LOCUS       c00004_CAJJWF0..       14722 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CAJJWF010000004.1 TPA_asm: Lactobacillus crispatus isolate
            SRR341660-bin.2 genome assembly, contig:
            NODE_30_length_108790_cov_14.2692, whole genome shotgun sequence.
ACCESSION   CAJJWF010000004
VERSION     CAJJWF010000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-20 21:24:04
            Original ID  :: CAJJWF010000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14722
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14722
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2187:4722]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2188..4722
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..14722
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14722
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(46..177)
                     /locus_tag="ctg4_1"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHERL"
     CDS             complement(179..340)
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             complement(356..1522)
                     /locus_tag="ctg4_3"
                     /transl_table=11
                     /translation="MELKKNKNNLKQITALIQYAFLKNNDLTKDENFMSRYDHSTGYGY
                     FDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQLMKEILHDLHRQD
                     IPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIVRGKWDNLAVQNG
                     VIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERPISYLIYRIRDNT
                     FLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPEQNELQVDLRPYM
                     MSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRKVAVERKEDALVD
                     FSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDYF"
     CDS             complement(1638..2174)
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDIKMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             complement(2188..3090)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_5"
                     /sec_met_domain="OTCace (E-value: 1.6e-48, bitscore: 157.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 8.3e-20, bitscore:
                     64.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGFNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     NDQLIFMHCLPAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGIPVIVKDGHLRGVAGVIDKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAVGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIVYN"
     CDS             complement(3051..3482)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_6"
                     /sec_met_domain="OTCace_N (E-value: 2.2e-37, bitscore:
                     121.1, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIGYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             complement(3493..4722)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_7"
                     /sec_met_domain="Amidinotransf (E-value: 1.6e-108,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             complement(4796..5644)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_8"
