LOCUS       c00359_CADBNU0..       13274 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CADBNU010000359.1 Bacillus coagulans isolate RUG14133 genome
            assembly, contig: RUG14133_asm_359, whole genome shotgun sequence.
ACCESSION   CADBNU010000359
VERSION     CADBNU010000359
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 02:30:25
            Original ID  :: CADBNU010000359.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 6875
            Orig. end    :: 20149
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13274
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[16875:19418]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12543
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13274
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13274
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             662..1327
                     /locus_tag="ctg359_7"
                     /transl_table=11
                     /translation="MNDYSFIFHSFQHRKIQNKVEGERVLKNNQKPKYKQIIDAAVITI
                     AENGYHQCQVSKIAKQAGVADGTIYLYFKNKEDILISLFKEKMQQFIQNLSEIIAGKNT
                     AAEKLLLLVENHFRILSEDHALAIVTQLELRQTNKELRLKINDILKGYLQLIDNILEEG
                     IQNGEFAPALDIRLTRQMIFGTIDETATNWVMNDHKYDLVSLAPKIHQLLIHGCGNHH"
     CDS             1501..2274
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg359_8"
                     /sec_met_domain="ECH_1 (E-value: 2.9e-70, bitscore: 226.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFLNQEIVNKTAVLTINHPPANALAGAVISELDHMLNEIETNDE
                     VRVIVLKGEGRFFSAGADIKEFTSIDSEKNAAELATKGQKLMDRIENFPKPIIAAIHGA
                     ALGGGLELAMSCHIRIVSETAKLGLPELSLGIIPGFAGTQRLPKYVGTAKAAEMMLTAE
                     PVSGVDAVKIGLANIAVPEEKLLDEAMKLAKKIEMKSPSTIKAILNLLTYAKTEQFAKG
                     VEAEAKAFGEVFQTEDATEGINAFLEKRQPNFTGK"
     CDS             2322..3095
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 170.6;
                     E-value: 1.1e-52)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg359_9"
                     /sec_met_domain="ETF (E-value: 3.3e-53, bitscore: 170.6,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIYVLLKRTFDTEEKITITGGRIDEDGAEFIINPYDEYAVEEAI
                     QVRDEHGGEVTVITIGGEDAEKQLRTALAMGADKAVLINVEDDLEIKDQYTTAKILATY
                     LEDKDPDLILAGNVAIDNGTGQVGPRVADLLGIPYVTTITDLKIDGEKVTVVRDVEGDE
                     ETIETTLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLDEDDVEAKTKTIE
                     VFLPPQKSEGKILEGELADQVKELVSLLHNDAKVI"
     CDS             3130..4107
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 157.8;
                     E-value: 8.8e-49)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg359_10"
                     /sec_met_domain="ETF (E-value: 2.7e-49, bitscore: 157.8,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 6.4e-40, bitscore:
                     125.5, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRKVLVLAELKDNKLRNVSFEAIAAAKTIAEDGEVVSLLLGESV
                     ESLANELIQYGADRVVVVENDKLAQYNSDGYSQAVLAVIEQEDPEAIVFGHTALGKDLS
                     PKVASKLDSGLISDVVNVEVTGGNVVFTRPIYSGKAFEKKIVTNGLIFATVRPNNIAAL
                     EKDESRSGDVSKVDVDIKDLRTIIKEVVKKTSEGVDLSEAKVVVAGGRGLKSAENFKML
