LOCUS       c00009_CABHNQ0..       14021 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CABHNQ010000009.1 Bifidobacterium pseudocatenulatum isolate
            Bifidobacterium_pseudocatenulatum_SS_Bg39 genome assembly, contig:
            14, whole genome shotgun sequence.
ACCESSION   CABHNQ010000009
VERSION     CABHNQ010000009
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 18:48:31
            Original ID  :: CABHNQ010000009.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 30585
            Orig. end    :: 44606
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14021
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[40585:43171](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12586
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..14021
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14021
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             2109..4007
                     /NRPS_PKS="Domain: AMP-binding (54-497). E-value: 6.2e-92.
                     Score: 300.0. Matches aSDomain:
                     nrpspksdomains_ctg9_29_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     285.6; E-value: 9.6e-87)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_29"
                     /sec_met_domain="AMP-binding (E-value: 6.3e-92, bitscore:
                     299.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHRSRTHHKQKYAEITQKPRERERFMLTEYTAPGESVEVGDDESI
                     YSLLTGRIARTGEDTVIAERKTAPGQWTKVTTGEFHKDVIAAAKGLIAFGIAKGDAVTI
                     FSATRYEWGVLDFALAAIGAVNVPIYDTDSAAQAERILNDSDVKLAIADNRERFDRLDS
                     VIDRCPSLKHILMLDSNAMGALEGLGVTVSDEELEARIDSVHADDLATIVYTSGSTGAP
                     KGAELSHRNFISITRAGSLALHEIVLEDHPRLLLFLPLAHCFARFIQYASIASDDGVVG
                     YLPDTKTLLPDLRSFEPTYLLGVPRVFEKVYNAASRKAGMGWKGRLFLKAAEAARDWSR
                     MQQAGEKPTMKQTAEHLSYEASVYRTVRGALGPRIRYVACGGAPLDVSLAHFFNGIGLP
                     MIQGYGMTETAAPFAANRVTDNVIGTVGQPAPGSSVRISDDGELQVKGPNVFRGYHNLP
                     EKTAEAFTEDGWLKTGDLASIDDEGRITITGRKKDIIITAGGKNVSPIPMEQEIVKCPI
                     VEHAVVVGDNRPFIGALVTLDPEGLAAWLPSVGLSADTPLDRIATVAAVHDEIQKYVDK
                     ANATVSRAESVRKFVVLDTQFTQENKCLTPSLKVVRPAVNRVFAQVIDQQLYSGKR"
     aSDomain        2271..3599
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg9_29_AMP-binding.1"
                     /evalue="6.20E-92"
                     /label="ctg9_29_AMP-binding.1"
                     /locus_tag="ctg9_29"
                     /protein_end="497"
                     /protein_start="54"
                     /score="300.0"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RTGEDTVIAERKTAPGQWTKVTTGEFHKDVIAAAKGLIAFGIAKG
                     DAVTIFSATRYEWGVLDFALAAIGAVNVPIYDTDSAAQAERILNDSDVKLAIADNRERF
                     DRLDSVIDRCPSLKHILMLDSNAMGALEGLGVTVSDEELEARIDSVHADDLATIVYTSG
                     STGAPKGAELSHRNFISITRAGSLALHEIVLEDHPRLLLFLPLAHCFARFIQYASIASD
                     DGVVGYLPDTKTLLPDLRSFEPTYLLGVPRVFEKVYNAASRKAGMGWKGRLFLKAAEAA
                     RDWSRMQQAGEKPTMKQTAEHLSYEASVYRTVRGALGPRIRYVACGGAPLDVSLAHFFN
                     GIGLPMIQGYGMTETAAPFAANRVTDNVIGTVGQPAPGSSVRISDDGELQVKGPNVFRG
                     YHNLPEKTAEAFTEDGWLKTGDLASIDDEGRITITGRKKDIIIT"
     aSModule        2271..3599
                     /domains="nrpspksdomains_ctg9_29_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg9_29"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2736..2795
