LOCUS       c00012_CAJHQN0..       23185 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CAJHQN010000012.1 Lacticaseibacillus paracasei isolate IBR071 genome
            assembly, contig: LPIBR_Contig_2, whole genome shotgun sequence.
ACCESSION   CAJHQN010000012
VERSION     CAJHQN010000012
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 23:18:23
            Original ID  :: CAJHQN010000012.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 271240
            Orig. end    :: 294425
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23185
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[276240:289425]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..18185
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..23185
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23185
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(173..457)
                     /locus_tag="ctg12_251"
                     /transl_table=11
                     /translation="LGGKETRLFQAIDGAYNDAAVQQDDEIKRFLFESAQRLASGDRFS
                     YVAARLDSFIASYSQFHHFQYPSALEPVYKLVAGASMRARGGGGLSVWL"
     CDS             complement(689..940)
                     /locus_tag="ctg12_252"
                     /transl_table=11
                     /translation="MSILKWYAGGQDRAEQAISILTELVADLNHSQQKMPLQQVLSDYI
                     EAFRKKDSAVPFILSRMNLDISSALKKQPDCVNCFRVG"
     CDS             complement(1042..2397)
                     /locus_tag="ctg12_253"
                     /transl_table=11
                     /translation="MTAKSNQTARGTRPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLSQSGVNTDKLDALERFVRNFEKQYTTETVREIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPVEMVCCFVGAGIGNWLRGIMIRRSWTLLACIGVSVAVACLAYFLVF
                     RGLEMSLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMIVHLRPENFVDLGLNPMLLLLFRLIASFSGVFGFSVMFNSPKRMAVQAGL
                     IGAVANTLRLELVDLSTIPPAAAAFIGALVAGLLASAINRIDGYPRISLTVPSIVIMVP
                     GLYIYRAIYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRKSD"
     CDS             complement(2703..2963)
                     /locus_tag="ctg12_254"
                     /transl_table=11
                     /translation="MGGVICYAVPVFWKRILRRHLIHEIKTLNQGLQLSSKAMSQLIDP
                     ENPYMVFADENGELDFSFLWLGNLRQLRRELRLIKEQKARV"
     CDS             complement(3087..3437)
                     /locus_tag="ctg12_255"
                     /transl_table=11
                     /translation="MEYQLEMEARKLIMILRHEIHQLHPLNRSPEMAYVVDRVAGDMDN
                     ELPHGPEFDRQLFRFAQKIDFILSTQSIQLSQLGRDAIDDIRRLANGEPLGKPEPERHG
                     LQRFFAHLFGCN"
     CDS             complement(3611..4990)
                     /locus_tag="ctg12_256"
                     /transl_table=11
                     /translation="MIDLKKLETTEFYNHRYRNFSTVIIVPTAILFVLLLLFLIFAKRE
                     VTVLTAAEIAPVKTAVTVQGTAANRIVTNHMKEGKHVKRGDTLLVYHDVAHPAQLKVLE
                     QQLATLKDQKAQLEVLNQSIAANKNLFASPDKFGYQQQVRDYLSQRRVYELESEALHAT
                     QGVADGKSKEIDQLLQTSMQASEAKMTAIREAQMAIRTDRPLSDNHAYNYLYLQYKAEA
                     KNADAANLNSLKGQYQSQLQSLLTTEKETLASLRTQRINQKQADLSAQQTGQNEAKLAS
                     LQSHMQQTMTAEQVKVQQGTQEGEAKLAALKDESKNYQVKASASGVLHLEASLSGNKYI
                     PAGTVLAQILPDLATQKEAELKLAVSPAEIMSLKRGQSVRLRIAENVPSPMTLTGRIDA
                     IDVAPTVNAKVGNYFKVQARVPLSERQRQTLHYGIAGQAAVITGTKTYWQYFVDKMFNH
                     Q"
     CDS             complement(5001..7193)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 307.5; E-value:
                     3.1e-93)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_257"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1107.8,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.4e-40, bitscore:
                     130.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSL
                     AHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKADMTLFDLDDVPYPFLVHVLKRGEL
                     LHYYVVFKATKDHILIGDPDSSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKEDKGS
                     LFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGL
                     ILAYVLQSVLTYGQNFLMAVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSD
                     ANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLVSLIAVPCYLVIVFAFQRPFN
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQ
                     LQQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKL
                     QMAKVANNRLNEVYLVESEFKEQRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEI
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPISDVDLTTLRQYIEYVP
                     QDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILS
                     GGQKQRLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIA
                     AKTEQIVVMDHGAIVEQGNHAELLAKQGYYARLVSE"
     CDS             complement(7660..7797)
                     /locus_tag="ctg12_258"
                     /transl_table=11
                     /translation="MKQFDEQKMVNMSDEELLGFIGGDSIRDVSPTFNKIRRWFDGLFK
                     "
     CDS             7987..9285
                     /locus_tag="ctg12_259"
                     /transl_table=11
                     /translation="METYSDLAYILLTSPVFILGITFLSYIFFNRINLIHIFFWSILAM
                     VLSTTLSLLGEILFGLIYAYYMSKTHNRSDVFWVFLFLEINLIIVNFQTLLEKSFTLSM