                     EELADVLGGAVGASRGACDAGYCDYSLQIGQTGKVVTPDLYIAIGISGAIQHLAGMSNS
                     KVIVAINKDPEANIFKVADYGIVGDLFEVVPQLTEEFKKLKVNA"
     CDS             4312..4626
                     /locus_tag="ctg359_11"
                     /transl_table=11
                     /translation="MAIVNATDQTFSEEIKSGLVLTDFWATWCGPCKMIAPVLEEIDAE
                     MGDKVKIVKLDVDENQETAAKYGVMSIPTLILFKDGEIVDKVVGYRPKEALEEVINNHL
                     "
     CDS             4739..6559
                     /locus_tag="ctg359_12"
                     /transl_table=11
                     /translation="MNNTQYGVSTLETKPKIKEKLALLPDQPGCYLMKDRQGTVIYVGK
                     AKVLKNRVRSYFTGSHNAKTQALVSEIEDFEYIITSSDVEALILENNLIKQYDPKYNVM
                     LKDDKTYPFIKLTSERHPRLIITRKVKKGDKAKYFGPYANVYAARETKRLLDKLYPLRK
                     CQTLPKQVCLYYHIGQCLAPCVFDVSQETYKKMTTEITKFLNGGYKEVKKDLTEKMIEA
                     SEKLDFERAKEYRDKITAIEMTMEKQKATMTDHIDRDVFGYAADKGWMCVQVFFVRQGK
                     LIERDVSMFPYYKDPEEEMLTFLGQFYDRPEHFKPKEILLPQNVDAELAHALLDVKIVQ
                     PKRGQKKEMVELANKNAKAALKEKFSLLERNEERTIKAIEKLGEQMNIYTPYRIEAFDN
                     SNIQGTNPVSAMVVFTNGMPDKKQYRKYKIKTVEGPDDYDSMREVIRRRYTRVLKENQP
                     LPDLILIDGGKGQIEAAKDVLENELGLDIPVAGLVKDDKHQTSNLLFGDPPEMVPLARN
                     SQEFYLLQRIQDEVHRFAITFHRQLRGKSMIQSILDEIPGVGQKRKQLLLKHFGSVKKM
                     QHASVEDFMKIGIPKNVAESIVQTLQNSEE"
     CDS             7146..8387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg359_13"
                     /sec_met_domain="AA_kinase (E-value: 4.3e-56, bitscore:
                     180.5, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGIIVQKFGGTSVATVEKILNVADRVLDERKRGNNVVVVVSAMGK
                     STDELISLAKQVSTKPSKRELDMLVTTGEQVTIALLAMALHEKGHDAVSMTGWQAGVET
                     EPIHGSARILNIDTDRINRAIREGKIVIVAGFQGITEDGEITTLGRGGSDTSAVALAAA
                     LGADRCDIYTDVTGVYTADPRYIPSARQLSTISYDEMLELANLGAGVLHPRSVEFAKNY
                     QIPLVVRSSTEKVEGTYVLEETIMEENLVVRGVAFEKDITKLTVYGLSNEIASLSSVFT
                     PLAKNNVNVDIIIQNASDQNLNTLSFSIKTDELQEALQVLEEHKESIGYDHIEYESGLA
                     KVSIVGSGMISNPGVAAQMFASLAEKDIFVKMVSTSEIKVSAVVNEDQMLKAAEILHDV
                     FGLSKVEQEVSVAK"
     CDS             complement(8506..8958)
                     /locus_tag="ctg359_14"
                     /transl_table=11
                     /translation="LSRKTVKEKINLTELTVPAFGYELIREDFIEEILGEDAPSILYWI
                     GKQIARKYPLFSFDEIQEFFRNAGWGNLDIISQKKSEIELQLTSDLVKHRILTRTNATF
                     QLEAGFLAEQIAQQKKVYAETFEHPKKKDGKVLFTVKWDDIPLIDL"
     CDS             9263..9874
                     /locus_tag="ctg359_15"
                     /transl_table=11
                     /translation="MAGNREFNNRRLHSLLGVLPIGIFLIVHLTINYQATKGAEAYNAA
                     AGLMENIPFLLFVETVVIYIPILFHAIYGVYIAFTAKPNNVRFSTFRNWMFVLQRITGV
                     ILIIFIAWHVWETRIAKALGAEVNFDMMANIVDNPAMLVFYIVGIVCATFHLSNGLWSF
                     FVSWGITVSPRSQRILTYVTMLVFVAVTFIGVRAILAFTV"
     CDS             10001..11755
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 292.3; E-value:
                     2.3e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg359_16"
