MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AEZ64539.1 glycine_betaine/L-proline_ABC_transporter,_ATPase_subunit BGC0001065 Polyketide 39.0 93.2 248.0 1.3e-65
CAD91242.1 hypothetical_protein BGC0000289 NRP:Glycopeptide + Saccharide:Hybrid/tailoring 40.0 92.7 238.0 2.3e-62
QCE20595.1 ABC_transporter BGC0001961 NRP 38.0 91.6 233.0 7.3e-61
CAK15811.1 putative_polyamine_ABC_transporter,_ATP_binding_protein BGC0000344 NRP 40.0 61.3 183.0 6.7e-46
AAU39356.1 putative_spermidine/putrescine_ABC_transporter_ATP-binding_protein BGC0000381 NRP 37.0 61.8 174.0 4e-43
ABC37732.1 putrescine_ABC_transporter,_ATP-binding_protein BGC0001120 NRP + Polyketide:Modular type I 37.0 62.0 169.0 1.3e-41
AMD57704.1 proline/glycine_betaine_ABC_transporter_ATP-binding_protein BGC0001765 Saccharide 38.0 57.7 168.0 1.7e-41
AQP25584.1 glutamate_ABC_transporter BGC0001590 Polyketide 37.0 60.8 151.0 3.7e-36
BAK64654.1 putative_transporter BGC0000135 Polyketide 36.0 58.0 143.0 7.6e-34
AHI59113.1 ATPase BGC0001005 NRP + Polyketide 38.0 56.7 142.0 1.7e-33
RLV71182.1 Peptide_ABC_transporter,ATP-binding_protein BGC0001846 NRP + Saccharide:Hybrid/tailoring 35.0 61.5 141.0 2.2e-33
CAE02640.1 YckI_protein BGC0000433 NRP:Lipopeptide 35.0 59.0 140.0 5e-33
CUX79067.1 Bicarbonate_transport_ATP-binding_protein_CmpC BGC0001715 NRP 37.0 53.7 139.0 8.5e-33
AHN91916.1 ABC_transporter BGC0000340 NRP 32.0 64.3 136.0 7.2e-32
AWM72908.1 ABC-transporter_(ATP-binding) BGC0001719 Polyketide 35.0 63.8 134.0 2.7e-31
WP_013310325.1 ABC_transporter_ATP-binding_protein BGC0001728 NRP + Polyketide 36.0 58.2 131.0 3.9e-30
AHY86401.1 ABC_transporter_protein BGC0000329 NRP 34.0 55.9 129.0 1.1e-29
ACR33057.1 ABC_transporter BGC0000495 RiPP:Lanthipeptide 36.0 57.0 128.0 3.3e-29
KUM69048.1 ABC_transporter_ATP-binding_protein BGC0001561 NRP 35.0 52.4 127.0 4.3e-29
AHL46714.1 ABc_transporter_protein BGC0001179 Polyketide:Type II 33.0 61.0 127.0 5.7e-29
ATU31790.1 ABC_transporter_ATP-binding_protein BGC0001814 NRP 35.0 51.6 126.0 9.7e-29
BAG84245.1 putative_ABC-transporter BGC0000257 Polyketide 34.0 55.7 126.0 1.3e-28
AAY37657.1 ABC_transporter:Protein_of_unknown_function_DUF214 BGC0000437 NRP 36.0 51.6 125.0 1.6e-28
ADO17962.1 CclG BGC0000487 RiPP:Head-to-tailcyclized peptide 36.0 57.0 125.0 1.6e-28
ALD83698.1 ABC_transporter_ATP_binding_protein BGC0001299 Polyketide 34.0 57.2 125.0 2.2e-28
ANH11417.1 SceV BGC0001908 Polyketide 33.0 55.9 124.0 2.8e-28
ANZ15844.1 putative_ABC_transporter_ATP-binding_protein BGC0001569 NRP 32.0 56.2 124.0 3.7e-28
AAG32539.1 SalX BGC0000548 RiPP:Lanthipeptide 34.0 54.4 123.0 8.2e-28
ACN80635.1 Sio4 BGC0000655 Terpene 36.0 58.5 123.0 1.1e-27
