTEKQAKNVDFNEYFSDIFIPVAEQIIAEVNKFKD"
     CDS             14875..15783
                     /locus_tag="ctg118_16"
                     /transl_table=11
                     /translation="VNLTPDERLVDALTTIIYQYPPMVREMINLSTGEEERRLRLSLFE
                     TFSYFNEKELTIDQITAAQLPELLALSTHLNSPSFQPNNLTPGEFASQKAYSYVASYLM
                     NRFVRSLSTVGNPPQVIEELTTDAGDVMLAQIQRLQFNYNQQFKVADYLADAKARWGLL
                     GAMTAKQSAVLSGAGNEVVSLAGQIGQALGTASYITHEFQQLSNDPDSFVKMITSGQYP
                     LALLFARQQNPQWFSNFFASDHRPSQAMFKQAHQLALERIDDVKQLIADIFSQLILDIK
                     VLPAGQVQDKLLSLAEELKKE"
ORIGIN
        1 acgtcactga tgagcaacta ttttctttct aacttaaatt gacatttcgg gagtaataaa
       61 atgtattgga tgtgactaaa tgaatataaa aagtgtccca aagaagcaat tatggggaat
      121 tgaattaaac ctggtttctc tcctatttag tagtattagt ccagttctaa acaagttttc
      181 acttactagc ttaagtccgg ttgttggagg aatctttact agtgcgtttg ctgcaatttt
      241 tacttttgca acaatcctca ttactcgtca gcatgtttct ttaaccaatc ttaagagcct
      301 gtggttatgg cttttgggtg gaacaaatgc aatcggaatt attcttcaat atattgctct
      361 ctcaacctta agtccaatca cagttactct tatcgctcgg atgtatttag tttacgtttt
      421 cctcctatct tatatcttct taaaggaaaa gattacaaag tgggattact tagcaattat
      481 tctttgcatt ctcggttctt tctttatttc aggaagccgt cttcaattta gtgataacct
      541 tcttggattg atttgtgcat tcatctaccc actaatgtat gccgccaaca atatcgtggc
      601 taagtatcta gttagtgatg aagagccaaa taatgtctta ttctttaacc attttacttc
      661 ggctctttta cttttctgct atgctctcat aacaggaacg tcatttagcc atatttctag
      721 tcaagcagtt gcatttaact ttggtggagc attctttaat ggcttcatgt cactacttct
      781 tttctatact agcttacagt ttattacagc tggtaaagca aatattgttc gtgcacttgg
      841 tccagtaatt gttattattt actcttcatt tttctttcct gttcaggtaa ctccttccct
      901 atttttagga gctattttag taattttagc tagtacaatt gttaccttta caagaacaaa
      961 tcacgaataa tcgtaatata aaagcatcag aatttccctg taaagaaatc tgatgctttt
     1021 attatatctt cttatatact aataaaccct tgcacggcgc cgatagacaa taaaacgacg
     1081 gaaaatatat tgccaaggta gtgttaaagc gtgaaccaac cgggtgtatg ggaagtaacc
     1141 aaaaattgct aatccacaga gaacgtgaat cttataaatc aatggcactg aacgcatcaa
     1201 ttgccattgt ggattaagaa caaatagact tcttgcccat ggactaattg ttgtccgata
     1261 attgtaatca ataaatgcac ccgtaatagt acatgctaga cctaatgcaa ttgtaaccaa
     1321 taaagcccag tcgacaataa tatcattgat atcacttgtc ttataaacac gagaacaagt
     1381 cattcgccga taagtcaaaa ttgcaattcc gacaaatgca aggatccccg ctggaattcc
     1441 catcattaat gaaccaaaga tatggtacat atgttcagta atcccaaagt aagctgtcca
     1501 acttgccggg ataaacattc ctaagcagtg accaaagaaa gctaaaataa ttccaatgtg