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg9_29_0001"
                     /evalue="8.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg9_29"
                     /protein_end="229"
                     /protein_start="209"
                     /score="21.4"
                     /tool="antismash"
                     /translation="ATIVYTSGSTGAPKGAELSH"
     CDS_motif       3429..3503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg9_29_0002"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg9_29"
                     /protein_end="465"
                     /protein_start="440"
                     /score="33.7"
                     /tool="antismash"
                     /translation="GELQVKGPNVFRGYHNLPEKTAEAF"
     CDS             complement(4136..5650)
                     /locus_tag="ctg9_30"
                     /transl_table=11
                     /translation="MAMENPFEGKEIWFGVGSQDLYGEEALRQVAQQTGEMVDFLNNTG
                     KIPAKIVLKPTLKSSDGVKAFMTEASATPNVIGVITWCHTFSPAKMWIRGLEVLTKPLL
                     QLATQHHKEIPWETIDMDFMNLNQAAHGDREFGYMVSRLGIPRKIVVGHYTDPEVAEKV
                     GTWARACAGWNASQNMKVMRWGDNMRNVAVTEGDKTEAERVFGASINTWAVNELVAAYD
                     KVKDDQVKALIEDYKAKYDVAPELLDSRYDELFIAAKEECAMVNMMRENGCTAGVDNFE
                     DLGALPQLPGVGPQRFPSEYGWGFSAEGDWKTAVLVRIGAVMGYGLEGGASLMEDYSYN
                     FTAGNELDMGSHMLEVSPSIGTIAKPKLDIYPLGIGGKSDPVRLVFSGKPGDAVVVSMA
                     DERERFRLLMDEVSIVEPQGSLKNLPCARAVWKPKPDLKTAVQCWIAAGGSHHTCMTTS
                     VGREAWEDFARIAGVELAVIDENTTARQFEKELQLSEMYHRLNNRH"
     CDS             complement(5733..6425)
                     /locus_tag="ctg9_31"
                     /transl_table=11
                     /translation="MATLADYGPEVRAEVKQVREVVATLHEQLIKWNLVVWTAGNVSQR
                     LHTANLMVIKPSGLRYEYLTPSSMVVCDLDGNVVDGSEAPSSDTASHAYIYRHMPDVYG
                     VVHTHSTYATAWAATGQNIPCGLTMMGDEFGGPVPVGPFRLIGSEAIGEGVVETLKKYP
                     KSPAVLMQNHGPFTIGKDAEGAVKAAAMTEEVARTMWAAKQIGDIIPIAQEDIDKLNDR
                     YTNVYGQH"
     CDS             complement(6449..8086)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210:glycerol kinase (Score: 135.9; E-value: 2.6e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_32"
                     /transl_table=11
                     /translation="MVQEQELDDQVALTAEKIRAGKTSLGIEFGSTRIKAVLIDDTYHT
                     IAAGDYGWASHLEDGLWSYSQEEIWTGLQTAYAALAKDVENAYGEKLTRVGRIGFSAMM
                     HGYLAFDKNGELLVPFRTWQNTNTSEAHEKLSELFQYNIPERWSIAHLYQAVLNDEEHI
                     GKVDFFTTLAGYVHWKLTGKKVLGVGDASGMFPIDPTTHTYETEFIEKFNAIPEVAAQP
                     WKLADLLPEPLVAGTPAGTLTEEGAKLLDPTGTLQPGIAFAPPEGDAGTGMVATNSVRV
                     RTGNVSAGTSIFAMVVLEHKLERLHPEVDLVTTPAGDLAGMSHANNFTSDLNAWVGLFG
                     QFAAAIGTPVDAGALYGTLFRAAIADDVDSNCGGLINYPFRSGEFLAGLPEGRPLFARG
                     PEARMSLGNFMRAQLFSAFSPVKIGMDVMTKDEGVAVDSLVGHGGIFTTPKVAQKILAA
                     AFDTPIKVMSTAAEGGAWGMAVLADYLWHADQPLDEFLDARVFADAASTTENPDENDVA
                     GFEEFFDRFRKGLPIEHTAIANIPLETK"
     CDS             complement(8307..9425)
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 222; E-value: 2e-67)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg9_33"
                     /transl_table=11
                     /translation="MAGRRNAGKKRPSMFEVAKYAGVSHQTVSRVINHSPDVSDVTREK
                     VQKAINELGYRPSNSARALASRRSRTIGLIAGGQRFYGPISAISSIESMARQHGLFMTV
                     SMVHEALCTQAEFDDLCRTFDEMNVDAYIFLTPTDVMFSAACRTQVMQPRVIVTSTHGS
