GCA_902505535.1 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

CABWKH010000001 (original name was: CABWKH010000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	lanthipeptide-class-ii,RiPP-like	2,864	35,569	microvionin	RiPP	8%

CABWKH010000002 (original name was: CABWKH010000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	nucleoside	19,640	40,938

CABWKH010000012 (original name was: CABWKH010000012.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	NRPS-like	274,059	317,070	nosiheptide	RiPP:Thiopeptide	7%

CABWKH010000023 (original name was: CABWKH010000023.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	RiPP-like	32,337	42,729

Compact view

c00001_CABWKH0.. - Region 1 - RiPP-like,lanthipeptide-class-ii

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Location: 2,864 - 35,569 nt. (total: 32,706 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptide(s) for ctg1_13 - Putative Class II

ctg1_21 leader / core peptide: MVTLKNDNVVGDRGDGAAAA - VGDhaARELVDGLVDhaDhaGRWIPCDhaDhaG
allorf_011277_011396 leader / core peptide: VRPAFRVGEPGA - IDhbDhbDhbDhaRPDhbPADhbKDhaDhaDhaHCDhaRARICLQPQ
allorf_022146_022298 leader / core peptide: LGHAHTNRAHAAGG - GRPCRWHRAGLAVREDhbRMGDGRDhaACPRVAAGDhaCRRG
allorf_021961_022158 leader / core peptide: VHGPIRVIRRDGVTLGG - PQHAQHEQRGRGGKPVDQHAARFPQFQRDhaIAHIDhaYPRLRDhaAYIACVDhaV
allorf_022137_022208 leader / core peptide: MPPARTAAASGM - DhaDhbIGVCMAQYE
allorf_024255_024410 leader / core peptide: MGKLPPHGIFTASWMYGS - RRPNCLVPPIDhbMFGRLRWDhaGPGRRFGMDhbFLPCR

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Similar known gene clusters

Lanthipeptides

Core peptide predictions

ctg1_21 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 2241.2 Da

Molecular weight: 2242.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2260.5 Da N = 1; 2278.5 Da N = 2; 2296.6 Da N = 3; 2314.6 Da N = 4

allorf_011277_011396 - Class II

Cleavage pHMM score: -3.50

RODEO score: 0

Monoisotopic mass: 2746.5 Da

Molecular weight: 2748.1 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2766.1 Da N = 1; 2784.1 Da N = 2; 2802.2 Da N = 3; 2820.2 Da N = 4; 2838.2 Da N = 5; 2856.2 Da N = 6; 2874.2 Da N = 7; 2892.3 Da N = 8

allorf_022146_022298 - Class II

Cleavage pHMM score: -4.40

RODEO score: 0

Monoisotopic mass: 3853.9 Da

Molecular weight: 3856.4 Da

Number of bridges: 3

allorf_021961_022158 - Class II

Cleavage pHMM score: -3.70

RODEO score: 0

Monoisotopic mass: 5377.8 Da

Molecular weight: 5381.0 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 5399.0 Da N = 1; 5417.0 Da N = 2; 5435.1 Da N = 3

allorf_022137_022208 - Class II

Cleavage pHMM score: -7.30

RODEO score: 0

Monoisotopic mass: 1164.5 Da

Molecular weight: 1165.3 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1183.3 Da N = 1

allorf_024255_024410 - Class II

Cleavage pHMM score: -6.90

RODEO score: 0

Monoisotopic mass: 3820.0 Da

Molecular weight: 3822.6 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 3840.6 Da N = 1

c00002_CABWKH0.. - Region 1 - nucleoside

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Location: 19,640 - 40,938 nt. (total: 21,299 nt) Show pHMM detection rules used

nucleoside: (LipM or LipV or LipU or ToyB or TunD or pur6 or pur10 or nikJ or nikO or truD)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00011_CABWKH0.. - Region 1 - NRPS-like

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Location: 274,059 - 317,070 nt. (total: 43,012 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 274058 - 317070:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg11_266

Search NORINE for peptide: strict or relaxed

AMP-binding (14..381): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DfftIGiIYK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

c00012_CABWKH0.. - Region 1 - RiPP-like

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Location: 32,337 - 42,729 nt. (total: 10,393 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

No matches found.