     1561 gaaagtaaca cttccaatca ttagccattt cttttcaaaa agttcacttg atttggcagt
     1621 aattgaggga tgaaaatatt taaatctaac aaatgttcca atgaaaaatg atgccaacat
     1681 tatatatgga taaataaccc ataagaaaat tgaccagcca ttatgcatct tcttgcacct
     1741 ccattttaat acacgaacca attaatgaac gtgtaagcct gattaactga atatagggac
     1801 tatcactatc tgtcactgca ttttttaaaa gggtataagt tccttcttca atcacactta
     1861 atgctaattg gatatcctga cgacgcggat cattagtata atcgccatat gctagaaatt
     1921 ctaacaatag aggcaaataa tcagaaagtt cactggtcgc ttctgatata ccaaacatct
     1981 catatagcat tttcaaccgt gctaaaatgg tccctcgttc acgggaatcg gtcatcttat
     2041 agtatgacat ataaagagta taacgtcggt tcatttcaaa aaggtgagca tacatctctt
     2101 ggacttcgat tgaagatagt gcggctaatt catcaaaaag gcttaataat tctccacgcg
     2161 ttgctgttga taatgcgtta tctgtaagta ataattgacg aatctctggt gaaaacgttt
     2221 ctgtatcagg atagtcaatc aaacgggaaa gaacggcaaa tgtatccttt aaatctgtca
     2281 atcgtctaaa atcaatcacg ccaaatccct ccatagaaac tatcagcata aatctgatta
     2341 gttgatttgc cagcttctgc cttcttaaac atactcttgt gttggggagc taatgcacag
     2401 ccttcacatt catcatagcc aagactacct tgttcgattt gtgcatcttc catttctgcc
     2461 ttttggctac ttggaataac aaagcggtct tcatatttag caattgccag taaacgataa
     2521 agtgatgttg cccgtttttc tgttaaatcg actcgttcta gtttactgct atcaaaattc
     2581 cgaccactag tcttagcacg catgtatagc cgcatcattg caagtttata taaggctttc
     2641 ttgatgacag gaacgtttcc agcagttaat agacttgcca agtattgaac aggcacccgc
     2701 atttgatcaa ttcctgggaa gatcatttca ggattcttta ttgagtcccg tccttcaaag
     2761 taactcataa ctggtgatag cggcggaatg taccaaacca ttggcattgt ccggtattct
     2821 gggtgaagtg ggaaggcaat cttttctttt actgccattt tatagatcgg tgacttttgt
     2881 gcagcttcaa tcatctcttc agaaaggcca tccttgagtg cttgcttgac aacttcagga
     2941 tcgttgggat cgaggaataa gccaagttgt gcttcataca gcttactctc atcaggagtt
     3001 gatgctgcct cttctactcg atcagcatcg tatagaatag caccaatata tcgaattcga
     3061 ccgacacagg tttcggcgca aactgttggt tgaccttctt caattcgtgg ataacaaaaa
     3121 gtacattttt cagccttatg agtcttccag ttaaagtaga ccttcttata tggacatcca
     3181 gtcatgcaaa aacgccatcc ccgacagcgt tcttggtcta ctaaaacaat cccatcttca
     3241 tctcgtttgt acattgcacc tgatggacaa gaggctacac aaggcgcatt caaacagtgc
     3301 tcacataatc ggggaagata catcataaat gcctgctcaa agttattttt gatatcccct
     3361 tcaatttttt gcatgttagg atcctgttgg acatattcag ttgatcctgc taagtcatca
     3421 tcccagttag gaccagtggt taattccatt ccttcgccag taatttgcga cttaggacga
     3481 gcaacaggtt gatgcttttg ttcagggcca aataacgtct tataatcata ggtccatggt
     3541 tcgtagtagt tatctaactc tggcatatca ttattgtaaa aaatcttgcc aagagcgatt