                     TNNFFFISITSKLITNIILLILAIWLFGTRKKIVNNMRHLVQEKDGIWMSAIFYLGASW
                     TVMYFLEFTFILLKLDNVLALLILSAFIFFMVVNLCSLFFILRSYRYYLELLVVKHTNE
                     SRRAYYASLNQQRENTSKLLHDYKNLLATLQLSLQQTSASQSSDTSNIIAQAQRSIQQA
                     ESGKDSLAAIESDPLRNLLYLKWSEATNSGIRLHIHTEGTIQPLSNNAGFAVIRALGIL
                     IDNALEESIRINKTHFSVLLVASDRGLEASVVNDINDDFNLAKFAEPGFTTKGRGHGNG
                     LTIINELIQQNKNIIIKKTVINKQLKITLFIGR"
     CDS             9290..10096
                     /locus_tag="ctg12_260"
                     /transl_table=11
                     /translation="MTNHQTMLKIFILEDNADFLNFLESTLRNYIMIEALHAEIKFTTQ
                     SATDLLDAVDLEEINDCLFLLDIDIPGSSVSGIDIATILRKKSLYADIMFITSHTEEAL
                     SILAHKIALLDLIDKSVLFEVEARLRSNIVYAIKRLKARQLQSPRLFNYSIDSNLFTVI
                     LDELLYIQTTPGISGTLELHAEREIATFPGNLKEVSLQYPTLFRCHRSILLNPTHISKL
                     DTHGRFVYMDNQDKLEVSIRRVSALRQVMMTANKPQSATNDLSNDA"
     CDS             complement(10458..10655)
                     /locus_tag="ctg12_261"
                     /transl_table=11
                     /translation="MIITGDKMARFIGWLGIVFLPVYMLAFALKVIPKVDVIVPLLILT
                     TSSLTFASSKSGKRQGKLKK"
     CDS             complement(11714..11887)
                     /locus_tag="ctg12_262"
                     /transl_table=11
                     /translation="MTNLEDKELSQITGGFAFVIPVAAILGFLASDAWSHADEIASGAK
                     TGWEIANKYKIY"
     CDS             complement(11926..12099)
                     /locus_tag="ctg12_263"
                     /transl_table=11
                     /translation="MQQFMILDNSSLEKIAGGENGGLWSILGLGLGFSARRANSLFGPT
                     PEMALDLISLFK"
     CDS             12421..12645
                     /locus_tag="ctg12_264"
                     /transl_table=11
                     /translation="MNAYKQLKQPLSMWIINCCLVALLFLVPDDSSIFVYIVIDLAIVA
                     NGFDLLKKLFGLSKHADWHHNTWNRDESK"
     CDS             complement(12677..12847)
                     /locus_tag="ctg12_265"
                     /transl_table=11
                     /translation="MSNFLVGGGFLLAVVWLILSDLDLLPHISFIDRYYLIFLVIFIVV
                     CEKSQKNKPTN"
     CDS             complement(13446..14258)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_266"
                     /sec_met_domain="Abi (E-value: 5.7e-15, bitscore: 50.1,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKRQRLFTPGLRVLYIFILDEFIEAFVFTPFLNFLQLDFWADI
                     VLYKVLSLVIILGLNLLLLRQKIIFRTSFGWPSWQKFVFWDIVGCLVAWQIFTNRNFLD
                     IFQASVIGTIAAVPEEYLYRGVIFGGLLRAFYLANRGGTKRNFLYCMLLSSLAFSLAHL
                     SNLPSQGAVATVGQMIQVSGMGMLLAALYVRYGTLLMPIFVHFMIDFLVTLIHGPYPSK
                     LNGVSDETTLIIVSVIWAGIYLAISMWTLWHCHDKEGFMARLAGQAIK"
     CDS             complement(14541..14699)
                     /locus_tag="ctg12_267"
                     /transl_table=11
                     /translation="MHRIKNDDLQQMIEGMTWRKFLTMLILGLIAIDAWSHTDQIIAGF
                     LKGWQGM"
     CDS             complement(14815..15147)
                     /locus_tag="ctg12_268"
                     /transl_table=11
                     /translation="MNMIQQNKVYFIMTGLNESFQKTATVSVMNTDAQEVIDDALHILE
                     KENVLQNRAIDYALARLYSRFVRLIGLQGMKLSPEADQWWQQLKDFMENDIHEELSQVG
                     GPHFIT"
     CDS             complement(15399..15584)
                     /locus_tag="ctg12_269"
                     /transl_table=11
                     /translation="MTLNKAIHFLLLIGISGVFLFTLAAAMGWVNQGDFALPLLLLAAG
                     LTLLRETDAGYEKARH"
     CDS             complement(15903..16238)
                     /locus_tag="ctg12_270"
                     /transl_table=11
                     /translation="MTDKRETLMSMLSKAYSSPTIKAEPELRALIETNAKKVDEGDDDK
                     AYVTAVTQLSHDISKYYLIHHAVPEELVAVFNYIKKDVPAADIDAARYRAQALAAGLVA
                     IPIVWGH"
     CDS             complement(16357..16953)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 106.2;
                     E-value: 3e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_271"
                     /sec_met_domain="Mac (E-value: 1.7e-09, bitscore: 32.4,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEEKFAFMATGKPYDDMDPLLLAVRDEATAKTDALNNEHDPAK
                     RNALFRKLVGQTGFKPFVNPNFHCEFGRNIRVGDHFYANYDCTILDGAPVTIGDHVLFG
                     PKVGLYTSNHLFDPLERQLGGCIAKPIVVGDGCWLAANVTVLPGVTIGAGTIIGAGSVV
                     THDIPARVIAAGNPCEVLREITAADKTGFAGHDMV"
     CDS             complement(17224..17532)
                     /locus_tag="ctg12_272"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNPYIVLTTLDGRLDFTFISMSNLKKLKSELMSLEIKSMD"
     CDS             complement(17668..17883)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_273"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 6.8e-09,
                     bitscore: 30.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKTSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(17880..18185)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_274"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1e-13, bitscore:
                     46.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVKDSKVDLTQNNLLLFEEKRKIMSYNYRQLDDFQLSGVSGGKK
