LOCUS       c00201_CADBNU0..       13674 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CADBNU010000201.1 Bacillus coagulans isolate RUG14133 genome
            assembly, contig: RUG14133_asm_201, whole genome shotgun sequence.
ACCESSION   CADBNU010000201
VERSION     CADBNU010000201
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 02:30:25
            Original ID  :: CADBNU010000201.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13674
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13674
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[200:3674]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      201..3674
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13674
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13674
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             complement(3..143)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg201_1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.6e-12, bitscore:
                     38.5, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFKLTEEHEMIRKMVRDFAINEVGPTAAERDEEERFDREIFDKM
                     GE"
     CDS             complement(201..1358)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg201_2"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5e-55, bitscore:
                     176.2, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.7e-31, bitscore:
                     98.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.5e-38, bitscore:
                     121.2, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESILSNTKQDNLASEEQQMLMAMVRDFVNNEVVPFVPNMEKGEF
                     PRHLIKKIGELGLMGIPIPTKYGGAGMDFMSYILTIYEISKVSPALGVILSVHTSVGTN
                     PILFFGTEEQKQKFVPKLATGQYLGAFCLTEPSAGSDASSLQTRATKDGNEYIINGSKI
                     FITNGGEADVYIVFAKTNSKAGSKGVSAFIVEKGTPGLVIGKDEKKMGLKGSRTVQLTF
                     DHMRVPATNLLGEEGDGYKIALANLDAGRIGIAAQSLGIAEGAFEQALAYAKNREQFGK
                     PIIVNQGVGFKLADMATRIEAAKRLVYHAAGLKNQGKSCAKESSMAKMFASDTAMYVAT
                     EAIQIHGGYGYTKEYDVERYFRDAKVTQIYEGTNEIQKIVIARHL"
     CDS             complement(1450..2301)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg201_3"
                     /sec_met_domain="HCDH (E-value: 1.2e-38, bitscore: 122.2,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 7.1e-71, bitscore: 228.2,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIEKIMVVGAGQMGSGIAQVCATSGFEVVLYDIQEEAVSKGLAN
                     IYNLLSRQVGKGKLSEGERKEIINRIQQSTSLQDARDCQFVIEAAVENIDVKKDIFKQL
                     DEMTRPETILATNTSSLPITEIAAVTNRPEKVIGMHFMNPVPVMKLIEVIRGLATSDET
                     YEIVNKLGEKLNKVPIEVNDFPGFIANRILLPMINEAIYALYEGVATKEAIDDIMKLGM
                     NHPMGPLQLADFIGLDTCLYIMETLHEGLGDDKYRPCPLLRKYVNAGWLGKKTGRGFYV
                     YQ"
     CDS             complement(2487..3674)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg201_4"
                     /sec_met_domain="Thiolase_N (E-value: 9.6e-94, bitscore:
                     303.9, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 1.7e-47, bitscore:
                     150.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKTVILEGARTPFGKLNGGLSSLSASQLGGTAITEALKRADIGV