                     IGVQDGLRLMSSADRRRVSVVGVDQWSAMADVMRLVVEYGHRSVLYFAGPKDWRDAATR
                     LVAWNKLCAANSVNSVTVQCETWESSEAYGKMNHILDNVGRAGGGLPTCMVCANDGQAV
                     GVARALHEHGVRIPQDVSLVGFDDMPAMDNMFPPLTTVRPGFEQLGVAAMREAVYLLGE
                     GDENSFAASRHGVGLVSAELIKRSSIGPVQRR"
     CDS             complement(9644..9799)
                     /locus_tag="ctg9_34"
                     /transl_table=11
                     /translation="MDAVLIGINVVHIQSAADNDEKIEFVFMSMSAFIVCNVRTLFMIF
                     LLCCIF"
     CDS             complement(9775..9960)
                     /locus_tag="ctg9_35"
                     /transl_table=11
                     /translation="MQNNRLMVLSFLQTKAMLIVEPPSSGSSSGSSNCCSSKIHFILIF
                     LSKIVSRRQWTQCSLA"
     CDS             10001..12586
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_36"
                     /sec_met_domain="LANC_like (E-value: 2e-19, bitscore: 60.9,
                     seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="micKC (E-value: 1.9e-140, bitscore: 460.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1e-08, bitscore: 26.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGKYIDFIGQPGLHYTPATPDINSREYAINPPNNWIKITDDYWS
                     YVAPAQHILPIQGWKLHVSSTLGNAQQVLSIVSSYCFENSISFKFTTTPRKLLLKNSKS
                     GNRAACGKFITIYPNETDLKHTITYLDALLVEYRSAPYILSDMRYKQGPIFYRYGGFQK
                     IQDPTGTLCVIKPDGSYVEDARVPYYRVPNWVTTPAFLIQDQRAQESGEQVPDFHGFEV
                     RKALHFSTGGGIYQVSKDSTDYIMKEGRPHCGLDASGHDAIARIKHEAQILRALEKLNG
                     VPHIIDEFDAWEHHYIVETFEQSMTLGRWLALNYPFSRSKSAEATAQYLNTLQIIVKNL
                     TQTLLQLHKEGYAHGDIQPHNIIVNPDTGQGVFIDFETAVLHDYDHSLSIGTPGYLDSV
                     NDPLNTRDWTGLYRSIRGALLPISTIEMLGSNKPKEMQQWIASEYGLEGSTILNTILHA
                     AQSEGIDASANQTALVASKQYRPTSIQGIVKDLRDSLSAAIDWSSPSLIHGDPLQYEHR
                     LNRYSLAYGGAGVWKTLLDFTPDHPALRAKLPEWLNTIDSNLPSCIEGYFSYGLFTGIA
                     GIIELAIRAKQRHIAQHIVHMLAEHIASSDSKGITSISIESGYAGIILALTYYHEHYHD
                     NISLKIAEECIERCAAVLTEPNNTLIYDSSATPTGLLYGWSGVSLACMRMYDITSSQKY
                     LDLADTCLQQDLQRLNITDGICNLATDDSRLMPYFSLGSAGVSLTMQRRTQYPSTRNHQ
                     QEHLASIHNALIARPCAHAGLFKGEAGLIGTLLTLSGHDQTSRQIALDYASLFLIQKSD
                     DESLYAPGDFSYRFSDDLATGTIGWIYALSGNILSIFPGFPLSERRWPQ"
     CDS             12583..12708
                     /locus_tag="ctg9_37"
                     /transl_table=11
                     /translation="MNEILQMQALYVEETERTAGASSVSVAFSCKKFSSISLLIC"
     CDS             12905..13309
                     /locus_tag="ctg9_38"
                     /transl_table=11
                     /translation="VGFFSSNGTIDIQYCIILFLLFVSNSLLNALTNYCSQLLSQRFVL
                     KLQLLVGRHIFNLSTSELARYSNGELASRTISDITVAKNIVSPQVLSLPGTILLILCST
                     ITIIIIDPLLSLTTIFLLALILIISLISGK"
     CDS             complement(13793..14020)
                     /locus_tag="ctg9_39"
                     /transl_table=11
                     /translation="DKGHKMFANEFSSKLFDGLCPILDLPFGRGDDSDGSQSEGCFPRA
                     RRPSYGNKPVLGKLKRHSLKYSRGVWGILD"
ORIGIN
        1 tgtcgcgcaa cgttcctgca aaaaggtggc tttgcgccgc cacgatggcg attcccctcg
       61 taagggattc gatggaaaga tcgttgattt ggtaccgttg cgtcgagctg tttcctgcat
      121 ttccggacag cagccacata catccttcat atccggaaag atttccggag agcagttcga
      181 cggcggtaga tttgccggat ccggacggac cgacgatggc ggtcacctgc ccacgccgcg