AHZ34249.1 MacB BGC0001389 NRP 33.0 55.9 122.0 1.4e-27
AXM42912.1 ABC_transporter_ATP-binding_protein BGC0001940 Polyketide 33.0 54.2 122.0 1.4e-27
CAD91214.1 putative_ABC_transporter,_Dbv19 BGC0000289 NRP:Glycopeptide + Saccharide:Hybrid/tailoring 35.0 55.7 122.0 1.8e-27
BAW27681.1 transporter BGC0001764 NRP 36.0 49.9 122.0 1.8e-27
AHZ34236.1 MacB BGC0000323 NRP:Lipopeptide 34.0 56.7 121.0 2.4e-27
YP_002539412.1 EtsB BGC0001555 RiPP 30.0 73.4 121.0 2.4e-27
CAK15812.1 macrolide_ABC_efflux_protein_MacB BGC0000344 NRP 35.0 51.6 121.0 3.1e-27
AFJ23828.1 MacB-like_ABC_transporter_protein BGC0001838 NRP 33.0 62.5 121.0 3.1e-27
CCJ67642.1 macrolide_export_ATP-binding/permease_protein_MacB BGC0000447 NRP:Lipopeptide 33.0 66.8 121.0 4.1e-27
WP_064118557.1 MacB_family_efflux_pump_subunit BGC0001509 NRP 37.0 51.6 121.0 4.1e-27
ADU86007.1 putative_ABC_transporter-related_protein BGC0000165 Polyketide:Modular type I 34.0 50.9 120.0 5.3e-27
AAY93343.1 efflux_ABC_transporter,_ATP-binding/permease_protein BGC0000413 NRP 34.0 56.2 120.0 5.3e-27
AJW76714.1 DsaL BGC0001196 NRP 35.0 51.9 120.0 5.3e-27
AFH75324.1 macrolide_export_ATP-binding/permease_protein_MacB BGC0000425 NRP:Cyclic depsipeptide 34.0 55.9 120.0 6.9e-27
QDF82252.1 macrolide_export_ATP-binding/permease_protein BGC0001980 NRP 36.0 51.6 119.0 9.1e-27
AWR88445.1 hypothetical_protein BGC0001522 Polyketide 34.0 48.9 119.0 1.5e-26
AVI57415.1 AbmF4 BGC0001694 Polyketide 29.0 62.0 119.0 1.5e-26
orf4 ABC_transporter_ATP-binding_protein BGC0001429 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 32.0 57.0 116.0 7.7e-26
APZ78843.1 ABC_transporter_ATP-binding_protein BGC0001431 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 32.0 57.0 118.0 2e-26
AOA33125.1 ABC_transporter_ATP-binding_protein BGC0001346 NRP:Cyclic depsipeptide 37.0 51.6 118.0 2.6e-26
ABA73958.1 macrolide-specific_ABC-type_efflux_carrier BGC0001842 NRP:Lipopeptide 36.0 51.6 118.0 3.4e-26
AGM14936.1 MacB-like_ABC_transporter_protein BGC0000463 NRP:Lipopeptide 33.0 55.9 117.0 4.5e-26
ALA09377.1 ABC_transporter BGC0001303 Polyketide 34.0 55.9 117.0 4.5e-26
CCG06125.1 putative_oligopeptide_ABC_transporter,_ATPase BGC0001543 Polyketide 29.0 63.5 117.0 5.9e-26
AAO56331.1 syringafactin_efflux_protein_SyfD BGC0000435 NRP 36.0 51.6 116.0 7.7e-26
APZ78819.1 ABC_transporter_ATP-binding_protein BGC0001429 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 32.0 57.0 116.0 7.7e-26
AAM97297.1 lipoprotein_releasing_system_ATP-binding_protein_LolD BGC0001688 Other 34.0 52.7 116.0 7.7e-26
AFH75332.1 macrolide_export_ATP-binding/permease_protein_MacB BGC0000398 NRP:Cyclic depsipeptide 36.0 53.9 116.0 1.3e-25