                     DTIDHVLLGTVLQGGQGQLPSRQAARNANIPWETKTETINKVCASGMRSVALADLLIRV
                     GEASTVVAGGMESMSNAPYVLKKARTGYRMGHSELVDLMIYDGLTCSFTGAHMGNYGNG
                     TAEELGITREEQDEWSYRSHQRALAAIESGKLGEEIVPVEIPQRKGEPMIVSVDEAPRK
                     DTSIEKLAKLKPAFDPKGTITAGNAPGVNDGACALVLMDEEKAEQEGRKPLAKILANES
                     IAVEAKDFPKTPGLVINKLLEKVGKTADDIDLFEINEAFAAVALASIKIAKLDPEKVNV
                     NGGAVALGHPIGASGARIILTLAYELKRRGGGLGIAAICSGGGQGDAILIEVPKQ"
     CDS             complement(3998..6112)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg201_5"
                     /sec_met_domain="Fer4_8 (E-value: 4.5e-15, bitscore: 46.4,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.7e-05, bitscore: 13.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQSLLAVNWIATIAVVAYAAYLFAYLIKTRVSYIKLGKKEEFDN
                     NIKARLKNIAVFVFGQKKLLKDKKSGAIHVMMFYGFILVQFGAIDFIIKGLIPGAHLPF
                     GPFYPGFTFFQELVTLMILVSVIWAFYRRYIEKLVRLKRGLKNGLVLIFIGTLMLTVLL
                     GNGMTMIWFGEDLSWSEPIASVIALAFGWMSEAASIVVFYIAWWIHLLVLLIFLVYIPQ
                     SKHAHLIAGPANVYLHRLDKPGKLKPIDFEDEDAESFGVGKINEFSQLSLIDLYACVEC
                     GRCTNMCPASGTGKMLSPMDLIVKMRDHLTNYGAAVTSQSPWVPQFMFNNTTGNQLAMQ
                     ASGLGAQESAATSIYDVSLIGDVITEEEIWACTTCRNCEDQCPVMNEHVEKIIDLRRYL
                     VMTEGKMRPDAQRALQNIEKQGNPWGLNKKDRENWRELRDDVYIPTVKELKKEEKEFEY
                     LLWVGSMGSYDNRSQKIALSFAKLLNEAGVSFAILGNKERNSGDTARRLGNEFLFQELA
                     EKNIKEFEKNGVEKIVTIDPHAYNIFKNEYPDFGFKAEVYHHTELLYKLVKEGKLVPKY
                     EVNETVTFHDSCYLGRYNDVYDPPREILKSIKGVKLVEMERNREDAMCCGAGGGLMWME
                     EETGHRINVARTEQALKTNATTISSGCPYCLTMLSDGTKAIEVEDSVNTYDVAEVLEKA
                     VFGEKMEIAS"
     CDS             6406..7626
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg201_6"
                     /sec_met_domain="PLDc_2 (E-value: 3.9e-26, bitscore: 82.0,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKGGPPLLYLFGTVIILLLLILIDYVFGRLYHLKHVKKHDFPVRH
                     SHITIFTSGPLLFEKMLADITEAKHHIHMLFYIFRNDEFGMTLLKLLEQKASEGVKVRI
                     LIDRIGSHRFPRKLMKKMSLKGVEMEYCHTPSFPFFFFHLQNRNHRKITVIDGKIGYLG
                     GFNVGNEYMDLHERLSPWRDCHVRFTGEGVWDLQKQFMTDWTEATWRGIELTEKELYYP
                     DLPRGNVQHQFFAFEGDCWEDKVSEMISYAKKSVIIGSPYFIPSKKAFGAILDAIKRGV
                     EIILIVPEMSDHLFIQEASYRFLRKLIRFNCCSVYRYRNGFYHAKIFIIDDHICSIGTA
                     NFDNRSFYFNHELNSLFKDPDMVNEMLDIAKIDLSKSTKLTANMLQHRNLSGVLKEWVA
                     ILLSPLL"
     CDS             complement(7861..9543)
                     /locus_tag="ctg201_7"
                     /transl_table=11
                     /translation="MNIAQAVEQTIKDEIKQAVLKSGLAEEALIPEIILETPREKAHGD
                     YSTNIAMQLARVAKKAPRQIAESVIEHFAKEKVHVEKIEIAGPGFINFFMDNSYLTELI
                     PNILKAGDDYGRTNFGQNKKIQVEFVSANPTGDLHLGHARGAAVGDTLCNILDAAGFDV
                     TREYYINDAGNQINNLALSIEVRYFEALGLEKEMPEDGYRGKDIIEIGKQLAEEYGDKF
                     VHVSEEERFEFFRQYGLKAELDKLKKDLEDFRVTFDVWFSETSLYKDGKVEEALDVLRE
                     KGQVFEKDGAIWLKTSAYGDDKDRVLRKSDGSYTYFMPDIAYHKNKFERGFETVINIWG
                     ADHHGYIPRMKAAMEALGFDPKALEVEIIQMVQLYKDGEKMKMSKRTGKAVTMRDLVEE