                     /sec_met_domain="LysR_substrate (E-value: 2.8e-29,
                     bitscore: 94.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.3e-23, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             5773..8046
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTNLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGEVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(8517..8846)
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MAILGTITKKDLSRIGSYASAALIGLIVAMLANLFLHNPIIDYVF
                     SIIAVIIFTILTAWDAQRMKDIYLQYGDDLSTNGLAVLGALQLYLDFVNLFLQFLDIFG
                     ANEDK"
     CDS             9295..10389
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MTMRSLGLSIYPGHSKFEGNAHYLDLAHKYGFSRIFMSMLEVQGS
                     PEETKAKYKKIIEYGNKLGFQTFLDVNPAIFKQLGVSYDDLKFFADIGAAGIRLDTTFD
                     GAIEAMLSYNPYGLIIELNMSNNVDYLNNIISYQANTPFIYGCHNFYPQRGTGLPYDFF
                     IACSERFKKFGIHSAAFVSSQVGQMGPWNVEDGLPTLEQDRNLPIDVQAMHLWASGLID
                     DVIIGNAYASEAELKALSKVNRYQLMLHVNYVTDVNKIEKTIVEAPQHFRRGDITKDII
                     RSTMPRVTYADIPNPVHDNNVEFQRGDIIIGNDNFGHYKNELQIVLEPHKESRMNKVGS
                     IRSDELFLLDFIKPWSKFKLIGNK"
     CDS             complement(10433..11752)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_12"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.7e-60, bitscore:
                     195.0, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 7.4e-27, bitscore:
                     86.6, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNVKNIIIGFGKGGKTLAKFLAQKGEEVLVVEKSDKMYGGTCIN
                     IACLPSKRLIIEADNGVDFVDAVNGKNDMTSMLRNKNYHMLADEENVTVLNGTAKFINN
                     HEIAVTTVNGQIEEFHGDRIFINTGALPVMLPIPGLMESNAILDSTAAMDQTNLPKKLV
                     IIGAGYIGLEFASMFAEYGSEVTVLDLHDNFLPREDDDIAVEIKHDLENSGVKFELGVK
                     ISRIDDHTVYYEKDGVTTTTVADRILVATGRKPNTEDLGIENTDIELNDRGTIMVDDYL
                     RTNVENVWAIGDVKGGPQFTYISLDDFRIIKDQLYGDAQRRVSNRINVPYSVFITPTLS
                     RVGLNEKEAKSQNIKYELKKLPVTAIPKAQVLKDPRGLFKALINPANNQILGVTLYGAE
                     SYELINQISMAMKMKIPANILRDQIYTHPTMSESFNDLFK"
     CDS             12162..12275
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MKHKSLITTLAAIMLIGSVGTVTTATSQPVLAISKHS"
     CDS             complement(12538..13134)
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="VITDLRQEFKVSLNYVLAAIAEHPELPIIARSSYYKIIRRQPVKP
                     KRSKLIARIHEIFNHHQGRYGYRRVALQLIRKGWKVTEKTVRYWMHKLGLKGIRRNKRK
                     YSSYKGTIGKIAPNLIHRDFFAALPNTKRYTDITEFHLNNEKLYLSPILDGCGGDIVSY
                     TISKHPDMDLVMTRLLPKGLTPKEYRSQASINPIF"
     CDS             complement(13140..13421)
                     /locus_tag="ctg4_15"
                     /transl_table=11
                     /translation="MSKFNKEQKIEIYHKWKDENISISQLAKAYRMNLANLDYMLRLID
                     MHGIEILTTKNQSYSKEIQQLKEENLRLRIVNEYVKKLSALDQEDQKK"
     CDS             complement(13541..14068)
                     /locus_tag="ctg4_16"
                     /transl_table=11
                     /translation="MAVDFSKYIASVKDFPNKGIVFRDITPILQDGELYRAATHELAEY