      241 cagtgaaaga gacgtcatgc aatgcgacga ccgaaccatc gtcatctttc gacatgcctg
      301 tttttccagc accaaccaca ccggactttt tccggggttt tctagtttcc ccagtttccg
      361 catccgccgt cgcagccgta tccgcagcca cactcacagc cgctgcagcg tccgcgccca
      421 cgtccgcata tcggaacgac acgtcatcaa agcacacgtc cacaccgtta tcggaagcac
      481 cgaattccgg catttcctgc accccatgcg caggaatcgg cgtatcaagc aatgcgaaaa
      541 tacgcttggt tgaagtcatg ccgttcatcg caacatggaa gaacgacccc aattggcgca
      601 gcggaatgaa gaaatccgcg gaaagaagca ctatcagcag cacgccggca agcggcaata
      661 cggcaccgtt cgcatactgc cagatcgcca cgcccacgcc ggccgcagca cccccgtacg
      721 caacgatgtc catggcggtg agcgagcgca gctgaatttg cagaacattc atggtcatta
      781 cacggaattg ttccgcctgc tcgttcattt tcttggcggc atgcgcatcc gcatcaaaag
      841 ttttcagcgt ttcaagacct tgtacattgt caagaaacac agatcccatg tcggtgtatt
      901 ttccccaata ttttttgaat actcgagcta cgcgcattgc gaccatgcca acaatcaata
      961 caatcaatgg cgcgcataca agcaatgtaa cagccgtcgg catattaatc ggcgcaacta
     1021 taaaaaataa cgttaccggc gcgagaatcg cataaaacag ttgcggtagg aataattcga
     1081 agaagctttg gatttgttcg atgccttcac cggcagattg caccacgtcg gcagtactga
     1141 tatgttgcga atatgatggt ccgatcgcaa gcattttatt gaataattgt tcacgtaacg
     1201 cgagtttgac acgctcggcc gcttccgcgc cgaaataggc cgcggtgcgc atcatcagaa
     1261 aacgcagcac cgcgcagacc acgatcgcca gtacgcatcc aacgtacgtt tccgcgctga
     1321 atccgccgta gccaaagccg acgaacaggc gggaaatcag gccactatca cccatggaga
     1381 acatggggtc gaatgccgat tccaccatgg caagcgctgg tgaaagcatg agcaccatcg
     1441 tcaccacgaa cacgacgttg gacagcagtc cgatccattg gcagagcact ttcgccgcaa
     1501 ccaaccgtcc cacgccggga gcgagggaaa acagccgttt gtcaaacatc gaaatccttt
     1561 ccttcacatt cacgcggttc aatttgcgcg cccgcatcac catgtctctc gattcagcct
     1621 atccacccgg aaacagaaac gtcaagagct catcgcacat agcaatcgca aacgcatctc
     1681 cagcaaaaat acgcgaacca agcacacgtg cggcccatgc cacacgacca gcgaaacggc
     1741 gaaagagtaa aaggctggat gttcgccgtt gagcaggcag ccctctgacg caaggggtaa
     1801 attgcgtcac tcgtgagtgt actcgataaa aatcgctcgc accaccattt cttcgtattt
     1861 ctctggtttt acggtcattt cgggaatata tggaaagcat ggcagctccc ccgcaaccgt
     1921 tacgtcaagc ctttttccga acggatatag cgcgacatca aacacttgat ttttgacgga
     1981 atatcaccat ttgtcagttc atacaaagtt gatggaatat ttcttgtcgc ttctcacaat
     2041 gcagacttac ggccccgtaa cttagaatgt gcgaggtgcg caaggggtag gaaacgcgga
     2101 cacacggttt gcatcgctcc cgcacgcatc acaagcagaa atacgcggaa ataacgcaaa
     2161 aaccgcgaga aagagaacgc ttcatgctca ccgagtacac cgcaccgggc gaatccgtcg
     2221 aggtcggcga cgacgaatcc atctattccc tgcttaccgg acgcatcgcg cgcactggcg
     2281 aggataccgt gatcgcggaa cgcaaaaccg cccccggcca atggacgaag gtcactaccg
     2341 gcgaatttca caaggatgtg atcgccgccg ccaaaggtct tatcgcgttc ggcatcgcca
     2401 agggcgacgc cgtcaccatc ttctccgcca cccgctacga gtggggtgta ctcgatttcg
     2461 cactggccgc aatcggcgcg gtcaatgtgc cgatctacga cactgattcc gcagcgcaag
     2521 ccgagcgcat cctcaacgat tcggatgtga aactggctat cgccgacaat cgcgagcgct
     2581 tcgaccgtct cgactccgta atcgaccgct gcccgtctct caagcacatt ctgatgctcg
     2641 attccaacgc catgggcgcg ttggaaggct tgggcgtcac cgtgtccgac gaggagctgg
     2701 aagcgcgcat cgattcggtg catgcagacg atctggctac catcgtgtac acgtctggtt
     2761 cgacgggagc tccaaagggt gccgagctat cgcaccgcaa tttcatatcg atcacgcgtg
     2821 cgggcagtct ggcgttgcat gagatcgttc tcgaagatca tccgcgactg ctcctcttcc
     2881 tgccgcttgc ccactgtttc gcacggttca ttcagtacgc gtcgattgct tccgacgacg
     2941 gtgtggtcgg ctatctgccg gatacaaaga cgctactgcc cgatttgcgt tccttcgaac