     3601 ttatttaatt tgcttccagc acgtaatttt aatttacctt ttgaattaag ggtccaccct
     3661 ccatggtatt gatcttcatc ttcccagcgt tttggataac cgacacctgg cttagtttca
     3721 acattattaa accacatgta ttcagcgcct ggacgatttg tccatgtatt cttacaagtt
     3781 actgaacagg tatgacaacc aatacactta tcgaggttta agaccatgct gatttgtgct
     3841 ttaatcttca ctccagttca ccttcttcag ttttcttaca tttgcataaa gatcacgttg
     3901 gtttccagtt ggtccatagt aattccaacc gtaactcaat tggccatatc ctccaaccat
     3961 gtgtgttggc ttaacgtgga tttgcgttgg tgcattatgt gatcccccac gattaccggt
     4021 aatggtggaa agaggttcat aaatttcgtt atcttgggcg tggtacatgt acattgaccc
     4081 ctcaggcatc cgaacagaaa caaccgcccg cgcagtaaca actccattac ggttataaac
     4141 ttcgatccag tcgttatctt ttaccttaat cttatcggca tcttggggac taatccaaat
     4201 agttggacca ccccggaata atgtcaacat ttcaaggtta tcgtagtaca tcgtatgaat
     4261 attccattta ccatgaggag tcatatattt aagtgtaact tcatctttta ctggtggaac
     4321 atcaacatct cctggggcca ttacaactgg tgataaggat ggtttataag ttgccatatt
     4381 ttcaccaaat tcacggaaaa tttcatgatc aatgtagaaa tgctgacgac ctgtaagagt
     4441 aaatgtagga atatttcgct cagtcattaa tgagaatggt gtgtatcgag ccccaccatg
     4501 tttagcagaa gttccgattg gtgttggata ggcttcttgt ggttgagcag tgatttgctt
     4561 aaatgacatt gaatcatcag catgaccacg gccaatatct gttaaatgtt caccagttcg
     4621 ctcttgcttc ttttcccagg ctcggtcagc gagtttacca ttggaagcag ttgacatccg
     4681 taagattgca tcacatactt tttcatcttc atcaagtaac ggacagcctg caccaatgcc
     4741 ttcgctggca gttccattca ttccctttaa ataatcatat tgatcatcga ctttatagcc
     4801 atagttattc actatattag gtccaagggt aatgaattta tcgtaaatct tggtgtaatc
     4861 acgagtaacc aatttcaagg aaggcattgt ttttcctgga attggttcag tttcaccatt
     4921 cttccaatct ttaattttcc cgtacggttg agcaatttct ccctgggtat tatggccaag
     4981 tggtgcactc ttaagatcgt aaactgttcc tgacatgtat ttctttgcca tttcagaaac
     5041 agtttttgct aagagcttga attgttgcca gtcagacttt gattcccaca ttggactaac
     5101 tgctgcatta aatgggtgaa taaatggatg catatcagtt gatgaaaggt ccttcttttc
     5161 ataccaagta gcagctggta ggataacatc ggagtacatt ggtgttgaaa ccattcggaa
     5221 gtccatatca acaacaagat ctaacttacc aactgctccc ttgtcgcgcc aaatcatatc
     5281 ctgaggctta acccgatcat taggtttagc aagcaatcca ttttcagcgc ctaataaatg
     5341 tttcataaag tattcggcac ccttgccaga agaagcaaat aagtttgaac gccataagaa
     5401 gaacgctttg ggttgatttt ggttagcatc aggatcttca gcagcaaaat gtaaagagcc
     5461 cttcttcaat tcatcgacaa ctttctttga aatttcatta atatcagttg tattgtaatc
     5521 ttttgcaaaa gatagcggat tacgatcaaa ttgtgggtat gatggtaacc atcctaaacg
     5581 aattgccatt tggttataat cagcattatg taagtaagag tgtttactct tccaaacggg
