GCA_905071825.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

CAJHJQ010000001 (original name was: CAJHJQ010000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	T3PKS	195,225	236,391

CAJHJQ010000004 (original name was: CAJHJQ010000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	RiPP-like	76,089	88,185

CAJHJQ010000008 (original name was: CAJHJQ010000008.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	NRPS	25,182	79,942	salivaricin 9	RiPP:Lanthipeptide	45%

CAJHJQ010000010 (original name was: CAJHJQ010000010.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	RiPP-like	30,300	54,615

CAJHJQ010000018 (original name was: CAJHJQ010000018.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 18.1	lassopeptide	1	21,772

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	T3PKS	195,225	236,391
Region 4.1	RiPP-like	76,089	88,185
Region 8.1	NRPS	25,182	79,942	salivaricin 9	RiPP:Lanthipeptide	45%
Region 10.1	RiPP-like	30,300	54,615
Region 18.1	lassopeptide	1	21,772

Compact view

c00001_CAJHJQ0.. - Region 1 - T3PKS

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Location: 195,225 - 236,391 nt. (total: 41,167 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00004_CAJHJQ0.. - Region 1 - RiPP-like

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Location: 76,089 - 88,185 nt. (total: 12,097 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00008_CAJHJQ0.. - Region 1 - NRPS

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Location: 25,182 - 79,942 nt. (total: 54,761 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 25181 - 79942:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - D-val) + (X - ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg8_52

Search NORINE for peptide: strict or relaxed

AMP-binding (182..619): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gLfwIaEcmK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 40% (weak)

AMP-binding (1793..2180): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGaTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

ctg8_53

Search NORINE for peptide: strict or relaxed

AMP-binding (35..465): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: agmWLGASGK
Nearest Stachelhaus code:: alpha-hydroxy-isocaproic-acid
Stachelhaus code match:: 70% (weak)

AMP-binding (1853..2242): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

c00010_CAJHJQ0.. - Region 1 - RiPP-like

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Location: 30,300 - 54,615 nt. (total: 24,316 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00018_CAJHJQ0.. - Region 1 - lassopeptide

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Location: 1 - 21,772 nt. (total: 21,772 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Lasso peptides

Similar known gene clusters

No matches found.

Lasso peptide predictions

Lassopeptide(s) for allorf_06954_07076 - Putative Class II

allorf_06954_07076 leader / core peptide / cleaved tail: MNYTKPVIEKISTFKSGTS - GLVAGRFRDIFGGRALFLIRI

Lassopeptide(s) for ctg18_7 - Putative Class II

ctg18_7 leader / core peptide / cleaved tail: MKYCKPTFEPIATFKKDTK - GLWTGNFRDVFGGRAIVRVKIEF

Legend:

Red: Putative macrolactam
Purple: Putative cleaved off residues

Lasso peptides

Core peptide predictions

ctg18_7 - Class II: Cleavage pHMM score: -8.80; RODEO score: 16; Monoisotopic mass: 2618.4 Da; Molecular weight: 2620.0 Da; Number of bridges: 0
allorf_06954_07076 - Class II: Cleavage pHMM score: -8.10; RODEO score: 18; Monoisotopic mass: 2328.4 Da; Molecular weight: 2329.8 Da; Number of bridges: 0