     3001 cgacatatct gctgggcgtg ccacgagtgt ttgagaaggt gtataacgca gcctcccgca
     3061 aggccggtat gggttggaag ggacgtctgt tcctcaaggc tgccgaggcc gcacgcgatt
     3121 ggtcgcgcat gcagcaggct ggtgagaagc cgaccatgaa gcagaccgcc gagcatctct
     3181 cgtatgaggc ttccgtatac cgtaccgtgc gtggcgccct cggcccgcgc atccgctacg
     3241 tggcatgcgg tggcgctcct ctggacgtgt ctctggcgca tttcttcaac ggtatcggcc
     3301 tgccgatgat tcagggttac ggtatgacgg aaaccgctgc gccgttcgca gccaaccgcg
     3361 tcaccgacaa tgtgatcggc actgttggtc aaccggctcc gggatcgtct gtacgcattt
     3421 ccgatgatgg cgaactacag gtcaagggac caaacgtgtt cagaggctac cataatctgc
     3481 ctgagaagac ggcggaagcg ttcaccgagg atggatggct gaaaacaggc gatttggcgt
     3541 cgattgacga cgagggacgc attacgatca ctggccgtaa gaaggacatc atcatcactg
     3601 ccggcggtaa gaacgtctcc ccgattccga tggaacagga gatcgtgaaa tgtccgattg
     3661 tggagcatgc ggtagttgtt ggcgacaatc gcccgttcat cggtgcgctg gtcacgctgg
     3721 atccggaggg attggcagct tggctgccgt ccgtgggatt gtccgcagac actccgctcg
     3781 accgcatcgc gaccgtcgct gccgttcacg atgagattca gaagtatgtg gacaaggcga
     3841 acgcgacggt ttcgcgcgcc gaatccgtac gaaagttcgt agtgctagat acccagttca
     3901 cgcaggaaaa caagtgcctg accccgtcgc tgaaagtggt gcgtccggca gtgaaccgcg
     3961 tgttcgcgca ggtgatcgat cagcagctgt actccggcaa gcgctgaatg gggcgatcgt
     4021 agagaaaaat acgggccgtc gttgggattt cccagcggcg gcccgtattt ttttattgca
     4081 tcttcgatga cgctcgcagc gtcatcgaag ataacgtgcg caacgctccg ttatttcagt
     4141 gacggttgtt gagacggtgg tacatttcgc tcagctgcag ttccttctcg aactggcggg
     4201 cggtggtgtt ctcgtcgatg acggcgagct cgacaccggc gatacgggcg aagtcctccc
     4261 aagcctcacg accgacggag gtggtcatgc aggtgtggtg ggagccgccg gccgcgatcc
     4321 agcactgcac ggcggtcttg aggtccggct tcggcttcca gacagcacgt gcgcacggca
     4381 ggttcttgag ggaaccctgc ggctcgacga tggagacctc gtccatgagc agacggaaac
     4441 gttcacgctc gtcagccatg gaaaccacga cggcgtcgcc aggcttgcca gagaacacca
     4501 gacgcaccgg atcggacttg ccgccgatgc ccagcgggta gatgtccagc ttgggcttgg
     4561 cgatggtacc gatggacggg gagacttcca gcatgtggga acccatgtcg agctcgttgc
     4621 cggcggtgaa gttgtaggag tagtcctcca tcagtgatgc gccaccttca aggccgtagc
     4681 ccatcacggc gccgatgcgc accagcacgg cggtcttcca gtcgccttcg gcggagaagc
     4741 cccagccgta ctcggacggg aatcgctgcg ggccgacacc cggcagctgc ggcagggcac
     4801 caaggtcttc gaagttgtca acgccggcgg tgcagccgtt ttcgcgcatc atgttgacca
     4861 tggcgcactc ttccttggca gcgatgaaga gctcgtcgta gcgggagtcg agcagctcgg
     4921 gagccacgtc gtacttggcc ttgtagtcct cgatgagggc cttgacctga tcgtccttga
     4981 ccttgtcgta ggcagcgacg agttcgttga cggcccaggt gttgatggag gcgccgaaca
     5041 cgcgttcggc ctcggtcttg tcgccctcgg tgacggcgac gttgcgcatg ttgtcgcccc
     5101 aacgcatgac cttcatgttc tgggatgcgt tccagccggc gcaggcgcgt gcccaggtgc
     5161 cgaccttttc ggcgacttcc ggatcggtgt agtgtccgac gacgatcttg cgcggaatgc
     5221 cgaggcggga caccatgtag ccgaactcac ggtcgccgtg ggcggcctgg ttgaggttca
     5281 tgaagtccat gtcgatggtc tcccacggaa tctccttgtg gtgctgggtg gccagctgca
     5341 gcagcggctt ggtaagcact tcgaggccac ggatccacat cttggccggg gagaaggtgt
     5401 ggcaccaagt gatcacaccg atgacgttcg gggtggcgga ggcttcggtc atgaaggcct
     5461 tgacgccgtc ggaggacttc agggtgggct tgagcacgat cttggccggg atcttgccgg
     5521 tgttgttcag gaagtcgacc atttcgccgg tctgctgagc cacctggcgc aacgcttcct
     5581 cgccgtacag gtcctgcgaa ccgacgccga accagatttc cttaccttcg aacgggtttt
     5641 ccattgccat cgttgtttcc ttacttcatt gtgttggata gaggtatgtg ttatgtgaca
     5701 gagcggaacc atgcagaatc cgctccgtca agtcagtgct gtccgtagac gttggtgtaa