     5641 tgacttttga gcttgattat caatttcttc ataacgccat tgatcagttg caaagtaata
     5701 ccaagtagta ccttgcattt gacgggcacc acctttttcc cagtcattgg caaaagtaat
     5761 gtttgcccaa ccttcttgtg gacggagctt ttcttgacca acgtagtgag cccaaccacc
     5821 gccagtcata ccaacacaac cgcacaacat cagcatatta ataatatttc gatagttcat
     5881 atcggcattg aaccagtggt tgactccacc acccatgatt accatacttc gaccttcatt
     5941 ttcggccgcg ttttgggcaa attcacgagc aatttgaata acttgctctg cttttactcc
     6001 cgaacggctt tcttgccaag caggagtaaa gtaactctca gcatccattg catctttagc
     6061 agcaagttca tcattaccag tccgattaat tcccatttga gccatcatca gatcataaac
     6121 attagttacc aagtgttctt tgccatctgt gaatttgagc tttttaactg gtaaatgacg
     6181 ttgcacaacg ctgtttccgt cattactaaa tgctggaaaa tcagcaataa tttgttcagt
     6241 ttcgccatct tgatcattaa tagaaagtgc cggatcaatc ttattaccat tttggtctaa
     6301 taactcaaga ttccattttt ccttagcatt atattcttgt cccatcgttc catttggaac
     6361 aacaattttg tggttatttt ggtcataaac aactgttttc catgctggat tgacaatcgt
     6421 atcatcagcg attaagtcac taatccggac gaagcgacct ggtgtatagt gatcaccatt
     6481 tgctgtactt ggttccaatt caaccataaa tggtaaatca gtaaatcgct tggaataatc
     6541 aatgaaacgt ttaattgggt gcttttggta gaattcatct aaaattacat aagtcatcgc
     6601 ttgagcaaca gcagaatcac tacccggttc tggtgcaagc caatcatcag caaatttcac
     6661 attttcagca taatcagggc taactgctac aatctttgtt cctttgtacc taacttctgt
     6721 catgaagtgt gcatctggtg tccgagttaa tggaacgttt gatccccaca taataatata
     6781 ggaactgtta taccattctg cagattctgg aacatcagtc tgttcacccc aaacttgggg
     6841 agatgcaggc ggtagatcag cataccaatc gtagaaactc atttgttccc cacccattaa
     6901 ggcgatgaat cgggctccgg cactgaaact catcattgac agtgcaggaa ttggggtaaa
     6961 accaccaata cggtcgggcc catatttctt aattgtgtat aagcaagcag ctgaaatcat
     7021 ttctaatgct tcataacgat gaacacgaat taagccaccg tgtcctcgga cctttttata
     7081 ctttttagac ttttctggat cttcgacaat acttgcccac gcatctaagg gattttcatg
     7141 ttctttcttg gcagcagtcc aaagctccca taatttgccg cgaatatatg gatacttaat
     7201 tcgaacggga ctgtattcat accaagagaa actagctccc cgaggacatc cccgtggttc
     7261 atatcctgga atattaggtc cgcatgatgg ataatctgtg gcttggtgtt cccaagtaat
     7321 aattccttgc ttaacataaa cattccaaga acatgagcct gtacagttaa ctccatgggt
     7381 tgttcggaca actttgtcat gcgcccatcg ctggcgataa agcttttccc aacgacgact
     7441 attttcttca agttgtgtaa aggttccatt aaacttatca accttgttaa agaaccgtga
     7501 cttcatcgtt gattgacctc ctttattgaa tggcttacca atattaaaaa taaagtaagt
     7561 cttttcccta atataaagat tagcaccata actgctatac tacgactagg gaaataccta
     7621 tattttgaac taaatgaggt gctaatatcc atgaatcgtt atgatcgtca agaaagggta