                     AKSKKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVVCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLHGRDKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 taaagaaata aatttaagga atcattcatc cttacacaaa ctattttaca gtctctcatg
       61 actagtcgca agtagtttta catctacatt aggatgtttt aacacaaaat gctgcactgc
      121 ctgatctaat tccttacgac ctaattggtc aaaatatgca atctttaatt ccgtcatttt
      181 atttttcatc cagcggtgcg tgtccttctt ctgctactct tcttttatcc ttagtatctt
      241 catgcttatt aagtgccatc aaggcaaaaa agatcaaatt caaaccacta actacaatgc
      301 caaataattt tattaaattg agtttctttt ctttactcat tttttaacct cacaactaaa
      361 aataatcata aaatgataca tcgcctttaa caaaatctaa ttttttgatg cggtaatctg
      421 taattaatcc tagtttaaca gcagcattca tggttagtct acctaatagc acctgggtcc
      481 acgcggtaat tgatcccgaa aaatcaacca atgcatcttc cttacgttct actgctacct
      541 tacgtccatg attacttaat tgccaaactc caatattcca aggacactgt tcatcgctat
      601 tgacttccag attaaaatca ccttcttgca ttggccgcat acaagccaaa actttttcaa
      661 aatcaataat tcgactcatc atataaggac gcaaatcaac ttggagttcg ttttgttcag
      721 gaaaaagttc agctcgtaac gatttctctg gtacgctcat tttaaattgc ttaacactgc
      781 ccgcgtgcga acccataaaa ccaaacatac tcagtaatcc ctgcggcgta attgcgtaca
      841 tttcatcagc taaaaaagta ttgtctctaa tgcgataaat caagtaacta attggccgct
      901 catccgcgtc aaaataaacg gctacattgc ggtgatgata ataagaatca agtctattcc
      961 accaccatgc ctcacgtaca accgtgttac gttcatcatc agtatgcagt tgacgttcat
     1021 aaagttgaat cacaccattt tgaacagcta aattgtccca cttgccacgc actatatgac
     1081 cagaacgtgg taatttaaaa ctacgcaatg cgcttccatc aaagcgatat tctttttgat
     1141 aaatactatt gctaaacccg tactggcgat aaaagctctc cgaaaatggt gccaggttag
     1201 caaacggaat atcttgccta tgtaagtcat gcaaaatttc tttcattaat tgggaaatat
     1261 gaccttggcc acgatactca ggatatgaag ctacataacc tattccagcc atcggtaaat
     1321 gatgcccaaa aacatcactt ttaaatcgat taaccataat atagctagct aatttttcct
     1381 tatcaaaata gccataacct gtactatgat cataacgact cataaaattt tcgtctttag
     1441 tcaaatcatt atttttcaaa aatgcatatt gaattaatgc cgtaatttgc tttaaattat
     1501 tcttattttt ctttaattcc atgcttattc ctatacgtac atctataaat ttattcatta
     1561 ctattttagt tcatttttta aatttttaac tagatttttc ataaaaataa accggaatca
     1621 taaaatcccg gtttatttta cgcaacgtat tcttgataaa gctgagagat aaatgcctgc
     1681 atctgttcca ctgaatgtct ccggctgcga gcacattctt tagcagggcg atcacataaa
     1741 aagcacttac gtggctgcct gcccaaatct ctgcgtgaaa ttgcagcttg tttatttttt
     1801 accaacacgt ctgcatcaaa gagacgtccc aatgatatct gattctcaaa atcaattgtt
     1861 gagcgcttta ctttttcaat tgacaaagat aatacataaa agttttcaca gccactatca
     1921 tcattaagct gtgtcaccaa tttaaaatga taacctaggt tagtccaagc attttccagc
     1981 tcattgatac ccaacataaa cattttagtt aaatagcgat tattcttgat tggtcctggg
     2041 atattcatct taatgtcgac tagagtttga ttaggatact tattaaaaat cttatgttgt
     2101 acagctactc gcctatcttt agctgctaaa acttgggcaa tatcctgctt ttttccttca
     2161 ttaaaaatat tcatttttat cacccagtta attataaacg attgtgccga ctccgtctgc
     2221 tagtttgttg gcattactca aagaggtgat aattgctaaa ttacctgttt tttctacaaa
     2281 ttcaattgca gcttctatct taggcttcat actcccagct gcgaaataac ctactgctag