     5761 cggtcgttaa gcttgtcgat gtcttcctgg gcaatcggga tgatgtcgcc gatctgcttg
     5821 gcggcccaca tggtgcgggc gacctcttcg gtcatagcgg ccgccttgac ggcgccttca
     5881 gcatccttgc cgatggtgaa cgggccatgg ttctgcatga gcacggccgg ggacttcgga
     5941 tatttcttca gggtttccac cacgccttcg ccgatggctt cggagccgat gagacggaag
     6001 ggacctaccg gcaccggacc gccgaattcg tcacccatca tggtcagacc gcaaggaatg
     6061 ttctgaccgg tggccgccca tgcggtggcg taggtggagt gggtgtgcac tacaccgtag
     6121 acgtcgggca tgtggcggta gatgtaggcg tgggaggcgg tgtcggagct cggggcttcg
     6181 gaaccatcca ccacgttgcc gtcgaggtcg caaacgacca tcgagctcgg ggtgaggtac
     6241 tcgtaacgca ggccggaggg cttgatgacc atcaggttgg cggtgtgcag acgctgggag
     6301 acgttgccgg cggtccacac cacgaggttc cacttgatga gctgctcgtg cagggtggcc
     6361 acgacttcgc gcacctgctt gacttcggcg cgtacttccg ggccgtaatc agccaaagtt
     6421 gccatgatat gtttcctttc tacaaaactt acttggtttc caagggaata tttgcgattg
     6481 ccgtgtgctc aatcggcagt cccttgcgga agcgatcgaa gaattcctcg aatcctgcaa
     6541 cgtcgttttc gtccggattt tccgtggtgg aagctgcatc tgcgaatacg cgagcgtcaa
     6601 ggaattcgtc gagcggctga tcggcgtgcc acaggtagtc ggcgagcacg gccatgcccc
     6661 atgcgccacc ttcggctgca gtagacatca ccttgatcgg cgtatcgaat gcggctgcga
     6721 ggatcttctg ggcaaccttc ggggtggtga agatgccacc gtgaccaacg agggagtcaa
     6781 cggcaacgcc ttcgtctttg gtcatcacgt ccatgccgat cttcaccggg gagaaggcgc
     6841 tgaacagctg ggcgcgcatg aagttgccga ggctcatgcg ggcttccgga ccgcgtgcga
     6901 acagcggacg gccttcgggg agtcctgcaa ggaattcgcc ggaacggaac gggtagttga
     6961 tgagtccacc gcagttggaa tcgacgtcgt ctgcgatggc ggcgcggaac agcgtgccat
     7021 acagggcgcc ggcgtcgacc ggagtgccga tcgcggctgc gaattggccg aacaggccaa
     7081 cccatgcgtt gaggtcggac gtgaagttgt tggcgtggct catgcctgca agatcgccag
     7141 ccggagtggt gacgaggtcg acttccggat gcaggcgttc cagcttgtgt tcgagcacga
     7201 ccatggcgaa gatggaggtg ccggcggaaa cgttaccggt gcgcacacgc acggagttgg
     7261 tggccaccat gccggtgccc gcgtcaccct ccggcggggc gaaggcaatg cccggctgca
     7321 gcgtgccggt cgggtcgagc agcttggcgc cctcctcggt cagcgttcca gcaggagtgc
     7381 cggcgaccag cggctccggc agcaggtcgg cgagtttcca cggctgggct gcgacttccg
     7441 gaatcgcgtt gaacttctcg atgaattcgg tttcgtaggt gtgcgtggtc gggtcgatcg
     7501 ggaacatacc ggatgcgtcg ccaacgccga gcaccttctt gccggtgagc ttccagtgca
     7561 cgtaaccggc gagggtggtg aagaaatcga ccttgccaat gtgctcttcg tcgttgagca
     7621 cggcctggta caggtgtgcg atggaccagc gttccggaat gttgtactgg aacagttcgg
     7681 aaagcttctc gtgtgcttcg gaagtgttgg tgttctgcca agtgcggaac ggcaccagca
     7741 gttcgccgtt cttatcgaag gcgagatagc cgtgcatcat ggcggagaag ccgatgcgtc
     7801 ccacgcgggt gagcttttcg ccgtaggcgt tttcgacatc tttggcgagc gccgcgtatg
     7861 cggtctgcag cccggtccag atttcttcct gcgaatagct ccacaggcca tcctcaagat
     7921 ggctggccca gccataatcg ccggcggcga tcgtgtgata ggtgtcgtcg atgagtacgg
     7981 ccttgattcg ggtggagccg aattcgatgc ctaggctcgt cttaccggca cggatcttct
     8041 cggcggtcaa tgcgacttgg tcgtcaagtt cctgctcctg caccatagtg tcaaactcct
     8101 tgtgtccgag cgcctacgca accactctgt caaccgaatg ttagcgctca ctgttaacgc
     8161 tcactattct aaacgcaaat tacgaaccgc acaaactcgc gtgtcaaaga aacaatccgt
     8221 cagcgcaatc gtccgaaaca gcgaaccggt gccgagtccg cactcagcac cggttcacga
     8281 aatcacagga ggagaacagc cgaccatcaa cgtcgctgca cgggaccgat tgaactgcgc
     8341 ttgatcagtt ccgccgatac caaaccaacg ccatgccggg acgcggcgaa cgaattctcg
     8401 tcgccctccc ccaacagata caccgcctca cgcatcgcag ccacacccaa ctgctcgaaa
     8461 ccaggacgaa ccgtggtcag cggagggaac atgttgtcca tcgcaggcat gtcgtcgaat