     7681 catcaaattg gtagtattgg tcagcaaaaa attagccatg caactattat gattgtcggt
     7741 gtaggggcat tgggaagtta tacagccgag caacttgtcc gtgctggagt taaaagactt
     7801 gtcttgattg atcctgacat tgttgacgta actaatcttc aacgtcaatc gcttttcacc
     7861 gaagaagatg ctaaccaaca acgccttaag gtcgaagcag ctaaagaaca tttacatgaa
     7921 attaattcag catgtcaaat tactgcgatc ccagcgccga ttactgctga ccttattgac
     7981 gaatatcagt ttaccctttg tttagactgt cttgataatt atcaagcacg ggacctatta
     8041 aacaaattag caatcatcaa aaattttgat tatctgtttg ctagttgtgc aggtacctat
     8101 gggaatgtaa tggcaatttc gccgcaaaat catccttgct tgaactgtct ttttcctaat
     8161 atcaatgaat taaaacaaaa cgattgtgat ttaattgggg ttaatactgc tttaattcct
     8221 attgtagcgg gactacaggt atctttagcg cttcattatc tggttgataa aacacaggtt
     8281 aattttaatg aattgatcac tgttgacaat tggtcaatgc aatttagtaa gtttgctatt
     8341 aataaaaatt gccattgtcc cgcctgtgct aagcctagca gtattttttt agaagaagaa
     8401 tcagcaccag aattacatat gttatgtggg gaaaatgcat attatacagt caaagagaaa
     8461 cctattaatt ttggcagact taaagaattt ttggctaaaa aagagctctt aattaacgca
     8521 aatcgattgt ttcttcattt taaatgggaa aatcgtccag taagtatatt taagaatggt
     8581 aagattgtta tgtatgactt acctacttcg gcgattgccc agaaacagtt tgagtcatta
     8641 aatattttaa tgaaagaaga cctattatga aaaaaatcgc aattttaacg gttagcgata
     8701 gtcgaacatt agatagcgat acttctggaa aattaattgt tatgaagatg gctaatgcgg
     8761 gcttatcagt agttgatcgg gtaatcgtta atgatgatat tgtcaatatt caaactgcct
     8821 accttcaact agaacaacaa gctattgata tcatcattac taatggtgga acaggagttg
     8881 ctcagcgtga tgttactatt ccggctatcc gtccactcct caaacgccta attcctggtt
     8941 ttggggaagc gtttcgccag atatcttttg atgaaattgg tactcgggcc cttgcatcac
     9001 aagccctagc cggatttaat taccgcaacc agctcaccta ttgtttacca ggttcccaga
     9061 atgcctgtca aacagctcta aataaactaa ttttgccaga atatgaacat ttattatttg
     9121 aaagtagttc tcaacgaaag gaagttcatc accatgctca ctagaaggat tccaatttca
     9181 gttgccgagg cccagaaaaa gattaacgaa attcccctta aaacagctgc agatacaatc
     9241 ccgttatcag aagctaacca ccgcgtttta gctaaagatg ttcatgccaa ttatgattat
     9301 cctcattttc gacgggctgg aatggatggt tatgccattt tagccagcga tgatcatgat
     9361 tttcctcgcg aatttaacgt ccgaggagag attcaagctg gagcaacttg ggatcaacca
     9421 ttacaatcgg gggatgcggt ccgaattatg actggtgcat atgtcccttc agatgtagga
     9481 aaagtaattc gaattgaaaa aacgcggcct gctaaagatg aaaacaaggt tcaaattatt
     9541 acgactgaaa gcaagactaa cattacggaa gctggtactg atgtaaaaag cggtgatatc
     9601 gttttagcaa aagaccagga aataaatccc ggtggtctag cagtcttaac agcttttggt
     9661 gttcaagaag tagcagttta taaaaaacca cgaattgcaa ttatcgccac tggaactgaa