                     VGLDATRYFFAMRSSDTHLDFDLDLAVSQSNENPVYYAQYAHARICSILRQSEEVGMNI
                     EKIAGEDMDLALIGEEKEFDLLKKLGEFPQVIVEAAEKRAPHRITNYIHDLASAFHSFY
                     NAVKVVDTNNVELTKARLGLVKAVQITMKNALRLVGVSAPERM"
     CDS             complement(9540..9989)
                     /locus_tag="ctg201_8"
                     /transl_table=11
                     /translation="VPSNGTPVKISTTIKINRDGKREKYELIVFGQWFRKDQTTYLIYD
                     EYYEKKGKIHTVVKFTEGQIPQAQIIRKGSLNMMMYFKEKEIMGGTYKTEVGHFKIKTI
                     TKKLTFQQDDEAKTGTIKINYDFYMEGLEVGSYQLQFNFKEDKGK"
     CDS             10389..12356
                     /locus_tag="ctg201_9"
                     /transl_table=11
                     /translation="LYTFAKIAGPPPIEVPQSTIFFAADGTKIGETNHGQKRYWVELED
                     ISPHLVEATLAIEDQHFYTHFGFDYKRILGALVADIKALSKVQGASTISQQYARNLFLN
                     HEKTWSRKLKEAFYTIRLETNFSKDDILEGYLNTIYYGHGVYGIEAASQFYFNKKAKDL
                     NLSEAALLAGVPKGPSYFSPLVAYENAKNRQELILHEMAKQGRITKKEASIAATQPIEF
                     AAQEAATIPKIAPYFQDVVKSKLKEIGLDEQTINLGGLQIHTTLDPKMQKIAEEQFEKT
                     FPKNSQLQGALVAMDPKTGFVKALIGGRDYNASSFNRAIQSKRQPGSTIKPILYYAALE
                     KGFTPSSTFRSEETTFTFNDGRKPYTPHNFNHKYAEDDITLIQALALSDNVYAVKTHLY
                     LGMDTLAETTKRFGIKSPTAEIPSAALGTSNVRLIEMANAYSLLANGGKNIEPVFITKI
                     TDRNGNIVYEHKKERTQVLDKDVAFVTTHLMTGVFDDRLNDYTTVTGHNIRTKLTQIYA
                     GKSGTTDYDSWMIGFTPNLVTAVWVGYDKGKKMSRTDERQYAKNIWADFMEKSLDGTPV
                     RSFKPSSGVIGVYIDPETGLLASDKCLNRRFTYYVKGTEPTEYCDGKRPDELDLDKEPN
                     RKEIETDDTPWYKRWFDWLN"
     CDS             complement(12415..12924)
                     /locus_tag="ctg201_10"
                     /transl_table=11
                     /translation="LEEKKKTVHFNIIKNDPLDGHKGYNAGVLNLENVTPVFIDVAEQE
                     AFIDIGAMHAKSKVEKGLKFVPNIEELPNPKWYWLVWVTVERNENGPFYYGVTACDLAT
                     DREARRGYKIFPDHVNKMDKSLKGHFIVDHMDEPSKKTLAKFLQNQEGGLWKNSSAELK
                     KQLGVE"
ORIGIN
        1 agttcaccca ttttatcgaa aatttcacga tcaaaccgtt cttcttcatc ccgctctgct
       61 gcagtcggac caacttcatt tatggcaaaa tcacgaacca tttttcgaat catttcatgt
      121 tcttctgtta gtttaaaatt catatccttt tcccccttga ttggtgcaaa cttacaaata
      181 ttgttctata caatcattgt ttatagatgt cttgcgatca cgattttttg aatttcattt
      241 gttccttcat aaatttgagt taccttagca tctcggaaat accgttcaac atcgtattct
      301 tttgtatatc cgtaaccccc atgaatttga atggcttccg tcgccacata catcgccgtg
      361 tccgaagcaa acatttttgc catcgaagat tctttggcac aacttttccc ttgatttttc
      421 aatcccgctg catggtaaac taatcgttta gccgcttcaa ttctcgttgc catatccgct
      481 aatttaaagc caacaccttg attaacgata ataggtttac cgaactgttc acgatttttc
      541 gcatatgcta atgcctgttc aaaggcacct tctgcaattc ctaaactttg ggcagcaatg
      601 ccaattcttc cagcatcaag attggctaaa gcaattttat agccgtcccc ttcttcacca
      661 agaagattcg ttgctggtac acgcatatga tcaaaggtca gttgtacggt gcgtgatcct
      721 ttcaatccca ttttcttttc atccttaccg attacaagtc caggtgtacc tttttctacg
      781 ataaatgcag agacaccctt gcttccggct tttgaattcg tttttgcaaa aacaatgtaa
      841 acatcggcct ctccaccgtt cgtaataaaa atcttgcttc cgttaatgat atattcattc
      901 ccatcctttg ttgctctcgt ttggagagag gaagcatcag aaccagcact tggctctgtt