ABW17379.1 MacB BGC0000411 NRP 34.0 55.9 116.0 1.3e-25
ARE67845.1 AbsF4 BGC0001492 Polyketide 30.0 57.2 116.0 1.3e-25
CAA60452.1 ABC-transporter BGC0001040 NRP + Polyketide 30.0 55.9 115.0 1.7e-25
ABP55202.1 ABC_transporter_related BGC0000142 Polyketide 33.0 54.9 114.0 2.9e-25
BAX64249.1 ABC_transporter BGC0001623 NRP + Polyketide 29.0 60.3 114.0 2.9e-25
AAY91423.1 efflux_ABC_transporter,_permease/ATP-binding_protein BGC0000399 NRP:Cyclic depsipeptide 35.0 51.6 114.0 3.8e-25
AEH59056.1 YvcC/ABC_transporter BGC0000385 NRP 36.0 55.7 113.0 8.5e-25
BAC98762.1 NukF BGC0000539 RiPP:Lanthipeptide 27.0 74.7 113.0 8.5e-25
CAY48791.1 macrolide-specific_ABC-type_efflux_carrier BGC0001312 NRP 31.0 63.5 113.0 8.5e-25
DAB41657.1 ABC_transporter BGC0001585 Alkaloid 33.0 57.0 113.0 1.1e-24
BAM09402.1 putative_ABC-transporter BGC0000619 RiPP 31.0 60.8 112.0 1.9e-24
BBE52944.1 putative_ABC-transporter BGC0001602 RiPP 31.0 60.8 112.0 1.9e-24
ALX37944.1 GaeT BGC0001388 RiPP 30.0 60.8 111.0 2.5e-24
BAV56269.1 hypothetical_protein BGC0001657 NRP 36.0 55.7 111.0 2.5e-24
ABS50188.1 putative_ABC_transporter_permease/ATP-binding_protein BGC0000410 NRP 29.0 55.2 111.0 4.2e-24
ABQ84449.1 salivaricin_ABC-transporter BGC0000624 RiPP 33.0 55.7 110.0 5.5e-24
WP_030684648.1 ABC_transporter_ATP-binding_protein BGC0001607 Other 35.0 49.6 108.0 2.1e-23
AQZ42156.1 putative_ABC_multidrug_transporter BGC0001820 NRP 31.0 61.3 108.0 2.1e-23
CBJ61632.1 PtnG_protein BGC0000569 RiPP:LAP 30.0 59.2 108.0 3.6e-23
XP_011392729.1 ABC_transporter BGC0001281 Polyketide 30.0 54.9 107.0 6.1e-23
AAG05696.1 probable_ATP-binding_component_of_ABC_transporter BGC0000287 NRP 33.0 53.7 106.0 7.9e-23
ABW74893.1 ABC_transporter BGC0000759 Saccharide 30.0 58.2 106.0 7.9e-23
AAC44070.1 unknown BGC0000797 Saccharide 29.0 58.2 106.0 7.9e-23
EEM14530.1 hypothetical_protein BGC0001210 RiPP 30.0 58.0 106.0 7.9e-23
AEP18658.1 efflux_transporter BGC0000461 NRP 35.0 55.4 106.0 1e-22
AAP57696.1 putative_secretion_protein BGC0000768 Saccharide 29.0 58.2 106.0 1e-22
ACG70837.1 ATP-binding_phosphonate_ABC_transporter_PhnC BGC0000938 Other:Aminocoumarin 30.0 59.0 106.0 1e-22
EYT83450.1 ABC_transporter BGC0001213 Polyketide 28.0 58.7 106.0 1.4e-22
CBW74823.1 Multidrug_resistance_ABC_transporter_ATP-binding_and_permease_protein BGC0000571 RiPP:Lassopeptide 30.0 64.1 104.0 3e-22
BAH43868.1 probable_ABC_transporter_ATP_binding_protein BGC0000367 NRP 30.0 56.5 103.0 6.7e-22
AHJ59536.1 ABC_transporter_protein BGC0000502 RiPP:Lanthipeptide 30.0 58.0 103.0 6.7e-22
AFD30962.1 CrmT3 BGC0000966 NRP + Polyketide 28.0 57.2 102.0 1.5e-21