     9721 ttattagggc ctaatgatac aattgaaccg ggaaagatct ttaatagtaa tggcattatg
     9781 ctaaaaaatc ttgtagaaga aactggtggg attgttgatt ttgaaaccca attaccagat
     9841 gatgctgaac ttatcaagcg gactcttgaa gaacaaatgg caacgcatga aattgtaatt
     9901 actgatggtg gtgtttcagt cggtgatttt gattttattg gagatgaagc acgtaaagct
     9961 gatgaattgc tttttaataa gattaagcaa cgaccaggaa gcgttacgac tgcctttgtt
    10021 caaaataata cgttaataat ggccctttct ggaaatccag gagcttgttt tactggcttt
    10081 tacctttaca tggaaccgct gattcgccgt tatcaacacc aagcaagccg aattaagcaa
    10141 gtgcgggcaa tattagcagc cccatataat aaaacaaatg ggttcgaccg ttaccttcgt
    10201 tgtacttatg aattcaaaga gaatcaattt tatatttatc caaatggaat caaccgatct
    10261 ggctcattag ctaatctcca gacgacgacc tgtttagcac tgattccgca tagtacgact
    10321 ccaatgaaag tcggaacgga gactgacgca tggctattac ccttcaaata atcggtcata
    10381 agaaaagcgg gaagactctt atcactacga ctttaatcga aagactcgca aaagaaggat
    10441 atcaggtagc tgctcttaaa catgatgccc ataatgctac aatggatgtg ccaactactg
    10501 acagtgctag aatgagtaac gctggagcta agcaggttat cttacaatct gccaccgaat
    10561 ttttctttca tcaaaaaagt aatgttccac ctttaacgga aatggttgag ttgttaagtg
    10621 ccgaaaatga ttttgtcttg attgaaggtc ataaggaagc cactcaatat ccgcaaattt
    10681 tattattaaa gccaggcgaa gatcctgcta atattgtccc tactcctcct cttaaaacgg
    10741 gtagtatctt taggggaaca accgctgact tactaggaaa agatgcaatt gtaagttggt
    10801 gctataacta cttaaaacaa ataaaggggg atgcaggatg attggattag tatatgctgg
    10861 tggtaaatct acccgttttg ggaaagataa agctacttat catattccag gattaccagt
    10921 taccaatata gagctagcag tcgagaaatt aacacccttt tgtcagcaga tcgttgtttg
    10981 tgctaatgaa ataaatcgag cacatatatt aaagttggtt ggtcaaggac cggctgtgca
    11041 gattatctgt gatattcccc cttatgatca tcatggtccc ctctcagcaa ttattgcttg
    11101 tactagtcat ttttcaactc ttcaggacta tttaactctg gctgttgatt atccttatat
    11161 cacaaaagat tcacttgctg ttcttgctcg tacgtccaac tcttatattg caacaagtca
    11221 gcatagtcat tattcattag ctcatttttc aattagcaat gaacaagtta ctacttgggt
    11281 cgctgataat gatgactggc gattacgtag tttcatcact aataaatgcg tctgtcaccc
    11341 cctcgtatat cggtcaagtg ccgaattttc aaatttaaac tatcgtgagg ttgatttaaa
    11401 tgaaaagtaa agattcaatg acaaatcctg attttcaaaa actcatttcc cttgtcttaa
    11461 acgacttaac aatcagacga acaatgttag aaaatcggga acaagaagta agccaacaaa
    11521 tgagttcgct ggaaaaagat gctgaattag agcaactgga tgaccaaatt caacagattc
    11581 aagctgattt tgatcattac cgtgaattcc aggatccaaa atttgagttt agtgcaacca
    11641 agtattttca aggaccatcg atgggtttac caggacatcc ttaaaactta gatggcagga
    11701 ctaggagaag tgaagctttt cttagccctg ccttttagtt tgcctttcat tgcttctaac