                     /sec_met_domain="FAD_binding_2 (E-value: 7.1e-90, bitscore:
                     292.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-47,
                     bitscore: 151.4, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKGKIIVVGGGLAGLMATVKIAEAGVPVELFSLVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWKHFDDTVYGGDFLANQPPVKAMCEAAPGIIHLFDRMGVMFN
                     RTPEGLLDFRRFGGTLYHRTAFAGATTGQQLLYALDEQVRRHEVAGLVTKYEGWEFLGA
                     IIDDDQTCRGIVAQDLKSGEIKSFPADAVIMATGGLGIIFGKSTNSVINTGSAAAILYQ
                     QGAIYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPLYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEKFTGDDP
                     RKVPMKIFPAVHYSMGGLWVDYEQQTNIKGLFAAGECDYSQHGANRLGANSLLSAIYGG
                     MVAGPNAVKYIEGLEKSTDALPSSLFERYQRQEQQKWDDILKMDGTENAYVIHKELGEW
                     MTDNVTVVRYNDKLLKTDEKIQELMERWKNININDTSSWSNQGAQFTRQLQNMLHLARV
                     ITLGAYNRNESRGAHYKPEFPERNDEEWLKTTMASYDPATNAPKFEYEDVDVSLIKPRK
                     RDYTTTSK"
     CDS             11776..12543
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg359_17"
                     /sec_met_domain="Fer2_3 (E-value: 3.4e-33, bitscore: 104.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.4e-12, bitscore: 36.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.4e-05, bitscore: 13.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEQRKTVTFIIQRQDTPDSTPYEETFEIPYRPNMNVISALMEIQ
                     RNPVTKDGKKTSPVAWEMNCLEEVCGACSMVINGKPRQACSTMVDKLEHPIKLEPMRTF
                     PVVRDLVIDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPENKRQWAYELSKCMTCGVCL
                     EACPNVNDKSNFMGPAPLSQVRLFNSHPTGAMNKAERLNAIMGDGGLANCGNSQNCVQA
                     CPKGIPLTTSIAALNREATVQMFRNFFGSDYSY"
     CDS             12741..13115
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg359_18"
                     /sec_met_domain="HBT (E-value: 6.7e-17, bitscore: 52.1,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 4.2e-11, bitscore: 33.8,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFGHLNNTVPFVYFETARIEYIHYLGLYRQDLKEMRETIPVVANQ
                     QCDYIRQVYFDEELNIYVKINEVGNSSVDLHYLGVKGDDTVCFTGRGTIVNINKNSGKS
                     VPWTSEEREIFFKAMNVNVV"
     CDS             complement(13174..13272)
                     /locus_tag="ctg359_19"
                     /transl_table=11
                     /translation="MSEIILLQIHEPSLPSPARKRGDGYESSQYHM"
ORIGIN
        1 gaaatcaggt cattggaaac cgatgaaaca ctccctccag gtgaagtagg agaattagta
       61 attaaaggac cacaagtgat gaaaggttac tggaatcgtc ctgaggaaac ggcgaaaacc
      121 ctccgtgacg gttggttata tacaggagat ctaggttata tggatgaaaa aggatatttt
      181 tacattgtcg atcgcaaaaa agatatgatt atcgccagcg gatttaatat atatccaaga
      241 gagattgaag aggtgttata tgaacatccg gcggtccaag aggcagtggt agctggagtc
      301 cctgatccat atcgtggtga aaccgtaaaa gcttatattg tacttaaaga aggtcactca
      361 gttacggaaa aagagatgga caaatatgcc agaaaacatt tggctgccta taaagtacca
      421 agattatatg aattccgtga tgaattgcct aagacaaccg ttggcaaaat cttgcgtcgc
      481 caattagtag aagaggaacg gaaaaagata gaaaatcaag aaggggagaa aaaggcctaa
      541 tattatagat aaaaaatttt gcgaaaagga aacttctagg gcactttttt ttattcataa