     2341 gtattgtttg agctgttcaa cttttatttt accaattgct tgttgatttt ctttgccata
     2401 attcaaaaat gcatgatcca ccgttgttag aattactaat tcatcagcgt tgatatcttc
     2461 tgccatttta gcagcggaaa aatctttatc aattacgccg gcaacacctc tgagatgccc
     2521 atctttcaca ataacaggga tgccaccacc gccacaggca atcggaataa ataaatttcc
     2581 taaagtagcc gccatcactg ctttaattga atgcaatcga ttttcagctt ctgtaaattg
     2641 ccaagcatac tttgaattaa agacctcatc agttacttcc atctcattta agccatattt
     2701 ttcatagatt tcttctccca cctgagttgt tcgatcatga aaagctggca aacaatgcat
     2761 aaagatcaat tggtcatttg gtgtaccagt catttgcatc attttcattg tgaccgtata
     2821 tggctttaat aatttaattc gttcagacca atcattttca cccatcgaaa cccaaacatc
     2881 ggtataaaca acattggctc ctttaacgcc ctgagcaata tcatctgtga tcaaattttt
     2941 tgaacctgaa tcttgggcaa aattttgagc aattttttgt acatcaggat gtgtaaacaa
     3001 aggcttgggt gtaacaatat gtacattaaa acctaacatt gagccacaaa ctaaaagact
     3061 gtcggcaaca ttatcgcggc catcacccac ttccaaacag gaacgccaga atatttagcc
     3121 agctcttcta catcttcttg agcaaaaccg cgatatccaa ttccatcata cattgagcct
     3181 aggactttag ccgtatcctt gacgctttct tttttaccta agtggatctc gcttgcgcct
     3241 agatattctg gatgagcacc taaatcatta caagctacta caaaagcaga tcgcgtccta
     3301 gttgaggctt tttcaaaaag tagtgcaata tttttacctt tcagatattc atgtgggata
     3361 tgctcttttt taagttcttt taaatgtaat gcaaaatcaa ttaaatatga aatttcagct
     3421 ggagtatagt ctttacaatc gagaaaactt ctaccttgaa aaacattttg taaatatttc
     3481 attttttgcc ttttataaat cttcacgaat caacggacac gacatacatc taggaccgcc
     3541 acgaccacgt gagagttcac tagaccgaat ctcatgaacg atgatgccat gttttcttag
     3601 caaatcattg gatacataat tacgatcata agtaacgact tcacctggtg caattgccaa
     3661 ggtatttgag ccgtcattcc attgctcacg tggtgcggca attggatcac caccgccagt
     3721 tggaattaaa tccaattcgc ttaaatgtaa gttttctttc aaaacctgca ccaaatcatt
     3781 cttttctgtg atttttacac cgttgtgatc atcgggctgt agaacataaa tatcaatttt
     3841 gccggcttta tctaaaataa agggatgaac cgtaaattga ttataattaa tcattgtaaa
     3901 aactgtatca aggtgcatca tagcatgatt gtgcggaatc ttaatcgcta aaatcgtatc
     3961 ataacttgaa tgatcaaata aattatgagc taagtcagta attgcagttg cagaagtgcg
     4021 ttgtgaaata cctacagcta acacatggtt atttagaact agttcatccc cgccctcaag
     4081 gcgaccatga tgataacggt cacgccaaac tggaatagtt gcgttcttga aatcaggatg
     4141 atttttcaaa attgtttcca taaataatga ttcacgtcgt ctagctctga aagtcatccg
     4201 gttaatggtc atccctgaac caattgcagc ctgttgatct cgagtaaaat atacatttgg
     4261 cattggatca agataaaaag ggtaatctgg gtcctcagcc aaatctgcta aagatggggt
     4321 agaattatga atcgcacttt ttctaattcc agcaatcacc gtttttacca tttccttagt
     4381 tagcaattct tggagatagt tcagcaataa ttgatgcaaa ggatcctgtt ttttaatact
     4441 tgattcatcc agtaactgat ctaagaatgc ccgacgaact ttctcatctg ttaaagattc
     4501 tgctaataaa tcctcaagat ataatacttt gatcccctgc tgcctcaata catgcgcaaa
     4561 agcatcatgt tcttcttggg caatcttcag ataaggaata tcgtcaatca acattcgatg
     4621 caaaatatct ggggctagat tttctagttc ttttcccggt cgatgtaaca tcaccgtttt
     4681 taacttacca atttctgaat aaacatgaat cggactcgac attcaaccac cttctattaa
     4741 ttattgtacc cgtttacatt tattatggat caattaggca aaagttacag tattatcata