    11761 taaagaaagc gttattatat aaaataggaa cattatgatg acaattgggg aggaagcaga
    11821 tcgtgcttga aacagctaat tggatacaaa aatattttaa tcaatcacca gatgcaatct
    11881 tcttatttaa aaatgatgat cttttagtta gtaatgagcc agcccagcgg ttagttactg
    11941 tgcttaattt aaatgtcaat tacctattac aaattggaaa aaacgcttgg tcacaactag
    12001 aaaatgatga ctgtgcgtca tgtctgatta aaaagcggtt aaagggagct gtagttccga
    12061 taacatttca ttccaatgct actcatccct ttcacttttc aatggtttat cgtcctcttg
    12121 atgataaaga aaatgtcttt gccttgaatc ttgaaaatcg tgagcaacag caacgccttt
    12181 cgcagattga agagcatcga attctcaatc aatacgtaaa tgaagcacgc gaaaaggaac
    12241 ggcaaaaaat ctcacaagat cttcacgata gtgttgcaca gggaatctac gccgcaataa
    12301 tgggcattca aagattagca acggtgcaaa atcaaagaaa tactgagcaa tttcaatcaa
    12361 tgagtgctgc aatcgaaaag cagttacaaa cgactcttaa agagattaaa gggatcgcac
    12421 ttgatattcg cccctcggtg ctcgataatt ttggcttaat tccggcaatc aaagctttgg
    12481 cgaaacgtct tcaaaatagc accggaatca cgattgatgt tatagccctt acctctgctg
    12541 aaaaattaca aaaaaatatc caaaacgttc tttaccgcat tacacaagag gcaattaata
    12601 acgcaattaa acatgctcat tcaacagaaa taagtattat tgttacggat cacgatagtt
    12661 accttcagtt agagattctt gataatggaa ttggatttga tattgatcag catagtggat
    12721 ttaatgggca ttcacttgga ttaatgaata tgaatgaacg cgttaaggca tataacgggg
    12781 cctttacaat tacatcaaaa attaataagg gaacgacagt caaggtaaag tttccctata
    12841 ataatgcttt aaataaggat atggtgagaa caaatggata acgttttagt tgcagacgac
    12901 cacgcaattg ttcgctcagg aatttcatac ttagttgatc ttcaaccgaa ttttacggtg
    12961 gttgatggga cagcgagtgg aactgataca tatattcgag ttgaacaagg cggaattgat
    13021 atcttaatta tggatttaag tatgccccct ggcgaaaatg gcctaattac tactcgtcga
    13081 atccatgata agtttccaaa agttaaaatt atcattctct cgatgcatga agaacaggaa
    13141 tatatcaaca aggcaatggc aaatggcgca atgtcttata ttttgaagag ttcaccagat
    13201 agcgaaattg ttaatgccct aaaacatgtt ataaatggcg agaaatacct tgatgcaaat
    13261 atcattgtta gtaagacaga tattagagaa ataaatgcat ctggtaacac cttaaaacta
    13321 aagggctaca atagtctttc aaaaagagag aaagaagtct ttccgcttat tgctttaggg
    13381 tattcaaata aagaaatctc ccaaaagatg tttatttcaa caaagacagt agaagcacat
    13441 aaagcaaata tttcgcgcaa acttcactta catggacggg ttgaactagt acaatatgct
    13501 attcatcacc atttaattga cctttaactg ggcggggatt cttaattagg aagaatcccc
    13561 gattttattt acttcgatgt ttttctacaa taaaagaaac acgattaaag gagtggattt
    13621 ctaatggctg caaacctcag tcgagatgat gagttacagg gaattcttag tgatgttgct
    13681 cgcaaacgtt ttattaacag tcgccaggtt aatcccgttt ccaacctatt tttaacaact
    13741 aaatacgccg ttgaaaagca atatatttct ggagcagtta ttgacgagtc atttagctca
    13801 acattagcag agataaattt aaaaaatgct gttttaactg atcgcggtcg taataagctt