                     KFDCAATFVTGITAGIGSGTITGLAGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(18385..19338)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.7; E-value: 5.1e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_275"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             19543..20277
                     /NRPS_PKS="Domain: PKS_KR (6-168). E-value: 1.1e-11. Score:
                     36.7. Matches aSDomain: nrpspksdomains_ctg12_276_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     190.4; E-value: 6.3e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_276"
                     /sec_met_domain="adh_short (E-value: 1.4e-33, bitscore:
                     110.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTVKDKVVVITGASSGIGAATVQVLAKAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALVDLAVGKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTSMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        19561..20046
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_276_PKS_KR.1"
                     /evalue="1.10E-11"
                     /label="ctg12_276_PKS_KR.1"
                     /locus_tag="ctg12_276"
                     /protein_end="168"
                     /protein_start="6"
                     /score="36.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAKAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALVDLAVGKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQ"
     aSModule        19561..20046
                     /domains="nrpspksdomains_ctg12_276_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg12_276"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       19564..19644
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_276_0001"
                     /evalue="5.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg12_276"
                     /protein_end="34"
                     /protein_start="7"
                     /score="12.7"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAKAGAKLVI"
     CDS             20303..21466
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     289.8; E-value: 4.5e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_277"
                     /transl_table=11
                     /translation="MSGFHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANINALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTPAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRNHVAGAFPVIVVGGLKTPADAEKAADSFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     FQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSVTSSNVPQD"
ORIGIN
        1 ttcacagcaa ccatctgata gggatcacca ttttgcagat gttgcgctga tgtgaacaac
       61 aactttcgaa gatcatcctg tttggcaatc tcagggtctg cataagcaac atcgattgct
      121 tcaaacaatt gtgtttcttg ttttttcatg aacgtgtcct ccttacaaat attcaaagcc
      181 aaacgctcaa cccgccacct ccgcgcgctc gcatactagc gcctgctacc aatttataaa
      241 ctggctcaag tgcagacgga tactgaaagt gatgaaactg cgaataagac gcgatgaagc
      301 tgtcaaggcg ggcagcgacg taactgaacc gatcaccact tgccaatcgc tgggctgatt
      361 caaataaaaa acgtttaatc tcatcatcct gctggactgc ggcatcatta taggcgccat
      421 caatggcctg aaataaccgc gtttcctttc cacccaatac gatcagctcc taacgataac
      481 ggcagtttaa cacttcaaaa aatgcggcgc aatgttgata cggatgaccg atcaaccacc
      541 gacatgccaa acataacggc tggttgtaat ttttcaaatt gtcatgtgaa ctgaaccatg
      601 attgactgct gttaccgccc ccaaaacact ggatagctat tgttagtaac cataccgaat
      661 attcgccagg gccatcaatg catcaagctt atccgactct gaaacagtta acacaatctg
      721 gttgtttttt cagagcgctg gaaatgtcga gattcatgcg gctcagaatg aacggaacag
      781 ctgaatcctt ctttctaaac gcctctatat aatcacttaa cacttgttgt aacggcattt
      841 tctgctggct atgatttagg tctgccacca gttcagttaa aatactgatc gcttgttctg
      901 ctcggtcttg accgccagca taccatttta aaatactcat tcttccttca cctcttaaaa
      961 gtctttcgga acacaaaaag gcccatttcg cgccatggta tgacgtgaaa tgggcctttt
     1021 gtgtccaacc aaatgatgct ctcaatcact tttccgccat cgcgaatcca tgattaagcg
     1081 ggccgtaaac agtcccagtg gtaaaaacat gataatcaaa gcggcgcggg tcatccattc
     1141 agcgccaacg ccgatattat ttaagccgat gttataaatc gctcgataaa tatacaagcc
     1201 aggcaccatg atcacaatgg atggcactgt gagcgagatc cgcgggtagc cgtcaattcg
     1261 attgatcgcc gaagcaagta accccgcgac caacgcgcca ataaaagcgg cagccgccgg
     1321 tggaatcgtg ctcaagtcga ccagttcaag tcgcagcgta ttcgccaccg ccccgatcaa
     1381 accagcttgt accgccatgc gctttggact gttaaacatc accgagaaac caaagacgcc
     1441 gctgaaactg gcaatcaacc gaaaaagcag caaaagcatc ggattcaatc ccagatcgac
     1501 aaagttctca ggccgcaagt gcacaatcat cgccactaac cacccgacca gtgatgcgac
     1561 aatcgtaatc atcaaggcat acagcaagcg ctccatcccc gaccgcatat cttgcttcga
     1621 aatatctaac atactcgtga tgaacggaaa accgggaatc acgaacagca tggcaccaat
     1681 ataaccggcc tcatgccgcg cagcgatgcc cagactcatt tctaatccac gaaaaacaag
     1741 gaagtacgct aagcaagcaa cagcaacact gacgccaatg caggccaaca aggtccagct
     1801 gcggcgaatc ataataccac gcaaccaatt gccgataccc gcgccaacaa aacagcaaac
     1861 catctcaact ggaccaccgc caagcagaaa aacgaaagcg caacacgcca gcgccgcagc
     1921 caatcctgct cgcagcggat cataattacc cgacattttc tggatctgat cgagccgatg
     1981 atgaatctcg cgcaccgttt ccgtggtata ttgcttttca aaattgcgta caaaccgttc
     2041 aagtgcatca agtttatctg tgttcacgcc gctttgcgat aatgagagaa cttcggagta
     2101 ggcgtggttg ttactaaaac aagtgtagga taacgaaatg aggccaatat cagcagaaca