      601 gttggacaag tgagataaga tggtatttga caaaaacttt caggtctttt aatataagaa
      661 tatgaatgat tattcattca tatttcattc tttccaacat agaaaaatac aaaataaagt
      721 cgaaggtgaa agagtattga aaaacaacca aaaaccaaaa tataagcaaa ttatcgatgc
      781 cgctgtaatc acaattgctg aaaatggata ccatcaatgt caagtttcaa agatcgcaaa
      841 acaagctgga gtagctgatg gtacgattta tttatatttc aaaaataaag aagatatatt
      901 aatatcttta tttaaagaaa aaatgcaaca atttattcaa aatttatctg aaattatagc
      961 aggaaaaaat acagctgcgg agaaattatt attattagta gaaaatcatt ttcgcatctt
     1021 atcagaagat catgctttag ctattgttac acaacttgaa ttacgtcaaa caaacaaaga
     1081 attacgtctg aaaattaacg atattttaaa agggtattta caactgattg ataacatttt
     1141 agaagaagga attcaaaatg gtgaatttgc cccagcatta gatatccgtt taacaagaca
     1201 aatgattttt ggaacgatag atgagacagc cactaattgg gtgatgaatg accataaata
     1261 tgatttagtc agcttagctc caaaaatcca tcagttactc attcatgggt gtgggaatca
     1321 ccattaatat ctgactattc ctatttatat ttctttctta aatattcaag aaaattattg
     1381 ctcaaaaatt tttatttaag acctatacaa ggttaaaaaa tgaattgttt agagacagag
     1441 tcttctctgt tttctaatag atgatcctat gaatctatta aatggaaaag gggatgggag
     1501 atggaatttt taaatcaaga aatcgtcaac aagacagctg tacttacaat aaaccaccct
     1561 cctgccaacg cattagcagg tgctgtcata tccgaactcg atcatatgtt aaatgagatc
     1621 gaaacaaatg atgaagttcg tgtcattgtc cttaaagggg aaggaagatt cttttctgcc
     1681 ggtgctgata ttaaagagtt tacaagcata gattcagaga agaacgctgc agagttggcc
     1741 actaaaggcc aaaaacttat ggaccgcatc gaaaattttc ctaaaccaat tatagcggcc
     1801 attcacggtg ccgcattagg tggcggatta gagcttgcca tgagttgtca tatacgcatt
     1861 gttagtgaaa cggcaaagct cggattacca gagctatcct taggaattat accaggattt
     1921 gccggaacac aaagactacc aaaatatgtt ggaaccgcaa aagcggctga aatgatgtta
     1981 actgcagaac cggtttcagg ggtagatgct gtgaaaatcg gtcttgccaa catcgctgtt
     2041 ccagaggaaa agctattgga tgaagcgatg aaattggcta agaaaattga aatgaaaagt
     2101 ccttcaacca ttaaagccat attaaatcta ttaacatatg caaagactga acaatttgcc
     2161 aaaggtgttg aggcagaagc gaaagcattt ggcgaggtat ttcaaacaga agatgctaca
     2221 gaagggatta acgctttttt agaaaaaaga cagccaaatt tcacggggaa ataaagtaag
     2281 tattttttat atacgaacaa acaatgtaag ggggatgttt gatgaacatt tacgttttat
     2341 tgaaaagaac ttttgacact gaagaaaaaa taacgattac aggtggcaga attgatgaag
     2401 acggcgctga gttcattatt aacccatatg atgaatatgc cgtagaagag gcaatccaag
     2461 tccgtgacga acatggtgga gaagtcacag ttataacaat cggtggagaa gatgccgaga
     2521 aacaactgcg tacagccctg gccatgggtg cagataaagc ggttttaata aatgtagaag
     2581 atgacttaga aataaaagat caatatacga ctgcaaaaat tttagcaaca taccttgagg
     2641 ataaagatcc ggatttaatt cttgcaggaa atgtagccat tgataatggt acaggacaag
     2701 tagggccaag agtggccgat ttattaggaa ttccttatgt gaccaccatt accgatttga
     2761 aaattgacgg agaaaaagtc actgttgtaa gagatgtgga aggtgacgaa gaaacaatcg
     2821 aaacaacact accactgctt gtgacagcac aacaagggtt aaatgaacca agatatccgt
     2881 cattaccggg gattatgaaa gcgaaaaaga aaccgttaga agaattagaa ttagatgatc
     2941 ttgatttaga tgaagatgac gttgaagcaa aaacgaaaac gatcgaagtc ttcctaccgc
     3001 cacaaaaatc cgagggtaaa attttagaag gtgaacttgc agatcaagtg aaagaattgg
     3061 tgtctttact tcataacgac gcaaaggtaa tttaaacttt aatacgttta cgaacaggag