    13861 gaacaacttc tcactcaatc aacaaaggag aattaattaa gatggatatt caagataagc
    13921 taaaacgaga ttacgaaaat aaatcaatct atactgcagg cttttacgcc gacccagaca
    13981 atgaacttgc aaatcgcaaa aaattatttg atgccttaaa atcattagtc gagaatcaag
    14041 cagcaacaac tccgtttgct ttacaaatca tgcttacaaa tggtgaaatt aatgtaatgc
    14101 ccctcggact tgttgacctt gaagaactta aaaaatatga aagtgaacaa cgatccaagc
    14161 atggattaga tgagcataat gatgatattc ctctcctaat ccaatatgcc cctcatgcag
    14221 agaaaaaaga agtagttaaa aaaagaatag gcaccattca agatcttttt acaaacttta
    14281 acgagcaaat tgaaaaaata tggcaaactg ttaaagaatt tatgcaggat aattttgcgt
    14341 tattaacgac tatcgaaaag gatttgattg cagatagtca gaatgtgatg catgagtatc
    14401 aaattacttt ttctaagatg actgaggcgg aacgaaaaga aaagctggga tttagtgttc
    14461 cagaaaatga agttaaccaa ttctgccgct acatggctga tatgcatgaa gttcaagcaa
    14521 tcgtattatc tgctggggcc tttgttaatc atgaacttct tggtaaaaat tcctttactg
    14581 aaatgataag cgataatatt cgacggagta ccctcttttg ggttcttgat aataccttct
    14641 acgaaattta ttactatttc tacatgagca atgacaatga taagcttcat aaacgactta
    14701 aacatcaacg agaagctctc atcgttaata tgcgtaatga tgcttttcac cgtgcacaag
    14761 aatttactga gaagcaagca aaaaatgttg attttaatga atatttcagt gatatcttca
    14821 tcccagttgc tgaacaaata attgctgaag tgaataaatt taaggactga tactgtgaat
    14881 ttaacaccag atgaacggtt ggtagatgca ttaacaacca ttatttatca atatcctcca
    14941 atggttcgcg aaatgattaa cttgagtact ggtgaagaag aacgtcggct aaggttgtca
    15001 ctttttgaga cttttagtta tttcaacgaa aaagagctca caattgatca aatcacagct
    15061 gctcaactac cagaactatt ggcattatca actcatttga attctccttc ttttcaacca
    15121 aataacctaa ctcctgggga attcgctagc caaaaagcat attcatatgt tgcgagctat
    15181 ttaatgaatc gctttgtccg ttcactaagt actgtgggta atcctccaca agtaattgag
    15241 gagttgacaa ctgacgctgg ggatgtgatg cttgcacaga ttcaacgact acagtttaac
    15301 tataatcagc aatttaaggt agctgactat ttagcagatg ctaaagcacg atggggatta
    15361 cttggagcaa tgactgcaaa acaaagtgcc gtccttagcg gagcaggaaa tgaagttgtt
    15421 tcactggcgg gacagattgg tcaagcctta ggtactgcta gttatattac acatgagttt
    15481 caacagctta gtaatgatcc tgattcgttt gtaaagatga taacgagtgg tcagtatccc
    15541 ctagcgcttt tattcgctcg ccaacaaaat ccacaatggt ttagtaattt tttcgcttca
    15601 gatcatcgtc cttcacaagc gatgtttaag caagcccatc aattagcact tgaacgaatt
    15661 gatgatgtca aacaactaat tgctgatatc ttctcccagt taatccttga tattaaagtg
    15721 ttaccggctg gtcaagttca ggataaattg cttagcctag ctgaagaact aaaaaaggaa
    15781 taatttaaaa ctgaaaatgg agattaagga agaactatcc gtacaatacc ctttagggtt
    15841 gacactttaa ataataaaag tgccaattct agg
//