WP_003211121.1 ABC_transporter_ATP-binding_protein BGC0001173 RiPP:LAP 29.0 70.9 102.0 1.5e-21
ANP43732.1 ThsT BGC0001391 RiPP 33.0 53.4 102.0 2e-21
AOT85870.1 ABC_transporter BGC0001789 RiPP 31.0 57.2 102.0 2e-21
EMC15128.1 ABC_transporter,_ATP-binding_and_permease_protein BGC0000530 RiPP:Lanthipeptide 31.0 55.9 101.0 2.6e-21
AHF21231.1 PabF BGC0000542 RiPP:Lanthipeptide 26.0 59.2 100.0 5.7e-21
ADI10107.1 type_II_lanthionine_synthetase_and_transporter BGC0001229 RiPP:Lanthipeptide 27.0 61.3 100.0 5.7e-21
ABA00880.1 NsuT BGC0000537 RiPP:Lanthipeptide 29.0 59.5 100.0 7.4e-21
CAA12529.1 ExsA_protein BGC0000802 Saccharide 29.0 55.7 100.0 7.4e-21
AHF21240.1 CrnT BGC0000500 RiPP:Lanthipeptide 28.0 58.7 99.0 9.7e-21
BAB78441.1 BGC0000555 RiPP:Lanthipeptide 30.0 58.2 99.0 9.7e-21
ABI30231.1 McdF BGC0000526 RiPP:Lanthipeptide 31.0 55.7 99.0 1.3e-20
AAS92552.1 SirA BGC0001044 NRP + Polyketide 29.0 65.3 99.0 1.3e-20
AFW17839.1 PaeF BGC0000541 RiPP:Lanthipeptide 27.0 55.7 99.0 1.7e-20
EFI65097.1 lantibiotic_transport_protein BGC0001407 RiPP 31.0 59.2 99.0 1.7e-20
ATY37607.1 BreB BGC0001536 NRP 31.0 55.2 99.0 1.7e-20
CAJ88628.1 putative_netropsin_resistance_protein_subunit_1 BGC0000327 NRP 28.0 58.2 98.0 2.2e-20
BAE56595.1 BGC0001123 NRP 25.0 65.3 98.0 2.2e-20
AVH76806.1 BcrA BGC0001669 RiPP 27.0 63.8 98.0 2.2e-20
ALE27499.1 ABC_transporter BGC0001292 Other 29.0 59.2 97.0 3.7e-20
AEZ64558.1 ABC-type_Fe3+-siderophore_transporter_ATP-binding_protein BGC0001065 Polyketide 27.0 55.2 97.0 4.8e-20
ADP94229.1 TunI BGC0000880 Other:Nucleoside 25.0 55.4 97.0 6.3e-20
AAG32538.1 SalT BGC0000548 RiPP:Lanthipeptide 33.0 60.8 96.0 8.2e-20
ALV82355.1 ABC_transporter BGC0001370 NRP 27.0 55.2 96.0 1.4e-19
BAH43767.1 ABC_transporter_ATP_binding/permease_protein BGC0000452 NRP 27.0 58.2 95.0 1.8e-19
EEM79978.1 ABC_transporter BGC0001887 RiPP 27.0 54.2 95.0 1.8e-19
CAP20370.1 ABC_transporter,_ATP-binding_membrane_protein BGC0000347 NRP 29.0 57.7 94.0 3.1e-19
AKQ99290.1 ABC_transporter,partial BGC0001484 Other 28.0 58.7 94.0 3.1e-19
CAN02020.1 putative_ABC_transporter,_ATP-binding_protein BGC0000528 RiPP:Lanthipeptide 27.0 62.0 94.0 4.1e-19
BAG71481.1 ATP-binding_cassette_transporter BGC0000536 RiPP:Lanthipeptide 28.0 60.8 94.0 5.3e-19
AAX31540.1 putative_ABC_transporter_ATP-binding_protein BGC0000336 NRP 26.0 60.5 93.0 6.9e-19
CAB38879.1 putative_ABC_transporter BGC0000315 NRP:Ca+-dependent lipopeptide 27.0 55.2 93.0 9.1e-19
BAB04170.1 lantibiotic_haloduracin_protease_and_transporter BGC0000517 RiPP:Lanthipeptide 29.0 58.0 93.0 9.1e-19
ATQ39429.1 ABC_transporter BGC0001565 NRP 29.0 60.5 93.0 9.1e-19