     3121 ggtttttaaa tgggtagaaa agttttagta ttagcggagt taaaggataa taaattacgg
     3181 aatgtttcct ttgaagcaat tgcagcagca aaaaccattg ctgaagatgg tgaggtcgtt
     3241 agtttattat tgggagagtc ggtcgaatct ctagcaaacg aactgataca atatggtgcg
     3301 gatcgagtag ttgttgtgga aaatgataag ttagctcaat ataattcgga tggatattca
     3361 caagctgtac ttgccgtcat agagcaagaa gatccggaag ctattgtatt tggacataca
     3421 gcgttaggaa aagatttatc gccaaaagtt gcaagcaaat tggattccgg actaatttca
     3481 gatgtagtca atgttgaagt tacaggtgga aatgtggtct ttacaagacc tatttattct
     3541 ggtaaagctt ttgaaaagaa aattgtaacg aacggtctca tttttgcaac tgttcgtcca
     3601 aataatattg ctgcattaga aaaagacgag tctcgttccg gcgatgtttc aaaagtagat
     3661 gttgatatta aagatttgcg cacaatcatt aaagaggttg tgaagaaaac aagcgaaggt
     3721 gtggatctat cagaagcaaa agtggttgtt gctggtggac gtggattgaa aagtgccgaa
     3781 aacttcaaaa tgctggaaga attggcagat gttttaggag gagccgttgg tgcttcccgt
     3841 ggtgcgtgtg atgccgggta ctgcgactac tcactccaaa ttggtcaaac aggaaaagta
     3901 gtaacaccag acctttatat tgcaattgga atctcaggtg cgatccaaca tttagcggga
     3961 atgtccaatt caaaagtaat tgtagcaatt aataaagatc ctgaagctaa tattttcaaa
     4021 gttgctgatt acggtattgt tggtgattta tttgaagtgg tcccacaact tacagaagag
     4081 tttaaaaaat taaaagtaaa cgcttaaatt tctaagggta aagtgacaat ttgttacttt
     4141 accctttgat ttttttaaat tatatttaca aagtattctg ttattttttt cagtgatatg
     4201 atttaatggt tatttcagcc aatatagggt aaaatgatgt tgaaacaaat cattcgcaaa
     4261 tttgtggatc cagtgatata ctgtcgataa gaaattttaa ggagggttat tatggcaatt
     4321 gtaaatgcaa ctgaccaaac atttagtgaa gaaattaaaa gcggtttggt cttaacagac
     4381 ttctgggcta cttggtgcgg tccttgtaaa atgatagctc cagttcttga agaaattgac
     4441 gctgaaatgg gcgataaagt taaaatcgta aaattagatg ttgatgaaaa ccaagaaacg
     4501 gcagcaaaat acggtgtgat gagtattcca acattaattc tatttaaaga cggagaaatc
     4561 gtggataaag tcgttggata ccgtccaaaa gaagctttag aagaagttat taacaatcat
     4621 ttataatgtt gtaatcgtca attgacatgg cagtccattt tgggctgctt ttcttcattt
     4681 atataccttt tatctatctt tttatcccct aaaggaatta tagtataata ttagttatat
     4741 gaataacact caatatggag tgagcacatt ggaaacaaaa ccaaaaatta aagagaaatt
     4801 agcattattg ccagatcaac ctggttgtta tttaatgaag gaccggcaag ggacggttat
     4861 ctatgtcggg aaagcaaaag ttttaaaaaa tcgggtccgt tcttatttca caggatcgca
     4921 taatgcgaaa actcaagcat tggtaagtga aatagaggac tttgaatata ttataacgtc
     4981 atccgatgtc gaagcattaa ttttggagaa caatttaatt aaacaatatg atccaaaata
     5041 taatgtcatg ttgaaggatg ataaaacata tccgtttatt aagctgacgt ctgaacgtca
     5101 tccaaggtta atcattacgc gtaaagtaaa aaaaggtgac aaagccaaat attttggtcc
     5161 ctatgccaat gtttatgcag caagggaaac aaaaagatta ctcgacaagt tatatccgtt
     5221 acgtaaatgc caaacattac caaaacaagt gtgcttatat taccatattg gccaatgttt
     5281 agcaccttgt gtctttgatg tttcacagga aacatataaa aaaatgacga ccgagattac
     5341 aaagttttta aatggtggtt ataaagaagt aaagaaagat ctcactgaaa aaatgatcga
     5401 agccagtgaa aaattagatt ttgagcgggc gaaggagtat cgggataaaa tcacggccat
     5461 agaaatgacg atggaaaaac aaaaagcaac gatgaccgat catatagatc gagatgtttt
     5521 cggttatgct gcagacaaag gttggatgtg tgtccaagta ttctttgtcc gtcaaggaaa
     5581 attaattgaa cgggatgtgt cgatgtttcc ttattataaa gatcctgaag aagagatgct