     2161 cgacattcgc aaagcacgcg caaccgtgtt catagcttca cgcacgcgcc atgccccagt
     2221 tccacacgcc agcaacataa tccccacccg accaacgagt gaagcacgtt cctcaagcgt
     2281 ggcatgatct gcctgccgtt cttcgctgac aatcacgtca taccatggaa tctgcatgtg
     2341 atgtttttct gaaagtggtc gcgttcctcg cgctgtctga ttactttttg ccgtcataac
     2401 ttgtgccgat ccttcttctt ataggaatgt gttatcttga aaaaatgaaa ataaacattc
     2461 actattttag cacatctgac ttacacgcgt tggcgatcaa accaggcctc gtctcttacc
     2521 ccgacagttt acgctgaaat acggcactca aatgacactt tttaaagcag ctaacacagc
     2581 agctacgaga taacaaatga tatgcccatc attcaaaact taacctcctt cgtctacgcc
     2641 actagccgca aaaatgggtc gggtgcctct aggctagttt tgattaaatc accaacgcgt
     2701 catcaaaccc tagctttctg ttctttaatt agacgcagtt cacgcctcaa ttgacgcaag
     2761 ttgcctagcc acaaaaatga aaaatccagt tcaccatttt catcagcaaa taccatataa
     2821 ggattttccg gatcaattaa ttggctcatg gctttgcttg ataactgcaa tccttgattc
     2881 agggtcttaa tctcgtgaat caggtgtctg cgaagtattc ttttccaaaa gaccggcacc
     2941 gcgtaacaaa tgacaccgcc catcaccatc aagctcacca tacctgcatc aaccaaagcg
     3001 tctatcttca acaccccaaa cttgtgatcc tgctgccgat caaacgatcg acacgctaag
     3061 cgacaaccag tgtgtttcca atgtttttag ttacagccaa acaaatgggc aaaaaagcgc
     3121 tgcaagccat gccgctccgg ttctggcttg ccaagtggtt ccccgttcgc caaccgtcga
     3181 atgtcatcaa tcgcatctcg ccccaattga ctcaactgga tactttgggt tgacaaaatg
     3241 aaatcaattt tttgggcaaa tctaaacaat tggcgatcaa actccggtcc atgcggcagt
     3301 tcattgtcca tatcaccggc gactctgtca acgacgtacg ccatctccgg cgaccgatta
     3361 agcgggtgta actgatgaat ttcatgacgg agaatcataa tcaattttct ggcttccatt
     3421 tcaagttgat attccatacc cctttacctt tcccttaaca aaagataact cccatcccaa
     3481 ctttaacaag cacttgctta ttgtaagatt accatctccc gcgttgtgtg acgcaatctg
     3541 tcgattaacg tcgtgttttg gccgattaac gtcgtgtttt tcatctttca gcttaaaatg
     3601 agccttaatt ttactggtga ttaaacattt tatcgacaaa atattgccag taagttttcg
     3661 ttcccgtgat aacggcggcc tgtcctgcga taccgtagtg caaggtctgc cgctgtcgtt
     3721 cactcagtgg cactcgggcc tgtactttaa agtaattgcc aactttagca ttcacagttg
     3781 gtgcgacatc aatggcatca atccggccag tcagcgtcat cggtgatggg acattctccg
     3841 caattcgcag tcgaacgctt tgaccacgtt tcaaactcat gatttccgct ggcgaaaccg
     3901 ccagcttcaa ctcagcttct ttttgcgtgg ctaagtctgg caagatttgc gccaaaacgg
     3961 tgccagctgg aatgtacttg ttgccactta aggatgcttc aagatgcaaa acgccgctgg
     4021 cagatgcttt gacttggtaa ttcttacttt cgtcctttag tgccgccagt ttcgcctcgc
     4081 cttcttgggt accttgttgg actttcacct gttctgcagt catggtttgc tgcatatggc
     4141 tttgcaacga ggccagtttt gcctcattct gccccgtctg ctgcgctgaa agatcggcct
     4201 gcttctggtt gatacgttgg gtgcgcaagg aagcgagggt ttccttttcg gttgtcaata
     4261 aactttgcaa ctgtgactgg tactgacctt tcaaactgtt caaattagcg gcatcggcat
     4321 ttttagcctc ggctttatat tgcaaataaa gatagttgta tgcgtgattg tcacttaatg
     4381 ggcgatcggt tcgtatggcc atttgggcct cacgaatcgc cgtcatttta gcctcgcttg
     4441 cttgcatact ggtctgcaac agttgatcga tttctttgct cttaccatcc gccacacctt
     4501 gggtcgcatg caaggcttcc gattccagtt cgtaaacccg acgttggcta agataatcgc
     4561 gaacttgttg ctgatacccg aatttatccg gactcgcaaa aaggttttta ttggcagcaa
     4621 tactctggtt gagaacttcg agctgcgctt tttgatcttt caacgtcgcc agttgctgtt
     4681 caagcacttt caattgtgca ggatgagcaa catcgtgata caccagcaac gtgtcgccgc
     4741 gtttgacatg cttgccttcc ttcatatgat tcgtcacaat tcgattcgcc gccgtccctt
     4801 gaaccgtgac cgccgttttg accggcgcaa tttccgccgc tgttaaaacg gtcacctcgc
     4861 gcttggcgaa gatcagaaaa agcaacaaca gaacaaagag gatcgcggtc ggcacaataa
     4921 tgactgttga aaaattacgg tagcgatggt tataaaactc ggttgtctct aacttcttta
     4981 gatcaatcat cgcggcctcc tcactcactt accaaccgag cataatagcc ttgtttggcc
     5041 aataactcag catgatttcc ttgttcaaca atcgcaccat gatccatgac cacaatctgt
     5101 tccgttttag cagcaatggt cagccgatga gccacaaaaa taatggttcg atcagtcatc
     5161 gctaacaacc gatcaacaat ttttcgctcg gtgatcgtat ctaaactgct ggtcgattca
     5221 tcaaaaatta acacttttgc cggtgataat aacgcgcggg caattgctag gcgctgcttt
     5281 tgtccacccg ataaaatact gccgctttca gaaagtttgg tctgccatat ctgcggcaaa
     5341 ttcgaaatat ctccggcaat ttccgccact gaacaggcag cttcaatatc ggcttcagtg
     5401 atattcgaac ggctacccaa cgttaagttt tcaatgactg agccagaaaa aataaacgga
     5461 tcttgtggta catactcgat atattgtcgt aacgttgtca gatcaacatc actgatggga
     5521 acaccgttaa atgtgatttt ccctttgcca gtgtccactg gatagaaacc tactagcaac
     5581 ttggctaagg tcgatttccc tgatccactc atgccgacaa tggtgtattt ggcattctcc
     5641 gggatttcaa ggttgatttg tttcaaaaca tcttgcccaa aaccatactt aaaggacaca
     5701 tcggtaacat tgatggcgcc atcaattaaa tgccgatcat tcaaacttcg ctgttcttta
     5761 aactccgatt caaccaaata cacttcattc agccggttat tcgcgacttt ggccatttgc
     5821 aattttggtt gcaaattaat gatgctttct aacggattag tgaaatatgc caacaacgca
     5881 ttgaacgtca gcatctgtcc tagactcatc ttgttagcca tcaccaaact cgcaccaatc
     5941 cacagcacga ccacattcaa aaccaacttc agcagtccct tgatcgcctg ctgcagttga
     6001 tcagcttttg tataattgaa cgactttttc aaatacgtga cgaattcacg gtcaacccgt
     6061 tcataactga ctttctcacc ggtcagtgat ttaatcgtct caatcccgtt caaatcctcg
     6121 ataatggatg aactcaatat ggcattgctt tccatcgtct cttgattcag tcgattaaat
     6181 ggccgctgaa aagcgaacac aatcaccaaa taacaaggca cagcaattaa agacaccaag
     6241 aataaggtgg tgttttgaat gcctaacacg atccctaaaa ttaagacaat ccaaatatca
     6301 agaaacaagg tcataattgt gtttgccagc gcatcaataa tcttattagc atcggaaaac