      961 aaacaaaagg cacctaaata ttgacctgta gcaagttttg gtacaaattt ttgcttttgt
     1021 tcctccgttc caaaaaataa gatgggattc gtccctaccg aagtatgcac ggataaaatg
     1081 acacctagag caggactgac tttagaaatt tcataaatcg ttaaaatata cgacataaaa
     1141 tccattcctg ctccaccgta cttagttggg atgggaatcc ccattaggcc aagttctcct
     1201 attttcttga ttaaatgacg tgggaattca cccttctcca tatttggaac gaatggtaca
     1261 acttcgttat tcacaaaatc acgtaccatc gccataagca tttgttgctc ttccgaagct
     1321 aagttatctt gtttagtgtt agaaagtatt gattccatat atataacctc ctttctttca
     1381 gaagattgca gaagcaatcc ttttgttaac gtttcctaaa aaatttcata aagaggaaag
     1441 attttttatc tattgatata cgtaaaaacc gcgacctgtc tttttaccta accagccagc
     1501 attaacgtat ttccgtaata acggacatgg tcgatattta tcatctccaa gaccttcatg
     1561 taaggtttcc ataatgtaaa gacatgtatc taaaccgata aagtccgcta attgaagtgg
     1621 tcccatcggg tgattcatac ctagtttcat aatgtcatca atggcttctt tcgttgccac
     1681 cccttcatat aaagcgtaaa tggcttcatt aatcatcggt agaagaatgc ggttggcaat
     1741 aaaaccagga aagtcattca cttcaattgg tactttattt aatttttcac ctaacttatt
     1801 gacgatttca tacgtttcat cactcgtcgc tagaccgcga atgacttcaa ttagtttcat
     1861 aacaggtact ggattcataa aatgcattcc aatgactttt tccggacgat tcgtcacagc
     1921 agcaatttcc gtaattggta aagaagatgt attggttgct agaatcgttt ctggtcttgt
     1981 catttcatca agctgtttaa aaatatcttt tttcacatct atgttttcca ctgcagcttc
     2041 tatcacaaac tggcaatcgc gagcatcttg taaacttgtg gactgttgaa ttcgattaat
     2101 gatttctttt cgttctcctt cactcaattt ccctttgcca acttgacgag aaagcaaatt
     2161 gtatatatta gcaagccctt tacttacagc ctcttcttga atatcatata aaacaacttc
     2221 aaaaccgctc gttgcacaaa cttgtgcgat tcctgatccc atttgtcctg caccgacaac
     2281 cataattttt tctatattca tgtgtaaaaa cctccttgag tttgctcgaa tacgaagtaa
     2341 tccttatgaa gtaattaaat ttaaatattt atagaaaaaa actatgaaat tcgtaaatgt
     2401 agagaaaggt aagttgtatt tctaaagaga aggcattatg ctggaaaaat ctatttgatt
     2461 ccacgtcttg cctatcacag gaacatttat tgttttggca cttcgattaa aatcgcatca
     2521 ccttgcccac cgcctgaaca aatagctgcg atacctagcc caccgcctct tctttttaat
     2581 tcataggcaa gtgttaaaat tattcttgca ccgcttgcgc cgatcggatg tccaagtgca
     2641 acagcaccac cgttcacatt gactttctct ggatcaagtt ttgcaatttt tattgaagct
     2701 aaagctactg ctgcaaaggc ctcatttatt tcaaacaagt caatgtcgtc agctgtctta
     2761 ccaacttttt ctaaaagttt attgataaca agtcccggtg ttttaggaaa atcttttgct
     2821 tctactgcga tcgattcatt agccaaaatt ttggccagtg gttttctacc ttcctgttct
     2881 gctttttctt catccattaa tacgagcgca catgcaccat cgttgacacc aggggcatta
     2941 ccagcagtaa tcgtaccttt cggatcaaag gctggtttta attttgcaag tttttcaatt
     3001 gatgtatctt ttcttggtgc ttcatctacc gaaactatca taggctctcc tttacgttgt
     3061 gggatttcaa ctggaacaat ttcttcaccg agcttcccag attcgatagc agcaagtgct
     3121 ctttgatgac tacgataaga ccattcatct tgttcctctc gagtaatacc taattcttct
     3181 gctgtaccgt ttccgtaatt ccccatatga gctccagtaa agctacacgt taatccgtca
     3241 taaatcataa gatcaaccag ctcgctatgc cccattcgat aacctgttct tgcctttttt
     3301 aaaacatacg gagcattgga catcgattcc attccaccgg caacaactgt gctcgcttca
     3361 cctacccgaa tgagtaaatc agctaaggca acactgcgca taccggatgc acaaacttta
     3421 ttaattgttt cagtttttgt ttcccatgga atattagcat tgcgcgcagc ttgccttgat