     8521 ccgaccaagc tcacatcctg cggaatccgc acgccatgct catgcaatgc gcgtgccacc
     8581 ccaacagcct gaccatcgtt cgcgcacacc atgcaagttg gcaaaccgcc gccggcgcgg
     8641 ccgacgttgt cgagaatatg attcatcttg ccgtacgcct cggaggattc ccaggtctcg
     8701 cactgcaccg tcacggaatt gaccgaattg gccgcgcaca gcttgttcca tgccaccaat
     8761 ctcgtagccg catcacgcca atccttcgga ccggcgaaat acagtacgga acgatgcccg
     8821 tattccacga cgagacgcat cacgtcggcc atcgcggacc attggtccac gccgacgacg
     8881 gatacgcgac ggcgatcggc ggaagacatc aatcgcaaac catcctgcac gccgatactg
     8941 ccatgcgtgg aagtgacgat cacacgcggc tgcatgacct gcgtacggca agccgccgaa
     9001 aacatgacgt cagtcggcgt gaggaagata tacgcatcaa cgttcatctc atcgaacgta
     9061 cggcataggt cgtcgaactc agcctgcgta cacaaagcct cgtgcaccat gctcaccgtc
     9121 atgaacagac catgttgccg agccatcgat tctatcgacg aaatcgcgga aatcggtccg
     9181 taaaaccgtt gaccgccggc gatgagcccg atggtgcggg aacggcgcga ggcaagcgca
     9241 cgggcagagt tgctagggcg atagccaagt tcgttgatag ccttctgcac cttctcacgc
     9301 gtcacatcgg aaacgtccgg cgaatggttg atgacccggg atacggtctg atggctcact
     9361 cccgcatatt ttgccacttc gaacatcgaa ggacgttttt tgcctgcatt gcgcctgcct
     9421 gccatgcccc gtcgcctccc gcacacaact attggtacgt tcgcctattg tacacacact
     9481 tatggtgaac gctaacatca cacccttcaa cgacacacat acacaaaagt tgtacgtcat
     9541 cacttgtctt tgaacaatac catttataac attaataata gtttctttta agaaacattc
     9601 acaatgtaaa ccatgtcaat tctacgaaaa aattcaacaa taatcagaaa atacaacaga
     9661 gtaggaatat catgaataaa gtccttacat tacaaacaat gaaagcagac atggacataa
     9721 aaacaaactc tattttttca tcattgtcag cggcactttg tatatggacc acatttatgc
     9781 caatgagcac tgcgtccatt gccgtctgct aacgatttta cttaagaaga ttagtatgaa
     9841 gtggattttg gaactacaac aattactact acccgaagaa gagccagacg atggaggttc
     9901 gacaatcagc atcgccttcg tctgcaaaaa ggaaagcacc atcagcctgt tattttgcat
     9961 ggatagatga agcggcctgc ctataggaaa gagggaaacc atgaccggaa aatatataga
    10021 tttcattggt caacctgggt tgcattacac ccccgccacc ccggacatca acagtcgtga
    10081 gtatgccatc aacccgccca ataactggat taagatcaca gacgattact ggtcttacgt
    10141 ggcaccggca cagcatatac ttccaatcca agggtggaaa ttacatgtat catccacttt
    10201 aggcaatgct caacaggtgc tgtccattgt atcgtcatat tgtttcgaga acagcatttc
    10261 gtttaaattt acaacaaccc caaggaaact gttactcaag aattcaaaga gcggaaatcg
    10321 tgcggcatgc ggtaaattca tcaccatata tcccaatgaa actgacctta aacacactat
    10381 aacctatttg gatgcgcttc tcgtggagta tcgttccgca ccatacatcc tgagtgacat
    10441 gcgatacaaa caagggccga ttttttaccg ctatggtgga tttcagaaga ttcaggaccc
    10501 cacagggaca ttatgcgtca taaaacctga tggatcatat gtggaggatg ccagagttcc
    10561 ctattatcga gttcccaatt gggtaacaac gccagccttt cttattcagg atcaacgtgc
    10621 gcaggaatcc ggcgaacaag ttcctgattt ccatggattt gaggtacgaa aagctcttca
    10681 cttcagcaca ggcggaggca tatatcaagt ttcaaaagac agtaccgact acatcatgaa
    10741 agaaggacgt ccacattgcg gcttggacgc ctcaggtcat gatgccatag caagaatcaa
    10801 gcatgaggca caaatattaa gagctctcga aaagcttaac ggagtgcccc atattatcga
    10861 cgaatttgat gcctgggagc atcactatat cgtagaaacc tttgaacaat cgatgacact
    10921 gggccgatgg ctcgctttaa actatccttt cagccgaagc aagtccgctg aagcaactgc
    10981 gcagtatttg aacacattac aaattattgt caagaatctg acgcaaacac tcttgcaatt
    11041 acacaaagaa ggatatgcgc acggagatat tcaaccgcat aatattatcg ttaaccctga
    11101 taccggccaa ggggttttca ttgattttga gacagcagtc cttcacgact acgatcactc
    11161 tctttccatc ggcacacctg ggtatcttga ttcggtcaac gacccattga acacaagaga
    11221 ttggacaggc ctttaccgtt caattcgagg cgctttactt ccgataagca ctatcgaaat