     6361 cgcgacacaa tttccccagt ccgacgcgtg gaaaagaagg acatcggtaa ttcataaaga
     6421 tgcctaacgt aacccaaaat gacatcaatc gacaaacgct gtcctaaaac agccatcaaa
     6481 aaattttgcc cataggttaa aaccgactgc aggacataag cgaggatgag gccactggca
     6541 atcattccca aagttgtgcg catcccgttt ggaatataag tatcaataat cgactgaaga
     6601 aaataagacc cgacaatact aatcaacgtg atcaacacag cggcgacaat aatattggca
     6661 atgattcctt tttgtcgcgc tagtatcggc acaaacgcaa agagactgcc tttgtcctct
     6721 ttgcgtggtt gatattgcgg ttctggcgca ataaaaatag cgacccccga ccactccttc
     6781 gcaaagcgct ctttgggaag ccaggtcatc gctactgatg aatcaggatc gccaatcaag
     6841 atatgatcct ttgtcgcctt aaacacgacg taataatgaa gcaactcgcc acgcttcaaa
     6901 acatggacaa gaaacggata aggaacatca tcaagatcaa acagcgtcat atccgccttg
     6961 acagccttgg tttcaaaatg aagcgcctga gcagcgcgga caatccctaa cgctgttgtt
     7021 ccttcctgat ccgtcttcgc caactgtcgc agatgcgcta gcgaataatc cgagccatta
     7081 aattgcagca gcatattaag cgccgcaacc ccgcaatcgc gctcatccac ctgaggcgtg
     7141 tagtaacgct tgtaatactg tgcttggccg agctttaggt tgtatttgat catgggcatg
     7201 cctcctggtt ggtgctggat ttttctaaat aagtgatacc ttgaactgtt taaaaaatgg
     7261 gttgtcgtta tgacaaccct taaccttaca gaggagaaga ctgtcccaga agccactaat
     7321 cagtcaaatt ctgcgaaggc ttgtggaaca ccattttctc tgtaaaagcg tttaacataa
     7381 aacttaaaat ccaagaaaat tgtgcaaagc atgaaattgt ttagaaaaga tatgatatac
     7441 tgtcaccgat aacgtggtac ccgctttaat aatatataaa gctattttta catattatta
     7501 tcatagcaat ataatctttt aattaaacaa atgatcaata atctaattct tttgttttaa
     7561 agagctgcca gaagaaggtt ggttaccggt cttaccttta tgtcatctac cttaatgatt
     7621 tagatgggag cgaaaactcg taaacacgat ttccctgatt tatttaaaca agccatcaaa
     7681 ccatcttctt attttgttga atgttggcga aacatcacgg atgctgtcac ctccaatgaa
     7741 tcccaaaagt tcttcgtcac tcatattgac cattttctgc tcatcaaact gtttcatttc
     7801 tttttcctcc tcattcaagt tgaagtgttc ttttgcttta catgaattca atgtaacaga
     7861 cttttggctt gttcttgttt tccaaaaata aacgtagggt tttcgccgat taacgtcgct
     7921 tctacgtctc ttcttagttt gttacaatga ttttttaacc ctattcagca ttcagaggtc
     7981 aactccatgg aaacttattc tgatctagcc tatattcttt taacatcacc cgtgttcatc
     8041 ctaggcataa cgtttctgtc atatattttt ttcaaccgaa ttaatctcat tcacattttt
     8101 ttttggtcca tcttagcgat ggtgttgtct acaacactat cgctacttgg tgaaatcctc
     8161 tttggattga tctatgccta ctacatgtca aaaactcata accgatctga tgtattctgg
     8221 gttttcctat ttttggaaat caacttgatt attgtcaatt ttcaaacact actggaaaag
     8281 tccttcacgt tatcaatgac caataacttt ttctttataa gcataacgtc taaattaatc
     8341 accaatatca tactgctcat attggctatt tggttgtttg gtacgaggaa aaaaattgtc
     8401 aataatatgc gtcatttggt tcaagaaaaa gatggtattt ggatgtcggc tatcttttac
     8461 ctaggtgcct cttggactgt catgtacttc ctagagttta cctttatact cctaaagctt
     8521 gataatgttc ttgctctact catactatct gccttcattt ttttcatggt tgtcaattta
     8581 tgctctctat tttttatttt gagatcttac cgatactatc ttgagctact ggtcgttaaa
     8641 cacaccaatg aatcacgacg agcttactat gcatcactta accaacaaag ggaaaatact
     8701 agcaagcttc ttcatgatta taagaaccta ctagcaacgc tccaactttc attgcaacaa
     8761 acttcagcaa gtcaatcttc tgacacgagc aatatcatcg cgcaagctca aaggtcaata
     8821 caacaagctg aaagtggcaa ggactcatta gcagcaatcg aaagtgatcc gcttcgaaat
     8881 ctcctctatt tgaagtggtc agaagcgacg aatagtggta ttagattaca catccacacc
     8941 gaaggaacaa tccaaccgct gagtaataat gccggttttg ccgtcatcag agcacttggt
     9001 atcttaatcg ataacgcctt agaagaatct atcaggatta acaagactca tttcagcgtc
     9061 ctgctagtgg cttcagatcg ggggctagaa gcaagcgtcg ttaacgatat caatgatgat
     9121 tttaatctag caaaatttgc agaacctggt ttcacaacca aaggccgcgg gcacggcaat
     9181 ggcttgacca tcataaatga gttaattcag cagaataaaa atatcatcat taaaaagacc
     9241 gttattaaca agcaactaaa gatcactttg tttataggga gatgacttca tgaccaacca
     9301 ccaaacgatg ctgaagattt tcattttgga agacaatgct gacttcttga atttcctaga
     9361 aagtacactt cgcaattata ttatgattga ggcattgcat gccgaaatca aattcaccac
     9421 tcagtcagcg acagatttgt tagatgctgt tgatctagaa gagattaatg actgcctttt
     9481 tctgctggac attgacatcc ctggatcttc tgtaagtggt attgatatcg ccaccatcct
     9541 tcgaaaaaag tccttatacg ctgacatcat gttcatcacc agtcacactg aagaagcctt
     9601 gtcgattctg gcccacaaaa ttgcgctttt agacttaatt gataaaagtg tcctttttga
     9661 agttgaagcg cgactgcgat caaatattgt ttatgccatc aagcgtttga aggcgcgtca
     9721 attgcaatcg ccacgacttt ttaattacag cattgattca aatcttttta cggttatatt
     9781 agatgagcta ctttacattc aaacaacccc tggtatctct ggcacgttgg aactacatgc
     9841 agaacgcgaa atcgcaacct ttccgggaaa cttgaaggag gtatcgctcc aatacccaac
     9901 attgtttcgc tgtcatcgaa gcattttgct caacccaacg catatttcta aattggacac
     9961 gcatggccgt tttgtttaca tggataatca agacaaactt gaggtcagca ttcgtagagt
    10021 atcggccctg cgtcaggtca tgatgaccgc gaataaacca cagtctgcta ccaatgatct
    10081 gtcaaatgat gcttgaatgg tatatctctt ttttcgcgtc tccactagaa gcgaatctaa
    10141 acggtgatga aaataaaggt cacttgaaaa aactccaata ttcccataac ctggcagaaa
    10201 tatcaaagtt tctagtaact gtttcattta actgctgaat acgacaacag attcagtgtt
    10261 gtttcctctg aatctcttac agcagtgctt actcattaat gctgtttaat tttgagatat
    10321 aaatacacct tagtccagct gattagttca tgagaaacag gcgctgcaat caaaaactgt
    10381 ttcagtcctt gattgcagcg cctgtctatt tgatgacacc tttagaataa cttttaagaa
    10441 gcgacagatt ctcaaaccta tttctttaac ttgccctgtc tcttgcccga ttttgaagaa
    10501 gcaaaagtca aagaagaagt tgttaatatt aacaacggga cgataacgtc aactttagga