     3481 ggtaattgtc cttgccctcc ttgtaagacc gtacctaata gtacatgatc aatcgtgtct
     3541 actcctatat ccgcacgctt gagtgcctct gtaatggcag ttcctcctaa ttggctagca
     3601 gataaagaac ttaatccccc atttagtttg ccaaaaggtg ttcgtgcccc ttctaaaatg
     3661 accgtctttc ccataaccat cctccttaaa ttgttatcgc ttacattttg cgaaaatttt
     3721 ttaataaact tgttatcatt gctcttgatg gaatatttca cctatctaaa aaacattatt
     3781 tcttatatga ttttaattct gcttaaacta gatgactgga atgcttgtaa gtagaacata
     3841 gaagtagaag tgtggaaatc cctataatgc cttttgattg ttgactgaac gctcgctcgg
     3901 agttcgtggt gaaaaattgg gggatcatct tcccccatag ctctctaata ttagattaac
     3961 agattgttat aaattttcaa tattttttca aagattttta tgatgcaatt tccatttttt
     4021 caccgaaaac agctttttct aatacttcag cgacatcata cgtattcacg gaatcttcta
     4081 cttcaatggc cttcgtacca tcagatagca ttgttaagca atatggacaa cccgaactta
     4141 tcgttgtagc atttgttttt agtgcttgtt ctgtacgagc aacatttatc cgatgtcctg
     4201 tttcttcttc catccacatg agaccgccac cggcaccaca acacatggca tcctcgcgat
     4261 tacgctccat ctcaaccaac ttgactcctt tgatagattt taaaatttca cgcggtgggt
     4321 cgtatacatc attatatcta cctaaataac aagagtcatg gaaggtaacc gtttcgttca
     4381 cttcatattt cggtacgagt ttaccttctt ttacgagttt atataacaat tctgtatggt
     4441 ggtaaacttc agctttaaaa ccaaaatccg gatattcatt tttaaaaata ttgtaagcat
     4501 gagggtcaat ggttacgatt ttctccacgc catttttctc aaactctttt atgttctttt
     4561 cagcgagttc ttggaataaa aattcgtttc ctaagcgacg ggctgtatcg ccagagtttc
     4621 gttctttatt tcctaaaatg gcaaaggaaa cccctgcttc atttaataat tttgcaaaag
     4681 atagagcaat tttctggctg cgattatcat aggaacccat tgaaccaacc cagagcaaat
     4741 attcaaattc tttctcttct tttttcaatt ctttaactgt aggaatatac acatcatcac
     4801 gaagttcgcg ccagttttcg cgatcctttt tatttaagcc ccaaggatta ccttgttttt
     4861 caatattttg tagggcccgc tgtgcatcgg gtctcatttt cccttctgtc ataactaagt
     4921 aacgacgcaa atcaataatt ttttcaacat gttcgttcat aactggacac tggtcctcac
     4981 agtttcggca tgttgtacaa gcccagattt cttcttctgt aattacatca ccaattaagc
     5041 taacatcata gatcgaagtt gctgcagatt cctgtgcgcc tagaccgctt gcttgcatag
     5101 ccaattgatt acctgttgta ttattgaaca taaattgtgg tacccaaggt gactgggatg
     5161 taacagcggc accataattt gttaaatgat cgcgcatttt gacgattaaa tccatcggtg
     5221 aaagcatttt tccagtacct gatgcaggac acatatttgt acaacgtcca cactcaacac
     5281 acgcatacaa atcaattagt gatagctgtg aaaattcatt aattttacca acaccaaaag
     5341 attcagcatc ttcatcctca aaatcgattg gctttaattt acctggttta tcaagtctgt
     5401 gtaaatatac attcgctggt ccagcaatta agtgcgcatg cttagattgc gggatataca
     5461 ctaagaaaat taacagtaca agtaagtgaa tccaccaagc aatataaaat actacaatgc
     5521 tagctgcttc actcatccaa ccgaacgcta aagcgattac agaggcaatc ggttcagacc
     5581 aacttaaatc ttcaccaaac caaatcatgg tcattccgtt gccaagtaat accgttaaca
     5641 ttaatgttcc gataaaaata agcacgagtc cattttttaa accgcgtttt aaacgaacaa
     5701 gcttttcaat ataacggcga taaaatgccc atatgacaga gactaaaatc attaatgtga
     5761 caagctcttg gaaaaatgta aaccctggat aaaatggtcc gaatggtaaa tgagctccag
     5821 gaattaatcc tttaatgata aagtcaatag ctccgaattg tacaagaata aacccgtaaa
     5881 acatcattac gtgaatagcg ccactttttt tatctttcaa taattttttt tgtccgaaaa
     5941 caaaaactgc aatgtttttt aaacgcgctt taatattgtt gtcaaattct tcctttttcc
     6001 ctaatttaat atatgaaact cttgttttaa ttaggtatgc aaacagatat gctgcgtaag