     5641 aacattttta ggtcaatttt atgatcgacc agaacatttt aaaccgaaag aaatcttact
     5701 accgcaaaat gtggatgcag aactcgccca tgctttactt gatgtgaaaa ttgttcagcc
     5761 aaaacgggga caaaaaaagg aaatggttga acttgcaaac aaaaatgcga aagcagcatt
     5821 aaaagagaag ttttccttat tagagcggaa tgaagaacga acaataaaag cgatcgaaaa
     5881 attaggcgag caaatgaata tttatacgcc gtatcgtatt gaagccttcg acaactccaa
     5941 tattcaaggg acaaacccgg tatcggcaat ggtcgttttt acaaacggga tgccagataa
     6001 gaagcaatat cggaaatata aaattaaaac ggttgaagga ccagatgact atgactcgat
     6061 gcgagaggtt attcggagac ggtatacacg cgttttaaaa gaaaaccagc cactgcctga
     6121 tttaatctta attgatggtg gaaaaggaca aattgaagca gcgaaggatg ttttagaaaa
     6181 tgaacttggc cttgacattc cagttgcggg attagtaaaa gatgataagc atcaaacttc
     6241 taatttacta tttggtgatc caccagaaat ggtccctctt gctcgaaata gtcaagaatt
     6301 ctacttgctt cagcggattc aagatgaggt tcaccgtttt gcgatcacat tccatcgcca
     6361 attacgtgga aaatcgatga ttcaatccat tctcgatgaa ataccgggag tcggtcagaa
     6421 acgaaagcag ttattattaa agcatttcgg ttctgtaaaa aaaatgcagc atgcttctgt
     6481 tgaggatttc atgaaaattg ggataccgaa aaatgtggcc gaatccattg ttcaaacatt
     6541 acaaaactct gaagaatagg aagtcctttt aagtggattt ccttttttat tttttttgag
     6601 attttgtttc atggacaaaa aggtgaggaa aagaggttga aacgtctttg cgagaacttc
     6661 tcgcggacaa aagggaacca aaagagataa gaaaagtccg atcgagcatc tcacatttgc
     6721 gcacaataaa taatcagaaa atatgtattg attccattat ttcaacatgc tataatatag
     6781 ccaatttaat aaattcatgt tctgaaaaga cgtgaagata gaggcgcggt ttttaagagt
     6841 acatgtatgg agaagattgg acttctgtga aatacatgga aaggaaaaat cgccgaaaga
     6901 aaaaatagtc caattctatt ttttcttggt tctgctactg aataagtaca gaactgtcaa
     6961 gagttactct tggagagcta tctcactgtg aacacgctaa taattgcgtt tttgcaggca
     7021 atgggatttc tccattgtct tttgttttat cttgtacaag tttctagcgc tctccttaca
     7081 attttcacaa tgtgtaacaa tgtatttaaa atttggctta aacagctgaa aagaggggga
     7141 aaaaattggg cattattgta caaaaatttg gcggtacgtc ggtagcaacg gtagaaaaaa
     7201 tattaaatgt agcagatcga gttttagatg aaagaaaaag agggaataat gttgtcgtcg
     7261 ttgtatcagc aatgggaaaa tcaacggatg agttaatttc tttagctaaa caagtttcaa
     7321 ccaagcctag taaacgtgaa ttggatatgt tagtcacgac aggtgaacaa gtcacgattg
     7381 cattacttgc aatggcgctg catgaaaaag gacatgatgc agtgtcgatg acaggttggc
     7441 aagcgggggt ggaaacagaa ccgattcacg ggagtgcacg gattttgaac attgataccg
     7501 accggatcaa cagggcgatc cgtgaaggaa aaatcgtgat agttgctgga ttccaaggta
     7561 tcactgaaga tggagaaata acgacgttag gccgtggagg ttcagatacg tctgccgtcg
     7621 ctttagcagc agctctaggt gctgatcgat gcgatattta cacagatgta acgggtgtat
     7681 atactgccga tccacgttat attccgtctg cgagacaatt atcaactata tcttatgatg
     7741 aaatgttaga gttggcgaat ttaggtgcag gtgtgcttca tccaaggtct gttgaatttg
     7801 cgaaaaatta tcaaattcct ttagtcgttc gctcaagtac agaaaaagtg gaaggaactt
     7861 atgtattgga ggaaacaata atggaagaaa acttagttgt ccgcggtgtt gcctttgaaa
     7921 aagatattac aaaattaacg gtttatggtt tatcaaatga aattgcaagt ttatcatcgg
     7981 tatttactcc gttagctaaa aataacgtaa atgtggatat tattattcaa aatgcgtctg
     8041 accaaaactt gaatacacta tcattttcga ttaaaaccga tgagttgcaa gaggcattgc
     8101 aagtattgga agaacataaa gaatcaattg gttatgatca tattgaatat gaatcaggtt
     8161 tagcaaaagt atccattgtt ggttcaggca tgatttcaaa tccaggtgta gcggctcaaa