    10561 atcaccttta atgcaaaggc aagcatgtac acgggtaaaa aaacaatacc gagccatcca
    10621 ataaatcttg ccattttatc tccagttatg atcatgttga cctcctgatt aactatttaa
    10681 gcgactgccc actttcccag ctggtagcca aagctcaata tcatgcttca atgcctttta
    10741 acaccatgcc aagtaacaag tccactaatt ttcagtacct gcttagctac cttacacaca
    10801 gtatacgtcc gacaaattgt tctgtggtcc taaaattttt aacgttggta atttaaagtt
    10861 tttcgttaat tcttttaaaa aaagtgcaaa agtactgcgg aatagacaat tttgcgacgt
    10921 ttacttcttc ggtttttaaa ctagtttatg atagacaagg catcgacaaa attcctaatt
    10981 ttgtctacgt tgcactagaa ataaatccgc attatcacaa cctaatctct tgttatctgt
    11041 tacactcttt cttcgaatgg gcgtaataag gatcaatcaa taaaagaatt aggcgtgcta
    11101 taaccacatc gcatccagtt aataagtgcc tataaaatga ctaccacaaa aatacctcca
    11161 actttcttga taaatcaaga aagttggagg ttgtctggat tttgaaaatg gaactaattg
    11221 ctgcctcaaa aatgaacttc ggtaaacatc ccatgagcag gcacttcaat aaaagatcca
    11281 aaattgtctt tcacgtttgt cgatcaacca aacatgtgac aaagaataaa cttaaattga
    11341 agcatctatt tgagacgccg agctatctct ggtcactgct aatcgaagtt aaaatgattg
    11401 aagtaactaa agcaatggcg cagataccga caatcttgtg acaactttta agagatatat
    11461 ggtatcgata ggcagtagta cgcataggta cgatgctcac tatcagcaaa tttcttcgta
    11521 cgctatcgcc atgtgcaagc taggtcatca tattgataaa ccaaaatagt atacaaagtt
    11581 gaaaaaatct catcaagttg gtcgatgtcg tcatccttga gtatatcaag caactattct
    11641 taaggatcag ttcttgggat cagctttcga atgagacgag attgctgggc agttctacga
    11701 atcgattggc aaatcaataa attttgtact tgttagcgat ttcccagcca gttttggcac
    11761 cactagcaat ttcatctgcg tgactccacg catctgatgc taggaatcct agaatggcgg
    11821 ccactgggat cacaaacgca aagccaccag tgatctggct aagttcttta tcttctaagt
    11881 tagtcattgt gcacatcctc cttttgctgt ttagctagga ctgtattatt tgaataggct
    11941 gataagatct aaggccattt ctggagtagg cccaaacaaa ctattagcgc gccgtgcgga
    12001 gaatccaaga ccgagaccaa ggattgacca taaaccgccg ttttcgccac cagcaatctt
    12061 ttccaagctg ctgttatcta aaatcatgaa ttgttgcatt gttatccctc cattttcttt
    12121 gagtgattca ttgctaaaca tttggttctt aggtaaaact gtcgggggtg ctagctaccc
    12181 tacacacaat atacggctag caattgcttt tgtggcgact taaattttaa cgttgatatt
    12241 ttcaattttt ttgtccgttc tatcttcaaa aaatctaaaa tacgacgaaa aaaggggatt
    12301 ttacgacgtt tattttttga tgacccattt ttcttgaaca ctagttatta tgagtatgaa
    12361 atgatgtaat gatactgaaa gtttaaagat actgagcata acccaatgga gatgactttc
    12421 atgaatgctt acaagcagtt gaaacaacca ctgtcaatgt ggatcattaa ttgttgctta
    12481 gtggcgttgc tctttcttgt tcccgatgat tcaagtatct ttgtctatat cgtgattgac
    12541 ctcgcaatcg ttgctaacgg ttttgattta ttaaagaaac tatttggtct gtcaaagcat
    12601 gcggactggc accacaacac ttggaatcgt gatgaatcaa aataaaccta caaactaagc
    12661 gtcgcctcga catcgcttaa tttgtgggct tgtttttttg actcttttca cacaccacaa
    12721 taaaaataac gagaaagatc aaatagtagc gatcaataaa tgaaatgtga ggtaacaaat
    12781 ctagatcact taaaatcagc caaactacag caagtaaaaa gccgccacca acaagaaagt
    12841 tgctcatttt tctaaaactc ataaacagac ccactctcta ttattcttca atgtttattt
    12901 ttgcaataat acaaacggtt catttgccaa ttgaggagat taaatgcata tagacatcat
    12961 gatctgcgca cttgaattat ctgtttaaca gttgcaataa caccttggta tggcaaagtg
    13021 tttaagtgtg cacgagaaaa cgaaagtcat attcacagat gaaaatcatt tagagtttcc
    13081 ttttttgaat aaatcactcc tcaaaaaatc gaatacagac accaaaagag acgagcttat
    13141 catgctcgct atgaaggtaa acaatatcac gaatatgata acgaatctca ttgtattgtt
    13201 agtgctaact tgataaatca tagaaacgaa ttcttttgga tttataatcc tgtacagaat
    13261 actgagtatc attacctgta ttgctgacaa agcaaggatc ataatcattc tttgactttt
    13321 tttagatttg gtcacttgat tcagctcctc ttttttggat tttcctataa ttaaataagc
    13381 gattagcata tccagtaata aagttttccg caattgcgag tgaaggtgtc caagatacta
    13441 taaacttatt tgattgcttg gcctgctaac cttgccatga acccttcttt gtcatgacag
    13501 tgccataggg tccacatgga aatggccaag taaatgccag cccagatcac cgaaacgatt
    13561 atgagcgtcg tttcgtcact taccccattt aatttgctgg gataagggcc gtgaatcagc
    13621 gttaccaaga agtcgatcat gaaatgaaca aaaatcggca tcagcaatgt gccataacga
    13681 acgtagagag cagccagcag catgcccatc ccgctgactt gaatcatctg acccacagtt
    13741 gcaacagcac cttggcttgg cagattactc aagtgtgcaa gcgaaaacgc cagactgctt
    13801 agtaacatgc aatagagaaa gttacgtttg gtaccaccac ggttagcaag gtaaaaggcg
    13861 cggagcaatc caccgaaaat aaccccgcga tataggtact cttcaggaac agcggcgatg
    13921 gtaccaatga cacttgcttg gaaaatatct aagaagtttc gattggtaaa gatttgccaa
    13981 gccacaaggc agcccacaat atcccagaac acaaatttct gccagcttgg ccagccaaat
    14041 gacgtcctaa agataatttt ttgtcttaac agcaacagat tgagccccag aatgataact
    14101 aaactaagta ctttatagag cacaatgtct gcccaaaaat ccagctgtag aaaattcaaa
    14161 aatggggtga acacaaatgc ttctataaat tcatccaaga taaaaatgta taaaacccgt
    14221 aatccaggcg tgaacaaccg ttgccgtttc ttttccattc cgtcaccttc atccaagttg
    14281 acaaagccgg ctttttccga cattgctatg aacaatatac cggttaatga atggctttta
    14341 gtcaactaat tttaaacgtc gtgttttcac catttaacgt tgacgatcat ccgtcaaaaa
    14401 ttcgctagcg gtcatttgtt gacaaaaaag ccacttcact cggcaaacga cgctacgcta
    14461 agccaagaag aagtgacgct gcagtgttga aaaagtcgcg gagcttgcaa ttggcgcaat
    14521 tcttcaccgg ccacaaacac ctacatgccc tgccatcctt ttaaaaaccc cgcaataatt
    14581 tggtcagtgt gtgaccaagc atctatcgca atcaatccta aaatcagcat tgtcaggaat
    14641 ttacgccagg tcatcccttc aatcatttgt tgcaaatcat cattctttat tcgatgcatc
    14701 tcatcgtgct ccttccccaa ccagtctaaa taaagtggta agtcacagga taaacagcgt