     6061 caactacagc aatggttgca atccaattta cagctaacaa ggattgttcc atttgttctc
     6121 cccctttttt cgtgttctcc caatcctctt attaagcgct aatacaaata aaaagactgt
     6181 ccgattgaac tgtacccctt tcaccttact ttctattata taatgaatga gcattcagtc
     6241 aatgtatttg cttaattttt aaaagattcc catttacatg atatatacga catatatacg
     6301 acatttatct ccaaattcct tcaaaactaa atatttttat ttactattaa ggaggagcca
     6361 attgcataag aaaaagatca ttgggtaaac tattcttcta gtctggtgaa gggaggccct
     6421 cctttgctat atttattcgg tacggtcatt atattgttgt tattgatttt gatcgattat
     6481 gttttcggac gactttacca cttaaaacat gtgaaaaaac atgattttcc tgttcgccat
     6541 agtcatatta caatttttac gagcggtccc ttattgtttg aaaaaatgtt ggcagatatt
     6601 acagaggcta agcatcatat ccacatgctt ttttatatat ttagaaatga tgaatttggt
     6661 atgacattgt taaagctatt agaacaaaaa gcgagcgaag gagttaaagt ccgtatttta
     6721 attgatagga ttggcagcca tcggtttcca agaaaactca tgaagaaaat gagtttaaaa
     6781 ggtgtggaaa tggaatactg tcacacgcct agtttcccgt ttttcttttt tcatttgcaa
     6841 aatcggaatc atcgaaaaat aacagttatc gatggtaaga ttggatacct tggcggtttt
     6901 aatgttggca atgagtatat ggatcttcat gaaaggttga gcccatggcg cgattgccat
     6961 gttcgcttta caggtgaagg ggtatgggat ctgcaaaaac aattcatgac cgattggacc
     7021 gaagctactt ggcggggaat cgagctaaca gaaaaagaat tgtactatcc tgacttacca
     7081 agaggaaatg tccagcatca gttttttgcc tttgaaggag attgttggga agacaaagta
     7141 agtgaaatga tctcgtatgc aaaaaagagt gttattattg gttcacctta ttttattccg
     7201 agtaaaaagg catttggtgc catattagat gccatcaagc gcggtgtgga aatcatatta
     7261 attgtacctg aaatgagtga tcacttgttt attcaagagg cttcctaccg cttcttacga
     7321 aagctaattc gcttcaattg ttgttctgta tatcggtatc gtaatggatt ttatcatgca
     7381 aaaatcttta ttattgatga tcatatttgt tcgattggta cagcgaattt tgataaccgg
     7441 agcttttatt ttaaccatga gttaaatagt ttgtttaagg accctgacat ggtaaatgaa
     7501 atgctagata tcgccaaaat cgatttatca aagtccacaa aactaactgc aaatatgtta
     7561 caacatcgta acctaagtgg agttttgaag gagtgggttg caatattatt atcaccgttg
     7621 ttgtaacaat cacaagttaa tggaacttac acacgatttg aattcatttc attaaaatac
     7681 gatccttcta gatgaccttt attattgttt acagtacaga aatcttacat tagcaacctt
     7741 gcccgaaacc tgttacaaac aaagatctgc gggcaaggga taccttaaat catattcaaa
     7801 tgacaacgag taaattcaat tctatatacc aaaataggat gtcctattac cagtctatac
     7861 ttacattctt tccggtgcac taacaccaac taagcgtaat gcatttttca ttgtaatttg
     7921 tacagctttc actaatccta atcgagcttt tgttaattct acattgttgg tatctacgac
     7981 tttcactgca ttatagaagc tatggaaagc agatgctaag tcgtggatat aattcgtaat
     8041 ccggtgtggt gcacgttttt ctgctgcttc tacgattact tgtgggaact cacctaattt
     8101 tttcagcaaa tcgaattctt tttcttcacc aattaaagca agatccatat cctctcctgc
     8161 gattttctca atattcattc ccacttcttc actttgacgt aaaatgctac aaattcgcgc
     8221 atgggcatat tgtgcatagt acactgggtt ttcgttagat tgtgagacag ctaagtctaa
     8281 gtcaaagtct aaatgagtat ctgagcttct catagcaaag aagtaacgtg ttgcatctaa
     8341 accaacttct tcaacaaggt cacgcattgt aactgcttta ccagtccgct tactcatttt
     8401 cattttttcg ccgtctttat atagctgaac catttggata atttctactt ctaacgcttt
     8461 cggatcaaac ccaagggctt ccatcgctgc cttcattcgt ggaatgtaac catggtggtc
     8521 cgctccccaa atattaataa ccgtctcaaa accacgttca aacttatttt tatggtaggc