ATG31926.1 KocI BGC0001640 RiPP 28.0 55.4 93.0 9.1e-19
ACX68646.1 transport_ATP-binding_protein BGC0000547 RiPP:Lanthipeptide 29.0 55.2 92.0 1.2e-18
AFL48543.1 putative_peptide_transporter_(ATP-binding_subunit) BGC0000084 Polyketide 33.0 32.2 92.0 2e-18
CAD89782.1 hypothetical_protein BGC0001010 NRP + Polyketide:Modular type I 26.0 55.7 91.0 2.6e-18
YP_002539287.1 IroC,_ABC_transport_protein BGC0001555 RiPP 29.0 57.7 91.0 2.6e-18
WP_082829620.1 pallidocin_leader_peptidase/ABC_transporter BGC0001930 RiPP 30.0 50.6 91.0 2.6e-18
ADX66464.1 ScnA BGC0000108 Polyketide 29.0 55.7 91.0 4.5e-18
CUX79064.1 putative_ABC_transporter_ATP-binding_protein BGC0001715 NRP 29.0 57.7 91.0 4.5e-18
AAM54082.1 ABC_transporter BGC0000020 Polyketide 28.0 55.7 90.0 5.9e-18
CAC20924.1 PimA_protein BGC0000125 Polyketide 30.0 56.2 90.0 5.9e-18
AQT01390.1 SgnA BGC0001690 Polyketide 30.0 56.2 90.0 5.9e-18
ADJ56354.1 NisT BGC0000535 RiPP:Lanthipeptide 30.0 57.2 89.0 1e-17
ABS50189.1 putative_ABC_transporter_permease/ATP-binding_protein BGC0000410 NRP 28.0 55.2 89.0 1.3e-17
AQZ37089.1 ABC_transporter_transmembrane_region_protein BGC0001511 Polyketide 28.0 56.7 89.0 1.3e-17
AEG64672.1 ABC_transporter-like_protein BGC0000379 NRP 29.0 58.5 89.0 1.7e-17
AAA62651.1 BGC0000504 RiPP:Lanthipeptide 29.0 56.2 89.0 1.7e-17
AGM16416.1 paenibacterin_ABC-transporter_E BGC0000400 NRP 27.0 62.8 88.0 2.2e-17
CAA79469.1 NisT_protein BGC0000538 RiPP:Lanthipeptide 30.0 57.0 88.0 2.2e-17
AAG28766.1 CoaD BGC0000617 RiPP 30.0 62.0 88.0 2.2e-17
AVX51096.1 nysH BGC0001709 Polyketide 29.0 53.2 88.0 2.2e-17
AFJ14797.1 PlpH BGC0000403 NRP 29.0 55.4 88.0 2.9e-17
CAB60262.1 MrsT_protein BGC0000527 RiPP:Lanthipeptide 25.0 63.5 88.0 2.9e-17
BAP05577.1 calU BGC0000967 NRP + Polyketide:Trans-AT type I 27.0 57.7 88.0 2.9e-17
MAA_10048 multidrug_resistance_protein BGC0000337 NRP 28.0 62.5 87.0 3.8e-17
AHX39584.1 ABC_transporter_protein BGC0000626 RiPP 28.0 50.4 87.0 3.8e-17
WP_039794832.1 ABC_transporter_ATP-binding_protein BGC0002011 Polyketide 29.0 49.4 87.0 3.8e-17
EDY04298.1 ABC_transporter-related_protein BGC0000516 RiPP:Lanthipeptide 29.0 59.5 87.0 6.5e-17
WP_009985599.1 ATP-binding_cassette_domain-containing_protein BGC0001311 RiPP:Lanthipeptide 25.0 55.7 86.0 8.5e-17
EHK80158.1 ABC_transporter BGC0001447 Polyketide 25.0 51.4 86.0 8.5e-17
CAG38692.1 transport_protein BGC0000708 Saccharide 27.0 56.5 85.0 1.9e-16
ACA97579.1 PmxD BGC0000408 NRP 28.0 55.4 85.0 2.5e-16
AEZ51519.1 pmxD BGC0001153 NRP:Lipopeptide 28.0 55.4 85.0 2.5e-16
EOO99818.1 hypothetical_protein BGC0001861 RiPP:Glycocin 28.0 51.6 85.0 2.5e-16
AJM89737.1 PmxD BGC0001192 NRP 28.0 55.4 84.0 5.5e-16