     4801 ttgcagcaat gatttttttc attaaaggtg taacttgatg atctttacgc caaaccagtt
     4861 gcaaatgtgt tatccaatta gcatgtttaa ttgcgatcat attttcttgg gcataagttg
     4921 tcgcaattga ttctggtact agcgctactc ccatttttct cttggcccaa gtaattgctg
     4981 tccgtgaatc atcacactta accgcataaa atggcttaag cccatgatgt gcaaaagttt
     5041 gattaaaaat atcctcaaag cggcgataaa taatcaatgg ctgatctgct agatctttaa
     5101 tgcgtaattc ttttttttgc tgaaaatctg ggtctacact aatagccatc attttttcag
     5161 ttgttaaagt cttagtattt aaacctgtct ggttgtaagg cgttcgtaca atgcctagat
     5221 cgattgtctt tttttctaat ttatccagga tgccataagt attatcttca taaatatcaa
     5281 aagaaatttc cggataatat tttcgtaatt cattaaaaga attcattggt atcaagcccg
     5341 ttgaggaaga tgccattcca attgcaatcg ttcccaattc accggaaata gtcttatgta
     5401 cttggttttc agcattttga gctagagaaa taatttcatt ggcatagctt tgaaaaattt
     5461 gtcccacatc agttagctca ataccatgtg ccgttctttt aaataattgc gcgcccaact
     5521 ctttctctaa ttgttttaat tgatagctta atggtggctg tgcaatatac aagcgcttag
     5581 cagctgctgt aatctgcttt tcttctgcta caactagaaa ataacgtaac tgttttagat
     5641 tcatattatt tatccttttt ttatttcaat tgatagtgat attaaaatat ttaatatctt
     5701 atattgtatt ttagtatttt attcatagca atatctgtgc taccttatta aggtagattt
     5761 ggagggaaaa taatgtctga taaatttcac ggcttaactc aagccgaagc agacaagcgc
     5821 ttaaaagaag atggcttaaa tgaagtacca gagcctgaat acaatttctt taaagagttc
     5881 ttgtctaagt tatggaacct atccgcttgg attctagaag ctgctttaat tctagaatgt
     5941 atcttgggca aatgggtcca atcattattc gtgttgttga tgcttttatt tgctgcattt
     6001 aacggtgcat ctaagaaaaa gcaatcaaga cgagttttaa ataatatttc acacaagttg
     6061 actcctactg tatcagttga acgcgatggc aagtggatca aacttgattc taaacaacta
     6121 gttaaaggcg atttaatctc acttaaacgc ggggacgtac tcgcagcaga tgttaaaatt
     6181 gttgacggta acttagcttg tgatgaaagc tcaattacag gtgaatctaa accagttaag
     6241 aaagcaattg atgacaccgc ctttgccggt actacagttg ttgaaggtga tggcctagct
     6301 gttgttactg ctacaggtaa agattctaga agcggtaaga cgattaattt gatcaacaat
     6361 tccgctgctc ctggtcactt acaacaactt ttgactaaga ttatctacta cctttgctta
     6421 ctagatggtg ttttaacctt agttattatt atcgcctcct tcttcaaagg cggtaatttc
     6481 aataccttta ttaatatgtt gccattcctg gcaatgatgt ttattgcttc aattcctgta
     6541 gcaatgccat caacttttgc tttatccaac tcatttgaag caacacgctt aagtaaagaa
     6601 ggagtcctga cttctgacct aactggaatt caggacgcag ctaacttgaa cttgctttta
     6661 cttgataaga ctggaacaat tacggaaaac aaaactgccg tagccgcttg gactaatcta
     6721 agtgacttgc ctgataaaga cgtgcttgct ttagctggag ccgcaactga taaacgtaat
     6781 gctggtatta tcgatacagc aatcgatgaa tacttagtag aaaataacat tccagtcatg
     6841 aatgctgaaa actttactcc atttacttct gacactggtt attctatggc tgatgttgct
     6901 ggacataatg taaagcttgg ttcatttaag caattatcct tgatcgataa acatgccgat
     6961 gaagaaattt ctggaattaa tttcaaggca ggacgctcag tagcagtctt gattgacgat
     7021 aagttagctg gtgtcttcat cttacaagat aaagttagaa cagactctaa agcagctttg
     7081 gctgaactca agaaacgtgg cgttcgcccg attatgttaa ctggtgacaa tcaaaagacc
     7141 gctgctgcag tggcagaaca agttgattta actggtgaag taatttcgat tcacgatttc
     7201 aatgaaaata ctgatattaa tgatttggcc ggtattgctg atgttttacc agaagataaa
     7261 ctcaagatgg taaagctttt ccaagaaaaa ggctatatcg tagggatgac tggtgacgga