     8581 aatatcaggc atgaagtacg tatatgaacc atcagatttc cgtaataccc ggtctttatc
     8641 atcaccatag gcgcttgttt tgagccagat tgcaccatct ttttcaaata cttggccttt
     8701 ttcacgtaag acgtctaacg cttcttcgac tttcccatct ttataaagag aagtctcact
     8761 gaaccagaca tcaaatgtaa ctcggaaatc ctctaagtcc tttttcaact tgtccaattc
     8821 agcctttaaa ccatattgac ggaaaaattc aaatcgttct tcttcagaaa catggacaaa
     8881 tttatcgcca tattcttcag ctaattgttt cccaatttca ataatgtctt tcccgcgata
     8941 accatcttct ggcatttctt tctctagtcc aagggcttca aagtaacgga cttcaatcga
     9001 taaagctagg ttgttaattt gatttcctgc atcgtttata taatattcac gggtaacatc
     9061 aaaaccagcc gcatctaata tattacataa tgtatctcct accgctgctc cacgggcatg
     9121 acctaaatgt aaatctcctg tcgggttcgc tgaaacaaac tctacttgga tttttttatt
     9181 ttgaccaaaa tttgtacgac cgtaatcgtc accggctttc aatatatttg gtattaattc
     9241 cgttaaatag ctattgtcca taaaaaagtt tataaagcct ggaccagcaa tttcaatttt
     9301 ttcaacatgt actttttcct ttgcaaaatg ctcaataaca ctttctgcaa tttggcgtgg
     9361 cgcttttttg gcaactcgag ccaattgcat tgcaatattc gttgagtaat ctccatgggc
     9421 tttctctcta ggggtttcaa gtattatttc tggaattaat gcttcttcag ctaaaccaga
     9481 ctttaaaacc gcttgtttaa tttcgtcttt aattgtctgc tctacagcct gtgcaatgtt
     9541 catttaccct tatcctcctt aaagttaaat tgaagttgat aggagccgac ctcaagccct
     9601 tccatataaa aatcgtagtt gattttaatg gttcctgttt tcgcttcatc atcctgttga
     9661 aacgttaatt tttttgtgat tgttttgatt ttaaaatgac ctacttcagt tttatatgta
     9721 ccgcccatta tctccttttc tttaaaatac atcatcatat tcaatgagcc tttacgaata
     9781 atttgggctt gaggaatttg accttcagta aatttgacaa ctgtatgtat cttccctttt
     9841 ttttcataat attcatcgta aattaaatac gttgtttgat ctttcctaaa ccattgacca
     9901 aaaacgatta gttcgtattt ttctcttttc ccatctcggt taatttttat agtggtcgaa
     9961 attttgaccg gagtcccatt ggaaggcact tcctcacatc ctctacttgt acactatatt
    10021 aactatacca ttttagcgat ttcaatgtcg gatttcaatg tcaaaaattg tatctatatt
    10081 cgtatttacc atgttttcaa tgcgcttgaa actttctgtt tggtccttta aacctttaaa
    10141 aactttccca cttctttatg tttaaatatt ggcacctatt tccatactaa ctaatataag
    10201 gaaaatcctt cgaatggtaa acccttacga atccgtttta atttagaata cactcatttt
    10261 cacatagggg gaatgcatca atggagctga catctagtct tttttctaga cgtacgatca
    10321 aaatcgtcaa atttatctta acgatcacga gtctatgcgt cattatctta tttttaagtc
    10381 tagttggttt gtataccttt gcaaaaatcg ctggaccccc acctatagaa gttccacaat
    10441 ctaccatctt tttcgctgca gacggaacga agatcggtga aacaaatcat ggtcaaaaac
    10501 gctactgggt agaattagaa gatatttctc cacatttagt cgaagcaacc ctcgccattg
    10561 aggatcaaca tttttatact cactttggtt ttgactataa aaggatatta ggagcacttg
    10621 tagctgatat taaagcattg tcaaaagtac aaggggcaag caccatttcg caacagtatg
    10681 ctcgtaattt gtttttaaat catgaaaaaa catggtcacg aaagctaaaa gaggcatttt
    10741 atacaatccg gttagaaacg aatttttcca aggatgacat tttagaagga tatttaaata
    10801 cgatttatta cggccatggt gtttatggaa ttgaagctgc aagtcaattt tactttaata
    10861 aaaaggcaaa agatttaaat ttaagtgagg ctgcattgct tgcaggtgtg ccaaagggac
    10921 caagttattt ctcaccactt gttgcctatg aaaatgcaaa aaacagacaa gagcttattt
    10981 tacatgagat ggcgaaacaa ggacgaataa caaaaaagga agcgtcaatt gcagctaccc
    11041 aaccaattga atttgcagca caagaagccg cgacaatccc taaaatagct ccttattttc
    11101 aagatgttgt caaatcaaaa ttaaaagaaa ttggtttaga cgaacaaacc attaatcttg