ACP43452.1 McnB BGC0000590 RiPP:Microviridin 29.0 54.2 83.0 7.2e-16
AAF71764.1 nysH BGC0000115 Polyketide:Modular type I + Saccharide:Hybrid/tailoring 27.0 55.7 82.0 1.2e-15
BAH43768.1 ABC_transporter_ATP-binding/permease_protein BGC0000452 NRP 28.0 55.9 82.0 1.2e-15
OJF16286.1 AceT1 BGC0001491 Polyketide 26.0 60.0 82.0 1.6e-15
ctg1_orf1268 BGC0001752 NRP 27.0 52.7 81.0 2.7e-15
ACU62760.1 ABC_transporter_related BGC0001392 RiPP 28.0 53.7 81.0 3.6e-15
AFO93372.1 ABC_transporter,_ATP-binding_protein BGC0001362 Other 26.0 61.0 81.0 4.7e-15
WP_051767685.1 ABC_transporter_ATP-binding_protein BGC0002009 Polyketide 26.0 58.7 80.0 7.9e-15
WP_012444311.1 peptidase_domain-containing_ABC_transporter BGC0002005 RiPP 27.0 50.9 79.0 1e-14
CAG34716.1 putative_ABC_transporter BGC0000713 Saccharide 26.0 56.7 78.0 2.3e-14
ctg1_orf5 BGC0000321 NRP 31.0 44.3 78.0 3e-14
WP_009985592.1 peptidase_domain-containing_ABC_transporter BGC0001311 RiPP:Lanthipeptide 26.0 58.2 78.0 3e-14
ABL74935.1 ABC_multi-drug_transport BGC0001048 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 29.0 52.7 77.0 3.9e-14
CAB65192.1 Wzt_protein BGC0000775 Saccharide 26.0 55.9 76.0 8.8e-14
WP_106429829.1 peptidase_domain-containing_ABC_transporter BGC0000554 RiPP:Lanthipeptide 29.0 41.3 76.0 1.5e-13
EEM79980.1 ABC_transporter BGC0001887 RiPP 31.0 49.4 76.0 1.5e-13
AHI77484.1 ABC_transporter_family_protein BGC0000572 RiPP:Lassopeptide 27.0 52.2 74.0 5.7e-13
CAA07371.1 StrW BGC0000690 Saccharide 26.0 53.4 74.0 5.7e-13
CAJ96467.1 ABC-type_transporter,_ATPase_and_permease_components:_Pep3E_family BGC0000330 NRP:NRP siderophore 26.0 53.2 72.0 2.2e-12
BAG22745.1 putative_ABC-type_multidrug_transport_system_ATPase_and_permease_component BGC0000724 Saccharide 24.0 57.0 71.0 2.8e-12
AAL08400.1 MceG BGC0000586 RiPP:Microcin 31.0 47.3 71.0 3.7e-12
CAF33314.1 putative_ABC_transporter,_ATP-binding_protein,_NeoT BGC0000709 Saccharide 23.0 70.1 71.0 4.8e-12
CAH58692.1 putative_exporter BGC0000711 Saccharide 23.0 70.1 71.0 4.8e-12
BAE46917.1 goadsporin_biosynthetic_protein BGC0000565 RiPP:LAP 28.0 56.2 69.0 1.4e-11
ADD45300.1 ABC_transporter_related_protein BGC0000807 Saccharide 23.0 49.9 63.0 7.7e-10
CAC60277.1 RumT_protein BGC0000545 RiPP:Lanthipeptide 25.0 57.7 61.0 3.8e-09
AJV88390.1 MfnR BGC0001214 NRP 25.0 56.7 61.0 5e-09
AAD28497.1 McjD BGC0000581 RiPP:Linaridin 25.0 56.5 59.0 1.1e-08
ATY72532.1 ABC_transporter_ATP-binding_protein BGC0001574 NRP 24.0 52.7 56.0 1.2e-07
ANY94424.1 UvrA-like_drug_resistance_pump BGC0001584 Polyketide 29.0 41.0 51.0 3e-06
CCT75968.1 related_to_multidrug_resistance_protein BGC0001606 Polyketide 24.0 56.5 51.0 4e-06