     7321 gttaacgacg cacctgcatt aaaacaagct gaagtaggaa tcgcggtttc aaatgctgct
     7381 gacgtagcta agcgttcggg taaaatggta ttactagacg atggtctagg ctcaattgtt
     7441 aaaattttag acgctggaca tcgcgtatac caaagaatga ctacttggtc actaaccaag
     7501 cttgctagaa ctgctgaatt aacgatgctg ttaacttttg gctatctttt ctttgactac
     7561 atcccaatgg ccttgaatgc aatggttatc tataccatta tgaacaatat ggttacgatg
     7621 atgattggga ccgaccggac tcacattact tataagccag aaaactggaa tatggctaag
     7681 cttgctaaga tcgccttttc actagctgct ggttggactc taattggtat tgggtttgtt
     7741 tggttcttaa acacacacgg ttggagtcac ggtgctgttt ctactatggt ttacgtatac
     7801 ctagttctta gcgcaatgtt gattgttttg attactagaa ctcgtaagta cttttggcaa
     7861 gattacccat ccaagttggt tggtagtgtt caaattgcag atgttctatt gacctttatc
     7921 ttagctcttt gtggttgggc aatggtccaa atttctattc aaaatctagc aatcaccgta
     7981 attgtagcga ttattgctgc cataataatt gacttaattt accaacctgt gatgaaaaac
     8041 agatagatta ttaccataaa aattttataa attaaaagac ttctaggaac tttgaactct
     8101 tagaagtctt ttaatttatc ttttttgatt cacgatatcc tactgcacgt gctgctgctt
     8161 tactcttgaa gaaaactgca ttttcacgat tcattcgata attatgaccg cgcattacgt
     8221 gaaagatttt tgatcgttta ttaccaacaa ttctgtaatt actggtataa atcttagttt
     8281 tatcacgata ttgatgcttt ctccttctgt gatgaatagc tgcattaaca actgatgtcg
     8341 atccctgcaa atttgcaggc agaatactga tttctcaaac taacatcagc aatgcaacaa
     8401 tagtcacaac ccaattcttg catcttttca taaaaacact cccttaatat gtcactatat
     8461 ttatatggta tacgcatata tgaagtgttc ctacgtttat tagaacctag tttcaattac
     8521 ttatcttcat ttgcaccaaa aatatccaaa aattgtaaaa acaagttaac aaaatcaaga
     8581 tataattgca aagcacctaa aactgcaagc ccattagttg aaagatcatc accatattgt
     8641 aaataaatat ctttcattct ttgtgcatcc cacgcagtta aaatagtaaa tataatcaca
     8701 gcaataatcg aaaaaacgta gtcaatgatt ggattatgta aaaataaatt agctaacatg
     8761 gctacaatca acccaattaa cgcagcagaa gcataagacc ctattcgact caaatctttt
     8821 ttggtaattg ttcctaaaat cgccattgtt acaaagacgg ttgccgaagc tacaaatgct
     8881 gaagcaatat tttgtccact atatgcacct gcaataaaag caaaggtaac gccgtaaaca
     8941 attggtgttg tgcaataaag gcagagatag gtcccgcaaa aaccgtcatt gtcaaatatg
     9001 cactaattgc tgaaacgaaa accgctaagg ccatataacc atatattttg ctaaaaaaca
     9061 tttaatcctg aatcattagc atattgctgt tgaccagatt cttgatcaaa attatccatc
     9121 ttaatttctc cttcttaaca cataccctgt actttaaata taacacctgt ttaattaaaa
     9181 acgtagcgag acaccctacc aaaatataaa ctatctcggt tcctttggac tagacctata
     9241 ataaaaaata tcatataatt ggtatagaca attatcaaaa aatgaggtac tattatgaca
     9301 atgagatctt taggtctgtc aatttatcca ggccacagca aatttgaagg caacgctcac
     9361 tatctggact tagctcacaa atatggcttt tctcgtatct tcatgagtat gcttgaagta
     9421 caaggcagcc ctgaagaaac caaagctaag tataaaaaaa tcattgaata tggcaataaa
     9481 ttgggatttc aaactttttt agatgttaat cctgcaatct tcaaacaact aggtgtcagc
     9541 tatgatgacc tgaaattttt tgctgatatt ggtgcagcag gcatccgtct tgacacaaca
     9601 tttgatggtg caattgaagc aatgctttct tacaacccat atggtctaat cattgaactc
     9661 aacatgagta ataatgttga ctatcttaac aatattattt cttaccaagc taatacaccg
     9721 tttatttatg gctgtcacaa tttttatcct caacgcggta ctggcttacc ttacgacttc