     8221 tgttcgcttc attagctgaa aaagatattt ttgtaaaaat ggtcagtact tcagaaatta
     8281 aagtatctgc tgtagtcaac gaagaccaaa tgttaaaggc tgctgaaata ctgcatgatg
     8341 ttttcggtct ttcaaaggta gaacaggaag taagtgttgc aaaataataa aaacgttaaa
     8401 aaacttcatc aagtgagtca gtcaactcat ttgatgaagt tttttgtaaa aaaatggtta
     8461 ttttacaatt gaaatgaata atataatgaa caatgtccac attatttata agtctataag
     8521 tggaatatca tcccatttca ctgtaaacaa tacttttcca tccttttttt tcggatgttc
     8581 aaaagtttcg gcataaactt tcttttgttg ggcaatttgt tcagcgagga agccggcctc
     8641 aagttggaat gttgcattgg ttcgtgttaa aatgcggtgt tttactaagt cgcttgttaa
     8701 ttgaagttcg atttcacttt tcttttggct aataatatcc aggttgcccc atcctgcatt
     8761 tcgaaaaaac tcttgaatct catcaaaaga aaataatgga tattttcgag cgatttgttt
     8821 tccgatccaa taaagaatac taggtgcatc ttcccctaaa atttcttcta taaaatcttc
     8881 acgaatcagt tcatatccaa atgcaggaac ggttaattca gttaagttta ttttttcttt
     8941 tactgttttt ctactcaaac tttgctcccc cttttcttca aatctattat atacaatttc
     9001 tgttcattta tttaacattt atttatttgg aaaaaaatta tattaaaata tcctcctaaa
     9061 atttagaatt tttattagga ctttatgaca actttatgaa actatcatgt gaagaaaaaa
     9121 atatttttca aatattatta aacctgtatc cgttttcttg acgggtttta taaaaaggtt
     9181 tacaattgag ttgttcatat atttgccata gtttttaaaa tttatagtca atgattaata
     9241 actaaggggg gtacatctta agatggcagg aaaccgtgag tttaataatc ggagattaca
     9301 ctcactatta ggagttcttc cgatcggtat tttcttaatt gtccatttaa caattaacta
     9361 tcaagcaaca aagggagcag aggcatataa tgcagctgca ggattgatgg aaaacatccc
     9421 atttctacta tttgtagaaa ctgtagtcat ttatattcct atattattcc acgcaatata
     9481 tggagtatac atagcgttta ctgcaaagcc aaacaatgtt cgtttcagta cttttagaaa
     9541 ctggatgttt gttttgcaaa gaattacagg ggttatcctc attatcttca ttgcgtggca
     9601 tgtgtgggag acacggattg cgaaggcact tggtgctgaa gtgaactttg acatgatggc
     9661 aaatatagtc gataatcctg caatgttagt gttctatatt gtcggaattg tttgtgcaac
     9721 attccactta tcgaacggtt tatggtcatt ctttgtaagt tgggggatta ccgtatcacc
     9781 tcgttcacaa agaattttga cgtatgttac aatgctagtt tttgtagctg taacatttat
     9841 aggtgttcgt gcaatcttag catttactgt ataaaactat atgactatgt gaagcgatta
     9901 cgagaaaacc ttacaactta tgtattgaac gtatgaatta atagattgat aggaacaacg
     9961 actagagatt acttaataat tgggggagtg agtcgcagaa atgagtaaag gtaaaattat
    10021 tgttgtcggt ggcggattgg caggcctaat ggcaacagtt aaaatagctg aggctggggt
    10081 gccagttgaa ttgttctctt tagttccggt aaaacgttct cactctgttt gtgcacaagg
    10141 tggaattaat ggagcggtta acacaaaagg tgaaggggac tcaccttgga aacactttga
    10201 tgatacggta tacggtggag acttcttagc aaaccaaccg cctgtaaaag caatgtgtga
    10261 agcggcacca ggtatcattc acttgtttga ccgtatgggg gttatgttta accgtactcc
    10321 agaaggttta ctagacttta gacgttttgg aggaacatta tatcatcgga ctgcctttgc
    10381 aggtgctaca acaggacaac aattgcttta tgcattagat gaacaagtac gtcgtcatga
    10441 agtagccggt ttagtaacga aatatgaagg ttgggaattc ttaggcgcca tcattgatga
    10501 tgatcaaaca tgccgtggta ttgtggcaca agatttaaaa tctggagaaa ttaaatcatt
    10561 ccctgcagat gcggttatta tggcaacagg tggtcttggt attatctttg gtaaatcaac
    10621 aaactctgtt ataaataccg gatcagctgc agcgattctt tatcaacaag gtgcgatcta
    10681 cgcgaacggt gaatttatcc agatccatcc tacagcaatc cctggagacg acaaattacg