    14761 aacactcgac ttccgacttc gcatttgcgt gtgccaatat tggcaacaaa ccgatcaagt
    14821 aataaagtgc ggtccgccaa cctgactcag ctcttcatga atatcattct ccatgaaatc
    14881 tttcagttgt tgccaccatt gatcagcttc cggcgataat ttcatcccct gcaacccaat
    14941 taagcgaacg aaccgagaat acaggcgcgc taatgcgtaa tcaatggctc tattttgaag
    15001 cacattttct ttttccaaaa tgtgtagcgc atcatcaatg acctcttgtg catcggtatt
    15061 catgacactg acggttgcag ttttttgaaa gctttcgttg agccctgtca taataaaata
    15121 gactttattt tgctgaatca tgttcatgat atgtcaccat tgcctttgat gtcgtgacaa
    15181 tttttctata gaaatgtttg aaaagtatcg atgctatggc ttttaggcaa agcaccggaa
    15241 aacaatggct ttatagcccg actgatggat cttgataccg tcttgtattt gaactctttt
    15301 agatatgagt catcgtaacc gattacattt taaaatcagt ttgtccttgt gtacagaaat
    15361 tcggcttcac gtttttctac cttctaagca gacccaattc aatgcctcgc tttttcatat
    15421 ccggcatcag tttcccgcaa caacgtgagt cctgccgcca aaagcagtag tggcagcgca
    15481 aagtcacctt ggttgaccca gcccatggcg gcagccagcg taaaaagaaa gacaccactg
    15541 atgcctatca gtaaaagaaa atgaattgct ttattcaacg tcatcgccaa cttgtatccc
    15601 cccgtccaga tgaacttcga ctttttctcg cggatgcttt tacgcacact atactggata
    15661 gttcacacaa cagcgcaaac ttttttaaac gtagggtttt gcccgattaa cgtcgctttt
    15721 ttgtcaaata tcgaccaaat tttctcttta tcgatctgct actcggtttt tttagccgat
    15781 gtcaacaagt ttcatggcaa aaaaaatagc cgcagatctt agtctgcgac gtttttgaca
    15841 aatcataact gattgatcat caactttagc ctcaccgttt aaaattcaca gttgtacatc
    15901 ggctaatgcc cccaaacaat gggaatggca actaagccag cggccaaggc ttgcgcgcga
    15961 taacgtgctg catcaatatc ggcagcaggt acatcttttt tgatataatt gaaaacggcc
    16021 accagctctt ctggtacggc gtgatgaatc agatagtatt tggaaatgtc gtgggacaac
    16081 tgagtgacag ccgtcacata agccttatcg tcatcacctt catcaacctt tttggcattg
    16141 gtttcaataa gcgcccgcaa ttccggctct gctttgatcg tcggacttga gtatgccttg
    16201 cttaacatcg acattaaagt ttcacgttta tctgtcatcc tgcacttcct ttcgatgatt
    16261 aacttggcaa ttcatgctca ctcagagcac tttagtcatt gtgaatattg ttagaatgcg
    16321 cttgtcaatt gccattttca agtatcaatt cagcgtttag accatgtcat gtcctgcaaa
    16381 ccctgtttta tcagcagccg tgatctcgcg gagcacttcg caaggattac ccgccgcaat
    16441 cacgcgcgct gggatgtcgt gggtgacaac actacctgcc ccgataatcg tccccgcacc
    16501 aatcgtgacg cctggtagca ccgtcacatt ggcagcgagc caacagccat ccccgactac
    16561 aatcggttta gcaatacagc caccaagttg tcgttcaagc ggatcaaaaa gatggttgct
    16621 ggtgtacaaa ccgactttcg ggccaaacaa aacgtgatcg ccaatggtca ccggcgcccc
    16681 gtccaaaatg gtacagtcat aattggcata aaaatgatcg cctacgcgga tattccgacc
    16741 aaattcacag tgaaagtttg ggtttacaaa cggtttgaag ccagtttggc ctaccaattt
    16801 cctaaacaag gcattgcgtt tggctggatc gtgttcattg ttaagtgcat cagttttggc
    16861 agttgcttca tcccgcacag caagcaacaa aggatccatg tcgtcgtatg gcttaccagt
    16921 tgccatgaaa gcaaattttt cttctagatt cattgcgcca cccctctttc ttggctcaag
    16981 tttaccagac atttgcgcac tgcgttgata attgccaata tgttaaggtg tgcttatcgg
    17041 tacgcatgaa gtctacaaaa agccaccact tcttgaagaa atggtggctt gaaaacaatg
    17101 acatcgcttc tgcacacaga accacgcctg ttttgttaca aacagaaaca tacagttaca
    17161 gtcttcatcg tcacaaaatt ctggcgttag gaaatttcag ctacttcctc ggactttatc
    17221 agcttaatcc atagacttaa tctcaagtga cattaactca gattttagct tttttaaatt
    17281 tgacatagag ataaatgtaa agtcaagtct tccatctaga gtagtgagaa ctatataagg
    17341 gttctgggga ttgattaacc tactcagccc cttactagat agtttcaaat cccgatttaa
    17401 caaaagtatc ttggcaatga ctttgcttct tgctgcccct tgccaaagtc ctccaacaaa
    17461 tggtgctaga taaaaagcga tcgtcgccag taaaatcaag ataactatga tgatacttat
    17521 tatcttatcc atttgtattt cctcttcctt ttgcacaaat agactaattt gaaatcgatc
    17581 tttgactaag acaagaaaaa gtgagcacta ccaaggtgtt agttatattg aacagttgcg
    17641 ataggagcta accgtctttg tccaatatta ggctgggtga atgtaattag tgctgagaca
    17701 caaggataat cctattgcag cgcctgcaac agttgtaaat ggatttaatc cagctgcccc
    17761 tgctaccgct cccccgatcg tggacacaat acacccacta gttttattgc gtcgcttggc
    17821 tcctccttgg attaagacca aatcatgctg ttttaaagta atgcccactt ctttacttat
    17881 cattgcatcc catctcctaa gcatttaata gctgacccaa ccgctcctaa gtttccacca
    17941 actacggcgc cgccgattat cccaaaagga ccaccagcta ggccagtaat cgttcctgat
    18001 ccaataccag ccgtgatgcc agtaacaaat gtagcagcac aatcaaattt ctttttccca
    18061 cctgaaaccc ctgacaactg aaaatcgtcg agctggcgat aattataaga cataattttt
    18121 cttttttctt caaaaagcaa caagttattt tgtgtaaggt cgactttact gtctttaaca
    18181 tacattaatt atttgtgtaa aatgccaaaa ttttttaaac gtaggaaatt tccagtttaa
    18241 cgtcgtcttt acacttttat tgttcagttg cgctttaaaa gtcaaaaatt cttaacgttt
    18301 aaatctcctt gcttggtaaa aacttcaatt ttttgcaaaa aaaatcgtct cagcaatttg
    18361 agacaatttt ttcatatcat caacttacgg caaatcattc cccgccgcaa agtaaatgtc
    18421 ataccattct tgtcgggtca acgtgatgtc cgcgccttcc gcactttcct tgatatgttc
    18481 aggattcata gagccgagaa tcacctgcac accaactgga tggcgtaata gccaagcgac
    18541 tgcgattgca tttttattgg tgtggtagtg gtcagcgact ttctgcagtt catcattcaa
    18601 cgccttaaac ttcgggctat cgataaaggt gccttcaaac atgccgtatt ggaatggtga
    18661 ccatgcttgt aaggtcatgt gtttgcgttg caagtatggt aataggctgc catcatgatc
    18721 gaccgaggca gcgtcggcca tgttggtgtg catccccgca ttgaccatgc cagtatgggc
    18781 aacggagaat tgaacttggt caatcagcaa aggctgccga atgccgcttt caagcaacgc
    18841 aatttgttca gggttaaagt tggagacgcc aaaatgccga accttgccac tttgttccaa
    18901 tgcatcaaag gccgccgcaa cgtcatcgac ttccattaac ggatctggcc gatgcagcaa