     9781 tttatcgctt gttctgaacg cttcaaaaag tttggcattc attcagccgc ttttgtctca
     9841 agtcaagtag gtcaaatggg accttggaac gtggaagatg gtttaccaac gcttgagcaa
     9901 gaccgtaatt taccaattga tgtgcaagca atgcatctct gggcttctgg gttgattgat
     9961 gatgtaatca tcggtaatgc ttatgccagt gaagccgagt taaaagcctt atctaaagtt
    10021 aatcgctatc aattgatgtt gcacgtaaac tacgttactg atgttaataa gattgagaaa
    10081 actatcgtag aagcgcctca acatttccgt cgtggtgata tcactaagga tataattcgt
    10141 tcaaccatgc cccgtgtaac ttatgcagat attcctaatc cagtacacga caacaatgta
    10201 gaattccaac gcggagatat tatcattggt aacgacaact ttggtcatta caaaaatgaa
    10261 ctacaaattg tccttgaacc tcataaggag tcaaggatga acaaagtcgg ttctattaga
    10321 tcagacgaat tattcctgct cgactttatt aaaccatggt caaaatttaa attaatcggt
    10381 aacaaataat aaaaacacct catgtcatta tctgtagaca cgaggtgttt ttctacttga
    10441 ataaatcgtt aaaactttcg ctcattgttg ggtgagtata gatttgatca cgcaaaatat
    10501 ttgctggaat cttcattttc attgccatac taatttgatt aattagctca taagattcgg
    10561 caccataaag agtgacgcca agaatttggt tgtttgcagg attaattaat gctttaaata
    10621 aaccgcgtgg atccttcaat acttgagcct taggaatagc agttactggc agtttcttta
    10681 attcatattt gatattttgg gattttgctt ccttttcatt caagccgacg cgagataatg
    10741 tcggcgtaat gaatacactg tatggtacat tgattcgatt actgactctt ctttgagcat
    10801 ccccatataa ttgatccttg ataatccgaa aatcatcaag tgaaatatag gtaaattgcg
    10861 gaccgccttt gacatcacca attgcccaaa cattttcgac gttagttctt agataatcat
    10921 caaccataat tgtgccacga tcattcaatt caatatcagt attttctatt ccaagatcct
    10981 cagtatttgg ttttcttcct gtggctacta aaattctatc agcaactgtt gttgtagtca
    11041 cgccatcttt ttcatagtaa acagtatggt catctattct actgatcttc actcctaact
    11101 caaatttcac gccactattt tcaagatcat gctttatctc gaccgcaatg tcatcgtctt
    11161 cacgtggtaa aaagttatca tgtaaatcaa gcacagttac ttctgagcca tattctgcaa
    11221 acatcgatgc aaattctaga ccaatgtaac cagcaccaat aatcactagt tttttaggta
    11281 aatttgtttg atccattgca gcagtcgaat caagaatagc attactttcc attaaaccag
    11341 gaattggcaa cataacaggc aaagcaccag tattgataaa aattctgtca ccatgaaatt
    11401 cttcgatttg accatttacc gtggttactg caatttcatg attatttata aacttagcgg
    11461 tgccgttaag tacggtaaca ttctcttcat ctgctaacat atgataattc ttgttccgta
    11521 gcattgaagt catatcattt ttgccattga ccgcgtcaac aaaatcaacg ccattatcag
    11581 cttcgataat taaacgctta gatggcaaac atgcaatatt aatacaagtt ccaccataca
    11641 tcttatctga cttctcaaca actaagactt cttcaccttt ttgtgctaaa aatttagcta
    11701 gagtcttacc acctttacca aaaccaataa taatgttctt tacatttttc ataattacgc
    11761 ctccctattc ttaatatcct gttttcctta ttgtgggcga tcaagaataa tttatcatct
    11821 tttttgcttt agaataaaaa acaaatcctc ctaaaagcga gtcgccttta agaggattgc
    11881 tatgaatttc tgttgatcgg gcatcgtgaa caaggattct cgatgcaaca ctttctttag
    11941 tataacgatc tttgcaaatt agatcaagcg cgatttttat tagatatgtg ctaaaagcca
    12001 actattcctg atcaaatgtt ttttctatgt gataccatgg agatggattt tcgaatatat
    12061 tctagtccat aacaccaatg actataatac tttttaggaa atagtttagt tagaaaacca
    12121 gccattaagg attcaatcaa tatttttgga aaggtcaaca aatgaaacat aaatcattaa
    12181 ttacaacttt agcagcaatc atgctaatcg ggagtgttgg tactgttaca acagctacat