    11281 gctgggatca aacaaaccta aagaaatgca acaatggatc gcctctgagt acggcctgga
    11341 aggaagcaca atccttaaca ctatccttca tgccgcacaa tcagaaggta tcgatgcatc
    11401 agcaaaccaa accgctctcg tcgcatccaa acaatatcgc cccaccagca tacagggaat
    11461 cgtcaaagat ttacgcgact cactctcagc tgcaatcgac tggtcttcac caagtctcat
    11521 tcatggagat ccacttcaat atgaacaccg attaaaccga tactccttgg cctacggcgg
    11581 agccggagtt tggaaaacac tccttgattt tacacccgat catccagcat tacgggcaaa
    11641 acttccagag tggctcaaca ctattgattc caatcttccc agctgtattg aaggatattt
    11701 ctcatatggt ttattcaccg ggatagccgg aataatcgaa cttgcaatca gagccaagca
    11761 acggcatatc gcgcaacata tcgttcacat gctcgcagag catatcgcat cttctgattc
    11821 caaaggcatt acttccatct ccatcgaatc gggatatgca ggaataattc ttgcccttac
    11881 gtactatcac gaacattatc acgataatat atccctcaaa atcgcagaag aatgcataga
    11941 acgatgcgct gcagtgctta cggagcccaa caataccctc atatacgact ccagcgcaac
    12001 accaacaggg ttgctatatg gctggtccgg tgtttccttg gcatgcatgc gtatgtacga
    12061 catcacttcg tcacaaaagt atctggacct tgccgataca tgccttcagc aagatctgca
    12121 acgtctgaac attaccgacg gcatatgcaa tctggcaacc gacgattctc gtttgatgcc
    12181 atatttctca cttgggagcg caggcgtgag ccttacaatg caacgcagaa cgcaatatcc
    12241 aagcacccga aatcatcaac aagagcatct agcatccata cataacgccc taatcgcgcg
    12301 cccctgcgca cacgccggtc tttttaaagg agaagccgga ctcattggca cacttcttac
    12361 cctttcaggc catgatcaaa cctccagaca gattgcgctc gattatgcat cgctttttct
    12421 cattcagaaa agcgatgacg aatcactgta tgcaccaggc gatttttcat atcgtttttc
    12481 agatgacctt gccaccggaa caataggctg gatttatgca ttgagcggta acatcttatc
    12541 cattttcccc ggattcccat tatcggaaag gaggtggcca caatgaacga gattctccaa
    12601 atgcaagctc tgtatgtcga agaaaccgaa cgcacagcag gcgcgtcctc cgtcagcgtt
    12661 gcattcagtt gcaaaaagtt tagttcgatt tctctcttga tctgctaaaa agaccaaatc
    12721 tagtggatga attcatattg aattcatcca ctatcataat gagcaatact ttgaggagaa
    12781 aactatgcca tccgtcctat acacccttct acgaggatca aaaatcctta tttttcttct
    12841 cattttcatc aatatttttt ccaatatatt aatatatgta caacctctat atatcggaag
    12901 cctcgtgggc tttttttcat cgaacggcac catcgatatt caatattgta ttattctgtt
    12961 tcttttattc gtcagcaact cactactcaa tgctttaacc aattattgca gccagctgct
    13021 ttcccagcgc tttgtactta agcttcaatt attagttgga cgacatattt ttaaccttag
    13081 tacttcagag ttggcaagat actccaacgg cgaactagca tcgagaacaa tctcagatat
    13141 cacagttgca aaaaacatcg tcagccctca agttctttcc ttacctggaa caatcttact
    13201 tatattgtgc tccacaatca ctatcatcat tattgacccc cttctttctt tgaccactat
    13261 cttcttactt gcattaatcc tgataatttc tcttatctca ggaaaataga tcgcaaaact
    13321 cactaagagc atccagcagc agtattccca tatcggtgag aatattcaga aatttgcttc
    13381 aagtgccatt tttgtaaaag caaacaactt ggaaacacaa tcaattagaa attatacttt
    13441 agcttcagaa agtttatttc attcatcaaa aaaactagcc cgtattctag cgattctgtc
    13501 acctatatct tcacttgcag cccaattctt tttgattatc gtcatattcc ttggaagcat
    13561 gagaatagct tccaacgacc tttcatatca atccttggcc gtaatcatta ctttcctact
    13621 ggtattggtt tctcccctag gaagcttcac ctcatccatc agcagcatcg cttccgcctt
    13681 agccgcattt gagcggctca agcctctcat cggcgacaat caggtcaccc ataccttaac
    13741 ggggaatctc gaattagcaa actcatgtca ccaacttcga tttgacaatg tttcagtcca
    13801 atattcccca tactcccctg ctgtatttca agctatgtct tttgagcttc ccgagaacgg
    13861 gcttgtttcc gtaactgggc cgtctggctc ggggaaaaca accctcgctc tgactgccat
    13921 cggaatcatc accccttccg aagggcaaat ccaatatggg acacaaacca tcgaacaact
    13981 tggaggaaaa ttcattcgcg aacatcttgt gtcccttgtc c
//