    18961 gaccgaatca aggtaatcaa cctgcaaccg tttcaaaatg tgatcaaccg ctgacagtaa
    19021 gtgatctttt gaaaagtcgt accgtttgcc gaataccaaa ctgccatgag agcgttttgg
    19081 atcaacgacg atcccgactt tcgattgaat gaataactga tcgcgggaaa cgctggcttg
    19141 cttcaaggct tcaccaaaaa cttcttcgga tttgccttgg ccataaatgt cggctgagtc
    19201 gataaagttg atgccgtcat tgtatgcact atccagcaca ttggccgctt tgtcgggggc
    19261 cagcacattc atccgcatga tgcccaaagc cacacttgac gcctgccaat tggatccgcc
    19321 taatcgaact tgtttcataa acacaaaact cccttcgata cgtcatttca aattatgtta
    19381 ctgacgacaa gtcaagtgta gcccctaaag tctacttgag gtcaagccaa tattagaatt
    19441 tcaataaaac agcttgcatg gtgctgagct gcgcggtagg ttaacctgtg tctgttactt
    19501 attttttctc agcaggataa gcccataaag gaggccgtga ttttgacagt taaagataaa
    19561 gtggttgtaa tcacaggtgc atcgagcggg attggcgcgg caacggtaca agtgttggcc
    19621 aaggctggtg caaaactagt catcggtgcg cggcgcacag aacggttggc tgaattggcg
    19681 gccagcttta cggacggtca ggtgctgtat caacaaaccg atgtgaccga ccagcagcag
    19741 gtgaaggcat tggttgattt ggcagtgggg aagttcgggc atgtggacgt tttgtataac
    19801 aacgctggcc tgatgccact ttctgaaatg gccgaactca aagtcaacga atgggaacgt
    19861 atgattgacg tcaacattaa aggcgtcttg tatgggatcg ccgcggtttt accgcctatg
    19921 attgcccaac acagtggcca aattatcaca acagactcag ttgccggtca cattgttcac
    19981 cctggaaccg ccgtttactc cggtaccaag tgggctatcc aggcgatcat ggacggccta
    20041 cgacaagaac aagcggctaa tcatattaaa acgagcatga tctcgcccgg tgccgtgaat
    20101 actgagcttt tcagcacaat taccgatcct aagcgccgtg aagctgttga agccgatgaa
    20161 aaaaacaatg gcctcagcgc ctcggatgtt gccaaggcag ttttgtatgc cattgatcaa
    20221 ccggccaatg ttgccatcaa tgaagtgctc ttacggccag tcacgcaaga acgttaattt
    20281 tcgtctaaag gagtgtgatt gcatgtcggg ttttcatttt ttaaaaccgt tcaccttcaa
    20341 gcaccaaacc atcacgttga aaaatcgcat tgtcatccca ccgatgacaa cgcgcctgtc
    20401 gtttgaagac ggcactgtga cgcgggacga aatcaggtat taccagcaac gggccggtgg
    20461 cgtcggcatg tttattaccg gtaccgccaa tatcaatgcg cttggcaaag gattcgaagg
    20521 tgagctaagt gtcgctgatg atcgattcat ccccggtttg agcaaactag ccgctgcgat
    20581 gaaaacaggc ggcaccaagg ctattttgca aatcttcagc gctggccgca tgagcaatag
    20641 caagattctg cgcggtgagc agccagtcag tgccagtgcg gttgctgcgc cacgggcggg
    20701 ttacgaaaca ccgcgcgcat tgacaccggc agaaattgag gccactattc acgattttgg
    20761 tcaggctgtg cgccgcgcca tccttgctgg ttttgatggc atcgaactgc atggtgccaa
    20821 cacctatctg atacagcaat tctattcgcc aaactctaat cgccgaaccg atgaatgggg
    20881 cggtgaccgc gataagcgga tgcgttttcc gttggcagtc gttcatgaag cagaaaaagt
    20941 gattgccaca attgctgacc ggccattttt gttaggctac cgcatttcgc cggaagagtt
    21001 ggaacagcct ggcattacct tggatgatac cttggcctta atcgacgctt tgaaacaaac
    21061 caagattgat tacctgcacg tctcccaaag tgacgtttgg cgaacctcat tgcgcaaccc
    21121 tgaggacaca gccatcatga atgaacaaat tcgtaaccac gtcgccggtg cttttccagt
    21181 gattgtggtc ggtggtctga aaacgccagc cgatgctgag aaagcggctg attcctttga
    21241 cttggtcgcc attggtcacg aaatgattcg cgagccgcac tgggttcaga aggtcttaga
    21301 ccatgacgaa aaggcgatcc gtttccagat cgcccctgct gatcttgaag aacttggcat
    21361 tgcgccgacc ttcctcgatt ttatcgaaag tatttccggt ggggcaaaag gtgtcccgtt
    21421 aacaactgcg cagtctgtga catcaagcaa cgtgcctcaa gattaatcta gcatttcaaa
    21481 tcatcgtgcg agtcgagctg taaaaagctc ggcttttttc ttgccgtctt caacttacgc
    21541 gatggtgcct gaagctacca gtgatttata agttttaaat caaggtgtga tcatcacctg
    21601 ctcacgctct gatttaaacg cgttcaccag cgcagaaatc tgcgtataag gacctcaagt
    21661 gtcatggcca agcccaggcc atgacacttg aggccactta tgttccggtt tctaaacggg
    21721 ctggttcacg ctctgactta aacgcgttcg ctggcgcagc tcggctatgc gaaggacagt
    21781 gacacagatg gtcaaagccc gaccatttag gtttcaggcc acttatgttc cggtttctaa
    21841 acgcgcgagc tcacgctctg acttaaacgc gttcgctggc gcagctcggc tatgcgaaga
    21901 acagtgacac agatggtcca aagcccagac catctgtgtc actgccactt cgctacgccg
    21961 agctaaccgc gccagttcac gctcttgtca tttttaacgg gtcgacccat ttatcaaact
    22021 gcgctgctgt gacgtcgccg cttttgatgg cggctgcttt tagatcgagg ttttcttgct
    22081 cagccaattg cgcgatggcg gcactttttt cgtagccgat gtggggtgcg agggcggtga
    22141 ccagcatgag cgaatgatca acgagtgctc tcatatgcgg tgcgtggatg gtcaagccgg
    22201 cagctaattt ttcagtgaaa ctcgtgactg ttttggttag tagatcagct gactctaaaa
    22261 aggtactgat gataaccggc ttgtagacgt tcaattcaaa attgccttgt gacgcggcca
    22321 ccgtgatcgt cgtatcgttg cccatgactc gaacagcggc catggttagc gcttcggcct
    22381 gtgtgggatt cactttgccc ggcatgatgg aactaccagg ctcattggcc ggaatgcgca
    22441 actcaccgta tccagcacgt ggaccactgg caaggaagcg aatgtcattg gcgattttaa
    22501 gcagatcagc cgctagcgtt ttaatggcac catgaacaac gctaatttct gagtgagccg
    22561 ctaaagcagc aaacttattg gttttcgccg aaagtggtaa ttgataaaca tcgctcaatc
    22621 ggcccgccac aatcttgcca aaattagggt cagcgttaag ccccgttccg actgctgttc
    22681 cgccaatggc taagtaaaaa agattgggct gaagctgctt taaagcaatc tgatcatgct
    22741 ccatcatgac cacccatccg ctgatttctt ggccaaacgt tagcggcgtt gcatcctgta
    22801 aatgagttcg accgatttta acaacacgag cgtaagtgac ggcttttgaa tataaaacac
    22861 tgcacagttg gttgacagcg tgcaacaact gattcactgc aatagccgcc gtaatattca
    22921 tcacagttgg aaaagtatca ttggagcttt gactgtgatt cacatcatca ttcggtaaga
    22981 tcggcaagtc ggggttgagt tttgcagctt ggtggctaat gacttcgttc acattcatat
    23041 ttgtttgtgt gccagacccg gtttgataga catgcagtgg aaaatctttt tgcagttttt
    23101 cgtctggcaa ggccaacaag gcatcgactg ctcgcgtgat taattggcct tttggtgccg
    23161 gtaaaacatc agcggccaca tttgc
//