    12241 cacaacctgt gctggcaatt agtaaacatt catagcattg gcacgaagtc aaaactacaa
    12301 aagatgtaag agtttataag cttagatatc cgctttacaa aactccaaaa tttagttttt
    12361 gacttgaaaa aggatcatat gttgatatta gatgttttag taataaccat tattttgaag
    12421 ttagaggtgg tctaggtcga ggcactcata tcataaaagg ctcatctacc agatggttca
    12481 gaaacgaata aaaaatattg atatcaaaaa atgtactgag acgtaaaaag tagacaatta
    12541 aaatattgga ttaatagagg cttgacttcg atactctttc ggggttaagc cttttggcaa
    12601 aagccttgtc attactaaat ccatatctgg atgtttggag atagtataag aaactatatc
    12661 gccaccgcag ccgtctagaa taggcgataa ataaagcttt tcattattaa gatgaaattc
    12721 agtgatatca gtataccgtt ttgtgttagg cagggctgcg aagaaatcac gatgaattaa
    12781 atttggagct attttgccaa tagtaccttt atagcttgaa tatttgcgct tattgcgcct
    12841 gatgccttta agacctaatt tatgcatcca atagcgaacg gttttctccg taactttcca
    12901 gccctttctg attaactgca aagctactct gcgatatcca tagcggcctt gatgatgatt
    12961 aaaaatctca tggattctag caataagctt tgaccgttta ggcttgacgg gctgtcgtct
    13021 gataatcttg tagtatgagc ttctggcaat tataggtagc tcagggtgct ctgcaatcgc
    13081 agctaataca taatttaaac taactttgaa ttcttgcctt agatccgtaa tcaccctagc
    13141 tatttcttct gatcttcttg atccaaggca cttagttttt ttacgtattc gttcacaata
    13201 cgcaatcgca agttttcttc tttcagctgc tggatctctt tggaatagct ttggttttta
    13261 gtagttaaaa tttctattcc atgcatatca attaatctaa gcatatagtc taaattagct
    13321 agattcattc tgtacgcttt agccaattga ctgattgaga tattttcatc tttccattta
    13381 tgataaattt ctattttttg ttctttatta aatttagaca tagtaaaatg aagccaaact
    13441 tcttattatg cttgacttta cgtagaaaaa gacctaaaag tgtctaactt ttaggtctca
    13501 gttcaaattg atttaattcc ctctttttat ttattctatt ttaagcacca tgatattgaa
    13561 caagtgaata aatatcaaca tcaggtaatt tatctctacc gtgtaaatct ggcaattcga
    13621 tgtagaatgc ggcaccgact aacttaccac caaggttttc aattagctct ttagaagctc
    13681 ttaaagtacc tgcggtagcc atcaagtcat cacagacaac cactctttgt ccaggtttaa
    13741 tcgcatcctt gtgcatttcc aaactgtttg aaccatattc caaatcatag gaagcacgtt
    13801 caacttctct tggtaactta tgtggctttc ttgcaggtac aaaacctaaa cctaactcag
    13861 tagctactgg acaacctaca ataaaaccac gtgcttcagg cccaacaatt acatctgctt
    13921 ttttactctt tgcatattcc gctaattcat gagtagcggc acgatacaat tcaccatctt
    13981 gcaaaattgg tgtaatatcg cgaaaaacaa tgcctttgtt aggaaaatcc ttaacacttg
    14041 caatatattt actaaaatca actgccataa gaagcataac ctccaaaatt ctctgtgttt
    14101 gtgttcaaac gcttttgacc agtatatttt aacaaatttt aacgataaaa gcactgaaaa
    14161 cagaatagtt atctatttat ttgtcaaatt attaacatat gtaatcaaac gttgactagg
    14221 catagttctt agttgattaa caaatttaat ctgagaagaa gttcccatta aatatttaga
    14281 agctgtcagc ggctgttttt taggagaagg ctctcctacc aatttacctt catccaattt
    14341 tacaaagcct aattcaaaga aaactcgtaa aatgaaaagc acactatcat aatctagtcc
    14401 caaataaggt gcaactgtac ggtaatctgc tggctttaac gtagggtgac tataaatata
    14461 ttttaaaaca gcaccaaaat aatttttagc gggaatttgt tcaacaggca attgatcaag
    14521 caaaaagcgt aaatagattt gttgataatc tttctccaat gcagcattta attcaatctg
    14581 attgcgtggc acatctaata atgcaactgt ttcaccagtt tgatcataat ctttaactaa
    14641 agagatcttg tcttcatcga tctgtagtcg gttgcgaaca atcggaatat ttttttgatc
    14701 aaataacagg tagcggtccg cg
//