    11161 gtgggttaca gattcataca acattagatc caaaaatgca aaaaatcgcg gaggaacaat
    11221 ttgaaaaaac attcccaaaa aactcccaat tacaaggagc tttagtcgca atggatccaa
    11281 aaactggatt tgtcaaagca ctaattgggg gacgggatta caatgcatcg agctttaacc
    11341 gagcaattca atctaaaaga caacccggtt caaccattaa gccgattctt tattatgcag
    11401 cccttgagaa aggatttaca ccttcatcga catttcggag tgaagaaacg acctttacgt
    11461 ttaatgatgg tcgaaaacct tatacacctc ataattttaa tcataaatat gcggaagatg
    11521 atattacact cattcaagca cttgccttat cagacaatgt atatgcagta aaaactcatt
    11581 tatatttagg tatggataca ctggcagaaa caacaaagcg atttggtatt aaatcaccaa
    11641 ctgcggaaat tccttccgct gctttaggta catcaaacgt tcgtttaatt gaaatggcaa
    11701 atgcttatag tttactggcc aatggtggaa aaaacattga accggtcttt ataacgaaaa
    11761 ttacagaccg caacggtaat attgtatatg aacataaaaa agaacgtact caagtattgg
    11821 ataaagatgt tgcttttgtg acaacccatt taatgacggg agtttttgat gatcggttaa
    11881 atgactatac aaccgtgaca gggcacaaca tccgtacaaa attaacacaa atatatgcag
    11941 gaaaatctgg tacaacagat tatgatagct ggatgattgg tttcacgcca aatcttgtta
    12001 ctgctgtatg ggttggctac gataaaggga aaaaaatgag tcgaaccgat gaaaggcagt
    12061 atgccaaaaa tatttgggcg gattttatgg aaaagtcact tgatggaacc ccagttcgat
    12121 cctttaaacc atcttcaggg gtaatcgggg tttatattga ccctgagact gggctactcg
    12181 cttcagataa atgtcttaac cgacgattca cttattatgt taaagggaca gaacccactg
    12241 aatattgtga tgggaaaaga ccagatgaac ttgacttaga caaggaacca aatcgaaagg
    12301 aaatagagac agatgataca ccttggtata aacgttggtt tgattggttg aattaaattg
    12361 atacaagata aatttttaaa aaagctcctt ggcattacac caaggagctt ttacttattc
    12421 cacacctaac tgttttttca gttcagcact tgaatttttc cataagccac cttcttgatt
    12481 ttgtaagaat tttgctagag tttttttcga aggttcgtcc atatggtcta cgataaaatg
    12541 tcctttcaat gatttatcca ttttatttac gtggtcaggg aaaatcttgt aaccacgtct
    12601 agcctcacga tccgttgcta aatcacaagc agttactccg taataaaacg gaccgttttc
    12661 attccgttcc accgttaccc aaacgagcca ataccatttc ggattcggca attcctcaat
    12721 attcggtaca aatttcaagc ctttttcaac tttacttttt gcatgcatcg ccccaatatc
    12781 aataaaagct tcttgttcag caacatcaat aaaaaccggt gtcacatttt ccaaattaag
    12841 aacgccagca ttatatcctt tatgaccatc taacgggtca tttttaataa tattgaaatg
    12901 aaccgttttc ttcttttctt ccaattttta cacctcttta tttgtatttt ctcttaaacc
    12961 gtttctaaaa aagatcgcct cagcaaaaga actctatatg tattctatat atatcatatt
    13021 acaattaagt aaatgattaa aagagtccgc catagaagag gatgatccat tctgtcagcc
    13081 gtggaacaag acctaaaatc ggaccgattg taacattata tagtggttta acaagcacta
    13141 aaactaaaaa gataagaacg ccgtagattt catattgact cagttttgcc cgcgtttcat
    13201 ttggtaataa gtcagaaacg attcgataac catctaatgg aggaatcgga attaaattaa
    13261 atacaaataa tagtacattt aaataaatga accaaaaaca caaactaaat ataaagttta
    13321 gtattggacc gtcaccaaga ccagcaatga caagtaaaat gaaaccaccg ataaatgcca
    13381 ttagtaaatt acttaatgga ccagctactg atgtcagtat tcctgctaac cgtggatttt
    13441 taaaattgaa acggttaacg ggtacaggtc gtgcccaacc aaatccgaat aaaagtaaaa
    13501 aaatcgttcc tagcgggtca agatgaacag aaggatttaa tgtcagtctc ccctgtcttt
    13561 ttgccgtcgg atcaccaaat ttgtatgcga cataggcatg agcaaattcg tgaacggtaa
    13621 aagcgatcat taacgagatg ataatatatg gcaaaatctg aatatcaaag gcta
//
