GCA_902850315.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

LR793256.1

Region	Type	From	To
Region 1	NRPS-like,NRPS	114,304	171,566
Region 2	RiPP-like	305,504	315,984
Region 3	lassopeptide	581,101	603,536
Region 4	T3PKS	635,594	676,760
Region 5	RiPP-like	1,943,308	1,953,541

LR793256.1 - Region 1 - NRPS,NRPS-like

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Location: 114,304 - 171,566 nt. (total: 57,263 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 114303 - 171566:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal - gly) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 114303 - 155825:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal - gly) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 117597 - 171566:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal - gly) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_118

CAL_domain (47..468): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 160.9
NH2: 22.7
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

ctg1_119

PKS_AT (7..289): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 57.3
inactive: 57.0
Methoxymalonyl-CoA: 36.7
Methylmalonyl-CoA: 21.1
Ethylmalonyl-CoA: 16.7
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg1_120

Search NORINE for peptide: strict or relaxed

AMP-binding (1606..1997): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DIvQLGVvWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 80% (moderate)

ctg1_121

Search NORINE for peptide: strict or relaxed

AMP-binding (1009..1394): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DASTLaAICK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 90% (moderate)

LR793256.1 - Region 2 - RiPP-like

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Location: 305,504 - 315,984 nt. (total: 10,481 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

LR793256.1 - Region 3 - lassopeptide

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Location: 581,101 - 603,536 nt. (total: 22,436 nt) Show pHMM detection rules used

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Lasso peptides

Similar known gene clusters

No matches found.

Lasso peptide predictions

Lassopeptides - No core peptides found.

Lasso peptides

Core peptide predictions

No core peptides found.

LR793256.1 - Region 4 - T3PKS

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Location: 635,594 - 676,760 nt. (total: 41,167 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

No matches found.

LR793256.1 - Region 5 - RiPP-like

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Location: 1,943,308 - 1,953,541 nt. (total: 10,234 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

No matches found.