    10741 tctcatgagt gaatctgctc gtggtgaggg tggtcgtgtc tggacctata aagatggtaa
    10801 accttggtac ttcttagaag aaaaatatcc attatacgga aacctagttc caagggatat
    10861 tgctacccgt gaaattttcg atgtatgtgt caaccaaaaa ttaggcatca acggggaaaa
    10921 tatggtttat ctagacctat cccataaaga tccacatgaa cttgatgtaa aacttggcgg
    10981 aattattgaa atttatgaga agttcacagg tgatgaccca cggaaagttc caatgaaaat
    11041 cttcccagct gtacactact caatgggtgg attatgggtt gactatgaac aacaaaccaa
    11101 tattaaaggt ttatttgccg ctggtgagtg tgactattca caacacggtg caaaccgtct
    11161 tggagcaaac tctttactat ctgctattta tggtggtatg gttgcaggtc caaacgcggt
    11221 taaatatatt gaaggtttag aaaagagcac agatgcctta ccttcaagct tgttcgaacg
    11281 ttatcaacgt caagaacaac aaaaatggga cgatatcttg aaaatggacg gaactgaaaa
    11341 cgcctatgta atccataaag aacttggtga atggatgaca gataacgtta ccgttgtacg
    11401 ttacaatgat aaactattaa agacagacga aaagattcaa gaattaatgg aacgctggaa
    11461 aaatattaat attaatgata cttcaagctg gagtaaccaa ggtgcacaat ttacaagaca
    11521 attgcaaaat atgctccatc ttgcgcgtgt tattacgctt ggtgcgtata accgtaatga
    11581 gtctcgtggt gcacattata aaccggaatt ccctgaacgt aatgatgaag aatggttaaa
    11641 aacaactatg gcttcgtatg atcctgctac aaatgcaccg aaatttgaat atgaagatgt
    11701 ggacgtatct ttaattaaac caagaaaacg tgattatacg acgacaagta aataagaagg
    11761 ggaggagaat attcaatggc tgaacaaaga aaaacagtga cttttataat ccaaagacaa
    11821 gacacaccgg attctacccc ttatgaggag acgtttgaaa ttccatatcg tccaaatatg
    11881 aatgtgatct cagcattgat ggaaattcaa cggaatccag taacaaaaga tggtaagaaa
    11941 acttcgccgg ttgcttggga aatgaactgt ttagaagaag tttgcggtgc ttgttcaatg
    12001 gttatcaacg ggaaacctag acaagcttgt tcgaccatgg ttgataaatt agagcatcct
    12061 attaaattag aaccgatgcg tacattccca gtagtacgtg acttagtaat tgacagaagt
    12121 cgtatgttcg actccttgaa gaaagtaaaa gcatggattc caattgatgg aacttatgat
    12181 ttaggacctg ggccaagaat gcctgaaaat aaacgtcaat gggcgtatga gctttcaaaa
    12241 tgtatgacgt gtggtgtatg tttagaagcc tgccctaacg tgaatgacaa atcaaacttt
    12301 atgggtcctg caccgttatc acaagttcgg ttatttaact cccatccaac aggtgcaatg
    12361 aataaagcag aacgtttaaa tgctattatg ggggatggcg gtttagctaa ctgtggtaac
    12421 tcacaaaact gtgtgcaagc ttgtccgaaa ggtattcctt taacaacgtc cattgcagca
    12481 ttaaaccgtg aagcgactgt tcaaatgttc cgtaacttct ttggtagtga ttattcctat
    12541 taattggtta cgtacaatca agaggctggg ccaactggat ggttcagcct ctcgttataa
    12601 agtaaaacga atgaatattc attcagtacg tgaaagggga ggttttcatg aaaaagatca
    12661 gctacataca agattttcca tcatggaaag cagggttcga attttttgta cccgttaaag
    12721 tcagattttc agaaaccgat atgtttggtc atttaaacaa tacggttccg ttcgtttatt
    12781 ttgaaacagc gagaattgaa tatatccatt atctcggact ttatcgacag gatttaaagg
    12841 aaatgaggga aacgattcca gtcgtcgcta atcaacaatg tgattatatt cggcaagtat
    12901 attttgatga agaactaaac atttacgtaa aaattaatga agttggtaat tcctcagttg
    12961 atcttcatta tctaggtgta aaaggcgatg atacggtctg ttttaccgga cgcggaacaa
    13021 ttgtaaacat caataaaaat agtggaaaat ctgttccttg gacaagtgaa gagagagaaa
    13081 ttttctttaa agcaatgaat gtcaatgtgg tttaaaataa taatgcctat ttcttacaga
    13141 atgggatgat tgctgtcact cccttcttgc cgttcacata tgatattgtg acgattcata
    13201 cccatccccg cgttttctag ctggcgaagg caaggagggt tcatgtattt gaaggagaat
    13261 gatttcactc ataa
//
